Aharon G. Freud, Ph.D. - Publications

Affiliations: 
2006 Ohio State University, Columbus, Columbus, OH 
Area:
Immunology

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hegewisch-Solloa E, Melsen JE, Ravichandran H, Rendeiro AF, Freud AG, Mundy-Bosse B, Melms JC, Eisman SE, Izar B, Grunstein E, Connors TJ, Elemento O, Horowitz A, Mace EM. Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry and high-resolution microscopy. Biorxiv : the Preprint Server For Biology. PMID 37732282 DOI: 10.1101/2023.09.05.556371  0.414
2023 Read KA, Jones DM, Pokhrel S, Hales EDS, Varkey A, Tuazon JA, Eisele CD, Abdouni O, Saadey A, Leonard MR, Warren RT, Powell MD, Boss JM, Hemann EA, Yount JS, ... ... Freud AG, et al. Aiolos represses CD4 T cell cytotoxic programming via reciprocal regulation of T transcription factors and IL-2 sensitivity. Nature Communications. 14: 1652. PMID 36964178 DOI: 10.1038/s41467-023-37420-0  0.318
2023 Hegewisch-Solloa E, Nalin AP, Freud AG, Mace EM. Deciphering the localization and trajectory of human natural killer cell development. Journal of Leukocyte Biology. PMID 36869821 DOI: 10.1093/jleuko/qiad027  0.403
2023 Krämer B, Nalin AP, Ma F, Eickhoff S, Lutz P, Leonardelli S, Goeser F, Finnemann C, Hack G, Raabe J, ToVinh M, Ahmad S, Hoffmeister C, Kaiser KM, Manekeller S, ... ... Freud AG, et al. Single-cell RNA sequencing identifies a population of human liver-type ILC1s. Cell Reports. 42: 111937. PMID 36640314 DOI: 10.1016/j.celrep.2022.111937  0.31
2022 Mundy-Bosse BL, Weigel C, Wu YZ, Abdelbaky S, Youssef Y, Casas SB, Polley N, Ernst G, Young KA, McConnell KK, Nalin AP, Wu KG, Broughton M, Lordo MR, Altynova E, ... ... Freud AG, et al. Identification and Targeting of the Developmental Blockade in Extranodal Natural Killer/T-cell Lymphoma. Blood Cancer Discovery. 3: 154-169. PMID 35247900 DOI: 10.1158/2643-3230.BCD-21-0098  0.813
2021 Chen HZ, Bonneville R, Paruchuri A, Reeser JW, Wing MR, Samorodnitsky E, Krook MA, Smith AM, Dao T, Miya J, Wang W, Yu L, Freud AG, Allenby P, Cole S, et al. Genomic and Transcriptomic Characterization of Relapsed SCLC Through Rapid Research Autopsy. Jto Clinical and Research Reports. 2: 100164. PMID 34590014 DOI: 10.1016/j.jtocrr.2021.100164  0.54
2021 Lordo MR, Wu KG, Altynova E, Shilo N, Kronen P, Nalin AP, Weigel C, Zhang X, Yu J, Oakes CC, Caligiuri MA, Freud AG, Mundy-Bosse BL. Acute Myeloid Leukemia Alters Group 1 Innate Lymphoid Cell Differentiation from a Common Precursor. Journal of Immunology (Baltimore, Md. : 1950). PMID 34417259 DOI: 10.4049/jimmunol.2100023  0.56
2021 Hegewisch-Solloa E, Seo S, Mundy-Bosse BL, Mishra A, Waldman EH, Maurrasse S, Grunstein E, Connors TJ, Freud AG, Mace EM. Differential Integrin Adhesome Expression Defines Human NK Cell Residency and Developmental Stage. Journal of Immunology (Baltimore, Md. : 1950). PMID 34282002 DOI: 10.4049/jimmunol.2100162  0.376
2021 Moreno-Nieves UY, Tay JK, Saumyaa S, Horowitz NB, Shin JH, Mohammad IA, Luca B, Mundy DC, Gulati GS, Bedi N, Chang S, Chen C, Kaplan MJ, Rosenthal EL, Holsinger FC, ... ... Freud AG, et al. Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34244432 DOI: 10.1073/pnas.2101169118  0.412
2021 Lordo MR, Scoville SD, Goel A, Yu J, Freud AG, Caligiuri MA, Mundy-Bosse BL. Unraveling the Role of Innate Lymphoid Cells in AcuteMyeloid Leukemia. Cancers. 13. PMID 33477248 DOI: 10.3390/cancers13020320  0.527
