Year |
Citation |
Score |
2020 |
Hosszu KK, Valentino A, Peerschke EI, Ghebrehiwet B. SLE: Novel Postulates for Therapeutic Options. Frontiers in Immunology. 11: 583853. PMID 33117397 DOI: 10.3389/fimmu.2020.583853 |
0.755 |
|
2020 |
Peerschke E, Stier K, Li X, Kandov E, de Stanchina E, Chang Q, Xiong Y, Manova-Todorova K, Fan N, Barlas A, Ghebrehiwet B, Adusumilli PS. gC1qR/HABP1/p32 Is a Potential New Therapeutic Target Against Mesothelioma. Frontiers in Oncology. 10: 1413. PMID 32903438 DOI: 10.3389/Fonc.2020.01413 |
0.335 |
|
2020 |
Ghebrehiwet B. Complement proteins in unexpected places: why we should be excited, not concerned! F1000research. 9. PMID 32148776 DOI: 10.12688/F1000Research.21690.1 |
0.383 |
|
2019 |
Ghebrehiwet B, Geisbrecht BV, Xu X, Savitt AG, Peerschke EIB. The C1q Receptors: Focus on gC1qR/p33 (C1qBP, p32, HABP-1). Seminars in Immunology. 101338. PMID 31744753 DOI: 10.1016/J.Smim.2019.101338 |
0.446 |
|
2018 |
Ghebrehiwet B, Kandov E, Kishore U, Peerschke EIB. Is the A-Chain the Engine That Drives the Diversity of C1q Functions? Revisiting Its Unique Structure. Frontiers in Immunology. 9: 162. PMID 29459870 DOI: 10.3389/Fimmu.2018.00162 |
0.313 |
|
2016 |
Pednekar L, Pandit H, Paudyal B, Kaur A, Al-Mozaini MA, Kouser L, Ghebrehiwet B, Mitchell DA, Madan T, Kishore U. Complement Protein C1q Interacts with DC-SIGN via Its Globular Domain and Thus May Interfere with HIV-1 Transmission. Frontiers in Immunology. 7: 600. PMID 28066413 DOI: 10.3389/Fimmu.2016.00600 |
0.368 |
|
2016 |
Pednekar L, Pathan AA, Paudyal B, Tsolaki AG, Kaur A, Abozaid SM, Kouser L, Khan HA, Peerschke EI, Shamji MH, Stenbeck G, Ghebrehiwet B, Kishore U. Analysis of the Interaction between Globular Head Modules of Human C1q and Its Candidate Receptor gC1qR. Frontiers in Immunology. 7: 567. PMID 28018340 DOI: 10.3389/Fimmu.2016.00567 |
0.384 |
|
2016 |
Ghebrehiwet B. The complement system: an evolution in progress. F1000research. 5: 2840. PMID 27990282 DOI: 10.12688/F1000Research.10065.1 |
0.336 |
|
2016 |
Ghebrehiwet B, Hosszu KH, Peerschke EI. C1q as an autocrine and paracrine regulator of cellular functions. Molecular Immunology. PMID 27914690 DOI: 10.1016/J.Molimm.2016.11.003 |
0.398 |
|
2016 |
Ghebrehiwet B, Kaplan AP, Joseph K, Peerschke EI. The complement and contact activation systems: partnership in pathogenesis beyond angioedema. Immunological Reviews. 274: 281-289. PMID 27782339 DOI: 10.1111/Imr.12469 |
0.396 |
|
2016 |
Pednekar L, Valentino A, Ji Y, Tumma N, Valentino C, Kadoor A, Hosszu KK, Ramadass M, Kew RR, Kishore U, Peerschke EI, Ghebrehiwet B. Identification of the gC1qR sites for the HIV-1 viral envelope protein gp41 and the HCV core protein: Implications in viral-specific pathogenesis and therapy. Molecular Immunology. 74: 18-26. PMID 27111569 DOI: 10.1016/J.Molimm.2016.03.016 |
0.763 |
|
2016 |
Moreau C, Bally I, Chouquet A, Bottazzi B, Ghebrehiwet B, Gaboriaud C, Thielens N. Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q. Frontiers in Immunology. 7: 79. PMID 26973654 DOI: 10.3389/Fimmu.2016.00079 |
0.388 |
|
2015 |
Rubenstein DA, Hom S, Ghebrehiwet B, Yin W. Tobacco and e-cigarette products initiate Kupffer cell inflammatory responses. Molecular Immunology. PMID 26072673 DOI: 10.1016/J.Molimm.2015.05.020 |
0.31 |
|
2015 |
Yin W, Ngwe EC, Ghebrehiwet B, Rubenstein DA. The combined effect of sidestream smoke and dynamic shear stress on endothelial cell inflammatory responses. Thrombosis Research. 135: 362-7. PMID 25467082 DOI: 10.1016/J.Thromres.2014.11.018 |
0.341 |
|
2015 |
Ramadass M, Ghebrehiwet B, Kew RR. Enhanced recognition of plasma proteins in a non-native state by complement C3b. A possible clearance mechanism for damaged proteins in blood. Molecular Immunology. 64: 55-62. PMID 25466612 DOI: 10.1016/J.Molimm.2014.10.022 |
0.372 |
|
2014 |
Peerschke EI, Ghebrehiwet B. cC1qR/CR and gC1qR/p33: observations in cancer. Molecular Immunology. 61: 100-9. PMID 25044096 DOI: 10.1016/J.Molimm.2014.06.011 |
0.351 |
|
2014 |
Ghebrehiwet B, Hosszu KK, Valentino A, Ji Y, Peerschke EI. Monocyte Expressed Macromolecular C1 and C1q Receptors as Molecular Sensors of Danger: Implications in SLE. Frontiers in Immunology. 5: 278. PMID 25018754 DOI: 10.3389/Fimmu.2014.00278 |
