David J. Granville, Ph.D. - Publications

Affiliations: 
2001 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Pathology, Rehabilitation and Therapy, Cell Biology

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gapud EJ, Trejo-Zambrano MI, Gomez-Banuelos E, Tiniakou E, Antiochos B, Granville DJ, Andrade F, Casciola-Rosen L, Rosen A. Granzyme B Induces IRF-3 Phosphorylation through a Perforin-Independent Proteolysis-Dependent Signaling Cascade without Inducing Cell Death. Journal of Immunology (Baltimore, Md. : 1950). PMID 33288544 DOI: 10.4049/jimmunol.2000546  0.327
2020 Sellers SL, Hensey M, Cartlidge TRG, Turner CT, Lau K, Lai A, Salcudean H, Sathananthan J, McManus BM, Granville DJ, Payne GW, Pibarot P, Webb JG, Newby DE, Blanke P, et al. Tricuspid Valve-in-Valve and Bioprosthetic Surgical Tricuspid and Pulmonic Valve Degeneration: Lessons From Imaging and Histopathology. Jacc. Cardiovascular Imaging. PMID 32739371 DOI: 10.1016/J.Jcmg.2020.06.008  0.429
2020 Turner CT, Zeglinski MR, Richardson KC, Santacruz S, Hiroyasu S, Wang C, Zhao H, Shen Y, Sehmi R, Lima H, Gauvreau GM, Granville DJ. GRANZYME B CONTRIBUTES TO BARRIER DYSFUNCTION IN OXAZOLONE-INDUCED SKIN INFLAMMATION THROUGH E-CADHERIN AND FILAGGRIN CLEAVAGE. The Journal of Investigative Dermatology. PMID 32504614 DOI: 10.1016/J.Jid.2020.05.095  0.331
2019 Turner CT, Hiroyasu S, Granville DJ. Granzyme B as a Therapeutic Target for Wound Healing. Expert Opinion On Therapeutic Targets. PMID 31461387 DOI: 10.1080/14728222.2019.1661380  0.311
2019 Hanson PJ, Hossain AR, Qiu Y, Zhang HM, Zhao G, Li C, Lin V, Sulaimon S, Vlok M, Fung G, Chen VH, Jan E, McManus BM, Granville DJ, Yang D. Cleavage and Sub-Cellular Redistribution of Nuclear Pore Protein 98 by Coxsackievirus B3 Protease 2A Impairs Cardioprotection. Frontiers in Cellular and Infection Microbiology. 9: 265. PMID 31396490 DOI: 10.3389/Fcimb.2019.00265  0.546
2019 Cait J, Hughes MR, Zeglinski MR, Chan AW, Osterhof S, Scott RW, Canals Hernaez D, Cait A, Vogl AW, Bernatchez P, Underhill TM, Granville DJ, Murphy TH, Roskelley CD, McNagny KM. Podocalyxin is required for maintaining blood-brain barrier function during acute inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30787191 DOI: 10.1073/Pnas.1814766116  0.306
2019 Sellers S, Cartlidge T, Hensey M, Turner C, Lai A, Lau K, Sathananthan J, Blanke P, Granville D, McManus B, Webb J, Newby D, Dweck M, Leipsic J. TCT-96 Tricuspid Valve-in-Valve and Bioprosthetic Surgical Tricuspid and Pulmonic Valve Degeneration: Lessons From Imaging and Histopathology Journal of the American College of Cardiology. 74. DOI: 10.1016/J.Jacc.2019.08.139  0.43
2018 Haage A, Goodwin K, Whitewood A, Camp D, Bogutz A, Turner CT, Granville DJ, Lefebvre L, Plotnikov S, Goult BT, Tanentzapf G. Talin Autoinhibition Regulates Cell-ECM Adhesion Dynamics and Wound Healing In Vivo. Cell Reports. 25: 2401-2416.e5. PMID 30485809 DOI: 10.1016/J.Celrep.2018.10.098  0.32
2018 Turner CT, Zeglinski MR, Richardson KC, Zhao H, Shen Y, Papp A, Bird PI, Granville DJ. Granzyme K Expressed by Classically Activated Macrophages Contributes to Inflammation and Impaired Remodeling. The Journal of Investigative Dermatology. PMID 30395844 DOI: 10.1016/J.Jid.2018.09.031  0.3
