| Year |
Citation |
Score |
| 2022 |
Hunegnaw R, Honko AN, Wang L, Carr D, Murray T, Shi W, Nguyen L, Storm N, Dulan CNM, Foulds KE, Agans KN, Cross RW, Geisbert JB, Cheng C, Ploquin A, ... ... Nabel GJ, et al. A single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates. Science Translational Medicine. 14: eabq6364. PMID 36516269 DOI: 10.1126/scitranslmed.abq6364 |
0.316 |
|
| 2022 |
Wei CJ, Bu W, Nguyen LA, Batchelor JD, Kim J, Pittaluga S, Fuller JR, Nguyen H, Chou TH, Cohen JI, Nabel GJ. A bivalent Epstein-Barr virus vaccine induces neutralizing antibodies that block infection and confer immunity in humanized mice. Science Translational Medicine. 14: eabf3685. PMID 35507671 DOI: 10.1126/scitranslmed.abf3685 |
0.317 |
|
| 2022 |
Casazza JP, Cale EM, Narpala S, Yamshchikov GV, Coates EE, Hendel CS, Novik L, Holman LA, Widge AT, Apte P, Gordon I, Gaudinski MR, Conan-Cibotti M, Lin BC, Nason MC, ... ... Nabel GJ, et al. Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial. Nature Medicine. PMID 35411076 DOI: 10.1038/s41591-022-01762-x |
0.314 |
|
| 2020 |
Wei CJ, Crank MC, Shiver J, Graham BS, Mascola JR, Nabel GJ. Author Correction: Next-generation influenza vaccines: opportunities and challenges. Nature Reviews. Drug Discovery. 19: 427. PMID 32494049 DOI: 10.1038/S41573-020-0066-8 |
0.338 |
|
| 2020 |
Swanson KA, Rainho-Tomko JN, Williams ZP, Lanza L, Peredelchuk M, Kishko M, Pavot V, Alamares-Sapuay J, Adhikarla H, Gupta S, Chivukula S, Gallichan S, Zhang L, Jackson N, Yoon H, ... ... Nabel GJ, et al. A respiratory syncytial virus (RSV) F protein nanoparticle vaccine focuses antibody responses to a conserved neutralization domain. Science Immunology. 5. PMID 32358170 DOI: 10.1126/Sciimmunol.Aba6466 |
0.342 |
|
| 2020 |
Wei CJ, Crank MC, Shiver J, Graham BS, Mascola JR, Nabel GJ. Next-generation influenza vaccines: opportunities and challenges. Nature Reviews. Drug Discovery. PMID 32060419 DOI: 10.1038/S41573-019-0056-X |
0.411 |
|
| 2019 |
Elmer BM, Swanson KA, Bangari DS, Piepenhagen PA, Roberts E, Taksir T, Guo L, Obinu MC, Barneoud P, Ryan S, Zhang B, Pradier L, Yang ZY, Nabel GJ. Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer's disease. Plos One. 14: e0226245. PMID 31887144 DOI: 10.1371/Journal.Pone.0226245 |
0.326 |
|
| 2019 |
Rudicell RS, Garinot M, Kanekiyo M, Kamp HD, Swanson K, Chou TH, Dai S, Bedel O, Simard D, Gillespie RA, Yang K, Reardon M, Avila LZ, Besev M, Dhal PK, ... ... Nabel GJ, et al. Comparison of adjuvants to optimize influenza neutralizing antibody responses. Vaccine. PMID 31493950 DOI: 10.1016/J.Vaccine.2019.08.030 |
0.383 |
|
| 2019 |
Ko SY, Akahata W, Yang ES, Kong WP, Burke CW, Honnold SP, Nichols DK, Huang YS, Schieber GL, Carlton K, DaSilva L, Traina-Dorge V, Vanlandingham DL, Tsybovsky Y, Stephens T, ... ... Nabel GJ, et al. A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates. Science Translational Medicine. 11. PMID 31092692 DOI: 10.1126/Scitranslmed.Aav3113 |
0.429 |
|
| 2019 |
Bu W, Joyce MG, Nguyen H, Banh DV, Aguilar F, Tariq Z, Yap ML, Tsujimura Y, Gillespie RA, Tsybovsky Y, Andrews SF, Narpala SR, McDermott AB, Rossmann MG, Yasutomi Y, ... Nabel GJ, et al. Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells. Immunity. PMID 30979688 DOI: 10.1016/J.Immuni.2019.03.010 |
0.433 |
|
| 2019 |
Nabel GJ, Shiver JW. All for one and one for all to fight flu. Nature. 565: 29-31. PMID 30573785 DOI: 10.1038/D41586-018-07654-W |
0.303 |
|
| 2018 |
Darricarrère N, Pougatcheva S, Duan X, Rudicell RS, Chou TH, DiNapoli J, Ross TM, Alefantis T, Vogel TU, Kleanthous H, Wei CJ, Nabel GJ. Development of a Pan-H1 Influenza Vaccine. Journal of Virology. PMID 30185594 DOI: 10.1128/Jvi.01349-18 |
0.387 |
|
| 2018 |
Wagenaar TR, Hotz C, Gieseke F, Cao H, Diekmann J, Diken M, Grunwitz C, Hebert A, Hsu K, Jordan M, Kariko K, Kreiter S, Kuhn AN, Levit M, Malkova N, ... ... Nabel G, et al. Abstract LB-130: Combinatorial treatment with intratumoral cytokine mRNAs results in high frequency of tumor rejection and development of anti-tumor immunity across a range of preclinical cancer models Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-130 |
0.307 |
|
| 2017 |
Xu L, Pegu A, Rao E, Doria-Rose N, Beninga J, McKee K, Lord DM, Wei RR, Deng G, Louder M, Schmidt SD, Mankoff Z, Wu L, Asokan M, Beil C, ... ... Nabel GJ, et al. Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques. Science (New York, N.Y.). PMID 28931639 DOI: 10.1126/Science.Aan8630 |
0.443 |
|
| 2017 |
Saunders KO, Nicely NI, Wiehe K, Bonsignori M, Meyerhoff RR, Parks R, Walkowicz WE, Aussedat B, Wu NR, Cai F, Vohra Y, Park PK, Eaton A, Go EP, Sutherland LL, ... ... Nabel GJ, et al. Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Reports. 18: 2175-2188. PMID 28249163 DOI: 10.1016/J.Celrep.2017.02.003 |
0.438 |
|
| 2016 |
Crank MC, Wilson EM, Novik L, Enama ME, Hendel CS, Gu W, Nason MC, Bailer RT, Nabel GJ, McDermott AB, Mascola JR, Koup RA, Ledgerwood JE, Graham BS. Safety and Immunogenicity of a rAd35-EnvA Prototype HIV-1 Vaccine in Combination with rAd5-EnvA in Healthy Adults (VRC 012). Plos One. 11: e0166393. PMID 27846256 DOI: 10.1371/Journal.Pone.0166393 |
0.424 |
|
| 2016 |
Villar RF, Patel J, Weaver GC, Kanekiyo M, Wheatley AK, Yassine HM, Costello CE, Chandler KB, McTamney PM, Nabel GJ, McDermott AB, Mascola JR, Carr SA, Lingwood D. Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation. Scientific Reports. 6: 36298. PMID 27796362 DOI: 10.1038/Srep36298 |
0.341 |
|
| 2016 |
Girard MP, Le-Grand R, Picot V, Longuet C, Nabel GJ. Report of the Cent Gardes HIV Vaccines Conference, Part 2: The cellular immune response. Fondation Mérieux Conference Center, Veyrier-du-Lac, France, 25-27 October 2015. Vaccine. PMID 27692524 DOI: 10.1016/j.vaccine.2016.09.034 |
0.315 |
|
| 2016 |
Girard MP, Le-Grand R, Picot V, Longuet C, Nabel GJ. Report of the Cent Gardes HIV Vaccines Conference. Part 1: The antibody response; Fondation Mérieux Conference Center, Veyrier-du-Lac, France, 25-27 October 2015. Vaccine. PMID 27216761 DOI: 10.1016/J.Vaccine.2016.05.024 |
0.428 |
|
| 2016 |
Weaver GC, Villar RF, Kanekiyo M, Nabel GJ, Mascola JR, Lingwood D. In vitro reconstitution of B cell receptor-antigen interactions to evaluate potential vaccine candidates. Nature Protocols. 11: 193-213. PMID 26741406 DOI: 10.1038/Nprot.2016.009 |
0.392 |
|
| 2015 |
Cheng C, Wang L, Ko SY, Kong WP, Schmidt SD, Gall JG, Colloca S, Seder RA, Mascola JR, Nabel GJ. Combination recombinant simian or chimpanzee adenoviral vectors for vaccine development. Vaccine. PMID 26514419 DOI: 10.1016/J.Vaccine.2015.10.023 |
0.466 |
|
| 2015 |
Pegu A, Asokan M, Wu L, Wang K, Hataye J, Casazza JP, Guo X, Shi W, Georgiev I, Zhou T, Chen X, O'Dell S, Todd JP, Kwong PD, Rao SS, ... ... Nabel GJ, et al. Activation and lysis of human CD4 cells latently infected with HIV-1. Nature Communications. 6: 8447. PMID 26485194 DOI: 10.1038/Ncomms9447 |
0.412 |
|
| 2015 |
Asokan M, Rudicell RS, Louder M, McKee K, O'Dell S, Stewart-Jones G, Wang K, Xu L, Chen X, Choe M, Chuang G, Georgiev IS, Joyce MG, Kirys T, Ko S, ... ... Nabel GJ, et al. Bispecific antibodies targeting different epitopes on the HIV-1 envelope exhibit broad and potent neutralization. Journal of Virology. PMID 26446600 DOI: 10.1128/Jvi.02097-15 |
0.39 |
|
| 2015 |
Yassine HM, Boyington JC, McTamney PM, Wei CJ, Kanekiyo M, Kong WP, Gallagher JR, Wang L, Zhang Y, Joyce MG, Lingwood D, Moin SM, Andersen H, Okuno Y, Rao SS, ... ... Nabel GJ, et al. Hemagglutinin-stem nanoparticles generate heterosubtypic influenza protection. Nature Medicine. PMID 26301691 DOI: 10.1038/Nm.3927 |
0.354 |
|
| 2015 |
Kanekiyo M, Bu W, Joyce MG, Meng G, Whittle JR, Baxa U, Yamamoto T, Narpala S, Todd JP, Rao SS, McDermott AB, Koup RA, Rossmann MG, Mascola JR, Graham BS, ... ... Nabel GJ, et al. Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site. Cell. 162: 1090-100. PMID 26279189 DOI: 10.1016/J.Cell.2015.07.043 |
0.422 |
|
| 2015 |
Williams WB, Liao HX, Moody MA, Kepler TB, Alam SM, Gao F, Wiehe K, Trama AM, Jones K, Zhang R, Song H, Marshall DJ, Whitesides JF, Sawatzki K, Hua A, ... ... Nabel GJ, et al. HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. Science (New York, N.Y.). 349: aab1253. PMID 26229114 DOI: 10.1126/Science.Aab1253 |
0.452 |
|
| 2015 |
Girard MP, Picot V, Longuet C, Nabel GJ. Report of the 2014 Cent Gardes HIV Vaccine Conference-Part 2: Cell-mediated immunity, mucosal protection, and clinical trials: Fondation Mérieux Conference Center, Veyrier du Lac, France, 5-7 October, 2014. Vaccine. 33: 4051-5. PMID 26143614 DOI: 10.1016/J.Vaccine.2015.06.074 |
0.474 |
|
| 2015 |
Wheatley AK, Whittle JR, Lingwood D, Kanekiyo M, Yassine HM, Ma SS, Narpala SR, Prabhakaran MS, Matus-Nicodemos RA, Bailer RT, Nabel GJ, Graham BS, Ledgerwood JE, Koup RA, McDermott AB. H5N1 Vaccine-Elicited Memory B Cells Are Genetically Constrained by the IGHV Locus in the Recognition of a Neutralizing Epitope in the Hemagglutinin Stem. Journal of Immunology (Baltimore, Md. : 1950). 195: 602-10. PMID 26078272 DOI: 10.4049/Jimmunol.1402835 |
0.385 |
|
| 2015 |
Saunders KO, Wang L, Joyce MG, Yang ZY, Balazs AB, Cheng C, Ko SY, Kong WP, Rudicell RS, Georgiev IS, Duan L, Foulds KE, Donaldson M, Xu L, Schmidt SD, ... ... Nabel GJ, et al. Broadly neutralizing human immunodeficiency virus type 1 antibody gene transfer protects non-human primates from mucosal simian-human immunodeficiency virus infection. Journal of Virology. PMID 26041300 DOI: 10.1128/Jvi.00908-15 |
0.443 |
|
| 2015 |
Crank MC, Gordon IJ, Yamshchikov GV, Sitar S, Hu Z, Enama ME, Holman LA, Bailer RT, Pearce MB, Koup RA, Mascola JR, Nabel GJ, Tumpey TM, Schwartz RM, Graham BS, et al. Phase 1 study of pandemic H1 DNA vaccine in healthy adults. Plos One. 10: e0123969. PMID 25884189 DOI: 10.1371/Journal.Pone.0123969 |
0.387 |
|
| 2015 |
Saunders KO, Pegu A, Georgiev IS, Zeng M, Joyce MG, Yang ZY, Ko SY, Chen X, Schmidt SD, Haase AT, Todd JP, Bao S, Kwong PD, Rao SS, Mascola JR, ... Nabel GJ, et al. Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection. Journal of Virology. 89: 5895-903. PMID 25787288 DOI: 10.1128/Jvi.00210-15 |
0.407 |
|
| 2015 |
Girard MP, Picot V, Longuet C, Nabel GJ. Report of the 2014 Cent Gardes HIV Vaccine Conference - Part 1: Neutralizing Antibodies; Fondation Mérieux Conference Center, Veyrier du Lac, France, 5-7 October 2014. Vaccine. 33: 3605-8. PMID 25769208 DOI: 10.1016/J.Vaccine.2015.03.004 |
0.473 |
|
| 2015 |
Kibuuka H, Berkowitz NM, Millard M, Enama ME, Tindikahwa A, Sekiziyivu AB, Costner P, Sitar S, Glover D, Hu Z, Joshi G, Stanley D, Kunchai M, Eller LA, Bailer RT, ... ... Nabel GJ, et al. Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial. Lancet (London, England). 385: 1545-54. PMID 25540891 DOI: 10.1016/S0140-6736(14)62385-0 |
0.404 |
|
| 2015 |
Roychoudhuri R, Lefebvre F, Honda M, Pan L, Ji Y, Klebanoff CA, Nichols CN, Fourati S, Hegazy AN, Goulet JP, Gattinoni L, Nabel GJ, Gilliet M, Cameron M, Restifo NP, et al. Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation. Vaccine. 33: 914-23. PMID 25446821 DOI: 10.1016/J.Vaccine.2014.10.007 |
0.383 |
|
| 2015 |
Sarwar UN, Costner P, Enama ME, Berkowitz N, Hu Z, Hendel CS, Sitar S, Plummer S, Mulangu S, Bailer RT, Koup RA, Mascola JR, Nabel GJ, Sullivan NJ, Graham BS, et al. Safety and immunogenicity of DNA vaccines encoding Ebolavirus and Marburgvirus wild-type glycoproteins in a phase I clinical trial. The Journal of Infectious Diseases. 211: 549-57. PMID 25225676 DOI: 10.1093/Infdis/Jiu511 |
0.359 |
|
| 2015 |
Williams WB, Liao HX, Moody MA, Kepler TB, Alam SM, Gao F, Wiehe K, Trama AM, Jones K, Zhang R, Song H, Marshall DJ, Whitesides JF, Sawatzki K, Hua A, ... ... Nabel GJ, et al. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies Science. 349. DOI: 10.1126/science.aab1253 |
0.32 |
|
| 2014 |
Stanley DA, Honko AN, Asiedu C, Trefry JC, Lau-Kilby AW, Johnson JC, Hensley L, Ammendola V, Abbate A, Grazioli F, Foulds KE, Cheng C, Wang L, Donaldson MM, Colloca S, ... ... Nabel GJ, et al. Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge. Nature Medicine. 20: 1126-9. PMID 25194571 DOI: 10.1038/Nm.3702 |
0.396 |
|
| 2014 |
Shingai M, Donau OK, Plishka RJ, Buckler-White A, Mascola JR, Nabel GJ, Nason MC, Montefiori D, Moldt B, Poignard P, Diskin R, Bjorkman PJ, Eckhaus MA, Klein F, Mouquet H, et al. Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques. The Journal of Experimental Medicine. 211: 2061-74. PMID 25155019 DOI: 10.1084/Jem.20132494 |
0.452 |
|
| 2014 |
Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, ... ... Nabel GJ, et al. Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. Journal of Virology. 88: 12669-82. PMID 25142607 DOI: 10.1128/Jvi.02213-14 |
0.42 |
|
| 2014 |
Chang LJ, Dowd KA, Mendoza FH, Saunders JG, Sitar S, Plummer SH, Yamshchikov G, Sarwar UN, Hu Z, Enama ME, Bailer RT, Koup RA, Schwartz RM, Akahata W, Nabel GJ, et al. Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial. Lancet. 384: 2046-52. PMID 25132507 DOI: 10.1016/S0140-6736(14)61185-5 |
0.371 |
|
| 2014 |
Li SS, Gilbert PB, Tomaras GD, Kijak G, Ferrari G, Thomas R, Pyo CW, Zolla-Pazner S, Montefiori D, Liao HX, Nabel G, Pinter A, Evans DT, Gottardo R, Dai JY, et al. FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial. The Journal of Clinical Investigation. 124: 3879-90. PMID 25105367 DOI: 10.1172/Jci75539 |
0.401 |
|
| 2014 |
