Martine F. Roussel - Publications

Affiliations: 
University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Molecular Biology, Cell Biology, Oncology

134 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Smith KS, Xu K, Mercer KS, Boop F, Klimo P, DeCupyere M, Grenet J, Robinson S, Dunphy P, Baker SJ, Ellison DW, Merchant TE, Upadayaya SA, Gajjar A, Wu G, ... ... Roussel MF, et al. Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource. Acta Neuropathologica. PMID 32519082 DOI: 10.1007/S00401-020-02171-5  0.307
2020 Wijaya J, Vo BT, Liu J, Xu B, Wu G, Wang Y, Peng J, Zhang J, Janke LJ, Orr BA, Yu J, Roussel MF, Schuetz JD. An ABC transporter drives medulloblastoma pathogenesis by regulating Sonic Hedgehog signaling. Cancer Research. PMID 31948942 DOI: 10.1158/0008-5472.Can-19-2054  0.371
2020 Dunphy PS, Xu K, Gentry DT, He C, Mercer K, Zhu X, Smith K, Gudenas B, Robinson S, Zhang J, Kasper LH, Kwon C, Hover LD, Larson JD, Twarog N, ... ... Roussel MF, et al. Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors Tumor Biology. DOI: 10.1158/1538-7445.Am2020-6144  0.301
2019 Campagne O, Davis A, Maharaj AR, Zhong B, Stripay J, Farmer D, Roussel MF, Stewart CF. CNS penetration and pharmacodynamics of the CHK1 inhibitor prexasertib in a mouse Group 3 medulloblastoma model. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105106. PMID 31669383 DOI: 10.1016/J.Ejps.2019.105106  0.338
2019 Zhang L, He X, Liu X, Zhang F, Huang LF, Potter AS, Xu L, Zhou W, Zheng T, Luo Z, Berry KP, Pribnow A, Smith SM, Fuller C, Jones BV, ... ... Roussel MF, et al. Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. Cancer Cell. PMID 31474569 DOI: 10.1016/J.Ccell.2019.07.009  0.367
2019 Annunziata I, van de Vlekkert D, Wolf E, Finkelstein D, Neale G, Machado E, Mosca R, Campos Y, Tillman H, Roussel MF, Andrew Weesner J, Ellen Fremuth L, Qiu X, Han MJ, Grosveld GC, et al. MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat. Nature Communications. 10: 3623. PMID 31399583 DOI: 10.1038/S41467-019-11568-0  0.324
2019 Wang J, Merino DM, Light N, Murphy BL, Wang YD, Guo X, Hodges AP, Chau LQ, Liu KW, Dhall G, Asgharzadeh S, Kiehna EN, Shirey RJ, Janda KD, Taylor MD, ... ... Roussel MF, et al. Myc and loss of p53 cooperate to drive formation of choroid plexus carcinoma. Cancer Research. PMID 30885981 DOI: 10.1158/0008-5472.Can-18-2565  0.382
2019 Jonchere B, Stripay J, Pribnow A, Zindy F, Min J, Freeman B, Shelat A, Rankovic Z, Roussel M. PDTM-02. TARGETING THE RB PATHWAY IN MEDULLOBLASTOMA Neuro-Oncology. 21: vi187-vi187. DOI: 10.1093/Neuonc/Noz175.778  0.323
2018 Vo BT, Kwon JA, Li C, Finkelstein D, Xu B, Orr BA, Sherr CJ, Roussel MF. Mouse medulloblastoma driven by CRISPR activation of cellular Myc. Scientific Reports. 8: 8733. PMID 29880921 DOI: 10.1038/S41598-018-24956-1  0.364
2018 Ganguly D, Fan M, Yang CH, Zbytek B, Finkelstein D, Roussel MF, Pfeffer LM. The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma. Oncotarget. 9: 22095-22112. PMID 29774125 DOI: 10.18632/Oncotarget.25188  0.388
2018 El Nagar S, Zindy F, Moens C, Martin L, Plassard D, Roussel MF, Lamonerie T, Billon N. A new genetically engineered mouse model of choroid plexus carcinoma. Biochemical and Biophysical Research Communications. PMID 29339161 DOI: 10.1016/J.Bbrc.2017.11.192  0.332
2018 Zuckermann M, Ismer B, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Roussel MF, Reifenberger G, Lichter P, Pfister SM, Kawauchi D, Gronych J, Jones DT. Abstract 5109: Somatic CRISPR/Cas9-mediated gene editing enables versatile brain tumor modeling Cancer Research. 78: 5109-5109. DOI: 10.1158/1538-7445.Am2018-5109  0.361
2017 Roussel MF, Stripay JL. Epigenetic Drivers in Pediatric Medulloblastoma. Cerebellum (London, England). PMID 29178021 DOI: 10.1007/S12311-017-0899-9  0.314
2017 Wei L, Murphy BL, Wu G, Parker M, Easton J, Gilbertson RJ, Zhang J, Roussel MF. Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors. Oncotarget. 8: 64685-64697. PMID 29029386 DOI: 10.18632/Oncotarget.19642  0.352
