Year |
Citation |
Score |
2021 |
Mishra PK, Wood H, Stanton J, Au WC, Eisenstatt JR, Boeckmann L, Sclafani RA, Weinreich M, Bloom KS, Thorpe PH, Basrai MA. Cdc7-mediated phosphorylation of Cse4 regulates high fidelity chromosome segregation in budding yeast. Molecular Biology of the Cell. mbcE21060323. PMID 34432494 DOI: 10.1091/mbc.E21-06-0323 |
0.356 |
|
2020 |
Eisenstatt JR, Boeckmann L, Au WC, Garcia V, Bursch L, Ocampo J, Costanzo M, Weinreich M, Sclafani RA, Baryshnikova A, Myers CL, Boone C, Clark DJ, Baker R, Basrai MA. Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in . G3 (Bethesda, Md.). PMID 32295767 DOI: 10.1534/G3.120.401131 |
0.47 |
|
2017 |
Sclafani RA, Hesselberth JR. O Cdc7 kinase where art thou? Current Genetics. PMID 29134273 DOI: 10.1007/S00294-017-0782-8 |
0.513 |
|
2017 |
Rossbach D, Bryan DS, Hesselberth JR, Sclafani R. Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae. G3 (Bethesda, Md.). PMID 28924058 DOI: 10.1534/G3.117.300223 |
0.781 |
|
2017 |
Todd MC, Langan TA, Sclafani RA. Doxycycline-Regulated p16(MTS1) Expression Suppresses the Anchorage-Independence and Tumorigenicity of Breast Cancer Cell Lines that Lack Endogenous p16. Journal of Cancer. 8: 190-198. PMID 28243323 DOI: 10.7150/Jca.15481 |
0.791 |
|
2015 |
Shrotriya S, Agarwal R, Sclafani RA. A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma. Advances in Experimental Medicine and Biology. 815: 333-48. PMID 25427916 DOI: 10.1007/978-3-319-09614-8_19 |
0.38 |
|
2014 |
Ramey CJ, Sclafani RA. Functional conservation of the pre-sensor one beta-finger hairpin (PS1-hp) structures in mini-chromosome maintenance proteins of Saccharomyces cerevisiae and archaea. G3 (Bethesda, Md.). 4: 1319-26. PMID 24875627 DOI: 10.1534/G3.114.011668 |
0.779 |
|
2014 |
Brandão LN, Ferguson R, Santoro I, Jinks-Robertson S, Sclafani RA. The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae. Genetics. 197: 1111-22. PMID 24875188 DOI: 10.1534/Genetics.114.165308 |
0.759 |
|
2014 |
Sclafani R, Agarwal R, Tyagi A, Siriwardana S, Takahata T, Frederick B, Raben D. Chemoprevention by Resveratrol in Head-and-Neck Cancer International Journal of Radiation Oncology*Biology*Physics. 88: 512. DOI: 10.1016/J.Ijrobp.2013.11.154 |
0.587 |
|
2013 |
Zhong Y, Nellimoottil T, Peace JM, Knott SR, Villwock SK, Yee JM, Jancuska JM, Rege S, Tecklenburg M, Sclafani RA, Tavaré S, Aparicio OM. The level of origin firing inversely affects the rate of replication fork progression. The Journal of Cell Biology. 201: 373-83. PMID 23629964 DOI: 10.1083/Jcb.201208060 |
0.501 |
|
2012 |
Han KJ, Foster DG, Zhang NY, Kanisha K, Dzieciatkowska M, Sclafani RA, Hansen KC, Peng J, Liu CW. Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron. The Journal of Biological Chemistry. 287: 43741-52. PMID 23112048 DOI: 10.1074/Jbc.M112.372318 |
0.345 |
|
2012 |
Bahmed K, Henry C, Holliday M, Redzic J, Ciobanu M, Zhang F, Weekes C, Sclafani R, Degregori J, Eisenmesser E. Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B. Cancer Cell International. 12: 19. PMID 22631225 DOI: 10.1186/1475-2867-12-19 |
0.328 |
|
2011 |
