Jibran Younis Khokhar, Ph.D. - Publications

2018- Biomedical Science University of Guelph, Guelph, Ontario, Canada 
Addictions/Mental Health

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ellner D, Hallam B, Frie JA, Thorpe HHA, Shoaib M, Kayir H, Jenkins BW, Khokhar JY. Discordant Effects of Cannabinoid 2 Receptor Antagonism/Inverse Agonism During Adolescence on Pavlovian and Instrumental Reward Learning in Adult Male Rats. Frontiers in Synaptic Neuroscience. 13: 732402. PMID 34526887 DOI: 10.3389/fnsyn.2021.732402  1
2021 Wallin DJ, Sullivan EDK, Bragg EM, Khokhar JY, Lu H, Doucette WT. Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat. Journal of Visualized Experiments : Jove. PMID 34515680 DOI: 10.3791/62596  1
2021 Inayat M, Cruz-Sanchez A, Thorpe HHA, Frie JA, Richards BA, Khokhar JY, Arruda-Carvalho M. Promoting and Optimizing the Use of 3D Printed Objects in Spontaneous Recognition Memory Tasks in Rodents: A Method for Improving Rigor and Reproducibility. Eneuro. PMID 34503967 DOI: 10.1523/ENEURO.0319-21.2021  1
2021 Buckhalter S, Soubeyrand E, Ferrone SAE, Rasmussen DJ, Manduca JD, Al-Abdul-Wahid MS, Frie JA, Khokhar JY, Akhtar TA, Perreault ML. The Antidepressant-Like and Analgesic Effects of Kratom Alkaloids are accompanied by Changes in Low Frequency Oscillations but not ΔFosB Accumulation. Frontiers in Pharmacology. 12: 696461. PMID 34413776 DOI: 10.3389/fphar.2021.696461  1
2021 McKie GL, Shamshoum H, Hunt KL, Thorpe HHA, Dibe HA, Khokhar JY, Doucette CA, Wright DC. Intermittent cold exposure improves glucose homeostasis despite exacerbating diet-induced obesity in mice housed at thermoneutrality. The Journal of Physiology. PMID 34192813 DOI: 10.1113/JP281774  1
2021 Thériault RK, St-Denis M, Hewitt T, Khokhar JY, Lalonde J, Perreault ML. Sex-Specific Cannabidiol- and Iloperidone-Induced Neuronal Activity Changes in an In Vitro MAM Model System of Schizophrenia. International Journal of Molecular Sciences. 22. PMID 34073710 DOI: 10.3390/ijms22115511  1
2021 Henricks AM, Sullivan ED, Khokhar JY. In Memoriam-Alan Ivan Green, MD (1943-2020). Journal of Dual Diagnosis. 1-2. PMID 33792512 DOI: 10.1080/15504263.2021.1904176  1
2021 Oleson EB, Khokhar JY. Cannabinoids: Emerging developments in neuropsychopharmacology and biological psychiatry. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110305. PMID 33737216 DOI: 10.1016/j.pnpbp.2021.110305  0.01
2021 Renda B, Andrade AK, Stone APS, El Azali R, Sharivker M, Khokhar JY, Antenos M, Murray JE. Adolescent nicotine and footshock exposure augments adult nicotine self-administration and drug-seeking without affecting baseline anxiety-like behaviour or stress responsivity in male rats. Psychopharmacology. PMID 33649967 DOI: 10.1007/s00213-021-05803-0  1
2021 Jenkins BW, Khokhar JY. Cannabis Use and Mental Illness: Understanding Circuit Dysfunction Through Preclinical Models. Frontiers in Psychiatry. 12: 597725. PMID 33613338 DOI: 10.3389/fpsyt.2021.597725  1
2020 Thorpe HHA, Talhat MA, Khokhar JY. High genes: Genetic underpinnings of cannabis use phenotypes. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110164. PMID 33152387 DOI: 10.1016/j.pnpbp.2020.110164  1
2020 Hamidullah S, Lutelmowski CD, Creighton SD, Luciani KR, Frie JA, Winters BD, Khokhar J. Effects of vapourized THC and voluntary alcohol drinking during adolescence on cognition, reward, and anxiety-like behaviours in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110141. PMID 33069816 DOI: 10.1016/j.pnpbp.2020.110141  1
