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Harold L. Moses, M.D. - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Cell Biology
Website:
http://www.vicc.org/dd/display.php?person=hal.moses

249 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hara H, Maemura S, Fujiwara T, Takeda N, Ishii S, Yagi H, Suzuki T, Harada M, Toko H, Kanaya T, Ijichi H, Moses HL, Takimoto E, Morita H, Akazawa H, et al. Inhibition of transforming growth factor-β signaling in myeloid cells ameliorates aortic aneurysmal formation in Marfan syndrome. Plos One. 15: e0239908. PMID 33175881 DOI: 10.1371/journal.pone.0239908  0.303
2020 Vasiukov G, Novitskaya T, Zijlstra A, Owens P, Ye F, Zhao Z, Moses HL, Blackwell T, Feoktistov I, Novitskiy SV. Myeloid cell-derived TGF-beta signaling regulates ECM deposition in mammary carcinoma via adenosine-dependent mechanisms. Cancer Research. PMID 32312837 DOI: 10.1158/0008-5472.Can-19-3954  0.489
2020 Vasiukov G, Novitskaya T, Schwager S, Moses H, Blackwell T, Feoktistov I, Novitskiy S. Abstract 1714A: TGF-beta signaling on myeloid cells regulates ECM deposition in mammary carcinoma via adenosine dependent mechanisms Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-1714A  0.577
2019 Sano M, Ijichi H, Takahashi R, Miyabayashi K, Fujiwara H, Yamada T, Kato H, Nakatsuka T, Tanaka Y, Tateishi K, Morishita Y, Moses HL, Isayama H, Koike K. Blocking CXCLs-CXCR2 axis in tumor-stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment. Oncogenesis. 8: 8. PMID 30659170 DOI: 10.1038/s41389-018-0117-8  0.302
2018 Raz Y, Cohen N, Shani O, Bell RE, Novitskiy SV, Abramovitz L, Levy C, Milyavsky M, Leider-Trejo L, Moses HL, Grisaru D, Erez N. Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. The Journal of Experimental Medicine. PMID 30470719 DOI: 10.1084/Jem.20180818  0.379
2017 Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL, Novitskiy SV. Development of aggressive pancreatic ductal adenocarcinomas depends on granulocyte-colony stimulating factor secretion in carcinoma cells. Cancer Immunology Research. PMID 28775207 DOI: 10.1158/2326-6066.Cir-16-0311  0.389
2017 Polosukhina D, Love H, Moses H, Lee E, Zent R, Clark P. Pharmacologic Inhibition of ß-catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor. Oncology Research. PMID 28695795 DOI: 10.3727/096504017X14992942781895  0.431
2017 Polosukhina D, Love HD, Correa H, Su Z, Dahlman KB, Pao W, Moses HL, Arteaga CL, Lovvorn HN, Zent R, Clark PE. Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms Tumors. Molecular Oncology. PMID 28188683 DOI: 10.1002/1878-0261.12044  0.452
2017 Pickup MW, Owens P, Moses HL. TGF-β, Bone Morphogenetic Protein, and Activin Signaling and the Tumor Microenvironment. Cold Spring Harbor Perspectives in Biology. PMID 28062564 DOI: 10.1101/Cshperspect.A022285  0.486
2016 Sai J, Owens P, Novitiskiy SV, Hawkins OE, Vilgelm AE, Yang J, Sobolik-Delmaire T, Lavender N, Johnson AC, McClain C, Ayers GD, Kelley MC, Sanders M, Mayer IA, Moses HL, et al. PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Anti-tumor Immunity and Anti-PD1 Responses. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28003307 DOI: 10.1158/1078-0432.Ccr-16-2142  0.399
2016 Jovanović B, Pickup MW, Chytil A, Gorska AE, Johnson KC, Moses HL, Owens P. TβRIII Expression in Human Breast Cancer Stroma and the Role of Soluble TβRIII in Breast Cancer Associated Fibroblasts. Cancers. 8. PMID 27827906 DOI: 10.3390/Cancers8110100  0.437
2016 Moses HL, Roberts AB, Derynck R. The Discovery and Early Days of TGF-β: A Historical Perspective. Cold Spring Harbor Perspectives in Biology. PMID 27328871 DOI: 10.1101/Cshperspect.A021865  0.474
2016 Lehmann BD, Jovanović B, Chen X, Estrada MV, Johnson KN, Shyr Y, Moses HL, Sanders ME, Pietenpol JA. Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection. Plos One. 11: e0157368. PMID 27310713 DOI: 10.1371/Journal.Pone.0157368  0.303
2016 Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, ... ... Moses HL, et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 27089513 DOI: 10.1038/Nm.4082  0.478
2016 Ampuja M, Alarmo EL, Owens P, Havunen R, Gorska AE, Moses HL, Kallioniemi A. The impact of bone morphogenetic protein 4 (BMP4) on breast cancer metastasis in a mouse xenograft model. Cancer Letters. 375: 238-44. PMID 26970275 DOI: 10.1016/J.Canlet.2016.03.008  0.355
2016 Jolly LA, Novitskiy SV, Owens P, Massoll N, Cheng N, Fang W, Moses HL, Franco AT. Fibroblast-mediated collagen remodeling within the tumor microenvironment facilitates progression of thyroid cancers driven by BrafV600E and Pten loss. Cancer Research. PMID 26818109 DOI: 10.1158/0008-5472.Can-15-2351  0.375
2016 Ampuja M, Alarmo EL, Owens P, Havunen R, Gorska AE, Moses HL, Kallioniemi A. Abstract 629: The impact of BMP4 on breast cancer metastasis in an in vivo xenograft mouse model Cancer Research. 76: 629-629. DOI: 10.1158/1538-7445.Am2016-629  0.396
2016 Ijichi H, Miyabayashi K, Takahashi R, Tateishi K, Tada M, Isayama H, Moses HL, Koike K. Crucial roles of BMP signaling in pancreatic cancer initiation and progression Pancreatology. 16: S28-S29. DOI: 10.1016/J.Pan.2016.06.113  0.336
2015 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... Moses HL, et al. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 28: 831-833. PMID 28843279 DOI: 10.1016/J.Ccell.2015.11.002  0.32
2015 Hover LD, Owens P, Munden AL, Wang J, Chambless LB, Hopkins CR, Hong CC, Moses HL, Abel TW. Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma. Neuro-Oncology. PMID 26683138 DOI: 10.1093/Neuonc/Nov310  0.352
2015 Pickup MW, Hover LD, Guo Y, Gorska AE, Chytil A, Novitskiy SV, Moses HL, Owens P. Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis. Oncotarget. PMID 26274893 DOI: 10.18632/Oncotarget.4413  0.477
2015 Nagathihalli NS, Castellanos JA, Shi C, Beesetty Y, Reyzer ML, Caprioli R, Chen X, Walsh AJ, Skala MC, Moses HL, Merchant NB. Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer. Gastroenterology. PMID 26255562 DOI: 10.1053/J.Gastro.2015.07.058  0.369
2015 Hover LD, Young CD, Bhola NE, Wilson AJ, Khabele D, Hong CC, Moses HL, Owens P. Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth. Cancer Letters. PMID 26235139 DOI: 10.1016/J.Canlet.2015.07.032  0.456
2015 Yi Y, Polosukhina D, Love HD, Hembd A, Pickup M, Moses HL, Lovvorn HN, Zent R, Clark PE. A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor. The Journal of Urology. 194: 1762-70. PMID 25934441 DOI: 10.1016/J.Juro.2015.04.090  0.371
2015 Shaw AK, Pickup MW, Chytil A, Aakre M, Owens P, Moses HL, Novitskiy SV. TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. Plos One. 10: e0117908. PMID 25629162 DOI: 10.1371/Journal.Pone.0117908  0.457
2015 Pickup MW, Hover LD, Polikowsky ER, Chytil A, Gorska AE, Novitskiy SV, Moses HL, Owens P. BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation. Molecular Oncology. 9: 179-91. PMID 25205038 DOI: 10.1016/J.Molonc.2014.08.004  0.462
2015 Owens P, Pickup MW, Novitskiy SV, Giltnane JM, Gorska AE, Hopkins CR, Hong CC, Moses HL. Inhibition of BMP signaling suppresses metastasis in mammary cancer. Oncogene. 34: 2437-49. PMID 24998846 DOI: 10.1038/Onc.2014.189  0.452
2015 Jovanovic B, Beeler JS, Pickup MW, Chytil A, Gorska AE, Ashby WJ, Lehmann BD, Zijlstra A, Pietenpol JA, Moses HL. Abstract P6-03-04: TGF-β receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P6-03-04  0.491
2015 Miyabayashi K, Ijichi H, Takahashi R, Yamamoto K, Asaoka Y, Tateishi K, Nakai Y, Isayama H, Moses HL, Koike K. Abstract A55: A role of bone morphogenetic protein signaling in pancreatic cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-A55  0.495