2018 Russo V, Klein T, Lim DJ, Solis N, Machado Y, Hiroyasu S, Nabai L, Shen Y, Zeglinski MR, Zhao H, Oram CP, Lennox PA, Van Laeken N, Carr NJ, Crawford RI, ... ... Granville DJ, et al. Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction. Scientific Reports. 8: 9690. PMID 29946113 DOI: 10.1038/S41598-018-28070-0  0.303
2018 Shen Y, Zeglinski MR, Turner CT, Raithatha SA, Wu Z, Russo V, Oram C, Hiroyasu S, Nabai L, Zhao H, Bozin T, Westendorf K, Kopko I, Huang R, Arns S, ... ... Granville DJ, et al. Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing. Experimental & Molecular Medicine. 50: 68. PMID 29849046 DOI: 10.1038/S12276-018-0095-0  0.315
2017 Turner CT, Lim D, Granville DJ. Granzyme B in skin inflammation and disease. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29247692 DOI: 10.1016/J.Matbio.2017.12.005  0.329
2017 Shen Y, Russo V, Zeglinski MR, Sellers SL, Wu Z, Oram C, Santacruz S, Merkulova Y, Turner C, Tauh K, Zhao H, Bozin T, Bohunek L, Zeng H, Seidman MA, ... ... Granville DJ, et al. Recombinant Decorin Fusion Protein Attenuates Murine Abdominal Aortic Aneurysm Formation and Rupture. Scientific Reports. 7: 15857. PMID 29158532 DOI: 10.1038/S41598-017-16194-8  0.47
2017 Arias M, Martínez-Lostao L, Santiago L, Ferrandez A, Granville DJ, Pardo J. The Untold Story of Granzymes in Oncoimmunology: Novel Opportunities with Old Acquaintances. Trends in Cancer. 3: 407-422. PMID 28718416 DOI: 10.1016/J.Trecan.2017.04.001  0.338
2016 Merkulova Y, Shen Y, Parkinson LG, Raithatha SA, Zhao H, Westendorf K, Sharma M, Bleackley RC, Granville DJ. Granzyme B inhibits keratinocyte migration by disrupting epidermal growth factor receptor (EGFR)-mediated signalling. Biological Chemistry. PMID 27060743 DOI: 10.1515/Hsz-2016-0129  0.33
2016 Sharma M, Merkulova Y, Raithatha S, Parkinson LG, Shen Y, Cooper D, Granville DJ. Extracellular Granzyme K Mediates Endothelial Activation Through the Cleavage of Protease Activated Receptor-1 (PAR-1). The Febs Journal. PMID 26936634 DOI: 10.1111/Febs.13699  0.398
2015 Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha SA, Parkinson LG, Zhao H, Westendorf K, Bohunek L, Bozin T, Hsu I, Ang LS, Williams SJ, Bleackley RC, Eriksson JE, ... ... Granville DJ, et al. Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis. The American Journal of Pathology. PMID 26610869 DOI: 10.1016/J.Ajpath.2015.09.010  0.517
2015 Hanson PJ, Ye X, Qiu Y, Zhang HM, Hemida MG, Wang F, Lim T, Gu A, Cho B, Kim H, Fung G, Granville DJ, Yang D. Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genes. Cell Death and Differentiation. PMID 26586572 DOI: 10.1038/Cdd.2015.145  0.366
2015 Sharma A, Sellers S, Stefanovic N, Leung C, Tan SM, Huet O, Granville DJ, Cooper ME, de Haan JB, Bernatchez P. Direct eNOS activation provides atheroprotection in diabetes-accelerated atherosclerosis. Diabetes. PMID 26116699 DOI: 10.2337/Db15-0472  0.302
2015 Parkinson LG, Toro A, Zhao H, Brown K, Tebbutt SJ, Granville DJ. Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation. Aging Cell. 14: 67-77. PMID 25495009 DOI: 10.1111/Acel.12298  0.326
2014 Hendel A, Hsu I, Granville DJ. Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 716-25. PMID 24791744 DOI: 10.1038/Labinvest.2014.62  0.304