2017 Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD. Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. Jci Insight. 2. PMID 28768907 DOI: 10.1172/Jci.Insight.92409  0.315
2017 Kawauchi D, Ogg RJ, Liu L, Shih DJH, Finkelstein D, Murphy BL, Rehg JE, Korshunov A, Calabrese C, Zindy F, Phoenix T, Kawaguchi Y, Gronych J, Gilbertson RJ, Lichter P, ... ... Roussel MF, et al. Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells. Oncogene. PMID 28504719 DOI: 10.1038/Onc.2017.110  0.373
2017 Vo BT, Li C, Morgan MA, Theurillat I, Finkelstein D, Wright S, Hyle J, Smith SM, Fan Y, Wang YD, Wu G, Orr BA, Northcott PA, Shilatifard A, Sherr CJ, ... Roussel MF, et al. Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma. Cell Reports. 18: 2907-2917. PMID 28329683 DOI: 10.1016/J.Celrep.2017.02.073  0.357
2017 Jones Z, Roberts J, Houke H, Roussel M, Stewart C, Panetta C. Abstract 314: Evaluation of effective drug combinations of sonidegib and ribociclib for treatment of Sonic hedgehog medulloblastoma using mathematical models of the cell cycle and Hedgehog pathways Cancer Research. 77: 314-314. DOI: 10.1158/1538-7445.Am2017-314  0.333
2016 Phoenix TN, Patmore DM, Boop S, Boulos N, Jacus MO, Patel YT, Roussel MF, Finkelstein D, Goumnerova L, Perreault S, Wadhwa E, Cho YJ, Stewart CF, Gilbertson RJ. Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype. Cancer Cell. PMID 27050100 DOI: 10.1016/J.Ccell.2016.03.002  0.317
2016 Vo BT, Wolf E, Kawauchi D, Gebhardt A, Rehg JE, Finkelstein D, Walz S, Murphy BL, Youn YH, Han YG, Eilers M, Roussel MF. The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity. Cancer Cell. 29: 5-16. PMID 26766587 DOI: 10.1016/J.Ccell.2015.12.003  0.305
2016 Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DT, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, et al. PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING Neuro-Oncology. 18: iii142.2-iii142. DOI: 10.1093/Neuonc/Now080.15  0.311
2015 Morfouace M, Nimmervoll B, Boulos N, Patel YT, Shelat A, Freeman BB, Robinson GW, Wright K, Gajjar A, Stewart CF, Gilbertson RJ, Roussel MF. Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors. Journal of Neuro-Oncology. PMID 26518542 DOI: 10.1007/S11060-015-1965-0  0.328
2015 Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DT, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, et al. Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling. Nature Communications. 6: 7391. PMID 26067104 DOI: 10.1038/Ncomms8391  0.304
2015 Penas C, Govek EE, Fang Y, Ramachandran V, Daniel M, Wang W, Maloof ME, Rahaim RJ, Bibian M, Kawauchi D, Finkelstein D, Han JL, Long J, Li B, Robbins DJ, ... ... Roussel MF, et al. Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. Cell Reports. 11: 249-60. PMID 25843713 DOI: 10.1016/J.Celrep.2015.03.016  0.349
2015 Zuckermann M, Hovestadt V, Knobbe-Thomsen CB, Zapatka M, Northcott PA, Schramm K, Belic J, Jones DTW, Tschida B, Moriarity B, Largaespada D, Roussel MF, Korshunov A, Reifenberger G, Pfister SM, et al. Abstract PR02: Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling Brain. 75. DOI: 10.1158/1538-7445.Brain15-Pr02  0.367
2015 Morfouace M, Patel Y, Shelat A, Kawauchi D, Robinson GW, Guy K, Gilbertson RJ, Stewart C, Gajjar A, Roussel MF. Abstract IA21: Pediatric medulloblastoma: Drug screens and preclinical studies Brain. 75. DOI: 10.1158/1538-7445.Brain15-Ia21  0.348
2014 Lindsey JC, Kawauchi D, Schwalbe EC, Solecki DJ, Selby MP, McKinnon PJ, Olson JM, Hayden JT, Grundy RG, Ellison DW, Williamson D, Bailey S, Roussel MF, Clifford SC. Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance. Oncogene. PMID 25531316 DOI: 10.1038/Onc.2014.405  0.33
2014 Cox BC, Dearman JA, Brancheck J, Zindy F, Roussel MF, Zuo J. Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear. Scientific Reports. 4: 6885. PMID 25363458 DOI: 10.1038/Srep06885  0.334
2014 Doherty JR, Nilsson LM, Kuliyev E, Zhu H, Matthew R, Cleveland JL, Mead PE, Roussel MF. Embryonic Expression and Function of the Xenopus Ink4d Cyclin D-Dependent Kinase Inhibitor. Cell & Developmental Biology. 3. PMID 25309971 DOI: 10.4172/2168-9296.1000133  0.354
