William E. Louch, Ph.D. - Publications

Affiliations: 
2001 Dalhousie University, Halifax, Nova Scotia, Canada 
Area:
Pharmacology, Cell Biology, Animal Physiology Biology

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang X, Wu Y, Smith C, Louch WE, Morotti S, Dobrev D, Grandi E, Ni H. Enhanced Ca2+-Driven Arrhythmias in Female Patients with Atrial Fibrillation: Insights from Computational Modeling. Biorxiv : the Preprint Server For Biology. PMID 38496584 DOI: 10.1101/2024.03.04.583217  0.374
2023 Lunde PK, Manfra O, Støle TP, Lunde M, Martinsen M, Carlson CR, Louch WE. Polyarginine Cell-Penetrating Peptides Bind and Inhibit SERCA2. Cells. 12. PMID 37830576 DOI: 10.3390/cells12192358  0.392
2023 Gamage TH, Grabmayr H, Horvath F, Fahrner M, Misceo D, Louch WE, Gunnes G, Pullisaar H, Reseland JE, Lyngstadaas SP, Holmgren A, Amundsen SS, Rathner P, Cerofolini L, Ravera E, et al. A single amino acid deletion in the ER Ca sensor STIM1 reverses the in vitro and in vivo effects of the Stormorken syndrome-causing R304W mutation. Science Signaling. 16: eadd0509. PMID 36749824 DOI: 10.1126/scisignal.add0509  0.332
2022 Zhang X, Smith CER, Morotti S, Edwards AG, Sato D, Louch WE, Ni H, Grandi E. Mechanisms of spontaneous Ca release-mediated arrhythmia in a novel 3D human atrial myocyte model: II. Ca -handling protein variation. The Journal of Physiology. PMID 36114707 DOI: 10.1113/JP283602  0.457
2022 Zhang X, Ni H, Morotti S, Smith CER, Sato D, Louch WE, Edwards AG, Grandi E. Mechanisms of spontaneous Ca release-mediated arrhythmia in a novel 3D human atrial myocyte model: I. Transverse-axial tubule variation. The Journal of Physiology. PMID 36094888 DOI: 10.1113/JP283363  0.488
2022 Shen X, van den Brink J, Bergan-Dahl A, Kolstad TR, Norden ES, Hou Y, Laasmaa M, Aguilar-Sanchez Y, Quick AP, Espe EKS, Sjaastad I, Wehrens XHT, Edwards AG, Soeller C, Louch WE. Prolonged β-adrenergic stimulation disperses ryanodine receptor clusters in cardiomyocytes. Elife. 11. PMID 35913125 DOI: 10.7554/eLife.77725  0.34
2022 Hernández Mesa M, van den Brink J, Louch WE, McCabe KJ, Rangamani P. Nanoscale organization of ryanodine receptor distribution and phosphorylation pattern determines the dynamics of calcium sparks. Plos Computational Biology. 18: e1010126. PMID 35666763 DOI: 10.1371/journal.pcbi.1010126  0.301
2022 Sommese LM, Racioppi MF, Shen X, Orlowski A, Valverde CA, Louch WE, Vila Petroff M, Gonano LA. Discordant Ca release in cardiac myocytes: characterization and susceptibility to pharmacological RyR2 modulation. Pflugers Archiv : European Journal of Physiology. PMID 35235009 DOI: 10.1007/s00424-022-02678-8  0.498
2021 Zhou J, Singh N, Monnier C, Marszalec W, Gao L, Jin J, Frisk M, Louch WE, Verma S, Krishnamurthy P, Nico E, Mulla M, Aistrup GL, Kishore R, Wasserstrom JA. Phosphatidylinositol-4,5-Bisphosphate Binding to Amphiphysin-II Modulates T-Tubule Remodeling: Implications for Heart Failure. Frontiers in Physiology. 12: 782767. PMID 35002765 DOI: 10.3389/fphys.2021.782767  0.312
2021 Edwards AG, Mørk H, Stokke MK, Lipsett DB, Sjaastad I, Richard S, Sejersted OM, Louch WE. Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse. Frontiers in Physiology. 12: 744730. PMID 34712150 DOI: 10.3389/fphys.2021.744730  0.5
