| Year |
Citation |
Score |
| 2019 |
Mukohda M, Fang S, Wu J, Agbor LN, Nair AR, Ibeawuchi SC, Hu C, Liu X, Lu KT, Guo DF, Davis DR, Keen HL, Quelle FW, Sigmund CD. RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity. The Journal of Clinical Investigation. 130. PMID 30896450 DOI: 10.1172/Jci123462 |
0.303 |
|
| 2019 |
Umesalma S, Kaemmer CA, Kohlmeyer JL, Letney BL, Schab AM, Reilly JA, Sheehy RM, Hagen J, Tiwari N, Zhan F, Leidinger MR, O'Dorisio TM, Dillon JS, Merrill RA, Meyerholz DK, ... ... Quelle FW, et al. RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth. The Journal of Clinical Investigation. PMID 30721156 DOI: 10.1172/Jci123049 |
0.542 |
|
| 2017 |
Mukohda M, Lu KT, Guo DF, Wu J, Keen HL, Liu X, Ketsawatsomkron P, Stump M, Rahmouni K, Quelle FW, Sigmund CD. Hypertension-Causing Mutation in Peroxisome Proliferator-Activated Receptor γ Impairs Nuclear Export of Nuclear Factor-κB p65 in Vascular Smooth Muscle. Hypertension (Dallas, Tex. : 1979). PMID 28507170 DOI: 10.1161/Hypertensionaha.117.09276 |
0.387 |
|
| 2017 |
Hu C, Keen HL, Lu KT, Liu X, Wu J, Davis DR, Ibeawuchi SC, Vogel S, Quelle FW, Sigmund CD. Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin. Jci Insight. 2: e91738. PMID 28352663 DOI: 10.1172/Jci.Insight.91738 |
0.308 |
|
| 2016 |
Agbor LN, Ibeawuchi SC, Hu C, Wu J, Davis DR, Keen HL, Quelle FW, Sigmund CD. Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism. Jci Insight. 1: e91015. PMID 27882355 DOI: 10.1172/Jci.Insight.91015 |
0.323 |
|
| 2015 |
Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD. Endothelial PPARγ Provides Vascular Protection from IL-1β-Induced Oxidative Stress. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00490.2015. PMID 26566726 DOI: 10.1152/Ajpheart.00490.2015 |
0.344 |
|
| 2015 |
Ibeawuchi SR, Agbor LN, Quelle FW, Sigmund CD. Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. The Journal of Biological Chemistry. 290: 19208-17. PMID 26100637 DOI: 10.1074/Jbc.M115.645358 |
0.411 |
|
| 2014 |
Hagen J, Muniz VP, Falls KC, Reed SM, Taghiyev AF, Quelle FW, Gourronc FA, Klingelhutz AJ, Major HJ, Askeland RW, Sherman SK, O'Dorisio TM, Bellizzi AM, Howe JR, Darbro BW, et al. RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner. Cancer Research. 74: 6661-70. PMID 25273089 DOI: 10.1158/0008-5472.Can-13-3742 |
0.513 |
|
| 2014 |
Reed SM, Hagen J, Tompkins VS, Thies K, Quelle FW, Quelle DE. Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53. Cell Cycle (Georgetown, Tex.). 13: 1288-98. PMID 24621507 DOI: 10.4161/Cc.28202 |
0.371 |
|
| 2013 |
Quelle FW, Sigmund CD. PPARγ: no SirT, no service. Circulation Research. 112: 411-4. PMID 23371897 DOI: 10.1161/Circresaha.113.300870 |
0.346 |
|
| 2009 |
Lei H, Quelle FW. FOXO transcription factors enforce cell cycle checkpoints and promote survival of hematopoietic cells after DNA damage. Molecular Cancer Research : McR. 7: 1294-303. PMID 19671690 DOI: 10.1158/1541-7786.Mcr-08-0531 |
0.737 |
|
| 2008 |
Nimbalkar D, Quelle FW. Phosphoinositide 3-kinase signaling overrides a G2 phase arrest checkpoint and promotes aberrant cell cycling and death of hematopoietic cells after DNA damage. Cell Cycle (Georgetown, Tex.). 7: 2877-85. PMID 18769155 DOI: 10.4161/Cc.7.18.6675 |
0.743 |
|
| 2007 |
Quelle FW. Cytokine signaling to the cell cycle. Immunologic Research. 39: 173-84. PMID 17917064 DOI: 10.1007/S12026-007-0080-5 |
0.573 |
|
| 2005 |
Korgaonkar C, Hagen J, Tompkins V, Frazier AA, Allamargot C, Quelle FW, Quelle DE. Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function. Molecular and Cellular Biology. 25: 1258-71. PMID 15684379 DOI: 10.1128/Mcb.25.4.1258-1271.2005 |
0.398 |
|
| 2005 |
Chakravarti P, Henry MK, Quelle FW. Prolactin and heregulin override DNA damage-induced growth arrest and promote phosphatidylinositol-3 kinase-dependent proliferation in breast cancer cells. International Journal of Oncology. 26: 509-14. PMID 15645137 DOI: 10.3892/Ijo.26.2.509 |
