☰

Lefteris C. Zacharia, Ph.D. - Publications

Affiliations: 
2002 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Pharmacology, Animal Physiology Biology
Tree Info Grants Similar researchers PubMed Report error

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Choukèr A, Ohta A, Martignoni A, Lukashev D, Zacharia LC, Jackson EK, Schnermann J, Ward JM, Kaufmann I, Klaunberg B, Sitkovsky MV, Thiel M. In vivo hypoxic preconditioning protects from warm liver ischemia-reperfusion injury through the adenosine A2B receptor. Transplantation. 94: 894-902. PMID 23073466 DOI: 10.1097/Tp.0B013E31826A9A46  0.444
2010 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Imthurn B, Rosselli M. Resveratrol, a red wine constituent, blocks the antimitogenic effects of estradiol on human female coronary artery smooth muscle cells. The Journal of Clinical Endocrinology and Metabolism. 95: E9-17. PMID 20534756 DOI: 10.1210/Jc.2010-0460  0.595
2008 Su Y, Huang X, Raskovalova T, Zacharia L, Lokshin A, Jackson E, Gorelik E. Cooperation of adenosine and prostaglandin E2 (PGE2) in amplification of cAMP-PKA signaling and immunosuppression. Cancer Immunology, Immunotherapy : Cii. 57: 1611-23. PMID 18327580 DOI: 10.1007/S00262-008-0494-5  0.499
2008 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Wunder D, Imthurn B, Rosselli M. Medroxyprogesterone abrogates the inhibitory effects of estradiol on vascular smooth muscle cells by preventing estradiol metabolism. Hypertension. 51: 1197-202. PMID 18259021 DOI: 10.1161/Hypertensionaha.107.106575  0.6
2008 Jackson EK, Gillespie DG, Zhu C, Ren J, Zacharia LC, Mi Z. Alpha2-adrenoceptors enhance angiotensin II-induced renal vasoconstriction: role for NADPH oxidase and RhoA. Hypertension. 51: 719-26. PMID 18250367 DOI: 10.1161/Hypertensionaha.107.096297  0.51
2007 Funakoshi H, Zacharia LC, Tang Z, Zhang J, Lee LL, Good JC, Herrmann DE, Higuchi Y, Koch WJ, Jackson EK, Chan TO, Feldman AM. A1 adenosine receptor upregulation accompanies decreasing myocardial adenosine levels in mice with left ventricular dysfunction. Circulation. 115: 2307-15. PMID 17438146 DOI: 10.1161/Circulationaha.107.694596  0.518
2007 Jackson EK, Mi Z, Zacharia LC, Tofovic SP, Dubey RK. The pancreatohepatorenal cAMP-adenosine mechanism. The Journal of Pharmacology and Experimental Therapeutics. 321: 799-809. PMID 17314200 DOI: 10.1124/Jpet.106.119164  0.543
2007 Jackson EK, Ren J, Zacharia LC, Mi Z. Characterization of renal ecto-phosphodiesterase. The Journal of Pharmacology and Experimental Therapeutics. 321: 810-5. PMID 17308037 DOI: 10.1124/Jpet.106.119057  0.523
2006 Zacharia LC, Jackson EK, Kloosterboer HJ, Imthurn B, Dubey RK. Conversion of tibolone to 7alpha-methyl-ethinyl estradiol using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry: interpretation and clinical implications. Menopause (New York, N.Y.). 13: 926-34. PMID 17006378 DOI: 10.1097/01.Gme.0000227331.49081.D7  0.481
2006 Arendash GW, Schleif W, Rezai-Zadeh K, Jackson EK, Zacharia LC, Cracchiolo JR, Shippy D, Tan J. Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production. Neuroscience. 142: 941-52. PMID 16938404 DOI: 10.1016/J.Neuroscience.2006.07.021  0.468
2006 Lokshin A, Raskovalova T, Huang X, Zacharia LC, Jackson EK, Gorelik E. Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells. Cancer Research. 66: 7758-65. PMID 16885379 DOI: 10.1158/0008-5472.Can-06-0478  0.545
