| Year |
Citation |
Score |
| 2017 |
El-Bizri N, Xie C, Liu L, Limberis J, Krause M, Hirakawa R, Nguyen S, Tabuena DR, Belardinelli L, Kahlig KM. Eleclazine exhibits enhanced selectivity for LQT3-associated late INa. Heart Rhythm. PMID 29017927 DOI: 10.1016/J.Hrthm.2017.09.028 |
0.301 |
|
| 2017 |
El-Bizri N, Li CH, Liu GX, Rajamani S, Belardinelli L. Selective Inhibition of Physiological Late Sodium Current Stabilizes Ventricular Repolarization. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00071.2017. PMID 28971840 DOI: 10.1152/Ajpheart.00071.2017 |
0.354 |
|
| 2016 |
Yang PC, El-Bizri N, Romero L, Giles WR, Rajamani S, Belardinelli L, Clancy CE. A computational model predicts adjunctive pharmacotherapy for cardiac safety via selective inhibition of the late cardiac Na current. Journal of Molecular and Cellular Cardiology. PMID 27545042 DOI: 10.1016/J.Yjmcc.2016.08.011 |
0.324 |
|
| 2016 |
Rajamani S, Liu G, El-Bizri N, Guo D, Li C, Chen XL, Kahlig K, Mollova N, Elzein E, Zablocki J, Belardinelli L. The novel late Na(+) current inhibitor, GS-6615 (eleclazine) and its anti-arrhythmic effects in rabbit isolated heart preparations. British Journal of Pharmacology. PMID 27449698 DOI: 10.1111/Bph.13563 |
0.334 |
|
| 2015 |
Kornyeyev D, El-Bizri N, Hirakawa R, Nguyen S, Viatchenko-Karpinski S, Yao L, Rajamani S, Belardinelli L. Contribution of the late sodium current to intracellular sodium and calcium overload in rabbit ventricular myocytes treated by anemone toxin. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00520.2015. PMID 26637557 DOI: 10.1152/Ajpheart.00520.2015 |
0.39 |
|
| 2014 |
Viatchenko-Karpinski S, Kornyeyev D, El-Bizri N, Budas G, Fan P, Jiang Z, Yang J, Anderson ME, Shryock JC, Chang CP, Belardinelli L, Yao L. Intracellular Na+ overload causes oxidation of CaMKII and leads to Ca2+ mishandling in isolated ventricular myocytes. Journal of Molecular and Cellular Cardiology. 76: 247-56. PMID 25252177 DOI: 10.1016/J.Yjmcc.2014.09.009 |
0.532 |
|
| 2014 |
El-Bizri N, Nguyen S, Liu G, Belardinelli L, Rajamani S. Selective Inhibition of Late Na+ Current Reduces Arrhythmic Activity in Spontaneously Hypertensive Rat Myocytes Biophysical Journal. 106: 3-8. DOI: 10.1016/J.Bpj.2013.11.1885 |
0.396 |
|
| 2013 |
Aistrup GL, Gupta DK, Kelly JE, O'Toole MJ, Nahhas A, Chirayil N, Misener S, Beussink L, Singh N, Ng J, Reddy M, Mongkolrattanothai T, El-Bizri N, Rajamani S, Shryock JC, et al. Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1068-79. PMID 23873796 DOI: 10.1152/Ajpheart.00401.2013 |
0.571 |
|
| 2013 |
Spiekerkoetter E, Tian X, Cai J, Hopper RK, Sudheendra D, Li CG, El-Bizri N, Sawada H, Haghighat R, Chan R, Haghighat L, de Jesus Perez V, Wang L, Reddy S, Zhao M, et al. FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension. The Journal of Clinical Investigation. 123: 3600-13. PMID 23867624 DOI: 10.1172/Jci65592 |
0.32 |
|
| 2013 |
Belardinelli L, Liu G, Smith-Maxwell C, Wang WQ, El-Bizri N, Hirakawa R, Karpinski S, Li CH, Hu L, Li XJ, Crumb W, Wu L, Koltun D, Zablocki J, Yao L, et al. A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias. The Journal of Pharmacology and Experimental Therapeutics. 344: 23-32. PMID 23010360 DOI: 10.1124/Jpet.112.198887 |
0.406 |
|
| 2013 |
El-Bizri N, Li H, Liu G, Rajamani S, Belardinelli L. Selective Inhibition of Endogenous Late Na+ Current Stabilizes Cardiac Repolarization and Prevents Arrhythmogenicity Heart Rhythm. 10: 1744. DOI: 10.1016/J.Hrthm.2013.09.023 |
0.347 |
|