2021 Setterberg IE, Le C, Frisk M, Li J, Louch WE. The Physiology and Pathophysiology of T-Tubules in the Heart. Frontiers in Physiology. 12: 718404. PMID 34566684 DOI: 10.3389/fphys.2021.718404  0.372
2021 Grote Beverborg N, Später D, Knöll R, Hidalgo A, Yeh ST, Elbeck Z, Silljé HHW, Eijgenraam TR, Siga H, Zurek M, Palmér M, Pehrsson S, Albery T, Bomer N, Hoes MF, ... ... Louch WE, et al. Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy. Nature Communications. 12: 5180. PMID 34462437 DOI: 10.1038/s41467-021-25439-0  0.342
2021 Sadredini M, Haugsten Hansen M, Frisk M, Louch WE, Lehnart SE, Sjaastad I, Stokke MK. CaMKII inhibition has dual effects on spontaneous Ca release and Ca alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34270372 DOI: 10.1152/ajpheart.00011.2021  0.488
2021 Yamakawa S, Wu D, Dasgupta M, Pedamallu H, Gupta B, Modi R, Mufti M, O'Callaghan C, Frisk M, Louch WE, Arora R, Shiferaw Y, Burrell A, Ryan J, Nelson L, et al. Role of T-Tubule Remodeling on Mechanisms of Abnormal Calcium Release During Heart Failure Development in Canine Ventricle. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33635163 DOI: 10.1152/ajpheart.00946.2020  0.491
2020 Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK. Exercise Training Stabilizes RyR2-Dependent Ca Release in Post-infarction Heart Failure. Frontiers in Cardiovascular Medicine. 7: 623922. PMID 33569394 DOI: 10.3389/fcvm.2020.623922  0.457
2020 Tazmini K, Frisk M, Lewalle A, Laasmaa M, Morotti S, Lipsett DB, Manfra O, Skogestad J, Aronsen JM, Sejersted OM, Sjaastad I, Edwards AG, Grandi E, Niederer SA, Oie E, ... Louch WE, et al. Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes. Circulation Research. PMID 32070187 DOI: 10.1161/CIRCRESAHA.119.315641  0.477
2019 Shiferaw Y, Aistrup GL, Louch WE, Wasserstrom JA. Remodeling Promotes Proarrhythmic Disruption of Calcium Homeostasis in Failing Atrial Myocytes. Biophysical Journal. PMID 31889516 DOI: 10.1016/J.Bpj.2019.12.012  0.424
2019 Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, ... ... Louch WE, et al. Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca-Dependent Arrhythmia. Circulation. Arrhythmia and Electrophysiology. 12: e007045. PMID 30943765 DOI: 10.1161/CIRCEP.118.007045  0.375
2019 Lipsett DB, Frisk M, Aronsen JM, Nordén ES, Buonarati OR, Cataliotti A, Hell JW, Sjaastad I, Christensen G, Louch WE. Cardiomyocyte substructure reverts to an immature phenotype during heart failure. The Journal of Physiology. 597: 1833-1853. PMID 30707448 DOI: 10.1113/JP277273  0.377
2018 Kolstad TR, van den Brink J, MacQuaide N, Lunde PK, Frisk M, Aronsen JM, Norden ES, Cataliotti A, Sjaastad I, Sejersted OM, Edwards AG, Lines GT, Louch WE. Ryanodine receptor dispersion disrupts Ca release in failing cardiac myocytes. Elife. 7. PMID 30375974 DOI: 10.7554/eLife.39427  0.482
2017 Parikh SS, Blackwell DJ, Gomez-Hurtado N, Frisk M, Wang L, Kim K, Dahl CP, Fiane AE, Tønnessen T, Kryshtal DO, Louch WE, Knollmann BC. Thyroid and Glucocorticoid Hormones Promote Functional T-tubule Development in Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes. Circulation Research. PMID 28974554 DOI: 10.1161/CIRCRESAHA.117.311920  0.373