2006 Yu W, Zacharia LC, Jackson EK, Apodaca G. Adenosine receptor expression and function in bladder uroepithelium. American Journal of Physiology. Cell Physiology. 291: C254-65. PMID 16571869 DOI: 10.1152/Ajpcell.00025.2006  0.526
2006 Jackson EK, Zacharia LC, Zhang M, Gillespie DG, Zhu C, Dubey RK. cAMP-adenosine pathway in the proximal tubule. The Journal of Pharmacology and Experimental Therapeutics. 317: 1219-29. PMID 16527902 DOI: 10.1124/Jpet.106.101360  0.569
2005 Raskovalova T, Huang X, Sitkovsky M, Zacharia LC, Jackson EK, Gorelik E. Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 4383-91. PMID 16177079 DOI: 10.4049/Jimmunol.175.7.4383  0.578
2005 Kochanek PM, Hendrich KS, Jackson EK, Wisniewski SR, Melick JA, Shore PM, Janesko KL, Zacharia L, Ho C. Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 1596-612. PMID 15931163 DOI: 10.1038/Sj.Jcbfm.9600154  0.496
2005 Dubey RK, Jackson EK, Gillespie DG, Rosselli M, Barchiesi F, Krust A, Keller H, Zacharia LC, Imthurn B. Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast. The Journal of Clinical Endocrinology and Metabolism. 90: 247-55. PMID 15507517 DOI: 10.1210/Jc.2003-032154  0.578
2004 Dubey RK, Imthurn B, Zacharia LC, Jackson EK. Hormone replacement therapy and cardiovascular disease: what went wrong and where do we go from here? Hypertension. 44: 789-95. PMID 15477384 DOI: 10.1161/01.Hyp.0000145988.95551.28  0.46
2004 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Imthurn B. Catecholamines block the antimitogenic effect of estradiol on human coronary artery smooth muscle cells. The Journal of Clinical Endocrinology and Metabolism. 89: 3922-31. PMID 15292328 DOI: 10.1210/Jc.2004-0115  0.617
2004 Zacharia LC, Dubey RK, Jackson EK. A gas chromatography/mass spectrometry assay to measure estradiol, catecholestradiols, and methoxyestradiols in plasma. Steroids. 69: 255-61. PMID 15183691 DOI: 10.1016/J.Steroids.2004.01.005  0.484
2004 Zacharia LC, Piché CA, Fielding RM, Holland KM, Allison SD, Dubey RK, Jackson EK. 2-hydroxyestradiol is a prodrug of 2-methoxyestradiol. The Journal of Pharmacology and Experimental Therapeutics. 309: 1093-7. PMID 14872091 DOI: 10.1124/Jpet.103.062505  0.466
2003 Zacharia LC, Gogos JA, Karayiorgou M, Jackson EK, Gillespie DG, Barchiesi F, Dubey RK. Methoxyestradiols mediate the antimitogenic effects of 17beta-estradiol: direct evidence from catechol-O-methyltransferase-knockout mice. Circulation. 108: 2974-8. PMID 14662705 DOI: 10.1161/01.Cir.0000106900.66354.30  0.601
2003 Dubey RK, Zacharia LC, Gillespie DG, Imthurn B, Jackson EK. Catecholamines block the antimitogenic effect of estradiol on human glomerular mesangial cells. Hypertension. 42: 349-55. PMID 12913061 DOI: 10.1161/01.Hyp.0000088320.81260.26  0.616
2003 Zacharia LC, Dubey RK, Mi Z, Jackson EK. Methylation of 2-hydroxyestradiol in isolated organs. Hypertension. 42: 82-7. PMID 12771046 DOI: 10.1161/01.Hyp.0000074702.06466.27  0.541
2003 Dubey RK, Gillespie DG, Zacharia LC, Barchiesi F, Imthurn B, Jackson EK. CYP450- and COMT-derived estradiol metabolites inhibit activity of human coronary artery SMCs. Hypertension. 41: 807-13. PMID 12624000 DOI: 10.1161/01.Hyp.0000048862.28501.72  0.619
2002 Barchiesi F, Jackson EK, Gillespie DG, Zacharia LC, Fingerle J, Dubey RK. Methoxyestradiols mediate estradiol-induced antimitogenesis in human aortic SMCs. Hypertension. 39: 874-9. PMID 11967242 DOI: 10.1161/01.Hyp.0000013863.25970.Ba  0.625
