Michael S. Parmacek - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kodama T, Marian TA, Lee H, Kodama M, Li J, Parmacek MS, Jenkins NA, Copeland NG, Wei Z. MRTFB suppresses colorectal cancer development through regulating SPDL1 and MCAM. Proceedings of the National Academy of Sciences of the United States of America. PMID 31690663 DOI: 10.1073/Pnas.1910413116  0.352
2015 Huang J, Wang T, Wright AC, Yang J, Zhou S, Li L, Yang J, Small A, Parmacek MS. Myocardin is required for maintenance of vascular and visceral smooth muscle homeostasis during postnatal development. Proceedings of the National Academy of Sciences of the United States of America. 112: 4447-52. PMID 25805819 DOI: 10.1073/Pnas.1420363112  0.488
2015 Bauer RC, Tohyama J, Cui J, Cheng L, Yang J, Zhang X, Ou K, Paschos GK, Zheng XL, Parmacek MS, Rader DJ, Reilly MP. Knockout of Adamts7, a novel coronary artery disease locus in humans, reduces atherosclerosis in mice. Circulation. 131: 1202-13. PMID 25712206 DOI: 10.1161/Circulationaha.114.012669  0.359
2014 Liu C, Morishima M, Jiang X, Yu T, Meng K, Ray D, Pao A, Ye P, Parmacek MS, Yu YE. Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice. Human Genetics. 133: 743-53. PMID 24362460 DOI: 10.1007/S00439-013-1407-Z  0.335
2013 Branchetti E, Poggio P, Sainger R, Shang E, Grau JB, Jackson BM, Lai EK, Parmacek MS, Gorman RC, Gorman JH, Bavaria JE, Ferrari G. Oxidative stress modulates vascular smooth muscle cell phenotype via CTGF in thoracic aortic aneurysm. Cardiovascular Research. 100: 316-24. PMID 23985903 DOI: 10.1093/Cvr/Cvt205  0.365
2013 Parmacek MS, Epstein JA. An epigenetic roadmap for cardiomyocyte differentiation. Circulation Research. 112: 881-3. PMID 23493303 DOI: 10.1161/Circresaha.113.301134  0.448
2013 Nguyen AT, Gomez D, Bell RD, Campbell JH, Clowes AW, Gabbiani G, Giachelli CM, Parmacek MS, Raines EW, Rusch NJ, Speer MY, Sturek M, Thyberg J, Towler DA, Weiser-Evans MC, et al. Smooth muscle cell plasticity: fact or fiction? Circulation Research. 112: 17-22. PMID 23093573 DOI: 10.1161/Circresaha.112.281048  0.415
2012 Huang J, Elicker J, Bowens N, Liu X, Cheng L, Cappola TP, Zhu X, Parmacek MS. Myocardin regulates BMP10 expression and is required for heart development. The Journal of Clinical Investigation. 122: 3678-91. PMID 22996691 DOI: 10.1172/Jci63635  0.492
2012 Huang J, Parmacek MS. Modulation of smooth muscle cell phenotype: the other side of the story. Circulation Research. 111: 659-61. PMID 22935528 DOI: 10.1161/Circresaha.112.277368  0.533
2012 Li J, Bowens N, Cheng L, Zhu X, Chen M, Hannenhalli S, Cappola TP, Parmacek MS. Myocardin-like protein 2 regulates TGFβ signaling in embryonic stem cells and the developing vasculature. Development (Cambridge, England). 139: 3531-42. PMID 22899851 DOI: 10.1242/Dev.082222  0.525
2012 Rong L, Liu J, Qi Y, Graham AM, Parmacek MS, Li S. GATA-6 promotes cell survival by up-regulating BMP-2 expression during embryonic stem cell differentiation Molecular Biology of the Cell. 23: 3754-3763. PMID 22855527 DOI: 10.1091/Mbc.E12-04-0313  0.443
2012 Rader DJ, Parmacek MS. Secreted miRNAs suppress atherogenesis Nature Cell Biology. 14: 233-235. PMID 22373869 DOI: 10.1038/Ncb2452  0.326
2012 Bowens N, Parmacek MS. Chapter 82 – Development of the Smooth Muscle Cell Lineage Musclefundamental Biology and Mechanisms of Disease. 1109-1116. DOI: 10.1016/B978-0-12-381510-1.00082-X  0.536
