Judy L. Meinkoth - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Pharmacology, Cell Biology, General Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Tsygankova OM, Wang H, Meinkoth JL. Tumor cell migration and invasion are enhanced by depletion of Rap1 GTPase-activating protein (Rap1GAP). The Journal of Biological Chemistry. 288: 24636-46. PMID 23864657 DOI: 10.1074/Jbc.M113.464594  0.532
2012 Dong X, Tang W, Stopenski S, Brose MS, Korch C, Meinkoth JL. RAP1GAP inhibits cytoskeletal remodeling and motility in thyroid cancer cells. Endocrine-Related Cancer. 19: 575-88. PMID 22696507 DOI: 10.1530/Erc-12-0086  0.579
2011 Vuchak LA, Tsygankova OM, Meinkoth JL. Rap1GAP impairs cell-matrix adhesion in the absence of effects on cell-cell adhesion. Cell Adhesion & Migration. 5: 323-31. PMID 21785277 DOI: 10.4161/Cam.5.4.17041  0.772
2011 Dong X, Korch C, Meinkoth JL. Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells. Endocrine-Related Cancer. 18: 301-10. PMID 21367844 DOI: 10.1530/Erc-10-0320  0.519
2011 Rhee SS, Lim B, Kim H, Wang Y, Aziz U, Butt U, Tang W, Vuchak LA, DeMichele A, Troxel AB, Feldman MD, Meinkoth JL, Brose MS. Abstract 3840: Rap1 GTPase activating protein (Rap1GAP) is downregulated in DCIS and invasive ductal carcinoma Cancer Research. 71: 3840-3840. DOI: 10.1158/1538-7445.Am2011-3840  0.742
2010 Tsygankova OM, Ma C, Tang W, Korch C, Feldman MD, Lv Y, Brose MS, Meinkoth JL. Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion. Molecular and Cellular Biology. 30: 3262-74. PMID 20439492 DOI: 10.1128/Mcb.01345-09  0.542
2010 Mei Y, Yong J, Liu H, Shi Y, Meinkoth J, Dreyfuss G, Yang X. tRNA binds to cytochrome c and inhibits caspase activation. Molecular Cell. 37: 668-78. PMID 20227371 DOI: 10.1016/J.Molcel.2010.01.023  0.416
2009 Vuchak LA, Tsygankova OM, Prendergast GV, Meinkoth JL. Protein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropin. Molecular Pharmacology. 76: 1123-9. PMID 19720729 DOI: 10.1124/Mol.109.060129  0.784
2009 Nellore A, Paziana K, Ma C, Tsygankova OM, Wang Y, Puttaswamy K, Iqbal AU, Franks SR, Lv Y, Troxel AB, Feldman MD, Meinkoth JL, Brose MS. Loss of Rap1GAP in papillary thyroid cancer. The Journal of Clinical Endocrinology and Metabolism. 94: 1026-32. PMID 19066305 DOI: 10.1210/jc.2008-1042  0.47
2008 Nellore A, Paziana K, Tsgankova OM, Wang Y, Lv Y, Puttaswamy K, Troxel AB, Feldman MD, Meinkoth JL, Brose MS. Progressive loss of Rap1GAP in benign and invasive thyroid cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 6059. PMID 27950576 DOI: 10.1200/Jco.2008.26.15_Suppl.6059  0.526
2007 Tsygankova OM, Prendergast GV, Puttaswamy K, Wang Y, Feldman MD, Wang H, Brose MS, Meinkoth JL. Downregulation of Rap1GAP contributes to Ras transformation. Molecular and Cellular Biology. 27: 6647-58. PMID 17646383 DOI: 10.1128/Mcb.00155-07  0.584
2006 Abulaiti A, Fikaris AJ, Tsygankova OM, Meinkoth JL. Ras induces chromosome instability and abrogation of the DNA damage response. Cancer Research. 66: 10505-12. PMID 17079472 DOI: 10.1158/0008-5472.Can-06-2351  0.779