0.773 |
|
2014 |
Ramadass M, Ghebrehiwet B, Smith RJ, Kew RR. Generation of multiple fluid-phase C3b:plasma protein complexes during complement activation: possible implications in C3 glomerulopathies. Journal of Immunology (Baltimore, Md. : 1950). 192: 1220-30. PMID 24367026 DOI: 10.4049/Jimmunol.1302288 |
0.343 |
|
2014 |
Ghebrehiwet B, Ji Y, Valentino A, Pednekar L, Ramadass M, Habiel D, Kew RR, Hosszu KH, Galanakis DK, Kishore U, Peerschke EI. Soluble gC1qR is an autocrine signal that induces B1R expression on endothelial cells. Journal of Immunology (Baltimore, Md. : 1950). 192: 377-84. PMID 24319267 DOI: 10.4049/Jimmunol.1302031 |
0.413 |
|
2014 |
Ghebrehiwet B, Peerschke EI. Purification of C1q receptors and functional analysis. Methods in Molecular Biology (Clifton, N.J.). 1100: 319-27. PMID 24218271 DOI: 10.1007/978-1-62703-724-2_26 |
0.407 |
|
2013 |
Joseph K, Tholanikunnel BG, Bygum A, Ghebrehiwet B, Kaplan AP. Factor XII-independent activation of the bradykinin-forming cascade: Implications for the pathogenesis of hereditary angioedema types I and II. The Journal of Allergy and Clinical Immunology. 132: 470-5. PMID 23672780 DOI: 10.1016/J.Jaci.2013.03.026 |
0.307 |
|
2013 |
Ghebrehiwet B, Jesty J, Vinayagasundaram R, Vinayagasundaram U, Ji Y, Valentino A, Tumma N, Hosszu KH, Peerschke EI. Targeting gC1qR domains for therapy against infection and inflammation. Advances in Experimental Medicine and Biology. 735: 97-110. PMID 23402021 DOI: 10.1007/978-1-4614-4118-2_6 |
0.407 |
|
2012 |
Hosszu KK, Valentino A, Vinayagasundaram U, Vinayagasundaram R, Joyce MG, Ji Y, Peerschke EI, Ghebrehiwet B. DC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cells. Blood. 120: 1228-36. PMID 22700724 DOI: 10.1182/Blood-2011-07-369728 |
0.763 |
|
2012 |
Dembitzer FR, Kinoshita Y, Burstein D, Phelps RG, Beasley MB, Garcia R, Harpaz N, Jaffer S, Thung SN, Unger PD, Ghebrehiwet B, Peerschke EI. gC1qR expression in normal and pathologic human tissues: differential expression in tissues of epithelial and mesenchymal origin. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 60: 467-74. PMID 22638269 DOI: 10.1369/0022155412440882 |
0.344 |
|
2012 |
Hosszu KK, Valentino A, Ji Y, Matkovic M, Pednekar L, Rehage N, Tumma N, Peerschke EI, Ghebrehiwet B. Cell surface expression and function of the macromolecular c1 complex on the surface of human monocytes. Frontiers in Immunology. 3: 38. PMID 22566921 DOI: 10.3389/Fimmu.2012.00038 |
0.744 |
|
2012 |
Ghebrehiwet B, Hosszu KK, Valentino A, Peerschke EI. The C1q family of proteins: insights into the emerging non-traditional functions. Frontiers in Immunology. 3. PMID 22536204 DOI: 10.3389/Fimmu.2012.00052 |
0.73 |
|
2012 |
Peerschke EI, Ghebrehiwet B. Biochemical and functional comparison of platelet and raji cell clq receptors. Platelets. 3: 189-93. PMID 21043877 DOI: 10.3109/09537109209013182 |
0.374 |
|
2012 |
Pednekar L, Tumma N, Valentino C, Hosszu KK, Valentino A, Peerschke EI, Kishore U, Ghebrehiwet B. Identification of the gC1qR binding sites for HIV-1 gp41 and HCV core protein Immunobiology. 217: 1177. DOI: 10.1016/J.Imbio.2012.08.138 |
0.716 |
|
2011 |
Ghebrehiwet B, Jesty J, Xu S, Vinayagasundaram R, Vinayagasundaram U, Ji Y, Valentino A, Hosszu KK, Mathew S, Joseph K, Kaplan AP, Peerschke EI. Structure-function studies using deletion mutants identify domains of gC1qR/p33 as potential therapeutic targets for vascular permeability and inflammation. Frontiers in Immunology. 2. PMID 22282702 DOI: 10.3389/Fimmu.2011.00058 |
0.749 |
|
2011 |
Bossi F, Peerschke EI, Ghebrehiwet B, Tedesco F. Cross-talk between the complement and the kinin system in vascular permeability. Immunology Letters. 140: 7-13. PMID 21762728 DOI: 10.1016/J.Imlet.2011.06.006 |
0.333 |
|
2011 |
Pixley RA, Espinola RG, Ghebrehiwet B, Joseph K, Kao A, Bdeir K, Cines DB, Colman RW. Interaction of high-molecular-weight kininogen with endothelial cell binding proteins suPAR, gC1qR and cytokeratin 1 determined by surface plasmon resonance (BiaCore). Thrombosis and Haemostasis. 105: 1053-9. PMID 21544310 DOI: 10.1160/Th10-09-0591 |
0.413 |
|
2011 |