Pegu A, Yang ZY, Boyington JC, Wu L, Ko SY, Schmidt SD, McKee K, Kong WP, Shi W, Chen X, Todd JP, Letvin NL, Huang J, Nason MC, Hoxie JA, ... ... Nabel GJ, et al. Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Science Translational Medicine. 6: 243ra88. PMID 24990883 DOI: 10.1126/Scitranslmed.3008992 |
0.403 |
|
| 2014 |
Yates NL, Liao HX, Fong Y, deCamp A, Vandergrift NA, Williams WT, Alam SM, Ferrari G, Yang ZY, Seaton KE, Berman PW, Alpert MD, Evans DT, O'Connell RJ, Francis D, ... ... Nabel GJ, et al. Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination. Science Translational Medicine. 6: 228ra39. PMID 24648342 DOI: 10.1126/Scitranslmed.3007730 |
0.34 |
|
| 2014 |
Enama ME, Ledgerwood JE, Novik L, Nason MC, Gordon IJ, Holman L, Bailer RT, Roederer M, Koup RA, Mascola JR, Nabel GJ, Graham BS. Phase I randomized clinical trial of VRC DNA and rAd5 HIV-1 vaccine delivery by intramuscular (i.m.), subcutaneous (s.c.) and intradermal (i.d.) administration (VRC 011). Plos One. 9: e91366. PMID 24621858 DOI: 10.1371/Journal.Pone.0091366 |
0.356 |
|
| 2014 |
Zolla-Pazner S, deCamp A, Gilbert PB, Williams C, Yates NL, Williams WT, Howington R, Fong Y, Morris DE, Soderberg KA, Irene C, Reichman C, Pinter A, Parks R, Pitisuttithum P, ... ... Nabel GJ, et al. Vaccine-induced IgG antibodies to V1V2 regions of multiple HIV-1 subtypes correlate with decreased risk of HIV-1 infection. Plos One. 9: e87572. PMID 24504509 DOI: 10.1371/Journal.Pone.0087572 |
0.433 |
|
| 2014 |
Whittle JR, Wheatley AK, Wu L, Lingwood D, Kanekiyo M, Ma SS, Narpala SR, Yassine HM, Frank GM, Yewdell JW, Ledgerwood JE, Wei CJ, McDermott AB, Graham BS, Koup RA, ... Nabel GJ, et al. Flow cytometry reveals that H5N1 vaccination elicits cross-reactive stem-directed antibodies from multiple Ig heavy-chain lineages. Journal of Virology. 88: 4047-57. PMID 24501410 DOI: 10.1128/Jvi.03422-13 |
0.389 |
|
| 2014 |
Nabel GJ, Yang ZY, Nabel EG. Methods for liposome-mediated gene transfer to tumor cells in vivo. Methods in Molecular Medicine. 7: 297-305. PMID 24493435 DOI: 10.1385/0-89603-484-4:297 |
0.323 |
|
| 2014 |
Nabel EG, Yang ZY, San H, Carr DP, Nabel GJ. Methods for liposome-mediated gene transfer to the arterial wall. Methods in Molecular Medicine. 7: 127-33. PMID 24493422 DOI: 10.1385/0-89603-484-4:127 |
0.303 |
|
| 2014 |
Georgiev IS, Rudicell RS, Saunders KO, Shi W, Kirys T, McKee K, O'Dell S, Chuang GY, Yang ZY, Ofek G, Connors M, Mascola JR, Nabel GJ, Kwong PD. Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline. Journal of Immunology (Baltimore, Md. : 1950). 192: 1100-6. PMID 24391217 DOI: 10.4049/Jimmunol.1302515 |
0.342 |
|
| 2014 |
Roederer M, Keele BF, Schmidt SD, Mason RD, Welles HC, Fischer W, Labranche C, Foulds KE, Louder MK, Yang ZY, Todd JP, Buzby AP, Mach LV, Shen L, Seaton KE, ... ... Nabel GJ, et al. Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV. Nature. 505: 502-8. PMID 24352234 DOI: 10.1038/Nature12893 |
0.381 |
|
| 2014 |
Haynes BF, Saunders KO, Kelsoe G, Mascola JR, Nabel GJ. The Cellular and Molecular Biology of HIV-1 Broadly Neutralizing Antibodies Molecular Biology of B Cells: Second Edition. 441-461. DOI: 10.1016/B978-0-12-397933-9.00024-2 |
0.359 |
|
| 2013 |
Cooper A, GarcÃa M, Petrovas C, Yamamoto T, Koup RA, Nabel GJ. HIV integration and T cell death: additional commentary. Retrovirology. 10: 150. PMID 24321564 DOI: 10.1186/1742-4690-10-150 |
0.326 |
|
| 2013 |
Hammer SM, Sobieszczyk ME, Janes H, Karuna ST, Mulligan MJ, Grove D, Koblin BA, Buchbinder SP, Keefer MC, Tomaras GD, Frahm N, Hural J, Anude C, Graham BS, Enama ME, ... ... Nabel GJ, et al. Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine. The New England Journal of Medicine. 369: 2083-92. PMID 24099601 DOI: 10.1056/Nejmoa1310566 |
0.322 |
|
| 2013 |
Kwong PD, Mascola JR, Nabel GJ. Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning. Nature Reviews. Immunology. 13: 693-701. PMID 23969737 DOI: 10.1038/Nri3516 |
0.432 |
|
| 2013 |
Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Do Kwon Y, Longo NS, Louder MK, Luongo T, McKee K, ... ... Nabel GJ, et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity. 39: 245-58. PMID 23911655 DOI: 10.1016/J.Immuni.2013.04.012 |
0.383 |
|
| 2013 |
Yewdell JW, Spiro DJ, Golding H, Quill H, Mittelman A, Nabel GJ. Getting to the heart of influenza. Science Translational Medicine. 5: 191ed8. PMID 23803701 DOI: 10.1126/Scitranslmed.3006735 |
0.364 |
|
| 2013 |
Cooper A, GarcÃa M, Petrovas C, Yamamoto T, Koup RA, Nabel GJ. HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration. Nature. 498: 376-9. PMID 23739328 DOI: 10.1038/Nature12274 |
0.401 |
|
| 2013 |
Koff WC, Burton DR, Johnson PR, Walker BD, King CR, Nabel GJ, Ahmed R, Bhan MK, Plotkin SA. Accelerating next-generation vaccine development for global disease prevention. Science (New York, N.Y.). 340: 1232910. PMID 23723240 DOI: 10.1126/Science.1232910 |
0.378 |
|
| 2013 |
Pancera M, Shahzad-Ul-Hussan S, Doria-Rose NA, McLellan JS, Bailer RT, Dai K, Loesgen S, Louder MK, Staupe RP, Yang Y, Zhang B, Parks R, Eudailey J, Lloyd KE, Blinn J, ... ... Nabel GJ, et al. Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16. Nature Structural & Molecular Biology. 20: 804-13. PMID 23708607 DOI: 10.1038/Nsmb.2600 |
0.361 |
|
| 2013 |
Kanekiyo M, Wei CJ, Yassine HM, McTamney PM, Boyington JC, Whittle JR, Rao SS, Kong WP, Wang L, Nabel GJ. Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodies. Nature. 499: 102-6. PMID 23698367 DOI: 10.1038/Nature12202 |
0.401 |
|
| 2013 |
Pal P, Dowd KA, Brien JD, Edeling MA, Gorlatov S, Johnson S, Lee I, Akahata W, Nabel GJ, Richter MK, Smit JM, Fremont DH, Pierson TC, Heise MT, Diamond MS. Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus. Plos Pathogens. 9: e1003312. PMID 23637602 DOI: 10.1371/Journal.Ppat.1003312 |
0.365 |
|
| 2013 |
Ledgerwood JE, Zephir K, Hu Z, Wei CJ, Chang L, Enama ME, Hendel CS, Sitar S, Bailer RT, Koup RA, Mascola JR, Nabel GJ, Graham BS. Prime-boost interval matters: a randomized phase 1 study to identify the minimum interval necessary to observe the H5 DNA influenza vaccine priming effect. The Journal of Infectious Diseases. 208: 418-22. PMID 23633407 DOI: 10.1093/Infdis/Jit180 |
0.371 |
|
| 2013 |
Girard MP, Picot V, Longuet C, Nabel GJ. Report of the Cent Gardes HIV Vaccine Conference: The B-cell response to HIV. Part 2: Non-neutralizing antibodies: Fondation Mérieux Conference Center, Veyrier du Lac, France 5-7 November 2012. Vaccine. 31: 2984-7. PMID 23602538 DOI: 10.1016/J.Vaccine.2013.02.067 |
0.467 |
|
| 2013 |
Koff WC, Russell ND, Walport M, Feinberg MB, Shiver JW, Karim SA, Walker BD, McGlynn MG, Nweneka CV, Nabel GJ. Accelerating the development of a safe and effective HIV vaccine: HIV vaccine case study for the Decade of Vaccines. Vaccine. 31: B204-8. PMID 23598483 DOI: 10.1016/J.Vaccine.2012.10.115 |
0.449 |
|
| 2013 |
Cohen JI, Mocarski ES, Raab-Traub N, Corey L, Nabel GJ. The need and challenges for development of an Epstein-Barr virus vaccine. Vaccine. 31: B194-6. PMID 23598481 DOI: 10.1016/J.Vaccine.2012.09.041 |
0.403 |
|
| 2013 |
Graham BS, Enama ME, Nason MC, Gordon IJ, Peel SA, Ledgerwood JE, Plummer SA, Mascola JR, Bailer RT, Roederer M, Koup RA, Nabel GJ. DNA vaccine delivered by a needle-free injection device improves potency of priming for antibody and CD8+ T-cell responses after rAd5 boost in a randomized clinical trial. Plos One. 8: e59340. PMID 23577062 DOI: 10.1371/Journal.Pone.0059340 |
0.351 |
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| 2013 |
Girard MP, Picot V, Longuet C, Nabel GJ. Report of the Cent Gardes HIV Vaccine Conference: The B-cell Response to HIV. Part 1: Broadly Neutralizing Antibodies Fondation Mérieux Conference Center, Veyrier du Lac, France, 5-7 November 2012. Vaccine. 31: 2979-83. PMID 23499518 DOI: 10.1016/J.Vaccine.2013.02.068 |
0.48 |
|
| 2013 |
Quinn KM, Da Costa A, Yamamoto A, Berry D, Lindsay RW, Darrah PA, Wang L, Cheng C, Kong WP, Gall JG, Nicosia A, Folgori A, Colloca S, Cortese R, Gostick E, ... ... Nabel GJ, et al. Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization. Journal of Immunology (Baltimore, Md. : 1950). 190: 2720-35. PMID 23390298 DOI: 10.4049/Jimmunol.1202861 |
0.351 |
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| 2013 |
Nabel GJ. Designing tomorrow's vaccines. The New England Journal of Medicine. 368: 551-60. PMID 23388006 DOI: 10.1056/Nejmra1204186 |
0.342 |
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| 2013 |
Liao HX, Bonsignori M, Alam SM, McLellan JS, Tomaras GD, Moody MA, Kozink DM, Hwang KK, Chen X, Tsao CY, Liu P, Lu X, Parks RJ, Montefiori DC, Ferrari G, ... ... Nabel GJ, et al. Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. Immunity. 38: 176-86. PMID 23313589 DOI: 10.1016/J.Immuni.2012.11.011 |
0.461 |
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| 2013 |
Joyce MG, Kanekiyo M, Xu L, Biertümpfel C, Boyington JC, Moquin S, Shi W, Wu X, Yang Y, Yang ZY, Zhang B, Zheng A, Zhou T, Zhu J, Mascola JR, ... ... Nabel GJ, et al. Outer domain of HIV-1 gp120: antigenic optimization, structural malleability, and crystal structure with antibody VRC-PG04. Journal of Virology. 87: 2294-306. PMID 23236069 DOI: 10.1128/Jvi.02717-12 |
0.365 |
|
| 2013 |
Sun S, Xiang Y, Akahata W, Holdaway H, Pal P, Zhang X, Diamond MS, Nabel GJ, Rossmann MG. Author response: Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization Elife. DOI: 10.7554/Elife.00435.020 |
0.306 |
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| 2012 |
Nabel GJ. Rational design of vaccines for AIDS and influenza. Transactions of the American Clinical and Climatological Association. 123: 9-15; discussion 15-. PMID 23303965 |
0.34 |
|
| 2012 |
Fischer W, Apetrei C, Santiago ML, Li Y, Gautam R, Pandrea I, Shaw GM, Hahn BH, Letvin NL, Nabel GJ, Korber BT. Distinct evolutionary pressures underlie diversity in simian immunodeficiency virus and human immunodeficiency virus lineages. Journal of Virology. 86: 13217-31. PMID 23055550 DOI: 10.1128/Jvi.01862-12 |
0.447 |
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| 2012 |
Ledgerwood JE, Hu Z, Gordon IJ, Yamshchikov G, Enama ME, Plummer S, Bailer R, Pearce MB, Tumpey TM, Koup RA, Mascola JR, Nabel GJ, Graham BS. Influenza virus h5 DNA vaccination is immunogenic by intramuscular and intradermal routes in humans. Clinical and Vaccine Immunology : Cvi. 19: 1792-7. PMID 22956656 DOI: 10.1128/Cvi.05663-11 |
0.378 |
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| 2012 |
Lingwood D, McTamney PM, Yassine HM, Whittle JR, Guo X, Boyington JC, Wei CJ, Nabel GJ. Structural and genetic basis for development of broadly neutralizing influenza antibodies. Nature. 489: 566-70. PMID 22932267 DOI: 10.1038/Nature11371 |
0.413 |
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| 2012 |
Wei CJ, Yassine HM, McTamney PM, Gall JG, Whittle JR, Boyington JC, Nabel GJ. Elicitation of broadly neutralizing influenza antibodies in animals with previous influenza exposure. Science Translational Medicine. 4: 147ra114. PMID 22896678 DOI: 10.1126/Scitranslmed.3004273 |
0.423 |
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| 2012 |
Kwong PD, Mascola JR, Nabel GJ. The changing face of HIV vaccine research. Journal of the International Aids Society. 15: 17407. PMID 22789610 DOI: 10.7448/Ias.15.2.17407 |
0.449 |
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| 2012 |
Nabel GJ, Wolinsky SM, Haynes BF. Retrospective. Norman L. Letvin (1949-2012). Science (New York, N.Y.). 336: 1653. PMID 22745414 DOI: 10.1126/Science.1225947 |
0.387 |
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| 2012 |
Saunders KO, Rudicell RS, Nabel GJ. The design and evaluation of HIV-1 vaccines. Aids (London, England). 26: 1293-302. PMID 22706011 DOI: 10.1097/Qad.0B013E32835474D2 |
0.439 |
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| 2012 |
Smalls-Mantey A, Doria-Rose N, Klein R, Patamawenu A, Migueles SA, Ko SY, Hallahan CW, Wong H, Liu B, You L, Scheid J, Kappes JC, Ochsenbauer C, Nabel GJ, Mascola JR, et al. Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding. Journal of Virology. 86: 8672-80. PMID 22674985 DOI: 10.1128/Jvi.00287-12 |
0.432 |
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| 2012 |
O'Donnell CD, Wright A, Vogel LN, Wei CJ, Nabel GJ, Subbarao K. Effect of priming with H1N1 influenza viruses of variable antigenic distances on challenge with 2009 pandemic H1N1 virus. Journal of Virology. 86: 8625-33. PMID 22674976 DOI: 10.1128/Jvi.00147-12 |
0.371 |
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| 2012 |
Akahata W, Nabel GJ. A specific domain of the Chikungunya virus E2 protein regulates particle formation in human cells: implications for alphavirus vaccine design. Journal of Virology. 86: 8879-83. PMID 22647698 DOI: 10.1128/Jvi.00370-12 |
0.306 |
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| 2012 |
Flatz L, Cheng C, Wang L, Foulds KE, Ko SY, Kong WP, Roychoudhuri R, Shi W, Bao S, Todd JP, Asmal M, Shen L, Donaldson M, Schmidt SD, Gall JG, ... ... Nabel GJ, et al. Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates. Journal of Virology. 86: 7760-70. PMID 22593152 DOI: 10.1128/Jvi.00599-12 |
0.479 |
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| 2012 |