2006 Fikaris AJ, Lewis AE, Abulaiti A, Tsygankova OM, Meinkoth JL. Ras triggers ataxia-telangiectasia-mutated and Rad-3-related activation and apoptosis through sustained mitogenic signaling Journal of Biological Chemistry. 281: 34759-34767. PMID 16968694 DOI: 10.1074/Jbc.M606737200  0.804
2006 Wang Q, Du X, Meinkoth J, Hirohashi Y, Zhang H, Liu Q, Richter M, Greene MI. Characterization of Su48, a centrosome protein essential for cell division. Proceedings of the National Academy of Sciences of the United States of America. 103: 6512-7. PMID 16617106 DOI: 10.1073/pnas.0601682103  0.333
2006 Dworet JH, Meinkoth JL. Interference with 3',5'-cyclic adenosine monophosphate response element binding protein stimulates apoptosis through aberrant cell cycle progression and checkpoint activation. Molecular Endocrinology (Baltimore, Md.). 20: 1112-20. PMID 16410315 DOI: 10.1210/Me.2005-0386  0.818
2005 Santiago-Walker AE, Fikaris AJ, Kao GD, Brown EJ, Kazanietz MG, Meinkoth JL. Protein kinase C δ stimulates apoptosis by initiating G1 phase cell cycle progression and S phase arrest Journal of Biological Chemistry. 280: 32107-32114. PMID 16051606 DOI: 10.1074/Jbc.M504432200  0.778
2004 Meinkoth JL. Biology of Ras in thyroid cells. Cancer Treatment and Research. 122: 131-48. PMID 16209042 DOI: 10.1007/1-4020-8107-3_7  0.484
2004 Lewis AE, Fikaris AJ, Prendergast GV, Meinkoth JL. Thyrotropin and serum regulate thyroid cell proliferation through differential effects on p27 expression and localization Molecular Endocrinology. 18: 2321-2332. PMID 15166254 DOI: 10.1210/Me.2004-0104  0.798
2004 Gurvich N, Tsygankova OM, Meinkoth JL, Klein PS. Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Research. 64: 1079-86. PMID 14871841 DOI: 10.1158/0008-5472.Can-03-0799  0.329
2004 Tsygankova OM, Feshchenko E, Klein PS, Meinkoth JL. Thyroid-stimulating hormone/cAMP and glycogen synthase kinase 3beta elicit opposing effects on Rap1GAP stability. The Journal of Biological Chemistry. 279: 5501-7. PMID 14660640 DOI: 10.1074/Jbc.M305824200  0.555
2003 Cheng G, Lewis AE, Meinkoth JL. Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells Molecular Endocrinology. 17: 450-459. PMID 12554771 DOI: 10.1210/Me.2002-0344  0.609
2003 Li Y, Gonzalez MI, Meinkoth JL, Field J, Kazanietz MG, Tennekoon GI. Lysophosphatidic acid promotes survival and differentiation of rat Schwann cells. The Journal of Biological Chemistry. 278: 9585-91. PMID 12524451 DOI: 10.1074/Jbc.M213244200  0.534
2003 Meinkoth JL. Methods in Enzymology, Vol. 333, Regulators and Effectors of small GTPases. Part G. Ras Family II Analytical Biochemistry. 312: 262-263. DOI: 10.1016/S0003-2697(02)00459-1  0.325
2002 Saavedra AP, Tsygankova OM, Prendergast GV, Dworet JH, Cheng G, Meinkoth JL. Role of cAMP, PKA and Rap1A in thyroid follicular cell survival. Oncogene. 21: 778-88. PMID 11850806 DOI: 10.1038/Sj.Onc.1205123  0.786
2002 Mei FC, Qiao J, Tsygankova OM, Meinkoth JL, Quilliam LA, Cheng X. Differential signaling of cyclic AMP: opposing effects of exchange protein directly activated by cyclic AMP and cAMP-dependent protein kinase on protein kinase B activation. The Journal of Biological Chemistry. 277: 11497-504. PMID 11801596 DOI: 10.1074/Jbc.M110856200  0.491