2014 Vo BT, Wolf E, Kawauchi D, Rehg J, Finkelstein D, Murphy B, Eilers M, Roussel MF. Abstract 2977: Myc and Miz1 in medulloblastoma Cancer Research. 74: 2977-2977. DOI: 10.1158/1538-7445.Am2014-2977  0.353
2014 Wei L, Murphy BL, Parker M, Wu G, Easton J, Roussel MF, Zhang J. Ge-40Comparative Genomic Analyses Identifies Non-Silent Mutations Present In Both Murine And Human Medulloblastoma Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou256.39  0.34
2014 Penas C, Zhang M, Clarke J, Stathias V, Roussel M, Hatten M, Ayad N. Cb-14Genomic Approaches To Identify Coding And Noncoding Rna Targets In Medulloblastoma. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou241.13  0.359
2013 Anne SL, Govek EE, Ayrault O, Kim JH, Zhu X, Murphy DA, Van Aelst L, Roussel MF, Hatten ME. WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. Plos One. 8: e81769. PMID 24303070 DOI: 10.1371/Journal.Pone.0081769  0.346
2013 Roussel MF, Robinson GW. Role of MYC in Medulloblastoma. Cold Spring Harbor Perspectives in Medicine. 3. PMID 24186490 DOI: 10.1101/Cshperspect.A014308  0.343
2013 Wolf E, Gebhardt A, Kawauchi D, Walz S, von Eyss B, Wagner N, Renninger C, Krohne G, Asan E, Roussel MF, Eilers M. Miz1 is required to maintain autophagic flux. Nature Communications. 4: 2535. PMID 24088869 DOI: 10.1038/Ncomms3535  0.364
2013 Zhao M, Gupta V, Raj L, Roussel M, Bei M. A Network of Transcription Factors Operates during Early Tooth Morphogenesis Molecular and Cellular Biology. 33: 3099-3112. PMID 23754753 DOI: 10.1128/Mcb.00524-13  0.314
2013 Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng FY, Shelat AA, Guy K, Taylor MR, Chen T, Roussel MF. Identification of small molecule activators of BMP signaling. Plos One. 8: e59045. PMID 23527084 DOI: 10.1371/Journal.Pone.0059045  0.305
2013 Turner DC, Freeman BB, Jacus MO, Morfouace M, Throm SL, Vuppala PK, Roussel M, Gajjar A, Stewart CF. Abstract 2749: Gemcitabine (GEM), a drug with clinical activity against pediatric solid tumors, demonstrates satisfactory CNS penetration in a preclinical murine medulloblastoma (MB) model. Cancer Research. 73: 2749-2749. DOI: 10.1158/1538-7445.Am2013-2749  0.304
2012 Liu Z, Dearman JA, Cox BC, Walters BJ, Zhang L, Ayrault O, Zindy F, Gan L, Roussel MF, Zuo J. Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6600-10. PMID 22573682 DOI: 10.1523/Jneurosci.0818-12.2012  0.314
2012 Kawauchi D, Robinson G, Uziel T, Gibson P, Rehg J, Gao C, Finkelstein D, Qu C, Pounds S, Ellison DW, Gilbertson RJ, Roussel MF. A mouse model of the most aggressive subgroup of human medulloblastoma. Cancer Cell. 21: 168-80. PMID 22340591 DOI: 10.1016/J.Ccr.2011.12.023  0.361
2012 Kawauchi D, Robinson G, Uziel T, Elisson DW, Gilbertson RJ, Roussel MF. Abstract SY10-03: Cell of origin in pediatric medulloblastomas Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy10-03  0.363
2012 Kawauchi D, Robinson G, Uziel T, Gibson P, Rehg J, Gao C, Finkelstein D, Qu C, Pounds S, Ellison DW, Gilbertson RJ, Roussel MF. Abstract 1434: A mouse model of the most aggressive subgroup of human medulloblastoma Cancer Research. 72: 1434-1434. DOI: 10.1158/1538-7445.Am2012-1434  0.378
2011 Gil-Perotin S, Haines JD, Kaur J, Marin-Husstege M, Spinetta MJ, Kim KH, Duran-Moreno M, Schallert T, Zindy F, Roussel MF, Garcia-Verdugo JM, Casaccia P. Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone. The European Journal of Neuroscience. 34: 1040-52. PMID 21899604 DOI: 10.1111/J.1460-9568.2011.07836.X  0.408
2011 Wang Y, Fisher JC, Mathew R, Ou L, Otieno S, Sublet J, Xiao L, Chen J, Roussel MF, Kriwacki RW. Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21. Nature Chemical Biology. 7: 214-21. PMID 21358637 DOI: 10.1038/Nchembio.536  0.318
2011 Hatten ME, Roussel MF. Development and cancer of the cerebellum. Trends in Neurosciences. 34: 134-42. PMID 21315459 DOI: 10.1016/J.Tins.2011.01.002  0.333
2011 Roussel MF, Hatten ME. Cerebellum development and medulloblastoma. Current Topics in Developmental Biology. 94: 235-82. PMID 21295689 DOI: 10.1016/B978-0-12-380916-2.00008-5  0.323