2015 Hover LD, Pickup MW, Gorska AE, Chytil A, Guo Y, Novitskiy SV, Moses HL, Owens P. Abstract 4083: Deletion of the BMP receptor BMPR1a results in EMT and impairs mammary gland tumor formation and metastasis Cancer Research. 75: 4083-4083. DOI: 10.1158/1538-7445.Am2015-4083  0.37
2014 Novitskiy SV, Forrester E, Pickup MW, Gorska AE, Chytil A, Aakre M, Polosukhina D, Owens P, Yusupova DR, Zhao Z, Ye F, Shyr Y, Moses HL. Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis. Breast Cancer Research : Bcr. 16: 425. PMID 25280532 DOI: 10.1186/S13058-014-0425-7  0.833
2014 Andl T, Le Bras GF, Richards NF, Allison GL, Loomans HA, Washington MK, Revetta F, Lee RK, Taylor C, Moses HL, Andl CD. Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma. Carcinogenesis. 35: 2602-10. PMID 25233932 DOI: 10.1093/Carcin/Bgu194  0.459
2014 Ryzhov SV, Pickup MW, Chytil A, Gorska AE, Zhang Q, Owens P, Feoktistov I, Moses HL, Novitskiy SV. Role of TGF-β signaling in generation of CD39+CD73+ myeloid cells in tumors. Journal of Immunology (Baltimore, Md. : 1950). 193: 3155-64. PMID 25127858 DOI: 10.4049/Jimmunol.1400578  0.402
2014 Jovanovi? B, Beeler JS, Pickup MW, Chytil A, Gorska AE, Ashby WJ, Lehmann BD, Zijlstra A, Pietenpol JA, Moses HL. Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer. Breast Cancer Research : Bcr. 16: R69. PMID 24985072 DOI: 10.1186/Bcr3684  0.488
2014 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... Moses HL, et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 25: 719-34. PMID 24856586 DOI: 10.1016/J.Ccr.2014.04.005  0.399
2014 Hansen AG, Arnold SA, Jiang M, Palmer TD, Ketova T, Merkel A, Pickup M, Samaras S, Shyr Y, Moses HL, Hayward SW, Sterling JA, Zijlstra A. ALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to bone. Cancer Research. 74: 1404-15. PMID 24385212 DOI: 10.1158/0008-5472.Can-13-1296  0.397
2014 Miyabayashi K, Ijichi H, Takahashi R, Mohri D, Yamamoto K, Asaoka Y, Ikenoue T, Tateishi K, Moses HL, Koike K. Abstract B10: Epidermal growth factor receptor inhibitor prolongs survival in pancreatic cancer by blocking gemcitabine-induced mitogen-activated protein kinase signal Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B10  0.423
2014 Laklai H, Miroshnikova Y, lakins J, Sergey N, Gorska A, Korets L, Kalluri R, Moses H, Weaver V. Abstract LB-143: Interplay between tissue tension and inflammation in pancreatic tumor progression Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-143  0.405
2014 Owens P, Pickup MW, Novitskiy SV, Giltnane JM, Gorska AE, Hopkins CR, Hong CC, Moses HL. Abstract 2676: Inhibition of bmp signaling suppresses metastasis in mammary cancer Cancer Research. 74: 2676-2676. DOI: 10.1158/1538-7445.Am2014-2676  0.447
2013 Pickup M, Novitskiy S, Moses HL. The roles of TGFβ in the tumour microenvironment. Nature Reviews. Cancer. 13: 788-99. PMID 24132110 DOI: 10.1038/Nrc3603  0.39
2013 Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL. Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas. Cancer Research. 73: 5336-46. PMID 23856251 DOI: 10.1158/0008-5472.Can-13-0012  0.494
2013 Owens P, Polikowsky H, Pickup MW, Gorska AE, Jovanovic B, Shaw AK, Novitskiy SV, Hong CC, Moses HL. Bone Morphogenetic Proteins stimulate mammary fibroblasts to promote mammary carcinoma cell invasion. Plos One. 8: e67533. PMID 23840733 DOI: 10.1371/Journal.Pone.0067533  0.438
2013 Miyabayashi K, Ijichi H, Mohri D, Tada M, Yamamoto K, Asaoka Y, Ikenoue T, Tateishi K, Nakai Y, Isayama H, Morishita Y, Omata M, Moses HL, Koike K. Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. Cancer Research. 73: 2221-34. PMID 23378339 DOI: 10.1158/0008-5472.Can-12-1453  0.372
2013 Takahashi R, Hirata Y, Sakitani K, Nakata W, Kinoshita H, Hayakawa Y, Nakagawa H, Sakamoto K, Hikiba Y, Ijichi H, Moses HL, Maeda S, Koike K. Therapeutic effect of c-Jun N-terminal kinase inhibition on pancreatic cancer. Cancer Science. 104: 337-44. PMID 23237571 DOI: 10.1111/Cas.12080  0.361
2013 Tada M, Ijichi H, Miyabayashi K, Asaoka Y, Mohri D, Ikenoue T, Mikata R, Ishihara T, Kanai F, Omata M, Moses HL, Yokosuka O. Abstract A69: The novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment. Cancer Research. 73. DOI: 10.1158/1538-7445.Tumimm2012-A69  0.374
2013 Owens P, Pickup MW, Gorska AE, Novitskiy SV, Hong CC, Moses HL. Abstract A56: Bone morphogenetic protein antagonist DMH1 inhibits metastasis in a mouse model of breast cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A56  0.451
2013 Pickup MW, Owens P, Gorska A, Chytil A, Weaver V, Moses H. Abstract A16: Stromal LOX promotes TGFβR2 null breast cancer metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A16  0.49
2013 Owens P, Bobbitt CR, Pickup MW, Gorska AE, Novitskiy SV, Moses HL. Abstract 5005: Deletion of bone morphogenetic protein receptor 1A impairs mammary gland development and tumor formation. Cancer Research. 73: 5005-5005. DOI: 10.1158/1538-7445.Am2013-5005  0.453
2013 Jovanovic B, Chen SX, Lehmann BD, Johnson KN, Sanchez V, Kuba MG, Sanders ME, Mayer IA, Moses HL, Pietenpol JA. Abstract 4698: Gene expression profiles of triple negative breast cancer epithelial and stromal cells are predictive of treatment response. Cancer Research. 73: 4698-4698. DOI: 10.1158/1538-7445.Am2013-4698  0.305
2013 Shaw AK, Novitskiy S, Coussens LM, Moses HL. Abstract 2301: Myeloid cells promote fibroblast invasion and lead mammary adenocarcinoma cell invasion. Cancer Research. 73: 2301-2301. DOI: 10.1158/1538-7445.Am2013-2301  0.448
2012 Novitskiy SV, Moses HL. Turn off the IDO: will clinical trials be successful? Cancer Discovery. 2: 673-5. PMID 22886661 DOI: 10.1158/2159-8290.Cd-12-0311  0.327
2012 Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Pickup MW, Gorska AE, Zijlstra A, Moses HL. Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk. Breast Cancer Research : Bcr. 14: R98. PMID 22748014 DOI: 10.1186/Bcr3217  0.832
2012 Novitskiy SV, Pickup MW, Chytil A, Polosukhina D, Owens P, Moses HL. Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties. Journal of Leukocyte Biology. 92: 641-51. PMID 22685318 DOI: 10.1189/Jlb.1211639  0.42
2012 Ma X, Beeghly-Fadiel A, Lu W, Shi J, Xiang YB, Cai Q, Shen H, Shen CY, Ren Z, Matsuo K, Khoo US, Iwasaki M, Long J, Zhang B, Ji BT, ... ... Moses HL, et al. Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 1176-84. PMID 22539603 DOI: 10.1158/1055-9965.Epi-12-0118  0.362
2012 Kurley SJ, Bierie B, Carnahan RH, Lobdell NA, Davis MA, Hofmann I, Moses HL, Muller WJ, Reynolds AB. p120-catenin is essential for terminal end bud function and mammary morphogenesis. Development (Cambridge, England). 139: 1754-64. PMID 22461563 DOI: 10.1242/Dev.072769  0.684
2012 Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL. Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators. Proceedings of the National Academy of Sciences of the United States of America. 109: 2814-9. PMID 21576484 DOI: 10.1073/Pnas.1101139108  0.461
2012 Steiner MS, Satterwhite DJ, Moses HL. Molecular insights into altered cell cycle regulation and genitourinary malignancy. Urologic Oncology. 1: 3-17. PMID 21224085 DOI: 10.1016/1078-1439(95)00005-3  0.441
2012 Miyabayashi K, Isayama H, Omata M, Moses HL, Koike K, Ijichi H, Mohri D, Tada M, Yamamoto K, Asaoka Y, Ikenoue T, Tateishi K, Nakai Y. Abstract B27: Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced mitogen-activated protein kinase signal. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-B27  0.407
2012 Tada M, Omata M, Moses HL, Yokosuka O, Ijichi H, Miyabayashi K, Asaoka Y, Mohri D, Ikenoue T, Mikata R, Ishihara T, Kanai F. Abstract A85: The exploration of novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A85  0.363