2017 Lubelwana Hafver T, Wanichawan P, Manfra O, de Souza GA, Lunde M, Martinsen M, Louch WE, Sejersted OM, Carlson CR. Mapping the in vitro interactome of cardiac sodium (Na )-calcium (Ca ) exchanger 1 (NCX1). Proteomics. 17. PMID 28755400 DOI: 10.1002/pmic.201600417  0.338
2017 Gattoni S, Treu Røe Å, Aronsen JM, Sjaastad I, Louch WE, Smith NP, Niederer SA. Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding. The Journal of Physiology. PMID 28542952 DOI: 10.1113/JP273879  0.466
2017 Røe ÅT, Aronsen JM, Skårdal K, Hamdani N, Linke WA, Danielsen HE, Sejersted OM, Sjaastad I, Louch WE. Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy. Cardiovascular Research. PMID 28472418 DOI: 10.1093/cvr/cvx087  0.347
2016 Aronsen JM, Louch WE, Sjaastad I. Cardiomyocyte Ca2+ dynamics: clinical perspectives. Scandinavian Cardiovascular Journal : Scj. 50: 65-77. PMID 26729487 DOI: 10.3109/14017431.2015.1136079  0.477
2015 Curran J, Louch WE. Linking ryanodine receptor Ca(2+) leak and Na(+) current in heart: a day in the life of flecainide. Acta Physiologica (Oxford, England). 214: 300-2. PMID 25976700 DOI: 10.1111/apha.12526  0.396
2015 Aronsen JM, Skogestad J, Lewalle A, Louch WE, Hougen K, Stokke MK, Swift F, Niederer S, Smith NP, Sejersted OM, Sjaastad I. Hypokalaemia induces Ca(2+) overload and Ca(2+) waves in ventricular myocytes by reducing Na(+),K(+)-ATPase α2 activity. The Journal of Physiology. 593: 1509-21. PMID 25772299 DOI: 10.1113/jphysiol.2014.279893  0.443
2015 Louch WE, Koivumäki JT, Tavi P. Calcium signalling in developing cardiomyocytes: implications for model systems and disease. The Journal of Physiology. 593: 1047-63. PMID 25641733 DOI: 10.1113/jphysiol.2014.274712  0.412
2015 Roe AT, Frisk M, Louch WE. Targeting cardiomyocyte Ca2+ homeostasis in heart failure. Current Pharmaceutical Design. 21: 431-48. PMID 25483944 DOI: 10.2174/138161282104141204124129  0.411
2015 Frisk M, Espe EK, Røe ÅT, Aronsen JM, Zhang L, Enger UH, Sejersted OM, Sjaastad I, Sjaastad I, Louch WE. Ventricular Wall Stress Predicts Disruption of Cardiomyocyte T-Tubule Structure and Ca2+ Homeostasis across the Infarcted Heart Biophysical Journal. 108: 106a. DOI: 10.1016/j.bpj.2014.11.602  0.38
2014 Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaløy H, Louch WE, Tønnessen T, Sjaastad I, Sejersted OM, Carlson CR. Molecular basis of Calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure Journal of Biological Chemistry. 289: 33984-33998. PMID 25336645 DOI: 10.1074/jbc.M114.602581  0.361
2014 Frisk M, Koivumäki JT, Norseng PA, Maleckar MM, Sejersted OM, Louch WE. Variable t-tubule organization and Ca2+ homeostasis across the atria. American Journal of Physiology. Heart and Circulatory Physiology. 307: H609-20. PMID 24951751 DOI: 10.1152/ajpheart.00295.2014  0.362
2014 Boardman NT, Aronsen JM, Louch WE, Sjaastad I, Willoch F, Christensen G, Sejersted O, Aasum E. Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1018-24. PMID 24486508 DOI: 10.1152/ajpheart.00741.2013  0.448
2014 Hodne K, Wanichawan P, Hafver TL, Aronsen JM, Lunde IG, Lunde M, Kvaløy H, Tønnessen T, Sjaastad I, Louch WE, Sejersted OM, Carlson CR. Identification and Functional Role of Calpain Cleavage Site in Na+-Ca2+ Exchanger 1 (NCX1) Biophysical Journal. 106: 762a-763a. DOI: 10.1016/j.bpj.2013.11.4195  0.365
