Cathleen R. Carlin - Publications

Affiliations: 
Case Western Reserve University School of Medicine, Cleveland, OH, United States 
Area:
Cell Biology, Molecular Biology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Carlin CR, Ngalula S. Loss of EGF receptor polarity enables homeostatic imbalance in epithelial cell models. Molecular Biology of the Cell. mbcE23040133. PMID 37647145 DOI: 10.1091/mbc.E23-04-0133  0.459
2022 Carlin CR. Role of EGF Receptor Regulatory Networks in the Host Response to Viral Infections. Frontiers in Cellular and Infection Microbiology. 11: 820355. PMID 35083168 DOI: 10.3389/fcimb.2021.820355  0.4
2020 Carlin C, Manor D. Adenovirus Reveals New Pathway for Cholesterol Egress from the Endolysosomal System. International Journal of Molecular Sciences. 21. PMID 32823559 DOI: 10.3390/Ijms21165808  0.358
2019 Zeng X, Carlin CR. Adenovirus early region 3 RIDa protein limits NFκB signaling through stress-activated EGF receptors. Plos Pathogens. 15: e1008017. PMID 31425554 DOI: 10.1371/Journal.Ppat.1008017  0.498
2019 Carlin CR. New Insights to Adenovirus-Directed Innate Immunity in Respiratory Epithelial Cells. Microorganisms. 7. PMID 31349602 DOI: 10.3390/microorganisms7080216  0.393
2018 Muller-Greven G, Marin B, Carlin C, Reilly E, Lee J, Bredel M, Sarkaria J, Gladson C. CADD-57. THE EFFICACY OF THERAPY WITH ABT-414, AN EGFR-TARGETING ADC, IS POTENTIALLY ALTERED BY HETEROZYGOUS DELETION OF THE ENDOCYTIC TRAFFICKING REGULATOR RBSN Neuro-Oncology. 20: vi283-vi284. DOI: 10.1093/Neuonc/Noy148.1182  0.325
2017 Balanis N, Carlin CR. Stress-induced EGF receptor signaling through STAT3 and tumor progression in triple-negative breast cancer. Molecular and Cellular Endocrinology. PMID 28088463 DOI: 10.1016/J.Mce.2017.01.013  0.382
2017 Cianciola NL, Chung S, Manor D, Carlin CR. Adenovirus modulates Toll-like receptor 4 signaling by reprogramming ORP1L-VAP protein contacts for cholesterol transport from endosomes to the endoplasmic reticulum. Journal of Virology. PMID 28077646 DOI: 10.1128/Jvi.01904-16  0.456
2016 Chung S, Gehlfi M, Atkinson J, Parker R, Qian J, Carlin C, Manor D. Vitamin E and phosphoinositides regulate the intracellular localization of the hepatic α-tocopherol transfer protein. The Journal of Biological Chemistry. PMID 27307040 DOI: 10.1074/Jbc.M116.734210  0.307
2016 Muller-Greven G, Carlin C, Toms S, Ahluwalia M, Bredel M, Lathia J, Rich J, Hamerlik P, Gladson CL. Abstract 3276: The tissue and cellular destination of therapeutic IgGs in glioblastoma Cancer Research. 76: 3276-3276. DOI: 10.1158/1538-7445.Am2016-3276  0.346
2015 Wendt MK, Williams WK, Pascuzzi PE, Balanis NG, Schiemann BJ, Carlin CR, Schiemann WP. The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6. Neoplasia (New York, N.Y.). 17: 124-33. PMID 25622905 DOI: 10.1016/J.Neo.2014.11.009  0.41
2014 Muller-Greven GM, Carlin C, Rich J, Hamerlik P, Gladson CL. Abstract LB-65: Bevacizumab fate in glioblastoma: Mechanism of internalization by endothelial cells and glioma stem cells Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-65  0.303
2014 Muller-Greven G, Carlin C, Lathia J, Rich J, Hamerlik P, Gladson C. SC-22 * GLIOMA STEM CELLS INTERNALIZE BEVACIZUMAB FOUND IN THE PERIVASCULAR NICHE AND TARGET IT FOR RECYCLING OR DEGRADATION Neuro-Oncology. 16: v201-v201. DOI: 10.1093/Neuonc/Nou275.22  0.304
2013 Muniz-Feliciano L, Van Grol J, Portillo JA, Liew L, Liu B, Carlin CR, Carruthers VB, Matthews S, Subauste CS. Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite. Plos Pathogens. 9: e1003809. PMID 24367261 DOI: 10.1371/Journal.Ppat.1003809  0.393
2013 Cianciola NL, Greene DJ, Morton RE, Carlin CR. Adenovirus RIDα uncovers a novel pathway requiring ORP1L for lipid droplet formation independent of NPC1. Molecular Biology of the Cell. 24: 3309-25. PMID 24025716 DOI: 10.1091/Mbc.E12-10-0760  0.341