2011 Trikha P, Sharma N, Opavsky R, Reyes A, Pena C, Ostrowski MC, Roussel MF, Leone G. E2f1-3 are critical for myeloid development. The Journal of Biological Chemistry. 286: 4783-95. PMID 21115501 DOI: 10.1074/Jbc.M110.182733  0.359
2011 Roussel M. p27(Kip1) enforces maintenance of quiescence in the mammalian ear and the pituitary gland. Cell Cycle. 10: 2617-2618. DOI: 10.4161/Cc.10.16.16544  0.325
2011 Vrijens K, Lin W, Cui J, Shelat A, Taylor M, Guy KR, Chen T, Roussel MF. Abstract 4522: Identification of small molecule agonists/activators of BMP-2, 4, 7 signaling Cancer Research. 71: 4522-4522. DOI: 10.1158/1538-7445.Am2011-4522  0.341
2011 Lindsey JC, Schwalbe EC, Kawauchi D, Olson JM, McKinnon PJ, Gilbertson RJ, Roussel MF, Ellison DW, Bailey S, Clifford SC. Abstract 3449: Epigenomics identifies conserved DNA methylation events associated with medulloblastoma development in humans and mice Cancer Research. 71: 3449-3449. DOI: 10.1158/1538-7445.Am2011-3449  0.328
2011 Gibson P, Tong Y, Robinson G, Poppleton H, Thompson MC, Currle DS, Eden C, Hogg TL, Finkelstein D, Pounds S, Patay Z, Scoggins M, Pei Y, Ogg R, Lee Y, ... ... Roussel MF, et al. Abstract 3448: Subtypes of medulloblastoma have distinct developmental origins Cancer Research. 71: 3448-3448. DOI: 10.1158/1538-7445.Am2011-3448  0.373
2011 Kawauchi D, Robinson G, Uziel T, Rehg J, Zindy F, Qu C, Gajjar A, Gilbertson RJ, Roussel MF. Abstract 3444: Enforced expression of MycN and C-Myc induces different medulloblastoma subtypes Cancer Research. 71: 3444-3444. DOI: 10.1158/1538-7445.Am2011-3444  0.374
2010 Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, ... ... Roussel MF, et al. Subtypes of medulloblastoma have distinct developmental origins. Nature. 468: 1095-9. PMID 21150899 DOI: 10.1038/Nature09587  0.335
2010 Roussel MF. New concepts in organ site research on medulloblastoma: genetics and genomics. Future Oncology (London, England). 6: 1229-31. PMID 20799868 DOI: 10.2217/Fon.10.86  0.323
2010 Ayrault O, Zhao H, Zindy F, Qu C, Sherr CJ, Roussel MF. Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells. Cancer Research. 70: 5618-27. PMID 20516124 DOI: 10.1158/0008-5472.Can-09-3740  0.363
2009 Ayrault O, Godeny MD, Dillon C, Zindy F, Fitzgerald P, Roussel MF, Beere HM. Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma. Proceedings of the National Academy of Sciences of the United States of America. 106: 17037-42. PMID 19805107 DOI: 10.1073/Pnas.0902880106  0.415
2009 Ayrault O, Zindy F, Rehg J, Sherr CJ, Roussel MF. Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma. Molecular Cancer Research : McR. 7: 33-40. PMID 19147535 DOI: 10.1158/1541-7786.Mcr-08-0369  0.414
2008 Forget A, Ayrault O, den Besten W, Kuo ML, Sherr CJ, Roussel MF. Differential post-transcriptional regulation of two Ink4 proteins, p18 Ink4c and p19 Ink4d. Cell Cycle (Georgetown, Tex.). 7: 3737-46. PMID 19029828 DOI: 10.4161/Cc.7.23.7187  0.383
2008 Reilly KM, Rubin JB, Gilbertson RJ, Garbow JR, Roussel MF, Gutmann DH. Rethinking brain tumors: the fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop. Cancer Research. 68: 5508-11. PMID 18632599 DOI: 10.1158/0008-5472.Can-08-0703  0.361
2008 Zhao H, Ayrault O, Zindy F, Kim JH, Roussel MF. Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development. Genes & Development. 22: 722-7. PMID 18347090 DOI: 10.1101/Gad.1636408  0.347
2007 Zindy F, Uziel T, Ayrault O, Calabrese C, Valentine M, Rehg JE, Gilbertson RJ, Sherr CJ, Roussel MF. Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors. Cancer Research. 67: 2676-84. PMID 17363588 DOI: 10.1158/0008-5472.Can-06-3418  0.4
2007 Laine H, Doetzlhofer A, Mantela J, Ylikoski J, Laiho M, Roussel MF, Segil N, Pirvola U. p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1434-44. PMID 17287518 DOI: 10.1523/Jneurosci.4956-06.2007  0.375
2007 Nilsson LM, Keller UB, Yang C, Nilsson JA, Cleveland JL, Roussel MF. Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis Oncogene. 26: 2833-2839. PMID 17099725 DOI: 10.1038/Sj.Onc.1210104  0.371