Sethi S, Herrmann M, Roller J, von Müller L, Peerschke EI, Ghebrehiwet B, Bajric I, Menger MD, Laschke MW. Blockade of gC1qR/p33, a receptor for C1q, inhibits adherence of Staphylococcus aureus to the microvascular endothelium. Microvascular Research. 82: 66-72. PMID 21539847 DOI: 10.1016/J.Mvr.2011.04.007 |
0.33 |
|
2010 |
Agostinis C, Bulla R, Tripodo C, Gismondi A, Stabile H, Bossi F, Guarnotta C, Garlanda C, De Seta F, Spessotto P, Santoni A, Ghebrehiwet B, Girardi G, Tedesco F. An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development. Journal of Immunology (Baltimore, Md. : 1950). 185: 4420-9. PMID 20810993 DOI: 10.4049/Jimmunol.0903215 |
0.382 |
|
2010 |
Peerschke EI, Yin W, Ghebrehiwet B. Complement activation on platelets: implications for vascular inflammation and thrombosis. Molecular Immunology. 47: 2170-5. PMID 20621693 DOI: 10.1016/J.Molimm.2010.05.009 |
0.331 |
|
2010 |
Kaplan AP, Ghebrehiwet B. The plasma bradykinin-forming pathways and its interrelationships with complement. Molecular Immunology. 47: 2161-9. PMID 20580091 DOI: 10.1016/J.Molimm.2010.05.010 |
0.413 |
|
2010 |
Hosszu KK, Santiago-Schwarz F, Peerschke EI, Ghebrehiwet B. Evidence that a C1q/C1qR system regulates monocyte-derived dendritic cell differentiation at the interface of innate and acquired immunity. Innate Immunity. 16: 115-27. PMID 19710097 DOI: 10.1177/1753425909339815 |
0.754 |
|
2010 |
Hosszu KK, Vinayagasundaram U, Vinayagasundaram R, Santiago-Schwarz F, Peerschke EI, Ghebrehiwet B. Co-localization of gC1qR with DC-SIGN on the surface of immature dendritic cells Molecular Immunology. 47: 2228-2229. DOI: 10.1016/J.Molimm.2010.05.098 |
0.735 |
|
2010 |
Hosszu KK, Vinayagasundaram U, Habiel D, Ji Y, Vinayagasundaram R, Peerschke EI, Ghebrehiwet B. Evidence that the full-length gC1qR (residues 1-282) is expressed on the cell surface Molecular Immunology. 47: 2223-2223. DOI: 10.1016/J.Molimm.2010.05.082 |
0.737 |
|
2009 |
Sansonno D, Tucci FA, Ghebrehiwet B, Lauletta G, Peerschke EI, Conteduca V, Russi S, Gatti P, Sansonno L, Dammacco F. Role of the receptor for the globular domain of C1q protein in the pathogenesis of hepatitis C virus-related cryoglobulin vascular damage. Journal of Immunology (Baltimore, Md. : 1950). 183: 6013-20. PMID 19828637 DOI: 10.4049/Jimmunol.0902038 |
0.332 |
|
2009 |
Bossi F, Fischetti F, Regoli D, Durigutto P, Frossi B, Gobeil F, Ghebrehiwet B, Peerschke EI, Cicardi M, Tedesco F. Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency. The Journal of Allergy and Clinical Immunology. 124: 1303-10.e4. PMID 19796797 DOI: 10.1016/J.Jaci.2009.08.007 |
0.36 |
|
2008 |
Yin W, Ghebrehiwet B, Peerschke EI. Expression of complement components and inhibitors on platelet microparticles. Platelets. 19: 225-33. PMID 18432523 DOI: 10.1080/09537100701777311 |
0.35 |
|
2008 |
Bulla R, Agostinis C, Bossi F, Rizzi L, Debeus A, Tripodo C, Radillo O, De Seta F, Ghebrehiwet B, Tedesco F. Decidual endothelial cells express surface-bound C1q as a molecular bridge between endovascular trophoblast and decidual endothelium. Molecular Immunology. 45: 2629-40. PMID 18295334 DOI: 10.1016/J.Molimm.2007.12.025 |
0.405 |
|
2008 |
Païdassi H, Tacnet-Delorme P, Garlatti V, Darnault C, Ghebrehiwet B, Gaboriaud C, Arlaud GJ, Frachet P. C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition. Journal of Immunology (Baltimore, Md. : 1950). 180: 2329-38. PMID 18250442 DOI: 10.4049/Jimmunol.180.4.2329 |
0.396 |
|
2008 |
Yin W, Ghebrehiwet B, Weksler B, Peerschke EI. Regulated complement deposition on the surface of human endothelial cells: effect of tobacco smoke and shear stress. Thrombosis Research. 122: 221-8. PMID 18166221 DOI: 10.1016/J.Thromres.2007.11.005 |
0.331 |
|
2008 |
Hosszu K, Santiago-Schwarz F, Peerschke E, Ghebrehiwet B. C1q is a molecular switch that regulates dendritic cell maturation at the monocyte-to-dendritic cell transition Molecular Immunology. 45: 4142-4143. DOI: 10.1016/J.Molimm.2008.08.143 |
0.732 |
|
2007 |
Ghebrehiwet B, Tantral L, Titmus MA, Panessa-Warren BJ, Tortora GT, Wong SS, Warren JB. The exosporium of B. cereus contains a binding site for gC1qR/p33: implication in spore attachment and/or entry. Advances in Experimental Medicine and Biology. 598: 181-97. PMID 17892212 DOI: 10.1007/978-0-387-71767-8_13 |
0.356 |
|
2007 |