2012 Laklai H, Kalluri R, Moses H, Weaver V, Ijichi H, Lakins J, Miroshnikova Y, Acerbi I, Lopez J, Kassianidou E, Gorska A, Novitskiy S. Abstract A47: Reciprocal dialogue between cellular and extracellular matrix tension and tissue inflammation in pancreatic tumor progression. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A47  0.406
2012 Shaw AK, Novitskiy S, Moses HL. Abstract LB-495: Myeloid-derived suppressor cells promote cancer-associated fibroblast migration and carcinoma cell invasion Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-495  0.431
2012 Miyabayashi K, Ijichi H, Mohri D, Tada M, Yamamoto K, Asaoka Y, Ikenoue T, Nakai Y, Isayama H, Omata M, Moses H, Koike K. Abstract 851: Epidermal growth factor receptor inhibitor erlotinib prolongs survival inKras-mutant pancreatic ductal adenocarcinoma by inhibiting gemcitabine-induced mitogen activated protein kinase signaling activation Cancer Research. 72: 851-851. DOI: 10.1158/1538-7445.Am2012-851  0.479
2012 Tada M, Ijichi H, Miyabayashi K, Asaoka Y, Mohri D, Ikenoue T, Mikata R, Tawada K, Ishihara T, Kanai F, Imazeki F, Omata M, Moses HL, Yokosuka O. Abstract 4383: Targeting tumor microenvironment with gemcitabine is useful for the treatment of pancreatic ductal adenocarcinoma Cancer Research. 72: 4383-4383. DOI: 10.1158/1538-7445.Am2012-4383  0.369
2012 Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Gorska A, Pickup MW, Zijlstra A, Moses HL. Abstract 4306: Lack of TGF-β signaling induces a switch from single to collective cell migration in vivo Cancer Research. 72: 4306-4306. DOI: 10.1158/1538-7445.Am2012-4306  0.523
2012 Pickup M, Chytil A, Gorska A, Aakre M, Weaver V, Moses H. Abstract 2456: TGF-Beta regulates tumor ECM remodeling and progression to metastasis Cancer Research. 72: 2456-2456. DOI: 10.1158/1538-7445.Am2012-2456  0.51
2012 Schaffer MW, Smith JC, Seeley EH, Norris JL, Ballard BR, Schey KL, Moses HL, Caprioli RM, Adunyah SE, M'Koma AE. Abstract 2058: Colorectal cancer in the setting of inflammatory bowel disease: role of hemoglobin Cancer Research. 72: 2058-2058. DOI: 10.1158/1538-7445.Am2012-2058  0.319
2012 Owens P, Polikowsky H, Pickup MW, Matise LA, Gorska AE, Shaw AK, Novitskiy SV, Aakre ME, Hong CC, Moses HL. Abstract 1500: Bone morphogenetic proteins stimulate mammary fibroblasts to promote mammary tumorigenesis Cancer Research. 72: 1500-1500. DOI: 10.1158/1538-7445.Am2012-1500  0.811
2011 Novitskiy SV, Pickup MW, Gorska AE, Owens P, Chytil A, Aakre M, Wu H, Shyr Y, Moses HL. TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. Cancer Discovery. 1: 430-41. PMID 22408746 DOI: 10.1158/2159-8290.Cd-11-0100  0.385
2011 Clark PE, Polosukhina D, Love H, Correa H, Coffin C, Perlman EJ, de Caestecker M, Moses HL, Zent R. β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors. The American Journal of Pathology. 179: 3045-55. PMID 21983638 DOI: 10.1016/J.Ajpath.2011.08.006  0.426
2011 Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, ... Moses HL, et al. Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma. The Journal of Clinical Investigation. 121: 4106-17. PMID 21926469 DOI: 10.1172/Jci42754  0.746
2011 Fang WB, Jokar I, Chytil A, Moses HL, Abel T, Cheng N. Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression. Clinical & Experimental Metastasis. 28: 351-66. PMID 21374085 DOI: 10.1007/S10585-011-9373-0  0.503
2011 Johnson MD, Shaw AK, O'Connell MJ, Sim FJ, Moses HL. Analysis of transforming growth factor β receptor expression and signaling in higher grade meningiomas. Journal of Neuro-Oncology. 103: 277-85. PMID 20853018 DOI: 10.1007/S11060-010-0399-Y  0.476
2011 Moses H, Barcellos-Hoff MH. TGF-beta biology in mammary development and breast cancer. Cold Spring Harbor Perspectives in Biology. 3: a003277. PMID 20810549 DOI: 10.1101/Cshperspect.A003277  0.477
2011 Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre M, Moses HL. Abstract 922: Disruption of bone morphogenetic protein receptor 2 accelerates mammary carcinoma metastasis to the lung Cancer Research. 71: 922-922. DOI: 10.1158/1538-7445.Am2011-922  0.474
2011 Ijichi H, Tada M, Miyabayashi K, Mohri D, Asaoka Y, Tateishi K, Ikenoue T, Omata M, Koike K, Moses HL. Abstract 544: Blockade of CXC chemokines/CXCR2 axis in the tumor microenvironment as a potent therapeutic strategy for pancreatic ductal adenocarcinoma Cancer Research. 71: 544-544. DOI: 10.1158/1538-7445.Am2011-544  0.482
2011 Tada M, Ijichi H, Miyabayashi K, Mohri D, Asaoka Y, Ikenoue T, Tateishi K, Mikata R, Ishihara T, Kanai F, Imazeki F, Moses HL, Omata M, Yokosuka O. Abstract 3292: The exploration of novel strategy for treatment of pancreactic cancer using genetically engineered mice Cancer Research. 71: 3292-3292. DOI: 10.1158/1538-7445.Am2011-3292  0.348
2011 Novitskiy S, Gorska A, Pickup M, Chytil A, Aakre M, Moses HL. Abstract 2845: Dominant-negative TGFβRII (DNIIR) in c-neu-induced mammary carcinoma cells increases metastasis by disturbing vasculogenesis and pericyte balance Cancer Research. 71: 2845-2845. DOI: 10.1158/1538-7445.Am2011-2845  0.484
2011 Miyabayashi K, Ijichi H, Mohri D, Tada M, Asaoka Y, Ikenoue T, Omata M, Moses HL, Koike K. Abstract 2381: Preclinical molecular targeting therapy of pancreatic cancer using a genetically engineered mouse model Cancer Research. 71: 2381-2381. DOI: 10.1158/1538-7445.Am2011-2381  0.324
2010 Xu BJ, Yan W, Jovanovic B, Shaw AK, An QA, Eng J, Chytil A, Link AJ, Moses HL. Microdialysis combined with proteomics for protein identification in breast tumor microenvironment in vivo. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. 4: 61-71. PMID 21505562 DOI: 10.1007/S12307-010-0046-3  0.381
2010 Clark PE, Polosukhina DA, Gyabaah K, Moses HL, Thorburn A, Zent R. TRAIL and interferon-alpha act synergistically to induce renal cell carcinoma apoptosis. The Journal of Urology. 184: 1166-74. PMID 20663526 DOI: 10.1016/J.Juro.2010.04.064  0.317
2010 Yan HH, Pickup M, Pang Y, Gorska AE, Li Z, Chytil A, Geng Y, Gray JW, Moses HL, Yang L. Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Research. 70: 6139-49. PMID 20631080 DOI: 10.1158/0008-5472.Can-10-0706  0.351
2010 Gewin L, Bulus N, Mernaugh G, Moeckel G, Harris RC, Moses HL, Pozzi A, Zent R. TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. Journal of the American Society of Nephrology : Jasn. 21: 1334-43. PMID 20576806 DOI: 10.1681/Asn.2010020147  0.493
2010 Yang L, Pang Y, Moses HL. TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression. Trends in Immunology. 31: 220-7. PMID 20538542 DOI: 10.1016/J.It.2010.04.002  0.536
2010 Xu BJ, Yan W, Jovanovic B, An AQ, Cheng N, Aakre ME, Yi Y, Eng J, Link AJ, Moses HL. Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts. Proteomics. 10: 2458-70. PMID 20405477 DOI: 10.1002/Pmic.200900701  0.58
2010 Bierie B, Moses HL. Transforming growth factor beta (TGF-beta) and inflammation in cancer. Cytokine & Growth Factor Reviews. 21: 49-59. PMID 20018551 DOI: 10.1016/J.Cytogfr.2009.11.008  0.795
2010 Owens P, Gorska AE, Aakre ME, Moses HL. Abstract 3840: Bone morphogenetic proteins require the type II TGFβ receptor for growth arrest in mammary tumor cells Cancer Research. 70: 3840-3840. DOI: 10.1158/1538-7445.Am10-3840  0.506
2010 Ijichi H, Tada M, Miyabayashi K, Imai M, Mohri D, Asaoka Y, Ikenoue T, Tateishi K, Omata M, Moses HL. Abstract 2259: Blockade of CXC chemokines/CXCR2 axis inhibits pancreatic ductal adenocarcinoma progression through anti-angiogenesis Cancer Research. 70: 2259-2259. DOI: 10.1158/1538-7445.Am10-2259  0.413
2009 Matise LA, Pickup MW, Moses HL. TGF-beta helps cells fly solo. Nature Cell Biology. 11: 1281-4. PMID 19838176 DOI: 10.1038/Ncb1109-1281  0.822