2013 Øyehaug L, Loose KØ, Jølle GF, Røe ÅT, Sjaastad I, Christensen G, Sejersted OM, Louch WE. Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity. Biophysical Journal. 104: 1685-97. PMID 23601316 DOI: 10.1016/j.bpj.2013.03.022  0.47
2013 Louch WE, Lyon AR. Mind the store: modulating Ca(2+) reuptake with a leaky sarcoplasmic reticulum. Cardiovascular Research. 98: 165-8. PMID 23524302 DOI: 10.1093/cvr/cvt069  0.43
2013 Stokke MK, Tovsrud N, Louch WE, Øyehaug L, Hougen K, Sejersted OM, Swift F, Sjaastad I. I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation. Cardiovascular Research. 98: 315-25. PMID 23417043 DOI: 10.1093/cvr/cvt037  0.476
2013 Louch WE, Hake J, Mørk HK, Hougen K, Skrbic B, Ursu D, Tønnessen T, Sjaastad I, Sejersted OM. Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units? Journal of Molecular and Cellular Cardiology. 58: 41-52. PMID 23376034 DOI: 10.1016/j.yjmcc.2013.01.014  0.498
2013 Røe ÅT, Aronsen JM, Frisk M, Sejersted OM, Sjaastad I, Louch WE. Compensated Cardiomyocyte Ca2+ Homeostasis in a Rat Model of Diastolic Heart Failure Biophysical Journal. 104: 603a. DOI: 10.1016/j.bpj.2012.11.3346  0.376
2012 Louch WE, Stokke MK, Sjaastad I, Christensen G, Sejersted OM. No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium. Physiology (Bethesda, Md.). 27: 308-23. PMID 23026754 DOI: 10.1152/physiol.00021.2012  0.464
2012 Li L, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sejersted OM, Smith NP. Sodium accumulation in SERCA knockout-induced heart failure. Biophysical Journal. 102: 2039-48. PMID 22824267 DOI: 10.1016/j.bpj.2012.03.045  0.39
2012 Louch WE, Vangheluwe P, Bito V, Raeymaekers L, Wuytack F, Sipido KR. Phospholamban ablation in hearts expressing the high affinity SERCA2b isoform normalizes global Ca²⁺ homeostasis but not Ca²⁺-dependent hypertrophic signaling. American Journal of Physiology. Heart and Circulatory Physiology. 302: H2574-82. PMID 22505640 DOI: 10.1152/ajpheart.01166.2011  0.498
2012 Swift F, Franzini-Armstrong C, Øyehaug L, Enger UH, Andersson KB, Christensen G, Sejersted OM, Louch WE. Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout. Proceedings of the National Academy of Sciences of the United States of America. 109: 3997-4001. PMID 22355118 DOI: 10.1073/pnas.1120172109  0.471
2012 Loose KO, Sadredini MN, Sejersted OM, Stokke MK, Louch WE. Ca2+ Wave Velocity in Cardiomyocytes is Regulated by Ryanodine Receptor Ca2+ Sensitivity and SR Ca2+ Content Biophysical Journal. 102: 99a-100a. DOI: 10.1016/j.bpj.2011.11.565  0.439
2011 Stokke MK, Briston SJ, Jølle GF, Manzoor I, Louch WE, Øyehaug L, Christensen G, Eisner DA, Trafford AW, Sejersted OM, Sjaastad I. Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content. Cardiovascular Research. 90: 503-12. PMID 21242164 DOI: 10.1093/Cvr/Cvr013  0.466
2011 Mørk HK, Richard S, Stokke MK, Sjaastad I, Andersson KB, Christensen G, Sejersted OM, Louch WE. SERCA2 Knockout Mice Exhibit Impaired Control of Ca2+ Current but not Ventricular Arrhythmias Biophysical Journal. 100: 574a. DOI: 10.1016/j.bpj.2010.12.3321  0.397
2011 Hake J, Louch WE, Haugen K, Sjaastad I, Sejersted OM, McCulloch A, Michailova A, Lines GT. A Stochastic Model of the Ryanodine Receptor Featuring Coupled Gating and Competitive Binding of Luminal and Cytosolic Ca2+ and Mg2+ Biophysical Journal. 100: 556a. DOI: 10.1016/J.Bpj.2010.12.3233  0.386