Peerschke EI, Ghebrehiwet B. The contribution of gC1qR/p33 in infection and inflammation. Immunobiology. 212: 333-42. PMID 17544818 DOI: 10.1016/J.Imbio.2006.11.011 |
0.459 |
|
2007 |
Yin W, Ghebrehiwet B, Weksler B, Peerschke EI. Classical pathway complement activation on human endothelial cells. Molecular Immunology. 44: 2228-34. PMID 17173972 DOI: 10.1016/J.Molimm.2006.11.012 |
0.393 |
|
2007 |
Peerschke EI, Yin W, Alpert DR, Salmon JE, Roubey RA, Ghebrehiwet B. Enhanced Serum Complement Activation on Platelets Is Associated with Arterial Thrombosis in Patients with Systemic Lupus Erythematosus (SLE) and Antiphospholipid Antibodies(aPL). Blood. 110: 1637-1637. DOI: 10.1182/Blood.V110.11.1637.1637 |
0.302 |
|
2007 |
Païdassi H, Tacnet-Delorme P, Garlatti V, Darnault C, Ghebrehiwet B, Gaboriaud C, Arlaud GJ, Frachet P. C1q binds phosphatidylserine and likely acts as an early bridging molecule in apoptotic cell recognition and clearance Molecular Immunology. 44: 225-226. DOI: 10.1016/J.Molimm.2006.07.183 |
0.348 |
|
2006 |
Peerschke EI, Yin W, Grigg SE, Ghebrehiwet B. Blood platelets activate the classical pathway of human complement. Journal of Thrombosis and Haemostasis : Jth. 4: 2035-42. PMID 16961611 DOI: 10.1111/J.1538-7836.2006.02065.X |
0.331 |
|
2006 |
Ghebrehiwet B, CebadaMora C, Tantral L, Jesty J, Peerschke EI. gC1qR/p33 serves as a molecular bridge between the complement and contact activation systems and is an important catalyst in inflammation. Advances in Experimental Medicine and Biology. 586: 95-105. PMID 16893067 DOI: 10.1007/0-387-34134-X_7 |
0.458 |
|
2006 |
Peerschke EI, Bayer AS, Ghebrehiwet B, Xiong YQ. gC1qR/p33 blockade reduces Staphylococcus aureus colonization of target tissues in an animal model of infective endocarditis. Infection and Immunity. 74: 4418-23. PMID 16861627 DOI: 10.1128/Iai.01794-05 |
0.336 |
|
2006 |
Vegh Z, Kew RR, Gruber BL, Ghebrehiwet B. Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR. Molecular Immunology. 43: 1402-7. PMID 16140380 DOI: 10.1016/J.Molimm.2005.07.030 |
0.42 |
|
2006 |
Yin W, Kim J, Weksler BB, Ghebrehiwet B, Peerschke EI. Tobacco Smoke and Elevated Shear Stress Enhance Classical Pathway Complement Activation on Human Endothelial Cells. Blood. 108: 3934-3934. DOI: 10.1182/Blood.V108.11.3934.3934 |
0.301 |
|
2005 |
Baglia FA, Bradford HR, Colman RW, Peerschke EI, Ghebrehiwet B, Walsh PN. The Factor XI Receptor on Collagen Activated Platelets Is gC1qR/P33. Blood. 106: 690-690. DOI: 10.1182/Blood.V106.11.690.690 |
0.357 |
|
2005 |
Espinola RG, Pixley RA, Ghebrehiwet B, Joseph K, Kuo A, Cines DB, Colman RW. Interaction of High Molecular Weight Kininogen with Endothelial Cell Receptors suPAR, gC1qR and Cytokeratin 1 by Surface Plasmon Resonance (BiaCore). Blood. 106: 2666-2666. DOI: 10.1182/Blood.V106.11.2666.2666 |
0.308 |
|
2005 |
Yin W, Weksler B, Varon D, Savion N, Ghebrehiwet B, Peerschke E. Activation of the Classical Pathway of Complement by Resting and Shear Stress-Stimulated Human Endothelial Cells. Blood. 106: 2664-2664. DOI: 10.1182/Blood.V106.11.2664.2664 |
0.358 |
|
2004 |
Peerschke EI, Petrovan RJ, Ghebrehiwet B, Ruf W. Tissue factor pathway inhibitor-2 (TFPI-2) recognizes the complement and kininogen binding protein gC1qR/p33 (gC1qR): implications for vascular inflammation. Thrombosis and Haemostasis. 92: 811-9. PMID 15467913 DOI: 10.1160/Th04-03-0188 |
0.388 |
|
2004 |
Peerschke EI, Minta JO, Zhou SZ, Bini A, Gotlieb A, Colman RW, Ghebrehiwet B. Expression of gC1q-R/p33 and its major ligands in human atherosclerotic lesions. Molecular Immunology. 41: 759-66. PMID 15234555 DOI: 10.1016/J.Molimm.2004.04.020 |
0.315 |
|
2004 |
Ghebrehiwet B, Peerschke EI. cC1q-R (calreticulin) and gC1q-R/p33: ubiquitously expressed multi-ligand binding cellular proteins involved in inflammation and infection. Molecular Immunology. 41: 173-83. PMID 15159063 DOI: 10.1016/J.Molimm.2004.03.014 |
0.462 |
|
2004 |
Rubinstein DB, Stortchevoi A, Boosalis M, Ashfaq R, Ghebrehiwet B, Peerschke EI, Calvo F, Guillaume T. Receptor for the globular heads of C1q (gC1q-R, p33, hyaluronan-binding protein) is preferentially expressed by adenocarcinoma cells. International Journal of Cancer. 110: 741-50. PMID 15146564 DOI: 10.1002/Ijc.20105 |
