Francis G. Spinale - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Animal Physiology Biology, Cell Biology, Pathology

343 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Spinale FG, Carabello BA. The Pathology of Primary Mitral Regurgitation: The Matrix Is at the Heart of the Matter. Jacc. Basic to Translational Science. 7: 982-984. PMID 36337922 DOI: 10.1016/j.jacbts.2022.06.018  0.36
2022 Thorn SL, Shuman JA, Stacy MR, Purcell BP, Doviak H, Burdick JA, Spinale FG, Sinusas AJ. Matrix Metalloproteinase-Targeted SPECT/CT Imaging for Evaluation of Therapeutic Hydrogels for the Early Modulation of Post-Infarct Myocardial Remodeling. Journal of Cardiovascular Translational Research. PMID 35697979 DOI: 10.1007/s12265-022-10280-7  0.456
2022 Stacy MR, Lin BA, Thorn SL, Lobb DC, Maxfield MW, Novack C, Zellars KN, Freeburg L, Akar JG, Sinusas AJ, Spinale FG. Regional heterogeneity in determinants of atrial matrix remodeling and association with atrial fibrillation vulnerability postmyocardial infarction. Heart Rhythm. PMID 35066183 DOI: 10.1016/j.hrthm.2022.01.022  0.475
2021 Lindsey ML, Brunt KR, Kirk JA, Kleinbongard P, Calvert JW, de Castro Brás LE, DeLeon-Pennell KY, Del Re DP, Frangogiannis NG, Frantz S, Gumina RJ, Halade G, Jones SP, Ritchie RH, Spinale FG, et al. Guidelines for in vivo mouse models of myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34623181 DOI: 10.1152/ajpheart.00459.2021  0.302
2021 Snyder LB, Lai Y, Doviak H, Freeburg LA, Laney VK, Moore A, Zellars KN, Matesic LE, Spinale FG. Ubiquitin Ligase Wwp1 Gene Deletion Attenuates Diastolic Dysfunction in Pressure Overload Hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34559578 DOI: 10.1152/ajpheart.00032.2021  0.337
2021 Young BD, Moreland H, Oatmen KE, Freeburg LA, Shahab Z, Herzog E, Miller EJ, Spinale FG. Cytokine Signaling and Matrix Remodeling Pathways Associated with Cardiac Sarcoidosis Disease Activity Defined Using FDG PET Imaging. International Heart Journal. PMID 34544982 DOI: 10.1536/ihj.21-164  0.328
2021 Spinale FG. Injectable Biomaterials and Myocardial Infarction: Gaining a Toehold in an Unstable Matrix. Jacc. Basic to Translational Science. 6: 362-364. PMID 33999041 DOI: 10.1016/j.jacbts.2021.01.010  0.362
2020 Boutagy NE, Feher A, Pfau D, Liu Z, Guerrera NM, Freeburg LA, Womack SJ, Hoenes AC, Zeiss C, Young LH, Spinale FG, Sinusas AJ. Dual Angiotensin Receptor-Neprilysin Inhibition With Sacubitril/Valsartan Attenuates Systolic Dysfunction in Experimental Doxorubicin-Induced Cardiotoxicity. Jacc. Cardiooncology. 2: 774-787. PMID 33437965 DOI: 10.1016/j.jaccao.2020.09.007  0.471
2020 Lobb D, Doviak H, Brower G, Romito E, O'Neill J, Smith S, Shuman J, Freels P, Zellars K, Freeburg L, Khakoo A, Lee T, Spinale FG. . The Journal of Pharmacology and Experimental Therapeutics. PMID 32958629 DOI: 10.1124/Jpet.120.000047  0.511
2020 Matesic LE, Freeburg LA, Snyder L, Duncan LM, Moore A, Perreault PE, Zellars KN, Goldsmith EC, Spinale FG. The Ubiquitin Ligase WWP1 Contributes to Shifts in Matrix Proteolytic Profiles and a Myocardial Ageing Phenotype with Diastolic Heart Failure. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32822210 DOI: 10.1152/Ajpheart.00620.2019  0.409
2020 Torres WM, Barlow SC, Moore A, Freeburg LA, Hoenes A, Doviak H, Zile MR, Shazly T, Spinale FG. Changes in Myocardial Microstructure and Mechanics With Progressive Left Ventricular Pressure Overload. Jacc. Basic to Translational Science. 5: 463-480. PMID 32478208 DOI: 10.1016/J.Jacbts.2020.02.007  0.449
2020 Lindsey ML, DeLeon-Pennell KY, Bradshaw AD, LaRue RAC, Anderson DR, Thiele GM, Baicu CF, Jones JA, Menick DR, Zile MR, Spinale FG. Focusing Heart Failure Research on Myocardial Fibrosis to Prioritize Translation. Journal of Cardiac Failure. PMID 32446948 DOI: 10.1016/J.Cardfail.2020.05.009  0.359
2020 Torres WM, Spinale FG, Shazly T. Speckle-Tracking Echocardiography Enables Model-Based Identification of Regional Stiffness Indices in the Left Ventricular Myocardium. Cardiovascular Engineering and Technology. PMID 31997092 DOI: 10.1007/S13239-020-00456-0  0.411
2019 Thorn SL, Barlow SC, Feher A, Stacy MR, Doviak H, Jacobs J, Zellars K, Renaud JM, Klein R, deKemp RA, Khakoo AY, Lee T, Spinale FG, Sinusas AJ. Application of Hybrid Matrix Metalloproteinase-Targeted and Dynamic Tl Single-Photon Emission Computed Tomography/Computed Tomography Imaging for Evaluation of Early Post-Myocardial Infarction Remodeling. Circulation. Cardiovascular Imaging. 12: e009055. PMID 31707811 DOI: 10.1161/Circimaging.119.009055  0.488
2019 Oatmen KE, Cull E, Spinale FG. Heart failure as interstitial cancer: emergence of a malignant fibroblast phenotype. Nature Reviews. Cardiology. PMID 31686012 DOI: 10.1038/S41569-019-0286-Y  0.404
2019 Carrick-Ranson G, Spinale FG, Bhella PS, Sarma S, Shibata S, Fujimoto N, Hastings JL, Levine BD. Plasma matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs and aging and lifelong exercise adaptations in ventricular and arterial stiffness. Experimental Gerontology. PMID 31095969 DOI: 10.1016/J.Exger.2019.05.004  0.478
2018 Oatmen KE, Zile MR, Burnett JC, Spinale FG. Bioactive Signaling in Next-Generation Pharmacotherapies for Heart Failure: A Review. Jama Cardiology. PMID 30484834 DOI: 10.1001/Jamacardio.2018.3789  0.331
2018 Torres WM, Jacobs J, Doviak H, Barlow SC, Zile MR, Shazly T, Spinale FG. Regional and temporal changes in left ventricular strain and stiffness in a porcine model of myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30004234 DOI: 10.1152/Ajpheart.00279.2018  0.382
2018 Purcell BP, Barlow SC, Perreault PE, Freeburg LA, Doviak H, Jacobs J, Hoenes A, Zellars KN, Khakoo AF, Lee T, Burdick JA, Spinale FG. Delivery of a Matrix Metalloproteinase Responsive Hydrogel Releasing TIMP-3 Following Myocardial Infarction: Effects on Left Ventricular Remodeling. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29979624 DOI: 10.1152/Ajpheart.00076.2018  0.488
2018 Genau MC, Perreault PE, Romito E, Doviak H, Logdon CB, Ruble S, Spinale FG. Institution of localized high-frequency electrical stimulation targeting early myocardial infarction: Effects on left ventricle function and geometry. The Journal of Thoracic and Cardiovascular Surgery. PMID 29609885 DOI: 10.1016/J.Jtcvs.2018.01.104  0.375
2018 Torres WM, Mealy JE, Jacobs J, Doviak H, Barlow SC, Burdick JA, Shazly T, Spinale FG. Biomaterial-Based Delivery of a Small Molecule Matrix Metalloproteinase Inhibitor Limits Adverse Biomechanical Changes Throughout the Left Ventricle Following Myocardial Infarction Journal of Cardiac Failure. 24: S40. DOI: 10.1016/J.Cardfail.2018.07.116  0.477
2018 Mealy JE, Barlow SC, Doviak H, Jacobs J, Torres WM, Burdick JA, Spinale FG. Targeted Delivery and Controlled Release of a Small Molecule Matrix Metalloproteinase Inhibitor Using a Self-Assembling Hydrogel Following Myocardial Infarction Journal of Cardiac Failure. 24: S17. DOI: 10.1016/J.Cardfail.2018.07.051  0.421
2018 Young B, Oatmen KE, Freeburg LA, Zellars KN, Sapp AA, Herzog E, Miller EJ, Spinale FG. Specific Pro-Inflammatory Signaling Pathways are Induced in Patients with Cardiac Sarcoidosis; Potential Prognostic/Therapeutic Applications Journal of Cardiac Failure. 24: S10. DOI: 10.1016/J.Cardfail.2018.07.033  0.336
2017 Spinale FG, Sapp AA. Cardiovascular Risk and Matrix Metalloproteinase Polymorphisms: Not Just a Simple Substitution. Circulation. Cardiovascular Genetics. 10: e001958. PMID 29212903 DOI: 10.1161/Circgenetics.117.001958  0.527
2017 Barlow SC, Doviak H, Jacobs J, Freeburg LA, Perreault PE, Zellars KN, Moreau K, Villacreses CF, Smith S, Khakoo AF, Lee T, Spinale FG. Intracoronary Delivery of Recombinant TIMP-3 Following Myocardial Infarction: Effects on Myocardial Remodeling and Function. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00114.2017. PMID 28754718 DOI: 10.1152/Ajpheart.00114.2017  0.551
2017 Romito E, Shazly T, Spinale FG. In-Vivo Assessment of Regional Mechanics Post-Myocardial Infarction: A Focus on the Road Ahead. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00589.2015. PMID 28235858 DOI: 10.1152/Japplphysiol.00589.2015  0.379
2016 Spinale FG, Frangogiannis NG, Hinz B, Holmes JW, Kassiri Z, Lindsey ML. Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research. Circulation Research. 119: 1040-1045. PMID 27789578 DOI: 10.1161/Circresaha.116.309916  0.387
2016 Spinale FG. Improving Delivery of a Biomaterial Payload in Myocardial Infarction. Circulation. Cardiovascular Interventions. 9. PMID 27729420 DOI: 10.1161/Circinterventions.116.004489  0.47
2016 Romito E, Doviak H, Logdon C, Freels P, Shazly T, Spinale FG. Sonomicrometry-Based Analysis of Post-Myocardial Infarction Regional Mechanics. Annals of Biomedical Engineering. PMID 27411709 DOI: 10.1007/S10439-016-1694-3  0.448
2016 Suzuki K, Satoh K, Ikeda S, Sunamura S, Otsuki T, Satoh T, Kikuchi N, Omura J, Kurosawa R, Nogi M, Numano K, Sugimura K, Aoki T, Tatebe S, Miyata S, ... ... Spinale FG, et al. Basigin Promotes Cardiac Fibrosis and Failure in Response to Chronic Pressure Overload in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 636-46. PMID 26916734 DOI: 10.1161/Atvbaha.115.306686  0.423
2015 Gopinathannair R, Etheridge SP, Marchlinski FE, Spinale FG, Lakkireddy D, Olshansky B. Arrhythmia-Induced Cardiomyopathies: Mechanisms, Recognition, and Management. Journal of the American College of Cardiology. 66: 1714-28. PMID 26449143 DOI: 10.1016/J.Jacc.2015.08.038  0.406
2015 Spinale FG. Assessment of Cardiac Function--Basic Principles and Approaches. Comprehensive Physiology. 5: 1911-46. PMID 26426471 DOI: 10.1002/Cphy.C140054  0.366
2015 Spinale FG, Gorman RC, Burdick JA. Author response: new therapies for reducing post-myocardial left ventricular remodeling. Annals of Translational Medicine. 3: 146. PMID 26207239 DOI: 10.3978/J.Issn.2305-5839.2015.06.07  0.492
2015 Mani SK, Kern CB, Kimbrough D, Addy B, Kasiganesan H, Rivers WT, Patel RK, Chou JC, Spinale FG, Mukherjee R, Menick DR. Inhibition of class I histone deacetylase activity represses matrix metalloproteinase-2 and -9 expression and preserves LV function postmyocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 308: H1391-401. PMID 25795711 DOI: 10.1152/Ajpheart.00390.2014  0.563
2015 McGarvey JR, Kondo N, Witschey WR, Takebe M, Aoki C, Burdick JA, Spinale FG, Gorman JH, Pilla JJ, Gorman RC. Injectable microsphere gel progressively improves global ventricular function, regional contractile strain, and mitral regurgitation after myocardial infarction. The Annals of Thoracic Surgery. 99: 597-603. PMID 25524397 DOI: 10.1016/J.Athoracsur.2014.09.014  0.409
2014 McGarvey JR, Pettaway S, Shuman JA, Novack CP, Zellars KN, Freels PD, Echols RL, Burdick JA, Gorman JH, Gorman RC, Spinale FG. Targeted injection of a biocomposite material alters macrophage and fibroblast phenotype and function following myocardial infarction: relation to left ventricular remodeling. The Journal of Pharmacology and Experimental Therapeutics. 350: 701-9. PMID 25022514 DOI: 10.1124/Jpet.114.215798  0.43
2014 Yarbrough WM, Baicu C, Mukherjee R, Van Laer A, Rivers WT, McKinney RA, Prescott CB, Stroud RE, Freels PD, Zellars KN, Zile MR, Spinale FG. Cardiac-restricted overexpression or deletion of tissue inhibitor of matrix metalloproteinase-4: differential effects on left ventricular structure and function following pressure overload-induced hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 307: H752-61. PMID 24993046 DOI: 10.1152/Ajpheart.00063.2014  0.549
2014 Spinale FG, Villarreal F. Targeting matrix metalloproteinases in heart disease: lessons from endogenous inhibitors. Biochemical Pharmacology. 90: 7-15. PMID 24780447 DOI: 10.1016/J.Bcp.2014.04.011  0.557
2014 Purcell BP, Lobb D, Charati MB, Dorsey SM, Wade RJ, Zellars KN, Doviak H, Pettaway S, Logdon CB, Shuman JA, Freels PD, Gorman JH, Gorman RC, Spinale FG, Burdick JA. Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition. Nature Materials. 13: 653-61. PMID 24681647 DOI: 10.1038/Nmat3922  0.555
2014 Zavadzkas JA, Stroud RE, Bouges S, Mukherjee R, Jones JR, Patel RK, McDermott PJ, Spinale FG. Targeted overexpression of tissue inhibitor of matrix metalloproteinase-4 modifies post-myocardial infarction remodeling in mice. Circulation Research. 114: 1435-45. PMID 24637197 DOI: 10.1161/Circresaha.114.303634  0.563
2014 Kholmukhamedov A, Spinale FG, Mukherjee R, Lemasters JJ. Reply to "letter to the editor: 'cyclosporin A in left ventricular remodeling after myocardial infarction'". American Journal of Physiology. Heart and Circulatory Physiology. 306: H778-9. PMID 24583826 DOI: 10.1152/Ajpheart.00021.2014  0.416
