Ssang-Taek Lim, Ph.D. - Publications

Affiliations: 
2003 University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Cell Biology

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Finney AC, Scott ML, Reeves KA, Wang D, Alfaidi M, Schwartz JC, Chitmon CM, Acosta CH, Murphy JM, Alexander JS, Pattillo CB, Lim ST, Orr AW. EphA2 signaling within integrin adhesions regulates fibrillar adhesion elongation and fibronectin deposition. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 34537369 DOI: 10.1016/j.matbio.2021.09.001  0.411
2020 Murphy JM, Rodriguez YAR, Jeong K, Ahn EE, Lim SS. Targeting focal adhesion kinase in cancer cells and the tumor microenvironment. Experimental & Molecular Medicine. PMID 32514188 DOI: 10.1038/s12276-020-0447-4  0.338
2020 Murphy JM, Jeong K, Lim SS. FAK Family Kinases in Vascular Diseases. International Journal of Molecular Sciences. 21. PMID 32455571 DOI: 10.3390/ijms21103630  0.313
2016 Lim S, Smith KR, Lim ST, Tian R, Lu J, Tan M. Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation. Cell & Bioscience. 6: 25. PMID 27087918 DOI: 10.1186/S13578-016-0089-3  0.422
2016 Kim JH, Baddoo MC, Park EY, Stone JK, Park H, Butler TW, Huang G, Yan X, Pauli-Behn F, Myers RM, Tan M, Flemington EK, Lim ST, Ahn EE. SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes. Molecular Cell. 61: 859-873. PMID 26990989 DOI: 10.1016/J.Molcel.2016.02.024  0.317
2015 Yoon H, Dehart JP, Murphy JM, Lim ST. Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 63: 114-28. PMID 25380750 DOI: 10.1369/0022155414561498  0.311
2013 Lim ST. Nuclear FAK: a new mode of gene regulation from cellular adhesions. Molecules and Cells. 36: 1-6. PMID 23686429 DOI: 10.1007/s10059-013-0139-1  0.415
2012 Jung O, Choi S, Jang SB, Lee SA, Lim ST, Choi YJ, Kim HJ, Kim DH, Kwak TK, Kim H, Kang M, Lee MS, Park SY, Ryu J, Jeong D, et al. Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells. Journal of Cell Science. 125: 5960-73. PMID 23077174 DOI: 10.1242/Jcs.100586  0.52
2012 Lim ST, Miller NL, Chen XL, Tancioni I, Walsh CT, Lawson C, Uryu S, Weis SM, Cheresh DA, Schlaepfer DD. Nuclear-localized focal adhesion kinase regulates inflammatory VCAM-1 expression. The Journal of Cell Biology. 197: 907-19. PMID 22734001 DOI: 10.1083/Jcb.201109067  0.459
2012 Miller NL, Lawson C, Chen XL, Lim ST, Schlaepfer DD. Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins. Plos One. 7: e37830. PMID 22649559 DOI: 10.1371/Journal.Pone.0037830  0.448
2012 Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1. Plos One. 7: e36753. PMID 22586492 DOI: 10.1371/Journal.Pone.0036753  0.328
2012 Lawson C, Lim ST, Uryu S, Chen XL, Calderwood DA, Schlaepfer DD. FAK promotes recruitment of talin to nascent adhesions to control cell motility. The Journal of Cell Biology. 196: 223-32. PMID 22270917 DOI: 10.1083/Jcb.201108078  0.498
2012 Chen XL, Nam JO, Jean C, Lawson C, Walsh CT, Goka E, Lim ST, Tomar A, Tancioni I, Uryu S, Guan JL, Acevedo LM, Weis SM, Cheresh DA, Schlaepfer DD. VEGF-induced vascular permeability is mediated by FAK. Developmental Cell. 22: 146-57. PMID 22264731 DOI: 10.1016/J.Devcel.2011.11.002  0.443
2012 Tancioni I, Lawson C, Miller NLG, Uryu S, Jean C, Chen XL, Lim S, Ward K, Schlaepfer DD. Abstract 1254: FAK activity regulates αvβ5 integrin and osteopontin expression to control breast and ovarian cancer anchorage-independent growth Cancer Research. 72: 1254-1254. DOI: 10.1158/1538-7445.Am2012-1254  0.438
2011 Yu HG, Nam JO, Miller NL, Tanjoni I, Walsh C, Shi L, Kim L, Chen XL, Tomar A, Lim ST, Schlaepfer DD. p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase. Cancer Research. 71: 360-70. PMID 21224360 DOI: 10.1158/0008-5472.Can-10-2894  0.506
2010 Lim ST, Chen XL, Tomar A, Miller NL, Yoo J, Schlaepfer DD. Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation. The Journal of Biological Chemistry. 285: 21526-36. PMID 20442405 DOI: 10.1074/Jbc.M110.129999  0.429
2010 Tanjoni I, Walsh C, Uryu S, Tomar A, Nam JO, Mielgo A, Lim ST, Liang C, Koenig M, Sun C, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments. Cancer Biology & Therapy. 9: 764-77. PMID 20234191 DOI: 10.4161/Cbt.9.10.11434  0.448
2010 Lim ST, Miller NL, Nam JO, Chen XL, Lim Y, Schlaepfer DD. Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival. The Journal of Biological Chemistry. 285: 1743-53. PMID 19880522 DOI: 10.1074/Jbc.M109.064212  0.449
2010 Tanjoni I, Walsh C, Nam J, Lim S, Schlaepfer DD. Abstract 1204: FAK inhibition selectively promotes tumor cell apoptosis in three-dimensional environments and suppresses tumor cell metastasis Cancer Research. 70: 1204-1204. DOI: 10.1158/1538-7445.Am10-1204  0.438