2020 Nalin AP, Kowalski JJ, Sprague AC, Schumacher BK, Gerhardt AG, Youssef Y, Vedantam KV, Zhang X, Siebel CW, Mace EM, Caligiuri MA, Mundy-Bosse BL, Freud AG. Notch Regulates Innate Lymphoid Cell Plasticity during Human NK Cell Development. Journal of Immunology (Baltimore, Md. : 1950). PMID 33020148 DOI: 10.4049/jimmunol.2000434  0.543
2020 Paruchuri A, Chen HZ, Bonneville R, Reeser JW, Wing MR, Krook MA, Samorodnitsky E, Miya J, Dao T, Smith A, Freud AG, Allenby P, Roychowdhury S. Research Autopsy Demonstrates Polyclonal Acquired Resistance in a Patient With Metastatic GI Stromal Tumor. Jco Precision Oncology. 4. PMID 32923900 DOI: 10.1200/PO.19.00328  0.542
2020 Sitnicka E, Bryceson Y, Freud AG, Mace EM. Editorial: Molecular and Cellular Pathways in NK Cell Development. Frontiers in Immunology. 11: 1448. PMID 32760398 DOI: 10.3389/Fimmu.2020.01448  0.411
2020 Braunstein Z, Mishra A, Staub A, Freud AG, Porcu P, Brammer JE. Clinical outcomes in T-cell large granular lymphocytic leukaemia: prognostic factors and treatment response. British Journal of Haematology. PMID 32519348 DOI: 10.1111/Bjh.16808  0.322
2020 Krook MA, Lenyo A, Wilberding M, Barker H, Dantuono M, Bailey KM, Chen HZ, Reeser JW, Wing MR, Miya J, Samorodnitsky E, Smith AM, Dao T, Martin DM, Ciombor KK, ... ... Freud AG, et al. Efficacy of FGFR inhibitors and combination therapies for acquired resistance in FGFR2-fusion cholangiocarcinoma. Molecular Cancer Therapeutics. PMID 31911531 DOI: 10.1158/1535-7163.Mct-19-0631  0.604
2019 Bill M, Pathmanathan A, Karunasiri M, Shen C, Burke MH, Ranganathan P, Papaioannou D, Zitzer NC, Snyder K, LaRocco A, Walker AE, Brannan ZJ, Nalin AP, Freud AG, Dikov MM, et al. EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31672772 DOI: 10.1158/1078-0432.Ccr-19-2479  0.643
2019 Riggan L, Freud AG, O'Sullivan TE. True Detective: Unraveling Group 1 Innate Lymphocyte Heterogeneity. Trends in Immunology. PMID 31500958 DOI: 10.1016/J.It.2019.08.005  0.445
2019 Krook MA, Bonneville R, Chen HZ, Reeser JW, Wing MR, Martin DM, Smith AM, Dao T, Samorodnitsky E, Paruchuri A, Miya J, Baker KR, Yu L, Timmers C, Dittmar K, ... Freud AG, et al. Tumor heterogeneity and acquired drug resistance in FGFR2-fusion-positive cholangiocarcinoma through rapid research autopsy. Cold Spring Harbor Molecular Case Studies. 5. PMID 31371345 DOI: 10.1101/mcs.a004002  0.585
2019 Krook MA, Barker H, Chen HZ, Reeser JW, Wing MR, Martin D, Smith AM, Dao T, Bonneville R, Samorodnitsky E, Miya J, Freud AG, Monk JP, Clinton SK, Roychowdhury S. Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer. Prostate Cancer and Prostatic Diseases. PMID 31043681 DOI: 10.1038/S41391-019-0145-2  0.588
2019 Chen HZ, Bonneville R, Yu L, Wing MR, Reeser JW, Krook MA, Miya J, Samorodnitsky E, Smith A, Martin D, Dao T, Guo Q, Liebner D, Freud AG, Allenby P, et al. Genomic characterization of metastatic ultra-hypermutated interdigitating dendritic cell sarcoma through rapid research autopsy. Oncotarget. 10: 277-288. PMID 30719225 DOI: 10.18632/Oncotarget.26352  0.623
2019 Wang Y, Zhang Y, Yi P, Dong W, Nalin AP, Zhang J, Zhu Z, Chen L, Benson DM, Mundy-Bosse BL, Freud AG, Caligiuri MA, Yu J. The IL-15-AKT-XBP1s signaling pathway contributes to effector functions and survival in human NK cells. Nature Immunology. 20: 10-17. PMID 30538328 DOI: 10.1038/S41590-018-0265-1  0.621
2019 Wang Y, Zhang Y, Yi P, Dong W, Nalin AP, Zhang J, Zhu Z, Chen L, Benson DM, Mundy-Bosse BL, Freud AG, Caligiuri MA, Yu J. The IL-15-AKT-XBP1s signaling pathway contributes to effector functions and survival in human NK cells. Nature Immunology. 20: 10-17. PMID 30538328 DOI: 10.1038/S41590-018-0265-1  0.621