0.555 |
|
| 2004 |
Henry MK, Nimbalkar D, Hohl RJ, Quelle FW. Cytokine-induced phosphoinositide 3-kinase activity promotes Cdk2 activation in factor-dependent hematopoietic cells. Experimental Cell Research. 299: 257-66. PMID 15302592 DOI: 10.1016/J.Yexcr.2004.06.003 |
0.766 |
|
| 2003 |
Friedman AD, Nimbalkar D, Quelle FW. Erythropoietin receptors associate with a ubiquitin ligase, p33RUL, and require its activity for erythropoietin-induced proliferation. The Journal of Biological Chemistry. 278: 26851-61. PMID 12746455 DOI: 10.1074/Jbc.M210039200 |
0.74 |
|
| 2003 |
Nimbalkar D, Henry MK, Quelle FW. Cytokine activation of phosphoinositide 3-kinase sensitizes hematopoietic cells to cisplatin-induced death. Cancer Research. 63: 1034-9. PMID 12615719 |
0.768 |
|
| 2001 |
Eapen AK, Henry MK, Quelle DE, Quelle FW. DNA damage-induced G1 arrest in hematopoietic cells is overridden following phosphatidylinositol 3-kinase-dependent activation of cyclin-dependent kinase 2 Molecular and Cellular Biology. 21: 6113-6121. PMID 11509654 DOI: 10.1128/Mcb.21.18.6113-6121.2001 |
0.782 |
|
| 2001 |
Henry MK, Lynch JT, Eapen AK, Quelle FW. DNA damage-induced cell-cycle arrest of hematopoietic cells is overridden by activation of the PI-3 kinase/Akt signaling pathway. Blood. 98: 834-41. PMID 11468186 DOI: 10.1182/Blood.V98.3.834 |
0.773 |
|
| 1998 |
Quelle FW, Wang J, Feng J, Wang D, Cleveland JL, Ihle JN, Zambetti GP. Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways. Genes & Development. 12: 1099-107. PMID 9553040 DOI: 10.1101/Gad.12.8.1099 |
0.647 |
|
| 1997 |
Ihle JN, Nosaka T, Thierfelder W, Quelle FW, Shimoda K. Jaks and Stats in cytokine signaling. Stem Cells (Dayton, Ohio). 15: 105-11; discussion 1. PMID 9368330 DOI: 10.1002/Stem.5530150814 |
0.552 |
|
| 1996 |
Quelle FW, Wang D, Nosaka T, Thierfelder WE, Stravopodis D, Weinstein Y, Ihle JN. Erythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response. Molecular and Cellular Biology. 16: 1622-31. PMID 8657137 DOI: 10.1128/Mcb.16.4.1622 |
0.5 |
|
| 1996 |
Shimoda K, van Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, Chu C, Quelle FW, Nosaka T, Vignali DA, Doherty PC, Grosveld G, Paul WE, Ihle JN. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene. Nature. 380: 630-3. PMID 8602264 DOI: 10.1038/380630A0 |
0.447 |
|
| 1995 |
Copeland NG, Gilbert DJ, Schindler C, Zhong Z, Wen Z, Darnell JE, Mui AL, Miyajima A, Quelle FW, Ihle JN. Distribution of the mammalian Stat gene family in mouse chromosomes. Genomics. 29: 225-8. PMID 8530075 DOI: 10.1006/Geno.1995.1235 |
0.313 |
|
| 1995 |
Quelle FW, Shimoda K, Thierfelder W, Fischer C, Kim A, Ruben SM, Cleveland JL, Pierce JH, Keegan AD, Nelms K. Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis. Molecular and Cellular Biology. 15: 3336-43. PMID 7760829 DOI: 10.1128/Mcb.15.6.3336 |
0.423 |
|
| 1995 |
Quelle FW, Thierfelder W, Witthuhn BA, Tang B, Cohen S, Ihle JN. Phosphorylation and activation of the DNA binding activity of purified stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor Journal of Biological Chemistry. 270: 20775-20780. PMID 7657660 DOI: 10.1074/Jbc.270.35.20775 |
0.564 |
|
| 1995 |
Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Silvennoinen O. Signaling through the hematopoietic cytokine receptors Annual Review of Immunology. 13: 369-398. PMID 7612228 DOI: 10.1146/Annurev.Iy.13.040195.002101 |
0.538 |
|
| 1995 |
Yin T, Keller SR, Quelle FW, Witthuhn BA, Tsang ML, Lienhard GE, Ihle JN, Yang YC. Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases. The Journal of Biological Chemistry. 270: 20497-502. PMID 7544789 DOI: 10.1074/Jbc.270.35.20497 |
0.48 |
|
| 1995 |