2009 Bierie B, Moses HL. Gain or loss of TGFbeta signaling in mammary carcinoma cells can promote metastasis. Cell Cycle (Georgetown, Tex.). 8: 3319-27. PMID 19806012 DOI: 10.4161/Cc.8.20.9727  0.75
2009 Bierie B, Chung CH, Parker JS, Stover DG, Cheng N, Chytil A, Aakre M, Shyr Y, Moses HL. Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer. The Journal of Clinical Investigation. 119: 1571-82. PMID 19451693 DOI: 10.1172/Jci37480  0.779
2009 Abel TW, Clark C, Bierie B, Chytil A, Aakre M, Gorska A, Moses HL. GFAP-Cre-mediated activation of oncogenic K-ras results in expansion of the subventricular zone and infiltrating glioma. Molecular Cancer Research : McR. 7: 645-53. PMID 19435821 DOI: 10.1158/1541-7786.Mcr-08-0477  0.715
2009 Bierie B, Gorska AE, Stover DG, Moses HL. TGF-beta promotes cell death and suppresses lactation during the second stage of mammary involution. Journal of Cellular Physiology. 219: 57-68. PMID 19086032 DOI: 10.1002/Jcp.21646  0.772
2008 Yang L, Moses HL. Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer? Cancer Research. 68: 9107-11. PMID 19010878 DOI: 10.1158/0008-5472.Can-08-2556  0.489
2008 Cheng N, Chytil A, Shyr Y, Joly A, Moses HL. Transforming growth factor-beta signaling-deficient fibroblasts enhance hepatocyte growth factor signaling in mammary carcinoma cells to promote scattering and invasion. Molecular Cancer Research : McR. 6: 1521-33. PMID 18922968 DOI: 10.1158/1541-7786.Mcr-07-2203  0.568
2008 Brown KA, Ham AJ, Clark CN, Meller N, Law BK, Chytil A, Cheng N, Pietenpol JA, Moses HL. Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1. Journal of Cellular Biochemistry. 105: 596-611. PMID 18729074 DOI: 10.1002/Jcb.21860  0.536
2008 Erdogan M, Pozzi A, Bhowmick N, Moses HL, Zent R. Transforming growth factor-beta (TGF-beta) and TGF-beta-associated kinase 1 are required for R-Ras-mediated transformation of mammary epithelial cells. Cancer Research. 68: 6224-31. PMID 18676846 DOI: 10.1158/0008-5472.Can-08-0513  0.804
2008 Bierie B, Stover DG, Abel TW, Chytil A, Gorska AE, Aakre M, Forrester E, Yang L, Wagner KU, Moses HL. Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. Cancer Research. 68: 1809-19. PMID 18339861 DOI: 10.1158/0008-5472.Can-07-5597  0.84
2008 Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, Carbone DP, Matrisian LM, Richmond A, Lin PC, Moses HL. Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell. 13: 23-35. PMID 18167337 DOI: 10.1016/J.Ccr.2007.12.004  0.532
2008 Bierie B, Moses HL. 30 TGF-β and the Tumor Microenvironment Cold Spring Harbor Monograph Archive. 50: 965-987. DOI: 10.1101/087969752.50.965  0.741
2008 Moses HL, Roberts AB. 1 The Discovery of TGF-β: A Historical Perspective Cold Spring Harbor Monograph Archive. 50: 1-28. DOI: 10.1101/087969752.50.1  0.416
2008 Ijichi H, Omata M, Wright CV, Moses HL. 147 Aggressive Pancreatic Ductal Adenocarcinoma in Mice Releases Secreted Factors Into the Tumor Microenvironment to Enhance Tumor Progression Gastroenterology. 134: A-26. DOI: 10.1016/S0016-5085(08)60129-8  0.356
2007 Erdogan M, Pozzi A, Bhowmick N, Moses HL, Zent R. Signaling pathways regulating TC21-induced tumorigenesis. The Journal of Biological Chemistry. 282: 27713-20. PMID 17656362 DOI: 10.1074/Jbc.M703037200  0.824
2007 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL. TGF-beta signaling is essential for joint morphogenesis. The Journal of Cell Biology. 177: 1105-17. PMID 17576802 DOI: 10.1083/Jcb.200611031  0.499
2007 Hoshino A, Yee CJ, Campbell M, Woltjer RL, Townsend RL, van der Meer R, Shyr Y, Holt JT, Moses HL, Jensen RA. Effects of BRCA1 transgene expression on murine mammary gland development and mutagen-induced mammary neoplasia. International Journal of Biological Sciences. 3: 281-91. PMID 17505536 DOI: 10.7150/Ijbs.3.281  0.344
2007 Bonine-Summers AR, Aakre ME, Brown KA, Arteaga CL, Pietenpol JA, Moses HL, Cheng N. Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells. Cancer Biology & Therapy. 6: 561-70. PMID 17495520 DOI: 10.4161/Cbt.6.4.3851  0.779
2007 Cheng N, Chytil A, Shyr Y, Joly A, Moses HL. Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis. Cancer Research. 67: 4869-77. PMID 17495323 DOI: 10.1158/0008-5472.Can-06-3381  0.591
2007 Stover DG, Bierie B, Moses HL. A delicate balance: TGF-beta and the tumor microenvironment. Journal of Cellular Biochemistry. 101: 851-61. PMID 17486574 DOI: 10.1002/Jcb.21149  0.805
2007 Biswas S, Guix M, Rinehart C, Dugger TC, Chytil A, Moses HL, Freeman ML, Arteaga CL. Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. The Journal of Clinical Investigation. 117: 1305-13. PMID 17415413 DOI: 10.1172/Jci30740  0.544
2007 Brown KA, Pietenpol JA, Moses HL. A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling. Journal of Cellular Biochemistry. 101: 9-33. PMID 17340614 DOI: 10.1002/Jcb.21255  0.555
2007 Labbé E, Lock L, Letamendia A, Gorska AE, Gryfe R, Gallinger S, Moses HL, Attisano L. Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis. Cancer Research. 67: 75-84. PMID 17210685 DOI: 10.1158/0008-5472.Can-06-2559  0.56
2006 Ijichi H, Chytil A, Gorska AE, Aakre ME, Fujitani Y, Fujitani S, Wright CV, Moses HL. Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. Genes & Development. 20: 3147-60. PMID 17114585 DOI: 10.1101/Gad.1475506  0.526
2006 Jiao K, Langworthy M, Batts L, Brown CB, Moses HL, Baldwin HS. Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development. Development (Cambridge, England). 133: 4585-93. PMID 17050629 DOI: 10.1242/Dev.02597  0.365
2006 Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, Sozmen EG, Madison BB, Pozzi A, Moon RT, Moses HL, Grady WM. Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Research. 66: 9837-44. PMID 17047044 DOI: 10.1158/0008-5472.Can-06-0890  0.52
2006 Bierie B, Moses HL. Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nature Reviews. Cancer. 6: 506-20. PMID 16794634 DOI: 10.1038/Nrc1926  0.739
2006 Halder SK, Anumanthan G, Maddula R, Mann J, Chytil A, Gonzalez AL, Washington MK, Moses HL, Beauchamp RD, Datta PK. Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis. Cancer Research. 66: 6156-66. PMID 16778189 DOI: 10.1158/0008-5472.Can-05-3261  0.583
2006 Longobardi L, O'Rear L, Aakula S, Johnstone B, Shimer K, Chytil A, Horton WA, Moses HL, Spagnoli A. Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 626-36. PMID 16598383 DOI: 10.1359/Jbmr.051213  0.494
2006 Bierie B, Moses HL. TGF-beta and cancer. Cytokine & Growth Factor Reviews. 17: 29-40. PMID 16289860 DOI: 10.1016/J.Cytogfr.2005.09.006  0.792
2005 Bierie B, Moses HL. Under pressure: stromal fibroblasts change their ways. Cell. 123: 985-7. PMID 16360028 DOI: 10.1016/J.Cell.2005.11.029  0.726
2005 Xie L, Xu BJ, Gorska AE, Shyr Y, Schwartz SA, Cheng N, Levy S, Bierie B, Caprioli RM, Moses HL. Genomic and proteomic analysis of mammary tumors arising in transgenic mice. Journal of Proteome Research. 4: 2088-98. PMID 16335954 DOI: 10.1021/Pr050214L  0.786
2005 Ewan KB, Oketch-Rabah HA, Ravani SA, Shyamala G, Moses HL, Barcellos-Hoff MH. Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice. The American Journal of Pathology. 167: 409-17. PMID 16049327 DOI: 10.1016/S0002-9440(10)62985-9  0.408
2005 O'Rear L, Longobardi L, Torello M, Law BK, Moses HL, Chiarelli F, Spagnoli A. Signaling cross-talk between IGF-binding protein-3 and transforming growth factor-(beta) in mesenchymal chondroprogenitor cell growth. Journal of Molecular Endocrinology. 34: 723-37. PMID 15956343 DOI: 10.1677/Jme.1.01746  0.547
