Yuet-Kin Leung, Ph.D. - Publications

Affiliations: 
2001 The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Molecular Biology, Toxicology, Cell Biology, Pharmacology

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wongsurawat T, Jenjaroenpun P, De Loose A, Alkam D, Ussery DW, Nookaew I, Leung YK, Ho SM, Day JD, Rodriguez A. A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma. Acta Neuropathologica Communications. 8: 87. PMID 32563269 DOI: 10.1186/S40478-020-00963-0  0.302
2020 Lu Y, Liu X, Zhang E, Kopras EJ, Smith EP, Astreinidis A, Li C, Leung YK, Ho SM, Yu JJ. Estrogen activates pyruvate kinase M2 and increases the growth of TSC2-deficient cells. Plos One. 15: e0228894. PMID 32078667 DOI: 10.1371/Journal.Pone.0228894  0.334
2018 Leung YK, Ouyang B, Niu L, Xie C, Ying J, Medvedovic M, Chen A, Weihe P, Valvi D, Grandjean P, Ho SM. Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort. Epigenetics. 1-32. PMID 29560787 DOI: 10.1080/15592294.2018.1445901  0.308
2017 Khanal T, Choi K, Leung YK, Wang J, Kim D, Janakiram V, Cho SG, Puga A, Ho SM, Kim K. Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer. Scientific Reports. 7: 10662. PMID 28878246 DOI: 10.1038/S41598-017-11106-2  0.351
2017 Leung YK, Govindarajah V, Cheong A, Veevers J, Song D, Gear R, Zhu X, Ying J, Kendler A, Medvedovic M, Belcher S, Ho SM. Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk. Endocrine-Related Cancer. PMID 28487351 DOI: 10.1530/Erc-17-0006  0.381
2017 Leung Y, Govindarajah V, Cheong A, Song D, Zhu X, Ying J, Kendler A, Medvedovic M, Belcher S, Ho S. Abstract 4826: Maternal high butter fat intake heightens mammary cancer risk in offsprings gestationally exposed to bisphenol A at environmentally relevant dose Cancer Research. 77: 4826-4826. DOI: 10.1158/1538-7445.Am2017-4826  0.393
2016 Ho SM, Cheong A, Adgent MA, Veevers J, Suen AA, Tam NN, Leung YK, Jefferson WN, Williams CJ. Environmental Factors, Epigenetics, and Developmental Origin of Reproductive Disorders. Reproductive Toxicology (Elmsford, N.Y.). PMID 27421580 DOI: 10.1016/J.Reprotox.2016.07.011  0.353
2016 Cheong A, Zhang X, Cheung YY, Tang WY, Chen J, Ye SH, Medvedovic M, Leung YK, Prins GS, Ho SM. DNA methylome changes by estradiol benzoate and bisphenol A links early-life environmental exposures to prostate cancer risk. Epigenetics. 0. PMID 27415467 DOI: 10.1080/15592294.2016.1208891  0.303
2016 Govindarajah V, Leung YK, Ying J, Gear R, Bornschein RL, Medvedovic M, Ho SM. In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands. The Journal of Nutritional Biochemistry. 29: 73-82. PMID 26895667 DOI: 10.1016/J.Jnutbio.2015.11.003  0.373
2015 Stevenson M, Alexander B, Baxter CS, Leung YK. Evaluating Endocrine Disruption Activity of Deposits on Firefighting Gear Using a Sensitive and High Throughput Screening Method. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 57: e153-e157. PMID 26641839 DOI: 10.1097/Jom.0000000000000577  0.357
2015 Panchanathan R, Liu H, Leung YK, Ho SM, Choubey D. Bisphenol A (BPA) stimulates the interferon signaling and activates the inflammasome activity in myeloid cells. Molecular and Cellular Endocrinology. 415: 45-55. PMID 26277401 DOI: 10.1016/J.Mce.2015.08.003  0.304
2015 Schade GR, Holt SK, Zhang X, Wright JL, Zhao SS, Kolb S, Lam H, Levin L, Leung Y, Ho S, Stanford J. PD47-03 EXPRESSION OF CYTOPLASMIC ERβ1 AND NUCLEAR ERβ2 IS ASSOCIATED WITH POOR OUTCOMES FOLLOWING RADICAL PROSTATECTOMY FOR LOCALIZED PROSTATE CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.2747  0.339
2014 Yang WS, Chadalapaka G, Cho SG, Lee SO, Jin UH, Jutooru I, Choi K, Leung YK, Ho SM, Safe S, Kim K. The transcriptional repressor ZBTB4 regulates EZH2 through a MicroRNA-ZBTB4-specificity protein signaling axis. Neoplasia (New York, N.Y.). 16: 1059-69. PMID 25499219 DOI: 10.1016/J.Neo.2014.09.011  0.329
2014 Leung YK, Chan QK, Ng CF, Ma FM, Tse HM, To KF, Maranchie J, Ho SM, Lau KM. Hsa-miRNA-765 as a key mediator for inhibiting growth, migration and invasion in fulvestrant-treated prostate cancer. Plos One. 9: e98037. PMID 24837491 DOI: 10.1371/Journal.Pone.0098037  0.328
