Bradford C. Berk - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Molecular Biology, Cell Biology

269 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Meghwani H, Berk BC. MST1 Kinase-Cx43-YAP/TAZ Pathway Mediates Disturbed Flow Endothelial Dysfunction. Circulation Research. 131: 765-767. PMID 36252051 DOI: 10.1161/CIRCRESAHA.122.321921  0.339
2020 Xue C, Senchanthisai S, Sowden M, Pang J, White J, Berk BC. Endothelial-to-Mesenchymal Transition and Inflammation Play Key Roles in Cyclophilin A-Induced Pulmonary Arterial Hypertension. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11914. PMID 32829656 DOI: 10.1161/Hypertensionaha.119.14013  0.364
2020 Wines-Samuelson M, Chowdhury S, Berk BC. Nck1 is a critical adaptor between proatherogenic blood flow, inflammation, and atherosclerosis. The Journal of Clinical Investigation. PMID 32657777 DOI: 10.1172/Jci138536  0.409
2019 Plekhanova O, Parfyonova Y, Beloglazova I, Berk BC, Tkachuk V. Oligonucleotide Microarrays Identified Potential Regulatory Genes Related to Early Outward Arterial Remodeling Induced by Tissue Plasminogen Activator. Frontiers in Physiology. 10: 493. PMID 31114508 DOI: 10.3389/Fphys.2019.00493  0.368
2019 Carmo LSD, Berk BC, Harrison DG. NOX5 as a therapeutic target in cerebral ischemic injury. The Journal of Clinical Investigation. 130. PMID 30882364 DOI: 10.1172/Jci127682  0.301
2018 Xue C, Sowden MP, Berk BC. Extracellular and Intracellular Cyclophilin A, Native and Post-Translationally Modified, Show Diverse and Specific Pathological Roles in Diseases. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29599134 DOI: 10.1161/Atvbaha.117.310661  0.322
2017 Li Y, Ren M, Wang X, Cui X, Zhao H, Zhao C, Zhou J, Guo Y, Hu Y, Yan C, Berk B, Wang J. Glutaredoxin 1 mediates the protective effect of steady laminar flow on endothelial cells against oxidative stress-induced apoptosis via inhibiting Bim. Scientific Reports. 7: 15539. PMID 29138498 DOI: 10.1038/S41598-017-15672-3  0.462
2017 Xue C, Sowden M, Berk BC. Extracellular Cyclophilin A, Especially Acetylated, Causes Pulmonary Hypertension by Stimulating Endothelial Apoptosis, Redox Stress, and Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28450293 DOI: 10.1161/Atvbaha.117.309212  0.348
2016 Majumder S, Zhu G, Xu X, Senchanthisai S, Jiang D, Liu H, Xue C, Wang X, Coia H, Cui Z, Smolock EM, Libby RT, Berk BC, Pang J. G-Protein-Coupled Receptor-2-Interacting Protein-1 Controls Stalk Cell Fate by Inhibiting Delta-like 4-Notch1 Signaling. Cell Reports. 17: 2532-2541. PMID 27926858 DOI: 10.1016/J.Celrep.2016.11.017  0.415
2016 Perrucci GL, Straino S, Corlianò M, Scopece A, Napolitano M, Berk BC, Lombardi F, Pompilio G, Capogrossi MC, Nigro P. Cyclophilin A modulates bone marrow-derived CD117(+) cells and enhances ischemia-induced angiogenesis via the SDF-1/CXCR4 axis. International Journal of Cardiology. 212: 324-35. PMID 27057951 DOI: 10.1016/J.Ijcard.2016.03.082  0.334
2016 Heo KS, Berk BC, Abe JI. Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events. Antioxidants & Redox Signaling. PMID 26714841 DOI: 10.1089/Ars.2015.6556  0.383
2015 Shi X, O'Neill MM, MacDonnell S, Brookes PS, Yan C, Berk BC. The RSK Inhibitor BIX02565 Limits Cardiac Ischemia/Reperfusion Injury. Journal of Cardiovascular Pharmacology and Therapeutics. PMID 26130615 DOI: 10.1177/1074248415591700  0.338
2015 Simons M, Alitalo K, Annex BH, Augustin HG, Beam C, Berk BC, Byzova T, Carmeliet P, Chilian W, Cooke JP, Davis GE, Eichmann A, Iruela-Arispe ML, Keshet E, Sinusas AJ, et al. State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association. Circulation Research. 116: e99-132. PMID 25931450 DOI: 10.1161/Res.0000000000000054  0.402
2014 Abe J, Berk BC. Novel mechanisms of endothelial mechanotransduction. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2378-86. PMID 25301843 DOI: 10.1161/Atvbaha.114.303428  0.481
2014 Sheu TJ, Zhou W, Fan J, Zhou H, Zuscik MJ, Xie C, Yin G, Berk BC. Decreased BMP2 signal in GIT1 knockout mice slows bone healing. Molecular and Cellular Biochemistry. 397: 67-74. PMID 25138700 DOI: 10.1007/S11010-014-2173-5  0.373
2014 Yin G, Sheu TJ, Menon P, Pang J, Ho HC, Shi S, Xie C, Smolock E, Yan C, Zuscik MJ, Berk BC. Impaired angiogenesis during fracture healing in GPCR kinase 2 interacting protein-1 (GIT1) knock out mice. Plos One. 9: e89127. PMID 24586541 DOI: 10.1371/Journal.Pone.0089127  0.762
2014 Spindel ON, Burke RM, Yan C, Berk BC. Thioredoxin-interacting protein is a biomechanical regulator of Src activity: key role in endothelial cell stress fiber formation. Circulation Research. 114: 1125-32. PMID 24515523 DOI: 10.1161/Circresaha.114.301315  0.794
2014 Wang L, Soe NN, Sowden M, Xu Y, Modjeski K, Baskaran P, Kim Y, Smolock EM, Morrell CN, Berk BC. Cyclophilin A is an important mediator of platelet function by regulating integrin αIIbβ3 bidirectional signalling. Thrombosis and Haemostasis. 111: 873-82. PMID 24429998 DOI: 10.1160/Th13-09-0738  0.346
2014 Soe NN, Sowden M, Baskaran P, Kim Y, Nigro P, Smolock EM, Berk BC. Acetylation of cyclophilin A is required for its secretion and vascular cell activation. Cardiovascular Research. 101: 444-53. PMID 24293519 DOI: 10.1093/Cvr/Cvt268  0.446