2013 Balanis N, Wendt MK, Schiemann BJ, Wang Z, Schiemann WP, Carlin CR. Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway. The Journal of Biological Chemistry. 288: 17954-67. PMID 23653350 DOI: 10.1074/Jbc.M113.475277  0.431
2013 Zeng X, Carlin CR. Host cell autophagy modulates early stages of adenovirus infections in airway epithelial cells. Journal of Virology. 87: 2307-19. PMID 23236070 DOI: 10.1128/Jvi.02014-12  0.415
2013 Cotton CU, Hobert ME, Ryan S, Carlin CR. Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells. Traffic (Copenhagen, Denmark). 14: 337-54. PMID 23205726 DOI: 10.1111/Tra.12032  0.485
2013 Zhang P, Guo A, Possemato A, Wang C, Beard L, Carlin C, Markowitz SD, Polakiewicz RD, Wang Z. Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14. Oncogene. 32: 2087-95. PMID 22710723 DOI: 10.1038/Onc.2012.220  0.391
2013 Wendt MK, Balanis N, Schiemann B, Carlin C, Schiemann W. Abstract A17: Regulation of EGFR: Stat3 signaling by Mig6 is required for metastatic outgrowth in triple-negative breast cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A17  0.402
2013 Muller-Greven GM, Carlin C, Gladson CL. Abstract LB-340: Mechanism of bevacizumab internalization and fate by brain endothelial cells . Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-340  0.354
2012 Balanis N, Carlin CR. Mutual cross-talk between fibronectin integrins and the EGF receptor: Molecular basis and biological significance. Cellular Logistics. 2: 46-51. PMID 22645710 DOI: 10.4161/Cl.20112  0.637
2012 Wendt MK, Balanis N, Carlin C, Schiemann W. Abstract A24: Fibronectin-mediated activation of Stat3 facilitates the resistance of triple negative breast cancer to EGFR-targeted therapies Clinical Cancer Research. 18: A24-A24. DOI: 10.1158/1078-0432.Mechres-A24  0.423
2011 Balanis N, Yoshigi M, Wendt MK, Schiemann WP, Carlin CR. β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells. Molecular Biology of the Cell. 22: 4288-301. PMID 21937717 DOI: 10.1091/Mbc.E10-08-0700  0.496
2011 Cianciola NL, Carlin CR, Kelley TJ. Molecular pathways for intracellular cholesterol accumulation: common pathogenic mechanisms in Niemann-Pick disease Type C and cystic fibrosis. Archives of Biochemistry and Biophysics. 515: 54-63. PMID 21924233 DOI: 10.1016/J.Abb.2011.08.012  0.308
2010 Ryan S, Verghese S, Cianciola NL, Cotton CU, Carlin CR. Autosomal recessive polycystic kidney disease epithelial cell model reveals multiple basolateral epidermal growth factor receptor sorting pathways. Molecular Biology of the Cell. 21: 2732-45. PMID 20519437 DOI: 10.1091/Mbc.E09-12-1059  0.541
2010 Cianciola NL, Carlin CR. Adenovirus RIDalpha protein reveals novel autophagic mechanism that regulates cholesterol homeostasis. Autophagy. 6: 296-8. PMID 20139720 DOI: 10.4161/Auto.6.2.11130  0.433
2009 Cianciola NL, Carlin CR. Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. The Journal of Cell Biology. 187: 537-52. PMID 19948501 DOI: 10.1083/Jcb.200903039  0.343
2008 Hake MJ, Choowongkomon K, Kostenko O, Carlin CR, Sönnichsen FD. Specificity determinants of a novel Nck interaction with the juxtamembrane domain of the epidermal growth factor receptor. Biochemistry. 47: 3096-108. PMID 18269246 DOI: 10.1021/Bi701549A  0.492
2007 Shah AH, Cianciola NL, Mills JL, Sönnichsen FD, Carlin C. Adenovirus RIDalpha regulates endosome maturation by mimicking GTP-Rab7. The Journal of Cell Biology. 179: 965-80. PMID 18039930 DOI: 10.1083/Jcb.200702187  0.483
2007 Cianciola NL, Crooks D, Shah AH, Carlin C. A tyrosine-based signal plays a critical role in the targeting and function of adenovirus RIDalpha protein. Journal of Virology. 81: 10437-50. PMID 17634224 DOI: 10.1128/Jvi.00399-07  0.795
2006 Kostenko O, Tsacoumangos A, Crooks D, Kil SJ, Carlin C. Gab1 signaling is regulated by EGF receptor sorting in early endosomes Oncogene. 25: 6604-6617. PMID 16715136 DOI: 10.1038/Sj.Onc.1209675  0.725
