Year |
Citation |
Score |
2023 |
Bornstein R, Mulholland MT, Sedensky M, Morgan P, Johnson SC. Glutamine metabolism in diseases associated with mitochondrial dysfunction. Molecular and Cellular Neurosciences. 126: 103887. PMID 37586651 DOI: 10.1016/j.mcn.2023.103887 |
0.328 |
|
2022 |
Hanaford A, Johnson SC. The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence. Orphanet Journal of Rare Diseases. 17: 335. PMID 36056365 DOI: 10.1186/s13023-022-02495-3 |
0.315 |
|
2022 |
Gonzalez B, Tare A, Ryu S, Johnson SC, Atzmon G, Barzilai N, Kaeberlein M, Suh Y. High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity. Geroscience. PMID 35948858 DOI: 10.1007/s11357-022-00634-z |
0.322 |
|
2021 |
Bornstein R, James K, Stokes J, Park KY, Kayser EB, Snell J, Bard A, Chen Y, Kalume F, Johnson SC. Differential effects of mTOR inhibition and dietary ketosis in a mouse model of subacute necrotizing encephalomyelopathy. Neurobiology of Disease. 105594. PMID 34933094 DOI: 10.1016/j.nbd.2021.105594 |
0.301 |
|
2020 |
Bornstein R, Gonzalez B, Johnson SC. Mitochondrial pathways in human health and aging. Mitochondrion. PMID 32738358 DOI: 10.1016/J.Mito.2020.07.007 |
0.49 |
|
2020 |
Johnson SC, Kayser EB, Bornstein R, Stokes J, Bitto A, Park KY, Pan A, Sun G, Raftery D, Kaeberlein M, Sedensky MM, Morgan PG. Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease. Molecular Genetics and Metabolism. PMID 32331968 DOI: 10.1016/J.Ymgme.2020.03.007 |
0.368 |
|
2019 |
Kahn-Kirby AH, Amagata A, Maeder CI, Mei JJ, Sideris S, Kosaka Y, Hinman A, Malone SA, Bruegger JJ, Wang L, Kim V, Shrader WD, Hoff KG, Latham JC, Ashley EA, ... ... Johnson SC, et al. Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy. Plos One. 14: e0214250. PMID 30921410 DOI: 10.1371/Journal.Pone.0214250 |
0.383 |
|
2018 |
Johnson SC. Nutrient Sensing, Signaling and Ageing: The Role of IGF-1 and mTOR in Ageing and Age-Related Disease. Sub-Cellular Biochemistry. 90: 49-97. PMID 30779006 DOI: 10.1007/978-981-13-2835-0_3 |
0.429 |
|
2018 |
Johnson SC, Pan A, Li L, Sedensky M, Morgan P. Neurotoxicity of anesthetics: Mechanisms and meaning from mouse intervention studies. Neurotoxicology and Teratology. PMID 30472095 DOI: 10.1016/J.Ntt.2018.11.004 |
0.327 |
|
2018 |
Johnson SC, Martinez F, Bitto A, Gonzalez B, Tazaerslan C, Cohen C, Delaval L, Timsit J, Knebelmann B, Terzi F, Mahal T, Zhu Y, Morgan PG, Sedensky MM, Kaeberlein M, et al. mTOR inhibitors may benefit kidney transplant recipients with mitochondrial diseases. Kidney International. PMID 30471880 DOI: 10.1016/J.Kint.2018.08.038 |
0.437 |
|
2018 |
Venot Q, Blanc T, Rabia SH, Berteloot L, Ladraa S, Duong JP, Blanc E, Johnson SC, Hoguin C, Boccara O, Sarnacki S, Boddaert N, Pannier S, Martinez F, Magassa S, et al. Targeted therapy in patients with PIK3CA-related overgrowth syndrome. Nature. PMID 29899452 DOI: 10.1038/S41586-018-0217-9 |
0.335 |
|
2016 |
Johnson SC, Gonzalez B, Zhang Q, Milholland B, Zhang Z, Suh Y. Network analysis of mitonuclear GWAS reveals functional networks and tissue expression profiles of disease-associated genes. Human Genetics. PMID 27704213 DOI: 10.1007/S00439-016-1736-9 |
0.351 |
|
2016 |
Johnson SC, Kaeberlein M. Rapamycin in aging and disease: maximizing efficacy while minimizing side effects. Oncotarget. PMID 27384492 DOI: 10.18632/Oncotarget.10381 |
