Michael X. Henderson - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Neurodegeneration, Chaperones

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lubben N, Brynildsen JK, Webb CM, Li HL, Leyns CEG, Changolkar L, Zhang B, Meymand ES, O'Reilly M, Madaj Z, DeWeerd D, Fell MJ, Lee VMY, Bassett DS, Henderson MX. LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression. Translational Neurodegeneration. 13: 13. PMID 38438877 DOI: 10.1186/s40035-024-00403-2  0.338
2023 Goralski T, Meyerdirk L, Breton L, Brasseur L, Kurgat K, DeWeerd D, Turner L, Becker K, Adams M, Newhouse D, Henderson MX. Spatial transcriptomics reveals molecular dysfunction associated with Lewy pathology. Biorxiv : the Preprint Server For Biology. PMID 37292685 DOI: 10.1101/2023.05.17.541144  0.392
2023 Leyns CEG, Prigent A, Beezhold B, Yao L, Hatcher NG, Tao P, Kang J, Suh E, Van Deerlin VM, Trojanowski JQ, Lee VMY, Kennedy ME, Fell MJ, Henderson MX. Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease. Npj Parkinson's Disease. 9: 74. PMID 37169750 DOI: 10.1038/s41531-023-00517-w  0.337
2022 Chen L, Nagaraja C, Daniels S, Fisk ZA, Dvorak R, Meyerdirk L, Steiner JA, Escobar Galvis ML, Henderson MX, Rousseaux MWC, Brundin P, Chu HY. Synaptic location is a determinant of the detrimental effects of α-Synuclein pathology to glutamatergic transmission in the basolateral amygdala. Elife. 11. PMID 35775627 DOI: 10.7554/eLife.78055  0.357
2022 Henderson MX, Henrich MT, Geibl FF, Oertel WH, Brundin P, Surmeier DJ. The roles of connectivity and neuronal phenotype in determining the pattern of α-synuclein pathology in Parkinson's disease. Neurobiology of Disease. 105687. PMID 35283326 DOI: 10.1016/j.nbd.2022.105687  0.378
2021 Henderson MX, Changolkar L, Trojanowski JQ, Lee VMY. LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons. Journal of Parkinson's Disease. PMID 33720852 DOI: 10.3233/JPD-212562  0.342
2019 Henderson MX, Sedor S, McGeary I, Cornblath EJ, Peng C, Riddle DM, Li HL, Zhang B, Brown HJ, Olufemi MF, Bassett DS, Trojanowski JQ, Lee VMY. Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult. Neuron. PMID 31899072 DOI: 10.1016/J.Neuron.2019.12.004  0.483
2019 Henderson MX, Covell DJ, Chung CH, Pitkin RM, Sandler RM, Decker SC, Riddle DM, Zhang B, Gathagan RJ, James MJ, Trojanowski JQ, Brunden KR, Lee VMY, Luk KC. Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease. Neurobiology of Disease. 104712. PMID 31837422 DOI: 10.1016/J.Nbd.2019.104712  0.428
2019 Henderson MX, Sengupta M, Trojanowski JQ, Lee VMY. Alzheimer's disease tau is a prominent pathology in LRRK2 Parkinson's disease. Acta Neuropathologica Communications. 7: 183. PMID 31733655 DOI: 10.1186/S40478-019-0836-X  0.372
2019 Henderson MX, Cornblath EJ, Darwich A, Zhang B, Brown H, Gathagan RJ, Sandler RM, Bassett DS, Trojanowski JQ, Lee VMY. Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis. Nature Neuroscience. 22: 1248-1257. PMID 31346295 DOI: 10.1038/S41593-019-0457-5  0.424
2019 Henderson MX, Trojanowski JQ, Lee VM. α-Synuclein Pathology in Parkinson's Disease and Related α-Synucleinopathies. Neuroscience Letters. 134316. PMID 31170426 DOI: 10.1016/J.Neulet.2019.134316  0.464
2019 Henderson MX, Sengupta M, McGeary I, Zhang B, Olufemi MF, Brown H, Trojanowski JQ, Lee VMY. LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic mice. Acta Neuropathologica Communications. 7: 28. PMID 30808409 DOI: 10.1186/S40478-019-0679-5  0.42
2018 Henderson MX, Peng C, Trojanowski JQ, Lee VMY. LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons. Acta Neuropathologica Communications. 6: 45. PMID 29855356 DOI: 10.1186/S40478-018-0550-0  0.484
2017 Henderson MX, Chung CH, Riddle DM, Zhang B, Gathagan RJ, Seeholzer SH, Trojanowski JQ, Lee VMY. Unbiased proteomics of early Lewy body formation model implicates active microtubule affinity-regulating kinases (MARKs) in synucleinopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28522732 DOI: 10.1523/Jneurosci.2705-16.2017  0.475
2015 Henderson MX, Wirak GS, Zhang YQ, Dai F, Ginsberg SD, Dolzhanskaya N, Staropoli JF, Nijssen PC, Lam TT, Roth AF, Davis NG, Dawson G, Velinov M, Chandra SS. Neuronal ceroid lipofuscinosis with DNAJC5/CSPα mutation has PPT1 pathology and exhibit aberrant protein palmitoylation. Acta Neuropathologica. PMID 26659577 DOI: 10.1007/S00401-015-1512-2  0.533
2013 Tucker K, Cho S, Thiebaud N, Henderson MX, Fadool DA. Glucose sensitivity of mouse olfactory bulb neurons is conveyed by a voltage-gated potassium channel. The Journal of Physiology. 591: 2541-61. PMID 23478133 DOI: 10.1113/Jphysiol.2013.254086  0.475
2012 Zhang YQ, Henderson MX, Colangelo CM, Ginsberg SD, Bruce C, Wu T, Chandra SS. Identification of CSPα clients reveals a role in dynamin 1 regulation. Neuron. 74: 136-50. PMID 22500636 DOI: 10.1016/J.Neuron.2012.01.029  0.49
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