Lynch RM, Tran L, Louder MK, Schmidt SD, Cohen M, Dersimonian R, Euler Z, Gray ES, Abdool Karim S, Kirchherr J, Montefiori DC, Sibeko S, Soderberg K, Tomaras G, ... ... Nabel GJ, et al. The development of CD4 binding site antibodies during HIV-1 infection. Journal of Virology. 86: 7588-95. PMID 22573869 DOI: 10.1128/Jvi.00734-12 |
0.39 |
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| 2012 |
Yeh WW, Brassard LM, Miller CA, Basavapathruni A, Zhang J, Rao SS, Nabel GJ, Mascola JR, Letvin NL, Seaman MS. Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeys. Journal of Virology. 86: 7052-9. PMID 22532675 DOI: 10.1128/Jvi.00107-12 |
0.443 |
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| 2012 |
Santra S, Muldoon M, Watson S, Buzby A, Balachandran H, Carlson KR, Mach L, Kong WP, McKee K, Yang ZY, Rao SS, Mascola JR, Nabel GJ, Korber BT, Letvin NL. Breadth of cellular and humoral immune responses elicited in rhesus monkeys by multi-valent mosaic and consensus immunogens. Virology. 428: 121-7. PMID 22521913 DOI: 10.1016/J.Virol.2012.03.012 |
0.464 |
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| 2012 |
Cheng C, Wang L, Wang L, Gall JG, Nason M, Schwartz RM, McElrath MJ, DeRosa SC, Hural J, Corey L, Buchbinder SP, Nabel GJ. Decreased pre-existing Ad5 capsid and Ad35 neutralizing antibodies increase HIV-1 infection risk in the Step trial independent of vaccination. Plos One. 7: e33969. PMID 22496775 DOI: 10.1371/Journal.Pone.0033969 |
0.395 |
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| 2012 |
Ault A, Zajac AM, Kong WP, Gorres JP, Royals M, Wei CJ, Bao S, Yang ZY, Reedy SE, Sturgill TL, Page AE, Donofrio-Newman J, Adams AA, Balasuriya UB, Horohov DW, ... ... Nabel GJ, et al. Immunogenicity and clinical protection against equine influenza by DNA vaccination of ponies. Vaccine. 30: 3965-74. PMID 22449425 DOI: 10.1016/J.Vaccine.2012.03.026 |
0.416 |
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| 2012 |
Yamamoto T, Johnson MJ, Price DA, Wolinsky DI, Almeida JR, Petrovas C, Nason M, Yeh WW, Shen L, Roederer M, Rao SS, McDermott AB, Lefebvre F, Nabel GJ, Haddad EK, et al. Virus inhibition activity of effector memory CD8(+) T cells determines simian immunodeficiency virus load in vaccinated monkeys after vaccine breakthrough infection. Journal of Virology. 86: 5877-84. PMID 22419810 DOI: 10.1128/Jvi.00315-12 |
0.465 |
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| 2012 |
García M, Cooper A, Shi W, Bornmann W, Carrion R, Kalman D, Nabel GJ. Productive replication of Ebola virus is regulated by the c-Abl1 tyrosine kinase. Science Translational Medicine. 4: 123ra24. PMID 22378924 DOI: 10.1126/Scitranslmed.3003500 |
0.332 |
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| 2012 |
Joyce M, Zhang B, Zhou T, Moquin S, Wu X, Louder M, Zhang Z, Georgiev I, Zhu J, Shapiro L, Mascola J, Nabel G, Kwong P. Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P68 |
0.392 |
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| 2012 |
Chuang G, Boyington J, Nabel G, Kwong P, Georgiev I. Transforming epitope-specific gp120 monomer-based probes into immunogens with N-linked glycan masking Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P318 |
0.356 |
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| 2012 |
Dai K, Boyington J, Shi W, Schmidt S, Georgiev I, Lingwood D, Kwong P, Mascola J, Yang Z, Nabel G. Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site. Retrovirology. 9: 23. DOI: 10.1186/1742-4690-9-S2-P23 |
0.339 |
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| 2012 |
Sastry M, Xu L, Bhattacharya S, Nabel G, Bewley C, Kwong P. NMR spectroscopy of HIV-1 gp120 outer domain Retrovirology. 9: 20. DOI: 10.1186/1742-4690-9-S2-P20 |
0.368 |
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| 2012 |
Rudicell R, Georgiev I, Yang Z, O'Dell S, Kwon Y, Zhu J, Wu X, Kwong P, Mascola J, Nabel G. Partial germline reversions can increase VRC07 potency and breadth Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-P101 |
0.317 |
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| 2012 |
Williams W, Jones K, Krambrink A, Grove D, Liu P, Yates N, Moody M, Ferrari G, Pollara J, Moodie Z, Morgan C, Liao H, Montefiori D, Ochsenbauer C, Kappes J, ... ... Nabel G, et al. Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O55 |
0.369 |
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| 2012 |
Zhang Z, Wu X, Longo N, Zhang B, Zhu J, NISC C, Mullikin J, Wu L, Nabel G, Connors M, Kwong P, Mascola J, Shapiro L. Deep sequencing with longitudinal sampling of a VRC01-like-antibody response in a chronically infected individual Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O36 |
0.351 |
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| 2012 |
Kwon Y, Georgiev I, O'Dell S, Shi W, Chuang G, Yang Y, Zhang B, Zhu J, Nabel G, Mascola J, Kwong P. Structure-guided modification and optimization of antibody VRC07 Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O34 |
0.375 |
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| 2012 |
Liao L, Bonsignori M, Hwang K, Moody A, Park R, Crawford S, Chen H, Jeffries T, Cooper M, Lu X, De R, Karasavvas N, Rerks-Ngarm S, Nitayaphan S, Kaewkungwal J, ... ... Nabel G, et al. Design of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2 Retrovirology. 9. DOI: 10.1186/1742-4690-9-S2-O31 |
0.307 |
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| 2012 |
Nabel GJ, Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, OʼDell S, Louder MK, et al. 126 Broadly Neutralizing HIV Abs Jaids Journal of Acquired Immune Deficiency Syndromes. 59: 52. DOI: 10.1097/01.Qai.0000413745.31643.03 |
0.341 |
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| 2011 |
Kwong PD, Mascola JR, Nabel GJ. Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1. Cold Spring Harbor Perspectives in Medicine. 1: a007278. PMID 22229123 DOI: 10.1101/Cshperspect.A007278 |
0.438 |
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| 2011 |
McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, ... ... Nabel GJ, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature. 480: 336-43. PMID 22113616 DOI: 10.1038/Nature10696 |
0.337 |
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| 2011 |
Cohen JI, Fauci AS, Varmus H, Nabel GJ. Epstein-Barr virus: an important vaccine target for cancer prevention. Science Translational Medicine. 3: 107fs7. PMID 22049067 DOI: 10.1126/Scitranslmed.3002878 |
0.366 |
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| 2011 |
Ledgerwood JE, Wei CJ, Hu Z, Gordon IJ, Enama ME, Hendel CS, McTamney PM, Pearce MB, Yassine HM, Boyington JC, Bailer R, Tumpey TM, Koup RA, Mascola JR, Nabel GJ, et al. DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials. The Lancet. Infectious Diseases. 11: 916-24. PMID 21975270 DOI: 10.1016/S1473-3099(11)70240-7 |
0.4 |
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| 2011 |
Gorres JP, Lager KM, Kong WP, Royals M, Todd JP, Vincent AL, Wei CJ, Loving CL, Zanella EL, Janke B, Kehrli ME, Nabel GJ, Rao SS. DNA vaccination elicits protective immune responses against pandemic and classic swine influenza viruses in pigs. Clinical and Vaccine Immunology : Cvi. 18: 1987-95. PMID 21918118 DOI: 10.1128/Cvi.05171-11 |
0.417 |
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| 2011 |
Nabel GJ, Kwong PD, Mascola JR. Progress in the rational design of an AIDS vaccine. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2759-65. PMID 21893538 DOI: 10.1098/Rstb.2011.0096 |
0.449 |
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| 2011 |
Churchyard GJ, Morgan C, Adams E, Hural J, Graham BS, Moodie Z, Grove D, Gray G, Bekker LG, McElrath MJ, Tomaras GD, Goepfert P, Kalams S, Baden LR, Lally M, ... ... Nabel GJ, et al. A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204). Plos One. 6: e21225. PMID 21857901 DOI: 10.1371/Journal.Pone.0021225 |
0.396 |
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| 2011 |
Sullivan NJ, Hensley L, Asiedu C, Geisbert TW, Stanley D, Johnson J, Honko A, Olinger G, Bailey M, Geisbert JB, Reimann KA, Bao S, Rao S, Roederer M, Jahrling PB, ... ... Nabel GJ, et al. CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates. Nature Medicine. 17: 1128-31. PMID 21857654 DOI: 10.1038/Nm.2447 |
0.456 |
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| 2011 |
De Rosa SC, Thomas EP, Bui J, Huang Y, deCamp A, Morgan C, Kalams SA, Tomaras GD, Akondy R, Ahmed R, Lau CY, Graham BS, Nabel GJ, McElrath MJ. HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable. Journal of Immunology (Baltimore, Md. : 1950). 187: 3391-401. PMID 21844392 DOI: 10.4049/Jimmunol.1101421 |
0.432 |
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| 2011 |
Bonsignori M, Hwang KK, Chen X, Tsao CY, Morris L, Gray E, Marshall DJ, Crump JA, Kapiga SH, Sam NE, Sinangil F, Pancera M, Yongping Y, Zhang B, Zhu J, ... ... Nabel GJ, et al. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. Journal of Virology. 85: 9998-10009. PMID 21795340 DOI: 10.1128/Jvi.05045-11 |
0.375 |
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| 2011 |
Yeh WW, Rao SS, Lim SY, Zhang J, Hraber PT, Brassard LM, Luedemann C, Todd JP, Dodson A, Shen L, Buzby AP, Whitney JB, Korber BT, Nabel GJ, Mascola JR, et al. The TRIM5 gene modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys. Journal of Virology. 85: 10389-98. PMID 21775457 DOI: 10.1128/Jvi.00854-11 |
0.391 |
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| 2011 |
Letvin NL, Rao SS, Montefiori DC, Seaman MS, Sun Y, Lim SY, Yeh WW, Asmal M, Gelman RS, Shen L, Whitney JB, Seoighe C, Lacerda M, Keating S, Norris PJ, ... ... Nabel GJ, et al. Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys. Science Translational Medicine. 3: 81ra36. PMID 21543722 DOI: 10.1126/Scitranslmed.3002351 |
0.464 |
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| 2011 |
Corey L, Nabel GJ, Dieffenbach C, Gilbert P, Haynes BF, Johnston M, Kublin J, Lane HC, Pantaleo G, Picker LJ, Fauci AS. HIV-1 vaccines and adaptive trial designs. Science Translational Medicine. 3: 79ps13. PMID 21508308 DOI: 10.1126/Scitranslmed.3001863 |
0.444 |
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| 2011 |
Flatz L, Roychoudhuri R, Honda M, Filali-Mouhim A, Goulet JP, Kettaf N, Lin M, Roederer M, Haddad EK, Sékaly RP, Nabel GJ. Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines. Proceedings of the National Academy of Sciences of the United States of America. 108: 5724-9. PMID 21422297 DOI: 10.1073/Pnas.1013084108 |
0.43 |
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| 2011 |
Ledgerwood JE, Pierson TC, Hubka SA, Desai N, Rucker S, Gordon IJ, Enama ME, Nelson S, Nason M, Gu W, Bundrant N, Koup RA, Bailer RT, Mascola JR, Nabel GJ, et al. A West Nile virus DNA vaccine utilizing a modified promoter induces neutralizing antibody in younger and older healthy adults in a phase I clinical trial. The Journal of Infectious Diseases. 203: 1396-404. PMID 21398392 DOI: 10.1093/Infdis/Jir054 |
0.4 |
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| 2011 |
Nabel GJ, Wei CJ, Ledgerwood JE. Vaccinate for the next H2N2 pandemic now. Nature. 471: 157-8. PMID 21390107 DOI: 10.1038/471157A |
0.37 |
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| 2011 |
Whitney JB, Hraber PT, Luedemann C, Giorgi EE, Daniels MG, Bhattacharya T, Rao SS, Mascola JR, Nabel GJ, Korber BT, Letvin NL. Genital tract sequestration of SIV following acute infection. Plos Pathogens. 7: e1001293. PMID 21379569 DOI: 10.1371/Journal.Ppat.1001293 |
0.358 |
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| 2011 |
Yeh W, Rao S, Lim S, Zhang J, Hraber P, Brassard L, Luedemann C, Todd JP, Dodson A, Shen L, Buzby A, Whitney J, Korber B, Nabel G, Mascola J, et al. TRIM5 modulates penile mucosal acquisition of simian immunodeficiency virus in rhesus monkeys F1000research. 2. DOI: 10.7490/F1000Research.1089571.1 |
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| 2011 |
Wu X, Yang Z, Li Y, Hogerkorp C, Schief W, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo N, McKee K, OʼDell S, Louder MK, Wycuff D, ... ... Nabel GJ, et al. 147 Rational Design of Envelope Surface Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1 Jaids Journal of Acquired Immune Deficiency Syndromes. 56: 60. DOI: 10.1097/01.Qai.0000397332.57116.29 |
0.351 |
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| 2010 |
Nabel GJ, Fauci AS. Induction of unnatural immunity: prospects for a broadly protective universal influenza vaccine. Nature Medicine. 16: 1389-91. PMID 21135852 DOI: 10.1038/Nm1210-1389 |
0.418 |
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| 2010 |
Song K, Bolton DL, Wei CJ, Wilson RL, Camp JV, Bao S, Mattapallil JJ, Herzenberg LA, Herzenberg LA, Andrews CA, Sadoff JC, Goudsmit J, Pau MG, Seder RA, Kozlowski PA, ... Nabel GJ, et al. Genetic immunization in the lung induces potent local and systemic immune responses. Proceedings of the National Academy of Sciences of the United States of America. 107: 22213-8. PMID 21135247 DOI: 10.1073/Pnas.1015536108 |
0.401 |
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| 2010 |
Ledgerwood JE, Costner P, Desai N, Holman L, Enama ME, Yamshchikov G, Mulangu S, Hu Z, Andrews CA, Sheets RA, Koup RA, Roederer M, Bailer R, Mascola JR, Pau MG, ... ... Nabel GJ, et al. A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults. Vaccine. 29: 304-13. PMID 21034824 DOI: 10.1016/J.Vaccine.2010.10.037 |
0.445 |
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| 2010 |