2005 Cheng N, Bhowmick NA, Chytil A, Gorksa AE, Brown KA, Muraoka R, Arteaga CL, Neilson EG, Hayward SW, Moses HL. Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks. Oncogene. 24: 5053-68. PMID 15856015 DOI: 10.1038/Sj.Onc.1208685  0.739
2005 Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL. Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. Cancer Research. 65: 2296-302. PMID 15781643 DOI: 10.1158/0008-5472.Can-04-3272  0.844
2005 Desgrosellier JS, Mundell NA, McDonnell MA, Moses HL, Barnett JV. Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. Developmental Biology. 280: 201-10. PMID 15766759 DOI: 10.1016/J.Ydbio.2004.12.037  0.462
2005 Romero-Gallo J, Sozmen EG, Chytil A, Russell WE, Whitehead R, Parks WT, Holdren MS, Her MF, Gautam S, Magnuson M, Moses HL, Grady WM. Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy. Oncogene. 24: 3028-41. PMID 15735717 DOI: 10.1038/Sj.Onc.1208475  0.527
2005 Bhowmick NA, Moses HL. Tumor-stroma interactions. Current Opinion in Genetics & Development. 15: 97-101. PMID 15661539 DOI: 10.1016/J.Gde.2004.12.003  0.65
2005 Moses H, Cheng N, Chytil A, Gorska A, Aakre M, Forrester E, Neilson E, Bhowmick N. Stromal and epithelial TGF-β signaling in mammary tumorigenesis Breast Cancer Research. 7. DOI: 10.1186/Bcr1045  0.836
2004 Beebe D, Garcia C, Wang X, Rajagopal R, Feldmeier M, Kim J, Chytil A, Moses H, Ashery-Padan R, Rauchman M. Contributions by members of the TGFbeta superfamily to lens development The International Journal of Developmental Biology. 48: 845-856. PMID 15558476 DOI: 10.1387/Ijdb.041869Db  0.366
2004 Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature. 432: 332-7. PMID 15549095 DOI: 10.1038/Nature03096  0.6
2004 Xie L, Law BK, Chytil AM, Brown KA, Aakre ME, Moses HL. Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia (New York, N.Y.). 6: 603-10. PMID 15548370 DOI: 10.1593/Neo.04241  0.545
2004 Baffi MO, Slattery E, Sohn P, Moses HL, Chytil A, Serra R. Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones. Developmental Biology. 276: 124-42. PMID 15531369 DOI: 10.1016/J.Ydbio.2004.08.027  0.493
2004 Biswas S, Chytil A, Washington K, Romero-Gallo J, Gorska AE, Wirth PS, Gautam S, Moses HL, Grady WM. Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer. Cancer Research. 64: 4687-92. PMID 15256431 DOI: 10.1158/0008-5472.Can-03-3255  0.528
2004 Brown KA, Aakre ME, Gorska AE, Price JO, Eltom SE, Pietenpol JA, Moses HL. Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro. Breast Cancer Research : Bcr. 6: R215-31. PMID 15084245 DOI: 10.1186/Bcr778  0.537
2004 Bhowmick NA, Chytil A, Plieth D, Gorska AE, Dumont N, Shappell S, Washington MK, Neilson EG, Moses HL. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science (New York, N.Y.). 303: 848-51. PMID 14764882 DOI: 10.1126/Science.1090922  0.726
2004 Sharif‐Afshar A, Gorska AE, Neilson EG, Davidson JM, Moses HL, Bhowmick NA. 071 TGF?�?Mediated Paracrine Regulation of Keratinocyte Wound Closure Wound Repair and Regeneration. 12: A20-A20. DOI: 10.1111/J.1067-1927.2004.0Abstractbr.X  0.632
2004 Bhowmick NA, Moses HL. 413: The Conditional Knock-Out of Transforming Growth Factor-Beta Signaling in the Prostate Stroma Results in Prostate Intraepithelial Neoplasia Journal of Urology. 171: 109-109. DOI: 10.1016/S0022-5347(18)37675-4  0.61
2003 Bhowmick NA, Ghiassi M, Aakre M, Brown K, Singh V, Moses HL. TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest. Proceedings of the National Academy of Sciences of the United States of America. 100: 15548-53. PMID 14657354 DOI: 10.1073/Pnas.2536483100  0.717
2003 Muraoka RS, Koh Y, Roebuck LR, Sanders ME, Brantley-Sieders D, Gorska AE, Moses HL, Arteaga CL. Increased malignancy of Neu-induced mammary tumors overexpressing active transforming growth factor beta1. Molecular and Cellular Biology. 23: 8691-703. PMID 14612410 DOI: 10.1128/Mcb.23.23.8691-8703.2003  0.563
2003 Xie L, Law BK, Aakre ME, Edgerton M, Shyr Y, Bhowmick NA, Moses HL. Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Research : Bcr. 5: R187-98. PMID 14580254 DOI: 10.1186/Bcr640  0.713
2003 Gorska AE, Jensen RA, Shyr Y, Aakre ME, Bhowmick NA, Moses HL. Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-beta receptor exhibit impaired mammary development and enhanced mammary tumor formation. The American Journal of Pathology. 163: 1539-49. PMID 14507660 DOI: 10.1016/S0002-9440(10)63510-9  0.687
2003 Ito Y, Yeo JY, Chytil A, Han J, Bringas P, Nakajima A, Shuler CF, Moses HL, Chai Y. Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development (Cambridge, England). 130: 5269-80. PMID 12975342 DOI: 10.1242/Dev.00708  0.357
2003 Tu WH, Thomas TZ, Masumori N, Bhowmick NA, Gorska AE, Shyr Y, Kasper S, Case T, Roberts RL, Shappell SB, Moses HL, Matusik RJ. The loss of TGF-beta signaling promotes prostate cancer metastasis. Neoplasia (New York, N.Y.). 5: 267-77. PMID 12869309 DOI: 10.1016/S1476-5586(03)80058-1  0.682
2003 ROMEROGALLO J, CHYTIL A, RUSSELL W, MAGNUSON M, GAUTAM S, MOSES H, GRADY W. 848 TGF-β signal pathway activation regulates restoration of quiescence in the regenerating liver and of the liver mass: body weight ratio after partial hepatectomy Hepatology. 38: 570-570. DOI: 10.1016/S0270-9139(03)80890-X  0.33
2002 Glaser KB, Li J, Aakre ME, Morgan DW, Sheppard G, Stewart KD, Pollock J, Lee P, O'Connor CZ, Anderson SN, Mussatto DJ, Wegner CW, Moses HL. Transforming growth factor beta mimetics: discovery of 7-[4-(4-cyanophenyl)phenoxy]-heptanohydroxamic acid, a biaryl hydroxamate inhibitor of histone deacetylase. Molecular Cancer Therapeutics. 1: 759-68. PMID 12492108  0.426
2002 Law BK, Chytil A, Dumont N, Hamilton EG, Waltner-Law ME, Aakre ME, Covington C, Moses HL. Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. Molecular and Cellular Biology. 22: 8184-98. PMID 12417722 DOI: 10.1128/Mcb.22.23.8184-8198.2002  0.548
2002 Chytil A, Magnuson MA, Wright CV, Moses HL. Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis (New York, N.Y. : 2000). 32: 73-5. PMID 11857781 DOI: 10.1002/Gene.10046  0.421
2001 Entingh AJ, Law BK, Moses HL. Induction of the C/EBP Homologous Protein (CHOP) by Amino Acid Deprivation Requires Insulin-Like Growth Factor I, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Signaling* * This work was supported by NIH Grants CA-42572 and CA-85492. Sequencing was carried out by the DNA Sequencing Shared Resource (Grant P30-CA-68485). Data presentation was performed in part through the use of the Vanderbilt University Medical Center Cell Imaging Resource (Grants CA-68485 and DK-20593). Endocrinology. 142: 221-228. PMID 28201340 DOI: 10.1210/endo.142.1.7906  0.755
2001 Bragg AD, Moses HL, Serra R. Signaling to the epithelium is not sufficient to mediate all of the effects of transforming growth factor beta and bone morphogenetic protein 4 on murine embryonic lung development. Mechanisms of Development. 109: 13-26. PMID 11677049 DOI: 10.1016/S0925-4773(01)00508-1  0.814
2001 Bhowmick NA, Zent R, Ghiassi M, McDonnell M, Moses HL. Integrin β1 Signaling is Necessary for Transforming Growtn Factor-β Activation of p38MAPK and Epithelial Plasticity Journal of Biological Chemistry. 276: 46707-46713. PMID 11590169 DOI: 10.1074/Jbc.M106176200  0.649
2001 Satterwhite DJ, White RL, Aakre ME, Moses HL. TGF-beta1 regulates the expression of multiple max-interacting transcription factors in Balb/MK cells: implications for understanding the mechanism of action of TGF-beta1. Pediatric Research. 50: 67-75. PMID 11420421 DOI: 10.1203/00006450-200107000-00014  0.526
2001 McDonnell MA, Law BK, Serra R, Moses HL. Antagonistic effects of TGFbeta1 and BMP-6 on skin keratinocyte differentiation. Experimental Cell Research. 263: 265-73. PMID 11161725 DOI: 10.1006/Excr.2000.5117  0.415