Tyagi A, Gu M, Takahata T, Frederick B, Agarwal C, Siriwardana S, Agarwal R, Sclafani RA. Resveratrol selectively induces DNA Damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 5402-11. PMID 21705453 DOI: 10.1158/1078-0432.Ccr-11-1072 |
0.643 |
|
2011 |
Radhakrishnan S, Reddivari L, Sclafani R, Das UN, Vanamala J. Resveratrol potentiates grape seed extract induced human colon cancer cell apoptosis. Frontiers in Bioscience (Elite Edition). 3: 1509-23. PMID 21622155 DOI: 10.2741/E352 |
0.309 |
|
2011 |
Kaur M, Tyagi A, Singh RP, Sclafani RA, Agarwal R, Agarwal C. Grape seed extract upregulates p21 (Cip1) through redox-mediated activation of ERK1/2 and posttranscriptional regulation leading to cell cycle arrest in colon carcinoma HT29 cells. Molecular Carcinogenesis. 50: 553-62. PMID 21268136 DOI: 10.1002/Mc.20739 |
0.453 |
|
2011 |
Tyagi A, Gu M, Fredrick B, Agarwal C, Siriwardana S, Agarwal R, Sclafani RA. Abstract 3708: Resveratrol induces DNA damage independent of Smad4 expression in its efficacy against human head and neck carcinoma cells Cancer Research. 71: 3708-3708. DOI: 10.1158/1538-7445.Am2011-3708 |
0.407 |
|
2010 |
Holzen TM, Sclafani R. Genetic interaction of RAD53 protein kinase with histones is important for DNA replication. Cell Cycle (Georgetown, Tex.). 9: 4735-47. PMID 21099362 DOI: 10.4161/Cc.9.23.14091 |
0.817 |
|
2009 |
Chien CY, Chen BR, Chou CK, Sclafani RA, Su JY. The yeast Cdc8 exhibits both deoxythymidine monophosphate and diphosphate kinase activities. Febs Letters. 583: 2281-6. PMID 19540237 DOI: 10.1016/J.Febslet.2009.06.022 |
0.821 |
|
2009 |
Roy S, Gu M, Ramasamy K, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. p21/Cip1 and p27/Kip1 Are essential molecular targets of inositol hexaphosphate for its antitumor efficacy against prostate cancer. Cancer Research. 69: 1166-73. PMID 19176374 DOI: 10.1158/0008-5472.Can-08-3115 |
0.362 |
|
2008 |
Leon RP, Tecklenburg M, Sclafani RA. Functional conservation of beta-hairpin DNA binding domains in the Mcm protein of Methanobacterium thermoautotrophicum and the Mcm5 protein of Saccharomyces cerevisiae. Genetics. 179: 1757-68. PMID 18660534 DOI: 10.1534/Genetics.108.088690 |
0.811 |
|
2008 |
Roy S, Singh RP, Agarwal C, Siriwardana S, Sclafani R, Agarwal R. Downregulation of both p21/Cip1 and p27/Kip1 produces a more aggressive prostate cancer phenotype. Cell Cycle (Georgetown, Tex.). 7: 1828-35. PMID 18583941 DOI: 10.4161/Cc.7.12.6024 |
0.326 |
|
2008 |
Sclafani RA, Holzen TM. Cell cycle regulation of DNA replication. Annual Review of Genetics. 41: 237-80. PMID 17630848 DOI: 10.1146/Annurev.Genet.41.110306.130308 |
0.824 |
|
2007 |
Roy S, Kaur M, Agarwal C, Tecklenburg M, Sclafani RA, Agarwal R. p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells. Molecular Cancer Therapeutics. 6: 2696-707. PMID 17938263 DOI: 10.1158/1535-7163.Mct-07-0104 |
0.386 |
|
2007 |
Hoang ML, Leon RP, Pessoa-Brandao L, Hunt S, Raghuraman MK, Fangman WL, Brewer BJ, Sclafani RA. Structural changes in Mcm5 protein bypass Cdc7-Dbf4 function and reduce replication origin efficiency in Saccharomyces cerevisiae. Molecular and Cellular Biology. 27: 7594-602. PMID 17724082 DOI: 10.1128/Mcb.00997-07 |