Jaoko W, Karita E, Kayitenkore K, Omosa-Manyonyi G, Allen S, Than S, Adams EM, Graham BS, Koup RA, Bailer RT, Smith C, Dally L, Farah B, Anzala O, Muvunyi CM, ... ... Nabel GJ, et al. Safety and immunogenicity study of Multiclade HIV-1 adenoviral vector vaccine alone or as boost following a multiclade HIV-1 DNA vaccine in Africa. Plos One. 5: e12873. PMID 20877623 DOI: 10.1371/Journal.Pone.0012873 |
0.425 |
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| 2010 |
Sun Y, Santra S, Buzby AP, Mascola JR, Nabel GJ, Letvin NL. Recombinant vector-induced HIV/SIV-specific CD4+ T lymphocyte responses in rhesus monkeys. Virology. 406: 48-55. PMID 20667574 DOI: 10.1016/J.Virol.2010.07.004 |
0.413 |
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| 2010 |
Wei CJ, Boyington JC, McTamney PM, Kong WP, Pearce MB, Xu L, Andersen H, Rao S, Tumpey TM, Yang ZY, Nabel GJ. Induction of broadly neutralizing H1N1 influenza antibodies by vaccination. Science (New York, N.Y.). 329: 1060-4. PMID 20647428 DOI: 10.1126/Science.1192517 |
0.397 |
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| 2010 |
Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, ... ... Nabel GJ, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science (New York, N.Y.). 329: 856-61. PMID 20616233 DOI: 10.1126/Science.1187659 |
0.423 |
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| 2010 |
Zhou T, Georgiev I, Wu X, Yang ZY, Dai K, Finzi A, Kwon YD, Scheid JF, Shi W, Xu L, Yang Y, Zhu J, Nussenzweig MC, Sodroski J, Shapiro L, ... Nabel GJ, et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science (New York, N.Y.). 329: 811-7. PMID 20616231 DOI: 10.1126/Science.1192819 |
0.393 |
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| 2010 |
Rosenberg ES, Graham BS, Chan ES, Bosch RJ, Stocker V, Maenza J, Markowitz M, Little S, Sax PE, Collier AC, Nabel G, Saindon S, Flynn T, Kuritzkes D, Barouch DH, et al. Safety and immunogenicity of therapeutic DNA vaccination in individuals treated with antiretroviral therapy during acute/early HIV-1 infection. Plos One. 5: e10555. PMID 20479938 DOI: 10.1371/Journal.Pone.0010555 |
0.409 |
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| 2010 |
Wei CJ, Boyington JC, Dai K, Houser KV, Pearce MB, Kong WP, Yang ZY, Tumpey TM, Nabel GJ. Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design. Science Translational Medicine. 2: 24ra21. PMID 20375007 DOI: 10.1126/Scitranslmed.3000799 |
0.386 |
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| 2010 |
Rao SS, Kong WP, Wei CJ, Van Hoeven N, Gorres JP, Nason M, Andersen H, Tumpey TM, Nabel GJ. Comparative efficacy of hemagglutinin, nucleoprotein, and matrix 2 protein gene-based vaccination against H5N1 influenza in mouse and ferret. Plos One. 5: e9812. PMID 20352112 DOI: 10.1371/Journal.Pone.0009812 |
0.372 |
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| 2010 |
Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, ... ... Nabel GJ, et al. Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity. Nature Medicine. 16: 339-45. PMID 20139992 DOI: 10.1038/Nm.2104 |
0.462 |
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| 2010 |
Koup RA, Roederer M, Lamoreaux L, Fischer J, Novik L, Nason MC, Larkin BD, Enama ME, Ledgerwood JE, Bailer RT, Mascola JR, Nabel GJ, Graham BS. Priming immunization with DNA augments immunogenicity of recombinant adenoviral vectors for both HIV-1 specific antibody and T-cell responses. Plos One. 5: e9015. PMID 20126394 DOI: 10.1371/Journal.Pone.0009015 |
0.469 |
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| 2010 |
Akahata W, Yang ZY, Andersen H, Sun S, Holdaway HA, Kong WP, Lewis MG, Higgs S, Rossmann MG, Rao S, Nabel GJ. A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection. Nature Medicine. 16: 334-8. PMID 20111039 DOI: 10.1038/Nm.2105 |
0.449 |
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| 2010 |
Hood CL, Abraham J, Boyington JC, Leung K, Kwong PD, Nabel GJ. Biochemical and structural characterization of cathepsin L-processed Ebola virus glycoprotein: implications for viral entry and immunogenicity. Journal of Virology. 84: 2972-82. PMID 20053739 DOI: 10.1128/Jvi.02151-09 |
0.315 |
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| 2010 |
Ofek G, McKee K, Yang Y, Yang ZY, Skinner J, Guenaga FJ, Wyatt R, Zwick MB, Nabel GJ, Mascola JR, Kwong PD. Relationship between antibody 2F5 neutralization of HIV-1 and hydrophobicity of its heavy chain third complementarity-determining region. Journal of Virology. 84: 2955-62. PMID 20042512 DOI: 10.1128/Jvi.02257-09 |
0.323 |
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| 2010 |
Basavapathruni A, Yeh WW, Coffey RT, Whitney JB, Hraber PT, Giri A, Korber BT, Rao SS, Nabel GJ, Mascola JR, Seaman MS, Letvin NL. Envelope vaccination shapes viral envelope evolution following simian immunodeficiency virus infection in rhesus monkeys. Journal of Virology. 84: 953-63. PMID 19906933 DOI: 10.1128/Jvi.01679-09 |
0.43 |
|
| 2010 |
Cheng C, Gall JG, Nason M, King CR, Koup RA, Roederer M, McElrath MJ, Morgan CA, Churchyard G, Baden LR, Duerr AC, Keefer MC, Graham BS, Nabel GJ. Differential specificity and immunogenicity of adenovirus type 5 neutralizing antibodies elicited by natural infection or immunization. Journal of Virology. 84: 630-8. PMID 19846512 DOI: 10.1128/Jvi.00866-09 |
0.456 |
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| 2009 |
Chen L, Kwon YD, Zhou T, Wu X, O'Dell S, Cavacini L, Hessell AJ, Pancera M, Tang M, Xu L, Yang ZY, Zhang MY, Arthos J, Burton DR, Dimitrov DS, ... Nabel GJ, et al. Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science (New York, N.Y.). 326: 1123-7. PMID 19965434 DOI: 10.1126/Science.1175868 |
0.37 |
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| 2009 |
Kwong PD, Mascola JR, Nabel GJ. Mining the B cell repertoire for broadly neutralizing monoclonal antibodies to HIV-1. Cell Host & Microbe. 6: 292-4. PMID 19837366 DOI: 10.1016/J.Chom.2009.09.008 |
0.404 |
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| 2009 |
Graham BS, Ledgerwood JE, Nabel GJ. Vaccine development in the twenty-first century: Changing paradigms for elusive viruses Clinical Pharmacology and Therapeutics. 86: 234-236. PMID 19707212 DOI: 10.1038/Clpt.2009.128 |
0.369 |
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| 2009 |
Santra S, Sun Y, Korioth-Schmitz B, Fitzgerald J, Charbonneau C, Santos G, Seaman MS, Ratcliffe SJ, Montefiori DC, Nabel GJ, Ertl HCJ, Letvin NL. Heterologous prime/boost immunizations of rhesus monkeys using chimpanzee adenovirus vectors Vaccine. 27: 5837-5845. PMID 19660588 DOI: 10.1016/J.Vaccine.2009.07.050 |
0.461 |
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| 2009 |
Sun Y, Bailer RT, Rao SS, Mascola JR, Nabel GJ, Koup RA, Letvin NL. Systemic and mucosal T-lymphocyte activation induced by recombinant adenovirus vaccines in rhesus monkeys. Journal of Virology. 83: 10596-604. PMID 19656883 DOI: 10.1128/Jvi.01170-09 |
0.384 |
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| 2009 |
Whitney JB, Luedemann C, Hraber P, Rao SS, Mascola JR, Nabel GJ, Letvin NL. T-cell vaccination reduces simian immunodeficiency virus levels in semen. Journal of Virology. 83: 10840-3. PMID 19640980 DOI: 10.1128/Jvi.01202-09 |
0.463 |
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| 2009 |
Honda M, Wang R, Kong WP, Kanekiyo M, Akahata W, Xu L, Matsuo K, Natarajan K, Robinson H, Asher TE, Price DA, Douek DC, Margulies DH, Nabel GJ. Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity. Journal of Immunology (Baltimore, Md. : 1950). 183: 2425-34. PMID 19620307 DOI: 10.4049/Jimmunol.0900581 |
0.427 |
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| 2009 |
Nabel GJ. Protecting against future shock--inhalational anthrax. The New England Journal of Medicine. 361: 191-3. PMID 19587345 DOI: 10.1056/Nejme0903259 |
0.312 |
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| 2009 |
Dey B, Svehla K, Xu L, Wycuff D, Zhou T, Voss G, Phogat A, Chakrabarti BK, Li Y, Shaw G, Kwong PD, Nabel GJ, Mascola JR, Wyatt RT. Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site. Plos Pathogens. 5: e1000445. PMID 19478876 DOI: 10.1371/Journal.Ppat.1000445 |
0.359 |
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| 2009 |
Wang L, Cheng C, Ko SY, Kong WP, Kanekiyo M, Einfeld D, Schwartz RM, King CR, Gall JG, Nabel GJ. Delivery of human immunodeficiency virus vaccine vectors to the intestine induces enhanced mucosal cellular immunity. Journal of Virology. 83: 7166-75. PMID 19420074 DOI: 10.1128/Jvi.00374-09 |
0.454 |
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| 2009 |
Keele BF, Li H, Learn GH, Hraber P, Giorgi EE, Grayson T, Sun C, Chen Y, Yeh WW, Letvin NL, Mascola JR, Nabel GJ, Haynes BF, Bhattacharya T, Perelson AS, et al. Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. The Journal of Experimental Medicine. 206: 1117-34. PMID 19414559 DOI: 10.1084/Jem.20082831 |
0.376 |
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| 2009 |
Sullivan NJ, Martin JE, Graham BS, Nabel GJ. Correlates of protective immunity for Ebola vaccines: implications for regulatory approval by the animal rule. Nature Reviews. Microbiology. 7: 393-400. PMID 19369954 DOI: 10.1038/Nrmicro2129 |
0.404 |
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| 2009 |
Rao SS, Styles D, Kong W, Andrews C, Gorres JP, Nabel GJ. A gene-based avian influenza vaccine in poultry. Poultry Science. 88: 860-6. PMID 19276436 DOI: 10.3382/Ps.2008-00360 |
0.413 |
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| 2009 |
Wu L, Zhou T, Yang ZY, Svehla K, O'Dell S, Louder MK, Xu L, Mascola JR, Burton DR, Hoxie JA, Doms RW, Kwong PD, Nabel GJ. Enhanced exposure of the CD4-binding site to neutralizing antibodies by structural design of a membrane-anchored human immunodeficiency virus type 1 gp120 domain. Journal of Virology. 83: 5077-86. PMID 19264769 DOI: 10.1128/Jvi.02600-08 |
0.364 |
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| 2009 |
Kong WP, Wu L, Wallstrom TC, Fischer W, Yang ZY, Ko SY, Letvin NL, Haynes BF, Hahn BH, Korber B, Nabel GJ. Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination. Journal of Virology. 83: 2201-15. PMID 19109395 DOI: 10.1128/Jvi.02256-08 |
0.476 |
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| 2009 |
Keating CP, Hill MK, Hawkes DJ, Smyth RP, Isel C, Le SY, Palmenberg AC, Marshall JA, Marquet R, Nabel GJ, Mak J. The A-rich RNA sequences of HIV-1 pol are important for the synthesis of viral cDNA. Nucleic Acids Research. 37: 945-56. PMID 19106143 DOI: 10.1093/Nar/Gkn1015 |
0.342 |
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| 2009 |
Ko SY, Cheng C, Kong WP, Wang L, Kanekiyo M, Einfeld D, King CR, Gall JG, Nabel GJ. Enhanced induction of intestinal cellular immunity by oral priming with enteric adenovirus 41 vectors. Journal of Virology. 83: 748-56. PMID 18987146 DOI: 10.1128/Jvi.01811-08 |
0.407 |
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| 2009 |
Basavapathruni A, Yeh W, Coffey R, Whitney J, Hraber P, Giri A, Rao S, Mascola J, Nabel G, Korber B, Seaman M, Letvin N. P04-41. Kinetics of antibody neutralization and viral evolution following envelope vaccination in SIV-infected rhesus monkeys Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P69 |
0.339 |
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| 2009 |
Zhou T, Yang Z, Xu L, Hessell A, Burton, Nabel G, Kwong P. P04-38. Crystal structure of gp120 in complex with the CD4-binding-site antibody b13 suggests precise targeting is needed for neutralization Retrovirology. 6: 66. DOI: 10.1186/1742-4690-6-S3-P66 |
0.366 |
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| 2009 |
Fischer W, Apetrei C, Hahn BH, Letvin NL, Nabel GJ, Korber BT. P20-21 LB. Gene-to-gene differences in evolutionary rate between HIV-1 and natural SIV from sooty mangabeys: Implications for vaccine tests in non-human primates Retrovirology. 6: P425. DOI: 10.1186/1742-4690-6-S3-P425 |
0.451 |
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| 2009 |
Letvin N, Mascola J, Rao S, Buzby A, Roederer M, Hudgens M, Gilbert P, Seder R, Douek D, Koup R, Graham B, Nabel G. P19-57 LB. Gene-based vaccination protects against mucosal infection by a heterologous highly pathogenic SIV isolate in rhesus monkeys Retrovirology. 6. DOI: 10.1186/1742-4690-6-S3-P421 |
0.392 |
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| 2009 |
Flatz L, Kong W, Ko S, Roychoudhuri R, Wang L, Xu L, Yang Z, Honda M, Pinschewer D, Nabel G. P19-37. Replication-defective lymphocytic choriomeningitis virus vectors boost cellular and humoral immunity after DNA or adenovirus vector priming Retrovirology. 6: 357. DOI: 10.1186/1742-4690-6-S3-P357 |
0.449 |
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| 2009 |
Ko S, Wang L, Cheng C, Kong W, Gall J, King R, Nabel G. P17-27. Development of recombinant adenovirus 28 vectors for HIV vaccines Retrovirology. 6: 309. DOI: 10.1186/1742-4690-6-S3-P309 |
0.421 |
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| 2009 |
Ledgerwood JE, Novik L, Enama ME, Gordon IJ, Holman LA, Nason MC, Bailer RT, Roederer M, Koup RA, Mascola JR, Nabel GJ, Graham BS. P14-10. Comparable immunogenicity of VRC DNA and rAd5 HIV-1 vaccines delivered by intramuscular, subcutaneous and intradermal routes in healthy adults (VRC 011) Retrovirology. 6: P198. DOI: 10.1186/1742-4690-6-S3-P198 |
0.394 |