2019 Bill M, Pathmanathan A, Karunasiri M, Shen C, Burke M, Ranganathan P, Papaioannou D, Zitzer NC, Snyder K, LaRocco A, Walker A, Brannan Z, Nalin AP, Freud AG, Dikov M, et al. EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid Leukemia (AML) Blood. 134: 2546-2546. DOI: 10.1182/Blood-2019-131856  0.633
2019 Brammer JE, Boles AE, Mansour A, Freud AG, Mathé-Allainmat M, Quéméner A, Mortier E, Porcu P, Mishra A. Reversible DNA Hypermethylation of the Interleukin-15 (IL-15) Promoter Induces IL-15 Expression, Drives the Pathogenesis of T-Cell Large Granular Lymphocytic Leukemia and Provides a Potential Therapeutic Approach Using 5-Azacitidine Blood. 134: 3776-3776. DOI: 10.1182/Blood-2019-131174  0.53
2019 Weigel C, Mundy-Bosse BL, Wu Y, McConnell K, Mishra A, Caligiuri MA, Baiocchi RA, Natkunam Y, Porcu P, Brammer J, Freud AG, Oakes CC. Abstract LB-102: Extranodal natural killer/T cell lymphoma (ENKTL) exhibits an unprecedented degree of global DNA hypermethylation, providing a potent targeted therapy in vivo Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-Lb-102  0.513
2019 Chen H, Bonneville R, Krook MA, Wing MR, Reeser JW, Miya J, Paruchuri A, Samorodnitsky E, Yu L, Smith AM, Dao T, Martin D, Guo Q, Magenheim H, Freud AG, et al. Abstract 748: Genomic characterization of recurrent small cell lung cancer through research autopsy reveals clonal diversity and candidate driver of chemoresistance Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-748  0.606
2019 Krook MA, Bonneville R, Chen H, Reeser JW, Wing MR, Miya J, Smith AM, Paruchuri A, Dao T, Martin DM, Samorodnitsky E, Baker KR, Timmers C, Dittmar K, Cole S, ... ... Freud AG, et al. Abstract 2909: Rapid autopsy of metastatic cholangiocarcinoma demonstrates diverse patterns of clonal heterogeneity Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2909  0.564
2019 Krook MA, Lenyo AM, Wilberding MJ, Barker HD, Dantuono M, Chen H, Reeser JW, Wing MR, Miya J, Samorodnitsky E, Smith AM, Dao T, Martin DM, Dittmar K, Ciombor KK, ... ... Freud AG, et al. Abstract 335: Efficacy of FGFR inhibitors and combination therapies for acquired resistance in FGFR2-fusion cholangiocarcinoma Cancer Research. 79: 335-335. DOI: 10.1158/1538-7445.Am2019-335  0.622
2019 Brammer J, Braunstein Z, Mishra A, Byrd J, Staub A, Freud A, Baiocchi R, Porcu P. CLINICAL OUTCOMES OF PATIENTS WITH T-CELL LARGE GRANULAR LYMPHOCYTIC LEUKEMIA (T-LGLL) AT THE OHIO STATE UNIVERSITY JAMES COMPREHENSIVE CANCER CENTER (OSU JAMES-CCC) Hematological Oncology. 37: 481-482. DOI: 10.1002/Hon.160_2631  0.332
2018 Scoville SD, Freud AG, Caligiuri MA. Cellular pathways in the development of human and murine innate lymphoid cells. Current Opinion in Immunology. 56: 100-106. PMID 30579240 DOI: 10.1016/J.Coi.2018.11.003  0.577
2018 Chen L, Youssef Y, Robinson C, Ernst GF, Carson MY, Young KA, Scoville SD, Zhang X, Harris R, Sekhri P, Mansour AG, Chan WK, Nalin AP, Mao HC, Hughes T, ... ... Freud AG, et al. CD56 Expression Marks Human Group 2 Innate Lymphoid Cell Divergence from a Shared NK Cell and Group 3 Innate Lymphoid Cell Developmental Pathway. Immunity. PMID 30193847 DOI: 10.1016/J.Immuni.2018.08.010  0.641
2018 Wang Y, Chu J, Yi P, Dong W, Saultz JN, Wang Y, Wang H, Scoville SD, Zhang J, Wu LC, Deng Y, He X, Mundy-Bosse BL, Freud AG, Wang LS, et al. SMAD4 promotes TGF-β-independent NK cell homeostasis and maturation and antitumor immunity. The Journal of Clinical Investigation. PMID 30183689 DOI: 10.1172/Jci121227  0.572