2011 Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD, Dedhar S, Parmacek MS, Gerszten RE. Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circulation Research. 109: 616-28. PMID 21778429 DOI: 10.1161/Circresaha.110.239343  0.334
2011 Liu C, Morishima M, Yu T, Matsui S, Zhang L, Fu D, Pao A, Costa AC, Gardiner KJ, Cowell JK, Nowak NJ, Nowak NJ, Parmacek MS, Liang P, Baldini A, et al. Genetic analysis of Down syndrome-associated heart defects in mice. Human Genetics. 130: 623-32. PMID 21442329 DOI: 10.1007/S00439-011-0980-2  0.333
2010 Parmacek MS. Myocardin-related transcription factor-A: mending a broken heart. Circulation Research. 107: 168-70. PMID 20651293 DOI: 10.1161/Circresaha.110.224881  0.306
2009 Huang J, Min Lu M, Cheng L, Yuan LJ, Zhu X, Stout AL, Chen M, Li J, Parmacek MS. Myocardin is required for cardiomyocyte survival and maintenance of heart function. Proceedings of the National Academy of Sciences of the United States of America. 106: 18734-9. PMID 19850880 DOI: 10.1073/Pnas.0910749106  0.456
2009 Parmacek MS. MicroRNA-modulated targeting of vascular smooth muscle cells. The Journal of Clinical Investigation. 119: 2526-8. PMID 19690387 DOI: 10.1172/Jci40503  0.393
2009 Beppu H, Malhotra R, Beppu Y, Lepore JJ, Parmacek MS, Bloch KD. BMP type II receptor regulates positioning of outflow tract and remodeling of atrioventricular cushion during cardiogenesis. Developmental Biology. 331: 167-75. PMID 19409885 DOI: 10.1016/J.Ydbio.2009.04.032  0.401
2008 Parmacek MS. Myocardin: dominant driver of the smooth muscle cell contractile phenotype. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1416-7. PMID 18650504 DOI: 10.1161/Atvbaha.108.168930  0.536
2008 Zhang Y, Goss AM, Cohen ED, Kadzik R, Lepore JJ, Muthukumaraswamy K, Yang J, DeMayo FJ, Whitsett JA, Parmacek MS, Morrisey EE. A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration. Nature Genetics. 40: 862-70. PMID 18536717 DOI: 10.1038/Ng.157  0.346
2008 Huang J, Cheng L, Li J, Chen M, Zhou D, Lu MM, Proweller A, Epstein JA, Parmacek MS. Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice. The Journal of Clinical Investigation. 118: 515-25. PMID 18188448 DOI: 10.1172/Jci33304  0.452
2007 Proweller A, Wright AC, Horng D, Cheng L, Lu MM, Lepore JJ, Pear WS, Parmacek MS. Notch signaling in vascular smooth muscle cells is required to pattern the cerebral vasculature. Proceedings of the National Academy of Sciences of the United States of America. 104: 16275-80. PMID 17909179 DOI: 10.1073/Pnas.0707950104  0.357
2007 Mohler ER, Fang Y, Shaffer RG, Moore J, Wilensky RL, Parmacek M, Levitan I. Hypercholesterolemia suppresses Kir channels in porcine bone marrow progenitor cells in vivo. Biochemical and Biophysical Research Communications. 358: 317-24. PMID 17482574 DOI: 10.1016/J.Bbrc.2007.04.138  0.325
2007 Parmacek MS. Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation. Circulation Research. 100: 633-44. PMID 17363709 DOI: 10.1161/01.Res.0000259563.61091.E8  0.525
2007 High FA, Zhang M, Proweller A, Tu L, Parmacek MS, Pear WS, Epstein JA. An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation. The Journal of Clinical Investigation. 117: 353-63. PMID 17273555 DOI: 10.1172/Jci30070  0.504
