Joseph M. Castellano - Related publications

2017- Neuroscience Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Aging, Neurodegeneration, Alzheimer's disease
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Taylor EN, Huang N, Wisco J, Wang Y, Morgan KG, Hamilton JA. The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds. Journal of Translational Medicine. 18: 277. PMID 32641073 DOI: 10.1186/s12967-020-02441-6   
2020 Hunsberger HC, Greenwood BP, Tolstikov V, Narain NR, Kiebish MA, Denny CA. Divergence in the metabolome between natural aging and Alzheimer's disease. Scientific Reports. 10: 12171. PMID 32699218 DOI: 10.1038/s41598-020-68739-z   
2020 Teissier T, Boulanger E, Deramecourt V. Normal ageing of the brain: Histological and biological aspects. Revue Neurologique. PMID 32418702 DOI: 10.1016/j.neurol.2020.03.017   
2020 Currais A, Huang L, Petrascheck M, Maher P, Schubert D. A chemical biology approach to identifying molecular pathways associated with aging. Geroscience. PMID 32705410 DOI: 10.1007/s11357-020-00238-5   
2020 Zhao Y, Qian R, Zhang J, Liu F, Iqbal K, Dai CL, Gong CX. Young blood plasma reduces Alzheimer's disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice. Alzheimer's Research & Therapy. 12: 70. PMID 32513253 DOI: 10.1186/s13195-020-00639-w   
2020 Vemula PK, Jing Y, Cicolini J, Zhang H, Mockett BG, Abraham WC, Liu P. Altered brain arginine metabolism with age in the APP/PSEN1 mouse model of Alzheimer's disease. Neurochemistry International. 104798. PMID 32711019 DOI: 10.1016/j.neuint.2020.104798   
2020 Volicer L. Physiological and pathological functions of beta-amyloid in the brain and alzheimer's disease: A review. The Chinese Journal of Physiology. 63: 95-100. PMID 32594062 DOI: 10.4103/CJP.CJP_10_20   
2020 Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... , et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/j.celrep.2020.107908   
2020 Liu M, Qian T, Zhou W, Tao X, Sang S, Zhao L. Beneficial effects of low-dose lithium on cognitive ability and pathological alteration of Alzheimer's disease transgenic mice model. Neuroreport. PMID 32639272 DOI: 10.1097/WNR.0000000000001499   
2020 Jang JW, Kim Y, Kim S, Park SW, Kwon SO, Park YH, Lim JS, Youn YC, Hun Kim S, Kim S, . Dynamic association between AT(N) profile and cognition mediated by cortical thickness in Alzheimer's continuum. Neuroimage. Clinical. 27: 102282. PMID 32590333 DOI: 10.1016/j.nicl.2020.102282   
2020 Chen Y, Fang L, Chen S, Zhou H, Fan Y, Lin L, Li J, Xu J, Chen Y, Ma Y, Chen Y. Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer's Disease. Biomed Research International. 2020: 8456596. PMID 32596386 DOI: 10.1155/2020/8456596   
2020 Nakanishi H, Nonaka S, Wu Z. Microglial cathepsin B and Porphyromonas gingivalis gingipains as potential therapeutic targets for sporadic Alzheimer's disease. Cns & Neurological Disorders Drug Targets. PMID 32640970 DOI: 10.2174/1871527319666200708125130   
2020 Fernandes A, Tábuas-Pereira M, Duro D, Lima M, Gens H, Santiago B, Durães J, Almeida MR, Leitão MJ, Baldeiras I, Santana I. C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia. Experimental Gerontology. 138: 111004. PMID 32561398 DOI: 10.1016/j.exger.2020.111004   