2018 Scoville SD, Nalin AP, Chen L, Chen L, Zhang M, McConnell K, Beceiro Casas S, Ernst G, Traboulsi AA, Hashi N, Williams M, Zhang X, Hughes T, Mishra A, Benson DM, ... ... Freud AG, et al. Human AML activates the AHR pathway to impair NK cell development and function. Blood. PMID 30158248 DOI: 10.1182/Blood-2018-03-838474  0.597
2018 Saultz JN, Freud AG, Mundy-Bosse BL. MicroRNA regulation of natural killer cell development and function in leukemia. Molecular Immunology. PMID 30100210 DOI: 10.1016/J.Molimm.2018.07.022  0.328
2018 Mundy-Bosse B, Denlinger N, McLaughlin E, Chakravarti N, Hwang S, Chen L, Mao HC, Kline D, Youssef Y, Kohnken R, Lee DA, Lozanski G, Freud AG, Porcu P, William B, et al. Highly cytotoxic natural killer cells are associated with poor prognosis in patients with cutaneous T-cell lymphoma. Blood Advances. 2: 1818-1827. PMID 30054309 DOI: 10.1182/Bloodadvances.2018020388  0.671
2018 Hu E, Waibl-Polania J, Frissora F, Beaver LS, Zapolnik K, Mundy-Bosse BL, Mishra A, Freud AG, Yu J, Byrd JC, Oakes CC, Ostrowski M, Muthusamy N. The ETS1 Transcription Factor Is Implicated in Human and Murine Intermediate NK Cell Development Stages Blood. 132: 2567-2567. DOI: 10.1182/Blood-2018-99-115261  0.476
2018 Scoville SD, Nalin A, Chen L, Chen L, McConnell K, Casas SB, Al-Rahman A, Hashi N, Zhang M, Saultz J, Yu J, Freud A, Caligiuri M, Mundy-Bosse B. Abstract 4729: The aryl hydrocarbon receptor directly regulates microRNA-29b to inhibit human natural killer cell development and function in acute myeloid leukemia Cancer Research. 78: 4729-4729. DOI: 10.1158/1538-7445.Am2018-4729  0.601
2018 Kartan S, Denlinger N, McLaughlin E, Chakravarti N, Huang S, Chen L, Mao H, Kline D, Youssef Y, Kohnken R, Young K, Lee D, Lozanski G, Freud A, Porcu P, et al. Enhanced Spontaneous Anti-Tumor Cytotoxicity of Natural Killer Cells in Cutaneous T-Cell Lymphoma Patients Clinical Lymphoma Myeloma and Leukemia. 18: S287-S288. DOI: 10.1016/J.Clml.2018.07.226  0.56
2017 Victor AR, Weigel C, Scoville SD, Chan WK, Chatman K, Nemer MM, Mao C, Young KA, Zhang J, Yu J, Freud AG, Oakes CC, Caligiuri MA. Epigenetic and Posttranscriptional Regulation of CD16 Expression during Human NK Cell Development. Journal of Immunology (Baltimore, Md. : 1950). PMID 29229679 DOI: 10.4049/Jimmunol.1701128  0.603
2017 Freud AG, Mundy-Bosse BL, Yu J, Caligiuri MA. The Broad Spectrum of Human Natural Killer Cell Diversity. Immunity. 47: 820-833. PMID 29166586 DOI: 10.1016/J.Immuni.2017.10.008  0.627
2017 Wing MR, Reeser JW, Smith AM, Reeder M, Martin D, Jewell BM, Datta J, Miya J, Monk JP, Mortazavi A, Otterson GA, Goldberg RM, VanDeusen JB, Cole S, Dittmar K, ... ... Freud AG, et al. Analytic validation and real-time clinical application of an amplicon-based targeted gene panel for advanced cancer. Oncotarget. 8: 75822-75833. PMID 29100271 DOI: 10.18632/Oncotarget.20616  0.73
2017 Andritsos LA, Grieselhuber NR, Anghelina M, Rogers KA, Roychowdhury S, Reeser JW, Timmers CD, Freud AG, Blachly JS, Lucas DM, Lozanski G, Jones JA, Williams K, Oakes C, Jones D, et al. Trametinib for the treatment of IGHV4-34, MAP2K1-mutant variant hairy cell leukemia. Leukemia & Lymphoma. 1-4. PMID 28918710 DOI: 10.1080/10428194.2017.1365853  0.63