2014 Marchant DJ, Bellac CL, Moraes TJ, Wadsworth SJ, Dufour A, Butler GS, Bilawchuk LM, Hendry RG, Robertson AG, Cheung CT, Ng J, Ang L, Luo Z, Heilbron K, Norris MJ, ... ... Granville DJ, et al. A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity. Nature Medicine. 20: 493-502. PMID 24784232 DOI: 10.1038/Nm.3508  0.478
2013 Hiebert PR, Boivin WA, Zhao H, McManus BM, Granville DJ. Perforin and granzyme B have separate and distinct roles during atherosclerotic plaque development in apolipoprotein E knockout mice. Plos One. 8: e78939. PMID 24205352 DOI: 10.1371/Journal.Pone.0078939  0.511
2013 Hirota JA, Hiebert PR, Gold M, Wu D, Graydon C, Smith JA, Ask K, McNagny K, Granville DJ, Knight DA. Granzyme B deficiency exacerbates lung inflammation in mice after acute lung injury. American Journal of Respiratory Cell and Molecular Biology. 49: 453-62. PMID 23642129 DOI: 10.1165/Rcmb.2012-0512Oc  0.301
2013 Kim WD, Chi HS, Choe KH, Oh YM, Lee SD, Kim KR, Yoo KH, Ngan DA, Elliott WM, Granville DJ, Sin DD, Hogg JC. A possible role for CD8+ and non-CD8+ cell granzyme B in early small airway wall remodelling in centrilobular emphysema. Respirology (Carlton, Vic.). 18: 688-96. PMID 23421932 DOI: 10.1111/Resp.12069  0.351
2013 Hendel A, Granville DJ. Granzyme B cleavage of fibronectin disrupts endothelial cell adhesion, migration and capillary tube formation. Matrix Biology : Journal of the International Society For Matrix Biology. 32: 14-22. PMID 23228447 DOI: 10.1016/J.Matbio.2012.11.013  0.362
2012 Hiebert PR, Granville DJ. Granzyme B in injury, inflammation, and repair. Trends in Molecular Medicine. 18: 732-41. PMID 23099058 DOI: 10.1016/J.Molmed.2012.09.009  0.313
2012 Boivin WA, Shackleford M, Vanden Hoek A, Zhao H, Hackett TL, Knight DA, Granville DJ. Granzyme B cleaves decorin, biglycan and soluble betaglycan, releasing active transforming growth factor-β1. Plos One. 7: e33163. PMID 22479366 DOI: 10.1371/Journal.Pone.0033163  0.376
2012 Marchant DJ, Boyd JH, Lin DC, Granville DJ, Garmaroudi FS, McManus BM. Inflammation in myocardial diseases. Circulation Research. 110: 126-44. PMID 22223210 DOI: 10.1161/Circresaha.111.243170  0.475
2012 Hendel A, Cooper D, Abraham T, Zhao H, Allard MF, Granville DJ. Proteinase inhibitor 9 is reduced in human atherosclerotic lesion development. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 21: 28-38. PMID 21296596 DOI: 10.1016/J.Carpath.2010.12.002  0.398
2011 Ang LS, Boivin WA, Williams SJ, Zhao H, Abraham T, Carmine-Simmen K, McManus BM, Bleackley RC, Granville DJ. Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm. Cell Death & Disease. 2: e209. PMID 21900960 DOI: 10.1038/Cddis.2011.88  0.537
2011 Cooper DM, Pechkovsky DV, Hackett TL, Knight DA, Granville DJ. Granzyme K activates protease-activated receptor-1. Plos One. 6: e21484. PMID 21760880 DOI: 10.1371/Journal.Pone.0021484  0.331
2010 Granville DJ. Granzymes in disease: bench to bedside. Cell Death and Differentiation. 17: 565-6. PMID 20228822 DOI: 10.1038/Cdd.2009.218  0.45
2010 Hendel A, Hiebert PR, Boivin WA, Williams SJ, Granville DJ. Granzymes in age-related cardiovascular and pulmonary diseases. Cell Death and Differentiation. 17: 596-606. PMID 20139894 DOI: 10.1038/Cdd.2010.5  0.336