2006 Williams RT, Roussel MF, Sherr CJ. Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 103: 6688-93. PMID 16618932 DOI: 10.1073/Pnas.0602030103  0.388
2006 Uziel T, Zindy F, Sherr CJ, Roussel MF. The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma. Cell Cycle (Georgetown, Tex.). 5: 363-5. PMID 16479172 DOI: 10.4161/Cc.5.4.2475  0.463
2006 Gil-Perotin S, Marin-Husstege M, Li J, Soriano-Navarro M, Zindy F, Roussel MF, Garcia-Verdugo JM, Casaccia-Bonnefil P. Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1107-16. PMID 16436596 DOI: 10.1523/Jneurosci.3970-05.2006  0.414
2005 Sherr CJ, Bertwistle D, DEN Besten W, Kuo ML, Sugimoto M, Tago K, Williams RT, Zindy F, Roussel MF. p53-Dependent and -independent functions of the Arf tumor suppressor. Cold Spring Harbor Symposia On Quantitative Biology. 70: 129-37. PMID 16869746 DOI: 10.1101/Sqb.2005.70.004  0.451
2005 Uziel T, Zindy F, Xie S, Lee Y, Forget A, Magdaleno S, Rehg JE, Calabrese C, Solecki D, Eberhart CG, Sherr SE, Plimmer S, Clifford SC, Hatten ME, McKinnon PJ, ... ... Roussel MF, et al. The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes & Development. 19: 2656-67. PMID 16260494 DOI: 10.1101/Gad.1368605  0.45
2005 Williams RT, Roussel MF, Sherr CJ. Genetic Interaction of the BCR-ABL Oncogene and the ARF Tumor Suppressor in Ph+ Lymphoid Leukemia. Blood. 106: 240-240. DOI: 10.1182/Blood.V106.11.240.240  0.413
2004 Bertwistle D, Zindy F, Sherr CJ, Roussel MF. Monoclonal antibodies to the mouse p19(Arf) tumor suppressor protein. Hybridoma and Hybridomics. 23: 293-300. PMID 15672607 DOI: 10.1089/Hyb.2004.23.293  0.343
2004 Kuo ML, den Besten W, Bertwistle D, Roussel MF, Sherr CJ. N-terminal polyubiquitination and degradation of the Arf tumor suppressor. Genes & Development. 18: 1862-74. PMID 15289458 DOI: 10.1101/Gad.1213904  0.344
2004 Wrobel CN, Debnath J, Lin E, Beausoleil S, Roussel MF, Brugge JS. Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture. The Journal of Cell Biology. 165: 263-73. PMID 15117969 DOI: 10.1083/Jcb.200309102  0.312
2004 Yokota T, Matsuzaki Y, Miyazawa K, Zindy F, Roussel MF, Sakai T. Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. Oncogene. 23: 5340-9. PMID 15107822 DOI: 10.1038/Sj.Onc.1207689  0.395
2003 Zindy F, Williams RT, Baudino TA, Rehg JE, Skapek SX, Cleveland JL, Roussel MF, Sherr CJ. Arf tumor suppressor promoter monitors latent oncogenic signals in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 15930-5. PMID 14665695 DOI: 10.1073/Pnas.2536808100  0.41
2003 Zindy F, Nilsson LM, Nguyen L, Meunier C, Smeyne RJ, Rehg JE, Eberhart C, Sherr CJ, Roussel MF. Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice. Cancer Research. 63: 5420-7. PMID 14500377  0.304
2003 Baudino TA, Maclean KH, Brennan J, Parganas E, Yang C, Aslanian A, Lees JA, Sherr CJ, Roussel MF, Cleveland JL. Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. Molecular Cell. 11: 905-14. PMID 12718877 DOI: 10.1016/S1097-2765(03)00102-3  0.42
2003 Chen P, Zindy F, Abdala C, Liu F, Li X, Roussel MF, Segil N. Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nature Cell Biology. 5: 422-6. PMID 12717441 DOI: 10.1038/Ncb976  0.346
2003 Sugimoto M, Kuo ML, Roussel MF, Sherr CJ. Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing. Molecular Cell. 11: 415-24. PMID 12620229 DOI: 10.1016/S1097-2765(03)00057-1  0.41
2003 Kuo ML, Duncavage EJ, Mathew R, den Besten W, Pei D, Naeve D, Yamamoto T, Cheng C, Sherr CJ, Roussel MF. Arf induces p53-dependent and -independent antiproliferative genes. Cancer Research. 63: 1046-53. PMID 12615721  0.317
2002 Roussel MF. p53: regular or super? Cancer Cell. 2: 434-5. PMID 12498711 DOI: 10.1016/S1535-6108(02)00216-7  0.35
2002 Cunningham JJ, Levine EM, Zindy F, Goloubeva O, Roussel MF, Smeyne RJ. The cyclin-dependent kinase inhibitors p19(Ink4d) and p27(Kip1) are coexpressed in select retinal cells and act cooperatively to control cell cycle exit. Molecular and Cellular Neurosciences. 19: 359-74. PMID 11906209 DOI: 10.1006/Mcne.2001.1090  0.397