2017 Victor AR, Nalin AP, Dong W, McClory S, Wei M, Mao C, Kladney RD, Youssef Y, Chan WK, Briercheck EL, Hughes T, Scoville SD, Pitarresi JR, Chen C, Manz S, ... ... Freud AG, et al. IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-κB. Journal of Immunology (Baltimore, Md. : 1950). PMID 28842466 DOI: 10.4049/Jimmunol.1601554  0.787
2017 Reeser JW, Martin D, Miya J, Kautto EA, Lyon E, Zhu E, Wing MR, Smith A, Reeder M, Samorodnitsky E, Parks H, Naik KR, Gozgit J, Nowacki N, Davies KD, ... ... Freud AG, et al. Validation of a Targeted RNA Sequencing Assay for Kinase Fusion Detection in Solid Tumors. The Journal of Molecular Diagnostics : Jmd. PMID 28802831 DOI: 10.1016/J.Jmoldx.2017.05.006  0.595
2017 Haverkos BM, Coleman C, Gru AA, Pan Z, Brammer J, Rochford R, Mishra A, Oakes CC, Baiocchi RA, Freud AG, Porcu P. Emerging insights on the pathogenesis and treatment of extranodal NK/T cell lymphomas (ENKTL). Discovery Medicine. 23: 189-199. PMID 28472613  0.315
2017 Scoville SD, Freud AG, Caligiuri MA. Modeling Human Natural Killer Cell Development in the Era of Innate Lymphoid Cells. Frontiers in Immunology. 8: 360. PMID 28396671 DOI: 10.3389/Fimmu.2017.00360  0.618
2016 Haverkos BM, Huang Y, Gru A, Pancholi P, Freud AG, Mishra A, Ruppert AS, Baiocchi RA, Porcu P. Frequency and clinical correlates of elevated plasma Epstein-Barr virus DNA at diagnosis in peripheral T-cell lymphomas (PTCL). International Journal of Cancer. PMID 27943278 DOI: 10.1002/Ijc.30566  0.318
2016 Mace EM, Bigley V, Gunesch JT, Chinn IK, Angelo LS, Care MA, Maisuria S, Keller MD, Togi S, Watkin LB, LaRosa DF, Jhangiani SN, Muzny DM, Stray-Pedersen A, Coban Akdemir Z, ... ... Freud AG, et al. Biallelic mutations in IRF8 impair human NK cell maturation and function. The Journal of Clinical Investigation. PMID 27893462 DOI: 10.1172/Jci86276  0.607
2016 Haverkos BM, Pan Z, Gru AA, Freud AG, Rabinovitch R, Xu-Welliver M, Otto B, Barrionuevo C, Baiocchi RA, Rochford R, Porcu P. Extranodal NK/T Cell Lymphoma, Nasal Type (ENKTL-NT): An Update on Epidemiology, Clinical Presentation, and Natural History in North American and European Cases. Current Hematologic Malignancy Reports. PMID 27778143 DOI: 10.1007/S11899-016-0355-9  0.341
2016 Mundy-Bosse BL, Scoville SD, Chen L, McConnell K, Mao HC, Ahmed EH, Zorko N, Harvey S, Cole J, Zhang X, Costinean S, Croce CM, Larkin K, Byrd JC, Vasu S, ... ... Freud AG, et al. MicroRNA-29b mediates altered innate immune development in acute leukemia. The Journal of Clinical Investigation. PMID 27775550 DOI: 10.1172/Jci85413  0.611
2016 Haverkos BM, Gru AA, Geyer SM, Bingman AK, Hemminger JA, Mishra A, Wong HK, Pancholi P, Freud AG, Caligiuri MA, Baiocchi RA, Porcu P. Increased Levels of Plasma Epstein Barr Virus DNA Identify a Poor-Risk Subset of Patients With Advanced Stage Cutaneous T-Cell Lymphoma. Clinical Lymphoma, Myeloma & Leukemia. 16: S181-S190.e4. PMID 27521316 DOI: 10.1016/J.Clml.2016.02.014  0.485
2016 Freud AG, Keller KA, Scoville SD, Mundy-Bosse BL, Cheng S, Youssef Y, Hughes T, Zhang X, Mo X, Porcu P, Baiocchi RA, Yu J, Carson WE, Caligiuri MA. NKp80 Defines a Critical Step during Human Natural Killer Cell Development. Cell Reports. PMID 27373165 DOI: 10.1016/J.Celrep.2016.05.095  0.588
2016 Scoville SD, Mundy-Bosse BL, Zhang MH, Chen L, Zhang X, Keller KA, Hughes T, Chen L, Cheng S, Bergin SM, Mao HC, McClory S, Yu J, Carson WE, Caligiuri MA, ... Freud AG, et al. A Progenitor Cell Expressing Transcription Factor RORγt Generates All Human Innate Lymphoid Cell Subsets. Immunity. PMID 27178467 DOI: 10.1016/J.Immuni.2016.04.007  0.805