2014 Eckhouse SR, Purcell BP, McGarvey JR, Lobb D, Logdon CB, Doviak H, O'Neill JW, Shuman JA, Novack CP, Zellars KN, Pettaway S, Black RA, Khakoo A, Lee T, Mukherjee R, ... ... Spinale FG, et al. Local hydrogel release of recombinant TIMP-3 attenuates adverse left ventricular remodeling after experimental myocardial infarction. Science Translational Medicine. 6: 223ra21. PMID 24523321 DOI: 10.1126/Scitranslmed.3007244  0.545
2014 Goldsmith EC, Bradshaw AD, Zile MR, Spinale FG. Myocardial fibroblast-matrix interactions and potential therapeutic targets. Journal of Molecular and Cellular Cardiology. 70: 92-9. PMID 24472826 DOI: 10.1016/J.Yjmcc.2014.01.008  0.47
2014 Zile MR, Baicu CF, Stroud RE, Van Laer AO, Jones JA, Patel R, Mukherjee R, Spinale FG. Mechanistic relationship between membrane type-1 matrix metalloproteinase and the myocardial response to pressure overload. Circulation. Heart Failure. 7: 340-50. PMID 24395927 DOI: 10.1161/Circheartfailure.113.000984  0.527
2014 Kholmukhamedov A, Logdon C, Hu J, McKinney RA, Spinale FG, Lemasters JJ, Mukherjee R. Cyclosporin A in left ventricular remodeling after myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 306: H53-9. PMID 24163074 DOI: 10.1152/Ajpheart.00079.2013  0.433
2013 Spinale FG, Zile MR. Integrating the myocardial matrix into heart failure recognition and management. Circulation Research. 113: 725-38. PMID 23989715 DOI: 10.1161/Circresaha.113.300309  0.437
2013 Shuman JA, Zurcher JR, Sapp AA, Burdick JA, Gorman RC, Gorman JH, Goldsmith EC, Spinale FG. Localized targeting of biomaterials following myocardial infarction: a foundation to build on. Trends in Cardiovascular Medicine. 23: 301-11. PMID 23746937 DOI: 10.1016/J.Tcm.2013.04.004  0.364
2013 Spinale FG, Stolen CM. Biomarkers and heart disease: what is translational success? Journal of Cardiovascular Translational Research. 6: 447-8. PMID 23733544 DOI: 10.1007/S12265-013-9477-9  0.325
2013 Mukherjee R, Akar JG, Wharton JM, Adams DK, McClure CD, Stroud RE, Rice AD, DeSantis SM, Spinale FG, Gold MR. Plasma profiles of matrix metalloproteinases and tissue inhibitors of the metalloproteinases predict recurrence of atrial fibrillation following cardioversion. Journal of Cardiovascular Translational Research. 6: 528-35. PMID 23722357 DOI: 10.1007/S12265-013-9471-2  0.491
2013 Janicki JS, Spinale FG, Levick SP. Gender differences in non-ischemic myocardial remodeling: are they due to estrogen modulation of cardiac mast cells and/or membrane type 1 matrix metalloproteinase. PflüGers Archiv : European Journal of Physiology. 465: 687-97. PMID 23417570 DOI: 10.1007/S00424-013-1229-9  0.402
2013 Spinale FG. Epilysin (matrix metalloproteinase-28) joins the matrix metalloproteinase team on the field of postmyocardial infarction remodeling. Circulation Research. 112: 579-82. PMID 23410875 DOI: 10.1161/Circresaha.113.300811  0.542
2013 Spinale FG, Janicki JS, Zile MR. Membrane-associated matrix proteolysis and heart failure. Circulation Research. 112: 195-208. PMID 23287455 DOI: 10.1161/Circresaha.112.266882  0.585
2013 Goldsmith EC, Bradshaw AD, Spinale FG. Cellular mechanisms of tissue fibrosis. 2. Contributory pathways leading to myocardial fibrosis: moving beyond collagen expression. American Journal of Physiology. Cell Physiology. 304: C393-402. PMID 23174564 DOI: 10.1152/Ajpcell.00347.2012  0.51
2013 Eckhouse SR, Akerman AW, Logdon CB, Oelsen JM, O'Quinn EC, Nadeau EK, Stroud RE, Mukherjee R, Jones JA, Spinale FG. Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia-reperfusion: relationship to interstitial microRNA dynamics and myocardial function. The Journal of Thoracic and Cardiovascular Surgery. 145: 267-275, 277.e1-4; d. PMID 23102905 DOI: 10.1016/J.Jtcvs.2012.09.071  0.533
2012 Warren SA, Briggs LE, Zeng H, Chuang J, Chang EI, Terada R, Li M, Swanson MS, Lecker SH, Willis MS, Spinale FG, Maupin-Furlowe J, McMullen JR, Moss RL, Kasahara H. Myosin light chain phosphorylation is critical for adaptation to cardiac stress. Circulation. 126: 2575-88. PMID 23095280 DOI: 10.1161/Circulationaha.112.116202  0.332
2012 Essa EM, Zile MR, Stroud RE, Rice A, Gumina RJ, Leier CV, Spinale FG. Changes in plasma profiles of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in stress-induced cardiomyopathy. Journal of Cardiac Failure. 18: 487-92. PMID 22633307 DOI: 10.1016/J.Cardfail.2012.04.002  0.53
2012 Houser SR, Margulies KB, Murphy AM, Spinale FG, Francis GS, Prabhu SD, Rockman HA, Kass DA, Molkentin JD, Sussman MA, Koch WJ, Koch W. Animal models of heart failure: a scientific statement from the American Heart Association. Circulation Research. 111: 131-50. PMID 22595296 DOI: 10.1161/Res.0B013E3182582523  0.305
2012 Zile MR, Baicu CF, Stroud RE, Van Laer A, Arroyo J, Mukherjee R, Jones JA, Spinale FG. Pressure overload-dependent membrane type 1-matrix metalloproteinase induction: relationship to LV remodeling and fibrosis. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1429-37. PMID 22287584 DOI: 10.1152/Ajpheart.00580.2011  0.559
2012 Spinale FG. Visualizing the RAGE molecular: imaging after MI provides insight into a complex receptor. Jacc. Cardiovascular Imaging. 5: 68-70. PMID 22239895 DOI: 10.1016/J.Jcmg.2011.11.004  0.454
2012 Ikonomidis JS, Ruddy JM, Benton SM, Arroyo J, Brinsa TA, Stroud RE, Zeeshan A, Bavaria JE, Gorman JH, Gorman RC, Spinale FG, Jones JA. Aortic dilatation with bicuspid aortic valves: cusp fusion correlates to matrix metalloproteinases and inhibitors. The Annals of Thoracic Surgery. 93: 457-63. PMID 22206960 DOI: 10.1016/J.Athoracsur.2011.09.057  0.414
2012 Eckhouse SR, Spinale FG. Changes in the myocardial interstitium and contribution to the progression of heart failure. Heart Failure Clinics. 8: 7-20. PMID 22108723 DOI: 10.1016/J.Hfc.2011.08.012  0.462
2012 Yarbrough WM, Mukherjee R, Stroud RE, Rivers WT, Oelsen JM, Dixon JA, Eckhouse SR, Ikonomidis JS, Zile MR, Spinale FG. Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature. The Journal of Thoracic and Cardiovascular Surgery. 143: 215-23. PMID 22056365 DOI: 10.1016/j.jtcvs.2011.09.032  0.383
2012 Yarbrough WM, Mukherjee R, Ikonomidis JS, Zile MR, Spinale FG. Myocardial remodeling with aortic stenosis and after aortic valve replacement: mechanisms and future prognostic implications. The Journal of Thoracic and Cardiovascular Surgery. 143: 656-64. PMID 21762938 DOI: 10.1016/J.Jtcvs.2011.04.044  0.45
2012 Mukherjee R, Snipes JM, Saunders SM, Zavadzkas JA, Spinale FG. Discordant activation of gene promoters for matrix metalloproteinases and tissue inhibitors of the metalloproteinases following myocardial infarction. The Journal of Surgical Research. 172: 59-67. PMID 20863528 DOI: 10.1016/J.Jss.2010.06.015  0.578
2012 Essa EM, Zile MR, Stroud RE, Rice A, Gumina RJ, Leier CV, Spinale FG. Changes in Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of MMPs Plasma Profiles in Stress-Induced Cardiomyopathy Journal of Cardiac Failure. 18: S13. DOI: 10.1016/J.Cardfail.2012.06.041  0.53
2011 Spinale FG. Diversity of myocardial interstitial proteolytic pathways: gene deletion reveals unexpected consequences. Circulation. 124: 2052-5. PMID 22064956 DOI: 10.1161/Circulationaha.111.064071  0.59
2011 Zile MR, Mehurg SM, Arroyo JE, Stroud RE, DeSantis SM, Spinale FG. Relationship between the temporal profile of plasma microRNA and left ventricular remodeling in patients after myocardial infarction. Circulation. Cardiovascular Genetics. 4: 614-9. PMID 21956146 DOI: 10.1161/Circgenetics.111.959841  0.335
2011 Dixon JA, Gorman RC, Stroud RE, Mukherjee R, Meyer EC, Baker NL, Morita M, Hamamoto H, Ryan LP, Gorman JH, Spinale FG. Targeted regional injection of biocomposite microspheres alters post-myocardial infarction remodeling and matrix proteolytic pathways. Circulation. 124: S35-45. PMID 21911817 DOI: 10.1161/Circulationaha.111.035774  0.563
2011 Zavadzkas JA, Mukherjee R, Rivers WT, Patel RK, Meyer EC, Black LE, McKinney RA, Oelsen JM, Stroud RE, Spinale FG. Direct regulation of membrane type 1 matrix metalloproteinase following myocardial infarction causes changes in survival, cardiac function, and remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1656-66. PMID 21666120 DOI: 10.1152/Ajpheart.00141.2011  0.574
2011 Sahul ZH, Mukherjee R, Song J, McAteer J, Stroud RE, Dione DP, Staib L, Papademetris X, Dobrucki LW, Duncan JS, Spinale FG, Sinusas AJ. Targeted imaging of the spatial and temporal variation of matrix metalloproteinase activity in a porcine model of postinfarct remodeling: relationship to myocardial dysfunction. Circulation. Cardiovascular Imaging. 4: 381-91. PMID 21505092 DOI: 10.1161/Circimaging.110.961854  0.531
2011 Reust DL, Dixon JA, McKinney RA, Patel RK, Rivers WT, Mukherjee R, Stroud RE, Madden K, Groves K, Rajopadhye M, Reeves ST, Abernathy JH, Spinale FG. Continuous localized monitoring of plasmin activity identifies differential and regional effects of the serine protease inhibitor aprotinin: relevance to antifibrinolytic therapy. Journal of Cardiovascular Pharmacology. 57: 400-6. PMID 21502925 DOI: 10.1097/Fjc.0B013E31820B7Df1  0.301
2011 Dixon JA, Goodman AM, Gaillard WF, Rivers WT, McKinney RA, Mukherjee R, Baker NL, Ikonomidis JS, Spinale FG. Hemodynamics and myocardial blood flow patterns after placement of a cardiac passive restraint device in a model of dilated cardiomyopathy. The Journal of Thoracic and Cardiovascular Surgery. 142: 1038-45. PMID 21397269 DOI: 10.1016/J.Jtcvs.2010.09.065  0.313
2011 Zile MR, Desantis SM, Baicu CF, Stroud RE, Thompson SB, McClure CD, Mehurg SM, Spinale FG. Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure. Circulation. Heart Failure. 4: 246-56. PMID 21350055 DOI: 10.1161/Circheartfailure.110.958199  0.478
2011 Dixon JA, Spinale FG. Myocardial remodeling: cellular and extracellular events and targets. Annual Review of Physiology. 73: 47-68. PMID 21314431 DOI: 10.1146/Annurev-Physiol-012110-142230  0.345
2011 Hsia TY, Ringewald JM, Stroud RE, Forbus GA, Bradley SM, Chung WK, Spinale FG. Determinants of extracellular matrix remodelling are differentially expressed in paediatric and adult dilated cardiomyopathy. European Journal of Heart Failure. 13: 271-7. PMID 21147820 DOI: 10.1093/Eurjhf/Hfq184  0.531
2011 Hsia TY, Ringewald JM, Stroud RE, Roessler N, Kumar N, Reeves ST, Spinale FG. Plasma profiling determinants of matrix homeostasis in paediatric dilated cardiomyopathy. Cardiology in the Young. 21: 52-61. PMID 20977821 DOI: 10.1017/S1047951110001381  0.47
2010 Ellenbogen KA, Gold MR, Meyer TE, Fernndez Lozano I, Mittal S, Waggoner AD, Lemke B, Singh JP, Spinale FG, Van Eyk JE, Whitehill J, Weiner S, Bedi M, Rapkin J, Stein KM. Primary results from the SmartDelay determined AV optimization: a comparison to other AV delay methods used in cardiac resynchronization therapy (SMART-AV) trial: a randomized trial comparing empirical, echocardiography-guided, and algorithmic atrioventricular delay programming in cardiac resynchronization therapy. Circulation. 122: 2660-8. PMID 21098426 DOI: 10.1161/Circulationaha.110.992552  0.334
2010 Dixon JA, Gaillard WF, Rivers WT, Koval CN, Stroud RE, Mukherjee R, Spinale FG. Heterogeneity in MT1-MMP activity with ischemia-reperfusion and previous myocardial infarction: relation to regional myocardial function. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1947-58. PMID 20935147 DOI: 10.1152/Ajpheart.00314.2010  0.487
2010 Spinale FG, Mukherjee R, Zavadzkas JA, Koval CN, Bouges S, Stroud RE, Dobrucki LW, Sinusas AJ. Cardiac restricted overexpression of membrane type-1 matrix metalloproteinase causes adverse myocardial remodeling following myocardial infarction. The Journal of Biological Chemistry. 285: 30316-27. PMID 20643648 DOI: 10.1074/Jbc.M110.158196  0.593
2010 Spinale FG. Amplified bioactive signaling and proteolytic enzymes following ischemia reperfusion and aging: remodeling pathways that are not like a fine wine. Circulation. 122: 322-4. PMID 20625106 DOI: 10.1161/Circulationaha.110.967414  0.474
2010 Mukherjee R, Rivers WT, Ruddy JM, Matthews RG, Koval CN, Plyler RA, Chang EI, Patel RK, Kern CB, Stroud RE, Spinale FG. Long-term localized high-frequency electric stimulation within the myocardial infarct: effects on matrix metalloproteinases and regional remodeling. Circulation. 122: 20-32. PMID 20566951 DOI: 10.1161/Circulationaha.110.936872  0.531
2010 McQuinn TC, Deardorff RL, Mukherjee R, Taylor AG, Graham EM, Atz AM, Forbus GA, DeSantis SM, Young JB, Stroud RE, Crawford FA, Bradley SM, Reeves ST, Spinale FG. Circulating matrix metalloproteinase levels after ventricular septal defect repair in infants. The Journal of Thoracic and Cardiovascular Surgery. 140: 1257-65. PMID 20561637 DOI: 10.1016/J.Jtcvs.2010.05.014  0.473
2010 Mukherjee R, Colbath GP, Justus CD, Bruce JA, Allen CM, Hewett KW, Saul JP, Gourdie RG, Spinale FG. Spatiotemporal induction of matrix metalloproteinase-9 transcription after discrete myocardial injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3819-28. PMID 20530752 DOI: 10.1096/Fj.10-155531  0.426