2020 Li W, Lo EH. Leaky memories: Impact of on blood-brain barrier and dementia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20938146. PMID 32600092 DOI: 10.1177/0271678X20938146   
2020 Golub JS, Sharma RK, Rippon BQ, Brickman AM, Luchsinger JA. The Association Between Early Age-Related Hearing Loss and Brain β-Amyloid. The Laryngoscope. PMID 32644260 DOI: 10.1002/lary.28859   
2020 Delabar JM, Ortner M, Simon S, Wijkhuisen A, Feraudet-Tarisse C, Pegon J, Vidal E, Hirschberg Y, Dubois B, Potier MC. Altered age-linked regulation of plasma DYRK1A in elderly cognitive complainers (INSIGHT-preAD study) with high brain amyloid load. Alzheimer's & Dementia (New York, N. Y.). 6: e12046. PMID 32642550 DOI: 10.1002/trc2.12046   
2020 Sun HL, Chen SH, Yu ZY, Cheng Y, Tian DY, Fan DY, He CY, Wang J, Sun PY, Chen Y, Tan CR, Wang JP, Song W, Zhou HD, Chen XW, et al. Blood cell-produced amyloid-β induces cerebral Alzheimer-type pathologies and behavioral deficits. Molecular Psychiatry. PMID 32681097 DOI: 10.1038/s41380-020-0842-1   
2020 Beyer MMS, Lonnemann N, Remus A, Latz E, Heneka MT, Korte M. Enduring changes in neuronal function upon systemic inflammation are NLRP3 inflammasome dependent. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32499379 DOI: 10.1523/JNEUROSCI.0200-20.2020   
2020 Zhou M, Haque RU, Dammer EB, Duong DM, Ping L, Johnson ECB, Lah JJ, Levey AI, Seyfried NT. Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical Proteomics. 17: 19. PMID 32514259 DOI: 10.1186/s12014-020-09285-8   
2020 Mamun AA, Uddin MS, Bin Bashar MF, Zaman S, Begum Y, Bulbul IJ, Islam MS, Sarwar MS, Mathew B, Amran MS, Md Ashraf G, Bin-Jumah MN, Mousa SA, Abdel-Daim MM. Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2020: 5086250. PMID 32509144 DOI: 10.1155/2020/5086250   
2020 Kim JW, Byun MS, Yi D, Lee JH, Jeon SY, Ko K, Jung G, Lee HN, Lee JY, Sohn CH, Lee YS, Shin SA, Kim YK, Lee DY, . Serum Uric Acid, Alzheimer-Related Brain Changes, and Cognitive Impairment. Frontiers in Aging Neuroscience. 12: 160. PMID 32581770 DOI: 10.3389/fnagi.2020.00160   
2020 Falangola MF, Nie X, Ward R, McKinnon ET, Dhiman S, Nietert PJ, Helpern JA, Jensen JH. Diffusion MRI detects early brain microstructure abnormalities in 2-month-old 3×Tg-AD mice. Nmr in Biomedicine. e4346. PMID 32557874 DOI: 10.1002/nbm.4346   
2020 Sharma VK, Singh TG, Singh S. Cyclic Nucleotides Signaling and Phosphodiesterase Inhibition: Defying Alzheimer's Disease. Current Drug Targets. PMID 32718286 DOI: 10.2174/1389450121666200727104728   
2020 Uddin MS, Kabir MT, Al Mamun A, Behl T, Mansouri RA, Aloqbi AA, Perveen A, Hafeez A, Ashraf GM. Exploring Potential of Alkaloidal Phytochemicals Targeting Neuroinflammatory Signaling of Alzheimer's Disease. Current Pharmaceutical Design. PMID 32473620 DOI: 10.2174/1381612826666200531151004   
2020 Ennerfelt HE, Lukens JR. The role of innate immunity in Alzheimer's disease. Immunological Reviews. PMID 32588460 DOI: 10.1111/imr.12896   
2020 Fiford CM, Nicholas JM, Biessels GJ, Lane CA, Cardoso MJ, Barnes J. High blood pressure predicts hippocampal atrophy rate in cognitively impaired elders. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12035. PMID 32587882 DOI: 10.1002/dad2.12035   
