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Stuart Milstein, Ph.D. - Publications

Affiliations: 
2001 Stony Brook University, Stony Brook, NY, United States 
Area:
Genetics, Animal Physiology Biology
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mancio-Silva L, Fleming HE, Miller AB, Milstein S, Liebow A, Haslett P, Sepp-Lorenzino L, Bhatia SN. Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers. Cell Metabolism. 29: 727-735.e3. PMID 30840913 DOI: 10.1016/J.Cmet.2019.02.003  0.334
2018 Foster DJ, Brown CR, Shaikh S, Trapp C, Schlegel MK, Qian K, Sehgal A, Rajeev KG, Jadhav V, Manoharan M, Kuchimanchi S, Maier MA, Milstein S. Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29456020 DOI: 10.1016/J.Ymthe.2017.12.021  0.325
2017 Singh KD, Zheng X, Milstein S, Keller M, Roschitzki B, Grossmann J, Hengartner MO. Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans. Plos One. 12: e0182270. PMID 28759574 DOI: 10.1371/journal.pone.0182270  0.482
2017 Milstein S, Qian K, Zhang L, Sehgal A. Methods to Identify and Characterize siRNAs Targeting Serpin A1 In Vitro and In Vivo Using RNA Interference. Methods in Molecular Biology (Clifton, N.J.). 1639: 115-126. PMID 28752451 DOI: 10.1007/978-1-4939-7163-3_11  0.302
2016 Butler JS, Chan A, Costelha S, Fishman S, Willoughby JL, Borland TD, Milstein S, Foster DJ, Gonçalves P, Chen Q, Qin J, Bettencourt BR, Sah DW, Alvarez R, Rajeev KG, et al. Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-10. PMID 27033334 DOI: 10.3109/13506129.2016.1160882  0.313
2015 Chan A, Liebow A, Yasuda M, Gan L, Racie T, Maier M, Kuchimanchi S, Foster D, Milstein S, Charisse K, Sehgal A, Manoharan M, Meyers R, Fitzgerald K, Simon A, et al. Preclinical Development of a Subcutaneous ALAS1 RNAi Therapeutic for Treatment of Hepatic Porphyrias Using Circulating RNA Quantification. Molecular Therapy. Nucleic Acids. 4: e263. PMID 26528940 DOI: 10.1038/Mtna.2015.36  0.317
2015 Rajeev KG, Nair JK, Jayaraman M, Charisse K, Taneja N, O'Shea J, Willoughby JL, Yucius K, Nguyen T, Shulga-Morskaya S, Milstein S, Liebow A, Querbes W, Borodovsky A, Fitzgerald K, et al. Hepatocyte-specific delivery of siRNAs conjugated to novel non-nucleosidic trivalent N-acetylgalactosamine elicits robust gene silencing in vivo. Chembiochem : a European Journal of Chemical Biology. 16: 903-8. PMID 25786782 DOI: 10.1002/Cbic.201500023  0.321
2015 Matsuda S, Keiser K, Nair JK, Charisse K, Manoharan RM, Kretschmer P, Peng CG, V Kel'in A, Kandasamy P, Willoughby JL, Liebow A, Querbes W, Yucius K, Nguyen T, Milstein S, et al. siRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytes. Acs Chemical Biology. 10: 1181-7. PMID 25730476 DOI: 10.1021/Cb501028C  0.313
2015 Rajeev KG, Nair JK, Jayaraman M, Charisse K, Taneja N, O'Shea J, Willoughby JLS, Yucius K, Nguyen T, Shulga-Morskaya S, Milstein S, Liebow A, Querbes W, Borodovsky A, Fitzgerald K, et al. Cover Picture: Hepatocyte-Specific Delivery of siRNAs Conjugated to Novel Non-nucleosidic TrivalentN-Acetylgalactosamine Elicits Robust Gene Silencing in Vivo (ChemBioChem 6/2015) Chembiochem. 16: 873-873. DOI: 10.1002/Cbic.201590012  0.312