2010 Hsia TY, McQuinn TC, Mukherjee R, Deardorff RL, Squires JE, Stroud RE, Crawford FA, Bradley SM, Reeves ST, Spinale FG. Effects of aprotinin or tranexamic acid on proteolytic/cytokine profiles in infants after cardiac surgery. The Annals of Thoracic Surgery. 89: 1843-52; discussion . PMID 20494037 DOI: 10.1016/J.Athoracsur.2010.02.069  0.408
2010 Mukherjee R, Zavadzkas JA, Rivers WT, McLean JE, Chang EI, Bouges S, Matthews RG, Koval CN, Stroud RE, Spinale FG. Short-term disruption in regional left ventricular electrical conduction patterns increases interstitial matrix metalloproteinase activity. American Journal of Physiology. Heart and Circulatory Physiology. 299: H217-24. PMID 20472759 DOI: 10.1152/Ajpheart.00065.2010  0.543
2010 Jones JA, Ruddy JM, Bouges S, Zavadzkas JA, Brinsa TA, Stroud RE, Mukherjee R, Spinale FG, Ikonomidis JS. Alterations in membrane type-1 matrix metalloproteinase abundance after the induction of thoracic aortic aneurysm in a murine model. American Journal of Physiology. Heart and Circulatory Physiology. 299: H114-24. PMID 20418476 DOI: 10.1152/Ajpheart.00028.2010  0.532
2010 Wang G, Hamid T, Keith RJ, Zhou G, Partridge CR, Xiang X, Kingery JR, Lewis RK, Li Q, Rokosh DG, Ford R, Spinale FG, Riggs DW, Srivastava S, Bhatnagar A, et al. Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart. Circulation. 121: 1912-25. PMID 20404253 DOI: 10.1161/Circulationaha.109.905471  0.392
2010 Dixon JA, Spinale FG. Pathophysiology of myocardial injury and remodeling: implications for molecular imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 102S-106S. PMID 20395340 DOI: 10.2967/Jnumed.109.068213  0.394
2010 Shah SA, Spinale FG, Ikonomidis JS, Stroud RE, Chang EI, Reed CE. Differential matrix metalloproteinase levels in adenocarcinoma and squamous cell carcinoma of the lung. The Journal of Thoracic and Cardiovascular Surgery. 139: 984-90; discussion 9. PMID 20304142 DOI: 10.1016/J.Jtcvs.2009.12.016  0.428
2010 Reust DL, Reeves ST, Abernathy JH, Dixon JA, Gaillard WF, Mukherjee R, Koval CN, Stroud RE, Spinale FG. Temporally and regionally disparate differences in plasmin activity by tranexamic acid. Anesthesia and Analgesia. 110: 694-701. PMID 20185649 DOI: 10.1213/Ane.0B013E3181C7Eb27  0.332
2010 Yarbrough WM, Mukherjee R, Stroud RE, Meyer EC, Escobar GP, Sample JA, Hendrick JW, Mingoia JT, Spinale FG. Caspase inhibition modulates left ventricular remodeling following myocardial infarction through cellular and extracellular mechanisms. Journal of Cardiovascular Pharmacology. 55: 408-16. PMID 20147844 DOI: 10.1097/Fjc.0B013E3181D4Ca66  0.403
2010 Toole JM, Ikonomidis JS, Szeto WY, Zellner JL, Mulcahy J, Deardorff RL, Spinale FG. Selective endothelin-1 receptor type A inhibition in subjects undergoing cardiac surgery with preexisting left ventricular dysfunction: Influence on early postoperative hemodynamics. The Journal of Thoracic and Cardiovascular Surgery. 139: 646-54. PMID 20074751 DOI: 10.1016/J.Jtcvs.2009.11.046  0.383
2010 Stein KM, Ellenbogen KA, Gold MR, Lemke B, Lozano IF, Mittal S, Spinale FG, Van Eyk JE, Waggoner AD, Meyer TE. SmartDelay determined AV optimization: a comparison of AV delay methods used in cardiac resynchronization therapy (SMART-AV): rationale and design. Pacing and Clinical Electrophysiology : Pace. 33: 54-63. PMID 19821938 DOI: 10.1111/J.1540-8159.2009.02581.X  0.355
2010 Ruddy JM, Jones JA, Stroud RE, Mukherjee R, Spinale FG, Ikonomidis JS. Differential effect of wall tension on matrix metalloproteinase promoter activation in the thoracic aorta. The Journal of Surgical Research. 160: 333-9. PMID 19375723 DOI: 10.1016/J.Jss.2008.12.033  0.527
2010 Mekkaoui C, Jackowski MP, Martuzzi R, Dione DP, Spinale FG, Sinusas AJ. Regional matrix metalloproteinase activation correlates with microstructure diffusion tensor indices post myocardial infarction Journal of Cardiovascular Magnetic Resonance. 12. DOI: 10.1186/1532-429X-12-S1-P241  0.505
2009 Deardorff R, Spinale FG. Cytokines and matrix metalloproteinases as potential biomarkers in chronic heart failure. Biomarkers in Medicine. 3: 513-523. PMID 20161487 DOI: 10.2217/Bmm.09.60  0.536
2009 Spinale FG, Escobar GP, Mukherjee R, Zavadzkas JA, Saunders SM, Jeffords LB, Leone AM, Beck C, Bouges S, Stroud RE. Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging. Circulation. Heart Failure. 2: 351-60. PMID 19808359 DOI: 10.1161/Circheartfailure.108.844845  0.557
2009 Dixon JA, Spinale FG. Large animal models of heart failure: a critical link in the translation of basic science to clinical practice. Circulation. Heart Failure. 2: 262-71. PMID 19808348 DOI: 10.1161/Circheartfailure.108.814459  0.346
2009 Ruddy JM, Jones JA, Stroud RE, Mukherjee R, Spinale FG, Ikonomidis JS. Differential effects of mechanical and biological stimuli on matrix metalloproteinase promoter activation in the thoracic aorta. Circulation. 120: S262-8. PMID 19752377 DOI: 10.1161/Circulationaha.108.843581  0.512
2009 Dixon JA, Gorman RC, Stroud RE, Bouges S, Hirotsugu H, Gorman JH, Martens TP, Itescu S, Schuster MD, Plappert T, St John-Sutton MG, Spinale FG. Mesenchymal cell transplantation and myocardial remodeling after myocardial infarction. Circulation. 120: S220-9. PMID 19752372 DOI: 10.1161/Circulationaha.108.842302  0.449
2009 Mani SK, Balasubramanian S, Zavadzkas JA, Jeffords LB, Rivers WT, Zile MR, Mukherjee R, Spinale FG, Kuppuswamy D. Calpain inhibition preserves myocardial structure and function following myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1744-51. PMID 19734364 DOI: 10.1152/Ajpheart.00338.2009  0.448
2009 Jones JA, Beck C, Barbour JR, Zavadzkas JA, Mukherjee R, Spinale FG, Ikonomidis JS. Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling. The American Journal of Pathology. 175: 1746-56. PMID 19729479 DOI: 10.2353/Ajpath.2009.081141  0.342
2009 Spinale FG, Wilbur NM. Matrix metalloproteinase therapy in heart failure. Current Treatment Options in Cardiovascular Medicine. 11: 339-46. PMID 19627666 DOI: 10.1007/S11936-009-0034-4  0.582
2009 McEvoy MD, Sabbagh MJ, Taylor AG, Zavadzkas JA, Koval CN, Stroud RE, Ford RL, McLean JE, Reeves ST, Mukherjee R, Spinale FG. Aprotinin modifies left ventricular contractility and cytokine release after ischemia-reperfusion in a dose-dependent manner in a murine model. Anesthesia and Analgesia. 108: 399-406. PMID 19151263 DOI: 10.1213/Ane.0B013E31818Cdb13  0.369
2009 Mehurg S, DeSantis S, Baicu C, Stroud R, Thompson S, McClure C, Koval C, Mulcahy J, Spinale F, Zile M. Effects of Antihypertensive Medications on Proteolytic Determinants of Myocardial Extracellular Matrix Composition in Patients with Hypertensive Heart Disease Journal of Cardiac Failure. 15: S15-S16. DOI: 10.1016/J.Cardfail.2009.06.360  0.441
2008 Sabbagh MJ, Looper JM, Zavadzkas JA, Stroud RE, Ford RL, Rivers WT, Koval CN, McEvoy MD, Reeves ST, Spinale FG. Aprotinin exacerbates left ventricular dysfunction after ischemia/reperfusion in mice lacking tumor necrosis factor receptor I. Journal of Cardiovascular Pharmacology. 52: 355-62. PMID 18841074 DOI: 10.1097/Fjc.0B013E3181893659  0.335
2008 Spinale FG, Koval CN, Deschamps AM, Stroud RE, Ikonomidis JS. Dynamic changes in matrix metalloprotienase activity within the human myocardial interstitium during myocardial arrest and reperfusion. Circulation. 118: S16-23. PMID 18824748 DOI: 10.1161/Circulationaha.108.786640  0.806
2008 Mukherjee R, Zavadzkas JA, Saunders SM, McLean JE, Jeffords LB, Beck C, Stroud RE, Leone AM, Koval CN, Rivers WT, Basu S, Sheehy A, Michal G, Spinale FG. Targeted myocardial microinjections of a biocomposite material reduces infarct expansion in pigs. The Annals of Thoracic Surgery. 86: 1268-76. PMID 18805174 DOI: 10.1016/J.Athoracsur.2008.04.107  0.413
2008 Zavadzkas JA, Plyler RA, Bouges S, Koval CN, Rivers WT, Beck CU, Chang EI, Stroud RE, Mukherjee R, Spinale FG. Cardiac-restricted overexpression of extracellular matrix metalloproteinase inducer causes myocardial remodeling and dysfunction in aging mice. American Journal of Physiology. Heart and Circulatory Physiology. 295: H1394-402. PMID 18689500 DOI: 10.1152/Ajpheart.00346.2008  0.536
2008 McEvoy MD, Taylor AG, Zavadzkas JA, Mains IM, Ford RL, Stroud RE, Jeffords LB, Beck CU, Reeves ST, Spinale FG. Aprotinin exerts differential and dose-dependent effects on myocardial contractility, oxidative stress, and cytokine release after ischemia-reperfusion. The Annals of Thoracic Surgery. 86: 568-75. PMID 18640335 DOI: 10.1016/J.Athoracsur.2008.04.025  0.339
2008 Dorman BH, Stroud RE, Wyckoff MM, Zellner JL, Botta D, Leonardi AH, Ikonomidis JS, Spinale FG. Differential effects of epsilon-aminocaproic acid and aprotinin on matrix metalloproteinase release in patients following cardiopulmonary bypass. Journal of Cardiovascular Pharmacology. 51: 418-23. PMID 18427286 DOI: 10.1097/Fjc.0B013E318168400A  0.45
2008 Haddad GE, Saunders LJ, Crosby SD, Carles M, del Monte F, King K, Bristow MR, Spinale FG, Macgillivray TE, Semigran MJ, Dec GW, Williams SA, Hajjar RJ, Gwathmey JK. Human cardiac-specific cDNA array for idiopathic dilated cardiomyopathy: sex-related differences. Physiological Genomics. 33: 267-77. PMID 18303083 DOI: 10.1152/Physiolgenomics.00265.2007  0.302
2008 Yan AT, Yan RT, Spinale FG, Afzal R, Gunasinghe HR, Stroud RE, McKelvie RS, Liu PP. Relationships between plasma levels of matrix metalloproteinases and neurohormonal profile in patients with heart failure. European Journal of Heart Failure. 10: 125-8. PMID 18234554 DOI: 10.1016/j.ejheart.2007.12.002  0.363
2008 Beeri R, Yosefy C, Guerrero JL, Nesta F, Abedat S, Chaput M, del Monte F, Handschumacher MD, Stroud R, Sullivan S, Pugatsch T, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, et al. Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation. Journal of the American College of Cardiology. 51: 476-86. PMID 18222360 DOI: 10.1016/J.Jacc.2007.07.093  0.493
2008 Deschamps AM, Zavadzkas J, Murphy RL, Koval CN, McLean JE, Jeffords L, Saunders SM, Sheats NJ, Stroud RE, Spinale FG. Interruption of endothelin signaling modifies membrane type 1 matrix metalloproteinase activity during ischemia and reperfusion. American Journal of Physiology. Heart and Circulatory Physiology. 294: H875-83. PMID 18065523 DOI: 10.1152/Ajpheart.00918.2007  0.78
2007 Spinale FG. Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function. Physiological Reviews. 87: 1285-342. PMID 17928585 DOI: 10.1152/Physrev.00012.2007  0.591
2007 McEvoy MD, Reeves ST, Reves JG, Spinale FG. Aprotinin in cardiac surgery: a review of conventional and novel mechanisms of action. Anesthesia and Analgesia. 105: 949-62. PMID 17898372 DOI: 10.1213/01.Ane.0000281936.04102.9F  0.307
2007 Beeri R, Yosefy C, Guerrero JL, Abedat S, Handschumacher MD, Stroud RE, Sullivan S, Chaput M, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA. Early repair of moderate ischemic mitral regurgitation reverses left ventricular remodeling: a functional and molecular study. Circulation. 116: I288-93. PMID 17846319 DOI: 10.1161/Circulationaha.106.681114  0.417
2007 Bonnema DD, Webb CS, Pennington WR, Stroud RE, Leonardi AE, Clark LL, McClure CD, Finklea L, Spinale FG, Zile MR. Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs). Journal of Cardiac Failure. 13: 530-40. PMID 17826643 DOI: 10.1016/J.Cardfail.2007.04.010  0.521
2007 Spruill LS, Lowry AS, Stroud RE, Squires CE, Mains IM, Flack EC, Beck C, Ikonomidis JS, Crumbley AJ, McDermott PJ, Spinale FG. Membrane-type-1 matrix metalloproteinase transcription and translation in myocardial fibroblasts from patients with normal left ventricular function and from patients with cardiomyopathy. American Journal of Physiology. Cell Physiology. 293: C1362-73. PMID 17670887 DOI: 10.1152/Ajpcell.00545.2006  0.554
2007 Ikonomidis JS, Jones JA, Barbour JR, Stroud RE, Clark LL, Kaplan BS, Zeeshan A, Bavaria JE, Gorman JH, Spinale FG, Gorman RC. Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves. The Journal of Thoracic and Cardiovascular Surgery. 133: 1028-36. PMID 17382648 DOI: 10.1016/J.Jtcvs.2006.10.083  0.305
2007 Barbour JR, Spinale FG, Ikonomidis JS. Proteinase systems and thoracic aortic aneurysm progression. The Journal of Surgical Research. 139: 292-307. PMID 17292415 DOI: 10.1016/J.Jss.2006.09.020  0.474
2007 Mani S, Balasubramanian S, Baicu CF, Van Laer AO, Mukherjee RD, Zavadzkas JA, Spinale FG, Zile MR, Kuppuswamy D. Calpain Inhibition Preserves Ventricular Structure and Function in Two Distinct Cardiomyopathic Models Journal of Cardiac Failure. 13: S93. DOI: 10.1016/J.Cardfail.2007.06.366  0.337