2011 Swift F, Franzini-Armstrong C, Enger UH, Andersson KB, Christensen G, Sejersted OM, Louch WE. Remodeling of the Sarcoplasmic Reticulum and T-Tubules in Cardiomyocytes Following Conditional SERCA2 Knockout Biophysical Journal. 100: 293a. DOI: 10.1016/j.bpj.2010.12.1804  0.385
2010 Louch WE, Hake J, Jølle GF, Mørk HK, Sjaastad I, Lines GT, Sejersted OM. Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes. Biophysical Journal. 99: 1377-86. PMID 20816049 DOI: 10.1016/j.bpj.2010.06.055  0.49
2010 Louch WE, Sejersted OM, Swift F. There goes the neighborhood: pathological alterations in T-tubule morphology and consequences for cardiomyocyte Ca2+ handling. Journal of Biomedicine & Biotechnology. 2010: 503906. PMID 20396394 DOI: 10.1155/2010/503906  0.394
2010 Stokke MK, Hougen K, Sjaastad I, Louch WE, Briston SJ, Enger UH, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW. Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes. Cardiovascular Research. 86: 63-71. PMID 20019150 DOI: 10.1093/Cvr/Cvp401  0.439
2010 Louch WE, Hougen K, Mørk HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM. Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout. The Journal of Physiology. 588: 465-78. PMID 20008467 DOI: 10.1113/jphysiol.2009.183517  0.499
2010 Louch WE, Mørk HK, Hougen K, Sjaastad I, Sejersted OM. Alterations in Ca2+ Sparks and T-Tubules Promote Slowed, Dyssynchronous Ca2+ Release in Failing Cardiomyocytes Biophysical Journal. 98: 105a-106a. DOI: 10.1016/j.bpj.2009.12.587  0.453
2010 Hake J, Jølle GF, Mørk HK, Sjaastad I, Sejersted OM, Louch WE, Lines GT. Control of Ca Release Synchrony by Action Potential Configuration in Murine Cardiomyocytes Biophysical Journal. 98: 296a. DOI: 10.1016/j.bpj.2009.12.1610  0.414
2009 Reuter H, Louch WE, Brette F, Sham JS, Sun H, Yang XR, Soeller C, Lakatta EG, Balijepalli RC. Commentaries on viewpoint: The cardiac contraction cycle: is Ca2+ going local? Counterpoint. Journal of Applied Physiology (Bethesda, Md. : 1985). 107: 1985-7; author reply. PMID 19952386 DOI: 10.1152/japplphysiol.01028.2009  0.445
2009 Andersson KB, Birkeland JA, Finsen AV, Louch WE, Sjaastad I, Wang Y, Chen J, Molkentin JD, Chien KR, Sejersted OM, Christensen G. Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. Journal of Molecular and Cellular Cardiology. 47: 180-7. PMID 19328205 DOI: 10.1016/J.Yjmcc.2009.03.013  0.501
2009 Mørk HK, Sjaastad I, Sejersted OM, Louch WE. Slowing of cardiomyocyte Ca2+ release and contraction during heart failure progression in postinfarction mice. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1069-79. PMID 19201998 DOI: 10.1152/ajpheart.01009.2008  0.502
2009 Stokke MK, Hougen K, Sjaastad I, Louch WE, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW. Ca2+ Wave Development in Ventricular Cardiomyocytes from Mice with Inducible Knockout of SERCA2 Biophysical Journal. 96: 275a. DOI: 10.1016/J.Bpj.2008.12.1361  0.464
2008 Swift F, Birkeland JA, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM. Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure. Cardiovascular Research. 78: 71-8. PMID 18203708 DOI: 10.1093/cvr/cvn013  0.356