2005 Tsacoumangos A, Tsacoumango A, Kil SJ, Ma L, Sönnichsen FD, Carlin C. A novel dileucine lysosomal-sorting-signal mediates intracellular EGF-receptor retention independently of protein ubiquitylation. Journal of Cell Science. 118: 3959-71. PMID 16105874 DOI: 10.1242/Jcs.02527  0.77
2005 Choowongkomon K, Carlin CR, Sönnichsen FD. A structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor. The Journal of Biological Chemistry. 280: 24043-52. PMID 15840573 DOI: 10.1074/Jbc.M502698200  0.52
2004 Choowongkomon K, Hobert ME, He C, Carlin CR, Sonnichsen FD. Aqueous and micelle-bound structural characterization of the epidermal growth factor receptor juxtamembrane domain containing basolateral sorting motifs. Journal of Biomolecular Structure & Dynamics. 21: 813-26. PMID 15107003 DOI: 10.1080/07391102.2004.10506971  0.583
2003 Kusner L, Carlin C. Potential role for a novel AP180-related protein during endocytosis in MDCK cells American Journal of Physiology - Cell Physiology. 285. PMID 14532018 DOI: 10.1152/Ajpcell.00079.2003  0.379
2002 He C, Hobert M, Friend L, Carlin C. The epidermal growth factor receptor juxtamembrane domain has multiple basolateral plasma membrane localization determinants, including a dominant signal with a polyproline core Journal of Biological Chemistry. 277: 38284-38293. PMID 12161422 DOI: 10.1074/jbc.M104646200  0.532
2001 Sweeney WE, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Dell KM, Avner ED. Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. American Journal of Physiology. Cell Physiology. 281: C1695-705. PMID 11600434 DOI: 10.1152/Ajpcell.2001.281.5.C1695  0.335
2000 Crooks D, Kil SJ, McCaffery JM, Carlin C. E3-13.7 Integral membrane proteins encoded by human adenoviruses alter epidermal growth factor receptor trafficking by interacting directly with receptors in early endosomes Molecular Biology of the Cell. 11: 3559-3572. PMID 11029055 DOI: 10.1091/Mbc.11.10.3559  0.735
1999 Hobert ME, Friend LA, Carlin CR. Regulation of EGF signaling by cell polarity in MDCK kidney epithelial cells Journal of Cellular Physiology. 181: 330-341. PMID 10497312 DOI: 10.1002/(Sici)1097-4652(199911)181:2<330::Aid-Jcp15>3.0.Co;2-S  0.639
1999 Kil SJ, Hobert M, Carlin C. A leucine-based determinant in the epidermal growth factor receptor juxtamembrane domain is required for the efficient transport of ligand- receptor complexes to lysosomes Journal of Biological Chemistry. 274: 3141-3150. PMID 9915853 DOI: 10.1074/Jbc.274.5.3141  0.782
1998 Vinogradova O, Carlin C, Sonnichsen FD, Sanders CR. A membrane setting for the sorting motifs present in the adenovirus E3- 13.7 protein which down-regulates the epidermal growth factor receptor Journal of Biological Chemistry. 273: 17343-17350. PMID 9651317 DOI: 10.1074/Jbc.273.28.17343  0.504
1997 Hobert ME, Kil SJ, Medof ME, Carlin CR. The cytoplasmic juxtamembrane domain of the epidermal growth factor receptor contains a novel autonomous basolateral sorting determinant. The Journal of Biological Chemistry. 272: 32901-9. PMID 9407068 DOI: 10.1074/Jbc.272.52.32901  0.765
1995 Hobert M, Carlin C. Cytoplasmic juxtamembrane domain of the human EGF receptor is required for basolateral localization in MDCK cells Journal of Cellular Physiology. 162: 434-446. PMID 7860650 DOI: 10.1002/Jcp.1041620316  0.58
1994 Hoffman P, Carlin C. Adenovirus E3 protein causes constitutively internalized epidermal growth factor receptors to accumulate in a prelysosomal compartment, resulting in enhanced degradation Molecular and Cellular Biology. 14: 3695-3706. PMID 8196613 DOI: 10.1128/mcb.14.6.3695-3706.1994  0.574
1994 Carlin C, Phillips PD, Brooks-Frederich K, Knowles BB, Cristofalo VJ. Cleavage of the epidermal growth factor receptor by a membrane-bound leupeptin-sensitive protease active in nonionic detergent lysates of senescent but not young human diploid fibroblasts. Journal of Cellular Physiology. 160: 427-34. PMID 8077280 DOI: 10.1002/Jcp.1041600305  0.619