0.748 |
|
2006 |
Dohrmann PR, Sclafani RA. Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae. Genetics. 174: 87-99. PMID 16816422 DOI: 10.1534/Genetics.106.060236 |
0.841 |
|
2005 |
Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells. Carcinogenesis. 26: 1978-87. PMID 15975956 DOI: 10.1093/Carcin/Bgi165 |
0.509 |
|
2004 |
Pessoa-Brandão L, Sclafani RA. CDC7/DBF4 functions in the translesion synthesis branch of the RAD6 epistasis group in Saccharomyces cerevisiae. Genetics. 167: 1597-610. PMID 15342501 DOI: 10.1534/Genetics.103.021675 |
0.808 |
|
2004 |
Sclafani RA, Fletcher RJ, Chen XS. Two heads are better than one: regulation of DNA replication by hexameric helicases. Genes & Development. 18: 2039-45. PMID 15342486 DOI: 10.1101/Gad.1240604 |
0.464 |
|
2003 |
Agarwal C, Singh RP, Dhanalakshmi S, Tyagi AK, Tecklenburg M, Sclafani RA, Agarwal R. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene. 22: 8271-82. PMID 14614451 DOI: 10.1038/Sj.Onc.1207158 |
0.419 |
|
2003 |
Limesand KH, Barzen KA, Sanders LA, Sclafani RA, Raynolds MV, Reyland ME, Anderson SM, Quissell DO. Characterization of rat parotid and submandibular acinar cell apoptosis in primary culture. In Vitro Cellular & Developmental Biology. Animal. 39: 170-7. PMID 14505429 DOI: 10.1007/S11626-003-0012-1 |
0.397 |
|
2003 |
Fletcher RJ, Bishop BE, Leon RP, Sclafani RA, Ogata CM, Chen XS. The structure and function of MCM from archaeal M. Thermoautotrophicum. Nature Structural Biology. 10: 160-7. PMID 12548282 DOI: 10.1038/Nsb893 |
0.815 |
|
2002 |
Sclafani RA, Tecklenburg M, Pierce A. The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae. Genetics. 161: 47-57. PMID 12019222 |
0.731 |
|
2002 |
Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM. Corrigendum to “Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells” Cancer Letters. 180: 223. DOI: 10.1016/S0304-3835(02)00016-2 |
0.322 |
|
2001 |
Fouty BW, Grimison B, Fagan KA, Le Cras TD, Harral JW, Hoedt-Miller M, Sclafani RA, Rodman DM. p27(Kip1) is important in modulating pulmonary artery smooth muscle cell proliferation. American Journal of Respiratory Cell and Molecular Biology. 25: 652-8. PMID 11713109 DOI: 10.1165/Ajrcmb.25.5.4592 |
0.796 |
|
2001 |
Mamay CL, Schauer IE, Rice PL, McDoniels-Silvers A, Dwyer-Nield LD, You M, Sclafani RA, Malkinson AM. Cyclin D1 as a proliferative marker regulating retinoblastoma phosphorylation in mouse lung epithelial cells. Cancer Letters. 168: 165-72. PMID 11403921 DOI: 10.1016/S0304-3835(01)00480-3 |
0.377 |
|
2000 |
Grimison B, Langan TA, Sclafani RA. P16Ink4a tumor suppressor function in lung cancer cells involves cyclin-dependent kinase 2 inhibition by Cip/Kip protein redistribution. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 11: 507-15. PMID 11063124 |
0.81 |
|
2000 |
Todd MC, Sclafani RA, Langan TA. Ovarian cancer cells that coexpress endogenous Rb and p16 are insensitive to overexpression of functional p16 protein. Oncogene. 19: 258-64. PMID 10645004 DOI: 10.1038/Sj.Onc.1203289 |
0.786 |
|
2000 |