2006 Barbour JR, Stroud RE, Lowry AS, Clark LL, Leone AM, Jones JA, Spinale FG, Ikonomidis JS. Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation. The Journal of Thoracic and Cardiovascular Surgery. 132: 788-95. PMID 17000289 DOI: 10.1016/J.Jtcvs.2006.05.052  0.427
2006 Yan AT, Yan RT, Spinale FG, Afzal R, Gunasinghe HR, Arnold M, Demers C, McKelvie RS, Liu PP. Plasma matrix metalloproteinase-9 level is correlated with left ventricular volumes and ejection fraction in patients with heart failure. Journal of Cardiac Failure. 12: 514-9. PMID 16952784 DOI: 10.1016/J.Cardfail.2006.05.012  0.565
2006 Webb CS, Bonnema DD, Ahmed SH, Leonardi AH, McClure CD, Clark LL, Stroud RE, Corn WC, Finklea L, Zile MR, Spinale FG. Specific temporal profile of matrix metalloproteinase release occurs in patients after myocardial infarction: relation to left ventricular remodeling. Circulation. 114: 1020-7. PMID 16923753 DOI: 10.1161/Circulationaha.105.600353  0.596
2006 Apple KA, McLean JE, Squires CE, Schaeffer B, Sample JA, Murphy RL, Deschamps AM, Leonardi AH, Allen CM, Hendrick JW, Stroud RE, Mukherjee R, Spinale FG. Differential effects of protein kinase C isoform activation in endothelin-mediated myocyte contractile dysfunction with cardioplegic arrest and reperfusion. The Annals of Thoracic Surgery. 82: 664-71. PMID 16863782 DOI: 10.1016/J.Athoracsur.2006.03.021  0.695
2006 Ikonomidis JS, Jones JA, Barbour JR, Stroud RE, Clark LL, Kaplan BS, Zeeshan A, Bavaria JE, Gorman JH, Spinale FG, Gorman RC. Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with Marfan syndrome. Circulation. 114: I365-70. PMID 16820601 DOI: 10.1161/Circulationaha.105.000810  0.404
2006 Lindsey ML, Escobar GP, Mukherjee R, Goshorn DK, Sheats NJ, Bruce JA, Mains IM, Hendrick JK, Hewett KW, Gourdie RG, Matrisian LM, Spinale FG. Matrix metalloproteinase-7 affects connexin-43 levels, electrical conduction, and survival after myocardial infarction. Circulation. 113: 2919-28. PMID 16769909 DOI: 10.1161/Circulationaha.106.612960  0.569
2006 Mukherjee R, Mingoia JT, Bruce JA, Austin JS, Stroud RE, Escobar GP, McClister DM, Allen CM, Alfonso-Jaume MA, Fini ME, Lovett DH, Spinale FG. Selective spatiotemporal induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 transcription after myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2216-28. PMID 16766634 DOI: 10.1152/Ajpheart.01343.2005  0.57
2006 Spinale FG, Escobar GP, Hendrick JW, Clark LL, Camens SS, Mingoia JP, Squires CG, Stroud RE, Ikonomidis JS. Chronic matrix metalloproteinase inhibition following myocardial infarction in mice: differential effects on short and long-term survival. The Journal of Pharmacology and Experimental Therapeutics. 318: 966-73. PMID 16757539 DOI: 10.1124/Jpet.106.104455  0.485
2006 Ahmed SH, Clark LL, Pennington WR, Webb CS, Bonnema DD, Leonardi AH, McClure CD, Spinale FG, Zile MR. Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease. Circulation. 113: 2089-96. PMID 16636176 DOI: 10.1161/Circulationaha.105.573865  0.525
2006 Flack EC, Lindsey ML, Squires CE, Kaplan BS, Stroud RE, Clark LL, Escobar PG, Yarbrough WM, Spinale FG. Alterations in cultured myocardial fibroblast function following the development of left ventricular failure. Journal of Molecular and Cellular Cardiology. 40: 474-83. PMID 16516916 DOI: 10.1016/J.Yjmcc.2006.01.019  0.523
2006 Apple KA, Yarbrough WM, Mukherjee R, Deschamps AM, Escobar PG, Mingoia JT, Sample JA, Hendrick JW, Dowdy KB, McLean JE, Stroud RE, O'Neill TP, Spinale FG. Selective targeting of matrix metalloproteinase inhibition in post-infarction myocardial remodeling. Journal of Cardiovascular Pharmacology. 47: 228-35. PMID 16495760 DOI: 10.1097/01.Fjc.0000200989.23987.B8  0.816
2006 Mukherjee R, Herron AR, Lowry AS, Stroud RE, Stroud MR, Wharton JM, Ikonomidis JS, Crumbley AJ, Spinale FG, Gold MR. Selective induction of matrix metalloproteinases and tissue inhibitor of metalloproteinases in atrial and ventricular myocardium in patients with atrial fibrillation. The American Journal of Cardiology. 97: 532-7. PMID 16461051 DOI: 10.1016/J.Amjcard.2005.08.073  0.546
2006 Newby AC, Pauschinger M, Spinale FG. From tadpole tails to transgenic mice: metalloproteinases have brought about a metamorphosis in our understanding of cardiovascular disease. Cardiovascular Research. 69: 559-61. PMID 16427036 DOI: 10.1016/J.Cardiores.2005.12.011  0.488
2006 Deschamps AM, Spinale FG. Pathways of matrix metalloproteinase induction in heart failure: bioactive molecules and transcriptional regulation. Cardiovascular Research. 69: 666-76. PMID 16426590 DOI: 10.1016/J.Cardiores.2005.10.004  0.804
2006 Blom AS, Pilla JJ, Gorman RC, Gorman JH, Mukherjee R, Spinale FG, Acker MA. Infarct size reduction and attenuation of global left ventricular remodeling with the CorCap cardiac support device following acute myocardial infarction in sheep. Heart Failure Reviews. 10: 125-39. PMID 16258720 DOI: 10.1007/S10741-005-4640-2  0.437
2006 Lindsey ML, Escobar GP, Dobrucki LW, Goshorn DK, Bouges S, Mingoia JT, McClister DM, Su H, Gannon J, MacGillivray C, Lee RT, Sinusas AJ, Spinale FG. Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 290: H232-9. PMID 16126817 DOI: 10.1152/Ajpheart.00457.2005  0.552
2005 Su H, Spinale FG, Dobrucki LW, Song J, Hua J, Sweterlitsch S, Dione DP, Cavaliere P, Chow C, Bourke BN, Hu XY, Azure M, Yalamanchili P, Liu R, Cheesman EH, et al. Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling Circulation.. 112: 3157-3167. PMID 16275862 DOI: 10.1161/CIRCULATIONAHA.105.583021  0.462
2005 Ikonomidis JS, Barbour JR, Amani Z, Stroud RE, Herron AR, McClister DM, Camens SE, Lindsey ML, Mukherjee R, Spinale FG. Effects of deletion of the matrix metalloproteinase 9 gene on development of murine thoracic aortic aneurysms. Circulation. 112: I242-8. PMID 16159824 DOI: 10.1161/Circulationaha.104.526152  0.503
2005 Blom AS, Mukherjee R, Pilla JJ, Lowry AS, Yarbrough WM, Mingoia JT, Hendrick JW, Stroud RE, McLean JE, Affuso J, Gorman RC, Gorman JH, Acker MA, Spinale FG. Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction. Circulation. 112: 1274-83. PMID 16129812 DOI: 10.1161/Circulationaha.104.499202  0.437
2005 Deschamps AM, Spinale FG. Disruptions and detours in the myocardial matrix highway and heart failure. Current Heart Failure Reports. 2: 10-7. PMID 16036046 DOI: 10.1007/S11897-005-0002-6  0.785
2005 Deschamps AM, Spinale FG. Matrix modulation and heart failure: new concepts question old beliefs. Current Opinion in Cardiology. 20: 211-6. PMID 15861009 DOI: 10.1097/01.Hco.0000162397.44843.83  0.784
2005 Deschamps AM, Apple KA, Leonardi AH, McLean JE, Yarbrough WM, Stroud RE, Clark LL, Sample JA, Spinale FG. Myocardial interstitial matrix metalloproteinase activity is altered by mechanical changes in LV load: interaction with the angiotensin type 1 receptor. Circulation Research. 96: 1110-8. PMID 15860759 DOI: 10.1161/01.Res.0000167830.12010.6B  0.806
2005 Lindsey ML, Goshorn DK, Squires CE, Escobar GP, Hendrick JW, Mingoia JT, Sweterlitsch SE, Spinale FG. Age-dependent changes in myocardial matrix metalloproteinase/tissue inhibitor of metalloproteinase profiles and fibroblast function. Cardiovascular Research. 66: 410-9. PMID 15820210 DOI: 10.1016/j.cardiores.2004.11.029  0.466
2005 Multani MM, Ikonomidis JS, Kim PY, Miller EA, Payne KJ, Mukherjee R, Dorman BH, Spinale FG. Dynamic and differential changes in myocardial and plasma endothelin in patients undergoing cardiopulmonary bypass. The Journal of Thoracic and Cardiovascular Surgery. 129: 584-90. PMID 15746742 DOI: 10.1016/J.Jtcvs.2004.07.018  0.403
2005 Stroud RE, Deschamps AM, Lowry AS, Hardin AE, Mukherjee R, Lindsey ML, Ramamoorthy S, Zile MR, Spencer WH, Spinale FG. Plasma monitoring of the myocardial specific tissue inhibitor of metalloproteinase-4 after alcohol septal ablation in hypertrophic obstructive cardiomyopathy. Journal of Cardiac Failure. 11: 124-30. PMID 15732032 DOI: 10.1016/J.Cardfail.2004.05.002  0.765
2005 Deschamps AM, Yarbrough WM, Squires CE, Allen RA, McClister DM, Dowdy KB, McLean JE, Mingoia JT, Sample JA, Mukherjee R, Spinale FG. Trafficking of the membrane type-1 matrix metalloproteinase in ischemia and reperfusion: relation to interstitial membrane type-1 matrix metalloproteinase activity. Circulation. 111: 1166-74. PMID 15723986 DOI: 10.1161/01.Cir.0000157149.71297.3A  0.787
2005 Ikonomidis JS, Hendrick JW, Parkhurst AM, Herron AR, Escobar PG, Dowdy KB, Stroud RE, Hapke E, Zile MR, Spinale FG. Accelerated LV remodeling after myocardial infarction in TIMP-1-deficient mice: effects of exogenous MMP inhibition. American Journal of Physiology. Heart and Circulatory Physiology. 288: H149-58. PMID 15598866 DOI: 10.1152/Ajpheart.00370.2004  0.522
2005 Spinale FG. Cell-matrix signaling and thrombospondin: another link to myocardial matrix remodeling. Circulation Research. 95: 446-8. PMID 15345666 DOI: 10.1161/01.Res.0000142315.88477.42  0.415
2005 DOBRUCKI L, LINDSEY M, SONG J, ESCOBAR G, SU H, BOURKE B, MENDIZABAL M, SPINALE F, SINUSAS A. Matrix metalloproteinase-9 gene deletion enhances angiogenesis following myocardial infarction Journal of Nuclear Cardiology. 12: S15-S15. DOI: 10.1016/J.Nuclcard.2004.12.161  0.488
2005 Barbour JR, McClister D, Mukherjee R, Spinale F, Ikonomidis J. Temporal patterns of matrix metalloproteinase-9 gene promoter induction and protein synthesis during thoracic aortic aneurysm progression Journal of the American College of Surgeons. 201: S99. DOI: 10.1016/J.Jamcollsurg.2005.06.232  0.466
2005 Lindsey ML, Spinale FG. Targeting matrix remodeling in cardiac hypertrophy and heart failure Drug Discovery Today: Therapeutic Strategies. 2: 253-258. DOI: 10.1016/J.Ddstr.2005.08.001  0.523
2005 Spinale FG. ACE Inhibition and the AT-1 Receptor: New Targets and Strategies in Heart Failure Journal of Cardiac Failure. 11: S238. DOI: 10.1016/J.Cardfail.2005.08.025  0.326
2005 Yarbrough WM, Spinale FG. MCC-135 Diminishes the Egress of CK-MB but Not of Troponin-I From Cardiomyocytes During Reperfusion: Reply The Annals of Thoracic Surgery. 79: 1095. DOI: 10.1016/J.Athoracsur.2004.03.066  0.34
2005 CLARK L, BONNEMA D, AHMED S, HARDIN A, FINKLEA L, MCCLURE C, LACKLAND D, ZILE M, SPINALE F. Temporal plasma profiles of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in patients with left ventricular hypertrophy American Journal of Hypertension. 18: A120-A120. DOI: 10.1016/J.Amjhyper.2005.03.333  0.507
2004 Yarbrough WM, Mukherjee R, Squires CE, Reese ES, Leiser JS, Stroud RE, Sample JA, Hendrick JW, Mingoia JT, McLean JE, Hardin AE, Dowdy KB, Spinale FG. Caspase inhibition attenuates contractile dysfunction following cardioplegic arrest and rewarming in the setting of left ventricular failure. Journal of Cardiovascular Pharmacology. 44: 645-50. PMID 15550782 DOI: 10.1097/00005344-200412000-00004  0.406
2004 Wilson EM, Diwan A, Spinale FG, Mann DL. Duality of innate stress responses in cardiac injury, repair, and remodeling. Journal of Molecular and Cellular Cardiology. 37: 801-11. PMID 15380670 DOI: 10.1016/J.Yjmcc.2004.05.028  0.343
2004 Ikonomidis JS, Gibson WC, Butler JE, McClister DM, Sweterlitsch SE, Thompson RP, Mukherjee R, Spinale FG. Effects of deletion of the tissue inhibitor of matrix metalloproteinases-1 gene on the progression of murine thoracic aortic aneurysms. Circulation. 110: II268-73. PMID 15364874 DOI: 10.1161/01.Cir.0000138384.68947.20  0.424
2004 Garner JR, Stroud RE, Finklea L, Ikonomidis JS, Dorman BH, Spinale FG. The effects of leukocyte reduction on matrix metalloproteinase release in cardiopulmonary bypass. The Journal of Extra-Corporeal Technology. 36: 185-90. PMID 15334764  0.414
2004 Mukherjee R, Yarbrough WM, Reese ES, Leiser JS, Sample JA, Mingoia JT, Hardin AE, Stroud RE, McLean JE, Hendrick JW, Spinale FG. Myocyte contractility with caspase inhibition and simulated hyperkalemic cardioplegic arrest. The Annals of Thoracic Surgery. 77: 1684-9; discussion 1. PMID 15111166 DOI: 10.1016/J.Athoracsur.2003.10.054  0.331
2004 Spinale FG. Matrix metalloproteinase gene polymorphisms in heart failure: new pieces to the myocardial matrix puzzle. European Heart Journal. 25: 631-3. PMID 15084366 DOI: 10.1016/J.Ehj.2004.02.025  0.496
2004 Diwan A, Dibbs Z, Nemoto S, DeFreitas G, Carabello BA, Sivasubramanian N, Wilson EM, Spinale FG, Mann DL. Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes. Circulation. 109: 262-8. PMID 14699008 DOI: 10.1161/01.Cir.0000109642.27985.Fa  0.327
2004 Chapman RE, Spinale FG. Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1-H10. PMID 14684355 DOI: 10.1152/Ajpheart.00609.2003  0.437
2004 Mukherjee R, Parkhurst AM, Mingoia JT, Sweterlitsch SE, Leiser JS, Escobar GP, Spinale FG, Saul JP. Myocardial remodeling after discrete radiofrequency injury: effects of tissue inhibitor of matrix metalloproteinase-1 gene deletion. American Journal of Physiology. Heart and Circulatory Physiology. 286: H1242-7. PMID 14630637 DOI: 10.1152/Ajpheart.00437.2003  0.519