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| 2009 |
Pegu A, Boyington JC, Kong W, Shi W, Kwong PD, Nabel GJ. P13-01. Crystal structure and function of a monoclonal antibody against primate CD4 that blocks HIV/SIV infection Retrovirology. 6: P183. DOI: 10.1186/1742-4690-6-S3-P183 |
0.37 |
|
| 2009 |
Nabel GJ. 179 Rational Vaccine Design and the Development of an AIDS Vaccine Jaids Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.Qai.0000351134.09833.3A |
0.351 |
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| 2008 |
Rao S, Kong WP, Wei CJ, Yang ZY, Nason M, Styles D, DeTolla LJ, Panda A, Sorrell EM, Song H, Wan H, Ramirez-Nieto GC, Perez D, Nabel GJ. Multivalent HA DNA vaccination protects against highly pathogenic H5N1 avian influenza infection in chickens and mice. Plos One. 3: e2432. PMID 19293944 DOI: 10.1371/Journal.Pone.0002432 |
0.404 |
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| 2008 |
Martin JE, Louder MK, Holman LA, Gordon IJ, Enama ME, Larkin BD, Andrews CA, Vogel L, Koup RA, Roederer M, Bailer RT, Gomez PL, Nason M, Mascola JR, Nabel GJ, et al. A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial. Vaccine. 26: 6338-43. PMID 18824060 DOI: 10.1016/J.Vaccine.2008.09.026 |
0.395 |
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| 2008 |
Wu X, Sambor A, Nason MC, Yang ZY, Wu L, Zolla-Pazner S, Nabel GJ, Mascola JR. Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses. Virology. 380: 285-95. PMID 18804254 DOI: 10.1016/J.Virol.2008.07.007 |
0.419 |
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| 2008 |
Belyakov IM, Ahlers JD, Nabel GJ, Moss B, Berzofsky JA. Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization. Virology. 381: 106-15. PMID 18793787 DOI: 10.1016/J.Virol.2008.08.019 |
0.392 |
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| 2008 |
Santra S, Korber BT, Muldoon M, Barouch DH, Nabel GJ, Gao F, Hahn BH, Haynes BF, Letvin NL. A centralized gene-based HIV-1 vaccine elicits broad cross-clade cellular immune responses in rhesus monkeys. Proceedings of the National Academy of Sciences of the United States of America. 105: 10489-94. PMID 18650391 DOI: 10.1073/Pnas.0803352105 |
0.468 |
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| 2008 |
Leung K, Kim JO, Ganesh L, Kabat J, Schwartz O, Nabel GJ. HIV-1 assembly: viral glycoproteins segregate quantally to lipid rafts that associate individually with HIV-1 capsids and virions. Cell Host & Microbe. 3: 285-92. PMID 18474355 DOI: 10.1016/J.Chom.2008.04.004 |
0.369 |
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| 2008 |
Woffendin C, Ranga U, Nabel GJ. Development of molecular genetic interventions for HIV infection. Current Protocols in Human Genetics. Unit 13.6. PMID 18428255 DOI: 10.1002/0471142905.Hg1306S12 |
0.366 |
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| 2008 |
Wei CJ, Xu L, Kong WP, Shi W, Canis K, Stevens J, Yang ZY, Dell A, Haslam SM, Wilson IA, Nabel GJ. Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. Journal of Virology. 82: 6200-8. PMID 18417563 DOI: 10.1128/Jvi.00187-08 |
0.399 |
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| 2007 |
Martin JE, Pierson TC, Hubka S, Rucker S, Gordon IJ, Enama ME, Andrews CA, Xu Q, Davis BS, Nason M, Fay M, Koup RA, Roederer M, Bailer RT, Gomez PL, ... ... Nabel GJ, et al. A West Nile virus DNA vaccine induces neutralizing antibody in healthy adults during a phase 1 clinical trial. The Journal of Infectious Diseases. 196: 1732-40. PMID 18190252 DOI: 10.1086/523650 |
0.405 |
|
| 2007 |
Zampieri CA, Sullivan NJ, Nabel GJ. Immunopathology of highly virulent pathogens: insights from Ebola virus. Nature Immunology. 8: 1159-64. PMID 17952040 DOI: 10.1038/Ni1519 |
0.374 |
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| 2007 |
Yang ZY, Wei CJ, Kong WP, Wu L, Xu L, Smith DF, Nabel GJ. Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity. Science (New York, N.Y.). 317: 825-8. PMID 17690300 DOI: 10.1126/Science.1135165 |
0.368 |
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| 2007 |
Letvin NL, Rao SS, Dang V, Buzby AP, Korioth-Schmitz B, Dombagoda D, Parvani JG, Clarke RH, Bar L, Carlson KR, Kozlowski PA, Hirsch VM, Mascola JR, Nabel GJ. No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys. Journal of Virology. 81: 12368-74. PMID 17686853 DOI: 10.1128/Jvi.00822-07 |
0.433 |
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| 2007 |
Zhu Z, Chakraborti S, He Y, Roberts A, Sheahan T, Xiao X, Hensley LE, Prabakaran P, Rockx B, Sidorov IA, Corti D, Vogel L, Feng Y, Kim JO, Wang LF, ... ... Nabel GJ, et al. Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 104: 12123-8. PMID 17620608 DOI: 10.1073/Pnas.0701000104 |
0.31 |
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| 2007 |
Nabel GJ. Mapping the future of HIV vaccines. Nature Reviews. Microbiology. 5: 482-4. PMID 17571457 DOI: 10.1038/Nrmicro1713 |
0.397 |
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| 2007 |
Catanzaro AT, Roederer M, Koup RA, Bailer RT, Enama ME, Nason MC, Martin JE, Rucker S, Andrews CA, Gomez PL, Mascola JR, Nabel GJ, Graham BS. Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine. Vaccine. 25: 4085-92. PMID 17391815 DOI: 10.1016/J.Vaccine.2007.02.050 |
0.449 |
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| 2007 |
Tavel JA, Martin JE, Kelly GG, Enama ME, Shen JM, Gomez PL, Andrews CA, Koup RA, Bailer RT, Stein JA, Roederer M, Nabel GJ, Graham BS. Safety and immunogenicity of a Gag-Pol candidate HIV-1 DNA vaccine administered by a needle-free device in HIV-1-seronegative subjects. Journal of Acquired Immune Deficiency Syndromes (1999). 44: 601-5. PMID 17325604 DOI: 10.1097/Qai.0B013E3180417Cb6 |
0.389 |
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| 2007 |
Cheng C, Gall JG, Kong WP, Sheets RL, Gomez PL, King CR, Nabel GJ. Mechanism of ad5 vaccine immunity and toxicity: fiber shaft targeting of dendritic cells. Plos Pathogens. 3: e25. PMID 17319743 DOI: 10.1371/Journal.Ppat.0030025 |
0.412 |
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| 2007 |
Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature. 445: 732-7. PMID 17301785 DOI: 10.1038/Nature05580 |
0.36 |
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| 2007 |
Smith AL, Ganesh L, Leung K, Jongstra-Bilen J, Jongstra J, Nabel GJ. Leukocyte-specific protein 1 interacts with DC-SIGN and mediates transport of HIV to the proteasome in dendritic cells. The Journal of Experimental Medicine. 204: 421-30. PMID 17296787 DOI: 10.1084/Jem.20061604 |
0.378 |
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| 2007 |
Lemiale F, Haddada H, Nabel GJ, Brough DE, King CR, Gall JG. Novel adenovirus vaccine vectors based on the enteric-tropic serotype 41. Vaccine. 25: 2074-84. PMID 17250935 DOI: 10.1016/J.Vaccine.2006.11.025 |
0.374 |
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| 2007 |
Shu Y, Winfrey S, Yang Zy, Xu L, Rao SS, Srivastava I, Barnett SW, Nabel GJ, Mascola JR. Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs Vaccine. 25: 1398-1408. PMID 17113201 DOI: 10.1016/J.Vaccine.2006.10.046 |
0.474 |
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| 2007 |
Zampieri CA, Fortin JF, Nolan GP, Nabel GJ. The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity. Journal of Virology. 81: 1230-40. PMID 17108034 DOI: 10.1128/Jvi.01586-06 |
0.325 |
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| 2007 |
Kim JO, Chakrabarti BK, Guha-Niyogi A, Louder MK, Mascola JR, Ganesh L, Nabel GJ. Lysis of human immunodeficiency virus type 1 by a specific secreted human phospholipase A2. Journal of Virology. 81: 1444-50. PMID 17093191 DOI: 10.1128/Jvi.01790-06 |
0.437 |
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| 2006 |
Catanzaro AT, Koup RA, Roederer M, Bailer RT, Enama ME, Moodie Z, Gu L, Martin JE, Novik L, Chakrabarti BK, Butman BT, Gall JG, King CR, Andrews CA, Sheets R, ... ... Nabel GJ, et al. Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector. The Journal of Infectious Diseases. 194: 1638-49. PMID 17109335 DOI: 10.1086/509258 |
0.441 |
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| 2006 |
Kong WP, Hood C, Yang ZY, Wei CJ, Xu L, García-Sastre A, Tumpey TM, Nabel GJ. Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination. Proceedings of the National Academy of Sciences of the United States of America. 103: 15987-91. PMID 17043214 DOI: 10.1073/Pnas.0607564103 |
0.44 |
|
| 2006 |
Liao HX, Sutherland LL, Xia SM, Brock ME, Scearce RM, Vanleeuwen S, Alam SM, McAdams M, Weaver EA, Camacho Z, Ma BJ, Li Y, Decker JM, Nabel GJ, Montefiori DC, et al. A group M consensus envelope glycoprotein induces antibodies that neutralize subsets of subtype B and C HIV-1 primary viruses. Virology. 353: 268-82. PMID 17039602 DOI: 10.1016/J.Virol.2006.04.043 |
0.407 |
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| 2006 |
Martin JE, Sullivan NJ, Enama ME, Gordon IJ, Roederer M, Koup RA, Bailer RT, Chakrabarti BK, Bailey MA, Gomez PL, Andrews CA, Moodie Z, Gu L, Stein JA, Nabel GJ, et al. A DNA vaccine for Ebola virus is safe and immunogenic in a phase I clinical trial. Clinical and Vaccine Immunology : Cvi. 13: 1267-77. PMID 16988008 DOI: 10.1128/Cvi.00162-06 |
0.43 |
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| 2006 |
Sun Y, Schmitz JE, Buzby AP, Barker BR, Rao SS, Xu L, Yang ZY, Mascola JR, Nabel GJ, Letvin NL. Virus-specific cellular immune correlates of survival in vaccinated monkeys after simian immunodeficiency virus challenge. Journal of Virology. 80: 10950-6. PMID 16943292 DOI: 10.1128/Jvi.01458-06 |
0.419 |
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| 2006 |
Yu JS, Liao HX, Gerdon AE, Huffman B, Scearce RM, McAdams M, Alam SM, Popernack PM, Sullivan NJ, Wright D, Cliffel DE, Nabel GJ, Haynes BF. Detection of Ebola virus envelope using monoclonal and polyclonal antibodies in ELISA, surface plasmon resonance and a quartz crystal microbalance immunosensor. Journal of Virological Methods. 137: 219-28. PMID 16857271 DOI: 10.1016/J.Jviromet.2006.06.014 |
0.303 |
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| 2006 |
Weaver EA, Lu Z, Camacho ZT, Moukdar F, Liao HX, Ma BJ, Muldoon M, Theiler J, Nabel GJ, Letvin NL, Korber BT, Hahn BH, Haynes BF, Gao F. Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen. Journal of Virology. 80: 6745-56. PMID 16809280 DOI: 10.1128/Jvi.02484-05 |
0.455 |
|
| 2006 |
Letvin NL, Mascola JR, Sun Y, Gorgone DA, Buzby AP, Xu L, Yang ZY, Chakrabarti B, Rao SS, Schmitz JE, Montefiori DC, Barker BR, Bookstein FL, Nabel GJ. Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys. Science (New York, N.Y.). 312: 1530-3. PMID 16763152 DOI: 10.1126/Science.1124226 |
0.441 |
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| 2006 |
Mattapallil JJ, Douek DC, Buckler-White A, Montefiori D, Letvin NL, Nabel GJ, Roederer M. Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge Journal of Experimental Medicine. 203: 1533-1541. PMID 16735692 DOI: 10.1084/Jem.20060657 |
0.376 |
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| 2006 |
Wu L, Yang ZY, Xu L, Welcher B, Winfrey S, Shao Y, Mascola JR, Nabel GJ. Cross-clade recognition and neutralization by the V3 region from clade C human immunodeficiency virus-1 envelope. Vaccine. 24: 4995-5002. PMID 16690178 DOI: 10.1016/J.Vaccine.2006.03.083 |
0.377 |
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| 2006 |
Sullivan NJ, Geisbert TW, Geisbert JB, Shedlock DJ, Xu L, Lamoreaux L, Custers JH, Popernack PM, Yang ZY, Pau MG, Roederer M, Koup RA, Goudsmit J, Jahrling PB, Nabel GJ. Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs. Plos Medicine. 3: e177. PMID 16683867 DOI: 10.1371/Journal.Pmed.0030177 |
0.433 |
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| 2006 |
Ganesh L, Yoshimoto T, Moorthy NC, Akahata W, Boehm M, Nabel EG, Nabel GJ. Protein methyltransferase 2 inhibits NF-kappaB function and promotes apoptosis. Molecular and Cellular Biology. 26: 3864-74. PMID 16648481 DOI: 10.1128/Mcb.26.10.3864-3874.2006 |
0.729 |
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| 2006 |
Acierno PM, Schmitz JE, Gorgone DA, Sun Y, Santra S, Seaman MS, Newberg MH, Mascola JR, Nabel GJ, Panicali D, Letvin NL. Preservation of functional virus-specific memory CD8+ T lymphocytes in vaccinated, simian human immunodeficiency virus-infected rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 176: 5338-45. PMID 16622001 DOI: 10.4049/Jimmunol.176.9.5338 |
0.373 |
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| 2006 |
Sheets RL, Stein J, Manetz TS, Duffy C, Nason M, Andrews C, Kong WP, Nabel GJ, Gomez PL. Biodistribution of DNA plasmid vaccines against HIV-1, Ebola, Severe Acute Respiratory Syndrome, or West Nile virus is similar, without integration, despite differing plasmid backbones or gene inserts. Toxicological Sciences : An Official Journal of the Society of Toxicology. 91: 610-9. PMID 16569729 DOI: 10.1093/Toxsci/Kfj169 |
0.432 |
|
| 2006 |
Douek DC, Kwong PD, Nabel GJ. The rational design of an AIDS vaccine Cell. 124: 677-681. PMID 16497577 DOI: 10.1016/J.Cell.2006.02.005 |
0.432 |
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| 2006 |
Kong WP, Xu L, Stadler K, Ulmer JB, Abrignani S, Rappuoli R, Nabel GJ. Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization. Journal of Virology. 79: 13915-23. PMID 16254327 DOI: 10.1128/Jvi.79.22.13915-13923.2005 |
0.43 |
|