2001 Eischen CM, Roussel MF, Korsmeyer SJ, Cleveland JL. Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis. Molecular and Cellular Biology. 21: 7653-62. PMID 11604501 DOI: 10.1128/Mcb.21.22.7653-7662.2001  0.397
2001 Randle DH, Zindy F, Sherr CJ, Roussel MF. Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages. Proceedings of the National Academy of Sciences of the United States of America. 98: 9654-9. PMID 11481442 DOI: 10.1073/Pnas.171217498  0.769
2001 Eischen CM, Woo D, Roussel MF, Cleveland JL. Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis. Molecular and Cellular Biology. 21: 5063-70. PMID 11438662 DOI: 10.1128/Mcb.21.15.5063-5070.2001  0.302
2001 Drissi R, Zindy F, Roussel MF, Cleveland JL. c-Myc-mediated regulation of telomerase activity is disabled in immortalized cells. The Journal of Biological Chemistry. 276: 29994-30001. PMID 11402027 DOI: 10.1074/Jbc.M101899200  0.403
2001 Zindy F, den Besten W, Chen B, Rehg JE, Latres E, Barbacid M, Pollard JW, Sherr CJ, Cohen PE, Roussel MF. Control of spermatogenesis in mice by the cyclin D-dependent kinase inhibitors p18(Ink4c) and p19(Ink4d). Molecular and Cellular Biology. 21: 3244-55. PMID 11287627 DOI: 10.1128/Mcb.21.9.3244-3255.2001  0.352
2000 Buijs A, van Rompaey L, Molijn AC, Davis JN, Vertegaal AC, Potter MD, Adams C, van Baal S, Zwarthoff EC, Roussel MF, Grosveld GC. The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity. Molecular and Cellular Biology. 20: 9281-93. PMID 11094079 DOI: 10.1128/Mcb.20.24.9281-9293.2000  0.311
2000 Weber JD, Jeffers JR, Rehg JE, Randle DH, Lozano G, Roussel MF, Sherr CJ, Zambetti GP. p53-independent functions of the p19(ARF) tumor suppressor. Genes & Development. 14: 2358-65. PMID 10995391 DOI: 10.1101/Gad.827300  0.77
2000 Groth A, Weber JD, Willumsen BM, Sherr CJ, Roussel MF. Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases. The Journal of Biological Chemistry. 275: 27473-80. PMID 10842176 DOI: 10.1074/Jbc.M003417200  0.404
2000 O'Farrell AM, Parry DA, Zindy F, Roussel MF, Lees E, Moore KW, Mui AL. Stat3-dependent induction of p19INK4D by IL-10 contributes to inhibition of macrophage proliferation. Journal of Immunology (Baltimore, Md. : 1950). 164: 4607-15. PMID 10779764 DOI: 10.4049/Jimmunol.164.9.4607  0.305
2000 Weber JD, Kuo ML, Bothner B, DiGiammarino EL, Kriwacki RW, Roussel MF, Sherr CJ. Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex. Molecular and Cellular Biology. 20: 2517-28. PMID 10713175 DOI: 10.1128/Mcb.20.7.2517-2528.2000  0.372
2000 Zindy F, van Deursen J, Grosveld G, Sherr CJ, Roussel MF. INK4d-deficient mice are fertile despite testicular atrophy. Molecular and Cellular Biology. 20: 372-8. PMID 10594039 DOI: 10.1128/Mcb.20.1.372-378.2000  0.432
2000 Sexl V, Piekorz R, Moriggl R, Rohrer J, Brown MP, Bunting KD, Rothammer K, Roussel MF, Ihle JN. Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5. Blood. 96: 2277-2283. DOI: 10.1182/Blood.V96.6.2277.H8002277_2277_2283  0.319
2000 Inoue K, Wen R, Rehg JE, Adachi M, Cleveland JL, Roussel MF, Sherr CJ. Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis Genes & Development. 14: 1797-1809. DOI: 10.1101/Gad.14.14.1797  0.429
1999 Weber JD, Taylor LJ, Roussel MF, Sherr CJ, Bar-Sagi D. Nucleolar Arf sequesters Mdm2 and activates p53. Nature Cell Biology. 1: 20-6. PMID 10559859 DOI: 10.1038/8991  0.369
1999 Zindy F, Cunningham JJ, Sherr CJ, Jogal S, Smeyne RJ, Roussel MF. Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases. Proceedings of the National Academy of Sciences of the United States of America. 96: 13462-7. PMID 10557343 DOI: 10.1073/Pnas.96.23.13462  0.347
1999 Eischen CM, Weber JD, Roussel MF, Sherr CJ, Cleveland JL. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes & Development. 13: 2658-69. PMID 10541552 DOI: 10.1101/Gad.13.20.2658  0.441
1999 Roussel MF. The INK4 family of cell cycle inhibitors in cancer. Oncogene. 18: 5311-5317. PMID 10498883 DOI: 10.1038/Sj.Onc.1202998  0.425