2013 Lee MT, Ho SM, Tarapore P, Chung I, Leung YK. Estrogen receptor β isoform 5 confers sensitivity of breast cancer cell lines to chemotherapeutic agent-induced apoptosis through interaction with Bcl2L12. Neoplasia (New York, N.Y.). 15: 1262-71. PMID 24339738 DOI: 10.1593/Neo.131184  0.338
2013 Lee MT, Leung YK, Chung I, Tarapore P, Ho SM. Estrogen receptor β (ERβ1) transactivation is differentially modulated by the transcriptional coregulator Tip60 in a cis-acting element-dependent manner. The Journal of Biological Chemistry. 288: 25038-52. PMID 23857583 DOI: 10.1074/Jbc.M113.476952  0.331
2013 Lee MT, Ouyang B, Ho SM, Leung YK. Differential expression of estrogen receptor beta isoforms in prostate cancer through interplay between transcriptional and translational regulation. Molecular and Cellular Endocrinology. 376: 125-35. PMID 23806560 DOI: 10.1016/J.Mce.2013.06.023  0.375
2012 Leung YK, Lee MT, Lam HM, Tarapore P, Ho SM. Estrogen receptor-beta and breast cancer: translating biology into clinical practice. Steroids. 77: 727-37. PMID 22465878 DOI: 10.1016/J.Steroids.2012.03.008  0.35
2012 Lam HM, Suresh Babu CV, Wang J, Yuan Y, Lam YW, Ho SM, Leung YK. Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion. Molecular and Cellular Endocrinology. 358: 27-35. PMID 22370157 DOI: 10.1016/J.Mce.2012.02.012  0.329
2011 Ho SM, Lee MT, Lam HM, Leung YK. Estrogens and prostate cancer: etiology, mediators, prevention, and management. Endocrinology and Metabolism Clinics of North America. 40: 591-614, ix. PMID 21889723 DOI: 10.1016/J.Ecl.2011.05.002  0.366
2011 Leung YK, Ho SM. Estrogen receptor β: switching to a new partner and escaping from estrogen. Science Signaling. 4: pe19. PMID 21487104 DOI: 10.1126/Scisignal.2001991  0.4
2010 Zhang X, Wu M, Xiao H, Lee MT, Levin L, Leung YK, Ho SM. Methylation of a single intronic CpG mediates expression silencing of the PMP24 gene in prostate cancer. The Prostate. 70: 765-76. PMID 20054818 DOI: 10.1002/Pros.21109  0.371
2007 Hess-Wilson JK, Webb SL, Daly HK, Leung YK, Boldison J, Comstock CE, Sartor MA, Ho SM, Knudsen KE. Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status. Environmental Health Perspectives. 115: 1646-53. PMID 18007998 DOI: 10.1289/Ehp.10283  0.393
2006 Ho SM, Leung YK, Chung I. Estrogens and antiestrogens as etiological factors and therapeutics for prostate cancer. Annals of the New York Academy of Sciences. 1089: 177-93. PMID 17261766 DOI: 10.1196/Annals.1386.005  0.407
2006 Mak P, Leung YK, Tang WY, Harwood C, Ho SM. Apigenin suppresses cancer cell growth through ERbeta. Neoplasia (New York, N.Y.). 8: 896-904. PMID 17132221 DOI: 10.1593/neo.06538  0.314
2006 Leung YK, Gao Y, Lau KM, Zhang X, Ho SM. ICI 182,780-regulated gene expression in DU145 prostate cancer cells is mediated by estrogen receptor-beta/NFkappaB crosstalk. Neoplasia (New York, N.Y.). 8: 242-9. PMID 16756716 DOI: 10.1593/Neo.05853  0.379
2005 Leung YK, Lau KM, Mobley J, Jiang Z, Ho SM. Overexpression of cytochrome P450 1A1 and its novel spliced variant in ovarian cancer cells: alternative subcellular enzyme compartmentation may contribute to carcinogenesis. Cancer Research. 65: 3726-34. PMID 15867368 DOI: 10.1158/0008-5472.Can-04-3771  0.34
2004 Zhu X, Leav I, Leung YK, Wu M, Liu Q, Gao Y, McNeal JE, Ho SM. Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. The American Journal of Pathology. 164: 2003-12. PMID 15161636 DOI: 10.1016/S0002-9440(10)63760-1  0.388
2003 Tam NN, Gao Y, Leung YK, Ho SM. Androgenic regulation of oxidative stress in the rat prostate: involvement of NAD(P)H oxidases and antioxidant defense machinery during prostatic involution and regrowth. The American Journal of Pathology. 163: 2513-22. PMID 14633623 DOI: 10.1016/S0002-9440(10)63606-1  0.322
2003 Lau KM, Tam NN, Thompson C, Cheng RY, Leung YK, Ho SM. Age-associated changes in histology and gene-expression profile in the rat ventral prostate. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 743-57. PMID 12746483 DOI: 10.1097/01.Lab.0000069519.06988.24  0.334
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