2020 Duan R, Xue X, Zhang QQ, Wang SY, Gong PY, E Y, Jiang T, Zhang YD. ACE2 activator diminazene aceturate ameliorates Alzheimer's disease-like neuropathology and rescues cognitive impairment in SAMP8 mice. Aging. 12. PMID 32701063 DOI: 10.18632/aging.103544   
2020 Ghosh A, Mizuno K, Tiwari SS, Proitsi P, Gomez Perez-Nievas B, Glennon E, Martinez-Nunez RT, Giese KP. Alzheimer's disease-related dysregulation of mRNA translation causes key pathological features with ageing. Translational Psychiatry. 10: 192. PMID 32546772 DOI: 10.1038/s41398-020-00882-7   
2020 Ren P, Ma M, Xie G, Wu Z, Wu D, . Altered complexity of resting-state BOLD activity in Alzheimer's disease-related neurodegeneration: a multiscale entropy analysis. Aging. 12. PMID 32649309 DOI: 10.18632/aging.103463   
2020 Mayagoitia K, Shin SD, Rubini M, Siebold L, Wilson CG, Bellinger DL, Figueroa JD, Soriano S. Short-term exposure to dietary cholesterol is associated with downregulation of interleukin-15, reduced thigmotaxis and memory impairment in mice. Behavioural Brain Research. 112779. PMID 32585301 DOI: 10.1016/j.bbr.2020.112779   
2020 Ortiz-Guerrero G, Gonzalez-Reyes RE, de-la-Torre A, Medina-Rincón G, Nava-Mesa MO. Pathophysiological Mechanisms of Cognitive Impairment and Neurodegeneration by Infection. Brain Sciences. 10. PMID 32545619 DOI: 10.3390/brainsci10060369   
2020 Levin OS, Bogolepova AN. [Cognitive rehabilitation of patients with neurodegenerative diseases]. Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova. 120: 110-115. PMID 32621476 DOI: 10.17116/jnevro2020120051110   
2020 Wang J, Sun BL, Xiang Y, Tian DY, Zhu C, Li WW, Liu YH, Bu XL, Shen LL, Jin WS, Wang Z, Zeng GH, Xu W, Chen LY, Chen XW, et al. Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer's disease-type pathology and cognitive deficits in APP/PS1 mice. Translational Psychiatry. 10: 230. PMID 32661266 DOI: 10.1038/s41398-020-00918-y   
2020 Kim JW, Byun MS, Lee JH, Yi D, Jeon SY, Sohn BK, Lee JY, Shin SA, Kim YK, Kang KM, Sohn CH, Lee DY, . Serum albumin and beta-amyloid deposition in the human brain. Neurology. PMID 32690787 DOI: 10.1212/WNL.0000000000010005   
2020 Kim JW, Byun MS, Lee JH, Yi D, Jeon SY, Sohn BK, Lee JY, Shin SA, Kim YK, Kang KM, Sohn CH, Lee DY, . Serum albumin and beta-amyloid deposition in the human brain. Neurology. PMID 32690787 DOI: 10.1212/WNL.0000000000010005   
2020 Gericke C, Mallone A, Engelhardt B, Nitsch RM, Ferretti MT. Oligomeric Forms of Human Amyloid-Beta(1-42) Inhibit Antigen Presentation. Frontiers in Immunology. 11: 1029. PMID 32582162 DOI: 10.3389/fimmu.2020.01029   
2020 Vasanthakumar A, Davis JW, Idler K, Waring JF, Asque E, Riley-Gillis B, Grosskurth S, Srivastava G, Kim S, Nho K, Nudelman KNH, Faber K, Sun Y, Foroud TM, Estrada K, ... , et al. Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease. Clinical Epigenetics. 12: 84. PMID 32539856 DOI: 10.1186/s13148-020-00864-y   
2020 Griswold AJ, Sivasankaran SK, Van Booven D, Gardner OK, Rajabli F, Whitehead PL, Hamilton-Nelson KL, Adams LD, Scott AM, Hofmann NK, Vance JM, Cuccaro ML, Bush WS, Martin ER, Byrd GS, et al. Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort. Journal of Alzheimer's Disease : Jad. PMID 32597797 DOI: 10.3233/JAD-190855   