1999 Inoue K, Roussel MF, Sherr CJ. Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1. Proceedings of the National Academy of Sciences of the United States of America. 96: 3993-8. PMID 10097151 DOI: 10.1073/Pnas.96.7.3993  0.423
1999 Bodner SM, Naeve CW, Rakestraw KM, Jones BG, Valentine VA, Valentine MB, Luthardt FW, Willman CL, Raimondi SC, Downing JR, Roussel MF, Sherr CJ, Look AT. Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1). Gene. 229: 223-8. PMID 10095122 DOI: 10.1016/S0378-1119(98)00591-5  0.32
1999 Cheng M, Olivier P, Diehl JA, Fero M, Roussel MF, Roberts JM, Sherr CJ. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. The Embo Journal. 18: 1571-83. PMID 10075928 DOI: 10.1093/Emboj/18.6.1571  0.363
1999 Cheng M, Wang D, Roussel MF. Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1. Journal of Biological Chemistry. 274: 6553-6558. PMID 10037749 DOI: 10.1074/Jbc.274.10.6553  0.337
1999 Sexl V, Diehl JA, Sherr CJ, Ashmun R, Beach D, Roussel MF. A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2. Oncogene. 18: 573-82. PMID 9989807 DOI: 10.1038/Sj.Onc.1202362  0.342
1999 Gómez Lahoz E, Liegeois NJ, Zhang P, Engelman JA, Horner J, Silverman A, Burde R, Roussel MF, Sherr CJ, Elledge SJ, DePinho RA. Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivo. Molecular and Cellular Biology. 19: 353-63. PMID 9858559 DOI: 10.1128/Mcb.19.1.353  0.359
1998 de Stanchina E, McCurrach ME, Zindy F, Shieh SY, Ferbeyre G, Samuelson AV, Prives C, Roussel MF, Sherr CJ, Lowe SW. E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes & Development. 12: 2434-42. PMID 9694807 DOI: 10.1101/Gad.12.15.2434  0.408
1998 Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes & Development. 12: 2424-33. PMID 9694806 DOI: 10.1101/Gad.12.15.2424  0.777
1998 Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ. Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proceedings of the National Academy of Sciences of the United States of America. 95: 8292-7. PMID 9653180 DOI: 10.1073/Pnas.95.14.8292  0.405
1998 Roussel MF. Key effectors of signal transduction and G1 progression. Advances in Cancer Research. 74: 1-24. PMID 9561265 DOI: 10.1016/S0065-230X(08)60763-0  0.338
1998 Cheng M, Sexl V, Sherr CJ, Roussel MF. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proceedings of the National Academy of Sciences of the United States of America. 95: 1091-6. PMID 9448290 DOI: 10.1073/Pnas.95.3.1091  0.356
1998 Altura RA, Inukai T, Ashmun RA, Zambetti GP, Roussel MF, Look AT. The Chimeric E2A-HLF Transcription Factor Abrogates p53-Induced Apoptosis in Myeloid Leukemia Cells Blood. 92: 1397-1405. DOI: 10.1182/Blood.V92.4.1397.416K19_1397_1405  0.398
1997 Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, Ashmun RA, Grosveld G, Sherr CJ. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell. 91: 649-59. PMID 9393858 DOI: 10.1016/S0092-8674(00)80452-3  0.435
1997 Davis JN, Rock CO, Cheng M, Watson JB, Ashmun RA, Kirk H, Kay RJ, Roussel MF. Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase. Molecular and Cellular Biology. 17: 7398-406. PMID 9372970 DOI: 10.1128/Mcb.17.12.7398  0.332
1997 Zindy F, Quelle DE, Roussel MF, Sherr CJ. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene. 15: 203-11. PMID 9244355 DOI: 10.1038/Sj.Onc.1201178  0.382
1997 Roussel MF. Regulation of cell cycle entry and G1 progression by CSF‐1 Molecular Reproduction and Development. 46: 11-18. PMID 8981358 DOI: 10.1002/(Sici)1098-2795(199701)46:1<11::Aid-Mrd3>3.0.Co;2-U  0.369
1997 Adachi M, Roussel MF, Havenith K, Sherr CJ. Features of Macrophage Differentiation Induced by p19INK4d, a Specific Inhibitor of Cyclin D–Dependent Kinases Blood. 90: 126-137. DOI: 10.1182/Blood.V90.1.126  0.347
1996 Roussel MF, Ashmun RA, Sherr CJ, Eisenman RN, Ayer DE. Inhibition of cell proliferation by the Mad1 transcriptional repressor. Molecular and Cellular Biology. 16: 2796-801. PMID 8649388 DOI: 10.1128/Mcb.16.6.2796  0.367
1995 Hirai H, Roussel MF, Kato JY, Ashmun RA, Sherr CJ. Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D- dependent kinases CDK4 and CDK6 Molecular and Cellular Biology. 15: 2672-2681. PMID 7739547 DOI: 10.1128/Mcb.15.5.2672  0.378
