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Barbara Ramsay Shaw - Publications

Affiliations: 
Chemistry Duke University, Durham, NC 
Area:
Boronated Nucleic Acids
Website:
http://www.chem.duke.edu/~brs/labgroup/shaw.html

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Xu Z, Shaw BR. Synthesis, Hydrolysis, and Protonation-Promoted Intramolecular Reductive Breakdown of Potential NRTIs: Stavudine α-P-Borano-γ-P-N-l-tryptophanyltriphosphates. Molecules (Basel, Switzerland). 20: 18808-18826. PMID 26556316 DOI: 10.3390/Molecules201018808  0.383
2014 Xu Z, Shaw BR. Phosphorus deprotonation by a non-nucleophilic base is critical for the synthesis of nucleoside α-P-boranodiphosphates via a phosphoramidite approach Tetrahedron Letters. 55: 5605-5608. DOI: 10.1016/J.Tetlet.2014.08.047  0.363
2013 Cheek MA, Sharaf ML, Dobrikov MI, Shaw BR. Inhibition of hepatitis C viral RNA-dependent RNA polymerase by α-P-boranophosphate nucleotides: exploring a potential strategy for mechanism-based HCV drug design. Antiviral Research. 98: 144-52. PMID 23466667 DOI: 10.1016/J.Antiviral.2013.02.014  0.745
2013 Xu Z, Sergueeva ZA, Shaw BR. Synthesis and hydrolytic properties of thymidine boranomonophosphate Tetrahedron Letters. 54: 2882-2885. DOI: 10.1016/J.Tetlet.2013.03.110  0.338
2012 Ray P, Cheek MA, Sharaf ML, Li N, Ellington AD, Sullenger BA, Shaw BR, White RR. Aptamer-mediated delivery of chemotherapy to pancreatic cancer cells. Nucleic Acid Therapeutics. 22: 295-305. PMID 23030589 DOI: 10.1089/Nat.2012.0353  0.73
2011 Johnson CN, Spring AM, Sergueev D, Shaw BR, Germann MW. Structural basis of the RNase H1 activity on stereo regular borano phosphonate DNA/RNA hybrids. Biochemistry. 50: 3903-12. PMID 21443203 DOI: 10.1021/Bi200083D  0.388
2008 Shaw BR, Moussa L, Sharaf M, Cheek M, Dobrikov M. Boranophosphate siRNA-aptamer chimeras for tumor-specific downregulation of cancer receptors and modulators. Nucleic Acids Symposium Series (2004). 655-6. PMID 18776550 DOI: 10.1093/nass/nrn331  0.687
2008 Cheek MA, Dobrikov MI, Wennefors CK, Xu Z, Hashmi SN, Shen X, Shaw BR. Synthesis and properties of (alpha-P-borano)-nucleoside 5'-triphosphate analogues as potential antiviral agents. Nucleic Acids Symposium Series (2004). 81-2. PMID 18776263 DOI: 10.1093/nass/nrn041  0.759
2008 Wennefors CK, Dobrikov MI, Xu Z, Li P, Shaw BR. Stereospecificity, substrate, and inhibitory properties of nucleoside diphosphate analogs for creatine and pyruvate kinases. Bioorganic Chemistry. 36: 169-77. PMID 18433830 DOI: 10.1016/J.Bioorg.2008.03.001  0.758
2007 Khan SI, Shaw BR. Efficient synthesis of thymidine boranophosphoramidates conjugated with amino acids. Nucleosides, Nucleotides & Nucleic Acids. 26: 621-3. PMID 18066867 DOI: 10.1080/15257770701490415  0.319
2007 Liu H, Hashmi SN, Shaw BR. Synthesis of 9-fluorenemethyl boranophosphonodiphosphate via an H-phosphonate approach. Nucleosides, Nucleotides & Nucleic Acids. 26: 1455-7. PMID 18066805 DOI: 10.1080/15257770701542413  0.442
2006 Hall AH, Wan J, Spesock A, Sergueeva Z, Shaw BR, Alexander KA. High potency silencing by single-stranded boranophosphate siRNA. Nucleic Acids Research. 34: 2773-81. PMID 16717282 DOI: 10.1093/Nar/Gkl339  0.498
