Year |
Citation |
Score |
2024 |
Egan BM, Pohl F, Anderson X, Williams SC, Adodo IG, Hunt P, Wang Z, Chiu CH, Scharf A, Mosley M, Kumar S, Schneider DL, Fujiwara H, Hsu FF, Kornfeld K. The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging. Development (Cambridge, England). PMID 38284547 DOI: 10.1242/dev.202146 |
0.339 |
|
2023 |
Egan BM, Pohl F, Anderson X, Williams SC, Adodo IG, Hunt P, Wang Z, Chiu CH, Scharf A, Mosley M, Kumar S, Schneider DL, Fujiwara H, Hsu FF, Kornfeld K. The ACE-inhibitor drug captopril inhibits ACN-1 to control dauer formation and aging. Biorxiv : the Preprint Server For Biology. PMID 37502959 DOI: 10.1101/2023.07.17.549402 |
0.331 |
|
2022 |
Egan BM, Scharf A, Pohl F, Kornfeld K. Control of aging by the renin-angiotensin system: a review of and mammals. Frontiers in Pharmacology. 13: 938650. PMID 36188619 DOI: 10.3389/fphar.2022.938650 |
0.307 |
|
2019 |
Murphy JT, Liu H, Ma X, Shaver A, Egan BM, Oh C, Boyko A, Mazer T, Ang S, Khopkar R, Javaheri A, Kumar S, Jiang X, Ory D, Mani K, ... ... Kornfeld K, et al. Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival. Plos Biology. 17: e3000245. PMID 31086360 DOI: 10.1371/Journal.Pbio.3000245 |
0.392 |
|
2019 |
Kumar S, Egan BM, Kocsisova Z, Schneider DL, Murphy JT, Diwan A, Kornfeld K. Lifespan Extension in C. elegans Caused by Bacterial Colonization of the Intestine and Subsequent Activation of an Innate Immune Response. Developmental Cell. 49: 100-117.e6. PMID 30965033 DOI: 10.1016/J.Devcel.2019.03.010 |
0.406 |
|
2019 |
Kocsisova Z, Kornfeld K, Schedl T. Rapid, population-wide declines in stem cell number and activity during reproductive aging in . Development (Cambridge, England). PMID 30936182 DOI: 10.1242/Dev.173195 |
0.396 |
|
2018 |
Kocsisova Z, Mohammad A, Kornfeld K, Schedl T. Cell Cycle Analysis in the C. elegans Germline with the Thymidine Analog EdU. Journal of Visualized Experiments : Jove. PMID 30394383 DOI: 10.3791/58339 |
0.309 |
|
2018 |
Zhao Y, Tan CH, Krauchunas A, Scharf A, Dietrich N, Warnhoff K, Yuan Z, Druzhinina M, Gu SG, Miao L, Singson A, Ellis RE, Kornfeld K. The zinc transporter ZIPT-7.1 regulates sperm activation in nematodes. Plos Biology. 16: e2005069. PMID 29879108 DOI: 10.1371/Journal.Pbio.2005069 |
0.61 |
|
2018 |
Kocsisova Z, Kornfeld K, Schedl T. Cell cycle accumulation of the proliferating cell nuclear antigen PCN-1 transitions from continuous in the adult germline to intermittent in the early embryo of C. elegans. Bmc Developmental Biology. 18: 12. PMID 29848313 DOI: 10.1186/S12861-018-0171-7 |
0.303 |
|
2017 |
Dietrich N, Schneider DL, Kornfeld K. A pathway for low zinc homeostasis that is conserved in animals and acts in parallel to the pathway for high zinc homeostasis. Nucleic Acids Research. PMID 28977437 DOI: 10.1093/Nar/Gkx762 |
0.417 |
|
2017 |
Warnhoff K, Roh HC, Kocsisova Z, Tan CH, Morrison A, Croswell D, Schneider DL, Kornfeld K. The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc. Plos Biology. 15: e2000094. PMID 28095401 DOI: 10.1371/Journal.Pbio.2000094 |
0.686 |
|
2016 |
Dietrich N, Tan CH, Cubillas C, Earley BJ, Kornfeld K. Insights into zinc and cadmium biology in the nematode C. elegans. Archives of Biochemistry and Biophysics. PMID 27261336 DOI: 10.1016/J.Abb.2016.05.021 |
0.381 |
|
2016 |
Kumar S, Dietrich N, Kornfeld K. Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span. Plos Genetics. 12: e1005866. PMID 26918946 DOI: 10.1371/Journal.Pgen.1005866 |
0.431 |
|
2015 |
Leight ER, Murphy JT, Fantz DA, Pepin D, Schneider DL, Ratliff TM, Mohammad DH, Herman MA, Kornfeld K. Conversion of the LIN-1 ETS protein of Caenorhabditis elegans from a SUMOylated transcriptional repressor to a phosphorylated transcriptional activator. Genetics. 199: 761-75. PMID 25567989 DOI: 10.1534/Genetics.114.172668 |
0.661 |
|
2015 |