2007 Proweller A, Wright AC, Wang T, Pear W, Parmacek MS. Vascular abnormalities revealed by Notch signaling‐deficient vascular smooth muscle in mice The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A67-B  0.384
2006 Hannenhalli S, Putt ME, Gilmore JM, Wang J, Parmacek MS, Epstein JA, Morrisey EE, Margulies KB, Cappola TP. Transcriptional genomics associates FOX transcription factors with human heart failure. Circulation. 114: 1269-76. PMID 16952980 DOI: 10.1161/Circulationaha.106.632430  0.37
2006 Proweller A, Tu L, Lepore JJ, Cheng L, Lu MM, Seykora J, Millar SE, Pear WS, Parmacek MS. Impaired notch signaling promotes de novo squamous cell carcinoma formation. Cancer Research. 66: 7438-44. PMID 16885339 DOI: 10.1158/0008-5472.Can-06-0793  0.361
2006 Camoretti-Mercado B, Fernandes DJ, Dewundara S, Churchill J, Ma L, Kogut PC, McConville JF, Parmacek MS, Solway J. Inhibition of transforming growth factor beta-enhanced serum response factor-dependent transcription by SMAD7. The Journal of Biological Chemistry. 281: 20383-92. PMID 16690609 DOI: 10.1074/Jbc.M602748200  0.428
2006 Lepore JJ, Mericko PA, Cheng L, Lu MM, Morrisey EE, Parmacek MS. GATA-6 regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis. The Journal of Clinical Investigation. 116: 929-39. PMID 16557299 DOI: 10.1172/Jci27363  0.482
2006 Iyer D, Chang D, Marx J, Wei L, Olson EN, Parmacek MS, Balasubramanyam A, Schwartz RJ. Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. Proceedings of the National Academy of Sciences of the United States of America. 103: 4516-21. PMID 16537394 DOI: 10.1073/Pnas.0505338103  0.447
2006 Milewski RKC, Hamamoto H, Kanemoto S, Immanuel C, Plappert T, Parmacek MS, Gorman JH, Gorman RC. Serum Response Factor Is Regionally Expressed in Ischemic Cardiomyopathy Journal of Cardiac Failure. 12. DOI: 10.1016/J.Cardfail.2006.06.154  0.325
2005 Capo-Chichi CD, Rula ME, Smedberg JL, Vanderveer L, Parmacek MS, Morrisey EE, Godwin AK, Xu XX. Perception of differentiation cues by GATA factors in primitive endoderm lineage determination of mouse embryonic stem cells. Developmental Biology. 286: 574-86. PMID 16162334 DOI: 10.1016/J.Ydbio.2005.07.037  0.406
2005 Epstein JA, Parmacek MS. Recent advances in cardiac development with therapeutic implications for adult cardiovascular disease. Circulation. 112: 592-7. PMID 16043659 DOI: 10.1161/Circulationaha.104.479857  0.368
2005 Li J, Zhu X, Chen M, Cheng L, Zhou D, Lu MM, Du K, Epstein JA, Parmacek MS. Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proceedings of the National Academy of Sciences of the United States of America. 102: 8916-21. PMID 15951419 DOI: 10.1073/Pnas.0503741102  0.74
2005 Niu Z, Yu W, Zhang SX, Barron M, Belaguli NS, Schneider MD, Parmacek M, Nordheim A, Schwartz RJ. Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets. The Journal of Biological Chemistry. 280: 32531-8. PMID 15929941 DOI: 10.1074/Jbc.M501372200  0.493
2005 Lepore JJ, Cheng L, Min Lu M, Mericko PA, Morrisey EE, Parmacek MS. High-efficiency somatic mutagenesis in smooth muscle cells and cardiac myocytes in SM22alpha-Cre transgenic mice. Genesis (New York, N.Y. : 2000). 41: 179-84. PMID 15789423 DOI: 10.1002/Gene.20112  0.531
2005 Parmacek MS, Epstein JA. Pursuing cardiac progenitors: regeneration redux. Cell. 120: 295-8. PMID 15707888 DOI: 10.1016/J.Cell.2005.01.025  0.393
