Patrick Brennwald - Publications

Affiliations: 
Weill Cornell Medical College, New York, NY, United States 
Area:
Cell Biology, Molecular Biology

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Miller BK, Rossi G, Hudson S, Cully D, Baker RW, Brennwald P. Allosteric regulation of exocyst: Discrete activation of tethering by two spatial signals. The Journal of Cell Biology. 222. PMID 36729146 DOI: 10.1083/jcb.202206108  0.404
2021 Urbina FL, Menon S, Goldfarb D, Edwards R, Ben Major M, Brennwald P, Gupton SL. TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47. Cell Reports. 34: 108743. PMID 33567284 DOI: 10.1016/j.celrep.2021.108743  0.327
2020 Rossi G, Lepore D, Kenner L, Czuchra AB, Plooster M, Frost A, Munson M, Brennwald P. Exocyst structural changes associated with activation of tethering downstream of Rho/Cdc42 GTPases. The Journal of Cell Biology. 219. PMID 31904797 DOI: 10.1083/Jcb.201904161  0.509
2020 Munson M, Lepore D, Feyder M, Rossi G, Czuchra AB, Kenner L, Martínez-Núñez L, Frost A, Brennwald P. Activation of the Exocyst Tethering Complex for SNARE Complex Regulation and Membrane Fusion The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00212  0.478
2020 Munson M, Lepore D, Feyder M, Rossi G, Czuchra AB, Kenner L, Martinez-Nunez L, Forson JM, Frost A, Brennwald P. Exocyst Tethering Complex Regulation of SNARE Proteins and Membrane Fusion Biophysical Journal. 118: 340a-341a. DOI: 10.1016/J.Bpj.2019.11.1896  0.531
2018 Rossi G, Watson K, Kennedy W, Brennwald P. The tomosyn homolog, Sro7, is a direct effector of the Rab GTPase, Sec4, in post-golgi vesicle tethering. Molecular Biology of the Cell. mbcE18020138. PMID 29668350 DOI: 10.1091/Mbc.E18-02-0138  0.568
2015 Watson K, Rossi G, Temple B, Brennwald P. Structural basis for recognition of the Sec4 Rab GTPase by its effector, the Lgl/tomosyn homologue, Sro7. Molecular Biology of the Cell. 26: 3289-300. PMID 26202462 DOI: 10.1091/Mbc.E15-04-0228  0.486
2014 Watson LJ, Rossi G, Brennwald P. Quantitative analysis of membrane trafficking in regulation of Cdc42 polarity. Traffic (Copenhagen, Denmark). 15: 1330-43. PMID 25158298 DOI: 10.1111/tra.12211  0.396
2013 Brennwald P. Membrane traffic: the exocyst meets the cell cycle. Current Biology : Cb. 23: R838-40. PMID 24070443 DOI: 10.1016/J.Cub.2013.08.007  0.421
2011 Forsmark A, Rossi G, Wadskog I, Brennwald P, Warringer J, Adler L. Quantitative proteomics of yeast post-Golgi vesicles reveals a discriminating role for Sro7p in protein secretion. Traffic (Copenhagen, Denmark). 12: 740-53. PMID 21477180 DOI: 10.1111/J.1600-0854.2011.01186.X  0.374
2011 Rossi G, Brennwald P. Yeast homologues of lethal giant larvae and type V myosin cooperate in the regulation of Rab-dependent vesicle clustering and polarized exocytosis. Molecular Biology of the Cell. 22: 842-57. PMID 21248204 DOI: 10.1091/mbc.E10-07-0570  0.484
2010 Wu H, Brennwald P. The function of two Rho family GTPases is determined by distinct patterns of cell surface localization Molecular and Cellular Biology. 30: 5207-5217. PMID 20823269 DOI: 10.1128/Mcb.00366-10  0.472
2010 Boulter E, Garcia-Mata R, Guilluy C, Dubash A, Rossi G, Brennwald PJ, Burridge K. Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1. Nature Cell Biology. 12: 477-83. PMID 20400958 DOI: 10.1038/Ncb2049  0.589
2010 Ivanov AI, Young C, Den Beste K, Capaldo CT, Humbert PO, Brennwald P, Parkos CA, Nusrat A. Tumor suppressor scribble regulates assembly of tight junctions in the intestinal epithelium. The American Journal of Pathology. 176: 134-45. PMID 19959811 DOI: 10.2353/Ajpath.2010.090220  0.454
2010 Wu H, Turner C, Gardner J, Temple B, Brennwald P. The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis Molecular Biology of the Cell. 21: 430-442. PMID 19955214 DOI: 10.1091/Mbc.E09-06-0501  0.5