| 2006 |
Rao SS, Gomez P, Mascola JR, Dang V, Krivulka GR, Yu F, Lord CI, Shen L, Bailer R, Nabel GJ, Letvin NL. Comparative evaluation of three different intramuscular delivery methods for DNA immunization in a nonhuman primate animal model. Vaccine. 24: 367-73. PMID 16194587 DOI: 10.1016/J.Vaccine.2005.07.072 |
0.406 |
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| 2006 |
Zhou T, Xu L, Dey B, Hessell AJ, Majeed S, Van Ryk D, Xiang S, Yang X, Zhang M, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, ... Nabel GJ, et al. Retrovirology. 3: S22. DOI: 10.1186/1742-4690-3-S1-S22 |
0.364 |
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| 2006 |
Nabel GJ. A multiclade DNA/Ad vaccines for AIDS: the present and next generation Retrovirology. 3. DOI: 10.1186/1742-4690-3-S1-S19 |
0.441 |
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| 2005 |
Epstein SL, Kong WP, Misplon JA, Lo CY, Tumpey TM, Xu L, Nabel GJ. Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein. Vaccine. 23: 5404-10. PMID 16011865 DOI: 10.1016/J.Vaccine.2005.04.047 |
0.433 |
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| 2005 |
Reimann KA, Parker RA, Seaman MS, Beaudry K, Beddall M, Peterson L, Williams KC, Veazey RS, Montefiori DC, Mascola JR, Nabel GJ, Letvin NL. Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses. Journal of Virology. 79: 8878-85. PMID 15994781 DOI: 10.1128/Jvi.79.14.8878-8885.2005 |
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| 2005 |
Barouch DH, Yang ZY, Kong WP, Korioth-Schmitz B, Sumida SM, Truitt DM, Kishko MG, Arthur JC, Miura A, Mascola JR, Letvin NL, Nabel GJ. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates. Journal of Virology. 79: 8828-34. PMID 15994776 DOI: 10.1128/Jvi.79.14.8828-8834.2005 |
0.471 |
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| 2005 |
Nabel GJ. Immunology. Close to the edge: neutralizing the HIV-1 envelope. Science (New York, N.Y.). 308: 1878-9. PMID 15976295 DOI: 10.1126/Science.1114854 |
0.37 |
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| 2005 |
Podsakoff GM, Engel BC, Carbonaro DA, Choi C, Smogorzewska EM, Bauer G, Selander D, Csik S, Wilson K, Betts MR, Koup RA, Nabel GJ, Bishop K, King S, Schmidt M, et al. Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 77-86. PMID 15963923 DOI: 10.1016/J.Ymthe.2005.02.024 |
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| 2005 |
Wu L, Kong WP, Nabel GJ. Enhanced breadth of CD4 T-cell immunity by DNA prime and adenovirus boost immunization to human immunodeficiency virus Env and Gag immunogens. Journal of Virology. 79: 8024-31. PMID 15956548 DOI: 10.1128/Jvi.79.13.8024-8031.2005 |
0.415 |
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| 2005 |
Santra S, Seaman MS, Xu L, Barouch DH, Lord CI, Lifton MA, Gorgone DA, Beaudry KR, Svehla K, Welcher B, Chakrabarti BK, Huang Y, Yang ZY, Mascola JR, Nabel GJ, et al. Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. Journal of Virology. 79: 6516-22. PMID 15858035 DOI: 10.1128/Jvi.79.10.6516-6522.2005 |
0.421 |
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| 2005 |
Chakrabarti BK, Ling X, Yang ZY, Montefiori DC, Panet A, Kong WP, Welcher B, Louder MK, Mascola JR, Nabel GJ. Expanded breadth of virus neutralization after immunization with a multiclade envelope HIV vaccine candidate. Vaccine. 23: 3434-45. PMID 15837367 DOI: 10.1016/J.Vaccine.2005.01.099 |
0.419 |
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| 2005 |
Sun Y, Schmitz JE, Acierno PM, Santra S, Subbramanian RA, Barouch DH, Gorgone DA, Lifton MA, Beaudry KR, Manson K, Philippon V, Xu L, Maecker HT, Mascola JR, Panicali D, ... Nabel GJ, et al. Dysfunction of simian immunodeficiency virus/simian human immunodeficiency virus-induced IL-2 expression by central memory CD4+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 4753-60. PMID 15814700 DOI: 10.4049/Jimmunol.174.8.4753 |
0.372 |
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| 2005 |
Seaman MS, Santra S, Newberg MH, Philippon V, Manson K, Xu L, Gelman RS, Panicali D, Mascola JR, Nabel GJ, Letvin NL. Vaccine-elicited memory cytotoxic T lymphocytes contribute to Mamu-A*01-associated control of simian/human immunodeficiency virus 89.6P replication in rhesus monkeys. Journal of Virology. 79: 4580-8. PMID 15795244 DOI: 10.1128/Jvi.79.8.4580-4588.2005 |
0.403 |
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| 2005 |
Barouch DH, Nabel GJ. Adenovirus vector-based vaccines for human immunodeficiency virus type 1. Human Gene Therapy. 16: 149-56. PMID 15761255 DOI: 10.1089/Hum.2005.16.149 |
0.428 |
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| 2005 |
Seaman MS, Xu L, Beaudry K, Martin KL, Beddall MH, Miura A, Sambor A, Chakrabarti BK, Huang Y, Bailer R, Koup RA, Mascola JR, Nabel GJ, Letvin NL. Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys. Journal of Virology. 79: 2956-63. PMID 15709015 DOI: 10.1128/Jvi.79.5.2956-2963.2005 |
0.485 |
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| 2005 |
Yang ZY, Werner HC, Kong WP, Leung K, Traggiai E, Lanzavecchia A, Nabel GJ. Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses. Proceedings of the National Academy of Sciences of the United States of America. 102: 797-801. PMID 15642942 DOI: 10.1073/Pnas.0409065102 |
0.371 |
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| 2005 |
Mascola JR, Sambor A, Beaudry K, Santra S, Welcher B, Louder MK, Vancott TC, Huang Y, Chakrabarti BK, Kong WP, Yang ZY, Xu L, Montefiori DC, Nabel GJ, Letvin NL. Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins. Journal of Virology. 79: 771-9. PMID 15613305 DOI: 10.1128/Jvi.79.2.771-779.2005 |
0.436 |
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| 2005 |
Akahata W, Yang ZY, Nabel GJ. Comparative immunogenicity of human immunodeficiency virus particles and corresponding polypeptides in a DNA vaccine. Journal of Virology. 79: 626-31. PMID 15596858 DOI: 10.1128/Jvi.79.1.626-631.2005 |
0.472 |
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| 2005 |
Sullivan NJ, Peterson M, Yang ZY, Kong WP, Duckers H, Nabel E, Nabel GJ. Ebola virus glycoprotein toxicity is mediated by a dynamin-dependent protein-trafficking pathway. Journal of Virology. 79: 547-53. PMID 15596847 DOI: 10.1128/Jvi.79.1.547-553.2005 |
0.377 |
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| 2005 |
Nabel G. Rational Design of AIDS Vaccines Retrovirology. 2: 1-1. DOI: 10.1186/1742-4690-2-S1-S28 |
0.49 |
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| 2005 |
Aoki K, Ohashi M, Kushida M, Yoshida K, Mandai M, Nabel GJ, Yoshida T. 708. Combination of Allogeneic Hematopoietic Stem Cell Transplantation and Allogeneic MHC Gene Transfer Against Solid Cancers Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.248 |
0.315 |
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| 2005 |
Martin J, Enama M, Koup R, Bailer R, Moodie Z, Roederer M, Nabel G, Graham B. VRC 004: Safety and Immunogenicity of a Multiclade HIV-1 DNA Vaccine in Healthy Uninfected Adults (VRC-HIVDNA009-00-VP) Journal of Allergy and Clinical Immunology. 115: 892. DOI: 10.1016/J.Jaci.2005.01.050 |
0.392 |
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| 2004 |
Huang Y, Yang ZY, Kong WP, Nabel GJ. Generation of synthetic severe acute respiratory syndrome coronavirus pseudoparticles: implications for assembly and vaccine production. Journal of Virology. 78: 12557-65. PMID 15507643 DOI: 10.1128/Jvi.78.22.12557-12565.2004 |
0.37 |
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| 2004 |
Ganesh L, Leung K, Loré K, Levin R, Panet A, Schwartz O, Koup RA, Nabel GJ. Infection of specific dendritic cells by CCR5-tropic human immunodeficiency virus type 1 promotes cell-mediated transmission of virus resistant to broadly neutralizing antibodies. Journal of Virology. 78: 11980-7. PMID 15479838 DOI: 10.1128/Jvi.78.21.11980-11987.2004 |
0.391 |
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| 2004 |
Letvin NL, Huang Y, Chakrabarti BK, Xu L, Seaman MS, Beaudry K, Korioth-Schmitz B, Yu F, Rohne D, Martin KL, Miura A, Kong WP, Yang ZY, Gelman RS, Golubeva OG, ... ... Nabel GJ, et al. Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. Journal of Virology. 78: 7490-7. PMID 15220422 DOI: 10.1128/Jvi.78.14.7490-7497.2004 |
0.493 |
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| 2004 |
Yang ZY, Huang Y, Ganesh L, Leung K, Kong WP, Schwartz O, Subbarao K, Nabel GJ. pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. Journal of Virology. 78: 5642-50. PMID 15140961 DOI: 10.1128/Jvi.78.11.5642-5650.2004 |
0.383 |
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| 2004 |
Barouch DH, Pau MG, Custers JH, Koudstaal W, Kostense S, Havenga MJ, Truitt DM, Sumida SM, Kishko MG, Arthur JC, Korioth-Schmitz B, Newberg MH, Gorgone DA, Lifton MA, Panicali DL, ... Nabel GJ, et al. Immunogenicity of recombinant adenovirus serotype 35 vaccine in the presence of pre-existing anti-Ad5 immunity. Journal of Immunology (Baltimore, Md. : 1950). 172: 6290-7. PMID 15128818 DOI: 10.4049/Jimmunol.172.10.6290 |
0.359 |
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| 2004 |
Yang ZY, Chakrabarti BK, Xu L, Welcher B, Kong WP, Leung K, Panet A, Mascola JR, Nabel GJ. Selective modification of variable loops alters tropism and enhances immunogenicity of human immunodeficiency virus type 1 envelope. Journal of Virology. 78: 4029-36. PMID 15047819 DOI: 10.1128/Jvi.78.8.4029-4036.2004 |
0.391 |
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| 2004 |
Yang ZY, Kong WP, Huang Y, Roberts A, Murphy BR, Subbarao K, Nabel GJ. A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice. Nature. 428: 561-4. PMID 15024391 DOI: 10.1038/Nature02463 |
0.449 |
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| 2004 |
Burton DR, Desrosiers RC, Doms RW, Koff WC, Kwong PD, Moore JP, Nabel GJ, Sodroski J, Wilson IA, Wyatt RT. HIV vaccine design and the neutralizing antibody problem. Nature Immunology. 5: 233-6. PMID 14985706 DOI: 10.1038/Ni0304-233 |
0.427 |
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| 2004 |
Nabel GJ. Genetic, cellular and immune approaches to disease therapy: past and future. Nature Medicine. 10: 135-41. PMID 14760423 DOI: 10.1038/Nm990 |
0.32 |
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| 2004 |
Cen S, Niu M, Saadatmand J, Guo F, Huang Y, Nabel GJ, Kleiman L. Incorporation of pol into human immunodeficiency virus type 1 Gag virus-like particles occurs independently of the upstream Gag domain in Gag-pol. Journal of Virology. 78: 1042-9. PMID 14694138 DOI: 10.1128/Jvi.78.2.1042-1049.2004 |
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| 2003 |
Ganesh L, Burstein E, Guha-Niyogi A, Louder MK, Mascola JR, Klomp LW, Wijmenga C, Duckett CS, Nabel GJ. The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. Nature. 426: 853-7. PMID 14685242 DOI: 10.1038/Nature02171 |
0.415 |
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| 2003 |
Kong WP, Huang Y, Yang ZY, Chakrabarti BK, Moodie Z, Nabel GJ. Immunogenicity of multiple gene and clade human immunodeficiency virus type 1 DNA vaccines. Journal of Virology. 77: 12764-72. PMID 14610198 DOI: 10.1128/Jvi.77.23.12764-12772.2003 |
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| 2003 |
Lemiale F, Kong WP, Akyürek LM, Ling X, Huang Y, Chakrabarti BK, Eckhaus M, Nabel GJ. Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system. Journal of Virology. 77: 10078-87. PMID 12941918 DOI: 10.1128/Jvi.77.18.10078-10087.2003 |
0.474 |
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| 2003 |
Sullivan N, Yang ZY, Nabel GJ. Ebola virus pathogenesis: Implications for vaccines and therapies Journal of Virology. 77: 9733-9737. PMID 12941881 DOI: 10.1128/Jvi.77.18.9733-9737.2003 |
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| 2003 |
Tritel M, Stoddard AM, Flynn BJ, Darrah PA, Wu CY, Wille U, Shah JA, Huang Y, Xu L, Betts MR, Nabel GJ, Seder RA. Prime-boost vaccination with HIV-1 Gag protein and cytosine phosphate guanosine oligodeoxynucleotide, followed by adenovirus, induces sustained and robust humoral and cellular immune responses. Journal of Immunology (Baltimore, Md. : 1950). 171: 2538-47. PMID 12928404 DOI: 10.4049/Jimmunol.171.5.2538 |
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| 2003 |
Sullivan NJ, Geisbert TW, Geisbert JB, Xu L, Yang ZY, Roederer M, Koup RA, Jahrling PB, Nabel GJ. Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates. Nature. 424: 681-4. PMID 12904795 DOI: 10.1038/Nature01876 |
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| 2003 |
Barouch DH, McKay PF, Sumida SM, Santra S, Jackson SS, Gorgone DA, Lifton MA, Chakrabarti BK, Xu L, Nabel GJ, Letvin NL. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. Journal of Virology. 77: 8729-35. PMID 12885892 DOI: 10.1128/Jvi.77.16.8729-8735.2003 |
0.429 |
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| 2003 |
Klausner RD, Fauci AS, Corey L, Nabel GJ, Gayle H, Berkley S, Haynes BF, Baltimore D, Collins C, Douglas RG, Esparza J, Francis DP, Ganguly NK, Gerberding JL, Johnston MI, et al. Medicine. The need for a global HIV vaccine enterprise. Science (New York, N.Y.). 300: 2036-9. PMID 12829768 DOI: 10.1126/Science.1086916 |
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| 2003 |
Nabel GJ. Vaccine for AIDS and Ebola virus infection. Virus Research. 92: 213-7. PMID 12686432 DOI: 10.1016/S0168-1702(02)00354-4 |