2005 Zhang SX, Garcia-Gras E, Wycuff DR, Marriot SJ, Kadeer N, Yu W, Olson EN, Garry DJ, Parmacek MS, Schwartz RJ. Identification of direct serum-response factor gene targets during Me2SO-induced P19 cardiac cell differentiation. The Journal of Biological Chemistry. 280: 19115-26. PMID 15699019 DOI: 10.1074/Jbc.M413793200  0.488
2005 Proweller A, Pear WS, Parmacek MS. Notch signaling represses myocardin-induced smooth muscle cell differentiation. The Journal of Biological Chemistry. 280: 8994-9004. PMID 15634680 DOI: 10.1074/Jbc.M413316200  0.521
2005 Lepore JJ, Cappola TP, Mericko PA, Morrisey EE, Parmacek MS. GATA-6 regulates genes promoting synthetic functions in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 309-14. PMID 15591218 DOI: 10.1161/01.Atv.0000152725.76020.3C  0.509
2005 Barron MR, Belaguli NS, Zhang SX, Trinh M, Iyer D, Merlo X, Lough JW, Parmacek MS, Bruneau BG, Schwartz RJ. Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes. The Journal of Biological Chemistry. 280: 11816-28. PMID 15591049 DOI: 10.1074/Jbc.M412408200  0.481
2004 Parmacek MS, Solaro RJ. Biology of the troponin complex in cardiac myocytes. Progress in Cardiovascular Diseases. 47: 159-76. PMID 15736582 DOI: 10.1016/J.Pcad.2004.07.003  0.423
2004 Ding R, Darland DC, Parmacek MS, D'Amore PA. Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation. Stem Cells and Development. 13: 509-20. PMID 15588508 DOI: 10.1089/Scd.2004.13.509  0.321
2004 Horwitz PA, Tsai EJ, Putt ME, Gilmore JM, Lepore JJ, Parmacek MS, Kao AC, Desai SS, Goldberg LR, Brozena SC, Jessup ML, Epstein JA, Cappola TP. Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression. Circulation. 110: 3815-21. PMID 15583081 DOI: 10.1161/01.Cir.0000150539.72783.Bf  0.331
2004 Parmacek MS. Myocardin--not quite MyoD. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1535-7. PMID 15345517 DOI: 10.1161/01.Atv.0000141044.03875.7F  0.53
2004 Zeidan A, Swärd K, Nordström I, Ekblad E, Zhang JC, Parmacek MS, Hellstrand P. Ablation of SM22alpha decreases contractility and actin contents of mouse vascular smooth muscle. Febs Letters. 562: 141-6. PMID 15044015 DOI: 10.1016/S0014-5793(04)00220-0  0.419
2004 Du KL, Chen M, Li J, Lepore JJ, Mericko P, Parmacek MS. Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells. The Journal of Biological Chemistry. 279: 17578-86. PMID 14970199 DOI: 10.1074/Jbc.M400961200  0.747
2003 Du KL, Ip HS, Li J, Chen M, Dandre F, Yu W, Lu MM, Owens GK, Parmacek MS. Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation. Molecular and Cellular Biology. 23: 2425-37. PMID 12640126 DOI: 10.1128/Mcb.23.7.2425-2437.2003  0.757
2002 Zhang JC, Helmke BP, Shum A, Du K, Yu WW, Lu MM, Davies PF, Parmacek MS. SM22beta encodes a lineage-restricted cytoskeletal protein with a unique developmentally regulated pattern of expression. Mechanisms of Development. 115: 161-6. PMID 12049783 DOI: 10.1016/S0925-4773(02)00088-6  0.73
2001 Strobeck M, Kim S, Zhang JC, Clendenin C, Du KL, Parmacek MS. Binding of serum response factor to CArG box sequences is necessary but not sufficient to restrict gene expression to arterial smooth muscle cells. The Journal of Biological Chemistry. 276: 16418-24. PMID 11279108 DOI: 10.1074/Jbc.M100631200  0.734
2001 Parmacek MS. Transcriptional programs regulating vascular smooth muscle cell development and differentiation. Current Topics in Developmental Biology. 51: 69-89. PMID 11236716 DOI: 10.1016/S0070-2153(01)51002-9  0.54