2004 Spinale FG, Peterson JT. Introduction to special issue on the matrix metalloproteinases: New insights into myocardial remodeling Heart Failure Reviews. 9: 5-6. DOI: 10.1023/B:Hrev.0000011560.81651.Df  0.519
2004 Yan RT, Yan AT, Gunasinghe HR, Liu PP, Spinale FG, McKelvie RS. 1087-103 Plasma metalloproteinase levels are correlated with natriuretic peptide and endothelin-1 levels in patients with heart failure Journal of the American College of Cardiology. 43: A188. DOI: 10.1016/S0735-1097(04)90798-X  0.324
2004 Mukherjee R, Lowry AS, Hardin AE, Stroud MR, Ikonomidis JS, Wharton J, Spinale FG, Gold MR. 1014-225 Myocardial and plasma levels of matrix metalloproteinase-9 are increased with atrial fibrillation Journal of the American College of Cardiology. 43: A106-A107. DOI: 10.1016/S0735-1097(04)90443-3  0.46
2004 Ahmed S, Pennington WR, Clark LL, Hardin AE, McClure C, Webb CS, Finklea L, Spinale FG, Zile MR. Hypertensive hypertrophy: relation between left ventricular (LV) structure/function and matrix metalloproteinases (MMP)/tissue inhibitors of metalloproteinases (TIMP) Journal of Cardiac Failure. 10: S44. DOI: 10.1016/J.Cardfail.2004.06.091  0.489
2003 Yarbrough WM, Mukherjee R, Escobar GP, Sample JA, McLean JE, Dowdy KB, Hendrick JW, Gibson WC, Hardin AE, Mingoia JT, White PC, Stiko A, Armstrong RC, Crawford FA, Spinale FG. Pharmacologic inhibition of intracellular caspases after myocardial infarction attenuates left ventricular remodeling: a potentially novel pathway. The Journal of Thoracic and Cardiovascular Surgery. 126: 1892-9. PMID 14688702 DOI: 10.1016/J.Jtcvs.2003.08.012  0.414
2003 Yarbrough WM, Mukherjee R, Escobar GP, Hendrick JW, Sample JA, Dowdy KB, McLean JE, Mingoia JT, Crawford FA, Spinale FG. Modulation of calcium transport improves myocardial contractility and enzyme profiles after prolonged ischemia-reperfusion. The Annals of Thoracic Surgery. 76: 2054-61; discussion . PMID 14667641 DOI: 10.1016/S0003-4975(03)01059-2  0.325
2003 Yarbrough WM, Mukherjee R, Escobar GP, Mingoia JT, Sample JA, Hendrick JW, Dowdy KB, McLean JE, Stroud RE, Spinale FG. Direct inhibition of the sodium/hydrogen exchanger after prolonged regional ischemia improves contractility on reperfusion independent of myocardial viability. The Journal of Thoracic and Cardiovascular Surgery. 126: 1489-97. PMID 14666024 DOI: 10.1016/S0022-5223(03)00811-0  0.361
2003 Yarbrough WM, Mukherjee R, Escobar GP, Mingoia JT, Sample JA, Hendrick JW, Dowdy KB, McLean JE, Lowry AS, O'Neill TP, Spinale FG. Selective targeting and timing of matrix metalloproteinase inhibition in post-myocardial infarction remodeling. Circulation. 108: 1753-9. PMID 12975256 DOI: 10.1161/01.Cir.0000091087.78630.79  0.584
2003 Lindsey ML, Mann DL, Entman ML, Spinale FG. Extracellular matrix remodeling following myocardial injury. Annals of Medicine. 35: 316-26. PMID 12952018 DOI: 10.1080/07853890310001285  0.586
2003 Dibbs ZI, Diwan A, Nemoto S, DeFreitas G, Abdellatif M, Carabello BA, Spinale FG, Feuerstein G, Sivasubramanian N, Mann DL. Targeted overexpression of transmembrane tumor necrosis factor provokes a concentric cardiac hypertrophic phenotype. Circulation. 108: 1002-8. PMID 12912811 DOI: 10.1161/01.Cir.0000085203.46621.F4  0.305
2003 Wilson EM, Moainie SL, Baskin JM, Lowry AS, Deschamps AM, Mukherjee R, Guy TS, St John-Sutton MG, Gorman JH, Edmunds LH, Gorman RC, Spinale FG. Region- and type-specific induction of matrix metalloproteinases in post-myocardial infarction remodeling. Circulation. 107: 2857-63. PMID 12771000 DOI: 10.1161/01.Cir.0000068375.40887.Fa  0.803
2003 Gunasinghe SK, Ikonomidis J, Spinale FG. Contributory role of matrix metalloproteinases in cardiovascular remodeling. Current Drug Targets. Cardiovascular & Haematological Disorders. 1: 75-91. PMID 12769658 DOI: 10.2174/1568006013337953  0.472
2003 Chapman RE, Scott AA, Deschamps AM, Lowry AS, Stroud RE, Ikonomidis JS, Spinale FG. Matrix metalloproteinase abundance in human myocardial fibroblasts: effects of sustained pharmacologic matrix metalloproteinase inhibition. Journal of Molecular and Cellular Cardiology. 35: 539-48. PMID 12738235 DOI: 10.1016/S0022-2828(03)00077-4  0.807
2003 Yarbrough WM, Mukherjee R, Brinsa TA, Dowdy KB, Scott AA, Escobar GP, Joffs C, Lucas DG, Crawford FA, Spinale FG. Matrix metalloproteinase inhibition modifies left ventricular remodeling after myocardial infarction in pigs. The Journal of Thoracic and Cardiovascular Surgery. 125: 602-10. PMID 12658202 DOI: 10.1067/Mtc.2003.197  0.563
2003 King MK, Coker ML, Goldberg A, McElmurray JH, Gunasinghe HR, Mukherjee R, Zile MR, O'Neill TP, Spinale FG. Selective matrix metalloproteinase inhibition with developing heart failure: Effects on left ventricular function and structure Circulation Research. 92: 177-185. PMID 12574145 DOI: 10.1161/01.Res.0000052312.41419.55  0.811
2003 Yarbrough WM, Spinale FG. Large animal models of congestive heart failure: a critical step in translating basic observations into clinical applications. Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology. 10: 77-86. PMID 12569335 DOI: 10.1067/Mnc.2003.16  0.38
2003 Mukherjee R, Brinsa TA, Dowdy KB, Scott AA, Baskin JM, Deschamps AM, Lowry AS, Escobar GP, Lucas DG, Yarbrough WM, Zile MR, Spinale FG. Myocardial infarct expansion and matrix metalloproteinase inhibition. Circulation. 107: 618-25. PMID 12566376 DOI: 10.1161/01.Cir.0000046449.36178.00  0.82
2003 Spinale FG. The extracellular matrix: summation. Journal of Cardiac Failure. 8: S349-50. PMID 12555144 DOI: 10.1054/Jcaf.2002.129257  0.511
2003 Baicu CF, Stroud JD, Livesay VA, Hapke E, Holder J, Spinale FG, Zile MR. Changes in extracellular collagen matrix alter myocardial systolic performance. American Journal of Physiology. Heart and Circulatory Physiology. 284: H122-32. PMID 12485818 DOI: 10.1152/Ajpheart.00233.2002  0.486
2003 Creemers EE, Davis JN, Parkhurst AM, Leenders P, Dowdy KB, Hapke E, Hauet AM, Escobar PG, Cleutjens JP, Smits JF, Daemen MJ, Zile MR, Spinale FG. Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice. American Journal of Physiology. Heart and Circulatory Physiology. 284: H364-71. PMID 12388239 DOI: 10.1152/Ajpheart.00511.2002  0.55
2003 Yarbrough WM, Reese ES, Leiser JS, Multani MM, Hardin AR, McLean JE, Sample JA, Stroud RE, Hendrick JW, Mukherjee R, Spinale FG. Effects of caspase inhibition on left ventricular myocyte contractile function following cardioplegic arrest and rewarming in a model of pacing induced heart failure Journal of Cardiac Failure. 9: S45. DOI: 10.1016/S1071-9164(03)00514-1  0.397
2003 Yarbrough WM, Mukherjee R, Escobar G, Sample JA, McLean JE, Hendrick JW, White PC, Stiko A, Armstrong RA, Spinale FG. Effects of caspase inhibition on left ventricular dilation following myocardial infarction Journal of Cardiac Failure. 9: S32. DOI: 10.1016/S1071-9164(03)00457-3  0.432
2003 Squires CE, Escobar G, Chapman R, Hendrick JW, Sample JA, Sweterlitsch SE, Mingoia JT, Spinale FG, Lindsey ML. Functional alterations in myocardial fibroblasts from ischemic myocardium Journal of Cardiac Failure. 9: S32. DOI: 10.1016/S1071-9164(03)00456-1  0.382
2003 Chapman R, Lindsey ML, Squires C, Yarbrough WM, Leiser JS, Gardner KC, Reese ES, Butler JE, Spinale FG. Alterations in Myocardial Fibroblast Adhesion in Left Ventricular Remodeling and Failure Journal of Cardiac Failure. 9: S31. DOI: 10.1016/S1071-9164(03)00452-4  0.466
2003 Zile MR, Pennington WR, Hardin A, McClure C, Mukherjee R, Spinale FG. Time dependent changes in plasma matrix metalloproteinase (MMP) and tissue inhibitor of MMP in patients with hypertensive left ventricular hypertrophy Journal of Cardiac Failure. 9: S27. DOI: 10.1016/S1071-9164(03)00426-3  0.544
2003 Yarbrough WM, Sample JA, Mukherjee R, McLean JE, Hendrick JW, Escobar G, Dowdy KB, Mingoia JT, O'Neill TP, Spinale FG. Selective inhibition of matrix metalloproteinase species favorably modifies left ventricular remodeling post myocardial infarction Journal of Cardiac Failure. 9: S26. DOI: 10.1016/S1071-9164(03)00416-0  0.531
2003 Lowry AS, Yarbrough WM, Mukherjee R, Allen RA, Deschamps AM, Escobar G, Sample JA, Hendrick JW, Spinale FG. Selective targeting of matrix metalloproteinase (MMP) inhibition reduces myocardial MMP activity and LV remodeling post myocardial infarction Journal of Cardiac Failure. 9: S26. DOI: 10.1016/S1071-9164(03)00413-5  0.812
2003 Stroud RE, Garner JR, Finklea LM, Ikonomidis JS, Sistino JJ, Dorman B, Spinale FG. Myocardial specific release of matrix metalloproteinases in patients following cardioplegic arrest Journal of Cardiac Failure. 9: S48. DOI: 10.1016/S1071-9164(03)00282-3  0.464
2003 Deschamps AM, Yarbrough WM, Allen RA, Dowdy KB, McLean JE, Mingoia JT, Sample JA, Mukherjee R, Spinale FG. The discordance between localized induction of membrane type-MMPS and tissue inhibitors with ischemia and reperfusion: a potential therapeutic target Journal of Cardiac Failure. 9: S14. DOI: 10.1016/S1071-9164(03)00262-8  0.732
2003 Pennington WR, Hardin A, McClure C, Mukherjee R, Zile MR, Spinale FG. Plasma matrix metalloproteinase and tissue inhibitor of MMP in left ventricular hypertrophy Journal of Cardiac Failure. 9: S13. DOI: 10.1016/S1071-9164(03)00258-6  0.539
2003 Mukherjee R, Reese ES, Multani MM, Yarbrough WM, Dowdy KB, Mingoia JT, Hendrick JW, Stroud RE, Hardin AE, McLean JE, Leiser JS, Blom AS, Pilla JJ, Affuso J, Acker MA, ... Spinale FG, et al. Passive restraint following myocardial infarction modifies left ventricular and myocyte remodeling and improves isolated myocyte contractile response Journal of Cardiac Failure. 9: S10. DOI: 10.1016/S1071-9164(03)00216-1  0.437
2003 Diwan A, Wilson EM, Parkhurst AM, Escobar P, Hendrik JW, Dowdy KB, Lowry AS, Holder JR, Lee-Jackson D, Spinale FG, Mann DL. Matrix metalloproteinase inhibition in transgenic mice with modified cardiac restricted tumor necrosis factor expression: Effects on left ventricular geometry and function Journal of the American College of Cardiology. 41: 170. DOI: 10.1016/S0735-1097(03)81831-4  0.462
2002 Spinale FG, Gunasinghe H, Sprunger PD, Baskin JM, Bradham WC. Extracellular degradative pathways in myocardial remodeling and progression to heart failure. Journal of Cardiac Failure. 8: S332-8. PMID 12555141 DOI: 10.1054/Jcaf.2002.129259  0.608
2002 Wilson EM, Gunasinghe HR, Coker ML, Sprunger P, Lee-Jackson D, Bozkurt B, Deswal A, Mann DL, Spinale FG. Plasma matrix metalloproteinase and inhibitor profiles in patients with heart failure. Journal of Cardiac Failure. 8: 390-8. PMID 12528092 DOI: 10.1054/Jcaf.2002.129659  0.819
2002 Bradham WS, Gunasinghe H, Holder JR, Multani M, Killip D, Anderson M, Meyer D, Spencer WH, Torre-Amione G, Spinale FG. Release of matrix metalloproteinases following alcohol septal ablation in hypertrophic obstructive cardiomyopathy. Journal of the American College of Cardiology. 40: 2165-73. PMID 12505230 DOI: 10.1016/S0735-1097(02)02595-0  0.504
2002 Mukherjee R, Multani MM, Sample JA, Dowdy KB, Zellner JL, Hoover DB, Spinale FG. Effects of adrenomedullin on human myocyte contractile function and beta-adrenergic response. Journal of Cardiovascular Pharmacology and Therapeutics. 7: 235-40. PMID 12490969 DOI: 10.1177/107424840200700406  0.332
2002 Spinale FG. Bioactive peptide signaling within the myocardial interstitium and the matrix metalloproteinases. Circulation Research. 91: 1082-4. PMID 12480806 DOI: 10.1161/01.Res.0000047874.80576.5A  0.499
2002 Spinale FG. The bioactive peptide endothelin causes multiple biologic responses relevant to myocardial and vascular performance after cardiac surgery. The Journal of Thoracic and Cardiovascular Surgery. 123: 1031-4. PMID 12063447 DOI: 10.1067/Mtc.2002.124668  0.351
2002 Lucas DG, Hendrick JW, Sample JA, Mukherjee R, Escobar GP, Smits GJ, Crawford FA, Spinale FG. Cardiorenal effects of adenosine subtype 1 (A1) receptor inhibition in an experimental model of heart failure. Journal of the American College of Surgeons. 194: 603-9. PMID 12022600 DOI: 10.1016/S1072-7515(02)01136-5  0.355
2002 Stroud JD, Baicu CF, Barnes MA, Spinale FG, Zile MR. Viscoelastic properties of pressure overload hypertrophied myocardium: effect of serine protease treatment. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2324-35. PMID 12003843 DOI: 10.1152/Ajpheart.00711.2001  0.514
2002 Perry GJ, Wei CC, Hankes GH, Dillon SR, Rynders P, Mukherjee R, Spinale FG, Dell'Italia LJ. Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog. Journal of the American College of Cardiology. 39: 1374-9. PMID 11955858 DOI: 10.1016/S0735-1097(02)01763-1  0.394