1995 Roussel MF, Theodoras AM, Pagano M, Sherr CJ. Rescue of defective mitogenic signaling by D-type cyclins Proceedings of the National Academy of Sciences of the United States of America. 92: 6837-6841. PMID 7624328 DOI: 10.1073/Pnas.92.15.6837  0.337
1994 Roussel MF. Signal transduction by the macrophage-colony-stimulating factor receptor (CSF-1R). Journal of Cell Science. 1994: 105-108. PMID 7883784 DOI: 10.1242/Jcs.1994.Supplement_18.15  0.352
1993 Quelle DE, Ashmun RA, Shurtleff SA, Kato JY, Bar-Sagi D, Roussel MF, Sherr CJ. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts Genes and Development. 7: 1559-1571. PMID 8339933 DOI: 10.1101/Gad.7.8.1559  0.317
1992 Matsushime H, Ewen ME, Strom DK, Kato JY, Hanks SK, Roussel MF, Sherr CJ. Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins Cell. 71: 323-334. PMID 1423597 DOI: 10.1016/0092-8674(92)90360-O  0.308
1992 Inaba T, Matsushime H, Valentine M, Roussel MF, Sherr CJ, Look AT. Genomic organization, chromosomal localization, and independent expression of human cyclin D genes Genomics. 13: 565-574. PMID 1386335 DOI: 10.1016/0888-7543(92)90126-D  0.316
1991 Matsushime H, Roussel MF, Ashmun RA, Sherr CJ. Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle Cell. 65: 701-713. PMID 1827757 DOI: 10.1016/0092-8674(91)90101-4  0.324
1991 Bortner DM, Ulivi M, Roussel MF, Ostrowski MC. The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor. Genes & Development. 5: 1777-85. PMID 1717344 DOI: 10.1101/Gad.5.10.1777  0.309
1990 Roussel MF, Shurtleff SA, Downing JR, Sherr CJ. A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes Proceedings of the National Academy of Sciences of the United States of America. 87: 6738-6742. PMID 2168557 DOI: 10.1073/Pnas.87.17.6738  0.318
1989 Roussel MF, Sherr CJ. Mouse NIH 3T3 cells expressing human colony-stimulating factor 1 (CSF-1) receptors overgrow in serum-free medium containing human CSF-1 as their only growth factor Proceedings of the National Academy of Sciences of the United States of America. 86: 7924-7927. PMID 2554296 DOI: 10.1073/Pnas.86.20.7924  0.324
1988 Roussel MF, Rettenmier CW, Sherr CJ. Introduction of a human colony stimulating factor-1 gene into a mouse macrophage cell line induces CSF-1 independence but not tumorigenicity Blood. 71: 1218-1225. PMID 3282567 DOI: 10.1182/Blood.V71.5.1218.Bloodjournal7151218  0.345
1988 Rettenmier CW, Roussel MF, Sherr CJ. The conoly-stimulating factor 1 (CSF-1) receptor (c-fms proto-oncogene product) and its ligand Journal of Cell Science. 27-44. PMID 2978516 DOI: 10.1242/Jcs.1988.Supplement_9.2  0.361
1988 Sherr CJ, Roussel MF, Rettenmier CW. Colony-stimulating factor-1 receptor (c-fms) Journal of Cellular Biochemistry. 38: 179-187. PMID 2852667 DOI: 10.1002/Jcb.240380305  0.32
1988 Roussel MF, Downing JR, Ashmun RA, Rettenmier CW, Sherr CJ. Colony-stimulating factor 1-mediated regulation of a chimeric c-fms/v-fms receptor containing the v-fms-encoded tyrosine kinase domain Proceedings of the National Academy of Sciences of the United States of America. 85: 5903-5907. PMID 2842754 DOI: 10.1073/Pnas.85.16.5903  0.324
1987 Rettenmier CW, Roussel MF, Ashmun RA, Ralph P, Price K, Sherr CJ. Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes. Molecular and Cellular Biology. 7: 2378-87. PMID 3039346 DOI: 10.1128/Mcb.7.7.2378  0.311
1987 Roussel MF, Dull TJ, Rettenmier CW, Ralph P, Ullrich A, Sherr CJ. Transforming potential of the c-fms proto-oncogene (CSF-1 receptor). Nature. 325: 549-52. PMID 3027579 DOI: 10.1038/325549A0  0.301
1987 Heard JM, Roussel MF, Rettenmier CW, Sherr CJ. Multilineage hematopoietic disorders induced by transplantation of bone marrow cells expressing the v-fms oncogene Cell. 51: 663-673. PMID 2824063 DOI: 10.1016/0092-8674(87)90135-8  0.302
1985 Roussel MF, Rettenmier CW, Look AT, Sherr CJ. Cell surface expression of v-fms-coded glycoproteins is required for transformation. Molecular and Cellular Biology. 4: 1999-2009. PMID 6390182 DOI: 10.1128/Mcb.4.10.1999  0.307
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