2001 Zhang JC, Kim S, Helmke BP, Yu WW, Du KL, Lu MM, Strobeck M, Yu Q, Parmacek MS. Analysis of SM22alpha-deficient mice reveals unanticipated insights into smooth muscle cell differentiation and function. Molecular and Cellular Biology. 21: 1336-44. PMID 11158319 DOI: 10.1128/Mcb.2001.21.4.1336-1344.2001  0.744
2000 Aoki K, Akyürek LM, San H, Leung K, Parmacek MS, Nabel EG, Nabel GJ. Restricted expression of an adenoviral vector encoding Fas ligand (CD95L) enhances safety for cancer gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 555-65. PMID 10933980 DOI: 10.1006/Mthe.2000.0076  0.412
2000 Akyürek LM, Yang Z, Aoki K, San H, Nabel GJ, Parmacek MS, Nabel EG. SM22α Promoter Targets Gene Expression to Vascular Smooth Muscle Cells In Vitro and In Vivo Molecular Medicine. 6: 983-991. DOI: 10.1007/Bf03401832  0.477
1998 Morrisey EE, Tang Z, Sigrist K, Lu MM, Jiang F, Ip HS, Parmacek MS. GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo Genes and Development. 12: 3579-3590. PMID 9832509 DOI: 10.1101/Gad.12.22.3579  0.519
1997 Kim S, Lin H, Barr E, Chu L, Leiden JM, Parmacek MS. Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo. The Journal of Clinical Investigation. 100: 1006-14. PMID 9276717 DOI: 10.1172/Jci119611  0.507
1997 Kuo CT, Morrisey EE, Anandappa R, Sigrist K, Lu MM, Parmacek MS, Soudais C, Leiden JM. GATA4 transcription factor is required for ventral morphogenesis and heart tube formation. Genes & Development. 11: 1048-60. PMID 9136932 DOI: 10.1101/Gad.11.8.1048  0.448
1992 Parmacek MS, Vora AJ, Shen T, Barr E, Jung F, Leiden JM. Identification and characterization of a cardiac-specific transcriptional regulatory element in the slow/cardiac troponin C gene. Molecular and Cellular Biology. 12: 1967-76. PMID 1569934 DOI: 10.1128/Mcb.12.5.1967  0.515
1989 Parmacek MS, Karpinski BA, Gottesdiener KM, Thompson CB, Leiden JM. Structure, expression and regulation of the murine 4F2 heavy chain. Nucleic Acids Research. 17: 1915-31. PMID 2928113 DOI: 10.1093/Nar/17.5.1915  0.414
1989 Coleman PS, Parmacek MS, Lesch M, Samarel AM. Protein synthesis and degradation during regression of thyroxine-induced cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 21: 911-25. PMID 2530358 DOI: 10.1016/0022-2828(89)90759-1  0.303
1987 Samarel AM, Parmacek MS, Magid NM, Decker RS, Lesch M. Protein synthesis and degradation during starvation-induced cardiac atrophy in rabbits. Circulation Research. 60: 933-41. PMID 3594760 DOI: 10.1161/01.Res.60.6.933  0.311
1987 PARMACEK M, LESCH M, DECKER R, SAMAREL A. Regulation of individual myofibrillar protein synthesis during thyroxine-induced left ventricular hypertrophy Journal of Molecular and Cellular Cardiology. 19: S28-S28. DOI: 10.1016/S0022-2828(87)80707-1  0.312
1986 Parmacek MS, Decker ML, Lesch M, Samarel AM, Decker RS. Lysosomal changes during thyroxine-induced left ventricular hypertrophy in rabbits. The American Journal of Physiology. 251: C737-47. PMID 2946237 DOI: 10.1152/Ajpcell.1986.251.5.C737  0.319
1986 PARMACEK M, LESCH M, DECKER R, SAMAREL A. Rabbit cardiac protein synthesis and degradation during thyroxine-induced cardiac hypertrophy Journal of Molecular and Cellular Cardiology. 18: 58-58. DOI: 10.1016/S0022-2828(86)80652-6  0.306
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