2008 Wu H, Rossi G, Brennwald P. The ghost in the machine: small GTPases as spatial regulators of exocytosis Trends in Cell Biology. 18: 397-404. PMID 18706813 DOI: 10.1016/J.Tcb.2008.06.007  0.55
2007 Brennwald P, Rossi G. Spatial regulation of exocytosis and cell polarity: yeast as a model for animal cells. Febs Letters. 581: 2119-24. PMID 17418146 DOI: 10.1016/J.Febslet.2007.03.043  0.465
2007 Hattendorf DA, Andreeva A, Gangar A, Brennwald PJ, Weis WI. Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism. Nature. 446: 567-71. PMID 17392788 DOI: 10.1038/nature05635  0.513
2006 Wadskog I, Forsmark A, Rossi G, Konopka C, Oyen M, Goksör M, Ronne H, Brennwald P, Adler L. The yeast tumor suppressor homologue Sro7p is required for targeting of the sodium pumping ATPase to the cell surface. Molecular Biology of the Cell. 17: 4988-5003. PMID 17005914 DOI: 10.1091/Mbc.E05-08-0798  0.472
2006 Kallay LM, McNickle A, Brennwald PJ, Hubbard AL, Braiterman LT. Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains. Journal of Cellular Biochemistry. 99: 647-64. PMID 16791850 DOI: 10.1002/Jcb.20992  0.454
2006 Grosshans BL, Andreeva A, Gangar A, Niessen S, Yates JR, Brennwald P, Novick P. The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p. The Journal of Cell Biology. 172: 55-66. PMID 16390997 DOI: 10.1083/Jcb.200510016  0.74
2005 Routt SM, Ryan MM, Tyeryar K, Rizzieri KE, Mousley C, Roumanie O, Brennwald PJ, Bankaitis VA. Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast. Traffic (Copenhagen, Denmark). 6: 1157-72. PMID 16262726 DOI: 10.1111/J.1600-0854.2005.00350.X  0.639
2005 Roumanie O, Wu H, Molk JN, Rossi G, Bloom K, Brennwald P. Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex. The Journal of Cell Biology. 170: 583-94. PMID 16103227 DOI: 10.1083/Jcb.200504108  0.481
2005 Zhang X, Wang P, Gangar A, Zhang J, Brennwald P, TerBush D, Guo W. Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis. The Journal of Cell Biology. 170: 273-83. PMID 16027223 DOI: 10.1083/Jcb.200502055  0.581
2005 Gangar A, Rossi G, Andreeva A, Hales R, Brennwald P. Structurally conserved interaction of Lgl family with SNAREs is critical to their cellular function. Current Biology : Cb. 15: 1136-42. PMID 15964280 DOI: 10.1016/J.Cub.2005.05.046  0.516
2005 Brennwald P. A new function for the Elongator complex: polarization of Rab activity? Developmental Cell. 8: 454-6. PMID 15809026 DOI: 10.1016/j.devcel.2005.03.010  0.354
2005 Elbert M, Rossi G, Brennwald P. The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery. Molecular Biology of the Cell. 16: 532-49. PMID 15563607 DOI: 10.1091/mbc.E04-07-0549  0.43
2002 Müsch A, Cohen D, Yeaman C, Nelson WJ, Rodriguez-Boulan E, Brennwald PJ. Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells. Molecular Biology of the Cell. 13: 158-68. PMID 11809830 DOI: 10.1091/Mbc.01-10-0496  0.476
2001 Adamo JE, Moskow JJ, Gladfelter AS, Viterbo D, Lew DJ, Brennwald PJ. Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. The Journal of Cell Biology. 155: 581-92. PMID 11706050 DOI: 10.1083/Jcb.200106065  0.77
2001 Drees BL, Sundin B, Brazeau E, Caviston JP, Chen GC, Guo W, Kozminski KG, Lau MW, Moskow JJ, Tong A, Schenkman LR, McKenzie A, Brennwald P, Longtine M, Bi E, et al. A protein interaction map for cell polarity development. The Journal of Cell Biology. 154: 549-71. PMID 11489916 DOI: 10.1083/Jcb.200104057  0.676
2000 Katz L, Brennwald P. Testing the 3Q:1R "rule": mutational analysis of the ionic "zero" layer in the yeast exocytic SNARE complex reveals no requirement for arginine. Molecular Biology of the Cell. 11: 3849-58. PMID 11071911 DOI: 10.1091/Mbc.11.11.3849  0.722
2000 Neiman AM, Katz L, Brennwald PJ. Identification of domains required for developmentally regulated SNARE function in Saccharomyces cerevisiae Genetics. 155: 1643-1655. PMID 10924463  0.782