2005 Li P, Xu Z, Liu H, Wennefors CK, Dobrikov MI, Ludwig J, Shaw BR. Synthesis of alpha-P-modified nucleoside diphosphates with ethylenediamine. Journal of the American Chemical Society. 127: 16782-3. PMID 16316213 DOI: 10.1021/Ja055179Y  0.766
2005 Khan SI, Dobrikov MI, Shaw BR. Synthesis of 5-ethynyl-2'-deoxyuridine-5'-boranomono phosphate as a potential thymidylate synthase inhibitor. Nucleosides, Nucleotides & Nucleic Acids. 24: 1047-9. PMID 16248089 DOI: 10.1081/Ncn-200060046  0.33
2005 Dobrikov MI, Shaw BR. Affinity of (alpha-P-borano)-NTP analogs to rabbit muscle pyruvate kinase. Nucleosides, Nucleotides & Nucleic Acids. 24: 983-7. PMID 16248077 DOI: 10.1081/Ncn-200059378  0.351
2005 Wang JX, Sergueev DS, Shaw BR. The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex. Nucleosides, Nucleotides & Nucleic Acids. 24: 951-5. PMID 16248070 DOI: 10.1081/Ncn-200059310  0.527
2005 Wang JX, Shaw BR. Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase. Nucleosides, Nucleotides & Nucleic Acids. 24: 947-50. PMID 16248069 DOI: 10.1081/Ncn-200059307  0.609
2005 Wan J, Shaw BR. Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase. Nucleosides, Nucleotides & Nucleic Acids. 24: 943-6. PMID 16248068 DOI: 10.1081/Ncn-200059303  0.508
2005 Li P, Shaw BR. Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose. Nucleosides, Nucleotides & Nucleic Acids. 24: 675-8. PMID 16248012 DOI: 10.1081/Ncn-200060244  0.308
2005 Li P, Shaw BR. Synthesis of nucleoside boranophosphoramidate prodrugs conjugated with amino acids. The Journal of Organic Chemistry. 70: 2171-83. PMID 15760202 DOI: 10.1021/Jo0481248  0.312
2004 Hall AHS, Wan J, Shaughnessy EE, Shaw BR, Alexander KA. RNA interference using boranophosphate siRNAs: Structure-activity relationships Nucleic Acids Research. 32: 5991-6000. PMID 15545637 DOI: 10.1093/Nar/Gkh936  0.507
2004 Li P, Shaw BR. Convenient synthesis of nucleoside borane diphosphate analogues: deoxy- and ribonucleoside 5'-P(alpha)-boranodiphosphates. The Journal of Organic Chemistry. 69: 7051-7. PMID 15471452 DOI: 10.1021/jo049094b  0.311
2003 Shaw BR, Dobrikov M, Wang X, Wan J, He K, Lin JL, Li P, Rait V, Sergueeva ZA, Sergueev D. Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA. Annals of the New York Academy of Sciences. 1002: 12-29. PMID 14751819 DOI: 10.1196/Annals.1281.004  0.762
2003 Dobrikov MI, Sergueeva ZA, Shaw BR. Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase. Nucleosides, Nucleotides & Nucleic Acids. 22: 1651-5. PMID 14565487 DOI: 10.1002/CHIN.200409205  0.386
2003 Wang X, Dobrikov M, Sergueev D, Shaw BR. RNase H activation by stereoregular boranophosphate oligonucleotide. Nucleosides, Nucleotides & Nucleic Acids. 22: 1151-3. PMID 14565367 DOI: 10.1081/Ncn-120022823  0.344
2003 Li P, Shaw BR. One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate. Nucleosides, Nucleotides & Nucleic Acids. 22: 699-701. PMID 14565257 DOI: 10.1081/Ncn-120022613  0.358
2003 Li P, Dobrikov M, Liu H, Shaw BR. Synthesis of acyclothymidine triphosphate and alpha-P-boranotriphosphate and their substrate properties with retroviral reverse transcriptase. Organic Letters. 5: 2401-3. PMID 12841740 DOI: 10.1021/Ol034538W  0.53