2014 Majumder S, Sowden MP, Gerber SA, Thomas T, Christie CK, Mohan A, Yin G, Lord EM, Berk BC, Pang J. G-protein-coupled receptor-2-interacting protein-1 is required for endothelial cell directional migration and tumor angiogenesis via cortactin-dependent lamellipodia formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 419-26. PMID 24265417 DOI: 10.1161/Atvbaha.113.302689  0.337
2013 Soe NN, Sowden M, Baskaran P, Smolock EM, Kim Y, Nigro P, Berk BC. Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 2147-53. PMID 23846495 DOI: 10.1161/Atvbaha.113.301894  0.431
2013 Abe J, Berk BC. Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis. Circulation. 128: 579-82. PMID 23838164 DOI: 10.1161/Circulationaha.113.004390  0.416
2013 Abe J, Berk BC. Cezanne paints inflammation by regulating ubiquitination. Circulation Research. 112: 1526-8. PMID 23743222 DOI: 10.1161/Circresaha.113.301518  0.384
2013 Pang J, Xu X, Wang X, Majumder S, Wang J, Korshunov VA, Berk BC. G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migration. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 999-1005. PMID 23430614 DOI: 10.1161/Atvbaha.112.300966  0.49
2013 Park SY, Shi X, Pang J, Yan C, Berk BC. Thioredoxin-interacting protein mediates sustained VEGFR2 signaling in endothelial cells required for angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 737-43. PMID 23393387 DOI: 10.1161/Atvbaha.112.300386  0.442
2012 Smolock EM, Korshunov VA, Glazko G, Qiu X, Gerloff J, Berk BC. Ribosomal protein L17, RpL17, is an inhibitor of vascular smooth muscle growth and carotid intima formation. Circulation. 126: 2418-27. PMID 23065385 DOI: 10.1161/Circulationaha.112.125971  0.352
2012 Kim GY, Nigro P, Fujiwara K, Abe J, Berk BC. p62 binding to protein kinase C ζ regulates tumor necrosis factor α-induced apoptotic pathway in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2974-80. PMID 23023376 DOI: 10.1161/Atvbaha.112.300054  0.454
2012 Bell RD, Winkler EA, Singh I, Sagare AP, Deane R, Wu Z, Holtzman DM, Betsholtz C, Armulik A, Sallstrom J, Berk BC, Zlokovic BV. Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature. 485: 512-6. PMID 22622580 DOI: 10.1038/Nature11087  0.312
2012 Spindel ON, Yan C, Berk BC. Thioredoxin-interacting protein mediates nuclear-to-plasma membrane communication: role in vascular endothelial growth factor 2 signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1264-70. PMID 22345166 DOI: 10.1161/Atvbaha.111.244681  0.807
2012 Wang XQ, Nigro P, World C, Fujiwara K, Yan C, Berk BC. Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2. Circulation Research. 110: 560-8. PMID 22267843 DOI: 10.1161/Circresaha.111.256362  0.434
2012 Spindel ON, Berk BC. Redox redux: protecting the ischemic myocardium. The Journal of Clinical Investigation. 122: 30-2. PMID 22201673 DOI: 10.1172/Jci61467  0.752
2012 Spindel ON, World C, Berk BC. Thioredoxin interacting protein: redox dependent and independent regulatory mechanisms. Antioxidants & Redox Signaling. 16: 587-96. PMID 21929372 DOI: 10.1089/Ars.2011.4137  0.769
2012 Liu MW, Berk BC. Restenosis following coronary balloon angioplasty Role of smooth muscle cell proliferation. Trends in Cardiovascular Medicine. 1: 107-11. PMID 21239324 DOI: 10.1016/1050-1738(91)90003-W  0.339
2012 Abe J, Berk BC. Reactive oxygen species as mediators of signal transduction in cardiovascular disease. Trends in Cardiovascular Medicine. 8: 59-64. PMID 21235913 DOI: 10.1016/S1050-1738(97)00133-3  0.407
2012 Shi X, Yan C, Nadtochiy SM, Abe JI, Brookes PS, Berk BC. Corrigendum to p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: A pathogenic mechanism for ischemia-reperfusion injury [J. Mol. Cell. Cardiol. 51 (2011) 272-275] Journal of Molecular and Cellular Cardiology. 52: 292. DOI: 10.1016/J.Yjmcc.2011.11.006  0.379
2012 Smolock E, Berk BC. Chapter 98 – Vascular Smooth Muscle Cell Remodeling in Atherosclerosis and Restenosis Musclefundamental Biology and Mechanisms of Disease. 1301-1309. DOI: 10.1016/B978-0-12-381510-1.00098-3  0.416
2011 Pang J, Xu X, Getman MR, Shi X, Belmonte SL, Michaloski H, Mohan A, Blaxall BC, Berk BC. G protein coupled receptor kinase 2 interacting protein 1 (GIT1) is a novel regulator of mitochondrial biogenesis in heart. Journal of Molecular and Cellular Cardiology. 51: 769-76. PMID 21756914 DOI: 10.1016/J.Yjmcc.2011.06.020  0.307
2011 World C, Spindel ON, Berk BC. Thioredoxin-interacting protein mediates TRX1 translocation to the plasma membrane in response to tumor necrosis factor-α: a key mechanism for vascular endothelial growth factor receptor-2 transactivation by reactive oxygen species. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1890-7. PMID 21636804 DOI: 10.1161/Atvbaha.111.226340  0.812
2011 Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J. PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation. The Journal of Cell Biology. 193: 867-84. PMID 21624955 DOI: 10.1083/Jcb.201010051  0.408
2011 Shi X, Yan C, Nadtochiy SM, Abe J, Brookes PS, Berk BC. p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury. Journal of Molecular and Cellular Cardiology. 51: 272-5. PMID 21609719 DOI: 10.1016/J.Yjmcc.2011.05.005  0.322
2011 Satoh K, Berk BC, Shimokawa H. Vascular-derived reactive oxygen species for homeostasis and diseases. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 25: 211-5. PMID 21565278 DOI: 10.1016/J.Niox.2011.04.005  0.389