2020 Braschi C, Capsoni S, Narducci R, Poli A, Sansevero G, Brandi R, Maffei L, Cattaneo A, Berardi N. Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis. Aging Clinical and Experimental Research. PMID 32676979 DOI: 10.1007/s40520-020-01646-5   
2020 Fernández-Mendívil C, Arreola MA, Hohsfield LA, Green KN, Lopez MG. Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression. Antioxidants (Basel, Switzerland). 9. PMID 32708329 DOI: 10.3390/antiox9070644   
2020 Fernández-Mendívil C, Arreola MA, Hohsfield LA, Green KN, Lopez MG. Aging and Progression of Beta-Amyloid Pathology in Alzheimer's Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression. Antioxidants (Basel, Switzerland). 9. PMID 32708329 DOI: 10.3390/antiox9070644   
2020 Choi DW, Kim TS, Kim YS, Kim DJ. Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia. Bmc Neurology. 20: 293. PMID 32758167 DOI: 10.1186/s12883-020-01859-1   
2020 Johnson LA. APOE and metabolic dysfunction in Alzheimer's disease. International Review of Neurobiology. 154: 131-151. PMID 32739002 DOI: 10.1016/bs.irn.2020.02.002   
2020 Haeger A, Mangin JF, Vignaud A, Poupon C, Grigis A, Boumezbeur F, Frouin V, Deverre JR, Sarazin M, Hertz-Pannier L, Bottlaender M, . Imaging the aging brain: study design and baseline findings of the SENIOR cohort. Alzheimer's Research & Therapy. 12: 77. PMID 32591008 DOI: 10.1186/s13195-020-00642-1   
2020 Son Y, Jeong YJ, Shin NR, Oh SJ, Nam KR, Choi HD, Choi JY, Lee HJ. Inhibition of Colony-Stimulating Factor 1 Receptor by PLX3397 Prevents Amyloid Beta Pathology and Rescues Dopaminergic Signaling in Aging 5xFAD Mice. International Journal of Molecular Sciences. 21. PMID 32756440 DOI: 10.3390/ijms21155553   
2020 Abe K, Chiba Y, Hattori S, Yoshimi A, Asami T, Katsuse O, Suda A, Hishimoto A, . Influence of plasma matrix metalloproteinase levels on longitudinal changes in Alzheimer's disease (AD) biomarkers and cognitive function in patients with mild cognitive impairment due to AD registered in the Alzheimer's Disease Neuroimaging Initiative database. Journal of the Neurological Sciences. 416: 116989. PMID 32603972 DOI: 10.1016/j.jns.2020.116989   
2020 Cheng X, Song C, Du Y, Gaur U, Yang M. Pharmacological Treatment of Alzheimer's Disease: Insights from . International Journal of Molecular Sciences. 21. PMID 32610577 DOI: 10.3390/ijms21134621   
2020 Gutiérrez-de Pablo V, Gómez C, Poza J, Maturana-Candelas A, Martins S, Gomes I, Lopes AM, Pinto N, Hornero R. Relationship between the Presence of the 4 Allele and EEG Complexity along the Alzheimer's Disease Continuum. Sensors (Basel, Switzerland). 20. PMID 32664228 DOI: 10.3390/s20143849   
2020 McKiernan EF, Mak E, Dounavi ME, Wells K, Ritchie C, Williams G, Su L, O'Brien J. Regional hyperperfusion in cognitively normal allele carriers in mid-life: analysis of ASL pilot data from the PREVENT-Dementia cohort. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 32586852 DOI: 10.1136/jnnp-2020-322924   
2020 Saez-Atienzar S, Masliah E. Cellular senescence and Alzheimer disease: the egg and the chicken scenario. Nature Reviews. Neuroscience. PMID 32601397 DOI: 10.1038/s41583-020-0325-z