2003 Dobrikov MI, Grady KM, Shaw BR. Introduction of the alpha-P-borano-group into deoxynucleoside triphosphates increases their selectivity to HIV-1 reverse transcriptase relative to DNA polymerases. Nucleosides, Nucleotides & Nucleic Acids. 22: 275-82. PMID 12816386 DOI: 10.1081/Ncn-120021427  0.357
2002 Li P, Shaw BR. Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide. Chemical Communications (Cambridge, England). 2890-1. PMID 12478798 DOI: 10.1039/B207350A  0.357
2002 Li P, Shaw BR. Synthesis of prodrug candidates: conjugates of amino acid with nucleoside boranophosphate. Organic Letters. 4: 2009-12. PMID 12049504 DOI: 10.1021/Ol025832B  0.372
2002 Fisher AA, Ye D, Sergueev DS, Fisher MH, Shaw BR, Juliano RL. Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis. The Journal of Biological Chemistry. 277: 22980-4. PMID 11948195 DOI: 10.1074/Jbc.M203347200  0.341
2002 Lato SM, Ozerova ND, He K, Sergueeva Z, Shaw BR, Burke DH. Boron-containing aptamers to ATP. Nucleic Acids Research. 30: 1401-7. PMID 11884639 DOI: 10.1093/Nar/30.6.1401  0.631
2002 Shaw BR, Wan J, Wang X, Dobrikov M, He K, Porter K, Lin J, Rait V, Sergueev D, Sergueeva ZA. Reading and writing genetic information with boranophosphate (borane phosphate) mimics of nucleotides, DNA, and RNA Collection of Czechoslovak Chemical Communications. 5: 169-180. DOI: 10.1135/Css200205169  0.723
2001 Sergueev DS, Sergueeva ZA, Shaw BR. Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection. Nucleosides, Nucleotides & Nucleic Acids. 20: 789-95. PMID 11563117 DOI: 10.1081/Ncn-100002431  0.312
2001 Lin J, Shaw BR. Synthesis of new classes of boron-containing nucleotides. Nucleosides, Nucleotides & Nucleic Acids. 20: 587-96. PMID 11563076 DOI: 10.1081/Ncn-100002335  0.633
2001 Lin J, Shaw BR. Synthesis of a novel nucleic acid mimic: P-boranomethylphosphonate. Nucleosides, Nucleotides & Nucleic Acids. 20: 1325-8. PMID 11563014 DOI: 10.1081/Ncn-100002547  0.64
2001 Lin J, Porter KW, Shaw BR. Synthesis and properties of novel triphosphate analogues: ribonucleoside and deoxyribonucleoside (alpha-P-borano, alpha-P-thio)triphosphates. Nucleosides, Nucleotides & Nucleic Acids. 20: 1019-23. PMID 11562950 DOI: 10.1081/Ncn-100002482  0.638
2001 Summers JS, Shaw BR. Boranophosphates as mimics of natural phosphodiesters in DNA. Current Medicinal Chemistry. 8: 1147-55. PMID 11472233 DOI: 10.2174/0929867013372409  0.338
2001 He K, Shaw BR. Synthesis and separation of diastereomers of uridine 2',3'-cyclic boranophosphate. Bioorganic & Medicinal Chemistry Letters. 11: 615-7. PMID 11266154 DOI: 10.1016/S0960-894X(00)00700-9  0.565
2001 Lin J, He K, Shaw BR. Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate. Organic Letters. 3: 795-7. PMID 11263884 DOI: 10.1021/Ol0003230  0.705
2001 Lin J, He K, Shaw BR. Novel 3′,5′-cyclic nucleotide analogue: Adenosine 3′,5′-cyclic boranomonophosphate Organic Letters. 3: 795-797. DOI: 10.1021/ol0003230  0.496
2000 Astriab-Fisher A, Sergueev DS, Fisher M, Shaw BR, Juliano RL. Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochemical Pharmacology. 60: 83-90. PMID 10807948 DOI: 10.1016/S0006-2952(00)00310-5  0.336