0.394 |
|
2004 |
Ghebrehiwet B, Peerschke EI. Role of C1q and C1q receptors in the pathogenesis of systemic lupus erythematosus. Current Directions in Autoimmunity. 7: 87-97. PMID 14719376 DOI: 10.1159/000075688 |
0.412 |
|
2004 |
Joseph K, Tholanikunnel BG, Ghebrehiwet B, Kaplan AP. Interaction of high molecular weight kininogen binding proteins on endothelial cells. Thrombosis and Haemostasis. 91: 61-70. PMID 14691569 DOI: 10.1160/Th03-07-0471 |
0.379 |
|
2004 |
Takacs J, Panessa-Warren B, Wong SS, Warren J, Tortora G, Ghebrehiwet B. Blocking gC1q-Receptor Protein Alters L. monocytogenes Invasion in Caco-2 Cells Microscopy and Microanalysis. 10: 1530-1531. DOI: 10.1017/S1431927604884307 |
0.332 |
|
2003 |
Ghebrehiwet B, Feng X, Kumar R, Peerschke EI. Complement component C1q induces endothelial cell adhesion and spreading through a docking/signaling partnership of C1q receptors and integrins. International Immunopharmacology. 3: 299-310. PMID 12639807 DOI: 10.1016/S1567-5769(02)00270-9 |
0.423 |
|
2003 |
Peerschke EI, Murphy TK, Ghebrehiwet B. Activation-dependent surface expression of gC1qR/p33 on human blood platelets. Thrombosis and Haemostasis. 89: 331-9. PMID 12574814 DOI: 10.1055/S-0037-1613450 |
0.393 |
|
2003 |
Vegh Z, Goyarts EC, Rozengarten K, Mazumder A, Ghebrehiwet B. Maturation-dependent expression of C1q binding proteins on the cell surface of human monocyte-derived dendritic cells. International Immunopharmacology. 3: 39-51. PMID 12538033 DOI: 10.1016/S1567-5769(02)00211-4 |
0.41 |
|
2003 |
Panessa-Warren B, Tortora G, Ghebrehiwet B, Wong S, Warren J. Bacillus and Clostridium Spore Attachment/ Entry of Human Colon Cells Microscopy and Microanalysis. 9: 1378-1379. DOI: 10.1017/S1431927603446898 |
0.3 |
|
2003 |
Grace KS, Bronson RA, Ghebrehiwet B. Ligation of the C1q receptor, gC1qR/p33, associates with both the αvβ3 integrin and vitronectin and causes protein phosphorylation Fertility and Sterility. 80: 5-6. DOI: 10.1016/S0015-0282(03)01815-6 |
0.732 |
|
2002 |
Ghebrehiwet B, Jesty J, Peerschke EI. gC1q-R/p33: structure-function predictions from the crystal structure. Immunobiology. 205: 421-32. PMID 12396004 DOI: 10.1078/0171-2985-00143 |
0.386 |
|
2002 |
Rozanov DV, Ghebrehiwet B, Ratnikov B, Monosov EZ, Deryugina EI, Strongin AY. The cytoplasmic tail peptide sequence of membrane type-1 matrix metalloproteinase (MT1-MMP) directly binds to gC1qR, a compartment-specific chaperone-like regulatory protein. Febs Letters. 527: 51-7. PMID 12220632 DOI: 10.1016/S0014-5793(02)03153-8 |
0.323 |
|
2002 |
Kumar R, Peerschke EI, Ghebrehiwet B. Zinc induces exposure of hydrophobic sites in the C-terminal domain of gC1q-R/p33. Molecular Immunology. 39: 69-75. PMID 12213329 DOI: 10.1016/S0161-5890(02)00046-9 |
0.35 |
|
2002 |
Mohan KV, Ghebrehiwet B, Atreya CD. The N-terminal conserved domain of rubella virus capsid interacts with the C-terminal region of cellular p32 and overexpression of p32 enhances the viral infectivity. Virus Research. 85: 151-61. PMID 12034482 DOI: 10.1016/S0168-1702(02)00030-8 |
0.324 |
|
2002 |
Grace KS, Bronson RA, Ghebrehiwet B. Surface expression of complement receptor gC1q-R/p33 is increased on the plasma membrane of human spermatozoa after capacitation. Biology of Reproduction. 66: 823-9. PMID 11870091 DOI: 10.1095/Biolreprod66.3.823 |
0.747 |
|
2002 |
Feng X, Tonnesen MG, Peerschke EI, Ghebrehiwet B. Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading. Journal of Immunology (Baltimore, Md. : 1950). 168: 2441-8. PMID 11859136 DOI: 10.4049/Jimmunol.168.5.2441 |
0.355 |
|
2002 |
Rozanov DV, Ghebrehiwet B, Postnova TI, Eichinger A, Deryugina EI, Strongin AY. The hemopexin-like C-terminal domain of membrane type 1 matrix metalloproteinase regulates proteolysis of a multifunctional protein, gC1qR. The Journal of Biological Chemistry. 277: 9318-25. PMID 11773076 DOI: 10.1074/Jbc.M110711200 |
0.325 |
|
2001 |
Ogden CA, deCathelineau A, Hoffmann PR, Bratton D, Ghebrehiwet B, Fadok VA, Henson PM. C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. The Journal of Experimental Medicine. 194: 781-95. PMID 11560994 DOI: 10.1084/Jem.194.6.781 |
0.431 |
|
2001 |