1993 Hoffman BL, Takishima K, Rosner MR, Carlin C. Adenovirus and protein kinase C have distinct molecular requirements for regulating epidermal growth factor receptor trafficking. Journal of Cellular Physiology. 157: 535-43. PMID 8253865 DOI: 10.1002/Jcp.1041570313  0.599
1993 Kuivinen E, Hoffman BL, Hoffman PA, Carlin CR. Structurally related class I and class II receptor protein tyrosine kinases are down-regulated by the same E3 protein coded for by human group C adenoviruses. The Journal of Cell Biology. 120: 1271-9. PMID 8094718 DOI: 10.1083/Jcb.120.5.1271  0.533
1992 Hoffman P, Rajakumar P, Hoffman B, Heuertz R, Wold WSM, Carlin CR. Evidence for intracellular down-regulation of the epidermal growth factor (EGF) receptor during adenovirus infection by an EGF-independent mechanism Journal of Virology. 66: 197-203. PMID 1727483 DOI: 10.1128/Jvi.66.1.197-203.1992  0.538
1992 Krajcsi P, Tollefson AE, Anderson CW, Stewart AR, Carlin CR, Wold WS. The E3-10.4K protein of adenovirus is an integral membrane protein that is partially cleaved between Ala22 and Ala23 and has a Ccyt orientation. Virology. 187: 131-44. PMID 1531278 DOI: 10.1016/0042-6822(92)90302-6  0.379
1992 Dou Y, Hoffman P, Hoffman BL, Carlin C. Ligand-induced protein tyrosine kinase activity in living cells coexpressing intact EGF receptors and receptors with an extensive cytosolic deletion. Journal of Cellular Physiology. 153: 402-7. PMID 1429858 DOI: 10.1002/Jcp.1041530220  0.615
1990 Hoffman BL, Ullrich A, Wold WS, Carlin CR. Retrovirus-mediated transfer of an adenovirus gene encoding an integral membrane protein is sufficient to down regulate the receptor for epidermal growth factor. Molecular and Cellular Biology. 10: 5521-4. PMID 2398898 DOI: 10.1128/mcb.10.10.5521-5524.1990  0.583
1990 Tollefson AE, Krajcsi P, Yei SP, Carlin CR, Wold WS. A 10,400-molecular-weight membrane protein is coded by region E3 of adenovirus. Journal of Virology. 64: 794-801. PMID 2296083 DOI: 10.1128/Jvi.64.2.794-801.1990  0.358
1989 Carlin CR, Tollefson AE, Brady HA, Hoffman BL, Wold WS. Epidermal growth factor receptor is down-regulated by a 10,400 MW protein encoded by the E3 region of adenovirus. Cell. 57: 135-44. PMID 2522818 DOI: 10.1016/0092-8674(89)90179-7  0.484
1988 Carlin CR, Simon D, Mattison J, Knowles BB. Expression and biosynthetic variation of the epidermal growth factor receptor in human hepatocellular carcinoma-derived cell lines Molecular and Cellular Biology. 8: 25-34. PMID 2827003 DOI: 10.1128/mcb.8.1.25-34.1988  0.451
1987 Brooks KM, Phillips PD, Carlin CR, Knowles BB, Cristofalo VJ. EGF-dependent phosphorylation of the EGF receptor in plasma membranes isolated from young and senescent WI-38 cells. Journal of Cellular Physiology. 133: 523-31. PMID 3320064 DOI: 10.1002/Jcp.1041330313  0.484
1986 Carlin CR, Knowles BB. Biosynthesis and glycosylation of the epidermal growth factor receptor in human tumor-derived cell lines A431 and Hep 3B Molecular and Cellular Biology. 6: 257-264. PMID 3023826 DOI: 10.1128/mcb.6.1.257-264.1986  0.329
1985 Carlin CR, Andrews PW. Human embryonal carcinoma cells express low levels of functional receptor for epidermal growth factor Experimental Cell Research. 159: 17-26. PMID 2993003 DOI: 10.1016/S0014-4827(85)80033-1  0.409
1983 Carlin CR, Phillips PD, Knowles BB, Cristofalo VJ. Diminished in vitro tyrosine kinase activity of the EGF receptor of senescent human fibroblasts. Nature. 306: 617-20. PMID 6316166 DOI: 10.1038/306617A0  0.462
1982 Carlin CR, Knowles BB. Identity of human epidermal growth factor (EGF) receptor with glycoprotein SA-7: Evidence for differential phosphorylation of the two components of the EGF receptor from A431 cells Proceedings of the National Academy of Sciences of the United States of America. 79: 5026-5030. PMID 6289330 DOI: 10.1073/Pnas.79.16.5026  0.426
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