2001 Cheng G, Meinkoth JL. Enhanced sensitivity to apoptosis in Ras-transformed thyroid cells. Oncogene. 20: 7334-41. PMID 11704863 DOI: 10.1038/Sj.Onc.1204928  0.569
2001 Tsygankova OM, Saavedra A, Rebhun JF, Quilliam LA, Meinkoth JL. Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A. Molecular and Cellular Biology. 21: 1921-9. PMID 11238928 DOI: 10.1128/Mcb.21.6.1921-1929.2001  0.787
2000 Saavedra AP, Cass LA, Prendergast GV, Meinkoth JL. Differential Effects of Acute and Chronic Exposure to Interferon-γ on Cyclic Adenosine 3',5'-Monophosphate Response Element-Regulated Gene Expression1. Endocrinology. 141: 606-614. PMID 28204398 DOI: 10.1210/endo.141.2.7301  0.625
2000 Fernandez N, Caloca MA, Prendergast GV, Meinkoth JL, Kazanietz MG. Atypical Protein Kinase C-ζ Stimulates Thyrotropin-Independent Proliferation in Rat Thyroid Cells1. Endocrinology. 141: 146-152. PMID 28200778 DOI: 10.1210/Endo.141.1.7278  0.63
2000 Zhou H, Li XM, Meinkoth J, Pittman RN. Akt regulates cell survival and apoptosis at a postmitochondrial level. The Journal of Cell Biology. 151: 483-94. PMID 11062251 DOI: 10.1083/Jcb.151.3.483  0.522
2000 Tsygankova OM, Kupperman E, Wen W, Meinkoth JL. Cyclic AMP activates Ras. Oncogene. 19: 3609-15. PMID 10951566 DOI: 10.1038/Sj.Onc.1203680  0.526
2000 Cass LA, Meinkoth JL. Ras signaling through PI3K confers hormone-independent proliferation that is compatible with differentiation. Oncogene. 19: 924-32. PMID 10702801 DOI: 10.1038/Sj.Onc.1203393  0.557
2000 Saavedra AP, Cass LA, Prendergast GV, Meinkoth JL. Differential effects of acute and chronic exposure to interferon-gamma on cyclic adenosine 3',5'-monophosphate response element-regulated gene expression. Endocrinology. 141: 606-14. PMID 10650941 DOI: 10.1210/Endo.141.2.7301  0.776
1999 Cass LA, Summers SA, Prendergast GV, Backer JM, Birnbaum MJ, Meinkoth JL. Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation Molecular and Cellular Biology. 19: 5882-5891. PMID 10454535 DOI: 10.1128/Mcb.19.9.5882  0.53
1998 Kunapuli P, Lawson JA, Rokach JA, Meinkoth JL, FitzGerald GA. Prostaglandin F2alpha (PGF2alpha) and the isoprostane, 8, 12-iso-isoprostane F2alpha-III, induce cardiomyocyte hypertrophy. Differential activation of downstream signaling pathways. The Journal of Biological Chemistry. 273: 22442-52. PMID 9712868 DOI: 10.1074/jbc.273.35.22442  0.304
1998 Miller MJ, Rioux L, Prendergast GV, Cannon S, White MA, Meinkoth JL. Differential effects of protein kinase A on Ras effector pathways. Molecular and Cellular Biology. 18: 3718-26. PMID 9632754 DOI: 10.1128/Mcb.18.7.3718  0.55
1998 Cass LA, Meinkoth JL. Differential effects of cyclic adenosine 3',5'-monophosphate on p70 ribosomal S6 kinase. Endocrinology. 139: 1991-8. PMID 9528986 DOI: 10.1210/Endo.139.4.5880  0.59
1997 Miller MJ, Prigent S, Kupperman E, Rioux L, Park SH, Feramisco JR, White MA, Rutkowski JL, Meinkoth JL. RalGDS functions in Ras- and cAMP-mediated growth stimulation. The Journal of Biological Chemistry. 272: 5600-5. PMID 9038168 DOI: 10.1074/Jbc.272.9.5600  0.523