2011 Satoh K, Nigro P, Zeidan A, Soe NN, Jaffré F, Oikawa M, O'Dell MR, Cui Z, Menon P, Lu Y, Mohan A, Yan C, Blaxall BC, Berk BC. Cyclophilin A promotes cardiac hypertrophy in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1116-23. PMID 21330604 DOI: 10.1161/Atvbaha.110.214601  0.754
2011 Nigro P, Satoh K, O'Dell MR, Soe NN, Cui Z, Mohan A, Abe J, Alexis JD, Sparks JD, Berk BC. Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. The Journal of Experimental Medicine. 208: 53-66. PMID 21173104 DOI: 10.1084/Jem.20101174  0.387
2011 Nigro P, Abe J, Berk BC. Flow shear stress and atherosclerosis: a matter of site specificity. Antioxidants & Redox Signaling. 15: 1405-14. PMID 21050140 DOI: 10.1089/Ars.2010.3679  0.466
2010 Satoh K, Shimokawa H, Berk BC. Cyclophilin A: promising new target in cardiovascular therapy. Circulation Journal : Official Journal of the Japanese Circulation Society. 74: 2249-56. PMID 20962430 DOI: 10.1253/Circj.Cj-10-0904  0.348
2010 Wang J, Yin G, Menon P, Pang J, Smolock EM, Yan C, Berk BC. Phosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1976-82. PMID 20689073 DOI: 10.1161/Atvbaha.110.212415  0.807
2010 Menon P, Yin G, Smolock EM, Zuscik MJ, Yan C, Berk BC. GPCR kinase 2 interacting protein 1 (GIT1) regulates osteoclast function and bone mass. Journal of Cellular Physiology. 225: 777-85. PMID 20568227 DOI: 10.1002/Jcp.22282  0.772
2010 Nigro P, Abe J, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC. PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5. Blood. 116: 1971-9. PMID 20538799 DOI: 10.1182/Blood-2010-02-269134  0.499
2010 Cavet ME, Smolock EM, Menon P, Konishi A, Korshunov VA, Berk BC. Gas6-Axl pathway: the role of redox-dependent association of Axl with nonmuscle myosin IIB. Hypertension. 56: 105-11. PMID 20479336 DOI: 10.1161/Hypertensionaha.109.144642  0.801
2010 Jeon KI, Xu X, Aizawa T, Lim JH, Jono H, Kwon DS, Abe J, Berk BC, Li JD, Yan C. Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 107: 9795-800. PMID 20448200 DOI: 10.1073/Pnas.0914414107  0.347
2010 Menon P, Deane R, Sagare A, Lane SM, Zarcone TJ, O'Dell MR, Yan C, Zlokovic BV, Berk BC. Impaired spine formation and learning in GPCR kinase 2 interacting protein-1 (GIT1) knockout mice. Brain Research. 1317: 218-26. PMID 20043896 DOI: 10.1016/J.Brainres.2009.11.084  0.78
2010 Zhang N, Cai W, Yin G, Nagel DJ, Berk BC. GIT1 is a novel MEK1-ERK1/2 scaffold that localizes to focal adhesions. Cell Biology International. 34: 41-7. PMID 19947948 DOI: 10.1042/Cbi20090016  0.463
2010 Satoh K, Nigro P, Berk BC. Oxidative stress and vascular smooth muscle cell growth: a mechanistic linkage by cyclophilin A. Antioxidants & Redox Signaling. 12: 675-82. PMID 19747062 DOI: 10.1089/Ars.2009.2875  0.442
2009 Satoh K, Nigro P, Matoba T, O'Dell MR, Cui Z, Shi X, Mohan A, Yan C, Abe J, Illig KA, Berk BC. Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nature Medicine. 15: 649-56. PMID 19430489 DOI: 10.1038/Nm.1958  0.367
2009 Pan S, World CJ, Kovacs CJ, Berk BC. Glucose 6-phosphate dehydrogenase is regulated through c-Src-mediated tyrosine phosphorylation in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 895-901. PMID 19359662 DOI: 10.1161/Atvbaha.109.184812  0.46
2009 Pang J, Hoefen R, Pryhuber GS, Wang J, Yin G, White RJ, Xu X, O'Dell MR, Mohan A, Michaloski H, Massett MP, Yan C, Berk BC. G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular development. Circulation. 119: 1524-32. PMID 19273721 DOI: 10.1161/Circulationaha.108.823997  0.757
2009 Ibrahim J, Berk BC. Flow-mediated vascular remodeling in hypertension: relation to hemodyamics. Stroke; a Journal of Cerebral Circulation. 40: 582-90. PMID 19095986 DOI: 10.1161/Strokeaha.108.529826  0.32
2009 Alexis JD, Wang N, Che W, Lerner-Marmarosh N, Sahni A, Korshunov VA, Zou Y, Ding B, Yan C, Berk BC, Abe J. Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells. Circulation Research. 104: 69-78. PMID 19023129 DOI: 10.1161/Circresaha.108.188409  0.469
2009 Wang J, Taba Y, Pang J, Yin G, Yan C, Berk BC. GIT1 mediates VEGF-induced podosome formation in endothelial cells: critical role for PLCgamma. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 202-8. PMID 19023093 DOI: 10.1161/Atvbaha.108.174391  0.479
2009 Plekhanova O, Berk BC, Bashtrykov P, Brooks AI, Tkachuk V, Parfyonova Y. Oligonucleotide microarrays reveal regulated genes related to inward arterial remodeling induced by urokinase plasminogen activator. Journal of Vascular Research. 46: 177-87. PMID 18812699 DOI: 10.1159/000156703  0.366
2008 Reinhart-King CA, Fujiwara K, Berk BC. Physiologic stress-mediated signaling in the endothelium. Methods in Enzymology. 443: 25-44. PMID 18772009 DOI: 10.1016/S0076-6879(08)02002-8  0.415
2008 Satoh K, Matoba T, Suzuki J, O'Dell MR, Nigro P, Cui Z, Mohan A, Pan S, Li L, Jin ZG, Yan C, Abe J, Berk BC. Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation. Circulation. 117: 3088-98. PMID 18541741 DOI: 10.1161/Circulationaha.107.756106  0.423
2008 Cavet ME, Pang J, Yin G, Berk BC. An epidermal growth factor (EGF) -dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3607-16. PMID 18523162 DOI: 10.1096/Fj.07-094086  0.371
2008 Korshunov VA, Berk BC. Smooth muscle apoptosis and vascular remodeling. Current Opinion in Hematology. 15: 250-4. PMID 18391793 DOI: 10.1097/Moh.0B013E3282F97D71  0.385