2010 Chamberlain CM, Ang LS, Boivin WA, Cooper DM, Williams SJ, Zhao H, Hendel A, Folkesson M, Swedenborg J, Allard MF, McManus BM, Granville DJ. Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm. The American Journal of Pathology. 176: 1038-49. PMID 20035050 DOI: 10.2353/Ajpath.2010.090700  0.499
2009 Boivin WA, Cooper DM, Hiebert PR, Granville DJ. Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 1195-220. PMID 19770840 DOI: 10.1038/Labinvest.2009.91  0.395
2009 Ngan DA, Vickerman SV, Granville DJ, Man SF, Sin DD. The possible role of granzyme B in the pathogenesis of chronic obstructive pulmonary disease. Therapeutic Advances in Respiratory Disease. 3: 113-29. PMID 19638369 DOI: 10.1177/1753465809341965  0.318
2009 Cooper DM, Granville DJ, Lowenberger C. The insect caspases. Apoptosis : An International Journal On Programmed Cell Death. 14: 247-56. PMID 19212814 DOI: 10.1007/S10495-009-0322-1  0.439
2009 Ghosh S, Khazaei M, Moien-Afshari F, Ang LS, Granville DJ, Verchere CB, Dunn SR, McCue P, Mizisin A, Sharma K, Laher I. Moderate exercise attenuates caspase-3 activity, oxidative stress, and inhibits progression of diabetic renal disease in db/db mice. American Journal of Physiology. Renal Physiology. 296: F700-8. PMID 19144689 DOI: 10.1152/Ajprenal.90548.2008  0.339
2008 Hunter AL, Kerjner A, Mueller KJ, McManus BM, Granville DJ. Cytochrome p450 2C enzymes contribute to peritransplant ischemic injury and cardiac allograft vasculopathy. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 8: 1631-8. PMID 18557730 DOI: 10.1111/J.1600-6143.2008.02296.X  0.506
2007 Boivin WA, Granville DJ. Detection and quantification of apoptosis in the vasculature. Methods in Molecular Medicine. 139: 181-95. PMID 18287672 DOI: 10.1007/978-1-59745-571-8_11  0.478
2007 Hunter AL, Zhang J, Chen SC, Si X, Wong B, Ekhterae D, Luo H, Granville DJ. Apoptosis repressor with caspase recruitment domain (ARC) inhibits myogenic differentiation. Febs Letters. 581: 879-84. PMID 17292893 DOI: 10.1016/J.Febslet.2007.01.050  0.382
2007 Hunter A, Kerjner A, Mueller K, McManus B, Granville D. 149: Cytochrome P450 (CYP) 2C contributes to cardiac allograft vasculopathy The Journal of Heart and Lung Transplantation. 26: S113. DOI: 10.1016/J.Healun.2006.11.165  0.475
2006 Rahmani M, Cruz RP, Granville DJ, McManus BM. Allograft vasculopathy versus atherosclerosis. Circulation Research. 99: 801-15. PMID 17038650 DOI: 10.1161/01.Res.0000246086.93555.F3  0.513
2006 Cruz RP, Zhao H, Choy JC, McManus BM, Granville DJ. Granzyme B in age-associated disorders: Unique and exciting characteristics discovered in a double knockout model Vascular Pharmacology. 45: e91. DOI: 10.1016/J.Vph.2006.08.257  0.434
2006 Cruz RP, Zhao H, McManus BM, Choy J, Granville DJ. Granzyme B is expressed in macrophage foam cells and plays a key role in atherosclerosis Vascular Pharmacology. 45: 191-192. DOI: 10.1016/J.Vph.2006.08.047  0.496
2005 Hunter AL, Choy JC, Granville DJ. Detection of apoptosis in cardiovascular diseases. Methods in Molecular Medicine. 112: 277-89. PMID 16010024 DOI: 10.1385/1-59259-879-X:277  0.437