2016 Johnson RC, Kim J, Natkunam Y, Sundram U, Freud AG, Gammon B, Cascio MJ. Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Extramedullary Presentations of Myeloid Leukemia From Blastic Plasmacytoid Dendritic Cell Neoplasm. The American Journal of Surgical Pathology. PMID 26796502 DOI: 10.1097/Pas.0000000000000595  0.369
2015 Gru AA, Haverkos BH, Freud AG, Hastings J, Nowacki NB, Barrionuevo C, Vigil CE, Rochford R, Natkunam Y, Baiocchi RA, Porcu P. The Epstein-Barr Virus (EBV) in T Cell and NK Cell Lymphomas: Time for a Reassessment. Current Hematologic Malignancy Reports. PMID 26449716 DOI: 10.1007/S11899-015-0292-Z  0.453
2015 Scoville SD, Keller KA, Cheng S, Zhang M, Zhang X, Caligiuri MA, Freud AG. Rapid Column-Free Enrichment of Mononuclear Cells from Solid Tissues. Scientific Reports. 5: 12490. PMID 26223896 DOI: 10.1038/Srep12490  0.481
2015 Deng Y, Kerdiles Y, Chu J, Yuan S, Wang Y, Chen X, Mao H, Zhang L, Zhang J, Hughes T, Deng Y, Zhang Q, Wang F, Zou X, Liu CG, ... Freud AG, et al. Transcription factor Foxo1 is a negative regulator of natural killer cell maturation and function. Immunity. 42: 457-70. PMID 25769609 DOI: 10.1016/J.Immuni.2015.02.006  0.602
2015 Scoville S, Mundy-Bosse B, Zhang M, Chen L, Sanderson R, Hughes T, Garzon R, Mishra A, Costinean S, Croce CM, Freud AG, Caligiuri MA. Microrna 29b Mediates Immune Evasion of Natural Killer Cells in Acute Myeloid Leukemia Blood. 126: 207-207. DOI: 10.1182/Blood.V126.23.207.207  0.59
2014 Hughes T, Briercheck EL, Freud AG, Trotta R, McClory S, Scoville SD, Keller K, Deng Y, Cole J, Harrison N, Mao C, Zhang J, Benson DM, Yu J, Caligiuri MA. The transcription Factor AHR prevents the differentiation of a stage 3 innate lymphoid cell subset to natural killer cells. Cell Reports. 8: 150-62. PMID 24953655 DOI: 10.1016/J.Celrep.2014.05.042  0.821
2014 Metcalf RA, Monabati A, Vyas M, Roncador G, Gualco G, Bacchi CE, Younes SF, Natkunam Y, Freud AG. Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma. Human Pathology. 45: 1730-6. PMID 24925224 DOI: 10.1016/J.Humpath.2014.04.004  0.379
2014 Freud AG, Yu J, Caligiuri MA. Human natural killer cell development in secondary lymphoid tissues. Seminars in Immunology. 26: 132-7. PMID 24661538 DOI: 10.1016/J.Smim.2014.02.008  0.593
2014 Mundy-Bosse B, Kathleen M, Mao C, Ahmed E, Chen L, Scoville SD, Freud AG, Yu J, Caligiuri MA. Acute Myeloid Leukemia Alters Natural Killer Cell Maturation and Functional Activation Blood. 124: 754-754. DOI: 10.1182/Blood.V124.21.754.754  0.616
2014 Scoville SD, Keller K, Mundy-Bosse B, Caligiuri MA, Freud AG. A Novel CD94+ Immature NK Cell Population Based on NKp80 Expression with ILC3-like Features in Human Secondary Lymphoid Tissue Blood. 124: 751-751. DOI: 10.1182/Blood.V124.21.751.751  0.65
2013 Freud AG, Zhao S, Wei S, Gitana GM, Molina-Kirsch HF, Atwater SK, Natkunam Y. Expression of the activating receptor, NKp46 (CD335), in human natural killer and T-cell neoplasia. American Journal of Clinical Pathology. 140: 853-66. PMID 24225754 DOI: 10.1309/Ajcpwgg69Mczowmm  0.436
2013 Yu J, Freud AG, Caligiuri MA. Location and cellular stages of natural killer cell development. Trends in Immunology. 34: 573-82. PMID 24055329 DOI: 10.1016/J.It.2013.07.005  0.608
2012 Anderson MW, Zhao S, Freud AG, Czerwinski DK, Kohrt H, Alizadeh AA, Houot R, Azambuja D, Biasoli I, Morais JC, Spector N, Molina-Kirsch HF, Warnke RA, Levy R, Natkunam Y. CD137 is expressed in follicular dendritic cell tumors and in classical Hodgkin and T-cell lymphomas: diagnostic and therapeutic implications. The American Journal of Pathology. 181: 795-803. PMID 22901750 DOI: 10.1016/J.Ajpath.2012.05.015  0.481