2008 Li L, Tatake RJ, Natarajan K, Taba Y, Garin G, Tai C, Leung E, Surapisitchat J, Yoshizumi M, Yan C, Abe J, Berk BC. Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochemical and Biophysical Research Communications. 370: 159-63. PMID 18358237 DOI: 10.1016/J.Bbrc.2008.03.051  0.456
2008 Berk BC. Atheroprotective signaling mechanisms activated by steady laminar flow in endothelial cells. Circulation. 117: 1082-9. PMID 18299513 DOI: 10.1161/Circulationaha.107.720730  0.353
2008 Pang J, Yan C, Natarajan K, Cavet ME, Massett MP, Yin G, Berk BC. GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 892-8. PMID 18292392 DOI: 10.1161/Atvbaha.107.161349  0.406
2008 Cavet ME, Smolock EM, Ozturk OH, World C, Pang J, Konishi A, Berk BC. Gas6-axl receptor signaling is regulated by glucose in vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 886-91. PMID 18292389 DOI: 10.1161/Atvbaha.108.162693  0.405
2008 Mathews MT, Berk BC. PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 711-7. PMID 18239155 DOI: 10.1161/Atvbaha.107.156406  0.478
2008 Satoh K, Berk BC. Circulating smooth muscle progenitor cells: novel players in plaque stability. Cardiovascular Research. 77: 445-7. PMID 18056759 DOI: 10.1093/Cvr/Cvm088  0.376
2007 Korshunov VA, Daul M, Massett MP, Berk BC. Axl mediates vascular remodeling induced by deoxycorticosterone acetate-salt hypertension. Hypertension. 50: 1057-62. PMID 17923589 DOI: 10.1161/Hypertensionaha.107.096289  0.303
2007 Chen C, Korshunov VA, Massett MP, Yan C, Berk BC. Impaired vasorelaxation in inbred mice is associated with alterations in both nitric oxide and super oxide pathways. Journal of Vascular Research. 44: 504-12. PMID 17664889 DOI: 10.1159/000106751  0.32
2007 Korshunov VA, Schwartz SM, Berk BC. Vascular remodeling: hemodynamic and biochemical mechanisms underlying Glagov's phenomenon. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1722-8. PMID 17541029 DOI: 10.1161/Atvbaha.106.129254  0.36
2007 Garin G, Abe J, Mohan A, Lu W, Yan C, Newby AC, Rhaman A, Berk BC. Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing. Circulation Research. 101: 97-105. PMID 17525369 DOI: 10.1161/Circresaha.107.148270  0.403
2007 Wang J, Pan S, Berk BC. Glutaredoxin mediates Akt and eNOS activation by flow in a glutathione reductase-dependent manner. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1283-8. PMID 17431186 DOI: 10.1161/Atvbaha.107.144659  0.434
2007 Pan S, Berk BC. Glutathiolation regulates tumor necrosis factor-alpha-induced caspase-3 cleavage and apoptosis: key role for glutaredoxin in the death pathway. Circulation Research. 100: 213-9. PMID 17185628 DOI: 10.1161/01.Res.0000256089.30318.20  0.322
2007 World CJ, Garin G, Berk B. Vascular shear stress and activation of inflammatory genes. Current Atherosclerosis Reports. 8: 240-4. PMID 16640961 DOI: 10.1007/S11883-006-0079-8  0.402
2007 Alexis J, Che W, Ding B, Ito S, Wang N, McClain C, Korshunov V, Berk BC, Yan C, Abe J. 19 BCR SERINE/THREONINE KINASE ENHANCES ANGIOTENSIN II-MEDIATED NUCLEAR FACTOR κB TRANSCRIPTIONAL ACTIVATION IN VASCULAR SMOOTH MUSCLE CELLS VIA INHIBITION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ. Journal of Investigative Medicine. 55: S351.1-S351. DOI: 10.1136/Jim-55-02-19  0.429
2006 Garin G, Berk BC. Flow-mediated signaling modulates endothelial cell phenotype. Endothelium : Journal of Endothelial Cell Research. 13: 375-84. PMID 17169770 DOI: 10.1080/10623320601061599  0.401
2006 World CJ, Yamawaki H, Berk BC. Thioredoxin in the cardiovascular system. Journal of Molecular Medicine (Berlin, Germany). 84: 997-1003. PMID 17021908 DOI: 10.1007/S00109-006-0109-6  0.376
2006 Barker TA, Massett MP, Korshunov VA, Mohan AM, Kennedy AJ, Berk BC. Angiotensin II type 2 receptor expression after vascular injury: differing effects of angiotensin-converting enzyme inhibition and angiotensin receptor blockade. Hypertension. 48: 942-9. PMID 16982965 DOI: 10.1161/01.Hyp.0000241061.51003.B7  0.369
2006 Menshikov M, Torosyan N, Elizarova E, Plakida K, Vorotnikov A, Parfyonova Y, Stepanova V, Bobik A, Berk B, Tkachuk V. Urokinase induces matrix metalloproteinase-9/gelatinase B expression in THP-1 monocytes via ERK1/2 and cytosolic phospholipase A2 activation and eicosanoid production. Journal of Vascular Research. 43: 482-90. PMID 16926552 DOI: 10.1159/000095248  0.322
2006 Natarajan K, Berk BC. Crosstalk coregulation mechanisms of G protein-coupled receptors and receptor tyrosine kinases. Methods in Molecular Biology (Clifton, N.J.). 332: 51-77. PMID 16878685 DOI: 10.1385/1-59745-048-0:51  0.4
2006 Maekawa N, Abe J, Shishido T, Itoh S, Ding B, Sharma VK, Sheu SS, Blaxall BC, Berk BC. Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury. Circulation. 113: 2516-23. PMID 16717153 DOI: 10.1161/Circulationaha.105.563486  0.381
2006 Korshunov VA, Mohan AM, Georger MA, Berk BC. Axl, a receptor tyrosine kinase, mediates flow-induced vascular remodeling. Circulation Research. 98: 1446-52. PMID 16627783 DOI: 10.1161/01.Res.0000223322.16149.9A  0.466
2006 Hoefen RJ, Berk BC. The multifunctional GIT family of proteins. Journal of Cell Science. 119: 1469-75. PMID 16598076 DOI: 10.1242/Jcs.02925  0.772
2006 Suzuki J, Jin ZG, Meoli DF, Matoba T, Berk BC. Cyclophilin A is secreted by a vesicular pathway in vascular smooth muscle cells. Circulation Research. 98: 811-7. PMID 16527992 DOI: 10.1161/01.Res.0000216405.85080.A6  0.423