2005 Choy JC, Cruz RP, Kerjner A, Geisbrecht J, Sawchuk T, Fraser SA, Hudig D, Bleackley RC, Jirik FR, McManus BM, Granville DJ. Granzyme B induces endothelial cell apoptosis and contributes to the development of transplant vascular disease. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 494-9. PMID 15707403 DOI: 10.1111/J.1600-6143.2004.00710.X  0.587
2004 Hunter AL, Cruz RP, Cheyne BM, McManus BM, Granville DJ. Cytochrome p450 enzymes and cardiovascular disease. Canadian Journal of Physiology and Pharmacology. 82: 1053-60. PMID 15644946 DOI: 10.1139/Y04-118  0.477
2004 Choy JC, Hung VH, Hunter AL, Cheung PK, Motyka B, Goping IS, Sawchuk T, Bleackley RC, Podor TJ, McManus BM, Granville DJ. Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 2245-50. PMID 15472125 DOI: 10.1161/01.Atv.0000147162.51930.B7  0.596
2004 Choy JC, Kerjner A, Wong BW, McManus BM, Granville DJ. Perforin mediates endothelial cell death and resultant transplant vascular disease in cardiac allografts. The American Journal of Pathology. 165: 127-33. PMID 15215168 DOI: 10.1016/S0002-9440(10)63281-6  0.51
2004 Choy JC, Kerjner A, Wong BW, McManus BM, Granville DJ. THE ROLE OF PERFORIN IN TRANSPLANT VASCULAR DISEASE Cardiovascular Pathology. 13: 136. DOI: 10.1016/J.Carpath.2004.03.410  0.466
2004 Cruz RP, Rezai N, Walinski H, Luo Z, Triche T, McManus BM, Granville DJ. MITRAL VALVE DISEASE: A GENOMIC COMPARISON OF VALVULAR INTERSTITIAL CELLS FROM NORMAL, FLOPPY AND RHEUMATIC VALVES Cardiovascular Pathology. 13: 32. DOI: 10.1016/J.Carpath.2004.03.089  0.45
2003 Choy JC, Podor TJ, Yanagawa B, Lai JC, Granville DJ, Walker DC, McManus BM. The regulation and consequences of immune-mediated cell death in atheromatous diseases. Cardiovascular Toxicology. 3: 269-82. PMID 14555792 DOI: 10.1385/Ct:3:3:269  0.641
2003 Carthy CM, Yanagawa B, Luo H, Granville DJ, Yang D, Cheung P, Cheung C, Esfandiarei M, Rudin CM, Thompson CB, Hunt DW, McManus BM. Bcl-2 and Bcl-xL overexpression inhibits cytochrome c release, activation of multiple caspases, and virus release following coxsackievirus B3 infection. Virology. 313: 147-57. PMID 12951029 DOI: 10.1016/S0042-6822(03)00242-3  0.792
2003 Li R, Bounds DJ, Granville D, Ip SH, Jiang H, Margaron P, Hunt DWC. Rapid induction of apoptosis in human keratinocytes with the photosensitizer QLT0074 via a direct mitochondrial action Apoptosis. 8: 269-275. PMID 12766487 DOI: 10.1023/A:1023624922787  0.483
2003 Choy JC, McDonald PC, Suarez AC, Hung VH, Wilson JE, McManus BM, Granville DJ. Granzyme B in atherosclerosis and transplant vascular disease: association with cell death and atherosclerotic disease severity. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 16: 460-70. PMID 12748253 DOI: 10.1097/01.Mp.0000067424.12280.Bc  0.555
2003 Loucks EB, Godin DV, Walley KR, McManus BM, Rahimian R, Granville DJ, Hong JM, Aktary FM, Qayumi AK. Role of platelet activating factor in cardiac dysfunction, apoptosis and nitric oxide synthase mRNA expression in the ischemic-reperfused rabbit heart. The Canadian Journal of Cardiology. 19: 267-74. PMID 12677282  0.431
2003 Choy J, Hung V, Myers J, Motyka B, Goping I, Sawchuck T, Bleackley R, McManus B, Granville D. Granzyme B, a cytotoxic immune protease, induces apoptosis of smooth muscle cells in the absence of perforin The Journal of Heart and Lung Transplantation. 22: S155. DOI: 10.1016/S1053-2498(02)00945-2  0.504