Roh HC, Dimitrov I, Deshmukh K, Zhao G, Warnhoff K, Cabrera D, Tsai W, Kornfeld K. A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans. Nucleic Acids Research. 43: 803-16. PMID 25552416 DOI: 10.1093/Nar/Gku1360 |
0.728 |
|
2014 |
Kumar S, Kocsisova Z, Kornfeld K. Keep on laying eggs Mama, RNAi my reproductive aging blues away. Plos Genetics. 10: e1004808. PMID 25474201 DOI: 10.1371/Journal.Pgen.1004808 |
0.446 |
|
2014 |
Warnhoff K, Murphy JT, Kumar S, Schneider DL, Peterson M, Hsu S, Guthrie J, Robertson JD, Kornfeld K. The DAF-16 FOXO transcription factor regulates natc-1 to modulate stress resistance in Caenorhabditis elegans, linking insulin/IGF-1 signaling to protein N-terminal acetylation. Plos Genetics. 10: e1004703. PMID 25330323 DOI: 10.1371/Journal.Pgen.1004703 |
0.356 |
|
2013 |
Pickett CL, Dietrich N, Chen J, Xiong C, Kornfeld K. Mated progeny production is a biomarker of aging in Caenorhabditis elegans. G3 (Bethesda, Md.). 3: 2219-32. PMID 24142929 DOI: 10.1534/G3.113.008664 |
0.357 |
|
2013 |
Roh HC, Collier S, Deshmukh K, Guthrie J, Robertson JD, Kornfeld K. ttm-1 encodes CDF transporters that excrete zinc from intestinal cells of C. elegans and act in a parallel negative feedback circuit that promotes homeostasis. Plos Genetics. 9: e1003522. PMID 23717214 DOI: 10.1371/Journal.Pgen.1003522 |
0.719 |
|
2013 |
Pickett CL, Kornfeld K. Age-related degeneration of the egg-laying system promotes matricidal hatching in Caenorhabditis elegans Aging Cell. 12: 544-553. PMID 23551912 DOI: 10.1111/Acel.12079 |
0.411 |
|
2012 |
Roh HC, Collier S, Guthrie J, Robertson JD, Kornfeld K. Lysosome-related organelles in intestinal cells are a zinc storage site in C. elegans. Cell Metabolism. 15: 88-99. PMID 22225878 DOI: 10.1016/J.Cmet.2011.12.003 |
0.73 |
|
2011 |
Hughes SE, Huang C, Kornfeld K. Identification of mutations that delay somatic or reproductive aging of Caenorhabditis elegans. Genetics. 189: 341-56. PMID 21750263 DOI: 10.1534/Genetics.111.130450 |
0.773 |
|
2011 |
Murphy JT, Bruinsma JJ, Schneider DL, Collier S, Guthrie J, Chinwalla A, Robertson JD, Mardis ER, Kornfeld K. Histidine protects against zinc and nickel toxicity in Caenorhabditis elegans. Plos Genetics. 7: e1002013. PMID 21455490 DOI: 10.1371/Journal.Pgen.1002013 |
0.788 |
|
2010 |
Johnson KG, Kornfeld K. The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation. Developmental Biology. 341: 464-71. PMID 20230813 DOI: 10.1016/J.Ydbio.2010.03.003 |
0.405 |
|
2009 |
Davis DE, Roh HC, Deshmukh K, Bruinsma JJ, Schneider DL, Guthrie J, Robertson JD, Kornfeld K. The cation diffusion facilitator gene cdf-2 mediates zinc metabolism in Caenorhabditis elegans. Genetics. 182: 1015-33. PMID 19448268 DOI: 10.1534/Genetics.109.103614 |
0.754 |
|
2008 |
Collins JJ, Evason K, Pickett CL, Schneider DL, Kornfeld K. The anticonvulsant ethosuximide disrupts sensory function to extend C. elegans lifespan. Plos Genetics. 4: e1000230. PMID 18949032 DOI: 10.1371/Journal.Pgen.1000230 |
0.72 |
|
2008 |
Bruinsma JJ, Schneider DL, Davis DE, Kornfeld K. Identification of mutations in Caenorhabditis elegans that cause resistance to high levels of dietary zinc and analysis using a genomewide map of single nucleotide polymorphisms scored by pyrosequencing. Genetics. 179: 811-28. PMID 18505880 DOI: 10.1534/Genetics.107.084384 |
0.772 |
|
2008 |
Collins JJ, Huang C, Hughes S, Kornfeld K. The measurement and analysis of age-related changes in Caenorhabditis elegans. Wormbook : the Online Review of C. Elegans Biology. 1-21. PMID 18381800 DOI: 10.1895/Wormbook.1.137.1 |
0.748 |
|
2008 |
Evason K, Collins JJ, Huang C, Hughes S, Kornfeld K. Valproic acid extends Caenorhabditis elegans lifespan. Aging Cell. 7: 305-17. PMID 18248662 DOI: 10.1111/J.1474-9726.2008.00375.X |
0.759 |
|
2007 |