2009 Tomar A, Lim ST, Lim Y, Schlaepfer DD. A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells. Journal of Cell Science. 122: 1852-62. PMID 19435801 DOI: 10.1242/Jcs.046870  0.501
2008 Lim ST, Mikolon D, Stupack DG, Schlaepfer DD. FERM control of FAK function: implications for cancer therapy. Cell Cycle (Georgetown, Tex.). 7: 2306-14. PMID 18677107 DOI: 10.4161/Cc.6367  0.528
2008 Ossovskaya V, Lim ST, Ota N, Schlaepfer DD, Ilic D. FAK nuclear export signal sequences. Febs Letters. 582: 2402-6. PMID 18549812 DOI: 10.1016/J.Febslet.2008.06.004  0.457
2008 Weis SM, Lim ST, Lutu-Fuga KM, Barnes LA, Chen XL, Göthert JR, Shen TL, Guan JL, Schlaepfer DD, Cheresh DA. Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK. The Journal of Cell Biology. 181: 43-50. PMID 18391070 DOI: 10.1083/Jcb.200710038  0.426
2008 Lim ST, Chen XL, Lim Y, Hanson DA, Vo TT, Howerton K, Larocque N, Fisher SJ, Schlaepfer DD, Ilic D. Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. Molecular Cell. 29: 9-22. PMID 18206965 DOI: 10.1016/J.Molcel.2007.11.031  0.413
2008 Lim Y, Lim ST, Tomar A, Gardel M, Bernard-Trifilo JA, Chen XL, Uryu SA, Canete-Soler R, Zhai J, Lin H, Schlaepfer WW, Nalbant P, Bokoch G, Ilic D, Waterman-Storer C, et al. PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility. The Journal of Cell Biology. 180: 187-203. PMID 18195107 DOI: 10.1083/Jcb.200708194  0.541
2008 Wu L, Bernard-Trifilo JA, Lim Y, Lim ST, Mitra SK, Uryu S, Chen M, Pallen CJ, Cheung NK, Mikolon D, Mielgo A, Stupack DG, Schlaepfer DD. Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility. Oncogene. 27: 1439-48. PMID 17828307 DOI: 10.1038/Sj.Onc.1210770  0.519
2008 Tomar A, Lim S, Lim Y, Schlaepfer DD. Cell polarity regulated by a FAK-p120RasGAP-p190RhoGAP complex Matrix Biology. 27: 59. DOI: 10.1016/J.Matbio.2008.09.420  0.318
2008 Lim S, Chen XL, Tomar A, Miller NL, Schlaepfer DD. FAK activity is essential for vascular development Matrix Biology. 27: 46. DOI: 10.1016/J.Matbio.2008.09.366  0.313
2008 Lim S, Miller NL, Chen XL, Lim Y, Schlaepfer DD. Pyk2 FERM regulates p53 in the absence of FAK Matrix Biology. 27: 38. DOI: 10.1016/J.Matbio.2008.09.335  0.323
2007 Ilic D, Mao-Qiang M, Crumrine D, Dolganov G, Larocque N, Xu P, Demerjian M, Brown BE, Lim ST, Ossovskaya V, Schlaepfer DD, Fisher SJ, Feingold KR, Elias PM, Mauro TM. Focal adhesion kinase controls pH-dependent epidermal barrier homeostasis by regulating actin-directed Na+/H+ exchanger 1 plasma membrane localization. The American Journal of Pathology. 170: 2055-67. PMID 17525272 DOI: 10.2353/Ajpath.2007.061277  0.356
2007 Schlaepfer DD, Hou S, Lim ST, Tomar A, Yu H, Lim Y, Hanson DA, Uryu SA, Molina J, Mitra SK. Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression. The Journal of Biological Chemistry. 282: 17450-9. PMID 17438336 DOI: 10.1074/Jbc.M610672200  0.458
2006 Bernard-Trifilo JA, Lim ST, Hou S, Schlaepfer DD, Ilic D. Analyzing FAK and Pyk2 in early integrin signaling events. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 14.7. PMID 18228476 DOI: 10.1002/0471143030.Cb1407S30  0.523
2005 Hsia DA, Lim ST, Bernard-Trifilo JA, Mitra SK, Tanaka S, den Hertog J, Streblow DN, Ilic D, Ginsberg MH, Schlaepfer DD. Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src. Molecular and Cellular Biology. 25: 9700-12. PMID 16227616 DOI: 10.1128/Mcb.25.21.9700-9712.2005  0.443
2004 Ahn EY, Lim ST, Cook WJ, McDonald JM. Calmodulin binding to the Fas death domain. Regulation by Fas activation. The Journal of Biological Chemistry. 279: 5661-6. PMID 14594800 DOI: 10.1074/Jbc.M311040200  0.384
2003 Lim ST, Longley RL, Couchman JR, Woods A. Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase C alpha (PKC alpha) increases focal adhesion localization of PKC alpha. The Journal of Biological Chemistry. 278: 13795-802. PMID 12571249 DOI: 10.1074/Jbc.M208300200  0.58
2002 Couchman JR, Vogt S, Lim ST, Lim Y, Oh ES, Prestwich GD, Theibert A, Lee W, Woods A. Regulation of inositol phospholipid binding and signaling through syndecan-4. The Journal of Biological Chemistry. 277: 49296-303. PMID 12377772 DOI: 10.1074/Jbc.M209679200  0.608
1998 Oh ES, Woods A, Lim ST, Theibert AW, Couchman JR. Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4,5- bisphosphate coordinately regulate protein kinase C activity Journal of Biological Chemistry. 273: 10624-10629. PMID 9553124 DOI: 10.1074/Jbc.273.17.10624  0.624
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