2000 Brennwald P. Reversal of fortune. Do Rab GTPases act on the target membrane? The Journal of Cell Biology. 149: 1-4. PMID 10747079 DOI: 10.1083/Jcb.149.1.1  0.415
2000 Brennwald P. Reversal of Fortune The Journal of Cell Biology. 149: 1-4. DOI: 10.1083/Jcb.149.1.1-A  0.397
1999 Adamo JE, Rossi G, Brennwald P. The Rho GTPase Rho3 has a direct role in exocytosis that is distinct from its role in actin polarity. Molecular Biology of the Cell. 10: 4121-33. PMID 10588647 DOI: 10.1091/Mbc.10.12.4121  0.785
1999 Lehman K, Rossi G, Adamo JE, Brennwald P. Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. The Journal of Cell Biology. 146: 125-40. PMID 10402465 DOI: 10.1083/Jcb.146.1.125  0.794
1998 Katz L, Hanson PI, Heuser JE, Brennwald P. Genetic and morphological analyses reveal a critical interaction between the C-termini of two SNARE proteins and a parallel four helical arrangement for the exocytic SNARE complex. The Embo Journal. 17: 6200-9. PMID 9799229 DOI: 10.1093/Emboj/17.21.6200  0.756
1997 Rice LM, Brennwald P, Brünger AT. Formation of a yeast SNARE complex is accompanied by significant structural changes. Febs Letters. 415: 49-55. PMID 9326367 DOI: 10.1016/S0014-5793(97)01091-0  0.482
1997 Collins RN, Brennwald P, Garrett M, Lauring A, Novick P. Interactions of nucleotide release factor Dss4p with Sec4p in the post-Golgi secretory pathway of yeast. The Journal of Biological Chemistry. 272: 18281-9. PMID 9218467 DOI: 10.1074/Jbc.272.29.18281  0.718
1997 Rossi G, Salminen A, Rice LM, Brünger AT, Brennwald P. Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C terminus of the SNAP-25 homolog, Sec9. The Journal of Biological Chemistry. 272: 16610-7. PMID 9195974 DOI: 10.1074/Jbc.272.26.16610  0.562
1995 Novick P, Garrett MD, Brennwald P, Lauring A, Finger FP, Collins R, TerBush DR. Control of exocytosis in yeast. Cold Spring Harbor Symposia On Quantitative Biology. 60: 171-7. PMID 8824389 DOI: 10.1101/Sqb.1995.060.01.020  0.478
1994 Brennwald P, Kearns B, Champion K, Keränen S, Bankaitis V, Novick P. Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis. Cell. 79: 245-58. PMID 7954793 DOI: 10.1016/0092-8674(94)90194-5  0.764
1993 Brennwald P, Novick P. Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4 Nature. 362: 560-563. PMID 8464498 DOI: 10.1038/362560A0  0.674
1993 Selinger D, Brennwald P, Liao X, Wise JA. Identification of RNA sequences and structural elements required for assembly of fission yeast SRP54 protein with signal recognition particle RNA. Molecular and Cellular Biology. 13: 1353-62. PMID 8382769 DOI: 10.1128/Mcb.13.3.1353  0.361
1993 Novick P, Brennwald P, Walworth NC, Kabcenell AK, Garrett M, Moya M, Roberts D, Müller H, Govindan B, Bowser R. The cycle of SEC4 function in vesicular transport. Ciba Foundation Symposium. 176: 218-28; discussion 2. PMID 8299422  0.693
1993 Novick P, Brennwald P. Friends and family: the role of the Rab GTPases in vesicular traffic. Cell. 75: 597-601. PMID 8242735 DOI: 10.1016/0092-8674(93)90478-9  0.548
1992 Walworth NC, Brennwald P, Kabcenell AK, Garrett M, Novick P. Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiae. Molecular and Cellular Biology. 12: 2017-28. PMID 1569938 DOI: 10.1128/Mcb.12.5.2017  0.653
1992 Jena BP, Brennwald P, Garrett MD, Novick P, Jamieson JD. Distinct and specific GAP activities in rat pancreas act on the yeast GTP-binding proteins Ypt1 and Sec4. Febs Letters. 309: 5-9. PMID 1511744 DOI: 10.1016/0014-5793(92)80727-X  0.647
1992 Novick P, Garrett MD, Brennwald P, Kabcenell AK. Purification of Sec4 protein from Saccharomyces cerevisiae and Escherichia coli. Methods in Enzymology. 219: 352-62. PMID 1488008 DOI: 10.1016/0076-6879(92)19035-5  0.656
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