Jibran Younis Khokhar, Ph.D. - Publications

2018- Biomedical Science University of Guelph, Guelph, Ontario, Canada 
Addictions/Mental Health

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 McCunn P, Chen X, Gimi B, Green AI, Khokhar JY. Glutamine and GABA alterations in cingulate cortex may underlie alcohol drinking in a rat model of co-occurring alcohol use disorder and schizophrenia: an 1H-MRS study. Schizophrenia (Heidelberg, Germany). 8: 67. PMID 35999232 DOI: 10.1038/s41537-022-00272-6  0.602
2022 Henricks AM, Sullivan EDK, Dwiel LL, Li JY, Wallin DJ, Khokhar JY, Doucette WT. Maternal immune activation and adolescent alcohol exposure increase alcohol drinking and disrupt cortical-striatal-hippocampal oscillations in adult offspring. Translational Psychiatry. 12: 288. PMID 35859084 DOI: 10.1038/s41398-022-02065-y  0.795
2022 Al-Sabagh Y, Thorpe HHA, Jenkins BW, Hamidullah S, Talhat MA, Suggett CB, Reitz CJ, Rasouli M, Martino TA, Khokhar JY. α Knockout Reduces Ethanol Consumption and Preference in Male and Female Mice. International Journal of Molecular Sciences. 23. PMID 35563586 DOI: 10.3390/ijms23095197  0.689
2022 Rizk AA, Jenkins BW, Al-Sabagh Y, Hamidullah S, Reitz CJ, Rasouli M, Martino TA, Khokhar JY. The Impact of Sex, Circadian Disruption, and the Clock Genotype on Alcohol Drinking in Mice. Genes. 13. PMID 35456507 DOI: 10.3390/genes13040701  0.683
2022 Kayir H, Jenkins BW, Alural B, Khokhar JY. Clozapine Increases Nestin Concentration in the Adult Male Rat Hippocampus: A Preliminary Study. International Journal of Molecular Sciences. 23. PMID 35408792 DOI: 10.3390/ijms23073436  0.691
2022 Doucette WT, Smedley EB, Ruiz-Jaquez M, Khokhar JY, Smith KS. Chronic chemogenetic manipulation of ventral pallidum targeted neurons in male rats fed an obesogenic diet. Brain Research. 1784: 147886. PMID 35314149 DOI: 10.1016/j.brainres.2022.147886  0.755
2022 Jenkins BW, Buckhalter S, Perreault ML, Khokhar JY. Cannabis Vapor Exposure Alters Neural Circuit Oscillatory Activity in a Neurodevelopmental Model of Schizophrenia: Exploring the Differential Impact of Cannabis Constituents. Schizophrenia Bulletin Open. 3: sgab052. PMID 35036917 DOI: 10.1093/schizbullopen/sgab052  0.721
2021 Ruffolo J, Frie JA, Thorpe HHA, Talhat MA, Khokhar JY. Alcohol and Vaporized Nicotine Co-Exposure During Adolescence Contribute Differentially to Sex-Specific Behavioral Effects in Adulthood. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 34865152 DOI: 10.1093/ntr/ntab250  0.303
2021 Sullivan EDK, Locke LN, Wallin DJ, Khokhar JY, Bragg EM, Henricks AM, Doucette WT. The Impact of Adolescent Alcohol Exposure on Nicotine Behavioral Sensitization in the Adult Male Neonatal Ventral Hippocampal Lesion Rat. Frontiers in Behavioral Neuroscience. 15: 760791. PMID 34858148 DOI: 10.3389/fnbeh.2021.760791  0.785
2021 Ellner D, Hallam B, Frie JA, Thorpe HHA, Shoaib M, Kayir H, Jenkins BW, Khokhar JY. Discordant Effects of Cannabinoid 2 Receptor Antagonism/Inverse Agonism During Adolescence on Pavlovian and Instrumental Reward Learning in Adult Male Rats. Frontiers in Synaptic Neuroscience. 13: 732402. PMID 34526887 DOI: 10.3389/fnsyn.2021.732402  0.7
2021 Wallin DJ, Sullivan EDK, Bragg EM, Khokhar JY, Lu H, Doucette WT. Acquisition of Resting-State Functional Magnetic Resonance Imaging Data in the Rat. Journal of Visualized Experiments : Jove. PMID 34515680 DOI: 10.3791/62596  0.749
2021 Jenkins BW, Khokhar JY. Cannabis Use and Mental Illness: Understanding Circuit Dysfunction Through Preclinical Models. Frontiers in Psychiatry. 12: 597725. PMID 33613338 DOI: 10.3389/fpsyt.2021.597725  0.685