2002 Granville DJ, Gottlieb RA. Mitochondria: regulators of cell death and survival. Thescientificworldjournal. 2: 1569-78. PMID 12806142 DOI: 10.1100/tsw.2002.809  0.357
2002 Jiang H, Granville DJ, North JR, Richter AM, Hunt DW. Selective action of the photosensitizer QLT0074 on activated human T lymphocytes. Photochemistry and Photobiology. 76: 224-31. PMID 12194221 DOI: 10.1562/0031-8655(2002)076<0224:Saotpq>2.0.Co;2  0.363
2001 Miller LW, Granville DJ, Narula J, McManus BM. Apoptosis in cardiac transplant rejection. Cardiology Clinics. 19: 141-54. PMID 11787808 DOI: 10.1016/S0733-8651(05)70200-9  0.569
2001 Granville DJ, Ruehlmann DO, Choy JC, Cassidy BA, Hunt DW, van Breemen C, McManus BM. Bcl-2 increases emptying of endoplasmic reticulum Ca2+ stores during photodynamic therapy-induced apoptosis. Cell Calcium. 30: 343-50. PMID 11733941 DOI: 10.1054/Ceca.2001.0243  0.433
2001 Granville DJ, Jiang H, McManus BM, Hunt DW. Fas ligand and TRAIL augment the effect of photodynamic therapy on the induction of apoptosis in JURKAT cells. International Immunopharmacology. 1: 1831-40. PMID 11562074 DOI: 10.1016/S1567-5769(01)00107-2  0.565
2001 Choy JC, Granville DJ, Hunt DW, McManus BM. Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis. Journal of Molecular and Cellular Cardiology. 33: 1673-90. PMID 11549346 DOI: 10.1006/Jmcc.2001.1419  0.571
2001 Matroule JY, Carthy CM, Granville DJ, Jolois O, Hunt DW, Piette J. Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization. Oncogene. 20: 4070-84. PMID 11494135 DOI: 10.1038/Sj.Onc.1204546  0.776
2001 Granville DJ, Cassidy BA, Ruehlmann DO, Choy JC, Brenner C, Kroemer G, van Breemen C, Margaron P, Hunt DW, McManus BM. Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis. The American Journal of Pathology. 159: 305-11. PMID 11438477 DOI: 10.1016/S0002-9440(10)61696-3  0.625
2001 Granville DJ, McManus BM, Hunt DW. Photodynamic therapy: shedding light on the biochemical pathways regulating porphyrin-mediated cell death. Histology and Histopathology. 16: 309-17. PMID 11193207 DOI: 10.14670/Hh-16.309  0.512
2001 McGarrity TJ, Peiffer LP, Granville DJ, Carthy CM, Levy JG, Khandelwal M, Hunt DW. Apoptosis associated with esophageal adenocarcinoma: influence of photodynamic therapy. Cancer Letters. 163: 33-41. PMID 11163106 DOI: 10.1016/S0304-3835(00)00663-7  0.753
2000 Granville DJ, Carthy CM, Jiang H, Levy JG, McManus BM, Matroule JY, Piette J, Hunt DW. Nuclear factor-kappaB activation by the photochemotherapeutic agent verteporfin. Blood. 95: 256-62. PMID 10607710  0.78
2000 Granville DJ, Carthy CM, Jiang H, Levy JG, McManus BM, Matroule J, Piette J, Hunt DWC. Nuclear factor-κB activation by the photochemotherapeutic agent verteporfin Blood. 95: 256-262. DOI: 10.1182/Blood.V95.1.256.001K29_256_262  0.612
1999 Dong C, Granville DJ, Tuffnel CE, Kenyon J, English D, Wilson JE, McManus BM. Bax and apoptosis in acute and chronic rejection of rat cardiac allografts. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 1643-53. PMID 10616213  0.53