2012 Cubedo E, Gentles AJ, Huang C, Natkunam Y, Bhatt S, Lu X, Jiang X, Romero-Camarero I, Freud A, Zhao S, Bacchi CE, Martínez-Climent JA, Sánchez-García I, Melnick A, Lossos IS. Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma. Blood. 119: 5478-91. PMID 22517897 DOI: 10.1182/Blood-2012-01-403154  0.394
2012 McClory S, Hughes T, Freud AG, Briercheck EL, Martin C, Trimboli AJ, Yu J, Zhang X, Leone G, Nuovo G, Caligiuri MA. Evidence for a stepwise program of extrathymic T cell development within the human tonsil. The Journal of Clinical Investigation. 122: 1403-15. PMID 22378041 DOI: 10.1172/Jci46125  0.78
2010 Smith MA, Maurin M, Cho HI, Becknell B, Freud AG, Yu J, Wei S, Djeu J, Celis E, Caligiuri MA, Wright KL. PRDM1/Blimp-1 controls effector cytokine production in human NK cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 6058-67. PMID 20944005 DOI: 10.4049/Jimmunol.1001682  0.548
2010 Hughes T, Becknell B, Freud AG, McClory S, Briercheck E, Yu J, Mao C, Giovenzana C, Nuovo G, Wei L, Zhang X, Gavrilin MA, Wewers MD, Caligiuri MA. Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue. Immunity. 32: 803-14. PMID 20620944 DOI: 10.1016/J.Immuni.2010.06.007  0.807
2010 Guimond M, Freud AG, Mao HC, Yu J, Blaser BW, Leong JW, Vandeusen JB, Dorrance A, Zhang J, Mackall CL, Caligiuri MA. In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasis. Journal of Immunology (Baltimore, Md. : 1950). 184: 2769-75. PMID 20142363 DOI: 10.4049/Jimmunol.0900685  0.84
2010 Freud AG, Caligiuri MA. Purification of human NK cell developmental intermediates from lymph nodes and tonsils. Methods in Molecular Biology (Clifton, N.J.). 612: 1-14. PMID 20033630 DOI: 10.1007/978-1-60761-362-6_1  0.588
2009 Hughes T, Becknell B, McClory S, Briercheck E, Freud AG, Zhang X, Mao H, Nuovo G, Yu J, Caligiuri MA. Stage 3 immature human natural killer cells found in secondary lymphoid tissue constitutively and selectively express the TH 17 cytokine interleukin-22. Blood. 113: 4008-10. PMID 19244159 DOI: 10.1182/Blood-2008-12-192443  0.817
2009 Benson DM, Yu J, Becknell B, Wei M, Freud AG, Ferketich AK, Trotta R, Perrotti D, Briesewitz R, Caligiuri MA. Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells. Blood. 113: 2706-14. PMID 19060242 DOI: 10.1182/Blood-2008-05-159285  0.687
2008 Hughes TL, Becknell MB, Freud A, Schmidt SE, Yu J, Mao C, Gavrilin M, Wewers M, Caligiuri MA. The Stage-Specific Effect of Interleukin-1 Beta (IL-1β) during Human Natural Killer Cell Development Blood. 112: 3746-3746. DOI: 10.1182/blood.v112.11.3746.3746  0.598
2007 Becknell B, Hughes TL, Freud AG, Blaser BW, Yu J, Trotta R, Mao HC, Caligiuri de Jesús ML, Alghothani M, Benson DM, Lehman A, Jarjoura D, Perrotti D, Bates MD, Caligiuri MA. Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells. Blood. 109: 2481-7. PMID 17110450 DOI: 10.1182/Blood-2006-10-050096  0.569
2007 Guimond M, Freud AG, Mao HC, Blaser BW, Lagemann GG, Vandeusen JB, Dorrance A, Ferketich AK, Cavalcanti M, Mackall CL, Caligiuri MA. Mechanism by Which Exogenous Administration of Flt3 Ligand (FL) Expands Natural Killer Cells In Vivo. Blood. 110: 2310-2310. DOI: 10.1182/Blood.V110.11.2310.2310  0.844
2006 Freud AG, Caligiuri MA. Human natural killer cell development. Immunological Reviews. 214: 56-72. PMID 17100876 DOI: 10.1111/J.1600-065X.2006.00451.X  0.612