| 2012 |
Hirakawa R, El-Bizri N, Shryock JC, Belardinelli L, Rajamani S. Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine. Neuropharmacology. 62: 2251-60. PMID 22313527 DOI: 10.1016/J.Neuropharm.2012.01.021 |
0.337 |
|
| 2011 |
El-Bizri N, Kahlig KM, Shyrock JC, George AL, Belardinelli L, Rajamani S. Ranolazine block of human Na v 1.4 sodium channels and paramyotonia congenita mutants. Channels (Austin, Tex.). 5: 161-72. PMID 21317558 DOI: 10.4161/Chan.5.2.14851 |
0.343 |
|
| 2010 |
El-Bizri N, Shryock JC, George AL, Belardinelli L, Rajamani S. Use-Dependent Block of Nav1.4 Human Paramyotonia Congenita Mutation By Ranolazine Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.049 |
0.349 |
|
| 2009 |
Rajamani S, El-Bizri N, Shryock JC, Makielski JC, Belardinelli L. Use-dependent block of cardiac late Na(+) current by ranolazine. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 1625-31. PMID 19879541 DOI: 10.1016/J.Hrthm.2009.07.042 |
0.365 |
|
| 2009 |
Guignabert C, Alvira CM, Alastalo T, Sawada H, Hansmann G, Zhao M, Wang L, El-Bizri N, Rabinovitch M. Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization American Journal of Physiology-Lung Cellular and Molecular Physiology. 297. PMID 19801450 DOI: 10.1152/Ajplung.00199.2009 |
0.347 |
|
| 2008 |
El-Bizri N, Wang L, Merklinger SL, Guignabert C, Desai T, Urashima T, Sheikh AY, Knutsen RH, Mecham RP, Mishina Y, Rabinovitch M. Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling. Circulation Research. 102: 380-8. PMID 18079409 DOI: 10.1161/Circresaha.107.161059 |
0.325 |
|
| 2005 |
Bkaily G, El-Bizri N, Nader M, Hazzouri KM, Riopel J, Jacques D, Regoli D, D'Orleans-Juste P, Gobeil F, Avedanian L. Angiotensin II induced increase in frequency of cytosolic and nuclear calcium waves of heart cells via activation of AT1 and AT2 receptors. Peptides. 26: 1418-26. PMID 15876474 DOI: 10.1016/J.Peptides.2005.03.051 |
0.65 |
|
| 2003 |
El-Bizri N, Bkaily G, Wang S, Jacques D, Regoli D, D'Orléans-Juste P, Sukarieh R. Bradykinin induced a positive chronotropic effect via stimulation of T- and L-type calcium currents in heart cells. Canadian Journal of Physiology and Pharmacology. 81: 247-58. PMID 12733823 DOI: 10.1139/Y03-045 |
0.696 |
|
| 2003 |
Bkaily G, El-Bizri N, Bui M, Sukarieh R, Jacques D, Fu ML. Modulation of intracellular Ca2+ via L-type calcium channels in heart cells by the autoantibody directed against the second extracellular loop of the alpha1-adrenoceptors. Canadian Journal of Physiology and Pharmacology. 81: 234-46. PMID 12733822 DOI: 10.1139/Y03-044 |
0.687 |
|
| 2000 |
Bkaily G, Choufani S, Hassan G, El-Bizri N, Jacques D, D'Orléans-Juste P. Presence of functional endothelin-1 receptors in nuclear membranes of human aortic vascular smooth muscle cells. Journal of Cardiovascular Pharmacology. 36: S414-7. PMID 11078437 DOI: 10.1097/00005344-200036051-00121 |
0.672 |
|
| 2000 |
Sabra R, Khoury HA, Bechara G, Sharaf LH, El-Bizri NM. Post-junctional mechanisms involved in the potentiation of cardiac adrenergic responses by cocaine European Journal of Pharmacology. 397: 139-150. PMID 10844108 DOI: 10.1016/S0014-2999(00)00192-8 |
0.314 |
|
| 2000 |
Jacques D, Sader S, El-Bizri N, Chouffani S, Hassan G, Shbaklo H. Neuropeptide Y induced increase of cytosolic and nuclear Ca2+ in heart and vascular smooth muscle cells. Canadian Journal of Physiology and Pharmacology. 78: 162-72. PMID 10737679 DOI: 10.1139/Y99-127 |
0.63 |
|
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