1999 Granville DJ, Shaw JR, Leong S, Carthy CM, Margaron P, Hunt DW, McManus BM. Release of cytochrome c, Bax migration, Bid cleavage, and activation of caspases 2, 3, 6, 7, 8, and 9 during endothelial cell apoptosis. The American Journal of Pathology. 155: 1021-5. PMID 10514382 DOI: 10.1016/S0002-9440(10)65202-9  0.797
1999 Carthy CM, Granville DJ, Jiang H, Levy JG, Rudin CM, Thompson CB, McManus BM, Hunt DW. Early release of mitochondrial cytochrome c and expression of mitochondrial epitope 7A6 with a porphyrin-derived photosensitizer: Bcl-2 and Bcl-xL overexpression do not prevent early mitochondrial events but still depress caspase activity. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 953-65. PMID 10462033  0.778
1999 Granville DJ, Jiang H, An MT, Levy JG, McManus BM, Hunt DW. Bcl-2 overexpression blocks caspase activation and downstream apoptotic events instigated by photodynamic therapy. British Journal of Cancer. 79: 95-100. PMID 10408699 DOI: 10.1038/Sj.Bjc.6690017  0.63
1999 Jiang H, Granville DJ, McManus BM, Levy JG, Hunt DW. Selective depletion of a thymocyte subset in vitro with an immunomodulatory photosensitizer. Clinical Immunology (Orlando, Fla.). 91: 178-87. PMID 10227810 DOI: 10.1006/Clim.1999.4695  0.494
1999 Koglin J, Granville DJ, Glysing-Jensen T, Mudgett JS, Carthy CM, McManus BM, Russell ME. Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis. Circulation. 99: 836-42. PMID 9989972 DOI: 10.1161/01.Cir.99.6.836  0.752
1999 McDonald PC, Wong D, Granville DJ, McManus BM. Emerging roles of endothelial cells and smooth muscle cells in transplant vascular disease Transplantation Reviews. 13: 109-127. DOI: 10.1016/S0955-470X(99)80070-6  0.546
1998 Granville DJ, Carthy CM, Yang D, Hunt DW, McManus BM. Interaction of viral proteins with host cell death machinery. Cell Death and Differentiation. 5: 653-9. PMID 10200520 DOI: 10.1038/Sj.Cdd.4400388  0.763
1998 Granville DJ, Carthy CM, Jiang H, Shore GC, McManus BM, Hunt DW. Rapid cytochrome c release, activation of caspases 3, 6, 7 and 8 followed by Bap31 cleavage in HeLa cells treated with photodynamic therapy. Febs Letters. 437: 5-10. PMID 9804161 DOI: 10.1016/S0014-5793(98)01193-4  0.796
1998 Carthy CM, Granville DJ, Watson KA, Anderson DR, Wilson JE, Yang D, Hunt DW, McManus BM. Caspase activation and specific cleavage of substrates after coxsackievirus B3-induced cytopathic effect in HeLa cells. Journal of Virology. 72: 7669-75. PMID 9696873 DOI: 10.1128/Jvi.72.9.7669-7675.1998  0.792
1998 Granville DJ, Jiang H, An MT, Levy JG, McManus BM, Hunt DW. Overexpression of Bcl-X(L) prevents caspase-3-mediated activation of DNA fragmentation factor (DFF) produced by treatment with the photochemotherapeutic agent BPD-MA. Febs Letters. 422: 151-4. PMID 9489995 DOI: 10.1016/S0014-5793(97)01616-5  0.571
1998 Granville DJ, Levy JG, Hunt DWC. Photodynamic Treatment with Benzoporphyrin Derivative Monoacid Ring A Produces Protein Tyrosine Phosphorylation Events and DNA Fragmentation in Murine P815 Cells Photochemistry and Photobiology. 67: 358-362. DOI: 10.1111/J.1751-1097.1998.Tb05210.X  0.34
1997 Granville DJ, Levy JG, Hunt DW. Photodynamic therapy induces caspase-3 activation in HL-60 cells. Cell Death and Differentiation. 4: 623-8. PMID 14555976 DOI: 10.1038/Sj.Cdd.4400286  0.469
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