Ghebrehiwet B, Lim BL, Kumar R, Feng X, Peerschke EI. gC1q-R/p33, a member of a new class of multifunctional and multicompartmental cellular proteins, is involved in inflammation and infection. Immunological Reviews. 180: 65-77. PMID 11414365 DOI: 10.1034/J.1600-065X.2001.1800106.X |
0.395 |
|
2001 |
Peerschke EI, Ghebrehiwet B. Human blood platelet gC1qR/p33. Immunological Reviews. 180: 56-64. PMID 11414364 DOI: 10.1034/J.1600-065X.2001.1800105.X |
0.319 |
|
2001 |
Szabó J, Cervenák L, Tóth FD, Prohászka Z, Horváth L, Kerekes K, Beck Z, Bácsi A, Erdei A, Peerschke EI, Füst G, Ghebrehiwet B. Soluble gC1q-R/p33, a cell protein that binds to the globular "heads" of C1q, effectively inhibits the growth of HIV-1 strains in cell cultures. Clinical Immunology (Orlando, Fla.). 99: 222-31. PMID 11318594 DOI: 10.1006/Clim.2001.5013 |
0.327 |
|
2001 |
Kaplan AP, Joseph K, Shibayama Y, Reddigari S, Ghebrehiwet B. Activation of the plasma kinin forming cascade along cell surfaces. International Archives of Allergy and Immunology. 124: 339-42. PMID 11307009 DOI: 10.1159/000053751 |
0.381 |
|
2001 |
Joseph K, Ghebrehiwet B, Kaplan AP. Activation of the kinin-forming cascade on the surface of endothelial cells. Biological Chemistry. 382: 71-5. PMID 11258676 DOI: 10.1515/Bc.2001.012 |
0.321 |
|
2001 |
Joseph K, Shibayama Y, Ghebrehiwet B, Kaplan A. Factor XII-dependent Contact Activation on Endothelial Cells and Binding Proteins gC1qR and Cytokeratin 1 Thrombosis and Haemostasis. 85: 119-124. DOI: 10.1055/S-0037-1612914 |
0.399 |
|
2000 |
Storz P, Hausser A, Link G, Dedio J, Ghebrehiwet B, Pfizenmaier K, Johannes FJ. Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32. The Journal of Biological Chemistry. 275: 24601-7. PMID 10831594 DOI: 10.1074/Jbc.M002964200 |
0.332 |
|
2000 |
Braun L, Ghebrehiwet B, Cossart P. gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes. The Embo Journal. 19: 1458-66. PMID 10747014 DOI: 10.1093/Emboj/19.7.1458 |
0.386 |
|
2000 |
Nguyen T, Ghebrehiwet B, Peerschke EI. Staphylococcus aureus protein A recognizes platelet gC1qR/p33: a novel mechanism for staphylococcal interactions with platelets. Infection and Immunity. 68: 2061-8. PMID 10722602 DOI: 10.1128/Iai.68.4.2061-2068.2000 |
0.374 |
|
2000 |
Joseph K, Shibayama Y, Nakazawa Y, Peerschke EI, Ghebrehiwet B, Kaplan AP. Interaction of factor XII and high molecular weight kininogen with cytokeratin 1 and gC1qR of vascular endothelial cells and with aggregated Abeta protein of Alzheimer's disease. Immunopharmacology. 43: 203-10. PMID 10596854 DOI: 10.1016/S0162-3109(99)00136-8 |
0.387 |
|
2000 |
Ogden CA, Ghebrehiwet B, Fadok V, Henson P. C1Q mediates the clearance of apoptotic cells Immunopharmacology. 49: 40. DOI: 10.1016/S0162-3109(00)80111-3 |
0.335 |
|
2000 |
Kaplan AP, Joseph K, Shibayama Y, Reddigari S, Ghebrehiwet B. Activation of the Plasma-Kinin-Forming Cascade Along Cell Surfaces Allergo Journal. 9: 407-410. DOI: 10.1007/Bf03370270 |
0.378 |
|
1999 |
Joseph K, Ghebrehiwet B, Kaplan AP. Cytokeratin 1 and gC1qR mediate high molecular weight kininogen binding to endothelial cells. Clinical Immunology (Orlando, Fla.). 92: 246-55. PMID 10479529 DOI: 10.1006/Clim.1999.4753 |
0.362 |
|
1999 |
Guo WX, Ghebrehiwet B, Weksler B, Schweitzer K, Peerschke EI. Up-regulation of endothelial cell binding proteins/receptors for complement component C1q by inflammatory cytokines. The Journal of Laboratory and Clinical Medicine. 133: 541-50. PMID 10360628 DOI: 10.1016/S0022-2143(99)90183-X |
0.407 |
|
1999 |
Lu PD, Galanakis DK, Ghebrehiwet B, Peerschke EI. The receptor for the globular "heads" of C1q, gC1q-R, binds to fibrinogen/fibrin and impairs its polymerization. Clinical Immunology (Orlando, Fla.). 90: 360-7. PMID 10075865 DOI: 10.1006/Clim.1998.4660 |
0.323 |
|
1999 |
Peerschke EI, Ghebrehiwet B. Platelet receptors for the complement component C1q: implications for hemostasis and thrombosis. Immunobiology. 199: 239-49. PMID 9777409 DOI: 10.1016/S0171-2985(98)80030-2 |
0.359 |
|
1999 |
Ghebrehiwet B, Peerschke EI. Structure and function of gC1q-R: a multiligand binding cellular protein. Immunobiology. 199: 225-38. PMID 9777408 DOI: 10.1016/S0171-2985(98)80029-6 |
0.391 |
|
1999 |