2008 Swift F, Birkeland JAK, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM. Corrigendum to: Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase  2-isoform in heart failure Cardiovascular Research. 79: 352-352. DOI: 10.1093/cvr/cvn147  0.312
2007 Mørk HK, Sjaastad I, Sande JB, Periasamy M, Sejersted OM, Louch WE. Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure. Journal of Molecular and Cellular Cardiology. 43: 177-86. PMID 17574269 DOI: 10.1016/j.yjmcc.2007.05.004  0.53
2006 Vangheluwe P, Tjwa M, Van Den Bergh A, Louch WE, Beullens M, Dode L, Carmeliet P, Kranias E, Herijgers P, Sipido KR, Raeymaekers L, Wuytack F. A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span. Journal of Molecular and Cellular Cardiology. 41: 308-17. PMID 16814319 DOI: 10.1016/J.Yjmcc.2006.05.014  0.465
2006 Louch WE, Mørk HK, Sexton J, Strømme TA, Laake P, Sjaastad I, Sejersted OM. T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction. The Journal of Physiology. 574: 519-33. PMID 16709642 DOI: 10.1113/jphysiol.2006.107227  0.447
2006 Lines GT, Sande JB, Louch WE, Mørk HK, Grøttum P, Sejersted OM. Contribution of the Na+/Ca2+ exchanger to rapid Ca2+ release in cardiomyocytes. Biophysical Journal. 91: 779-92. PMID 16679359 DOI: 10.1529/biophysj.105.072447  0.46
2006 Louch WE, Mork HK, Sjaastad I, Sejersted OM. Increased nuclear Ca2+ transients in murine cardiomyocytes during congestive heart failure following myocardial infarction Journal of Molecular and Cellular Cardiology. 40: 948. DOI: 10.1016/j.yjmcc.2006.03.091  0.433
2005 Louch WE, Ferrier GR, Howlett SE. Attentuation of cardiac stunning by losartan in a cellular model of ischemia and reperfusion is accompanied by increased sarcoplasmic reticulum Ca2+ stores and prevention of cytosolic Ca2+ elevation. The Journal of Pharmacology and Experimental Therapeutics. 312: 238-47. PMID 15316090 DOI: 10.1124/Jpet.104.072769  0.603
2004 Louch WE, Bito V, Heinzel FR, Macianskiene R, Vanhaecke J, Flameng W, Mubagwa K, Sipido KR. Reduced synchrony of Ca2+ release with loss of T-tubules-a comparison to Ca2+ release in human failing cardiomyocytes. Cardiovascular Research. 62: 63-73. PMID 15023553 DOI: 10.1016/j.cardiores.2003.12.031  0.449
2003 Vangheluwe P, Louch WE, Ver Heyen M, Sipido K, Raeymaekers L, Wuytack F. Ca2+ transport ATPase isoforms SERCA2a and SERCA2b are targeted to the same sites in the murine heart. Cell Calcium. 34: 457-64. PMID 14572804  0.307
2003 Au A, Louch WE, Ferrier GR, Howlett SE. L-Arginine ameliorates effects of ischemia and reperfusion in isolated cardiac myocytes. European Journal of Pharmacology. 476: 45-54. PMID 12969748 DOI: 10.1016/S0014-2999(03)02175-7  0.558
2002 Louch WE, Ferrier GR, Howlett SE. Changes in excitation-contraction coupling in an isolated ventricular myocyte model of cardiac stunning. American Journal of Physiology. Heart and Circulatory Physiology. 283: H800-10. PMID 12124230 DOI: 10.1152/Ajpheart.00020.2002  0.619
2000 Louch WE, Ferrier GR, Howlett SE. Losartan improves recovery of contraction and inhibits transient inward current in a cellular model of cardiac ischemia and reperfusion. The Journal of Pharmacology and Experimental Therapeutics. 295: 697-704. PMID 11046108  0.497
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