2002 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Catecholamines block 2-hydroxyestradiol-induced antimitogenesis in mesangial cells. Hypertension. 39: 854-9. PMID 11967239 DOI: 10.1161/01.Hyp.0000014502.44988.39  0.586
2002 Dubey RK, Gillespie DG, Keller PJ, Imthurn B, Zacharia LC, Jackson EK. Role of methoxyestradiols in the growth inhibitory effects of estradiol on human glomerular mesangial cells. Hypertension. 39: 418-24. PMID 11882583 DOI: 10.1161/Hy0202.103297  0.606
2002 Dubey RK, Gillespie DG, Zacharia LC, Rosselli M, Imthurn B, Jackson EK. Methoxyestradiols mediate the antimitogenic effects of locally applied estradiol on cardiac fibroblast growth. Hypertension. 39: 412-7. PMID 11882582 DOI: 10.1161/Hy0202.102837  0.585
2002 Tofovic SP, Zacharia L, Carcillo JA, Jackson EK. Inhibition of adenosine deaminase attenuates endotoxin-induced release of cytokines in vivo in rats. Shock (Augusta, Ga.). 16: 196-202. PMID 11531021 DOI: 10.1097/00024382-200116030-00005  0.553
2001 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Catecholamines abrogate antimitogenic effects of 2-hydroxyestradiol on human aortic vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 1745-50. PMID 11701460 DOI: 10.1161/Hq1001.097064  0.619
2001 Dubey RK, Gillespie DG, Zacharia LC, Mi Z, Jackson EK. A(2b) receptors mediate the antimitogenic effects of adenosine in cardiac fibroblasts. Hypertension. 37: 716-21. PMID 11230362 DOI: 10.1161/01.Hyp.37.2.716  0.583
2001 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Increased 2-methoxyestradiol production in human coronary versus aortic vascular cells. Hypertension. 37: 658-62. PMID 11230352 DOI: 10.1161/01.Hyp.37.2.658  0.55
2001 Tofovic SP, Zacharia LC, Carcillo JA, Jackson EK. Inhibition of cytokine release by and cardiac effects of type IV phosphodiesterase inhibition in early, profound endotoxaemia in vivo. Clinical and Experimental Pharmacology & Physiology. 27: 787-92. PMID 11022970 DOI: 10.1046/J.1440-1681.2000.03332.X  0.529
2000 Dubey RK, Gillespie DG, Zacharia LC, Rosselli M, Korzekwa KR, Fingerle J, Jackson EK. Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms. Biochemical and Biophysical Research Communications. 278: 27-33. PMID 11071850 DOI: 10.1006/Bbrc.2000.3755  0.578
2000 Dubey RK, Jackson EK, Gillespie DG, Zacharia LC, Imthurn B, Keller PJ. Clinically used estrogens differentially inhibit human aortic smooth muscle cell growth and mitogen-activated protein kinase activity. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 964-72. PMID 10764660 DOI: 10.1161/01.Atv.20.4.964  0.626
2000 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Increased 2-Methoxyestradiol Production in Human Coronary Artery Versus Aortic Smooth Muscle Cells: Potential Role in Mediating the Cardioprotective Effects of Estradiol Hypertension. 36: 708-708. DOI: 10.1161/01.Hyp.36.Suppl_1.708-C  0.547
2000 Zacharia LC, Jackson EK, Gillespie DG, Dubey RK. Catecholamines Abrogate the Anti-Mitogenic Effects of 2-Hydroxy Metabolite of Estradiol on Vascular Smooth Muscle Cells by Inhibiting Catechol-O-Methyltransferase (COMT) Activity and 2-Methoxyestradiol Formation Hypertension. 36: 705-706. DOI: 10.1161/01.Hyp.36.Suppl_1.705-D  0.593
Show low-probability matches.