2006 Nagel DJ, Aizawa T, Jeon KI, Liu W, Mohan A, Wei H, Miano JM, Florio VA, Gao P, Korshunov VA, Berk BC, Yan C. Role of nuclear Ca2+/calmodulin-stimulated phosphodiesterase 1A in vascular smooth muscle cell growth and survival. Circulation Research. 98: 777-84. PMID 16514069 DOI: 10.1161/01.Res.0000215576.27615.Fd  0.425
2006 Berk BC, Korshunov VA. Genetic determinants of vascular remodelling. The Canadian Journal of Cardiology. 22: 6B-11B. PMID 16498506 DOI: 10.1016/S0828-282X(06)70980-1  0.374
2006 Menshikov M, Plekhanova O, Cai H, Chalupsky K, Parfyonova Y, Bashtrikov P, Tkachuk V, Berk BC. Urokinase plasminogen activator stimulates vascular smooth muscle cell proliferation via redox-dependent pathways. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 801-7. PMID 16456094 DOI: 10.1161/01.Atv.0000207277.27432.15  0.437
2006 Shen WL, Gao PJ, Che ZQ, Ji KD, Yin M, Yan C, Berk BC, Zhu DL. NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation. Biochemical and Biophysical Research Communications. 339: 337-43. PMID 16298339 DOI: 10.1016/J.Bbrc.2005.10.207  0.391
2006 Korshunov VA, Nikonenko TA, Tkachuk VA, Brooks A, Berk BC. Interleukin-18 and macrophage migration inhibitory factor are associated with increased carotid intima-media thickening. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 295-300. PMID 16293799 DOI: 10.1161/01.Atv.0000196544.73761.82  0.305
2006 ABE J, CHE W, YOSHIZUMI M, HUANG Q, GLASSMAN M, OHTA S, WU Y, ARLINGHAUS R, BERK BC. Bcr in Vascular Smooth Muscle Cells Annals of the New York Academy of Sciences. 947: 341-343. DOI: 10.1111/J.1749-6632.2001.Tb03959.X  0.435
2006 World C, Berk B. Reactive oxygen species-mediated regulation of thioredoxin translocation in vascular smooth muscle cells Vascular Pharmacology. 45: 188. DOI: 10.1016/J.Vph.2006.08.039  0.359
2005 Garin G, Mathews M, Berk BC. Tissue-resident bone marrow-derived progenitor cells: key players in hypoxia-induced angiogenesis. Circulation Research. 97: 955-7. PMID 16284185 DOI: 10.1161/01.Res.0000193566.65262.D8  0.375
2005 Ding B, Abe J, Wei H, Xu H, Che W, Aizawa T, Liu W, Molina CA, Sadoshima J, Blaxall BC, Berk BC, Yan C. A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 14771-6. PMID 16186489 DOI: 10.1073/Pnas.0506489102  0.379
2005 Watanabe T, Suzuki J, Yamawaki H, Sharma VK, Sheu SS, Berk BC. Losartan metabolite EXP3179 activates Akt and endothelial nitric oxide synthase via vascular endothelial growth factor receptor-2 in endothelial cells: angiotensin II type 1 receptor-independent effects of EXP3179. Circulation. 112: 1798-805. PMID 16172287 DOI: 10.1161/Circulationaha.104.509760  0.493
2005 Tai LK, Zheng Q, Pan S, Jin ZG, Berk BC. Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2. The Journal of Biological Chemistry. 280: 29620-4. PMID 15985432 DOI: 10.1074/Jbc.M501243200  0.815
2005 Yin G, Zheng Q, Yan C, Berk BC. GIT1 is a scaffold for ERK1/2 activation in focal adhesions. The Journal of Biological Chemistry. 280: 27705-12. PMID 15923189 DOI: 10.1074/Jbc.M502271200  0.683
2005 Pi X, Garin G, Xie L, Zheng Q, Wei H, Abe J, Yan C, Berk BC. BMK1/ERK5 is a novel regulator of angiogenesis by destabilizing hypoxia inducible factor 1alpha. Circulation Research. 96: 1145-51. PMID 15879308 DOI: 10.1161/01.Res.0000168802.43528.E1  0.804
2005 Ding B, Abe JI, Wei H, Huang Q, Walsh RA, Molina CA, Zhao A, Sadoshima J, Blaxall BC, Berk BC, Yan C. Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: Implication in heart failure Circulation. 111: 2469-2476. PMID 15867171 DOI: 10.1161/01.Cir.0000165128.39715.87  0.34
2005 Blaxall BC, Miano JM, Berk BC. Angiotensin II: a devious activator of mineralocorticoid receptor-dependent gene expression. Circulation Research. 96: 610-1. PMID 15802618 DOI: 10.1161/01.Res.0000162163.75564.8B  0.351
2005 Yamawaki H, Pan S, Lee RT, Berk BC. Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin-interacting protein in endothelial cells. The Journal of Clinical Investigation. 115: 733-8. PMID 15696199 DOI: 10.1172/Jci200523001  0.471
2005 Jin ZG, Wong C, Wu J, Berk BC. Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells. The Journal of Biological Chemistry. 280: 12305-9. PMID 15665327 DOI: 10.1074/Jbc.M500294200  0.518
2005 Watanabe T, Barker TA, Berk BC. Angiotensin II and the endothelium: diverse signals and effects. Hypertension. 45: 163-9. PMID 15630047 DOI: 10.1161/01.Hyp.0000153321.13792.B9  0.355
2005 Kim D, Aizawa T, Wei H, Pi X, Rybalkin SD, Berk BC, Yan C. Angiotensin II increases phosphodiesterase 5A expression in vascular smooth muscle cells: a mechanism by which angiotensin II antagonizes cGMP signaling. Journal of Molecular and Cellular Cardiology. 38: 175-84. PMID 15623434 DOI: 10.1016/J.Yjmcc.2004.10.013  0.724
2005 Amerongen GPvN, Hinsbergh VWMv, Berk BC. Chapter 14 Chronic lung vascular hyperpermeability Advances in Molecular and Cell Biology. 35: 401-422. DOI: 10.1016/S1569-2558(05)35014-4  0.383
2004 Korshunov VA, Solomatina MA, Plekhanova OS, Parfyonova YV, Tkachuk VA, Berk BC. Plasminogen activator expression correlates with genetic differences in vascular remodeling. Journal of Vascular Research. 41: 481-90. PMID 15528930 DOI: 10.1159/000081804  0.317