Joseph K, Nakazawa Y, Bahou WF, Ghebrehiwet B, Kaplan AP. Platelet Glycoprotein Ib: A Zinc-Dependent Binding Protein for the Heavy Chain of High-Molecular-Weight Kininogen Molecular Medicine. 5: 555-563. DOI: 10.1007/Bf03401982 |
0.373 |
|
1998 |
Bronson R, Bronson S, Oula L, Zhang W, Ghebrehiwet B. Detection of complement C1q receptors on human spermatozoa. Journal of Reproductive Immunology. 38: 1-14. PMID 9616874 DOI: 10.1016/S0165-0378(98)00006-0 |
0.359 |
|
1998 |
Tan X, Wong ST, Ghebrehiwet B, Storm DR, Bordin S. Complement C1q inhibits cellular spreading and stimulates adenylyl cyclase activity of fibroblasts. Clinical Immunology and Immunopathology. 87: 193-204. PMID 9614935 DOI: 10.1006/Clin.1997.4485 |
0.385 |
|
1998 |
Peerschke EIB, Jesty J, Reid KBM, Ghebrehiwet B. The soluble recombinant form of a binding protein/receptor for the globular domain of C1q (gC1qR) enhances blood coagulation Blood Coagulation and Fibrinolysis. 9: 29-37. PMID 9607116 DOI: 10.1097/00001721-199801000-00004 |
0.342 |
|
1998 |
Leigh LE, Ghebrehiwet B, Perera TP, Bird IN, Strong P, Kishore U, Reid KB, Eggleton P. C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms. The Biochemical Journal. 330: 247-54. PMID 9461517 DOI: 10.1042/Bj3300247 |
0.404 |
|
1997 |
Kaplan AP, Joseph K, Shibayama Y, Reddigari S, Ghebrehiwet B, Silverberg M. The intrinsic coagulation/kinin-forming cascade: assembly in plasma and cell surfaces in inflammation. Advances in Immunology. 66: 225-72. PMID 9328643 DOI: 10.1016/S0065-2776(08)60599-4 |
0.385 |
|
1997 |
Peterson KL, Zhang W, Lu PD, Keilbaugh SA, Peerschke EIB, Ghebrehiwet B. The C1q-binding cell membrane proteins cC1q-R and gC1q-R are released from activated cells: Subcellular distribution and immunochemical characterization Clinical Immunology and Immunopathology. 84: 17-26. PMID 9191880 DOI: 10.1006/Clin.1997.4374 |
0.372 |
|
1996 |
Kuna P, Iyer M, Peerschke EI, Kaplan AP, Reid KB, Ghebrehiwet B. Human C1q induces eosinophil migration. Clinical Immunology and Immunopathology. 81: 48-54. PMID 8808641 DOI: 10.1006/Clin.1996.0156 |
0.343 |
|
1996 |
Joseph K, Ghebrehiwet B, Peerschke EI, Reid KB, Kaplan AP. Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular "heads" of C1q (gC1q-R). Proceedings of the National Academy of Sciences of the United States of America. 93: 8552-7. PMID 8710908 DOI: 10.1073/Pnas.93.16.8552 |
0.405 |
|
1996 |
GHEBREHIWET B, LU PD, ZHANG W, LIM B, EGGLETON P, LEIGH LE, REID KB, PEERSCHKE EI. Identification of Functional Domains on gClQ-R, a Cell Surface Protein That Binds to the Globular "Heads" of C1Q, Using Monoclonal Antibodies and Synthetic Peptides Hybridoma. 15: 333-342. DOI: 10.1089/Hyb.1996.15.333 |
0.365 |
|
1996 |
Lim B, Reid KBM, Ghebrehiwet B, Peerschke EIB, Leigh LAE, Preissner KT. The Binding Protein for Globular Heads of Complement C1q, gC1qR Journal of Biological Chemistry. 271: 26739-26744. DOI: 10.1074/Jbc.271.43.26739 |
0.39 |
|
1995 |
Eggleton P, Ghebrehiwet B, Sastry KN, Coburn JP, Zaner KS, Reid KBM, Tauber AI. Identification of a gC1q-binding protein (gC1q-R) on the surface of human neutrophils: Subcellular localization and binding properties in comparison with the cC1q-R Journal of Clinical Investigation. 95: 1569-1578. PMID 7706463 DOI: 10.1172/Jci117830 |
0.401 |
|
1994 |
Galanakis DK, Ghebrehiwet B. A unique property of a plasma proteoglycan, the C1q inhibitor. An anticoagulant state resulting from its binding to fibrinogen. The Journal of Clinical Investigation. 93: 303-10. PMID 8282801 DOI: 10.1172/Jci116960 |
0.332 |
|
1994 |
Ghebrehiwet B, Lim BL, Peerschke EI, Willis AC, Reid KB. Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q. The Journal of Experimental Medicine. 179: 1809-21. PMID 8195709 DOI: 10.1084/Jem.179.6.1809 |
0.382 |
|
1994 |
Eggleton P, Ghebrehiwet B, Coburn JP, Sastry KN, Zaner KS, Tauber AI. Characterization of the human neutrophil C1q receptor and functional effects of free ligand on activated neutrophils Blood. 84: 1640-1649. PMID 8068954 DOI: 10.1182/Blood.V84.5.1640.1640 |
0.418 |
|
1994 |
Eggleton P, Lieu TS, Zappi EG, Sastry K, Coburn J, Zaner KS, Sontheimer RD, Capra JD, Ghebrehiwet B, Tauber AI. Calreticulin is released from activated neutrophils and binds to C1q and mannan-binding protein Clinical Immunology and Immunopathology. 72: 405-409. PMID 8062452 DOI: 10.1006/Clin.1994.1160 |