Azam M, Erdjument-Bromage H, Kreider BL, Xia M, Quelle F, Basu R, Saris C, Tempst P, Ihle JN, Schindler C. Interleukin‐3 signals through multiple isoforms of Stat5. The Embo Journal. 14: 1402-1411. DOI: 10.1002/J.1460-2075.1995.Tb07126.X |
0.461 |
|
| 1994 |
Stahl N, Boulton TG, Farruggella T, Ip NY, Davis S, Witthuhn BA, Quelle FW, Silvennoinen O, Barbieri G, Pellegrini S, Ihle JN, Yancopoulos GD. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 β receptor components Science. 263: 92-95. PMID 8272873 DOI: 10.1126/Science.8272873 |
0.472 |
|
| 1994 |
Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O. Signaling by the cytokine receptor superfamily: JAKs and STATs Trends in Biochemical Sciences. 19: 222-227. PMID 8048164 DOI: 10.1016/0968-0004(94)90026-4 |
0.494 |
|
| 1994 |
Yamamoto K, Quelle FW, Thierfelder WE, Kreider BL, Gilbert DJ, Jenkins NA, Copeland NG, Silvennoinen O, Ihle JN. Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation Molecular and Cellular Biology. 14: 4342-4349. PMID 8007943 DOI: 10.1128/Mcb.14.7.4342 |
0.51 |
|
| 1994 |
Quelle FW, Sato N, Witthuhn BA, Inhorn RC, Eder M, Miyajima A, Griffin JD, Ihle JN. JAK2 associates with the βc chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region Molecular and Cellular Biology. 14: 4335-4341. PMID 8007942 DOI: 10.1128/Mcb.14.7.4335 |
0.511 |
|
| 1994 |
Ihle JN, Witthuhn B, Tang B, Yi T, Quelle FW. 2 Cytokine receptors and signal transduction Bailliere's Clinical Haematology. 7: 17-48. PMID 7518712 DOI: 10.1016/S0950-3536(05)80005-8 |
0.426 |
|
| 1994 |
Miura O, Nakamura N, Quelle F, Witthuhn B, Ihle J, Aoki N. Erythropoietin induces association of the JAK2 protein tyrosine kinase with the erythropoietin receptor in vivo Blood. 84: 1501-1507. DOI: 10.1182/Blood.V84.5.1501.Bloodjournal8451501 |
0.543 |
|
| 1994 |
Miura O, Miura Y, Nakamura N, Quelle F, Witthuhn B, Ihle J, Aoki N. Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor Blood. 84: 4135-4141. DOI: 10.1182/Blood.V84.12.4135.Bloodjournal84124135 |
0.558 |
|
| 1993 |
Silvennoinen O, Witthuhn BA, Quelle FW, Cleveland JL, Yi T, Ihle JN. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction Proceedings of the National Academy of Sciences of the United States of America. 90: 8429-8433. PMID 8378315 DOI: 10.1073/Pnas.90.18.8429 |
0.49 |
|
| 1993 |
Witthuhn BA, Quelle FW, Silvennoinen O, Yi T, Tang B, Miura O, Ihle JN. JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin Cell. 74: 227-236. PMID 8343951 DOI: 10.1016/0092-8674(93)90414-L |
0.537 |
|
| 1993 |
Ihle JN, Quelle FW, Miura O. Signal transduction through the receptor for erythropoietin Seminars in Immunology. 5: 375-389. PMID 8260653 DOI: 10.1006/Smim.1993.1043 |
0.543 |
|
| 1993 |
Watling D, Guschin D, Müller M, Silvennoinen O, Witthuhn BA, Quelle FW, Rogers NC, Schindler C, Stark GR, Ihle JN, Kerr IM. Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-γ signal transduction pathway Nature. 366: 166-170. PMID 7901766 DOI: 10.1038/366166A0 |
0.326 |
|
| 1992 |
Quelle DE, Quelle FW, Wojchowski DM. Mutations in the WSAWSE and Cytosolic Domains of the Erythropoietin Receptor Affect Signal Transduction and Ligand Binding and Internalization Molecular and Cellular Biology. 12: 4553-4561. PMID 1406645 DOI: 10.1128/Mcb.12.10.4553 |
0.43 |
|
| 1992 |
Quelle FW, Egerton M, Samelson LE, Wojchowski DM. Cytokine-induced phosphorylation of pp100 in FDC-ER cells is at tyrosine residues Biochemical and Biophysical Research Communications. 188: 1040-1046. PMID 1280128 DOI: 10.1016/0006-291X(92)91336-O |
0.452 |
|
| 1989 |
Quelle FW, Caslake LF, Burkert RE, Wojchowski DM. High-level expression and purification of a recombinant human erythropoietin produced using a baculovirus vector Blood. 74: 652-657. PMID 2752139 DOI: 10.1182/Blood.V74.2.652.Bloodjournal742652 |
0.381 |
|
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