2004 Lungu AO, Jin ZG, Yamawaki H, Tanimoto T, Wong C, Berk BC. Cyclosporin A inhibits flow-mediated activation of endothelial nitric-oxide synthase by altering cholesterol content in caveolae. The Journal of Biological Chemistry. 279: 48794-800. PMID 15383526 DOI: 10.1074/Jbc.M313897200  0.5
2004 Melaragno MG, Cavet ME, Yan C, Tai LK, Jin ZG, Haendeler J, Berk BC. Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt. Journal of Molecular and Cellular Cardiology. 37: 881-7. PMID 15380678 DOI: 10.1016/J.Yjmcc.2004.06.018  0.823
2004 Akaike M, Che W, Marmarosh NL, Ohta S, Osawa M, Ding B, Berk BC, Yan C, Abe J. The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in endothelial cells. Molecular and Cellular Biology. 24: 8691-704. PMID 15367687 DOI: 10.1128/Mcb.24.19.8691-8704.2004  0.487
2004 Korshunov VA, Berk BC. Strain-dependent vascular remodeling: the "Glagov phenomenon" is genetically determined. Circulation. 110: 220-6. PMID 15226209 DOI: 10.1161/01.Cir.0000134958.88379.2E  0.302
2004 Parfyonova Y, Plekhanova O, Solomatina M, Naumov V, Bobik A, Berk B, Tkachuk V. Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury. Journal of Vascular Research. 41: 268-76. PMID 15192267 DOI: 10.1159/000078825  0.32
2004 Jin ZG, Lungu AO, Xie L, Wang M, Wong C, Berk BC. Cyclophilin A is a proinflammatory cytokine that activates endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1186-91. PMID 15130913 DOI: 10.1161/01.Atv.0000130664.51010.28  0.41
2004 Konishi A, Aizawa T, Mohan A, Korshunov VA, Berk BC. Hydrogen peroxide activates the Gas6-Axl pathway in vascular smooth muscle cells. The Journal of Biological Chemistry. 279: 28766-70. PMID 15123721 DOI: 10.1074/Jbc.M401977200  0.441
2004 Jin ZG, Berk BC. SOXF: redox mediators of vascular smooth muscle cell growth. Heart (British Cardiac Society). 90: 488-90. PMID 15084536 DOI: 10.1136/Hrt.2003.029371  0.489
2004 Osawa M, Itoh S, Ohta S, Huang Q, Berk BC, Marmarosh NL, Che W, Ding B, Yan C, Abe J. ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear accumulation. The Journal of Biological Chemistry. 279: 29691-9. PMID 15078886 DOI: 10.1074/Jbc.M309371200  0.429
2004 Natarajan K, Yin G, Berk BC. Scaffolds direct Src-specific signaling in response to angiotensin II: new roles for Cas and GIT1. Molecular Pharmacology. 65: 822-5. PMID 15044610 DOI: 10.1124/Mol.65.4.822  0.311
2004 Tanimoto T, Lungu AO, Berk BC. Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells. Circulation Research. 94: 1050-8. PMID 15044318 DOI: 10.1161/01.Res.0000126404.41421.Be  0.422
2004 van Nieuw Amerongen GP, Natarajan K, Yin G, Hoefen RJ, Osawa M, Haendeler J, Ridley AJ, Fujiwara K, van Hinsbergh VW, Berk BC. GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions. Circulation Research. 94: 1041-9. PMID 15016733 DOI: 10.1161/01.Res.0000125627.77235.0C  0.802
2004 Korshunov VA, Massett MP, Carey RM, Berk BC. Role of Angiotensin-converting enzyme and neutral endopeptidase in flow-dependent remodeling. Journal of Vascular Research. 41: 148-56. PMID 15004434 DOI: 10.1159/000077144  0.33
2004 Yin G, Haendeler J, Yan C, Berk BC. GIT1 functions as a scaffold for MEK1-extracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor. Molecular and Cellular Biology. 24: 875-85. PMID 14701758 DOI: 10.1128/Mcb.24.2.875-885.2004  0.485
2004 Zheng Q, Yin G, Yan C, Cavet M, Berk BC. 14-3-3beta binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function. The Journal of Biological Chemistry. 279: 8787-91. PMID 14679215 DOI: 10.1074/Jbc.M310212200  0.638
2004 Pi X, Yan C, Berk BC. Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circulation Research. 94: 362-9. PMID 14670836 DOI: 10.1161/01.Res.0000112406.27800.6F  0.763
2004 Yoshizumi M, Abe J, Tsuchiya K, Berk BC, Tamaki T. Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases. Journal of Pharmacological Sciences. 91: 172-6. PMID 12686737 DOI: 10.1254/Jphs.91.172  0.476
2004 Pi X, Yan C, Berk BC. Atheroprotective mechanisms of flow: inhibition of apoptosis International Congress Series. 1262: 129-132. DOI: 10.1016/J.ICS.2003.11.036  0.666
2003 Yamawaki H, Haendeler J, Berk BC. Thioredoxin: a key regulator of cardiovascular homeostasis. Circulation Research. 93: 1029-33. PMID 14645133 DOI: 10.1161/01.Res.0000102869.39150.23  0.396
2003 Korshunov VA, Berk BC. Flow-induced vascular remodeling in the mouse: a model for carotid intima-media thickening. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 2185-91. PMID 14576075 DOI: 10.1161/01.Atv.0000103120.06092.14  0.347
2003 Haendeler J, Yin G, Hojo Y, Saito Y, Melaragno M, Yan C, Sharma VK, Heller M, Aebersold R, Berk BC. GIT1 mediates Src-dependent activation of phospholipase Cgamma by angiotensin II and epidermal growth factor. The Journal of Biological Chemistry. 278: 49936-44. PMID 14523024 DOI: 10.1074/Jbc.M307317200  0.464
2003 Yamawaki H, Lehoux S, Berk BC. Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo. Circulation. 108: 1619-25. PMID 12963644 DOI: 10.1161/01.Cir.0000089373.49941.C4  0.363
2003 Lerner-Marmarosh N, Yoshizumi M, Che W, Surapisitchat J, Kawakatsu H, Akaike M, Ding B, Huang Q, Yan C, Berk BC, Abe J. Inhibition of tumor necrosis factor-[alpha]-induced SHP-2 phosphatase activity by shear stress: a mechanism to reduce endothelial inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1775-81. PMID 12947019 DOI: 10.1161/01.Atv.0000094432.98445.36  0.442
