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Ben G. Wen, Ph.D. - Publications

Affiliations: 
2002 University of California, San Diego, La Jolla, CA 
Area:
Immunology, Cell Biology, Molecular Biology
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Velcicky J, Mathison CJN, Nikulin V, Pflieger D, Epple R, Azimioara M, Cow C, Michellys PY, Rigollier P, Beisner DR, Bodendorf U, Guerini D, Liu B, Wen B, Zaharevitz S, et al. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. Acs Medicinal Chemistry Letters. 10: 887-892. PMID 31223443 DOI: 10.1021/acsmedchemlett.9b00044  0.669
2018 Velcicky J, Bodendorf U, Rigollier P, Epple R, Beisner DR, Guerini D, Smith P, Liu B, Feifel R, Wipfli P, Aichholz R, Couttet P, Dix I, Widmer T, Wen B, et al. Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo. Journal of Medicinal Chemistry. PMID 29359565 DOI: 10.1021/Acs.Jmedchem.7B01371  0.662
2015 Miller AT, Dahlberg C, Sandberg ML, Wen BG, Beisner DR, Hoerter JA, Parker A, Schmedt C, Stinson M, Avis J, Cienfuegos C, McPate M, Tranter P, Gosling M, Groot-Kormelink PJ, et al. Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease. Plos One. 10: e0131071. PMID 26121493 DOI: 10.1371/journal.pone.0131071  0.666
2011 Hannedouche S, Zhang J, Yi T, Shen W, Nguyen D, Pereira JP, Guerini D, Baumgarten BU, Roggo S, Wen B, Knochenmuss R, Noël S, Gessier F, Kelly LM, Vanek M, et al. Oxysterols direct immune cell migration via EBI2. Nature. 475: 524-7. PMID 21796212 DOI: 10.1038/Nature10280  0.365
2008 McGargill MA, Choy C, Wen BG, Hedrick SM. Drak2 regulates the survival of activated T cells and is required for organ-specific autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 7593-605. PMID 19017948 DOI: 10.4049/Jimmunol.181.11.7593  0.664
2005 Friedrich ML, Wen BG, Bain G, Kee BL, Katayama C, Murre C, Hedrick SM, Walsh CM. DRAK2, a lymphoid-enriched DAP kinase, regulates the TCR activation threshold during thymocyte selection. International Immunology. 17: 1379-90. PMID 16172133 DOI: 10.1093/Intimm/Dxh315  0.624
2004 McGargill MA, Wen BG, Walsh CM, Hedrick SM. A deficiency in Drak2 results in a T cell hypersensitivity and an unexpected resistance to autoimmunity. Immunity. 21: 781-91. PMID 15589167 DOI: 10.1016/J.Immuni.2004.10.008  0.689
2004 Wen BG, Pletcher MT, Warashina M, Choe SH, Ziaee N, Wiltshire T, Sauer K, Cooke MP. Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity. Proceedings of the National Academy of Sciences of the United States of America. 101: 5604-9. PMID 15064401 DOI: 10.1073/Pnas.0306907101  0.461
1998 Walsh CM, Wen BG, Chinnaiyan AM, O'Rourke K, Dixit VM, Hedrick SM. A role for FADD in T cell activation and development Immunity. 8: 439-449. PMID 9586634 DOI: 10.1016/S1074-7613(00)80549-X  0.678
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