Bradley D. Gelfand, Ph.D. - Publications

Affiliations: 
2009 University of Virginia, Charlottesville, VA 
Area:
Biomedical Engineering

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Narendran S, Pereira F, Yerramothu P, Apicella I, Wang SB, Varshney A, Baker KL, Marion KM, Ambati M, Ambati VL, Ambati K, Sadda SR, Gelfand BD, Ambati J. A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration. Investigative Ophthalmology & Visual Science. 61: 4. PMID 32749462 DOI: 10.1167/Iovs.61.10.4  0.313
2020 Wright CB, Uehara H, Kim Y, Yasuma T, Yasuma R, Hirahara S, Makin RD, Apicella I, Pereira F, Nagasaka Y, Narendran S, Fukuda S, Albuquerque R, Fowler BJ, Bastos-Carvalho A, ... ... Gelfand BD, et al. Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 31964819 DOI: 10.1073/Pnas.1909761117  0.343
2018 Makin RD, Apicella I, Nagasaka Y, Kaneko H, Turner SD, Kerur N, Ambati J, Gelfand BD. RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes. Investigative Ophthalmology & Visual Science. 59: 5795-5802. PMID 30508043 DOI: 10.1167/Iovs.18-25215  0.315
2017 Kerur N, Fukuda S, Banerjee D, Kim Y, Fu D, Apicella I, Varshney A, Yasuma R, Fowler BJ, Baghdasaryan E, Marion KM, Huang X, Yasuma T, Hirano Y, Serbulea V, ... ... Gelfand BD, et al. cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature Medicine. PMID 29176737 DOI: 10.1038/Nm.4450  0.364
2016 Gelfand BD, Ambati J. A Revised Hemodynamic Theory of Age-Related Macular Degeneration. Trends in Molecular Medicine. PMID 27423265 DOI: 10.1016/J.Molmed.2016.06.009  0.332
2016 Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, ... ... Gelfand BD, et al. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduction and Targeted Therapy. 1. PMID 26925256 DOI: 10.1038/Sigtrans.2015.2  0.358
2016 Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, ... ... Gelfand BD, et al. Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal Transduction and Targeted Therapy. 1. PMID 26918197 DOI: 10.1038/Sigtrans.2015.1  0.375
2014 Fowler BJ, Gelfand BD, Kim Y, Kerur N, Tarallo V, Hirano Y, Amarnath S, Fowler DH, Radwan M, Young MT, Pittman K, Kubes P, Agarwal HK, Parang K, Hinton DR, et al. Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Science (New York, N.Y.). 346: 1000-3. PMID 25414314 DOI: 10.1126/Science.1261754  0.365
2014 Kim Y, Tarallo V, Kerur N, Yasuma T, Gelfand BD, Bastos-Carvalho A, Hirano Y, Yasuma R, Mizutani T, Fowler BJ, Li S, Kaneko H, Bogdanovich S, Ambati BK, Hinton DR, et al. DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 111: 16082-7. PMID 25349431 DOI: 10.1073/Pnas.1403814111  0.342
2013 Feaver RE, Gelfand BD, Blackman BR. Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells. Nature Communications. 4: 1525. PMID 23443553 DOI: 10.1038/Ncomms2530  0.673
2013 FOWLER B, KERUR N, GELFAND B, BASTOS-CARVALHO A, AMBATI J. Alu retrotransposon quantification in the retina and plasma: Mechanism-based risk assessment in age-related macular degeneration Acta Ophthalmologica. 91: 0-0. DOI: 10.1111/J.1755-3768.2013.T081.X  0.302
2013 BASTOS CARVALHO A, KERUR N, KIM Y, FOWLER B, GELFAND B, AMBATI J. Intercellular trafficking of Alu RNAs causes geographic atrophy expansion in AMD Acta Ophthalmologica. 91: 0-0. DOI: 10.1111/J.1755-3768.2013.F049.X  0.353
2013 GELFAND B, KIM Y, YASUMA T, LI S, FOWLER B, KLEINMAN M, AMABTI J. Iron antagonism of DICER1 promotes NLRP3 inflammasome priming due to enhanced Alu RNA stability Acta Ophthalmologica. 91: 0-0. DOI: 10.1111/J.1755-3768.2013.4771.X  0.326
2012 Dridi S, Hirano Y, Tarallo V, Kim Y, Fowler BJ, Ambati BK, Bogdanovich S, Chiodo VA, Hauswirth WW, Kugel JF, Goodrich JA, Ponicsan SL, Hinton DR, Kleinman ME, Baffi JZ, ... Gelfand BD, et al. ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America. 109: 13781-6. PMID 22869729 DOI: 10.1073/Pnas.1206494109  0.367
2012 Tarallo V, Hirano Y, Gelfand BD, Dridi S, Kerur N, Kim Y, Cho WG, Kaneko H, Fowler BJ, Bogdanovich S, Albuquerque RJ, Hauswirth WW, Chiodo VA, Kugel JF, Goodrich JA, et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell. 149: 847-59. PMID 22541070 DOI: 10.1016/J.Cell.2012.03.036  0.342
2012 Kleinman ME, Kaneko H, Cho WG, Dridi S, Fowler BJ, Blandford AD, Albuquerque RJ, Hirano Y, Terasaki H, Kondo M, Fujita T, Ambati BK, Tarallo V, Gelfand BD, Bogdanovich S, et al. Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 101-8. PMID 21988875 DOI: 10.1038/Mt.2011.212  0.381
2011 Gelfand BD, Meller J, Pryor AW, Kahn M, Bortz PD, Wamhoff BR, Blackman BR. Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1625-33. PMID 21527747 DOI: 10.1161/Atvbaha.111.227827  0.665
2011 Kaneko H, Dridi S, Tarallo V, Gelfand BD, Fowler BJ, Cho WG, Kleinman ME, Ponicsan SL, Hauswirth WW, Chiodo VA, Karikó K, Yoo JW, Lee DK, Hadziahmetovic M, Song Y, et al. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature. 471: 325-30. PMID 21297615 DOI: 10.1038/Nature09830  0.347
2010 Feaver RE, Gelfand BD, Wang C, Schwartz MA, Blackman BR. Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circulation Research. 106: 1703-11. PMID 20378855 DOI: 10.1161/Circresaha.109.216283  0.687
2008 Harry BL, Sanders JM, Feaver RE, Lansey M, Deem TL, Zarbock A, Bruce AC, Pryor AW, Gelfand BD, Blackman BR, Schwartz MA, Ley K. Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2003-8. PMID 18688018 DOI: 10.1161/Atvbaha.108.164707  0.674
2006 Gelfand BD, Epstein FH, Blackman BR. Spatial and spectral heterogeneity of time-varying shear stress profiles in the carotid bifurcation by phase-contrast MRI. Journal of Magnetic Resonance Imaging : Jmri. 24: 1386-92. PMID 17083089 DOI: 10.1002/Jmri.20765  0.651
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