2020 Mielnik CA, Sugamori KS, Finlay DB, Thorpe HHA, Schapira M, Sivananthan N, Li CK, Lam VM, Harrington S, Abdelrahman MH, Trembleau LA, McIntyre Burnham W, Khokhar JY, Salahpour A, Ramsey AJ, et al. A novel allosteric modulator of the cannabinoid CB receptor ameliorates hyperdopaminergia endophenotypes in rodent models. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33036015 DOI: 10.1038/s41386-020-00876-5  1
2020 Frie JA, Underhill J, Zhao B, de Guglielmo G, Tyndale RF, Khokhar JY. OpenVape: an Open-Source E-Cigarette Vapour Exposure Device for Rodents. Eneuro. PMID 32859723 DOI: 10.1523/ENEURO.0279-20.2020  1
2020 Hamidullah S, Thorpe HHA, Frie JA, Mccurdy RD, Khokhar JY. Adolescent Substance Use and the Brain: Behavioral, Cognitive and Neuroimaging Correlates. Frontiers in Human Neuroscience. 14: 298. PMID 32848673 DOI: 10.3389/Fnhum.2020.00298  1
2020 Renda B, Andrade AK, Frie JA, Sgarbossa CL, Murray JE, Khokhar JY. High-dose adolescent nicotine exposure permits spontaneous nicotine self-administration in adult male rats. Drug and Alcohol Dependence. 215: 108215. PMID 32781311 DOI: 10.1016/J.Drugalcdep.2020.108215  1
2020 Thériault RK, Manduca JD, Blight CR, Khokhar JY, Akhtar TA, Perreault ML. Acute mitragynine administration suppresses cortical oscillatory power and systems theta coherence in rats. Journal of Psychopharmacology (Oxford, England). 269881120914223. PMID 32248751 DOI: 10.1177/0269881120914223  1
2020 Luciani KR, Frie JA, Khokhar JY. An Open Source Automated Bar Test for Measuring Catalepsy in Rats. Eneuro. PMID 32198157 DOI: 10.1523/ENEURO.0488-19.2020  1
2019 Nelong TF, Jenkins BW, Perreault ML, Khokhar JY. EXTENDED ATTENUATION OF CORTICOSTRIATAL POWER AND COHERENCE AFTER ACUTE EXPOSURE TO VAPOURIZED Δ9 TETRAHYDROCANNABINOL IN RATS. The Canadian Journal of Addiction. 10: 60-66. PMID 32944610 DOI: 10.1097/cxa.0000000000000063  1
2019 Thorpe HHA, Hamidullah S, Jenkins BW, Khokhar JY. Adolescent Neurodevelopment and Substance Use: Receptor Expression and Behavioral Consequences. Pharmacology & Therapeutics. 107431. PMID 31706976 DOI: 10.1016/J.Pharmthera.2019.107431  1
2019 Frie JA, Khokhar JY. An Open Source Automated Two-Bottle Choice Test Apparatus for Rats. Hardwarex. 5. PMID 31245655 DOI: 10.1016/J.Ohx.2019.E00061  1
2019 Dwiel LL, Khokhar JY, Connerney MA, Green AI, Doucette WT. Finding the balance between model complexity and performance: Using ventral striatal oscillations to classify feeding behavior in rats. Plos Computational Biology. 15: e1006838. PMID 31009448 DOI: 10.1371/Journal.Pcbi.1006838  1
2018 Doucette WT, Dwiel L, Boyce JE, Simon AA, Khokhar JY, Green AI. Machine Learning Based Classification of Deep Brain Stimulation Outcomes in a Rat Model of Binge Eating Using Ventral Striatal Oscillations. Frontiers in Psychiatry. 9: 336. PMID 30123143 DOI: 10.3389/Fpsyt.2018.00336  1
2018 Khokhar JY, Henricks AM, Sullivan EDK, Green AI. Unique Effects of Clozapine: A Pharmacological Perspective. Advances in Pharmacology (San Diego, Calif.). 82: 137-162. PMID 29413518 DOI: 10.1016/Bs.Apha.2017.09.009  1
2017 Green AI, Khokhar JY. Addiction and schizophrenia: A translational perspective. Schizophrenia Research. PMID 29046253 DOI: 10.1016/J.Schres.2017.10.008  1
2017 Whitfield-Gabrieli S, Fischer AS, Henricks AM, Khokhar JY, Roth RM, Brunette MF, Green AI. Understanding marijuana's effects on functional connectivity of the default mode network in patients with schizophrenia and co-occurring cannabis use disorder: A pilot investigation. Schizophrenia Research. PMID 28823723 DOI: 10.1016/J.Schres.2017.07.029  1