2003 Aizawa T, Wei H, Miano JM, Abe J, Berk BC, Yan C. Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells. Circulation Research. 93: 406-13. PMID 12919948 DOI: 10.1161/01.Res.0000091074.33584.F0  0.418
2003 Jin ZG, Ueba H, Tanimoto T, Lungu AO, Frame MD, Berk BC. Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase. Circulation Research. 93: 354-63. PMID 12893742 DOI: 10.1161/01.Res.0000089257.94002.96  0.512
2003 Konishi A, Berk BC. Epidermal growth factor receptor transactivation is regulated by glucose in vascular smooth muscle cells. The Journal of Biological Chemistry. 278: 35049-56. PMID 12829718 DOI: 10.1074/Jbc.M304913200  0.37
2003 Berk BC. Angiotensin type 2 receptor (AT2R): a challenging twin. Science's Stke : Signal Transduction Knowledge Environment. 2003: PE16. PMID 12734384 DOI: 10.1126/Stke.2003.181.Pe16  0.368
2003 Ibrahim J, Miyashiro JK, Berk BC. Shear stress is differentially regulated among inbred rat strains. Circulation Research. 92: 1001-9. PMID 12676815 DOI: 10.1161/01.Res.0000069687.54486.B1  0.351
2003 Yin G, Yan C, Berk BC. Angiotensin II signaling pathways mediated by tyrosine kinases. The International Journal of Biochemistry & Cell Biology. 35: 780-3. PMID 12676164 DOI: 10.1016/S1357-2725(02)00300-X  0.424
2003 Ogata Y, Takahashi M, Ueno S, Takeuchi K, Okada T, Mano H, Ookawara S, Ozawa K, Berk BC, Ikeda U, Shimada K, Kobayashi E. Antiapoptotic effect of endothelin-1 in rat cardiomyocytes in vitro. Hypertension (Dallas, Tex. : 1979). 41: 1156-63. PMID 12668584 DOI: 10.1161/01.Hyp.0000064342.30653.24  0.376
2003 Cavet ME, Lehoux S, Berk BC. 14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity. The Journal of Biological Chemistry. 278: 18376-83. PMID 12618428 DOI: 10.1074/Jbc.M208475200  0.385
2003 Yan C, Kim D, Aizawa T, Berk BC. Functional interplay between angiotensin II and nitric oxide: cyclic GMP as a key mediator. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 26-36. PMID 12524221 DOI: 10.1161/01.Atv.0000046231.17365.9D  0.343
2003 Plekhanova O, Solomatina M, Viborov O, Bashtrikov P, Brooks A, Naumov V, Tkachuk V, Berk B, Parfyonova Y. 4P-1140 Oligonucleotide microarrays reveal regulated genes causing opposite arterial remodeling induced by Plasminogen activators Atherosclerosis Supplements. 4: 325. DOI: 10.1016/S1567-5688(03)91396-1  0.314
2003 Aizawa T, Wei H, Miano J, Abe J, Berk B, Yan C. 4P-1112 Anti-inflammatory effects of NO/cGMP are mediated by PDE3 inhibition in vascular smooth muscle cells Atherosclerosis Supplements. 4: 319. DOI: 10.1016/S1567-5688(03)91368-7  0.35
2003 Jin Z, Liao D, Berk B. 4P-1065 Secreted heat shock protein 90-alpha is a novel mediator of oxidative stress via pro-inflammatory effects on vascular cells Atherosclerosis Supplements. 4: 308-309. DOI: 10.1016/S1567-5688(03)91322-5  0.351
2003 Berk B, Yamawaki H, Lehoux S, Yoshizumi M, Min W, Abe J, Yan C. 4SY09-2 Atheroprotective mechanisms activated by flow Atherosclerosis Supplements. 4: 266. DOI: 10.1016/S1567-5688(03)91145-7  0.315
2002 Berk BC, Min W, Yan C, Surapisitchat J, Liu Y, Hoefen R. Atheroprotective Mechanisms Activated by Fluid Shear Stress in Endothelial Cells. Drug News & Perspectives. 15: 133-139. PMID 12677255 DOI: 10.1358/Dnp.2002.15.3.704684  0.803
2002 Hoefen RJ, Berk BC. The role of MAP kinases in endothelial activation. Vascular Pharmacology. 38: 271-3. PMID 12487031 DOI: 10.1016/S1537-1891(02)00251-3  0.8
2002 Tai LK, Okuda M, Abe J, Yan C, Berk BC. Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1790-6. PMID 12426206 DOI: 10.1161/01.Atv.0000034475.40227.40  0.814
2002 Hojo Y, Saito Y, Tanimoto T, Hoefen RJ, Baines CP, Yamamoto K, Haendeler J, Asmis R, Berk BC. Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism. Circulation Research. 91: 712-8. PMID 12386148 DOI: 10.1161/01.Res.0000037981.97541.25  0.781
2002 Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, Dimmeler S. Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nature Cell Biology. 4: 743-9. PMID 12244325 DOI: 10.1038/Ncb851  0.352
2002 Tanimoto T, Jin ZG, Berk BC. Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS). The Journal of Biological Chemistry. 277: 42997-3001. PMID 12226078 DOI: 10.1074/Jbc.M204764200  0.475
2002 Pi X, Yan C, Kim D, Chen J, Berk BC. Differential expression of genes from nitrate-tolerant rat aorta. Journal of Vascular Research. 39: 304-10. PMID 12187120 DOI: 10.1159/000065542  0.685
2002 Abe J, Berk BC. Hypoxia and HIF-1alpha stability: another stress-sensing mechanism for Shc. Circulation Research. 91: 4-6. PMID 12114314 DOI: 10.1161/01.Res.0000026654.65882.55  0.465
2002 Huang Q, Lerner-Marmarosh N, Che W, Ohta S, Osawa M, Yoshizumi M, Glassman M, Yan C, Berk BC, Abe J. The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation. The Journal of Biological Chemistry. 277: 29330-41. PMID 12011040 DOI: 10.1074/Jbc.M112450200  0.366
2002 Frame MD, Fox RJ, Kim D, Mohan A, Berk BC, Yan C. Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2377-85. PMID 12003849 DOI: 10.1152/Ajpheart.00429.2001  0.326
2002 Saito Y, Hojo Y, Tanimoto T, Abe J, Berk BC. Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor. The Journal of Biological Chemistry. 277: 23216-22. PMID 11940581 DOI: 10.1074/Jbc.M200605200  0.454