2002 Bradham WS, Bozkurt B, Gunasinghe H, Mann D, Spinale FG. Tumor necrosis factor-alpha and myocardial remodeling in progression of heart failure: a current perspective. Cardiovascular Research. 53: 822-30. PMID 11922892 DOI: 10.1016/S0008-6363(01)00503-X  0.512
2002 Spinale FG. Matrix metalloproteinases: regulation and dysregulation in the failing heart. Circulation Research. 90: 520-30. PMID 11909815 DOI: 10.1161/01.Res.0000013290.12884.A3  0.591
2002 Bradham WS, Moe G, Wendt KA, Scott AA, Konig A, Romanova M, Naik G, Spinale FG. TNF-alpha and myocardial matrix metalloproteinases in heart failure: relationship to LV remodeling. American Journal of Physiology. Heart and Circulatory Physiology. 282: H1288-95. PMID 11893563 DOI: 10.1152/Ajpheart.00526.2001  0.5
2002 Schultz D, Su X, Wei CC, Bishop SP, Powell P, Hankes GH, Dillon AR, Rynders P, Spinale FG, Walcott G, Ideker R, Dell'Italia LJ. Downregulation of ANG II receptor is associated with compensated pressure-overload hypertrophy in the young dog. American Journal of Physiology. Heart and Circulatory Physiology. 282: H749-56. PMID 11788426 DOI: 10.1152/Ajpheart.00228.2001  0.333
2001 Multani MM, Krombach RS, Goldberg AT, King MK, Hendrick JW, Sample JA, Baicu SC, Joffs C, DeGasparo M, Spinale FG. Myocardial bradykinin following acute angiotensin-converting enzyme inhibition, AT1 receptor blockade, or combined inhibition in congestive heart failure Journal of Cardiovascular Pharmacology and Therapeutics. 6: 369-376. PMID 11907639 DOI: 10.1177/107424840100600406  0.384
2001 Wilson EM, Spinale FG. Myocardial remodelling and matrix metalloproteinases in heart failure: turmoil within the interstitium. Annals of Medicine. 33: 623-34. PMID 11817657 DOI: 10.3109/07853890109002108  0.616
2001 Multani MM, Krombach RS, Hendrick JW, Baicu SC, Joffs C, Sample JA, deGasparo M, Spinale FG. Long-term angiotensin-converting enzyme and angiotensin I--receptor inhibition in pacing-induced heart failure: effects on myocardial interstitial bradykinin levels. Journal of Cardiac Failure. 7: 348-54. PMID 11782859 DOI: 10.1054/Jcaf.2001.29898  0.36
2001 Lucas DG, Patterson T, Hendrick JW, Holder J, Sample JA, Joffs C, Davis J, Goldberg A, Mukherjee R, Smits GJ, Spinale FG. Effects of adenosine receptor subtype A1 on ventricular and renal function. Journal of Cardiovascular Pharmacology. 38: 618-24. PMID 11588532 DOI: 10.1097/00005344-200110000-00014  0.309
2001 Etoh T, Joffs C, Deschamps AM, Davis J, Dowdy K, Hendrick J, Baicu S, Mukherjee R, Manhaini M, Spinale FG. Myocardial and interstitial matrix metalloproteinase activity after acute myocardial infarction in pigs. American Journal of Physiology. Heart and Circulatory Physiology. 281: H987-94. PMID 11514263 DOI: 10.1152/Ajpheart.2001.281.3.H987  0.808
2001 Sivasubramanian N, Coker ML, Kurrelmeyer KM, MacLellan WR, DeMayo FJ, Spinale FG, Mann DL. Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 104: 826-31. PMID 11502710 DOI: 10.1161/Hc3401.093154  0.757
2001 Coker ML, Jolly JR, Joffs C, Etoh T, Holder JR, Bond BR, Spinale FG. Matrix metalloproteinase expression and activity in isolated myocytes after neurohormonal stimulation. American Journal of Physiology. Heart and Circulatory Physiology. 281: H543-51. PMID 11454555 DOI: 10.1152/Ajpheart.2001.281.2.H543  0.833
2001 McElmurray JH, Mukherjee R, Patterson TM, Goldberg A, King MK, Hendrick JW, Gay DM, Clair MJ, Jolly JR, Spinale FG. Comparison of amlodipine or nifedipine treatment with developing congestive heart failure: Effects on myocyte contractility Journal of Cardiac Failure. 7: 158-164. PMID 11420768 DOI: 10.1054/Jcaf.2001.24374  0.314
2001 Joffs C, Gunasinghe HR, Multani MM, Dorman BH, Kratz JM, Crumbley AJ, Crawford FA, Spinale FG. Cardiopulmonary bypass induces the synthesis and release of matrix metalloproteinases. The Annals of Thoracic Surgery. 71: 1518-23. PMID 11383793 DOI: 10.1016/S0003-4975(01)02442-0  0.507
2001 Peterson JT, Hallak H, Johnson L, Li H, O'Brien PM, Sliskovic DR, Bocan TMA, Coker ML, Etoh T, Spinale FG. Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure Circulation. 103: 2303-2309. PMID 11342481 DOI: 10.1161/01.Cir.103.18.2303  0.826
2001 Ergul A, Grubbs AL, Zhang Y, Joffs C, Sample JA, King MK, Spinale FG. Expression and activity of pulmonary endothelin converting enzyme in heart failure: Relation to endothelin biosynthesis and receptor distribution Journal of Cardiac Failure. 7: 84-91. PMID 11264554 DOI: 10.1054/Jcaf.2001.22423  0.308
2001 King MK, Gay DM, Pan LC, McElmurray JH, Hendrick JW, Pirie C, Morrison A, Ding C, Mukherjee R, Spinale FG. Treatment with a growth hormone secretagogue in a model of developing heart failure: Effects on venticular and myocyte function Circulation. 103: 308-313. PMID 11208694 DOI: 10.1161/01.Cir.103.2.308  0.352
2001 Spinale FG, Lucas DG. Surgical options for the treatment of heart failure. Clinical Cornerstone. 3: 45-56. PMID 11205724 DOI: 10.1016/S1098-3597(00)90031-0  0.328
2001 Krombach RS, McElmuray JH, Gay DM, Clair MJ, Mukherjee R, Goldberg AT, Baicu SC, Spinale FG. Bradykinin degradation and relation to myocyte contractility. Journal of Cardiovascular Pharmacology and Therapeutics. 5: 291-9. PMID 11150399 DOI: 10.1054/Jcpt.2000.16694  0.311
2001 Ergul A, Grubbs AL, Zhang Y, Spinale FG. Selective upregulation of endothelin converting enzyme-1a in the human failing heart. Journal of Cardiac Failure. 6: 314-20. PMID 11145756 DOI: 10.1054/Jcaf.2000.19227  0.344
2000 Walker CA, Baicu SC, Goldberg AT, Widener CE, Fary DJ, Almany DK, Ergul A, Crawford FA, Spinale FG. Temporal endothelin dynamics of the myocardial interstitium and systemic circulation in cardiopulmonary bypass. The Journal of Thoracic and Cardiovascular Surgery. 120: 864-71. PMID 11044311 DOI: 10.1067/Mtc.2000.109700  0.316
2000 Spinale FG, Coker ML, Heung LJ, Bond BR, Gunasinghe HR, Etoh T, Goldberg AT, Zellner JL, Crumbley AJ. A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure. Circulation. 102: 1944-9. PMID 11034943 DOI: 10.1161/01.Cir.102.16.1944  0.832
2000 New RB, Sampson AC, King MK, Hendrick JW, Clair MJ, McElmurray JH, Mandel J, Mukherjee R, De Gasparo M, Spinale FG. Effects of combined angiotensin II and endothelin receptor blockade with developing heart failure: Effects on left ventricular performance Circulation. 102: 1447-1453. PMID 10993866 DOI: 10.1161/01.Cir.102.12.1447  0.349
2000 Spinale FG. Novel approaches to retard ventricular remodeling in heart failure. European Journal of Heart Failure. 1: 17-23. PMID 10937974 DOI: 10.1016/S1388-9842(98)00012-9  0.597
2000 Ergul A, Walker CA, Goldberg A, Baicu SC, Hendrick JW, King MK, Spinale FG. ET-1 in the myocardial interstitium: relation to myocyte ECE activity and expression. American Journal of Physiology. Heart and Circulatory Physiology. 278: H2050-6. PMID 10843904 DOI: 10.1152/Ajpheart.2000.278.6.H2050  0.369
2000 Dorman BH, New RB, Bond BR, Mukherjee R, Mukhin YV, McElmurray JH, Spinale FG. Myocyte endothelin exposure during cardioplegic arrest exacerbates contractile dysfunction after reperfusion. Anesthesia and Analgesia. 90: 1080-5. PMID 10781456 DOI: 10.1097/00000539-200005000-00014  0.333
2000 Spinale FG, Coker ML, Bond BR, Zellner JL. Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target. Cardiovascular Research. 46: 225-38. PMID 10773226 DOI: 10.1016/S0008-6363(99)00431-9  0.846
2000 Goldberg AT, Bond BR, Mukherjee R, New RB, Zellner JL, Crawford FA, Spinale FG. Endothelin receptor pathway in human left ventricular myocytes: relation to contractility. The Annals of Thoracic Surgery. 69: 711-5; discussion 71. PMID 10750748 DOI: 10.1016/S0003-4975(99)01515-5  0.374
2000 Dorman BH, Sade RM, Burnette JS, Wiles HB, Pinosky ML, Reeves ST, Bond BR, Spinale FG. Magnesium supplementation in the prevention of arrhythmias in pediatric patients undergoing surgery for congenital heart defects. American Heart Journal. 139: 522-8. PMID 10689268 DOI: 10.1016/S0002-8703(00)90097-8  0.309
2000 Nagatsu M, Spinale FG, Koide M, Tagawa H, DeFreitas G, Cooper G, Carabello BA. Bradycardia and the role of beta-blockade in the amelioration of left ventricular dysfunction. Circulation. 101: 653-9. PMID 10673258 DOI: 10.1161/01.Cir.101.6.653  0.323
2000 Roten L, Nemoto S, Simsic J, Coker ML, Rao V, Baicu S, Defreyte G, Soloway PJ, Zile MR, Spinale FG. Effects of gene deletion of the tissue inhibitor of the matrix metalloproteinase-type 1 (TIMP-1) on left ventricular geometry and function in mice. Journal of Molecular and Cellular Cardiology. 32: 109-20. PMID 10652195 DOI: 10.1006/Jmcc.1999.1052  0.814
2000 Walker CA, Crawford FA, Spinale FG. Myocyte contractile dysfunction with hypertrophy and failure: relevance to cardiac surgery. The Journal of Thoracic and Cardiovascular Surgery. 119: 388-400. PMID 10649220 DOI: 10.1016/S0022-5223(00)70199-1  0.335
2000 Nagatomo Y, Carabello BA, Coker ML, McDermott PJ, Nemoto S, Hamawaki M, Spinale FG. Differential effects of pressure or volume overload on myocardial MMP levels and inhibitory control. American Journal of Physiology. Heart and Circulatory Physiology. 278: H151-61. PMID 10644594 DOI: 10.1152/Ajpheart.2000.278.1.H151  0.834
1999 Coker ML, Doscher MA, Thomas CV, Galis ZS, Spinale FG. Matrix metalloproteinase synthesis and expression in isolated LV myocyte preparations. American Journal of Physiology. Heart and Circulatory Physiology. 277: H777-H787. PMID 29592371 DOI: 10.1152/ajpheart.1999.277.2.H777  0.82
1999 Balaji S, Hewett KW, Krombach RS, Clair MJ, Ye X, Spinale FG. Inducible lethal ventricular arrhythmias in swine with pacing-induced heart failure. Basic Research in Cardiology. 94: 496-503. PMID 10651162 DOI: 10.1007/S003950050166  0.35
1999 Spinale FG. Cellular and molecular therapeutic targets for treatment of contractile dysfunction after cardioplegic arrest. The Annals of Thoracic Surgery. 68: 1934-41. PMID 10585107 DOI: 10.1016/S0003-4975(99)01034-6  0.38
1999 Loging JA, New RB, Baicu SC, King MK, Hendrick JW, Crawford FA, de Gasparo M, Spinale FG. Effects of angiotensin type-I receptor blockade on pericardial fibrosis. The Journal of Surgical Research. 87: 101-7. PMID 10527710 DOI: 10.1006/Jsre.1999.5732  0.307
1999 Krombach RS, Clair MJ, Hendrick JW, Mukherjee R, Houck WV, Hebbar L, Kribbs SB, Dodd MG, Spinale FG. Amlodipine therapy in congestive heart failure: hemodynamic and neurohormonal effects at rest and after treadmill exercise. The American Journal of Cardiology. 84: 3L-15L. PMID 10480440 DOI: 10.1016/S0002-9149(99)00359-8  0.354
1999 Spinale FG, Coker ML, Krombach SR, Mukherjee R, Hallak H, Houck WV, Clair MJ, Kribbs SB, Johnson LL, Peterson JT, Zile MR. Matrix metalloproteinase inhibition during the development of congestive heart failure: Effects on left ventricular dimensions and function Circulation Research. 85: 364-376. PMID 10455065 DOI: 10.1161/01.Res.85.4.364  0.814
1999 Coker ML, Doscher MA, Thomas CV, Galis ZS, Spinale FG. Matrix metalloproteinase synthesis and expression in isolated LV myocyte preparations. The American Journal of Physiology. 277: H777-87. PMID 10444506 DOI: 10.1016/S1071-9164(98)90057-4  0.831
1999 Rao VU, Spinale FG. Controlling myocardial matrix remodeling: implications for heart failure. Cardiology in Review. 7: 136-43. PMID 10423664 DOI: 10.1097/00045415-199905000-00010  0.592
1999 Coker ML, Zellner JL, Crumbley AJ, Spinale FG. Defects in matrix metalloproteinase inhibitory stoichiometry and selective MMP induction in patients with nonischemic or ischemic dilated cardiomyopathy. Annals of the New York Academy of Sciences. 878: 559-62. PMID 10415772 DOI: 10.1111/J.1749-6632.1999.Tb07726.X  0.808
1999 Spinale FG, Iannini JP, Mukherjee R, Melton DM, de Gasparo M. Angiotensin AT1 receptor inhibition, angiotensin-converting enzyme inhibition, and combination therapy with developing heart failure: cellular mechanisms of action. Journal of Cardiac Failure. 4: 325-32. PMID 9924854 DOI: 10.1016/S1071-9164(98)90238-X  0.373
1999 Mukherjee R, Spinale FG. Heart Failure Reviews. 4: 319-327. DOI: 10.1023/A:1009899502335  0.388
1999 Bond BR, Coker ML, Heung LJ, Zellner JL, Spinale FG. Identification of novel matrix metalloproteinase inducers and activators in normal adult human left ventricular myocytes Journal of Cardiac Failure. 5: 15. DOI: 10.1016/S1071-9164(99)91397-0  0.798
1999 Coker ML, Heung LJ, Morrison AE, Zellner JL, Crumbley AJ, Spinale FG. A novel MMP stimulatory protein, EMMPRIN, is expressed in human myocardium and is upregulated in dilated cardiomyopathy Journal of Cardiac Failure. 5: 15. DOI: 10.1016/S1071-9164(99)91396-9  0.794
1998 Coker ML, Thomas CV, Clair MJ, Hendrick JW, Krombach RS, Galis ZS, Spinale FG. Myocardial matrix metalloproteinase activity and abundance with congestive heart failure. American Journal of Physiology. Heart and Circulatory Physiology. 274: H1516-H1523. PMID 29586519 DOI: 10.1152/ajpheart.1998.274.5.H1516  0.833