Desai A, Holleran EA, Roche S, Servant G, Weiner O, Aasland R, Weinzierl RO, Ponnambalam V, Slesinger PA, Pfaff M, Schuldt A, Kudoh T, Sclafani RA. Cell biology Current Opinion in Cell Biology. 12: 265-275. DOI: 10.1016/S0955-0674(00)00086-7 |
0.321 |
|
1999 |
Oshiro G, Owens JC, Shellman Y, Sclafani RA, Li JJ. Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability. Molecular and Cellular Biology. 19: 4888-96. PMID 10373538 DOI: 10.1128/Mcb.19.7.4888 |
0.761 |
|
1999 |
Shellman YG, Svee E, Sclafani RA, Langan TA. Identification and characterization of individual cyclin-dependent kinase complexes from Saccharomyces cerevisiae. Yeast (Chichester, England). 15: 295-309. PMID 10206189 DOI: 10.1002/(Sici)1097-0061(19990315)15:4<295::Aid-Yea377>3.0.Co;2-Z |
0.805 |
|
1998 |
Sclafani RA. Chromosomes in the Rocky Mountains. Yeast chromosome structure, replication and segregation, Snowmass, CO, USA, 8-13 August 1998. Trends in Genetics : Tig. 14: 441-2. PMID 9825670 DOI: 10.1016/S0168-9525(98)01610-2 |
0.305 |
|
1998 |
Shellman YG, Schauer IE, Oshiro G, Dohrmann P, Sclafani RA. Oligomers of the Cdc7/Dbf4 protein kinase exist in the yeast cell. Molecular & General Genetics : Mgg. 259: 429-36. PMID 9790600 DOI: 10.1007/S004380050833 |
0.821 |
|
1998 |
Hess GF, Drong RF, Weiland KL, Slightom JL, Sclafani RA, Hollingsworth RE. A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines. Gene. 211: 133-40. PMID 9573348 DOI: 10.1016/S0378-1119(98)00094-8 |
0.47 |
|
1997 |
Hovland PG, Tecklenberg M, Sclafani RA. Overexpression of the protein kinase Pak1 suppresses yeast DNA polymerase mutations. Molecular & General Genetics : Mgg. 256: 45-53. PMID 9341678 DOI: 10.1007/S004380050544 |
0.542 |
|
1997 |
Groshong SD, Owen GI, Grimison B, Schauer IE, Todd MC, Langan TA, Sclafani RA, Lange CA, Horwitz KB. Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1). Molecular Endocrinology (Baltimore, Md.). 11: 1593-607. PMID 9328342 DOI: 10.1210/Mend.11.11.0006 |
0.772 |
|
1997 |
Hardy CF, Dryga O, Seematter S, Pahl PM, Sclafani RA. mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p. Proceedings of the National Academy of Sciences of the United States of America. 94: 3151-5. PMID 9096361 DOI: 10.1073/Pnas.94.7.3151 |
0.532 |
|
1997 |
Sclafani RA. Cyclin dependent kinase activating kinases. Current Opinion in Cell Biology. 8: 788-94. PMID 8939668 DOI: 10.1016/S0955-0674(96)80079-2 |
0.496 |
|
1997 |
Sclafani R, Schauer I, Dalton M, Grimison B, Langan T. 591 Mechanism of the altered regulation of the G1 to S phase transition of the cell cycle in lung cancer cells Lung Cancer. 18: 152. DOI: 10.1016/s0169-5002(97)89971-0 |
0.648 |
|
1995 |
Ostroff RM, Sclafani RA. Cell cycle regulation of induced mutagenesis in yeast. Mutation Research. 329: 143-52. PMID 7603496 DOI: 10.1016/0027-5107(95)00030-M |
0.558 |
|
1994 |
Schauer IE, Siriwardana S, Langan TA, Sclafani RA. Cyclin D1 overexpression vs. retinoblastoma inactivation: implications for growth control evasion in non-small cell and small cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 91: 7827-31. PMID 8052667 DOI: 10.1073/Pnas.91.16.7827 |
0.679 |
|
1994 |