2020 Hamidullah S, Lutelmowski CD, Creighton SD, Luciani KR, Frie JA, Winters BD, Khokhar J. Effects of vapourized THC and voluntary alcohol drinking during adolescence on cognition, reward, and anxiety-like behaviours in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110141. PMID 33069816 DOI: 10.1016/j.pnpbp.2020.110141  0.333
2020 Frie JA, Underhill J, Zhao B, de Guglielmo G, Tyndale RF, Khokhar JY. OpenVape: an Open-Source E-Cigarette Vapour Exposure Device for Rodents. Eneuro. PMID 32859723 DOI: 10.1523/ENEURO.0279-20.2020  0.45
2020 Hamidullah S, Thorpe HHA, Frie JA, Mccurdy RD, Khokhar JY. Adolescent Substance Use and the Brain: Behavioral, Cognitive and Neuroimaging Correlates. Frontiers in Human Neuroscience. 14: 298. PMID 32848673 DOI: 10.3389/Fnhum.2020.00298  0.346
2020 Renda B, Andrade AK, Frie JA, Sgarbossa CL, Murray JE, Khokhar JY. High-dose adolescent nicotine exposure permits spontaneous nicotine self-administration in adult male rats. Drug and Alcohol Dependence. 215: 108215. PMID 32781311 DOI: 10.1016/J.Drugalcdep.2020.108215  0.302
2019 Nelong TF, Jenkins BW, Perreault ML, Khokhar JY. EXTENDED ATTENUATION OF CORTICOSTRIATAL POWER AND COHERENCE AFTER ACUTE EXPOSURE TO VAPOURIZED Δ9 TETRAHYDROCANNABINOL IN RATS. The Canadian Journal of Addiction. 10: 60-66. PMID 32944610 DOI: 10.1097/cxa.0000000000000063  0.7
2019 Thorpe HHA, Hamidullah S, Jenkins BW, Khokhar JY. Adolescent Neurodevelopment and Substance Use: Receptor Expression and Behavioral Consequences. Pharmacology & Therapeutics. 107431. PMID 31706976 DOI: 10.1016/J.Pharmthera.2019.107431  0.726
2019 Frie JA, Khokhar JY. An Open Source Automated Two-Bottle Choice Test Apparatus for Rats. Hardwarex. 5. PMID 31245655 DOI: 10.1016/J.Ohx.2019.E00061  0.366
2019 Dwiel LL, Khokhar JY, Connerney MA, Green AI, Doucette WT. Finding the balance between model complexity and performance: Using ventral striatal oscillations to classify feeding behavior in rats. Plos Computational Biology. 15: e1006838. PMID 31009448 DOI: 10.1371/Journal.Pcbi.1006838  0.743
2019 Nelong TF, Jenkins BW, Perreault ML, Khokhar JY. Extended Attenuation of Corticostriatal Power and Coherence after Acute Exposure to Vapourized Δ9-Tetrahydrocannabinol in Rats The Canadian Journal of Addiction. 10: 60-66. DOI: 10.1097/cxa.0000000000000063  0.677
2019 Green A, Khokhar J. 36. SCHIZOPHRENIA AND SUBSTANCE USE DISORDER: A UNIFYING HYPOTHESIS Schizophrenia Bulletin. 45: S147-S147. DOI: 10.1093/Schbul/Sbz022.147  0.57
2018 Doucette WT, Dwiel L, Boyce JE, Simon AA, Khokhar JY, Green AI. Machine Learning Based Classification of Deep Brain Stimulation Outcomes in a Rat Model of Binge Eating Using Ventral Striatal Oscillations. Frontiers in Psychiatry. 9: 336. PMID 30123143 DOI: 10.3389/Fpsyt.2018.00336  0.752
2018 Khokhar JY, Henricks AM, Sullivan EDK, Green AI. Unique Effects of Clozapine: A Pharmacological Perspective. Advances in Pharmacology (San Diego, Calif.). 82: 137-162. PMID 29413518 DOI: 10.1016/Bs.Apha.2017.09.009  0.589
2017 Green AI, Khokhar JY. Addiction and schizophrenia: A translational perspective. Schizophrenia Research. PMID 29046253 DOI: 10.1016/J.Schres.2017.10.008  0.544
2017 Whitfield-Gabrieli S, Fischer AS, Henricks AM, Khokhar JY, Roth RM, Brunette MF, Green AI. Understanding marijuana's effects on functional connectivity of the default mode network in patients with schizophrenia and co-occurring cannabis use disorder: A pilot investigation. Schizophrenia Research. PMID 28823723 DOI: 10.1016/J.Schres.2017.07.029  0.739
2017 Khokhar JY, Dwiel LL, Henricks AM, Doucette WT, Green AI. The link between schizophrenia and substance use disorder: A unifying hypothesis. Schizophrenia Research. PMID 28416205 DOI: 10.1016/J.Schres.2017.04.016  0.755