1996 Kupperman E, Wofford D, Wen W, Meinkoth JL. Ras inhibits thyroglobulin expression but not cyclic adenosine monophosphate-mediated signaling in Wistar rat thyrocytes. Endocrinology. 137: 96-104. PMID 8536648 DOI: 10.1210/endo.137.1.8536648  0.366
1995 Armstrong R, Wen W, Meinkoth J, Taylor S, Montminy M. A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A. Molecular and Cellular Biology. 15: 1826-32. PMID 7862172 DOI: 10.1128/Mcb.15.3.1826  0.382
1995 al-Alawi N, Rose DW, Buckmaster C, Ahn N, Rapp U, Meinkoth J, Feramisco JR. Thyrotropin-induced mitogenesis is Ras dependent but appears to bypass the Raf-dependent cytoplasmic kinase cascade. Molecular and Cellular Biology. 15: 1162-8. PMID 7862110 DOI: 10.1128/Mcb.15.3.1162  0.494
1995 Wen W, Taylor SS, Meinkoth JL. The expression and intracellular distribution of the heat-stable protein kinase inhibitor is cell cycle regulated Journal of Biological Chemistry. 270: 2041-2046. PMID 7836431 DOI: 10.1074/Jbc.270.5.2041  0.537
1994 Solberg R, Taskén K, Wen W, Coghlan VM, Meinkoth JL, Scott JD, Jahnsen T, Taylor SS. Human regulatory subunit RI beta of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells. Experimental Cell Research. 214: 595-605. PMID 7925653 DOI: 10.1006/Excr.1994.1297  0.313
1993 Sorscher SM, Steeg P, Feramisco JR, Buckmaster C, Boss GR, Meinkoth J. Microinjection of an nm23 specific antibody inhibits cell division in rat embryo fibroblasts. Biochemical and Biophysical Research Communications. 195: 336-45. PMID 8395830 DOI: 10.1006/bbrc.1993.2049  0.345
1993 Alberts AS, Deng T, Lin A, Meinkoth JL, Schönthal A, Mumby MC, Karin M, Feramisco JR. Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements. Molecular and Cellular Biology. 13: 2104-12. PMID 8384305 DOI: 10.1128/Mcb.13.4.2104  0.312
1993 Kupperman E, Wen W, Meinkoth JL. Inhibition of thyrotropin-stimulated DNA synthesis by microinjection of inhibitors of cellular Ras and cyclic AMP-dependent protein kinase. Molecular and Cellular Biology. 13: 4477-84. PMID 8336696 DOI: 10.1128/MCB.13.8.4477  0.416
1993 Meinkoth JL, Alberts AS, Went W, Fantozzi D, Taylor SS, Hagiwara M, Montminy M, Feramisco JR. Signal transduction through the cAMP-dependent protein kinase. Molecular and Cellular Biochemistry. 127: 179-86. PMID 7935349 DOI: 10.1007/Bf01076769  0.34
1992 Hagiwara M, Alberts A, Brindle P, Meinkoth J, Feramisco J, Deng T, Karin M, Shenolikar S, Montminy M. Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. Cell. 70: 105-13. PMID 1352481 DOI: 10.1016/0092-8674(92)90537-M  0.443
1991 Meinkoth JL, Montminy MR, Fink JS, Feramisco JR. Induction of a cyclic AMP-responsive gene in living cells requires the nuclear factor CREB. Molecular and Cellular Biology. 11: 1759-64. PMID 1847503  0.32
1990 Meinkoth J, Alberts AS, Feramisco JR. Construction of mammalian cell lines with indicator genes driven by regulated promoters. Ciba Foundation Symposium. 150: 47-51; discussion 51. PMID 2164909  0.365
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