1998 Coker ML, Spinale FG. Myocardial extracellular matrix remodeling with the development of pacing induced congestive heart failure contributory mechanisms. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 7: 161-8. PMID 25851223 DOI: 10.1016/S1054-8807(97)00120-8  0.843
1998 Clair MJ, Krombach RS, Coker ML, Heslin TL, Kribbs SB, de Gasparo M, Spinale FG. Angiotensin AT1 receptor inhibition in pacing induced heart failure: effects on left ventricular myocardial collagen content and composition. Journal of Molecular and Cellular Cardiology. 30: 2355-64. PMID 9925371 DOI: 10.1006/Jmcc.1998.0796  0.796
1998 Saad D, Mukherjee R, Thomas PB, Iannini JP, Basler CG, Hebbar L, O SJ, Moreland S, Webb ML, Powell JR, Spinale FG. The effects of endothelin-A receptor blockade during the progression of pacing-induced congestive heart failure. Journal of the American College of Cardiology. 32: 1779-86. PMID 9822109 DOI: 10.1016/S0735-1097(98)00439-2  0.355
1998 Mann DL, Spinale FG. Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds. Circulation. 98: 1699-702. PMID 9788821 DOI: 10.1161/01.Cir.98.17.1699  0.511
1998 Spinale FG, Mukherjee R, Krombach RS, Clair MJ, Hendrick JW, Houck WV, Hebbar L, Kribbs SB, Zellner JL, Dodd MG. Chronic amlodipine treatment during the development of heart failure. Circulation. 98: 1666-74. PMID 9778333 DOI: 10.1161/01.Cir.98.16.1666  0.364
1998 Krombach RS, Clair MJ, Hendrick JW, Houck WV, Zellner JL, Kribbs SB, Whitebread S, Mukherjee R, de Gasparo M, Spinale FG. Angiotensin converting enzyme inhibition, AT1 receptor inhibition, and combination therapy with pacing induced heart failure: effects on left ventricular performance and regional blood flow patterns. Cardiovascular Research. 38: 631-45. PMID 9747431 DOI: 10.1016/S0008-6363(98)00050-9  0.353
1998 New RB, Zellner JL, Hebbar L, Mukherjee R, Sampson AC, Hendrick JW, Handy JR, Crawford FA, Spinale FG. Isolated left ventricular myocyte contractility in patients undergoing cardiac operations. The Journal of Thoracic and Cardiovascular Surgery. 116: 495-502. PMID 9731792 DOI: 10.1016/S0022-5223(98)70016-9  0.392
1998 Mukherjee R, Hewett KW, Walker JD, Basler CG, Spinale FG. Changes in L-type calcium channel abundance and function during the transition to pacing-induced congestive heart failure. Cardiovascular Research. 37: 432-44. PMID 9614498 DOI: 10.1016/S0008-6363(97)00128-4  0.354
1998 Coker ML, Thomas CV, Clair MJ, Hendrick JW, Krombach RS, Galis ZS, Spinale FG. Myocardial matrix metalloproteinase activity and abundance with congestive heart failure. The American Journal of Physiology. 274: H1516-23. PMID 9612358 DOI: 10.1152/Ajpheart.1998.274.5.H1516  0.844
1998 Houck WV, Kribbs SB, Zellner JL, Doscher MA, Joshi JD, Crawford FA, Spinale FG. Normothermic versus hypothermic hyperkalemic cardioplegia: effects on myocyte contractility. The Annals of Thoracic Surgery. 65: 1279-83. PMID 9594851 DOI: 10.1016/S0003-4975(98)00174-X  0.335
1998 Thomas CV, Coker ML, Zellner JL, Handy JR, Crumbley AJ, Spinale FG. Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy. Circulation. 97: 1708-15. PMID 9591765 DOI: 10.1161/01.Cir.97.17.1708  0.831
1998 Bozkurt B, Kribbs SB, Clubb FJ, Michael LH, Didenko VV, Hornsby PJ, Seta Y, Oral H, Spinale FG, Mann DL. Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats. Circulation. 97: 1382-91. PMID 9577950 DOI: 10.1161/01.Cir.97.14.1382  0.304
1998 Hebbar L, Houck WV, Zellner JL, Dorman BH, Spinale FG. Temporal relation of ATP-sensitive potassium-channel activation and contractility before cardioplegia. The Annals of Thoracic Surgery. 65: 1077-82. PMID 9564931 DOI: 10.1016/S0003-4975(98)00092-7  0.335
1998 Eble DM, Walker JD, Samarel AM, Spinale FG. Myosin heavy chain synthesis during the progression of chronic tachycardia induced heart failure in rabbits. Basic Research in Cardiology. 93: 50-5. PMID 9538937 DOI: 10.1007/S003950050061  0.417
1998 Spinale FG, Coker ML, Thomas CV, Walker JD, Mukherjee R, Hebbar L. Time-dependent changes in matrix metalloproteinase activity and expression during the progression of congestive heart failure: relation to ventricular and myocyte function. Circulation Research. 82: 482-95. PMID 9506709 DOI: 10.1161/01.Res.82.4.482  0.846
1998 Hedgepath KR, Mukherjee R, Wang Z, Spinale FG. The relation between changes in myocyte orientation and contractile function with electrical field stimulation. Basic Research in Cardiology. 92: 385-90. PMID 9464862 DOI: 10.1007/Bf00796212  0.304
1998 Spinale FG, Holzgrefe HH, Walker JD, Mukherjee R, Kribbs SB, Powell JR, Antonaccio M. Angiotensin II subtype-1 receptor blockade during the development of left ventricular hypertrophy in dogs: effects on ventricular and myocyte function. Journal of Cardiovascular Pharmacology. 30: 623-31. PMID 9388045 DOI: 10.1097/00005344-199711000-00013  0.381
1998 Clair MJ, Krombach R, Hendrick JW, Kribbs SB, Mukherjee R, Spinale FG. Chronic amlodipine treatment improves left ventricular function, systemic hemodynamics and neurohormonal status with congestive heart failure Journal of Cardiac Failure. 4: 46. DOI: 10.1016/S1071-9164(98)90169-5  0.363
1997 Spinale FG, Mukherjee R, Iannini JP, Whitebread S, Hebbar L, Clair MJ, Melton DM, Cox MH, Thomas PB, de Gasparo M. Modulation of the renin-angiotensin pathway through enzyme inhibition and specific receptor blockade in pacing-induced heart failure: II. Effects on myocyte contractile processes. Circulation. 96: 2397-406. PMID 9337216 DOI: 10.1161/01.Cir.96.7.2397  0.333
1997 Spinale FG, de Gasparo M, Whitebread S, Hebbar L, Clair MJ, Melton DM, Krombach RS, Mukherjee R, Iannini JP, O SJ. Modulation of the renin-angiotensin pathway through enzyme inhibition and specific receptor blockade in pacing-induced heart failure: I. Effects on left ventricular performance and neurohormonal systems. Circulation. 96: 2385-96. PMID 9337215 DOI: 10.1161/01.Cir.96.7.2385  0.365
1997 Dorman BH, Hebbar L, Hinton RB, Roy RC, Spinale FG. Preservation of myocyte contractile function after hyperthermic cardioplegic arrest by activation of ATP-sensitive potassium channels. Circulation. 96: 2376-84. PMID 9337214 DOI: 10.1161/01.Cir.96.7.2376  0.33
1997 Walker JD, Kratz JM, Basler CG, Meck LP, Stratton JR, Kribbs SB, Crawford FA, Spinale FG. Fate of gelatin-resorcinol-formaldehyde/glutaraldeyde adhesive on femoral vessel morphology. The Journal of Surgical Research. 71: 73-8. PMID 9271281 DOI: 10.1006/Jsre.1997.5128  0.325
1997 Wang Z, Lam CF, Mukherjee R, Hebbar L, Wang Y, Spinale FG. Relationship between external load and isolated myocyte contractile function with CHF in pigs. The American Journal of Physiology. 273: H183-91. PMID 9249489 DOI: 10.1152/Ajpheart.1997.273.1.H183  0.334
1997 Hinton RB, Hebbar L, Cox MH, Mukherjee R, Joshi JD, Crawford FA, Spinale FG. Left ventricular regional myocyte contractility in normal and heart failure states. Journal of Molecular and Cellular Cardiology. 29: 1939-46. PMID 9236147 DOI: 10.1006/Jmcc.1997.0434  0.372
1997 Melton DM, Holzgrefe HH, Walker JD, Mukherjee R, Arthur SR, Antonaccio MJ, Koster WH, Spinale FG. Effects of chronic angiotensin-converting enzyme inhibition on left ventricular and myocyte structure and function during recovery from chronic rapid pacing. Journal of Molecular and Cellular Cardiology. 29: 697-710. PMID 9140827 DOI: 10.1006/Jmcc.1996.0312  0.355
1997 Cox MH, O SJ, Hebbar L, Mukherjee R, Crawford FA, Spinale FG. Protective effects of adenosine on myocyte contractility during cardioplegic arrest. The Annals of Thoracic Surgery. 63: 981-7. PMID 9124975 DOI: 10.1016/S0003-4975(96)01252-0  0.365
1997 Eble DM, Walker JD, Mukherjee R, Samarel AM, Spinale FG. Myosin heavy chain synthesis is increased in a rabbit model of heart failure. The American Journal of Physiology. 272: H969-78. PMID 9124461 DOI: 10.1152/Ajpheart.1997.272.2.H969  0.382
1997 Spinale FG, Walker JD, Mukherjee R, Iannini JP, Keever AT, Gallagher KP. Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits. Beneficial effects on left ventricular and myocyte function. Circulation. 95: 1918-29. PMID 9107181 DOI: 10.1161/01.Cir.95.7.1918  0.402
1997 Hebbar L, Dorman BH, Clair MJ, Roy RC, Spinale FG. Negative and selective effects of propofol on isolated swine myocyte contractile function in pacing-induced congestive heart failure. Anesthesiology. 86: 649-59. PMID 9066332 DOI: 10.1097/00000542-199703000-00018  0.386
1997 Thomas PB, Liu EC, Webb ML, Mukherjee R, Hebbar L, Spinale FG. Exogenous effects and endogenous production of endothelin in cardiac myocytes: potential significance in heart failure. The American Journal of Physiology. 271: H2629-37. PMID 8997325 DOI: 10.1152/Ajpheart.1996.271.6.H2629  0.322
1996 Spinale FG, Johnson WS, Wang Y, Wang Z, Mukherjee R, Hebbar L, Jones BU. Direct effects of chronic beta-adrenergic receptor blockade on left ventricular and myocyte function in a model of tachycardia-induced congestive heart failure. Journal of Cardiac Failure. 2: 311-8. PMID 8989646 DOI: 10.1016/S1071-9164(96)80018-2  0.352
1996 Spinale FG, Zellner JL, Johnson WS, Eble DM, Munyer PD. Cellular and extracellular remodeling with the development and recovery from tachycardia-induced cardiomyopathy: changes in fibrillar collagen, myocyte adhesion capacity and proteoglycans. Journal of Molecular and Cellular Cardiology. 28: 1591-608. PMID 8877770 DOI: 10.1006/Jmcc.1996.0150  0.461
1996 McMahon WS, Holzgrefe HH, Walker JD, Mukherjee R, Arthur SR, Cavallo MJ, Child MJ, Spinale FG. Cellular basis for improved left ventricular pump function after digoxin therapy in experimental left ventricular failure. Journal of the American College of Cardiology. 28: 495-505. PMID 8800131 DOI: 10.1016/0735-1097(96)00151-9  0.398
1996 Reed CE, Dorman BH, Spinale FG. Mechanisms of right ventricular dysfunction after pulmonary resection. The Annals of Thoracic Surgery. 62: 225-31; discussion 2. PMID 8678647 DOI: 10.1016/0003-4975(96)00258-5  0.327
1996 McMahon WS, Gillette PC, Hinton RB, Stratton JR, Crawford FA, Spinale FG. Developmental differences in myocyte contractile response after cardioplegic arrest. The Journal of Thoracic and Cardiovascular Surgery. 111: 1257-66. PMID 8642828 DOI: 10.1016/S0022-5223(96)70229-5  0.326
1996 Dorman BH, Cavallo MJ, Hinton RB, Roy RC, Spinale FG. Preservation of myocyte contractile function after hypothermic, hyperkalemic cardioplegic arrest with 2, 3-butanedione monoxime. The Journal of Thoracic and Cardiovascular Surgery. 111: 621-9. PMID 8601977 DOI: 10.1016/S0022-5223(96)70314-8  0.303
1996 Zellner JL, Hebbar L, Crawford FA, Mukherjee R, Spinale FG. Beneficial effects of myocyte preconditioning on contractile processes after cardioplegic arrest. The Annals of Thoracic Surgery. 61: 558-64. PMID 8572767 DOI: 10.1016/0003-4975(95)01092-0  0.359
1996 Mukherjee R, Hewett KW, Spinale FG. Myocyte electrophysiological properties following the development of supraventricular tachycardia-induced cardiomyopathy. Journal of Molecular and Cellular Cardiology. 27: 1333-48. PMID 8531216 DOI: 10.1016/S0022-2828(05)82396-X  0.307
1996 Seung-Jun O, Cox MH, Mukherjee R, Clair MJ, Crawford FA, Spinale FG. The direct effects of protamine sulfate on myocyte contractile function following hypothermic hyperkalemic cardioplegic arrest Journal of the American College of Cardiology. 27: 233. DOI: 10.1016/S0735-1097(96)81804-3  0.308
1996 Spinale FG, Johnson WS, Wang Y, Wang Z, Mukherjee R, Hebbar L. Direct effects of chronic β-adrenergic receptor blockade on LV and myocyte function in tachycardia induced congestive heart failure (CHF) Journal of the American College of Cardiology. 27: 113-114. DOI: 10.1016/S0735-1097(96)80671-1  0.335
1996 Thomas PB, Liu EC, Webb ML, Mukherjee R, Spinale FG. Evidence of an endothelin-1 autocrine loop in cardiac myocytes: Relation to contractile function with congestive heart failure Journal of the American College of Cardiology. 27: 56. DOI: 10.1016/S0735-1097(96)80416-5  0.372
1996 McMahon WS, Mukherjee R, Gillette PC, Crawford FA, Spinale FG. Right and left ventricular geometry and myocyte contractile processes with dilated cardiomyopathy: myocyte growth and  -adrenergic responsiveness Cardiovascular Research. 31: 314-323. DOI: 10.1016/S0008-6363(95)00212-X  0.392
1996 O S, Cox MH, Mukherjee R, Clair MJ, Crawford FA, Spinale FG. Direct and interactive effects of cardioplegic arrest and protamine on myocyte contractility The Annals of Thoracic Surgery. 62: 489-494. DOI: 10.1016/0003-4975(96)00314-1  0.34
1995 Spinale FG, Holzgrefe HH, Mukherjee R, Arthur SR, Child MJ, Powell JR, Koster WH. LV and myocyte structure and function after early recovery from tachycardia-induced cardiomyopathy. The American Journal of Physiology. 268: H836-47. PMID 7864211 DOI: 10.1152/Ajpheart.1995.268.2.H836  0.386