2000 Shaw BR, Sergueev D, He K, Porter K, Summers J, Sergueeva Z, Rait V. Boranophosphate backbone: a mimic of phosphodiesters, phosphorothioates, and methyl phosphonates. Methods in Enzymology. 313: 226-57. PMID 10595359 DOI: 10.1016/S0076-6879(00)13015-0  0.583
2000 Lin J, Shaw BR. Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate Chemical Communications. 2115-2116. DOI: 10.1039/B005059H  0.605
2000 Lin J, Shaw BR. Synthesis of a boron analogue of glucose-conjugated nucleoside diphosphate: Nucleoside α-P-boranodiphosphoglucose Tetrahedron Letters. 41: 6701-6704. DOI: 10.1016/S0040-4039(00)01141-2  0.631
2000 Lin J, He K, Shaw BR. Synthesis of boron-containing ADP and GDP analogues: Nucleoside 5'-(Pα- boranodiphosphates) Helvetica Chimica Acta. 83: 1392-1397. DOI: 10.1002/1522-2675(20000705)83:7<1392::Aid-Hlca1392>3.0.Co;2-H  0.709
2000 Sergueeva ZA, Sergueev DS, Ribeiro AA, Summers JS, Shaw BR. Individual isomers of dinucleoside boranophosphates as synthons for incorporation into oligonucleotides: Synthesis and configurational assignment Helvetica Chimica Acta. 83: 1377-1391. DOI: 10.1002/1522-2675(20000705)83:7<1377::Aid-Hlca1377>3.0.Co;2-S  0.329
1999 Rait V, Sergueev D, Summers J, He K, Huang F, Krzyzanowska B, Shaw BR. Boranophosphate nucleic acids--a versatile DNA backbone. Nucleosides & Nucleotides. 18: 1379-80. PMID 10474223 DOI: 10.1080/07328319908044721  0.585
1999 Rait VK, Shaw BR. Boranophosphates support the RNase H cleavage of polyribonucleotides. Antisense & Nucleic Acid Drug Development. 9: 53-60. PMID 10192289 DOI: 10.1089/Oli.1.1999.9.53  0.342
1999 He K, Porter KW, Hasan A, Briley and JD, Shaw BR. Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease. Nucleic Acids Research. 27: 1788-94. PMID 10101185 DOI: 10.1093/Nar/27.8.1788  0.599
1999 Lin J, Shaw BR. Synthesis and properties of a novel phosphodiester analogue, nucleoside boranophosphorothioate Chemical Communications. 1517-1518. DOI: 10.1039/A901157I  0.611
1999 He K, Sergueev DS, Sergueeva ZA, Shaw BR. Synthesis of diuridine 3',5'-boranophosphate: H-phosphonate approach Tetrahedron Letters. 40: 4601-4604. DOI: 10.1016/S0040-4039(99)00742-X  0.573
1998 He K, Hasan A, Krzyzanowska B, Shaw BR. Synthesis and Separation of Diastereomers of Ribonucleoside 5'-(alpha-P-Borano)triphosphates. The Journal of Organic Chemistry. 63: 5769-5773. PMID 11672174 DOI: 10.1021/Jo972002G  0.617
1998 Sergueev DS, Shaw BR. H-phosphonate approach for solid-phase synthesis of oligodeoxyribonucleoside boranophosphates and their characterization Journal of the American Chemical Society. 120: 9417-9427. DOI: 10.1021/Ja9814927  0.322
1998 Krzyzanowska BK, He K, Hasan A, Shaw BR. A convenient synthesis of 2'-deoxyribonucleoside 5'-(α-P- borano)triphosphates Tetrahedron. 54: 5119-5128. DOI: 10.1016/S0040-4020(98)00251-8  0.6
1998 He K, Hasan A, Krzyzanowska B, Shaw BR. Synthesis and Separation of Diastereomers of Ribonucleoside 5′-(α-P-Borano)triphosphates Journal of Organic Chemistry. 63: 5769-5773.  0.523
1997 Sergueev D, Hasan A, Ramaswamy M, Shaw BR. Boranophosphate oligonucleotides: New synthetic approaches Nucleosides and Nucleotides. 16: 1533-1538. DOI: 10.1080/07328319708006223  0.335