Hughes SE, Evason K, Xiong C, Kornfeld K. Genetic and pharmacological factors that influence reproductive aging in nematodes. Plos Genetics. 3: e25. PMID 17305431 DOI: 10.1371/Journal.Pgen.0030025 |
0.76 |
|
2006 |
Collins JJ, Evason K, Kornfeld K. Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans. Experimental Gerontology. 41: 1032-9. PMID 16872777 DOI: 10.1016/J.Exger.2006.06.038 |
0.69 |
|
2006 |
Wagmaister JA, Miley GR, Morris CA, Gleason JE, Miller LM, Kornfeld K, Eisenmann DM. Identification of cis-regulatory elements from the C. elegans Hox gene lin-39 required for embryonic expression and for regulation by the transcription factors LIN-1, LIN-31 and LIN-39. Developmental Biology. 297: 550-65. PMID 16782085 DOI: 10.1016/J.Ydbio.2006.05.008 |
0.726 |
|
2006 |
Kornfeld K, Evason K. Effects of anticonvulsant drugs on life span. Archives of Neurology. 63: 491-6. PMID 16606760 DOI: 10.1001/Archneur.63.4.491 |
0.705 |
|
2006 |
Goldstein JL, Glossip D, Nayak S, Kornfeld K. The CRAL/TRIO and GOLD domain protein CGR-1 promotes induction of vulval cell fates in Caenorhabditis elegans and interacts genetically with the Ras signaling pathway. Genetics. 172: 929-42. PMID 16219793 DOI: 10.1534/Genetics.104.035550 |
0.44 |
|
2005 |
Leight ER, Glossip D, Kornfeld K. Sumoylation of LIN-1 promotes transcriptional repression and inhibition of vulval cell fates. Development (Cambridge, England). 132: 1047-56. PMID 15689373 DOI: 10.1242/Dev.01664 |
0.357 |
|
2005 |
Evason K, Huang C, Yamben I, Covey DF, Kornfeld K. Anticonvulsant medications extend worm life-span. Science (New York, N.Y.). 307: 258-62. PMID 15653505 DOI: 10.1126/Science.1105299 |
0.693 |
|
2004 |
Miley GR, Fantz D, Glossip D, Lu X, Saito RM, Palmer RE, Inoue T, Van Den Heuvel S, Sternberg PW, Kornfeld K. Identification of residues of the Caenorhabditis elegans LIN-1 ETS domain that are necessary for DNA binding and regulation of vulval cell fates. Genetics. 167: 1697-709. PMID 15342509 DOI: 10.1534/Genetics.104.029017 |
0.719 |
|
2003 |
Harding A, Hsu V, Kornfeld K, Hancock JF. Identification of residues and domains of Raf important for function in vivo and in vitro. The Journal of Biological Chemistry. 278: 45519-27. PMID 12954633 DOI: 10.1074/Jbc.M303106200 |
0.43 |
|
2002 |
Bruinsma JJ, Jirakulaporn T, Muslin AJ, Kornfeld K. Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling. Developmental Cell. 2: 567-78. PMID 12015965 DOI: 10.1016/S1534-5807(02)00151-X |
0.756 |
|
2002 |
Hsu V, Zobel CL, Lambie EJ, Schedl T, Kornfeld K. Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates. Genetics. 160: 481-92. PMID 11861555 |
0.317 |
|
2001 |
Fantz DA, Jacobs D, Glossip D, Kornfeld K. Docking Sites on Substrate Proteins Direct Extracellular Signal-regulated Kinase to Phosphorylate Specific Residues Journal of Biological Chemistry. 276: 27256-27265. DOI: 10.1074/Jbc.M102512200 |
0.316 |
|
1997 |
Xing H, Kornfeld K, Muslin AJ. The protein kinase KSR interacts with 14-3-3 protein and Raf. Current Biology : Cb. 7: 294-300. PMID 9115393 DOI: 10.1016/S0960-9822(06)00152-7 |
0.635 |
|
1997 |
Kornfeld K. Vulval development in Caenorhabditis elegans. Trends in Genetics : Tig. 13: 55-61. PMID 9055606 DOI: 10.1016/S0168-9525(97)01005-6 |
0.327 |
|
1995 |
Kornfeld K, Hom DB, Horvitz HR. The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans. Cell. 83: 903-13. PMID 8521514 DOI: 10.1016/0092-8674(95)90206-6 |
0.604 |
|
1995 |
Kornfeld K, Guan KL, Horvitz HR. The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK. Genes & Development. 9: 756-68. PMID 7729691 DOI: 10.1101/Gad.9.6.756 |
0.602 |
|
1994 |
Lackner MR, Kornfeld K, Miller LM, Horvitz HR, Kim SK. A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans. Genes & Development. 8: 160-73. PMID 8299936 DOI: 10.1101/Gad.8.2.160 |
0.585 |
|
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