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| 2003 |
Yang ZY, Wyatt LS, Kong WP, Moodie Z, Moss B, Nabel GJ. Overcoming immunity to a viral vaccine by DNA priming before vector boosting. Journal of Virology. 77: 799-803. PMID 12477888 DOI: 10.1128/Jvi.77.1.799-803.2003 |
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| 2002 |
Baig J, Levy DB, McKay PF, Schmitz JE, Santra S, Subbramanian RA, Kuroda MJ, Lifton MA, Gorgone DA, Wyatt LS, Moss B, Huang Y, Chakrabarti BK, Xu L, Kong WP, ... ... Nabel GJ, et al. Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination. Journal of Virology. 76: 11484-90. PMID 12388710 DOI: 10.1128/Jvi.76.22.11484-11490.2002 |
0.47 |
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| 2002 |
Huang Y, Xu L, Sun Y, Nabel GJ. The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein. Molecular Cell. 10: 307-16. PMID 12191476 DOI: 10.1016/S1097-2765(02)00588-9 |
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| 2002 |
Nabel G, Makgoba W, Esparza J. HIV-1 diversity and vaccine development. Science (New York, N.Y.). 296: 2335. PMID 12090274 DOI: 10.1126/Science.296.5577.2335 |
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| 2002 |
Chakrabarti BK, Kong WP, Wu BY, Yang ZY, Friborg J, Ling X, King SR, Montefiori DC, Nabel GJ. Modifications of the human immunodeficiency virus envelope glycoprotein enhance immunogenicity for genetic immunization. Journal of Virology. 76: 5357-68. PMID 11991964 DOI: 10.1128/Jvi.76.11.5357-5368.2002 |
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| 2002 |
Nabel GJ. HIV vaccine strategies. Vaccine. 20: 1945-7. PMID 11983251 DOI: 10.1016/S0264-410X(02)00074-9 |
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| 2002 |
Moore AC, Kong WP, Chakrabarti BK, Nabel GJ. Effects of antigen and genetic adjuvants on immune responses to human immunodeficiency virus DNA vaccines in mice. Journal of Virology. 76: 243-50. PMID 11739689 DOI: 10.1128/Jvi.76.1.243-250.2002 |
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| 2001 |
Mascola JR, Nabel GJ. Vaccines for the prevention of HIV-1 disease. Current Opinion in Immunology. 13: 489-95. PMID 11498307 DOI: 10.1016/S0952-7915(00)00246-6 |
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| 2001 |
Akyürek LM, Nallamshetty S, Aoki K, San H, Yang ZY, Nabel GJ, Nabel EG. Coexpression of guanylate kinase with thymidine kinase enhances prodrug cell killing in vitro and suppresses vascular smooth muscle cell proliferation in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 779-86. PMID 11356082 DOI: 10.1006/Mthe.2001.0315 |
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| 2001 |
Huang Y, Kong WP, Nabel GJ. Human immunodeficiency virus type 1-specific immunity after genetic immunization is enhanced by modification of Gag and Pol expression. Journal of Virology. 75: 4947-51. PMID 11312370 DOI: 10.1128/Jvi.75.10.4947-4951.2001 |
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| 2001 |
Nabel GJ. Challenges and opportunities for development of an AIDS vaccine. Nature. 410: 1002-7. PMID 11309631 DOI: 10.1038/35073500 |
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| 2001 |
Aoki K, Kurooka M, Chen JJ, Petryniak J, Nabel EG, Nabel GJ. Extracellular matrix interacts with soluble CD95L: retention and enhancement of cytotoxicity. Nature Immunology. 2: 333-337. PMID 11276204 DOI: 10.1038/86336 |
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| 2001 |
Hottiger MO, Nabel GJ. Viral replication and the coactivators p300 and CBP. Trends in Microbiology. 8: 560-5. PMID 11115752 DOI: 10.1016/S0966-842X(00)01874-6 |
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| 2000 |
Sullivan NJ, Sanchez A, Rollin PE, Yang ZY, Nabel GJ. Development of a preventive vaccine for Ebola virus infection in primates. Nature. 408: 605-9. PMID 11117750 DOI: 10.1038/35046108 |
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| 2000 |
Nabel GJ, Sullivan NJ. Antibodies and resistance to natural HIV infection. The New England Journal of Medicine. 343: 1263-5. PMID 11071680 DOI: 10.1056/Nejm200010263431711 |
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| 2000 |
Aoki K, Akyürek LM, San H, Leung K, Parmacek MS, Nabel EG, Nabel GJ. Restricted expression of an adenoviral vector encoding Fas ligand (CD95L) enhances safety for cancer gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 1: 555-65. PMID 10933980 DOI: 10.1006/Mthe.2000.0076 |
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| 2000 |
Yang ZY, Duckers HJ, Sullivan NJ, Sanchez A, Nabel EG, Nabel GJ. Identification of the Ebola virus glycoprotein as the main viral determinant of vascular cell cytotoxicity and injury. Nature Medicine. 6: 886-9. PMID 10932225 DOI: 10.1038/78645 |
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| 2000 |
Friborg J, Kong W, Hottiger MO, Nabel GJ. p53 inhibition by the LANA protein of KSHV protects against cell death. Nature. 402: 889-94. PMID 10622254 DOI: 10.1038/47266 |
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| 1999 |
Hottiger MO, Dam TN, Nickoloff BJ, Johnson TM, Nabel GJ. Liposome-mediated gene transfer into human basal cell carcinoma Gene Therapy. 6: 1929-1935. PMID 10637444 DOI: 10.1038/Sj.Gt.3301036 |
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| 1999 |
Collins KL, Nabel GJ. Naturally attenuated HIV - Lessons for AIDS vaccines and treatment New England Journal of Medicine. 340: 1756-1757. PMID 10352170 DOI: 10.1056/Nejm199906033402210 |
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| 1999 |
Nabel GJ. Surviving Ebola virus infection. Nature Medicine. 5: 373-4. PMID 10202917 DOI: 10.1038/7363 |
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| 1999 |
Yang S, Delgado R, King SR, Woffendin C, Barker CS, Yang ZY, Xu L, Nolan GP, Nabel GJ. Generation of retroviral vector for clinical studies using transient transfection Human Gene Therapy. 10: 123-132. PMID 10022537 DOI: 10.1089/10430349950019255 |
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| 1999 |
Nabel GJ. Development of optimized vectors for gene therapy. Proceedings of the National Academy of Sciences of the United States of America. 96: 324-6. PMID 9892629 DOI: 10.1073/Pnas.96.2.324 |
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| 1998 |
Friborg J, Kong WP, Flowers CC, Flowers SL, Sun Y, Foreman KE, Nickoloff BJ, Nabel GJ. Distinct biology of Kaposi's sarcoma-associated herpesvirus from primary lesions and body cavity lymphomas. Journal of Virology. 72: 10073-82. PMID 9811747 DOI: 10.1128/Jvi.72.12.10073-10082.1998 |
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| 1998 |
Verma S, Woffendin C, Bahner I, Ranga U, Xu L, Yang ZY, King SR, Kohn DB, Nabel GJ. Gene transfer into human umbilical cord blood-derived CD34+ cells by particle-mediated gene transfer Gene Therapy. 5: 692-699. PMID 9797875 DOI: 10.1038/Sj.Gt.3300656 |
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| 1998 |
Chan SY, Louie MC, Piccotti JR, Iyer G, Ling X, Yang ZY, Nabel GJ, Bishop DK. Genetic vaccination-induced immune responses to the human immunodeficiency virus protein Rev: emergence of the interleukin 2-producing helper T lymphocyte. Human Gene Therapy. 9: 2187-96. PMID 9794203 DOI: 10.1089/Hum.1998.9.15-2187 |
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| 1998 |
Danthinne X, Aoki K, Kurachi AL, Nabel GJ, Nabel EG. Combination gene delivery of the cell cycle inhibitor p27 with thymidine kinase enhances prodrug cytotoxicity. Journal of Virology. 72: 9201-7. PMID 9765467 DOI: 10.1128/Jvi.72.11.9201-9207.1998 |
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| 1998 |
Hottiger MO, Nabel GJ. Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein. Journal of Virology. 72: 8252-6. PMID 9733868 DOI: 10.1128/Jvi.72.10.8252-8256.1998 |
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| 1998 |
Rekhter MD, Simari RD, Work CW, Nabel GJ, Nabel EG, Gordon D. Gene transfer into normal and atherosclerotic human blood vessels. Circulation Research. 82: 1243-52. PMID 9648720 DOI: 10.1161/01.Res.82.12.1243 |
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| 1998 |
Hottiger MO, Felzien LK, Nabel GJ. Modulation of cytokine-induced HIV gene expression by competitive binding of transcription factors to the coactivator p300. The Embo Journal. 17: 3124-34. PMID 9606194 DOI: 10.1093/Emboj/17.11.3124 |
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| 1998 |
Felzien LK, Woffendin C, Hottiger MO, Subbramanian RA, Cohen EA, Nabel GJ. HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator. Proceedings of the National Academy of Sciences of the United States of America. 95: 5281-6. PMID 9560267 DOI: 10.1073/Pnas.95.9.5281 |
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| 1998 |
Yang Z, Delgado R, Xu L, Todd RF, Nabel EG, Sanchez A, Nabel GJ. Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteins. Science (New York, N.Y.). 279: 1034-7. PMID 9461435 DOI: 10.1126/Science.279.5353.1034 |
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| 1998 |
Ranga U, Woffendin C, Verma S, Xu L, June CH, Bishop DK, Nabel GJ. Enhanced T cell engraftment after retroviral delivery of an antiviral gene in HIV-infected individuals. Proceedings of the National Academy of Sciences of the United States of America. 95: 1201-6. PMID 9448309 DOI: 10.1073/Pnas.95.3.1201 |
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| 1998 |
Xu L, Sanchez A, Yang Z, Zaki SR, Nabel EG, Nichol ST, Nabel GJ. Immunization for Ebola virus infection. Nature Medicine. 4: 37-42. PMID 9427604 DOI: 10.1038/nm0198-037 |
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| 1998 |
Arai H, Gordon D, Nabel EG, Nabel GJ. Gene transfer of Fas ligand induces tumor regression in vivo. Proceedings of the National Academy of Sciences of the United States of America. 94: 13862-7. PMID 9391118 DOI: 10.1073/Pnas.94.25.13862 |
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| 1998 |
Simari RD, Yang Z, Ling X, Stephan D, Perkins ND, Nabel GJ, Nabel EG. Requirements for Enhanced Transgene Expression by Untranslated Sequences from the Human Cytomegalovirus Immediate-Early Gene Molecular Medicine. 4: 700-706. DOI: 10.1007/Bf03401764 |
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| 1997 |
Li Z, Nabel GJ. A new member of the I kappaB protein family, I kappaB epsilon, inhibits RelA (p65)-mediated NF-kappaB transcription. Molecular and Cellular Biology. 17: 6184-90. PMID 9315679 DOI: 10.1128/Mcb.17.10.6184 |
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| 1997 |
Arai H, Chan SY, Bishop DK, Nabel GJ. Inhibition of the alloantibody response by CD95 ligand. Nature Medicine. 3: 843-8. PMID 9256273 DOI: 10.1038/Nm0897-843 |
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| 1997 |
Ohno T, Yang Z, Ling X, Jaffe M, Nabel EG, Normolle D, Nabel GJ. Combination gene transfer to potentiate tumor regression. Gene Therapy. 4: 361-6. PMID 9176523 DOI: 10.1038/Sj.Gt.3300403 |
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| 1997 |
Flowers CC, Woffendin C, Petryniak J, Yang S, Nabel GJ. Inhibition of recombinant human immunodeficiency virus type 1 replication by a site-specific recombinase. Journal of Virology. 71: 2685-92. PMID 9060621 DOI: 10.1128/Jvi.71.4.2685-2692.1997 |
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| 1997 |
Chinnaiyan AM, Woffendin C, Dixit VM, Nabel GJ. The inhibition of pro-apoptotic ICE-like proteases enhances HIV replication Nature Medicine. 3: 333-337. PMID 9055863 DOI: 10.1038/Nm0397-333 |
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| 1997 |
Parker SF, Felzien LK, Perkins ND, Imperiale MJ, Nabel GJ. Distinct domains of adenovirus E1A interact with specific cellular factors to differentially modulate human immunodeficiency virus transcription. Journal of Virology. 71: 2004-12. PMID 9032332 DOI: 10.1128/Jvi.71.3.2004-2012.1997 |
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| 1997 |
Ranga U, Woffendin C, Yang ZY, Xu L, Verma S, Littman DR, Nabel GJ. Cell and viral regulatory elements enhance the expression and function of a human immunodeficiency virus inhibitory gene. Journal of Virology. 71: 7020-7029. DOI: 10.1128/Jvi.71.9.7020-7029.1997 |
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| 1996 |
Nabel GJ, Gordon D, Bishop DK, Nickoloff BJ, Yang ZY, Aruga A, Cameron MJ, Nabel EG, Chang AE. Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA-liposome complexes. Proceedings of the National Academy of Sciences of the United States of America. 93: 15388-93. PMID 8986821 DOI: 10.1073/Pnas.93.26.15388 |
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| 1996 |
Parker SF, Perkins ND, Gitlin SD, Nabel GJ. A cooperative interaction of human T-cell leukemia virus type 1 Tax with the p21 cyclin-dependent kinase inhibitor activates the human immunodeficiency virus type 1 enhancer. Journal of Virology. 70: 5731-4. PMID 8764097 DOI: 10.1128/Jvi.70.8.5731-5734.1996 |
0.385 |
|
| 1996 |
Simari RD, San H, Rekhter M, Ohno T, Gordon D, Nabel GJ, Nabel EG. Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries. The Journal of Clinical Investigation. 98: 225-35. PMID 8690797 DOI: 10.1172/Jci118770 |
0.302 |
|
| 1996 |
Woffendin C, Ranga U, Yang Z, Xu L, Nabel GJ. Expression of a protective gene-prolongs survival of T cells in human immunodeficiency virus-infected patients. Proceedings of the National Academy of Sciences of the United States of America. 93: 2889-94. PMID 8610137 DOI: 10.1073/Pnas.93.7.2889 |