2001 Bhowmick NA, Ghiassi M, Bakin A, Aakre M, Lundquist CA, Engel ME, Arteaga CL, Moses HL. Transforming growth factor-β1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism Molecular Biology of the Cell. 12: 27-36. PMID 11160820 DOI: 10.1091/Mbc.12.1.27  0.674
2001 Entingh AJ, Law BK, Moses HL. Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling. Endocrinology. 142: 221-8. PMID 11145585 DOI: 10.1210/Endo.142.1.7906  0.774
2000 Datta PK, Blake MC, Moses HL. Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1. The Journal of Biological Chemistry. 275: 40014-9. PMID 11054406 DOI: 10.1074/Jbc.C000508200  0.42
2000 Law BK, Waltner-Law ME, Entingh AJ, Chytil A, Aakre ME, Nørgaard P, Moses HL. Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen. The Journal of Biological Chemistry. 275: 38261-7. PMID 10993886 DOI: 10.1074/Jbc.M005545200  0.776
2000 Bakin AV, Tomlinson AK, Bhowmick NA, Moses HL, Arteaga CL. Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration. The Journal of Biological Chemistry. 275: 36803-10. PMID 10969078 DOI: 10.1074/Jbc.M005912200  0.681
2000 Arteaga CL, Moses HL. TGF-beta in mammary development and neoplasia. Journal of Mammary Gland Biology and Neoplasia. 1: 327-9. PMID 10887506 DOI: 10.1007/Bf02017388  0.475
2000 Datta PK, Moses HL. STRAP and Smad7 synergize in the inhibition of transforming growth factor beta signaling. Molecular and Cellular Biology. 20: 3157-67. PMID 10757800 DOI: 10.1128/Mcb.20.9.3157-3167.2000  0.478
2000 Law BK, Norgaard P, Moses HL. Farnesyltransferase inhibitor induces rapid growth arrest and blocks p70s6k activation by multiple stimuli. The Journal of Biological Chemistry. 275: 10796-801. PMID 10753872 DOI: 10.1074/Jbc.275.15.10796  0.344
1999 Saha D, Datta PK, Sheng H, Morrow JD, Wada M, Moses HL, Beauchamp RD. Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. Neoplasia (New York, N.Y.). 1: 508-17. PMID 10935498 DOI: 10.1038/Sj.Neo.7900051  0.498
1999 Engel ME, McDonnell MA, Law BK, Moses HL. Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription. The Journal of Biological Chemistry. 274: 37413-20. PMID 10601313 DOI: 10.1074/Jbc.274.52.37413  0.519
1999 Moses H, Sriram S. Interferon beta and the cytokine trail: where are we going? Neurology. 52: 1729-1729. PMID 10371513 DOI: 10.1212/Wnl.52.9.1729  0.308
1999 Joseph H, Gorska AE, Sohn P, Moses HL, Serra R. Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching. Molecular Biology of the Cell. 10: 1221-34. PMID 10198068 DOI: 10.1091/Mbc.10.4.1221  0.529
1999 Hougaard S, Nørgaard P, Abrahamsen N, Moses HL, Spang-Thomsen M, Skovgaard Poulsen H. Inactivation of the transforming growth factor beta type II receptor in human small cell lung cancer cell lines. British Journal of Cancer. 79: 1005-11. PMID 10098728 DOI: 10.1038/Sj.Bjc.6690161  0.423
1999 Datta PK, Chytil A, Gorska AE, Moses HL. Identification of STRAP, a novel WD domain protein in transforming growth factor-beta signaling. The Journal of Biological Chemistry. 273: 34671-4. PMID 9856985 DOI: 10.1074/Jbc.273.52.34671  0.518
1998 Engel ME, Datta PK, Moses HL. Signal transduction by transforming growth factor-β: A cooperative paradigm with extensive negative regulation. Journal of Cellular Biochemistry. 72: 111-122. PMID 29345828 DOI: 10.1002/(Sici)1097-4644(1998)72:30/31+<111::Aid-Jcb15>3.0.Co;2-5  0.464
1998 Sarkar DK, Pastorcic M, De A, Engel M, Moses H, Ghasemzadeh MB. Role of Transforming Growth Factor (TGF)-β Type I and TGF-β Type II Receptors in the TGF-β1-Regulated Gene Expression in Pituitary Prolactin-Secreting Lactotropes. Endocrinology. 139: 3620-3628. PMID 28200627 DOI: 10.1210/endo.139.8.6135  0.304
1998 Alexandrow MG, Moses HL. c-Myc-enhanced S phase entry in keratinocytes is associated with positive and negative effects on cyclin-dependent kinases Journal of Cellular Biochemistry. 70: 528-542. PMID 9712150 DOI: 10.1002/(Sici)1097-4644(19980915)70:4<528::Aid-Jcb9>3.0.Co;2-L  0.339
1998 Sarkar DK, Pastorcic M, De A, Engel M, Moses H, Ghasemzadeh MB. Role of transforming growth factor (TGF)-β type I and TGF-β type II receptors in the TGF-β1-regulated gene expression in pituitary prolactin- secreting lactotropes Endocrinology. 139: 3620-3628. PMID 9681516 DOI: 10.1210/Endo.139.8.6135  0.52
1998 Engel ME, Datta PK, Moses HL. RhoB is stabilized by transforming growth factor beta and antagonizes transcriptional activation. The Journal of Biological Chemistry. 273: 9921-6. PMID 9545335 DOI: 10.1074/Jbc.273.16.9921  0.516
1997 Burger MM, Moses HL. UICC Study Group on Basic and Clinical Cancer Research: mechanisms of growth factor and hormone insensitivity. International Journal of Cancer. Journal International Du Cancer. 73: 461-3. PMID 9389556 DOI: 10.1002/(Sici)1097-0215(19971114)73:4<461::Aid-Ijc1>3.0.Co;2-Y  0.308
1997 Serra R, Johnson M, Filvaroff EH, LaBorde J, Sheehan DM, Derynck R, Moses HL. Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. The Journal of Cell Biology. 139: 541-52. PMID 9334355 DOI: 10.1083/Jcb.139.2.541  0.462
1997 Alexandrow MG, Moses HL. Kips off to myc: Implications for TGFβ signaling Journal of Cellular Biochemistry. 66: 427-432. PMID 9282320 DOI: 10.1002/(Sici)1097-4644(19970915)66:4<427::Aid-Jcb1>3.0.Co;2-N  0.465
1997 Mason RJ, Williams MC, Moses HL, Mohla S, Berberich MA. Stem cells in lung development, disease, and therapy. American Journal of Respiratory Cell and Molecular Biology. 16: 355-63. PMID 9115744 DOI: 10.1165/Ajrcmb.16.4.9115744  0.303
1997 Moses HL, Serra R. Regulation of differentiation by TGF-beta. Current Opinion in Genetics & Development. 6: 581-6. PMID 8939725 DOI: 10.1016/S0959-437X(96)80087-6  0.512
1996 Holt JT, Arteaga CB, Robertson D, Moses HL. Gene therapy for the treatment of metastatic breast cancer by in vivo transduction with breast-targeted retroviral vector expressing antisense c-fos RNA. Human Gene Therapy. 7: 1367-80. PMID 8818724 DOI: 10.1089/Hum.1996.7.11-1367  0.365
1996 Okadome T, Oeda E, Saitoh M, Ichijo H, Moses HL, Miyazono K, Kawabata M. Characterization of the interaction of FKBP12 with the transforming growth factor-beta type I receptor in vivo. The Journal of Biological Chemistry. 271: 21687-90. PMID 8702959 DOI: 10.1074/Jbc.271.36.21687  0.421
1996 Serra R, Moses HL. Tumor suppressor genes in the TGF-beta signaling pathway? Nature Medicine. 2: 390-1. PMID 8597940 DOI: 10.1038/Nm0496-390  0.537
1996 Kawabata M, Imamura T, Miyazono K, Engel ME, Moses HL. Interaction of the transforming growth factor-beta type I receptor with farnesyl-protein transferase-alpha. The Journal of Biological Chemistry. 270: 29628-31. PMID 8530343 DOI: 10.1074/Jbc.270.50.29628  0.421
1995 Steiner MS, Anthony CT, Metts J, Moses HL. Prostate cancer cells lose their sensitivity to TGFβI growth inhibition with tumor progression. Urologic Oncology. 1: 252-62. PMID 21224127 DOI: 10.1016/1078-1439(96)00028-2  0.396
1995 Kawabata M, Chytil A, Moses HL. Cloning of a novel type II serine/threonine kinase receptor through interaction with the type I transforming growth factor-β receptor Journal of Biological Chemistry. 270: 5625-5630. PMID 7890683 DOI: 10.1074/Jbc.270.10.5625  0.346
1995 Pierce DF, Gorska AE, Chytil A, Meise KS, Page DL, Coffey RJ, Moses HL. Mammary tumor suppression by transforming growth factor beta 1 transgene expression. Proceedings of the National Academy of Sciences of the United States of America. 92: 4254-8. PMID 7753792 DOI: 10.1073/Pnas.92.10.4254  0.539
1995 Chen RH, Moses HL, Maruoka EM, Derynck R, Kawabata M. Phosphorylation-dependent interaction of the cytoplasmic domains of the type I and type II transforming growth factor-beta receptors. The Journal of Biological Chemistry. 270: 12235-41. PMID 7744874 DOI: 10.1074/Jbc.270.20.12235  0.423