0.368 |
|
2015 |
McCormick MA, Delaney JR, Tsuchiya M, Tsuchiyama S, Shemorry A, Sim S, Chou AC, Ahmed U, Carr D, Murakami CJ, Schleit J, Sutphin GL, Wasko BM, Bennett CF, Wang AM, ... ... Johnson SC, et al. A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metabolism. PMID 26456335 DOI: 10.1016/J.Cmet.2015.09.008 |
0.365 |
|
2015 |
Johnson SC, Yanos ME, Bitto A, Castanza A, Gagnidze A, Gonzalez B, Gupta K, Hui J, Jarvie C, Johnson BM, Letexier N, McCanta L, Sangesland M, Tamis O, Uhde L, et al. Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice. Frontiers in Genetics. 6: 247. PMID 26257774 DOI: 10.3389/Fgene.2015.00247 |
0.517 |
|
2015 |
Johnson SC, Dong X, Vijg J, Suh Y. Genetic evidence for common pathways in human age-related diseases. Aging Cell. PMID 26077337 DOI: 10.1111/Acel.12362 |
0.437 |
|
2015 |
Johnson SC, Sangesland M, Kaeberlein M, Rabinovitch PS. Modulating mTOR in aging and health. Interdisciplinary Topics in Gerontology. 40: 107-27. PMID 25341517 DOI: 10.1159/000364974 |
0.523 |
|
2014 |
Johnson SC. Translational Medicine. A target for pharmacological intervention in an untreatable human disease. Science (New York, N.Y.). 346: 1192. PMID 25477449 DOI: 10.1126/Science.Aaa1811 |
0.399 |
|
2013 |
Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, et al. mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome. Science (New York, N.Y.). 342: 1524-8. PMID 24231806 DOI: 10.1126/Science.1244360 |
0.58 |
|
2013 |
Johnson SC, Martin GM, Rabinovitch PS, Kaeberlein M. Preserving youth: does rapamycin deliver? Science Translational Medicine. 5: 211fs40. PMID 24225941 DOI: 10.1126/Scitranslmed.3007316 |
0.486 |
|
2013 |
Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Castanza A, Hsieh EJ, Moller RM, Wasko BM, Delaney JR, Sutphin GL, Carr D, Murakami CJ, Tocchi A, Xian B, et al. Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell. 12: 1050-61. PMID 23837470 DOI: 10.1111/Acel.12130 |
0.552 |
|
2013 |
Johnson SC, Rabinovitch PS, Kaeberlein M. mTOR is a key modulator of ageing and age-related disease. Nature. 493: 338-45. PMID 23325216 DOI: 10.1038/Nature11861 |
0.559 |
|
2013 |
Kayser E, Johnson SC, Kaeberlein MR, Sedensky MM, Morgan PG. Capacity for oxidative phosphorylation does not decline with age in mitochondria from ndufs4 knockout mice Mitochondrion. 13: 915. DOI: 10.1016/J.Mito.2013.07.045 |
0.377 |
|
2012 |
Johnson S, Rabinovitch P. Ex Vivo Imaging of Excised Tissue Using Vital Dyes and Confocal Microscopy Current Protocols in Immunology. 61. PMID 22752953 DOI: 10.1002/0471142956.Cy0939S61 |
0.423 |
|
2012 |
Dai DF, Chen T, Johnson SC, Szeto H, Rabinovitch PS. Cardiac aging: from molecular mechanisms to significance in human health and disease. Antioxidants & Redox Signaling. 16: 1492-526. PMID 22229339 DOI: 10.1089/Ars.2011.4179 |
0.658 |
|
2011 |
Dai DF, Johnson SC, Villarin JJ, Chin MT, Nieves-Cintrón M, Chen T, Marcinek DJ, Dorn GW, Kang YJ, Prolla TA, Santana LF, Rabinovitch PS. Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure. Circulation Research. 108: 837-46. PMID 21311045 DOI: 10.1161/Circresaha.110.232306 |
0.631 |
|
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