2017 Khokhar JY, Dwiel LL, Henricks AM, Doucette WT, Green AI. The link between schizophrenia and substance use disorder: A unifying hypothesis. Schizophrenia Research. PMID 28416205 DOI: 10.1016/J.Schres.2017.04.016  1
2017 Khokhar JY, Todd TP. Behavioral predictors of alcohol drinking in a neurodevelopmental rat model of schizophrenia and co-occurring alcohol use disorder. Schizophrenia Research. PMID 28285734 DOI: 10.1016/J.Schres.2017.02.029  0.01
2016 Khokhar JY, Green AI. Effects of iloperidone, combined with desipramine, on alcohol drinking in the Syrian golden hamster. Neuropharmacology. 105: 25-34. PMID 26796639 DOI: 10.1016/J.Neuropharm.2016.01.017  1
2015 Doucette WT, Khokhar JY, Green AI. Nucleus accumbens deep brain stimulation in a rat model of binge eating. Translational Psychiatry. 5: e695. PMID 26670280 DOI: 10.1038/Tp.2015.197  1
2015 Chau DT, Khokhar JY, Gulick D, Dawson R, Green AI. Desipramine enhances the ability of paliperidone to decrease alcohol drinking. Journal of Psychiatric Research. 69: 9-18. PMID 26343589 DOI: 10.1016/J.Jpsychires.2015.07.010  1
2015 Khokhar JY, Chau DT, Dawson R, Green AI. Clozapine reconstructed: Haloperidol's ability to reduce alcohol intake in the Syrian golden hamster can be enhanced through noradrenergic modulation by desipramine and idazoxan. Drug and Alcohol Dependence. 152: 277-81. PMID 25979645 DOI: 10.1016/J.Drugalcdep.2015.04.003  1
2014 Gulick D, Chau DT, Khokhar JY, Dawson R, Green AI. Desipramine enhances the ability of risperidone to decrease alcohol intake in the Syrian golden hamster. Psychiatry Research. 218: 329-34. PMID 24836200 DOI: 10.1016/J.Psychres.2014.04.038  1
2014 Khokhar JY, Tyndale RF. Intracerebroventricularly and systemically delivered inhibitor of brain CYP2B (C8-Xanthate), even following chlorpyrifos exposure, reduces chlorpyrifos activation and toxicity in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 49-60. PMID 24798379 DOI: 10.1093/Toxsci/Kfu075  1
2013 Chau DT, Khokhar JY, Dawson R, Ahmed J, Xie H, Green AI. The comparative effects of clozapine versus haloperidol on initiation and maintenance of alcohol drinking in male alcohol-preferring P rat. Alcohol (Fayetteville, N.Y.). 47: 611-8. PMID 24280363 DOI: 10.1016/J.Alcohol.2013.10.002  1
2013 Zhou K, Khokhar JY, Zhao B, Tyndale RF. First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo. Biochemical Pharmacology. 85: 1848-55. PMID 23623752 DOI: 10.1016/J.Bcp.2013.04.014  1
2012 Khokhar JY, Tyndale RF. Rat brain CYP2B-enzymatic activation of chlorpyrifos to the oxon mediates cholinergic neurotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 325-35. PMID 22287024 DOI: 10.1093/Toxsci/Kfs029  1
2011 Khokhar JY, Tyndale RF. Drug metabolism within the brain changes drug response: selective manipulation of brain CYP2B alters propofol effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 692-700. PMID 21107310 DOI: 10.1038/Npp.2010.202  1
2010 Khokhar JY, Miksys SL, Tyndale RF. Rat brain CYP2B induction by nicotine is persistent and does not involve nicotinic acetylcholine receptors. Brain Research. 1348: 1-9. PMID 20599831 DOI: 10.1016/J.Brainres.2010.06.035  1
2010 Khokhar JY, Ferguson CS, Zhu AZ, Tyndale RF. Pharmacogenetics of drug dependence: role of gene variations in susceptibility and treatment. Annual Review of Pharmacology and Toxicology. 50: 39-61. PMID 20055697 DOI: 10.1146/Annurev.Pharmtox.010909.105826  1
2009 Yue J, Khokhar J, Miksys S, Tyndale RF. Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake. European Journal of Pharmacology. 609: 88-95. PMID 19285975 DOI: 10.1016/J.Ejphar.2009.03.015  1
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