1995 Alexandrow MG, Kawabata M, Aakre M, Moses HL. Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor β1 Proceedings of the National Academy of Sciences of the United States of America. 92: 3239-3243. PMID 7724545 DOI: 10.1073/Pnas.92.8.3239  0.414
1993 Johnson MD, Jennings MT, Gold LI, Moses HL. Transforming growth factor-beta in neural embryogenesis and neoplasia. Human Pathology. 24: 457-62. PMID 8387957 DOI: 10.1016/0046-8177(93)90156-B  0.537
1993 Dagnino L, Pietenpol JA, Yang EY, Moses HL. Transforming growth factor regulation of keratinocyte growth. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 128: 15-29. PMID 8356316 DOI: 10.1007/978-3-642-84881-0_2  0.427
1993 Pierce DF, Johnson MD, Matsui Y, Robinson SD, Gold LI, Purchio AF, Daniel CW, Hogan BL, Moses HL. Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1. Genes & Development. 7: 2308-17. PMID 8253379 DOI: 10.1101/Gad.7.12A.2308  0.53
1992 Pelton RW, Johnson MD, Perkett EA, Gold LI, Moses HL. Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 mRNA and protein in the murine lung. American Journal of Respiratory Cell and Molecular Biology. 5: 522-30. PMID 1958379 DOI: 10.1165/Ajrcmb/5.6.522  0.478
1992 Barnard JA, Polk WH, Moses HL, Coffey RJ. Production of transforming growth factor-alpha by normal rat small intestine. The American Journal of Physiology. 261: C994-1000. PMID 1767826 DOI: 10.1152/Ajpcell.1991.261.6.C994  0.389
1992 Moses HL. TGF-beta regulation of epithelial cell proliferation. Molecular Reproduction and Development. 32: 179-84. PMID 1637556 DOI: 10.1002/Mrd.1080320215  0.509
1992 Beauchamp RD, Sheng HM, Bascom CC, Miller DA, Lyons RM, Torre-Amione G, Moses HL. Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1. Endocrinology. 130: 2476-86. PMID 1374006 DOI: 10.1210/endo.130.5.1374006  0.409
1991 Pelton RW, Moses HL. The beta-type transforming growth factor. Mediators of cell regulation in the lung. The American Review of Respiratory Disease. 142: S31-5. PMID 2174660 DOI: 10.1164/Ajrccm/142.6_Pt_2.S31  0.5
1991 Moses HL, Yang EY, Pietenpol JA. Regulation of epithelial proliferation by TGF-beta. Ciba Foundation Symposium. 157: 66-74; discussion 75. PMID 2070684  0.424
1991 Pelton RW, Saxena B, Jones M, Moses HL, Gold LI. Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. The Journal of Cell Biology. 115: 1091-105. PMID 1955457 DOI: 10.1083/Jcb.115.4.1091  0.482
1991 Pietenpol JA, Münger K, Howley PM, Stein RW, Moses HL. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product. Proceedings of the National Academy of Sciences of the United States of America. 88: 10227-31. PMID 1946442 DOI: 10.1073/Pnas.88.22.10227  0.505
1991 Jennings MT, Maciunas RJ, Carver R, Bascom CC, Juneau P, Misulis K, Moses HL. TGF beta 1 and TGF beta 2 are potential growth regulators for low-grade and malignant gliomas in vitro: evidence in support of an autocrine hypothesis. International Journal of Cancer. 49: 129-39. PMID 1874566 DOI: 10.1002/Ijc.2910490124  0.509
1991 Murphy CS, Pietenpol JA, Munger K, Howley PM, Moses HL. c-myc and pRB: Role in TGF-β1 inhibition of keratinocyte proliferation Cold Spring Harbor Symposia On Quantitative Biology. 56: 129-135. PMID 1819482 DOI: 10.1101/Sqb.1991.056.01.017  0.439
1991 Schwartz HS, Butler MG, Jenkins RB, Miller DA, Moses HL. Telomeric associations and consistent growth factor overexpression detected in giant cell tumor of bone. Cancer Genetics and Cytogenetics. 56: 263-76. PMID 1756472 DOI: 10.1016/0165-4608(91)90179-X  0.434
1991 Lyons RM, Miller DA, Graycar JL, Moses HL, Derynck R. Differential binding of transforming growth factor-beta 1, -beta 2, and -beta 3 by fibroblasts and epithelial cells measured by affinity cross-linking of cell surface receptors. Molecular Endocrinology (Baltimore, Md.). 5: 1887-96. PMID 1665203 DOI: 10.1210/Mend-5-12-1887  0.495
1990 Lyons RM, Moses HL. Transforming growth factors and the regulation of cell proliferation. European Journal of Biochemistry. 187: 467-73. PMID 2406131 DOI: 10.1111/J.1432-1033.1990.Tb15327.X  0.415
1990 Miller DA, Pelton RW, Derynck R, Moses HL. Transforming growth factor-beta. A family of growth regulatory peptides. Annals of the New York Academy of Sciences. 593: 208-17. PMID 2375595 DOI: 10.1111/J.1749-6632.1990.Tb16113.X  0.505
1990 Perkett EA, Lyons RM, Moses HL, Brigham KL, Meyrick B. Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension. The Journal of Clinical Investigation. 86: 1459-64. PMID 2243124 DOI: 10.1172/Jci114862  0.46
1990 Moses HL, Yang EY, Pietenpol JA. TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell. 63: 245-7. PMID 2208284 DOI: 10.1016/0092-8674(90)90155-8  0.483
1990 Beauchamp RD, Lyons RM, Yang EY, Coffey RJ, Moses HL. Expression of and response to growth regulatory peptides by two human pancreatic carcinoma cell lines. Pancreas. 5: 369-80. PMID 2199964 DOI: 10.1097/00006676-199007000-00001  0.406
1990 Barnard JA, Lyons RM, Moses HL. The cell biology of transforming growth factor beta. Biochimica Et Biophysica Acta. 1032: 79-87. PMID 2194569 DOI: 10.1016/0304-419X(90)90013-Q  0.507
1990 Pietenpol JA, Holt JT, Stein RW, Moses HL. Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation. Proceedings of the National Academy of Sciences of the United States of America. 87: 3758-62. PMID 2187192 DOI: 10.1073/Pnas.87.10.3758  0.521
1990 Sipes NJ, Lyons RM, Moses HL. Isolation and characterization of Kirsten murine sarcoma virus-transformed mouse keratinocytes resistant to transforming growth factor beta. Molecular Carcinogenesis. 3: 12-9. PMID 2157456 DOI: 10.1002/Mc.2940030106  0.54
1990 Pietenpol JA, Stein RW, Moran E, Yaciuk P, Schlegel R, Lyons RM, Pittelkow MR, Münger K, Howley PM, Moses HL. TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell. 61: 777-85. PMID 2140528 DOI: 10.1016/0092-8674(90)90188-K  0.513
1990 Lyons RM, Gentry LE, Purchio AF, Moses HL. Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin. The Journal of Cell Biology. 110: 1361-7. PMID 2139036 DOI: 10.1083/Jcb.110.4.1361  0.475
1990 Torre-Amione G, Beauchamp RD, Koeppen H, Park BH, Schreiber H, Moses HL, Rowley DA. A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. Proceedings of the National Academy of Sciences of the United States of America. 87: 1486-90. PMID 2137615 DOI: 10.1073/Pnas.87.4.1486  0.433
1990 Pelton RW, Hogan BL, Miller DA, Moses HL. Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. Developmental Biology. 141: 456-60. PMID 1698672 DOI: 10.1016/0012-1606(90)90401-4  0.507
1990 Yang EY, Moses HL. Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane. The Journal of Cell Biology. 111: 731-41. PMID 1696268 DOI: 10.1083/Jcb.111.2.731  0.486
1990 Fava R, Casey T, Wilcox J, Pelton R, Moses H, Nanney L. Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules Blood. 76: 1946-1955. DOI: 10.1182/Blood.V76.10.1946.Bloodjournal76101946  0.449
1990 Fava R, Casey T, Wilcox J, Pelton R, Moses H, Nanney L. Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules Blood. 76: 1946-1955. DOI: 10.1182/blood.v76.10.1946.1946  0.341
1989 Keski-Oja J, Postlethwaite AE, Moses HL. Transforming growth factors in the regulation of malignant cell growth and invasion. Cancer Investigation. 6: 705-24. PMID 3072995 DOI: 10.3109/07357908809078038  0.421
1989 Fava R, Olsen N, Keski-Oja J, Moses H, Pincus T. Active and latent forms of transforming growth factor beta activity in synovial effusions. Journal of Experimental Medicine. 169: 291-296. PMID 2909658 DOI: 10.1084/Jem.169.1.291  0.476