2006 Shah MH, Freud AG, Benson DM, Ferkitich AK, Dezube BJ, Bernstein ZP, Caligiuri MA. A phase I study of ultra low dose interleukin-2 and stem cell factor in patients with HIV infection or HIV and cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3993-6. PMID 16818697 DOI: 10.1158/1078-0432.Ccr-06-0268  0.647
2006 Freud AG, Yokohama A, Becknell B, Lee MT, Mao HC, Ferketich AK, Caligiuri MA. Evidence for discrete stages of human natural killer cell differentiation in vivo. The Journal of Experimental Medicine. 203: 1033-43. PMID 16606675 DOI: 10.1084/Jem.20052507  0.627
2006 Benson DM, Shah M, Freud A, Ferketich A, Dezube BJ, Bernstein ZP, Caligiuri MA. A phase I study of ultra low dose interleukin-2 (IL-2) and stem cell factor (SCF) in patients with cancer and or HIV infection Journal of Clinical Oncology. 24: 2503-2503. DOI: 10.1200/Jco.2006.24.18_Suppl.2503  0.567
2005 Roychowdhury S, Blaser BW, Freud AG, Katz K, Bhatt D, Ferketich AK, Bergdall V, Kusewitt D, Baiocchi RA, Caligiuri MA. IL-15 but not IL-2 rapidly induces lethal xenogeneic graft-versus-host disease. Blood. 106: 2433-5. PMID 15976176 DOI: 10.1182/Blood-2005-04-1597  0.761
2005 Freud AG, Becknell B, Roychowdhury S, Mao HC, Ferketich AK, Nuovo GJ, Hughes TL, Marburger TB, Sung J, Baiocchi RA, Guimond M, Caligiuri MA. A human CD34(+) subset resides in lymph nodes and differentiates into CD56bright natural killer cells. Immunity. 22: 295-304. PMID 15780987 DOI: 10.1016/J.Immuni.2005.01.013  0.786
2004 Roychowdhury S, May KF, Tzou KS, Lin T, Bhatt D, Freud AG, Guimond M, Ferketich AK, Liu Y, Caligiuri MA. Failed adoptive immunotherapy with tumor-specific T cells: reversal with low-dose interleukin 15 but not low-dose interleukin 2. Cancer Research. 64: 8062-7. PMID 15520217 DOI: 10.1158/0008-5472.Can-04-1860  0.753
2004 Roychowdhury S, Baiocchi RA, Vourganti S, Bhatt D, Blaser BW, Freud AG, Chou J, Chen CS, Xiao JJ, Parthun M, Chan KK, Eisenbeis CF, Ferketich AK, Grever MR, Chen CS, et al. Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder. Journal of the National Cancer Institute. 96: 1447-57. PMID 15467034 DOI: 10.1093/Jnci/Djh271  0.663
2004 Freud AG, Becknell B, Roychowdhury S, Mao HC, Ferketich AK, Nuovo GJ, Hughes TL, Marburger TB, Sung J, Baiocchi RA, Guimond M, Caligiuri MA. A Novel Human CD34(+) Subset That Constitutively Expresses the High Affinity Interleukin-2 Receptor Traffics to Lymph Nodes and Differentiates into CD56Bright Natural Killer Cells. Blood. 104: 314-314. DOI: 10.1182/Blood.V104.11.314.314  0.804
2001 Fehniger TA, Suzuki K, VanDeusen JB, Cooper MA, Freud AG, Caligiuri MA. Fatal leukemia in interleukin-15 transgenic mice. Blood Cells, Molecules & Diseases. 27: 223-30. PMID 11358383 DOI: 10.1006/Bcmd.2001.0379  0.811
2001 Fehniger TA, Suzuki K, Ponnappan A, VanDeusen JB, Cooper MA, Florea SM, Freud AG, Robinson ML, Durbin J, Caligiuri MA. Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells. The Journal of Experimental Medicine. 193: 219-31. PMID 11208862 DOI: 10.1084/Jem.193.2.219  0.821
2001 Whitman SP, Strout MP, Marcucci G, Freud AG, Culley LL, Zeleznik-Le NJ, Mrózek K, Theil KS, Kees UR, Bloomfield CD, Caligiuri MA. The partial nontandem duplication of the MLL (ALL1) gene is a novel rearrangement that generates three distinct fusion transcripts in B-cell acute lymphoblastic leukemia. Cancer Research. 61: 59-63. PMID 11196198  0.413
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