0.397 |
|
| 1996 |
Nabel GJ, Yang ZY, Nabel EG, Bishop K, Marquet M, Felgner PL, Gordon D, Chang AE. Direct gene transfer for treatment of human cancer. Annals of the New York Academy of Sciences. 772: 227-31. PMID 8546397 DOI: 10.1111/J.1749-6632.1995.Tb44748.X |
0.372 |
|
| 1996 |
Yang ZY, Perkins ND, Ohno T, Nabel EG, Nabel GJ. The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo. Nature Medicine. 1: 1052-6. PMID 7489362 DOI: 10.1038/Nm1095-1052 |
0.3 |
|
| 1996 |
Pompili VJ, Gordon D, San H, Yang Z, Muller DW, Nabel GJ, Nabel EG. Expression and function of a recombinant PDGF B gene in porcine arteries. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2254-64. PMID 7489251 DOI: 10.1161/01.Atv.15.12.2254 |
0.312 |
|
| 1996 |
Jaffe ML, Arai H, Nabel GJ. Mechanisms of Tumor-Induced Immunosuppression: Evidence for Contact-Dependent T Cell Suppression by Monocytes Molecular Medicine. 2: 692-701. DOI: 10.1007/Bf03401653 |
0.308 |
|
| 1995 |
Wu BY, Woffendin C, Duckett CS, Ohno T, Nabel GJ. Regulation of human retroviral latency by the NF-kappa B/I kappa B family: inhibition of human immunodeficiency virus replication by I kappa B through a Rev-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 92: 1480-4. PMID 7878004 DOI: 10.1073/Pnas.92.5.1480 |
0.399 |
|
| 1995 |
Duckett CS, Perkins ND, Leung K, Agranoff AB, Nabel GJ. Cytokine induction of nuclear factor kappa B in cycling and growth-arrested cells. Evidence for cell cycle-independent activation. The Journal of Biological Chemistry. 270: 18836-40. PMID 7642536 DOI: 10.1074/Jbc.270.32.18836 |
0.306 |
|
| 1995 |
Fox BA, Woffendin C, Yang ZY, San H, Ranga U, Gordon D, Osterholzer J, Nabel GJ. Genetic modification of human peripheral blood lymphocytes with a transdominant negative form of Rev: safety and toxicity. Human Gene Therapy. 6: 997-1004. PMID 7578421 DOI: 10.1089/Hum.1995.6.8-997 |
0.368 |
|
| 1994 |
Nabel GJ, Nabel EG, Yang ZY, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proceedings of the National Academy of Sciences of the United States of America. 90: 11307-11. PMID 8248244 DOI: 10.1073/Pnas.90.23.11307 |
0.34 |
|
| 1994 |
Hannibal MC, Markovitz DM, Nabel GJ. Multiple cis-acting elements in the human immunodeficiency virus type 2 enhancer mediate the response to T-cell receptor stimulation by antigen in a T-cell hybridoma line Blood. 83: 1839-1846. PMID 8142652 DOI: 10.1182/Blood.V83.7.1839.Bloodjournal8371839 |
0.418 |
|
| 1994 |
Perkins ND, Agranoff AB, Duckett CS, Nabel GJ. Transcription factor AP-2 regulates human immunodeficiency virus type 1 gene expression. Journal of Virology. 68: 6820-3. PMID 8084021 DOI: 10.1128/Jvi.68.10.6820-6823.1994 |
0.373 |
|
| 1994 |
Plautz GE, Nabel EG, Fox B, Yang ZY, Jaffe M, Gordon D, Chang A, Nabel GJ. Direct gene transfer for the understanding and treatment of human disease. Annals of the New York Academy of Sciences. 716: 144-53. PMID 8024191 DOI: 10.1111/J.1749-6632.1994.Tb21709.X |
0.327 |
|
| 1994 |
Nabel EG, Plautz GE, Nabel GJ. Recombinant growth factor gene expression in vascular cells in vivo. Annals of the New York Academy of Sciences. 714: 247-52. PMID 8017774 DOI: 10.1111/J.1749-6632.1994.Tb12050.X |
0.34 |
|
| 1994 |
Nabel EG, Nabel GJ. Complex models for the study of gene function in cardiovascular biology. Annual Review of Physiology. 56: 741-61. PMID 8010759 DOI: 10.1146/Annurev.Ph.56.030194.003521 |
0.318 |
|
| 1994 |
Woffendin C, Yang ZY, Udaykumar, Xu L, Yang NS, Sheehy MJ, Nabel GJ. Nonviral and viral delivery of a human immunodeficiency virus protective gene into primary human T cells Proceedings of the National Academy of Sciences of the United States of America. 91: 11581-11585. PMID 7972106 DOI: 10.1073/Pnas.91.24.11581 |
0.428 |
|
| 1994 |
Perkins ND, Agranoff AB, Pascal E, Nabel GJ. An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation. Molecular and Cellular Biology. 14: 6570-83. PMID 7935378 DOI: 10.1128/Mcb.14.10.6570 |
0.38 |
|
| 1994 |
Hannibal M, Markovitz D, Nabel G. Multiple cis-acting elements in the human immunodeficiency virus type 2 enhancer mediate the response to T-cell receptor stimulation by antigen in a T-cell hybridoma line Blood. 83: 1839-1846. DOI: 10.1182/blood.v83.7.1839.1839 |
0.305 |
|
| 1993 |
Plautz GE, Yang ZY, Wu BY, Gao X, Huang L, Nabel GJ. Immunotherapy of malignancy by in vivo gene transfer into tumors. Proceedings of the National Academy of Sciences of the United States of America. 90: 4645-9. PMID 8506311 DOI: 10.1089/Hum.1992.3.4-399 |
0.336 |
|
| 1993 |
Nabel EG, Yang Z, Liptay S, San H, Gordon D, Haudenschild CC, Nabel GJ. Recombinant platelet-derived growth factor B gene expression in porcine arteries induce intimal hyperplasia in vivo. The Journal of Clinical Investigation. 91: 1822-9. PMID 8473521 DOI: 10.1172/Jci116394 |
0.307 |
|
| 1993 |
Butera ST, Roberts BD, Leung K, Nabel GJ, Folks TM. Tumor necrosis factor receptor expression and signal transduction in HIV-1-infected cells. Aids (London, England). 7: 911-8. PMID 8395188 DOI: 10.1097/00002030-199307000-00002 |
0.351 |
|
| 1993 |
Hannibal MC, Markovitz DM, Clark N, Nabel GJ. Differential activation of human immunodeficiency virus type 1 and 2 transcription by specific T-cell activation signals Journal of Virology. 67: 5035-5040. PMID 8331739 DOI: 10.1128/Jvi.67.8.5035-5040.1993 |
0.403 |
|
| 1993 |
Eck SL, Perkins ND, Carr DP, Nabel GJ. Inhibition of phorbol ester-induced cellular adhesion by competitive binding of NF-kappa B in vivo. Molecular and Cellular Biology. 13: 6530-6. PMID 8105372 DOI: 10.1128/Mcb.13.10.6530 |
0.316 |
|
| 1993 |
Nabel GJ, Felgner PL. Direct gene transfer for immunotherapy and immunization. Trends in Biotechnology. 11: 211-5. PMID 7763814 DOI: 10.1016/0167-7799(93)90117-R |
0.432 |
|
| 1993 |
Shu HB, Agranoff AB, Nabel EG, Leung K, Duckett CS, Neish AS, Collins T, Nabel GJ. Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells. Molecular and Cellular Biology. 13: 6283-9. PMID 7692229 DOI: 10.1128/Mcb.13.10.6283 |
0.318 |
|
| 1993 |
Nabel EG, Gordon D, Yang ZY, Xu L, San H, Plautz GE, Wu BY, Gao X, Huang L, Nabel GJ. Gene transfer in vivo with DNA-liposome complexes: lack of autoimmunity and gonadal localization. Human Gene Therapy. 3: 649-56. PMID 1482705 DOI: 10.1089/Hum.1992.3.6-649 |
0.315 |
|
| 1993 |
Perkins N, Edwards N, Duckett C, Agranoff A, Schmid R, Nabel G. A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation. The Embo Journal. 12: 3551-3558. DOI: 10.1002/J.1460-2075.1993.Tb06029.X |
0.357 |
|
| 1992 |
Krasnow SW, Zhang LQ, Leung KY, Osborn L, Kunkel S, Nabel GJ. Tumor necrosis factor-alpha, interleukin 1, and phorbol myristate acetate are independent activators of NF-kappa B which differentially activate T cells. Cytokine. 3: 372-9. PMID 1751774 DOI: 10.1016/1043-4666(91)90040-K |
0.308 |
|
| 1992 |
Nabel EG, Plautz G, Nabel GJ. Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis. Proceedings of the National Academy of Sciences of the United States of America. 89: 5157-61. PMID 1594626 DOI: 10.1073/Pnas.89.11.5157 |
0.337 |
|
| 1992 |
Liu J, Perkins ND, Schmid RM, Nabel GJ. Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription. Journal of Virology. 66: 3883-7. PMID 1583734 DOI: 10.1128/Jvi.66.6.3883-3887.1992 |
0.394 |
|
| 1992 |
Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B, Leiden JM. cis-Acting Sequences Required for Inducible Interleukin-2 Enhancer Function Bind a Novel Ets-Related Protein, Elf-1 Molecular and Cellular Biology. 12: 1043-1053. PMID 1545787 DOI: 10.1128/Mcb.12.3.1043 |
0.338 |
|
| 1992 |
Perkins ND, Schmid RM, Duckett CS, Leung K, Rice NR, Nabel GJ. Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation. Proceedings of the National Academy of Sciences of the United States of America. 89: 1529-33. PMID 1542644 DOI: 10.1073/Pnas.89.5.1529 |
0.307 |
|
| 1992 |
Markovitz DM, Hannibal MC, Smith MJ, Cossman R, Nabel GJ. Activation of the human immunodeficiency virus type 1 enhancer is not dependent on NFAT-1 Journal of Virology. 66: 3961-3965. PMID 1533884 DOI: 10.1128/Jvi.66.6.3961-3965.1992 |
0.377 |
|
| 1992 |
Leiden JM, Wang CY, Petryniak B, Markovitz DM, Nabel GJ, Thompson CB. A novel Ets-related transcription factor, Elf-1, binds to human immunodeficiency virus type 2 regulatory elements that are required for inducible trans activation in T cells. Journal of Virology. 66: 5890-7. PMID 1527846 DOI: 10.1128/Jvi.66.10.5890-5897.1992 |
0.406 |
|
| 1992 |
Markovitz DM, Smith MJ, Hilfinger J, Hannibal MC, Petryniak B, Nabel GJ. Activation of the human immunodeficiency virus type 2 enhancer is dependent on purine box and κB regulatory elements Journal of Virology. 66: 5479-5484. PMID 1501284 DOI: 10.1128/Jvi.66.9.5479-5484.1992 |
0.389 |
|
| 1992 |
Malim MH, Freimuth WW, Liu J, Boyle TJ, Lyerly HK, Cullen BR, Nabel GJ. Stable expression of transdominant rev protein in human T cells inhibits human immunodeficiency virus replication Journal of Experimental Medicine. 176: 1197-1201. PMID 1402661 DOI: 10.1084/Jem.176.4.1197 |
0.42 |
|
| 1992 |
Wu B, Hanley E, Turka L, Nabel G. Isolation of a cDNA clone encoding a zinc finger protein highly expressed in T-leukemia lines Blood. 80: 2571-2576. DOI: 10.1182/Blood.V80.10.2571.Bloodjournal80102571 |
0.308 |
|
| 1991 |
Nabel GJ. HIV. Tampering with transcription. Nature. 350: 658. PMID 2023629 DOI: 10.1038/350658A0 |
0.337 |
|
| 1991 |
Nabel EG, Plautz G, Nabel GJ. Gene transfer into vascular cells. Journal of the American College of Cardiology. 17: 189B-194B. PMID 2016477 DOI: 10.1016/0735-1097(91)90957-B |
0.318 |
|
| 1991 |
Griffin GE, Leung K, Folks TM, Kunkel S, Nabel GJ. Induction of NF-χB during monocyte differentiation is associated with activation of HIV-gene expression Research in Virology. 142: 233-238. PMID 1896645 DOI: 10.1016/0923-2516(91)90062-8 |
0.389 |
|
| 1991 |
Schmid RM, Perkins ND, Duckett CS, Andrews PC, Nabel GJ. Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65. Nature. 352: 733-6. PMID 1876189 DOI: 10.1038/352733A0 |
0.337 |
|
| 1991 |
Butera ST, Perez VL, Wu BY, Nabel GJ, Folks TM. Oscillation of the human immunodeficiency virus surface receptor is regulated by the state of viral activation in a CD4+ cell model of chronic infection. Journal of Virology. 65: 4645-53. PMID 1678437 DOI: 10.1128/Jvi.65.9.4645-4653.1991 |
0.362 |
|
| 1991 |
Baier L, Hannibal M, Hanley E, Nabel G. Lymphoid expression and TATAA binding of a human protein containing an Antennapedia homeodomain Blood. 78: 1047-1055. DOI: 10.1182/Blood.V78.4.1047.Bloodjournal7841047 |
0.338 |
|
| 1991 |
Nabel GJ, Nabel EG. Chapter 32. Perspectives on Human Gene Therapy Annual Reports in Medicinal Chemistry. 26: 315-319. DOI: 10.1016/S0065-7743(08)61219-1 |
0.315 |
|
| 1990 |
Bielinska A, Shivdasani RA, Zhang LQ, Nabel GJ. Regulation of gene expression with double-stranded phosphorothioate oligonucleotides. Science (New York, N.Y.). 250: 997-1000. PMID 2237444 DOI: 10.1126/Science.2237444 |
0.388 |
|
| 1990 |
Markovitz DM, Hannibal M, Perez VL, Gauntt C, Folks TM, Nabel GJ. Differential regulation of human immunodeficiency viruses (HIVs): A specific regulatory element in HIV-2 responds to stimulation of the T-cell antigen receptor Proceedings of the National Academy of Sciences of the United States of America. 87: 9098-9102. PMID 2147512 DOI: 10.1073/Pnas.87.23.9098 |
0.395 |
|
| 1990 |
Nabel EG, Plautz G, Nabel GJ. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science (New York, N.Y.). 249: 1285-8. PMID 2119055 DOI: 10.1126/Science.2119055 |
0.345 |
|
| 1990 |
GRIFFIN G, LEUNG K, FOLKS T, KUNKEL S, NABEL G. NF-K B and HIV Nature. 343: 219-219. DOI: 10.1038/343219A0 |
0.311 |
|
| 1989 |
Griffin GE, Leung K, Folks TM, Kunkel S, Nabel GJ. Activation of HIV gene expression during monocyte differentiation by induction of NF-kB Nature. 339: 70-73. PMID 2654643 DOI: 10.1038/339070A0 |
0.409 |
|
| 1989 |
Bielinska A, Krasnow S, Nabel GJ. NF-kappa B-mediated activation of the human immunodeficiency virus enhancer: site of transcriptional initiation is independent of the TATA box. Journal of Virology. 63: 4097-100. PMID 2527315 DOI: 10.1128/Jvi.63.9.4097-4100.1989 |
0.387 |
|
| 1989 |
Osborn L, Kunkel S, Nabel GJ. Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proceedings of the National Academy of Sciences of the United States of America. 86: 2336-40. PMID 2494664 DOI: 10.1073/Pnas.86.7.2336 |
0.365 |
|
| 1988 |
Leung K, Nabel GJ. HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-kappa B-like factor. Nature. 333: 776-8. PMID 2838755 DOI: 10.1038/333776A0 |
0.369 |
|
| 1988 |
Nabel GJ, Rice SA, Knipe DM, Baltimore D. Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells Science. 239: 1299-1302. PMID 2830675 DOI: 10.1126/Science.2830675 |
0.444 |
|
| 1988 |
Nabel GJ. Activation of human immunodeficiency virus. Journal of Laboratory and Clinical Medicine. 111: 495-500. DOI: 10.5555/Uri:Pii:002221438890073X |
0.334 |
|
| 1987 |
Nabel G, Baltimore D. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature. 326: 711-3. PMID 3031512 DOI: 10.1038/326711A0 |
0.437 |
|
| 1982 |
Galli SJ, Dvorak AM, Ishizaka T, Nabel G, Der Simonian H, Cantor H, Dvorak HF. A cloned cell with NK function resembles basophils by ultrastructure and expresses IgE receptors. Nature. 298: 288-90. PMID 6211628 DOI: 10.1038/298288A0 |
0.307 |
|
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