1989 Whelan HT, Pledger WJ, Maciunas RJ, Galloway RL, Whetsell WO, Moses HL. Growth factors in the tumorigenicity of a brain tumor cell line. Pediatric Neurology. 5: 271-9. PMID 2803384 DOI: 10.1016/0887-8994(89)90017-9  0.429
1989 Miller DA, Lee A, Pelton RW, Chen EY, Moses HL, Derynck R. Murine transforming growth factor-beta 2 cDNA sequence and expression in adult tissues and embryos. Molecular Endocrinology (Baltimore, Md.). 3: 1108-14. PMID 2797004 DOI: 10.1210/Mend-3-7-1108  0.464
1989 Skinner MK, Moses HL. Transforming growth factor beta gene expression and action in the seminiferous tubule: peritubular cell-Sertoli cell interactions. Molecular Endocrinology (Baltimore, Md.). 3: 625-34. PMID 2725526 DOI: 10.1210/Mend-3-4-625  0.517
1989 Bascom CC, Sipes NJ, Coffey RJ, Moses HL. Regulation of epithelial cell proliferation by transforming growth factors. Journal of Cellular Biochemistry. 39: 25-32. PMID 2654145 DOI: 10.1002/Jcb.240390104  0.415
1989 Graycar JL, Miller DA, Arrick BA, Lyons RM, Moses HL, Derynck R. Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2. Molecular Endocrinology (Baltimore, Md.). 3: 1977-86. PMID 2628733 DOI: 10.1210/Mend-3-12-1977  0.507
1989 Miller DA, Lee A, Matsui Y, Chen EY, Moses HL, Derynck R. Complementary DNA cloning of the murine transforming growth factor-beta 3 (TGF beta 3) precursor and the comparative expression of TGF beta 3 and TGF beta 1 messenger RNA in murine embryos and adult tissues. Molecular Endocrinology (Baltimore, Md.). 3: 1926-34. PMID 2628730 DOI: 10.1210/Mend-3-12-1926  0.479
1989 Bascom CC, Wolfshohl JR, Coffey RJ, Madisen L, Webb NR, Purchio AR, Derynck R, Moses HL. Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2. Molecular and Cellular Biology. 9: 5508-15. PMID 2586525 DOI: 10.1128/Mcb.9.12.5508  0.481
1989 Barnard JA, Beauchamp RD, Coffey RJ, Moses HL. Regulation of intestinal epithelial cell growth by transforming growth factor type beta. Proceedings of the National Academy of Sciences of the United States of America. 86: 1578-82. PMID 2466294 DOI: 10.1073/Pnas.86.5.1578  0.524
1988 Moses HL, Coffey RJ, Leof EB, Lyons RM, Keski-Oja J. Transforming growth factor beta regulation of cell proliferation. Journal of Cellular Physiology. Supplement. 1-7. PMID 3316252 DOI: 10.1002/Jcp.1041330403  0.54
1988 Keski-Oja J, Blasi F, Leof EB, Moses HL. Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta. The Journal of Cell Biology. 106: 451-9. PMID 3276718 DOI: 10.1083/Jcb.106.2.451  0.51
1988 Russell WE, Coffey RJ, Ouellette AJ, Moses HL. Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat Proceedings of the National Academy of Sciences of the United States of America. 85: 5126-5130. PMID 3164865 DOI: 10.1073/Pnas.85.14.5126  0.47
1988 Blatti SP, Foster DN, Ranganathan G, Moses HL, Getz MJ. Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 1119-23. PMID 3124113 DOI: 10.1073/Pnas.85.4.1119  0.42
1988 Lyons RM, Keski-Oja J, Moses HL. Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. The Journal of Cell Biology. 106: 1659-65. PMID 2967299 DOI: 10.1083/Jcb.106.5.1659  0.48
1988 Pittelkow MR, Coffey RJ, Moses HL. Keratinocytes produce and are regulated by transforming growth factors. Annals of the New York Academy of Sciences. 548: 211-224. PMID 2470296 DOI: 10.1111/J.1749-6632.1988.Tb18809.X  0.367
1988 Coffey RJ, Bascom CC, Sipes NJ, Graves-Deal R, Weissman BE, Moses HL. Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β Molecular and Cellular Biology. 8: 3088-3093. PMID 2463471 DOI: 10.1128/Mcb.8.8.3088  0.532
1988 Barnard JA, Bascom CC, Lyons RM, Sipes NJ, Moses HL. Transforming growth factor beta in the control of epidermal proliferation. The American Journal of the Medical Sciences. 296: 159-63. PMID 2459967 DOI: 10.1097/00000441-198809000-00003  0.516
1987 Keski-Oja J, Leof EB, Lyons RM, Coffey RJ, Moses HL. Transforming growth factors and control of neoplastic cell growth. Journal of Cellular Biochemistry. 33: 95-107. PMID 3553215 DOI: 10.1002/Jcb.240330204  0.542
1987 Coffey RJ, Leof EB, Shipley GD, Moses HL. Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells Journal of Cellular Physiology. 132: 143-148. PMID 3496343 DOI: 10.1002/Jcp.1041320120  0.402
1987 Postlethwaite AE, Keski-Oja J, Moses HL, Kang AH. Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta. The Journal of Experimental Medicine. 165: 251-6. PMID 3491869 DOI: 10.1084/Jem.165.1.251  0.524
1987 Coffey RJ, Kost LJ, Lyons RM, Moses HL, LaRusso NF. Hepatic processing of transforming growth factor beta in the rat. Uptake, metabolism, and biliary excretion. The Journal of Clinical Investigation. 80: 750-7. PMID 3476497 DOI: 10.1172/JCI113130  0.359
1987 Leof EB, Proper JA, Moses HL. Modulation of transforming growth factor type beta action by activated ras and c-myc. Molecular and Cellular Biology. 7: 2649-52. PMID 3475570 DOI: 10.1128/MCB.7.7.2649  0.337
1987 Raghow R, Postlethwaite AE, Keski-Oja J, Moses HL, Kang AH. Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. The Journal of Clinical Investigation. 79: 1285-8. PMID 3470308 DOI: 10.1172/Jci112950  0.479
1987 Ranganathan G, Lyons R, Jiang NS, Moses H. Transforming growth factor type beta in normal human urine. Biochemical and Biophysical Research Communications. 148: 1503-12. PMID 3318836 DOI: 10.1016/S0006-291X(87)80302-9  0.334
1987 Skinner MK, Keski-Oja J, Osteen KG, Moses HL. Ovarian thecal cells produce transforming growth factor-beta which can regulate granulosa cell growth. Endocrinology. 121: 786-92. PMID 3297652 DOI: 10.1210/Endo-121-2-786  0.53
1987 Goustin AS, Nuttall GA, Leof EB, Ranganathan G, Moses HL. Transforming growth factor type beta can act as a potent competence factor for AKR-2B cells. Experimental Cell Research. 172: 293-303. PMID 2888675 DOI: 10.1016/0014-4827(87)90388-0  0.35
1987 Coffey RJ, Derynck R, Wilcox JN, Bringman TS, Goustin AS, Moses HL, Pittelkow MR. Production and auto-induction of transforming growth factor-alpha in human keratinocytes. Nature. 328: 817-20. PMID 2442615 DOI: 10.1038/328817A0  0.371
1987 Moses HL, Keski-Oja J, Coffey RJ, Lyons RM, Sipes NJ, Bascom CC. Transforming growth factors and oncogenes European Journal of Cancer and Clinical Oncology. 23: 1780. DOI: 10.1016/0277-5379(87)90651-1  0.358
1987 Keski-Oja J, Lyons RM, Moses HL. Transforming growth factor-β: A major regulator of cell growth and proteolytic activity European Journal of Cancer and Clinical Oncology. 23: 1767. DOI: 10.1016/0277-5379(87)90605-5  0.423
1986 Leof EB, Proper JA, Getz MJ, Moses HL. Transforming growth factor type beta regulation of actin mRNA. Journal of Cellular Physiology. 127: 83-8. PMID 3457016 DOI: 10.1002/JCP.1041270111  0.38
1986 Leof EB, Proper JA, Goustin AS, Shipley GD, DiCorleto PE, Moses HL. Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity. Proceedings of the National Academy of Sciences of the United States of America. 83: 2453-7. PMID 3010310 DOI: 10.1073/Pnas.83.8.2453  0.432
1985 Shipley GD, Tucker RF, Moses HL. Type β transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval Proceedings of the National Academy of Sciences of the United States of America. 82: 4147-4151. PMID 3858871 DOI: 10.1073/Pnas.82.12.4147  0.425
1984 Tucker RF, Branum EL, Shipley GD, Ryan RJ, Moses HL. Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets. Proceedings of the National Academy of Sciences of the United States of America. 81: 6757-61. PMID 6208555 DOI: 10.1073/Pnas.81.21.6757  0.501
1984 Tucker RF, Shipley GD, Moses HL, Holley RW. Growth inhibitor from BSC-1 cells closely related to platelet type β transforming growth factor Science. 226: 705-707. PMID 6093254 DOI: 10.1126/Science.6093254  0.475
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