2014 Nair JK, Willoughby JL, Chan A, Charisse K, Alam MR, Wang Q, Hoekstra M, Kandasamy P, Kel'in AV, Milstein S, Taneja N, O'Shea J, Shaikh S, Zhang L, van der Sluis RJ, et al. Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing. Journal of the American Chemical Society. 136: 16958-61. PMID 25434769 DOI: 10.1021/Ja505986A  0.321
2013 Tummala S, Titus M, Wilson L, Wang C, Ciatto C, Thill G, Foster D, Li C, Szabo Z, Guttman A, Bettencourt B, Jayaraman M, Deroot J, Kocisko D, Pollard S, ... ... Milstein S, et al. Evaluation of exogenous siRNA addition as a metabolic engineering tool for modifying biopharmaceuticals. Biotechnology Progress. 29: 415-24. PMID 23172735 DOI: 10.1002/Btpr.1667  0.332
2012 Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, et al. Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Molecular Therapy. Nucleic Acids. 1: e4. PMID 23344621 DOI: 10.1038/Mtna.2011.3  0.349
2011 Toudjarska I, Cai Z, Racie T, Hettinger J, Milstein S, Bettencourt BR, Sah DW, Bumcrot D, Maraganore J, Vaishnaw A. RNAi-Mediated Inhibition of Activated Protein C- A New Approach for Hemophilia Treatment Blood. 118: 1204-1204. DOI: 10.1182/Blood.V118.21.1204.1204  0.36
2009 Dreze M, Charloteaux B, Milstein S, Vidalain PO, Yildirim MA, Zhong Q, Svrzikapa N, Romero V, Laloux G, Brasseur R, Vandenhaute J, Boxem M, Cusick ME, Hill DE, Vidal M. 'Edgetic' perturbation of a C. elegans BCL2 ortholog. Nature Methods. 6: 843-9. PMID 19855391 DOI: 10.1038/Nmeth.1394  0.332
2009 Salehi-Ashtiani K, Lin C, Hao T, Shen Y, Szeto D, Yang X, Ghamsari L, Lee H, Fan C, Murray RR, Milstein S, Svrzikapa N, Cusick ME, Roth FP, Hill DE, et al. Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome. Genome Research. 19: 2334-42. PMID 19801531 DOI: 10.1101/Gr.098640.109  0.305
2009 Simonis N, Rual JF, Carvunis AR, Tasan M, Lemmens I, Hirozane-Kishikawa T, Hao T, Sahalie JM, Venkatesan K, Gebreab F, Cevik S, Klitgord N, Fan C, Braun P, Li N, ... ... Milstein S, et al. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Nature Methods. 6: 47-54. PMID 19123269 DOI: 10.1038/Nmeth.1279  0.303
2008 Boxem M, Maliga Z, Klitgord N, Li N, Lemmens I, Mana M, de Lichtervelde L, Mul JD, van de Peut D, Devos M, Simonis N, Yildirim MA, Cokol M, Kao HL, de Smet AS, ... ... Milstein S, et al. A protein domain-based interactome network for C. elegans early embryogenesis. Cell. 134: 534-45. PMID 18692475 DOI: 10.1016/J.Cell.2008.07.009  0.303
2006 Kritikou EA, Milstein S, Vidalain PO, Lettre G, Bogan E, Doukoumetzidis K, Gray P, Chappell TG, Vidal M, Hengartner MO. C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival. Genes & Development. 20: 2279-92. PMID 16912277 DOI: 10.1101/Gad.384506  0.531
2002 Hofmann ER, Milstein S, Boulton SJ, Ye M, Hofmann JJ, Stergiou L, Gartner A, Vidal M, Hengartner MO. Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Current Biology : Cb. 12: 1908-18. PMID 12445383 DOI: 10.1016/S0960-9822(02)01262-9  0.507
2000 Hofmann ER, Milstein S, Hengartner MO. DNA-damage-induced checkpoint pathways in the nematode Caenorhabditis elegans. Cold Spring Harbor Symposia On Quantitative Biology. 65: 467-73. PMID 12760063  0.444
2000 Gartner A, Milstein S, Ahmed S, Hodgkin J, Hengartner MO. A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans. Molecular Cell. 5: 435-43. PMID 10882129 DOI: 10.1016/S1097-2765(00)80438-4  0.531
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