1995 Hird RB, Crawford FA, Spinale FG. Differential effects of protamine sulfate on myocyte contractile function with left ventricular failure. Journal of the American College of Cardiology. 25: 773-80. PMID 7860928 DOI: 10.1016/0735-1097(94)00429-T  0.388
1995 Hird RB, Crawford FA, Mukherjee R, Spinale FG. Direct effects of thrombin on myocyte contractile function. The Annals of Thoracic Surgery. 59: 288-93. PMID 7847939 DOI: 10.1016/0003-4975(94)00975-D  0.348
1995 Zile MR, Mukherjee R, Clayton C, Kato S, Spinale FG. Effects of chronic supraventricular pacing tachycardia on relaxation rate in isolated cardiac muscle cells. The American Journal of Physiology. 268: H2104-13. PMID 7771561 DOI: 10.1152/Ajpheart.1995.268.5.H2104  0.348
1995 Cavallo MJ, Dorman BH, Spinale FG, Roy RC. Myocyte contractile responsiveness after hypothermic, hyperkalemic cardioplegic arrest: Disparity between exogenous calcium and β-adrenergic stimulation Anesthesiology. 82: 926-939. PMID 7717565 DOI: 10.1097/00000542-199504000-00016  0.332
1995 Walker JD, Crawford FA, Spinale FG. 3,5,3' Triiodo-L-thyronine pretreatment with cardioplegic arrest and chronic left ventricular dysfunction. The Annals of Thoracic Surgery. 60: 292-9. PMID 7646089 DOI: 10.1016/0003-4975(95)00368-U  0.362
1995 Walker JD, Crawford FA, Spinale FG. Pretreatment with 3,5,3'triiodo-L-thyronine (T3). Effects on myocyte contractile function after hypothermic cardioplegic arrest and rewarming. The Journal of Thoracic and Cardiovascular Surgery. 110: 315-27. PMID 7637349 DOI: 10.1016/S0022-5223(95)70227-X  0.356
1995 Spinale FG, Holzgrefe HH, Mukherjee R, Hird RB, Walker JD, Arnim-Barker A, Powell JR, Koster WH. Angiotensin-converting enzyme inhibition and the progression of congestive cardiomyopathy. Effects on left ventricular and myocyte structure and function. Circulation. 92: 562-78. PMID 7634471 DOI: 10.1161/01.Cir.92.3.562  0.408
1995 Hird RB, Wakefield TW, Mukherjee R, Jones BU, Crawford FA, Andrews PC, Stanley JC, Spinale FG. Direct effects of protamine sulfate on myocyte contractile processes. Cellular and molecular mechanisms. Circulation. 92: II433-46. PMID 7586451 DOI: 10.1161/01.Cir.92.9.433  0.36
1995 Kato S, Spinale FG, Tanaka R, Johnson W, Cooper G, Zile MR. Inhibition of collagen cross-linking: effects on fibrillar collagen and ventricular diastolic function. The American Journal of Physiology. 269: H863-8. PMID 7573529 DOI: 10.1152/Ajpheart.1995.269.3.H863  0.397
1994 Hird RB, Crawford FA, Mukherjee R, Zile MR, Spinale FG. Effects of protamine on myocyte contractile function and beta-adrenergic responsiveness. The Annals of Thoracic Surgery. 57: 1066-74; discussion . PMID 8179366 DOI: 10.1016/0003-4975(94)91331-5  0.301
1994 Tsutsui H, Spinale FG, Nagatsu M, Schmid PG, Ishihara K, DeFreyte G, Cooper IV G, Carabello BA. Effects of chronic β-adrenergic blockade on the left ventricular and cardiocyte abnormalities of chronic canine mitral regurgitation Journal of Clinical Investigation. 93: 2639-2648. PMID 7911128 DOI: 10.1172/Jci117277  0.316
1994 Spinale FG, Eble DM, Mukherjee R, Johnson WS, Walker JD. Left ventricular and myocyte structure and function following chronic ventricular tachycardia in rabbits. Basic Research in Cardiology. 89: 456-67. PMID 7702537 DOI: 10.1007/Bf00788282  0.387
1994 Hird RB, Spinale FG, Hewett KW, Mukherjee R, Crawford FA. The direct effects of protamine sulfate on myocyte contractile processes The Journal of Thoracic and Cardiovascular Surgery. 108: 1100-1114. DOI: 10.1016/S0022-5223(94)70153-9  0.33
1993 Urabe Y, Hamada Y, Spinale FG, Carabello BA, Kent RL, Cooper G, Mann DL. Cardiocyte contractile performance in experimental biventricular volume-overload hypertrophy. The American Journal of Physiology. 264: H1615-23. PMID 8498574 DOI: 10.1152/Ajpheart.1993.264.5.H1615  0.377
1993 Cheng W, Michele JJ, Spinale FG, Sink JD, Santamore WP. Effects of cardiomyoplasty on biventricular function in canine chronic heart failure. The Annals of Thoracic Surgery. 55: 893-901. PMID 8466345 DOI: 10.1016/0003-4975(93)90113-V  0.376
1993 Zile MR, Tomita M, Ishihara K, Nakano K, Lindroth J, Spinale F, Swindle M, Carabello BA. Changes in diastolic function during development and correction of chronic LV volume overload produced by mitral regurgitation. Circulation. 87: 1378-88. PMID 8462159 DOI: 10.1161/01.Cir.87.4.1378  0.385
1993 Spinale FG, Ishihra K, Zile M, DeFryte G, Crawford FA, Carabello BA. Structural basis for changes in left ventricular function and geometry because of chronic mitral regurgitation and after correction of volume overload The Journal of Thoracic and Cardiovascular Surgery. 106: 1147-1157. DOI: 10.1016/S0022-5223(19)33992-3  0.388
1992 Spinale FG, Tanaka R, Crawford FA, Zile MR. Changes in myocardial blood flow during development of and recovery from tachycardia-induced cardiomyopathy. Circulation. 85: 717-29. PMID 1735164 DOI: 10.1161/01.Cir.85.2.717  0.395
1992 Spinale FG, Fulbright BM, Mukherjee R, Tanaka R, Hu J, Crawford FA, Zile MR. Relation between ventricular and myocyte function with tachycardia-induced cardiomyopathy. Circulation Research. 71: 174-87. PMID 1606661 DOI: 10.1161/01.Res.71.1.174  0.362
1992 Spinale FG, Grine RC, Tempel GE, Crawford FA, Zile MR. Alterations in the myocardial capillary vasculature accompany tachycardia-induced cardiomyopathy. Basic Research in Cardiology. 87: 65-79. PMID 1567354 DOI: 10.1007/Bf00795391  0.371
1992 Spinale FG, Mukherjee R, Tanaka R, Zile MR. The effects of valvular regurgitation on thermodilution ejection fraction measurements. Chest. 101: 723-31. PMID 1541138 DOI: 10.1378/Chest.101.3.723  0.344
1992 Tanaka R, Spinale FG, Crawford FA, Zile MR. Effect of chronic supraventricular tachycardia on left ventricular function and structure in newborn pigs. Journal of the American College of Cardiology. 20: 1650-60. PMID 1452940 DOI: 10.1016/0735-1097(92)90462-V  0.383
1992 Zile MR, Tanaka R, Lindroth JR, Spinale F, Carabello BA, Mirsky I. Left ventricular volume determined echocardiographically by assuming a constant left ventricular epicardial long-axis/short-axis dimension ratio throughout the cardiac cycle. Journal of the American College of Cardiology. 20: 986-993. PMID 1388183 DOI: 10.1016/0735-1097(92)90202-X  0.398
1992 Spinale FG, Clayton C, Tanaka R, Fulbright BM, Mukherjee R, Schulte BA, Crawford FA, Zile MR. Myocardial Na+,K(+)-ATPase in tachycardia induced cardiomyopathy. Journal of Molecular and Cellular Cardiology. 24: 277-94. PMID 1320703 DOI: 10.1016/0022-2828(92)93165-G  0.33
1992 Burchell SA, Spinale FG, Crawford FA, Tanaka R, Zile MR. Effects of chronic tachycardia-induced cardiomyopathy on the β-adrenergic receptor system The Journal of Thoracic and Cardiovascular Surgery. 104: 1006-1012. DOI: 10.1016/S0022-5223(19)34685-9  0.346
1991 Smith AC, Spinale FG, Carabello BA, Swindle MM. Technical aspects of cardiac catheterization of swine. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 2: 187-94. PMID 2487247 DOI: 10.3109/08941938909015350  0.313
1991 Spinale FG, Zellner JL, Mukherjee R, Crawford FA. Placement considerations for measuring thermodilution right ventricular ejection fractions. Critical Care Medicine. 19: 417-421. PMID 1999105 DOI: 10.1097/00003246-199103000-00023  0.32
1991 Tomita M, Spinale FG, Crawford FA, Zile MR. Changes in left ventricular volume, mass, and function during the development and regression of supraventricular tachycardia-induced cardiomyopathy. Disparity between recovery of systolic versus diastolic function. Circulation. 83: 635-44. PMID 1991381 DOI: 10.1161/01.Cir.83.2.635  0.388
1991 Zellner JL, Spinale FG, Crawford FA, Cook JA. Right ventricular pump dysfunction with acute experimental septic shock. The Journal of Surgical Research. 50: 93-9. PMID 1987437 DOI: 10.1016/0022-4804(91)90016-F  0.333
1991 Spinale FG, Zellner JL, Tomita M, Crawford FA, Zile MR. Relation between ventricular and myocyte remodeling with the development and regression of supraventricular tachycardia-induced cardiomyopathy. Circulation Research. 69: 1058-67. PMID 1934334 DOI: 10.1161/01.Res.69.4.1058  0.348
1991 Trippel DL, Harold ME, Spinale FG, Buckles DS, Gillette PC. The acute effects of flecainide in the swine heart failing from incessant supraventricular tachycardia. American Heart Journal. 121: 1721-6. PMID 1903580 DOI: 10.1016/0002-8703(91)90018-D  0.414
1991 Spinale FG, Tomita M, Zellner JL, Cook JC, Crawford FA, Zile MR. Collagen remodeling and changes in LV function during development and recovery from supraventricular tachycardia. The American Journal of Physiology. 261: H308-18. PMID 1877659 DOI: 10.1152/Ajpheart.1991.261.2.H308  0.415
1991 Zellner JL, Spinale FG, Eble DM, Hewett KW, Crawford FA. Alterations in myocyte shape and basement membrane attachment with tachycardia-induced heart failure. Circulation Research. 69: 590-600. PMID 1873861 DOI: 10.1161/01.Res.69.3.590  0.43
1991 Spinale FG, Zellner JL, Tomita M, Tempel GE, Crawford FA, Zile MR. Tachycardia-induced cardiomyopathy: effects on blood flow and capillary structure. The American Journal of Physiology. 261: H140-8. PMID 1858914 DOI: 10.1152/Ajpheart.1991.261.1.H140  0.382
1991 Swindle MM, Spinale FG, Smith AC, Schumann RE, Green CT, Nakano K, Kanasawa S, Ishihara K, Zile MR, Carabello BA. Anesthetic and postoperative protocols for a canine model of reversible left ventricular volume overload. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 4: 339-46. PMID 1832953 DOI: 10.3109/08941939109141166  0.379
1991 Nakano K, Swindle MM, Spinale F, Ishihara K, Kanazawa S, Smith A, Biederman RW, Clamp L, Hamada Y, Zile MR. Depressed contractile function due to canine mitral regurgitation improves after correction of the volume overload. Journal of Clinical Investigation. 87: 2077-2086. PMID 1828252 DOI: 10.1172/Jci115238  0.335
1991 Spinale FG, Crawford FA, Hewett KW, Carabello BA. Ventricular failure and cellular remodeling with chronic supraventricular tachycardia The Journal of Thoracic and Cardiovascular Surgery. 102: 874-882. DOI: 10.1016/S0022-5223(19)33937-6  0.375
1990 Spinale FG, Hendrick DA, Crawford FA, Smith AC, Hamada Y, Carabello BA. Chronic supraventricular tachycardia causes ventricular dysfunction and subendocardial injury in swine. The American Journal of Physiology. 259: H218-29. PMID 2375409 DOI: 10.1152/Ajpheart.1990.259.1.H218  0.388
1990 Spinale FG, Hendrick DA, Crawford FA, Carabello BA. Relationship between bioimpedance, thermodilution, and ventriculographic measurements in experimental congestive heart failure. Cardiovascular Research. 24: 423-9. PMID 2372797 DOI: 10.1093/Cvr/24.5.423  0.368
1990 Spinale FG, Carabello BA, Crawford FA. Right ventricular function and three-dimensional modeling using computer-aided design. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 1707-16. PMID 2347808 DOI: 10.1152/Jappl.1990.68.4.1707  0.309
1990 Spinale FG, Smith AC, Crawford FA. Relationship of bioimpedance to thermodilution and echocardiographic measurements of cardiac function. Critical Care Medicine. 18: 414-8. PMID 2318052 DOI: 10.1097/00003246-199004000-00013  0.368
1990 Spinale FG, Carabello BA, Schulte BA, Crawford FA. Wavefront myocyte injury and relationship to function in right ventricular ischemia. The American Journal of Physiology. 258: H292-304. PMID 2309899 DOI: 10.1152/Ajpheart.1990.258.2.H292  0.343
1990 Spinale FG, Zellner JL, Mukherjee R, Ferris SE, Crawford FA. Thermodilution right ventricular ejection fraction. Catheter positioning effects. Chest. 98: 1259-65. PMID 2225977 DOI: 10.1378/Chest.98.5.1259  0.341
1990 Spinale FG, Smith AC, Carabello BA, Crawford FA. Right ventricular function computed by thermodilution and ventriculography The Journal of Thoracic and Cardiovascular Surgery. 99: 141-152. DOI: 10.1016/S0022-5223(19)35644-2  0.36
1990 Tomita M, Spinale FG, Crawford FA, Smith A, Zile MR. Abstract of papers to be presented at the 39th Annual Scientific Session of the American College of Cardiology, New Orleans, Louisiana, March 18–22, 1990Changes in left ventricular volume, mass and function during development and regression of supraventricular tachycardia induced cardiomyopathy: Disparity between recovery of systolic vs diastolic function Journal of the American College of Cardiology. 15. DOI: 10.1016/0735-1097(90)92694-W  0.335
1989 Leman RB, Spinale FG, Dorn GW, Cooper G, Spann JF, Gillette PC, Carabello BA. Supernormal ejection performance is isolated to the ipsilateral congenitally pressure-overloaded ventricle. Journal of the American College of Cardiology. 13: 1314-9. PMID 2522958 DOI: 10.1016/0735-1097(89)90307-0  0.354
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