0.415 |
|
1994 |
Eggleton P, Ghebrehiwet B, Coburn J, Sastry K, Zaner K, Tauber A. Characterization of the human neutrophil C1q receptor and functional effects of free ligand on activated neutrophils Blood. 84: 1640-1649. DOI: 10.1182/BLOOD.V84.5.1640.1640 |
0.306 |
|
1993 |
Peerschke EI, Malhotra R, Ghebrehiwet B, Reid KB, Willis AC, Sim RB. Isolation of a human endothelial cell C1q receptor (C1qR). Journal of Leukocyte Biology. 53: 179-84. PMID 8445329 DOI: 10.1002/Jlb.53.2.179 |
0.317 |
|
1993 |
Peerschke EI, Reid KB, Ghebrehiwet B. Platelet activation by C1q results in the induction of alpha IIb/beta 3 integrins (GPIIb-IIIa) and the expression of P-selectin and procoagulant activity. The Journal of Experimental Medicine. 178: 579-87. PMID 7688027 DOI: 10.1084/Jem.178.2.579 |
0.346 |
|
1992 |
Hong YQ, Ghebrehiwet B. Effect of Pseudomonas aeruginosa elastase and alkaline protease on serum complement and isolated components C1q and C3. Clinical Immunology and Immunopathology. 62: 133-8. PMID 1730152 DOI: 10.1016/0090-1229(92)90065-V |
0.322 |
|
1992 |
Peerschke EI, Ghebrehiwet B. Platelet interactions with C1q in whole blood and in the presence of immune complexes or aggregated IgG. Clinical Immunology and Immunopathology. 63: 45-50. PMID 1591882 DOI: 10.1016/0090-1229(92)90092-3 |
0.353 |
|
1992 |
Hong Y, Kim CW, Ghebrehiwet B. Trichinella spiralis: activation of complement by infective larvae, adults, and newborn larvae. Experimental Parasitology. 74: 290-9. PMID 1582481 DOI: 10.1016/0014-4894(92)90152-Z |
0.32 |
|
1992 |
Ghebrehiwet B, Peerschke EI, Hong Y, Munoz P, Gorevic PD. Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV. Journal of Leukocyte Biology. 51: 546-56. PMID 1377218 DOI: 10.1002/Jlb.51.6.546 |
0.347 |
|
1990 |
Ghebrehiwet B, Habicht GS, Beck G. Interaction of C1q with its receptor on cultured cell lines induces an anti-proliferative response. Clinical Immunology and Immunopathology. 54: 148-60. PMID 2293904 DOI: 10.1016/0090-1229(90)90014-H |
0.363 |
|
1988 |
Ghebrehiwet B, Bossone S, Erdei A, Reid KB. Reversible biotinylation of C1q with a cleavable biotinyl derivative. Application in C1q receptor (C1qR) purification. Journal of Immunological Methods. 110: 251-60. PMID 3259972 DOI: 10.1016/0022-1759(88)90111-1 |
0.307 |
|
1988 |
Randazzo BP, Fleit HB, Kaplan AP, Ghebrehiwet B. Expression of functional cell surface C1-inactivator by U937 cells. Clinical Immunology and Immunopathology. 49: 463-77. PMID 3191617 DOI: 10.1016/0090-1229(88)90133-X |
0.41 |
|
1984 |
Ghebrehiwet B, Silvestri L, McDevitt C. Identification of the Raji cell membrane-derived C1q inhibitor as a receptor for human C1q. Purification and immunochemical characterization. The Journal of Experimental Medicine. 160: 1375-89. PMID 6436431 DOI: 10.1084/Jem.160.5.1375 |
0.385 |
|
1983 |
Fields TR, Abramson SB, Weissmann G, Kaplan AP, Ghebrehiwet B. Activation of the alternative pathway of complement by monosodium urate crystals Clinical Immunology and Immunopathology. 26: 249-257. PMID 6872344 DOI: 10.1016/0090-1229(83)90143-5 |
0.312 |
|
1983 |
Ghebrehiwet B, Randazzo BP, Dunn JT, Silverberg M, Kaplan AP. Mechanisms of activation of the classical pathway of complement by Hageman factor fragment. The Journal of Clinical Investigation. 71: 1450-6. PMID 6304147 DOI: 10.1172/Jci110898 |
0.309 |
|
1983 |
Fields T, Ghebrehiwet B, Kaplan AP. Kinin formation in hereditary angioedema plasma: evidence against kinin derivation from C2 and in support of "spontaneous" formation of bradykinin. The Journal of Allergy and Clinical Immunology. 72: 54-60. PMID 6222104 DOI: 10.1016/0091-6749(83)90052-0 |
0.306 |
|
1982 |
Kaplan AP, Silverberg M, Dunn JT, Ghebrehiwet B. Interaction of the clotting, Kinin-forming, complement, and fibrinolytic pathways in inflammation Annals of the New York Academy of Sciences. 25-38. PMID 7046578 DOI: 10.1111/J.1749-6632.1982.Tb22123.X |
0.307 |
|
1981 |
Ghebrehiwet B, Silverberg M, Kaplan AP. Activation of the classical pathway of complement by Hageman factor fragment Journal of Experimental Medicine. 153: 665-676. PMID 7252410 DOI: 10.1084/Jem.153.3.665 |
0.312 |
|
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