| Year |
Citation |
Score |
| 2014 |
Salvador LA, Park H, Al-Awadhi FH, Liu Y, Kim B, Zeller SL, Chen QY, Hong J, Luesch H. Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties. Acs Medicinal Chemistry Letters. 5: 905-10. PMID 25147612 DOI: 10.1021/Ml500170R |
0.734 |
|
| 2014 |
Kim B, Park H, Salvador LA, Serrano PE, Kwan JC, Zeller SL, Chen QY, Ryu S, Liu Y, Byeon S, Luesch H, Hong J. Evaluation of class I HDAC isoform selectivity of largazole analogues. Bioorganic & Medicinal Chemistry Letters. 24: 3728-31. PMID 25070421 DOI: 10.1016/J.Bmcl.2014.07.006 |
0.739 |
|
| 2014 |
Chen QY, Liu Y, Cai W, Luesch H. Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity. Journal of Medicinal Chemistry. 57: 3011-29. PMID 24660812 DOI: 10.1021/Jm4019965 |
0.767 |
|
| 2014 |
Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H. Largazole pharmacokinetics in rats by LC-MS/MS. Marine Drugs. 12: 1623-40. PMID 24658499 DOI: 10.3390/Md12031623 |
0.702 |
|
| 2014 |
Kwan JC, Liu Y, Ratnayake R, Hatano R, Kuribara A, Morimoto C, Ohnuma K, Paul VJ, Ye T, Luesch H. Grassypeptolides as natural inhibitors of dipeptidyl peptidase 8 and T-cell activation. Chembiochem : a European Journal of Chemical Biology. 15: 799-804. PMID 24591193 DOI: 10.1002/Cbic.201300762 |
0.787 |
|
| 2013 |
Ratnayake R, Liu Y, Paul VJ, Luesch H. Cultivated sea lettuce is a multiorgan protector from oxidative and inflammatory stress by enhancing the endogenous antioxidant defense system. Cancer Prevention Research (Philadelphia, Pa.). 6: 989-99. PMID 24005795 DOI: 10.1158/1940-6207.Capr-13-0014 |
0.741 |
|
| 2013 |
Liu H, Liu Y, Wang Z, Xing X, Maguire AR, Luesch H, Zhang H, Xu Z, Ye T. Total synthesis and biological evaluation of grassypeptolide A. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 6774-84. PMID 23536467 DOI: 10.1002/Chem.201203667 |
0.544 |
|
| 2013 |
Gupta E, Santos N, Liu Y, Havre P, Dang NH, Luesch H, Dang LH. Targeting HIF-1α and HIF-2α to Overcome Treatment Resistance Mediated by Oncogenic KRAS in Colorectal Cancer Journal of Cancer Therapy. 4: 1132-1139. DOI: 10.4236/Jct.2013.46129 |
0.59 |
|
| 2012 |
Liu Y, Zhang W, Li L, Salvador LA, Chen T, Chen W, Felsenstein KM, Ladd TB, Price AR, Golde TE, He J, Xu Y, Li Y, Luesch H. Cyanobacterial peptides as a prototype for the design of potent β-secretase inhibitors and the development of selective chemical probes for other aspartic proteases. Journal of Medicinal Chemistry. 55: 10749-65. PMID 23181502 DOI: 10.1021/Jm301630S |
0.785 |
|
| 2012 |
Yang S, Zhang W, Ding N, Lo J, Liu Y, Clare-Salzler MJ, Luesch H, Li Y. Total synthesis of grassystatin A, a probe for cathepsin E function. Bioorganic & Medicinal Chemistry. 20: 4774-80. PMID 22748705 DOI: 10.1016/J.Bmc.2012.05.077 |
0.58 |
|
| 2011 |
Santos N, Wenger JB, Havre P, Liu Y, Dagan R, Imanirad I, Ivey AM, Zlotecki RA, Algood CB, Gilbert SM, Allegra CJ, Okunieff P, Vieweg J, Dang NH, Luesch H, et al. Combination therapy for renal cell cancer: What are possible options? Oncology. 81: 220-229. PMID 22085914 DOI: 10.1159/000333470 |
0.569 |
|
| 2011 |
Chen QY, Liu Y, Luesch H. Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity. Acs Medicinal Chemistry Letters. 2: 861-865. PMID 22081789 DOI: 10.1021/Ml200176M |
0.779 |
|
| 2011 |
Wenger JB, Santos N, Liu Y, Dallas J, Subbiah S, Hochwald S, Huang EH, Dang DT, Allegra CJ, Luesch H, Dang LH. Can we develop effective combination antiangiogenic therapy for patients with hepatocellular carcinoma? Oncology Reviews. 5: 177-184. PMID 21949574 DOI: 10.1007/S12156-011-0082-3 |
0.528 |
|
| 2011 |
Meickle T, Gunasekera SP, Liu Y, Luesch H, Paul VJ. Porpoisamides A and B, two novel epimeric cyclic depsipeptides from a Florida Keys collection of Lyngbya sp. Bioorganic & Medicinal Chemistry. 19: 6576-80. PMID 21705224 DOI: 10.1016/J.Bmc.2011.05.051 |
0.566 |
|
| 2010 |
Liu Y, Salvador LA, Byeon S, Ying Y, Kwan JC, Law BK, Hong J, Luesch H. Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor. The Journal of Pharmacology and Experimental Therapeutics. 335: 351-61. PMID 20739454 DOI: 10.1124/Jpet.110.172387 |
0.776 |
|
| 2009 |
Taori K, Liu Y, Paul VJ, Luesch H. Combinatorial strategies by marine cyanobacteria: symplostatin 4, an antimitotic natural dolastatin 10/15 hybrid that synergizes with the coproduced HDAC inhibitor largazole. Chembiochem : a European Journal of Chemical Biology. 10: 1634-9. PMID 19514039 DOI: 10.1002/Cbic.200900192 |
0.774 |
|
| 2009 |
Schriner SE, Avanesian A, Liu Y, Luesch H, Jafari M. Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses. Free Radical Biology & Medicine. 47: 577-84. PMID 19486939 DOI: 10.1016/J.Freeradbiomed.2009.05.025 |
0.545 |
|
| 2009 |
Liu Y, Law BK, Luesch H. Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation. Molecular Pharmacology. 76: 91-104. PMID 19403701 DOI: 10.1124/Mol.109.056085 |
0.608 |
|
| 2008 |
Luesch H, Liu Y. Genome-wide overexpression screen for activators of antioxidant gene transcription. Methods in Molecular Biology (Clifton, N.J.). 477: 343-54. PMID 19082959 DOI: 10.1007/978-1-60327-517-0_26 |
0.555 |
|
| 2008 |
Ying Y, Liu Y, Byeon SR, Kim H, Luesch H, Hong J. Synthesis and activity of largazole analogues with linker and macrocycle modification. Organic Letters. 10: 4021-4. PMID 18707106 DOI: 10.1021/Ol801532S |
0.626 |
|
| 2007 |
Liu Y, Kern JT, Walker JR, Johnson JA, Schultz PG, Luesch H. A genomic screen for activators of the antioxidant response element. Proceedings of the National Academy of Sciences of the United States of America. 104: 5205-10. PMID 17360324 DOI: 10.1073/Pnas.0700898104 |
0.667 |
|
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