2017 Khokhar JY, Todd TP. Behavioral predictors of alcohol drinking in a neurodevelopmental rat model of schizophrenia and co-occurring alcohol use disorder. Schizophrenia Research. PMID 28285734 DOI: 10.1016/J.Schres.2017.02.029  0.484
2016 Khokhar JY, Green AI. Effects of iloperidone, combined with desipramine, on alcohol drinking in the Syrian golden hamster. Neuropharmacology. 105: 25-34. PMID 26796639 DOI: 10.1016/J.Neuropharm.2016.01.017  0.615
2015 Doucette WT, Khokhar JY, Green AI. Nucleus accumbens deep brain stimulation in a rat model of binge eating. Translational Psychiatry. 5: e695. PMID 26670280 DOI: 10.1038/Tp.2015.197  0.757
2015 Chau DT, Khokhar JY, Gulick D, Dawson R, Green AI. Desipramine enhances the ability of paliperidone to decrease alcohol drinking. Journal of Psychiatric Research. 69: 9-18. PMID 26343589 DOI: 10.1016/J.Jpsychires.2015.07.010  0.733
2015 Khokhar JY, Chau DT, Dawson R, Green AI. Clozapine reconstructed: Haloperidol's ability to reduce alcohol intake in the Syrian golden hamster can be enhanced through noradrenergic modulation by desipramine and idazoxan. Drug and Alcohol Dependence. 152: 277-81. PMID 25979645 DOI: 10.1016/J.Drugalcdep.2015.04.003  0.617
2015 Green AI, Khokhar JY. Deconstructing clozapine further: Toward medication for alcohol use disorder in schizophrenia Drug and Alcohol Dependence. 146: e128. DOI: 10.1016/J.Drugalcdep.2014.09.267  0.594
2014 Gulick D, Chau DT, Khokhar JY, Dawson R, Green AI. Desipramine enhances the ability of risperidone to decrease alcohol intake in the Syrian golden hamster. Psychiatry Research. 218: 329-34. PMID 24836200 DOI: 10.1016/J.Psychres.2014.04.038  0.721
2014 Khokhar JY, Tyndale RF. Intracerebroventricularly and systemically delivered inhibitor of brain CYP2B (C8-Xanthate), even following chlorpyrifos exposure, reduces chlorpyrifos activation and toxicity in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 140: 49-60. PMID 24798379 DOI: 10.1093/Toxsci/Kfu075  0.497
2013 Chau DT, Khokhar JY, Dawson R, Ahmed J, Xie H, Green AI. The comparative effects of clozapine versus haloperidol on initiation and maintenance of alcohol drinking in male alcohol-preferring P rat. Alcohol (Fayetteville, N.Y.). 47: 611-8. PMID 24280363 DOI: 10.1016/J.Alcohol.2013.10.002  0.614
2013 Zhou K, Khokhar JY, Zhao B, Tyndale RF. First demonstration that brain CYP2D-mediated opiate metabolic activation alters analgesia in vivo. Biochemical Pharmacology. 85: 1848-55. PMID 23623752 DOI: 10.1016/J.Bcp.2013.04.014  0.501
2012 Khokhar JY, Tyndale RF. Rat brain CYP2B-enzymatic activation of chlorpyrifos to the oxon mediates cholinergic neurotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 126: 325-35. PMID 22287024 DOI: 10.1093/Toxsci/Kfs029  0.534
2011 Khokhar JY, Tyndale RF. Drug metabolism within the brain changes drug response: selective manipulation of brain CYP2B alters propofol effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 692-700. PMID 21107310 DOI: 10.1038/Npp.2010.202  0.486
2010 Khokhar JY, Miksys SL, Tyndale RF. Rat brain CYP2B induction by nicotine is persistent and does not involve nicotinic acetylcholine receptors. Brain Research. 1348: 1-9. PMID 20599831 DOI: 10.1016/J.Brainres.2010.06.035  0.518
2010 Khokhar JY, Ferguson CS, Zhu AZ, Tyndale RF. Pharmacogenetics of drug dependence: role of gene variations in susceptibility and treatment. Annual Review of Pharmacology and Toxicology. 50: 39-61. PMID 20055697 DOI: 10.1146/Annurev.Pharmtox.010909.105826  0.627
2009 Yue J, Khokhar J, Miksys S, Tyndale RF. Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake. European Journal of Pharmacology. 609: 88-95. PMID 19285975 DOI: 10.1016/J.Ejphar.2009.03.015  0.503
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