1996 Hasan A, Li H, Tomasz J, Shaw BR. Base-boronated dinucleotides: synthesis and effect of N7-cyanoborane substitution on the base protons. Nucleic Acids Research. 24: 2150-7. PMID 8668548 DOI: 10.1093/Nar/24.11.2150  0.346
1996 Li H, Hardin C, Shaw BR. Hydrolysis of thymidine boranomonophosphate and stepwise deuterium substitution of the borane hydrogens. 31P and 11B NMR studies Journal of the American Chemical Society. 118: 6606-6614. DOI: 10.1021/Ja9540280  0.347
1996 Gao Q, Sood A, Shaw BR, Williams LD. 2′-Deoxycytidine-N3-cyanoborane Acta Crystallographica Section C: Crystal Structure Communications. 52: 1823-1825.  0.428
1995 Porter KW, Tomasz J, Huang F, Sood A, Shaw BR. N7-cyanoborane-2'-deoxyguanosine 5'-triphosphate is a good substrate for DNA polymerase. Biochemistry. 34: 11963-9. PMID 7547933 DOI: 10.1021/Bi00037A038  0.322
1995 Li H, Porter K, Huang F, Shaw BR. Boron-containing oligodeoxyribonucleotide 14mer duplexes: enzymatic synthesis and melting studies. Nucleic Acids Research. 23: 4495-501. PMID 7501475 DOI: 10.1093/Nar/23.21.4495  0.326
1992 MacPhail RA, Williams LD, Jones DA, Shaw BR. Variable temperature infrared spectroscopy of cytosine-guanine base pairs: tautomerism versus polarization. Journal of Biomolecular Structure & Dynamics. 9: 881-98. PMID 1524704 DOI: 10.1080/07391102.1992.10507964  0.526
1992 Tomasz J, Shaw BR, Porter K, Spielvogel BF, Sood A. 5′-P-borane-substituted thymidine monophosphate and triphosphate Angewandte Chemie (International Edition in English). 31: 1373-1375. DOI: 10.1002/Anie.199213731  0.365
1991 Spielvogel BF, Sood A, Shaw BR, Hall IH. From boron analogues of amino acids to boronated dna: Potential new pharmaceuticals and neutron capture agents Pure and Applied Chemistry. 63: 415-418. DOI: 10.1351/Pac199163030415  0.343
1990 Williams LD, Williams NG, Shaw BR. In a model cytosine:guanine base pair, one amino group rotates and the other does not Journal of the American Chemical Society. 112: 829-833. DOI: 10.1021/Ja00158A050  0.501
1990 Williams LD, Williams NG, Shaw BR. In a model C:G base pair, one amino group rotates and the other does not Journal of the American Chemical Society. 112: 829-833.  0.442
1989 Williams NG, Williams LD, Shaw BR. Dimers, trimers, and tetramers of cytosine with guanine Journal of the American Chemical Society. 111: 7205-7209. DOI: 10.1021/Ja00200A046  0.495
1987 Williams LD, Chawla B, Shaw BR. The hydrogen bonding of cytosine with guanine: calorimetric and 1H-nmr analysis of the molecular interactions of nucleic acid bases. Biopolymers. 26: 591-603. PMID 3567328 DOI: 10.1002/Bip.360260411  0.511
1987 Williams LD, Shaw BR. Protonated base pairs explain the ambiguous pairing properties of O6-methylguanine. Proceedings of the National Academy of Sciences of the United States of America. 84: 1779-83. PMID 3470757 DOI: 10.1073/Pnas.84.7.1779  0.528
1975 Shaw BR, Schurr JM. The association reaction of collagen model polypeptides (Pro‐Pro‐Gly)n Biopolymers. 14: 1951-1985. DOI: 10.1002/Bip.1975.360140913  0.517
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