Sclafani RA, Jackson AL. Cdc7 protein kinase for DNA metabolism comes of age. Molecular Microbiology. 11: 805-10. PMID 8022258 DOI: 10.1111/J.1365-2958.1994.Tb00358.X |
0.569 |
|
1994 |
Sclafani R, Schauer I, Siriwardana S, Langan T. Cyclin D1 overexpression vs. RB inactivation: Alternate mechanisms of growth control evasion in non small cell (NSCLC) and small cell lung cancer (SCLC)? Lung Cancer. 11: 8. DOI: 10.1016/0169-5002(94)93801-6 |
0.622 |
|
1993 |
Jackson AL, Pahl PM, Harrison K, Rosamond J, Sclafani RA. Cell cycle regulation of the yeast Cdc7 protein kinase by association with the Dbf4 protein. Molecular and Cellular Biology. 13: 2899-908. PMID 8474449 DOI: 10.1128/Mcb.13.5.2899 |
0.58 |
|
1993 |
Hollingsworth RE, Sclafani RA. Yeast pre-meiotic DNA replication utilizes mitotic origin ARS1 independently of CDC7 function. Chromosoma. 102: 415-20. PMID 8365350 DOI: 10.1007/Bf00360406 |
0.505 |
|
1991 |
Su JY, Sclafani RA. Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast. Nucleic Acids Research. 19: 823-7. PMID 2017365 DOI: 10.1093/Nar/19.4.823 |
0.464 |
|
1990 |
Hollingsworth RE, Sclafani RA. DNA metabolism gene CDC7 from yeast encodes a serine (threonine) protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 87: 6272-6. PMID 2166954 DOI: 10.1073/Pnas.87.16.6272 |
0.579 |
|
1989 |
Langan TA, Gautier J, Lohka M, Hollingsworth R, Moreno S, Nurse P, Maller J, Sclafani RA. Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells. Molecular and Cellular Biology. 9: 3860-8. PMID 2550805 DOI: 10.1128/Mcb.9.9.3860 |
0.815 |
|
1989 |
Hovland P, Flick J, Johnston M, Sclafani RA. Galactose as a gratuitous inducer of GAL gene expression in yeasts growing on glucose. Gene. 83: 57-64. PMID 2512199 DOI: 10.1016/0378-1119(89)90403-4 |
0.769 |
|
1988 |
Sclafani RA, Patterson M, Rosamond J, Fangman WL. Differential regulation of the yeast CDC7 gene during mitosis and meiosis. Molecular and Cellular Biology. 8: 293-300. PMID 3275871 DOI: 10.1128/Mcb.8.1.293 |
0.718 |
|
1987 |
Patterson M, Sclafani RA, Fangman WL, Rosamond J. Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae. Molecular and Cellular Biology. 6: 1590-8. PMID 3537706 DOI: 10.1128/Mcb.6.5.1590 |
0.722 |
|
1984 |
Sclafani RA, Fangman WL. Conservative replication of double-stranded RNA in Saccharomyces cerevisiae by displacement of progeny single strands. Molecular and Cellular Biology. 4: 1618-26. PMID 6387443 DOI: 10.1128/MCB.4.8.1618 |
0.621 |
|
1984 |
Sclafani RA, Fangman WL. Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK. Proceedings of the National Academy of Sciences of the United States of America. 81: 5821-5. PMID 6091111 DOI: 10.1073/pnas.81.18.5821 |
0.716 |
|
1982 |
Sclafani RA, Wechsler JA. High-yield purification of small, single-stranded DNA. Analytical Biochemistry. 115: 197-202. PMID 7030125 DOI: 10.1016/0003-2697(81)90546-7 |
0.343 |
|
1981 |
Sclafani RA, Wechsler JA. Growth of phages lambda and phiX174 under Plban protein control in the absence of host dnaB function. Virology. 113: 314-22. PMID 6267785 DOI: 10.1016/0042-6822(81)90158-6 |
0.349 |
|
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