2002 Saito Y, Berk BC. Angiotensin II-mediated signal transduction pathways. Current Hypertension Reports. 4: 167-71. PMID 11884273 DOI: 10.1007/S11906-002-0042-1  0.383
2002 Takeishi Y, Huang Q, Abe J, Che W, Lee JD, Kawakatsu H, Hoit BD, Berk BC, Walsh RA. Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy. Cardiovascular Research. 53: 131-7. PMID 11744021 DOI: 10.1016/S0008-6363(01)00438-2  0.426
2001 Berk BC, Abe JI, Min W, Surapisitchat J, Yan C. Endothelial atheroprotective and anti-inflammatory mechanisms. Annals of the New York Academy of Sciences. 947: 93-109; discussion 1. PMID 11795313 DOI: 10.1111/J.1749-6632.2001.Tb03932.X  0.499
2001 Takeishi Y, Huang Q, Wang T, Glassman M, Yoshizumi M, Baines CP, Lee JD, Kawakatsu H, Che W, Lerner-Marmarosh N, Zhang C, Yan C, Ohta S, Walsh RA, Berk BC, et al. Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: modulation of MAP kinases activation by ischemic preconditioning. Journal of Molecular and Cellular Cardiology. 33: 1989-2005. PMID 11708843 DOI: 10.1006/Jmcc.2001.1463  0.404
2001 Kim D, Rybalkin SD, Pi X, Wang Y, Zhang C, Munzel T, Beavo JA, Berk BC, Yan C. Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate tolerance. Circulation. 104: 2338-43. PMID 11696475 DOI: 10.1161/Hc4401.098432  0.722
2001 Che W, Abe J, Yoshizumi M, Huang Q, Glassman M, Ohta S, Melaragno MG, Poppa V, Yan C, Lerner-Marmarosh N, Zhang C, Wu Y, Arlinghaus R, Berk BC. p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells. Circulation. 104: 1399-406. PMID 11560856 DOI: 10.1161/Hc3701.095581  0.466
2001 Takeishi Y, Huang Q, Abe J, Glassman M, Che W, Lee JD, Kawakatsu H, Lawrence EG, Hoit BD, Berk BC, Walsh RA. Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch. Journal of Molecular and Cellular Cardiology. 33: 1637-48. PMID 11549343 DOI: 10.1006/Jmcc.2001.1427  0.375
2001 Saito Y, Haendeler J, Hojo Y, Yamamoto K, Berk BC. Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation. Molecular and Cellular Biology. 21: 6387-94. PMID 11533228 DOI: 10.1128/Mcb.21.19.6387-6394.2001  0.394
2001 Berk BC. Vascular smooth muscle growth: autocrine growth mechanisms. Physiological Reviews. 81: 999-1030. PMID 11427690 DOI: 10.1152/Physrev.2001.81.3.999  0.365
2001 Surapisitchat J, Hoefen RJ, Pi X, Yoshizumi M, Yan C, Berk BC. Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members. Proceedings of the National Academy of Sciences of the United States of America. 98: 6476-81. PMID 11353829 DOI: 10.1073/Pnas.101134098  0.8
2001 Miano JM, Berk BC. Retinoids: new insight into smooth muscle cell growth inhibition. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 724-6. PMID 11348864 DOI: 10.1161/01.Atv.21.5.724  0.373
2001 Liu Y, Yin G, Surapisitchat J, Berk BC, Min W. Laminar flow inhibits TNF-induced ASK1 activation by preventing dissociation of ASK1 from its inhibitor 14-3-3. The Journal of Clinical Investigation. 107: 917-23. PMID 11285311 DOI: 10.1172/Jci11947  0.453
2001 Lehoux S, Abe JI, Florian JA, Berk BC. 14-3-3 Binding to Na+/H+ Exchanger Isoform-1 is Associated with Serum-dependent Activation of Na+/H+ Exchange Journal of Biological Chemistry. 276: 15794-15800. PMID 11279064 DOI: 10.1074/Jbc.M100410200  0.368
2001 Chen K, Vita JA, Berk BC, Keaney JF. c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation. The Journal of Biological Chemistry. 276: 16045-50. PMID 11278982 DOI: 10.1074/Jbc.M011766200  0.451
2001 Yan C, Luo H, Lee JD, Abe J, Berk BC. Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains. The Journal of Biological Chemistry. 276: 10870-8. PMID 11139578 DOI: 10.1074/Jbc.M009286200  0.424
2001 Saito Y, Berk BC. Transactivation: a novel signaling pathway from angiotensin II to tyrosine kinase receptors. Journal of Molecular and Cellular Cardiology. 33: 3-7. PMID 11133218 DOI: 10.1006/Jmcc.2000.1272  0.391
2001 Melaragno MG, Fridell YW, Berk BC. The Gas6/Axl system: a novel regulator of vascular cell function. Trends in Cardiovascular Medicine. 9: 250-3. PMID 11094334 DOI: 10.1016/S1050-1738(00)00027-X  0.437
2001 Haendeler J, Berk BC. Angiotensin II mediated signal transduction. Important role of tyrosine kinases. Regulatory Peptides. 95: 1-7. PMID 11062326 DOI: 10.1016/S0167-0115(00)00133-6  0.437
2000 Ou H, Haendeler J, Aebly MR, Kelly LA, Cholewa BC, Koike G, Kwitek-Black A, Jacob HJ, Berk BC, Miano JM. Retinoic acid-induced tissue transglutaminase and apoptosis in vascular smooth muscle cells Circulation Research. 87: 881-887. PMID 11073883 DOI: 10.1161/01.Res.87.10.881  0.428
2000 Jin ZG, Melaragno MG, Liao DF, Yan C, Haendeler J, Suh YA, Lambeth JD, Berk BC. Cyclophilin A is a secreted growth factor induced by oxidative stress. Circulation Research. 87: 789-96. PMID 11055983 DOI: 10.1161/01.Res.87.9.789  0.45
2000 Miano JM, Berk BC. Retinoids: versatile biological response modifiers of vascular smooth muscle phenotype. Circulation Research. 87: 355-62. PMID 10969032 DOI: 10.1161/01.Res.87.5.355  0.373
2000 Berk BC, Haendeler J, Sottile J. Angiotensin II, atherosclerosis, and aortic aneurysms. The Journal of Clinical Investigation. 105: 1525-6. PMID 10841510 DOI: 10.1172/Jci9820  0.39
2000 Yoshizumi M, Abe J, Haendeler J, Huang Q, Berk BC. Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species. The Journal of Biological Chemistry. 275: 11706-12. PMID 10766791 DOI: 10.1074/Jbc.275.16.11706  0.414
2000 Haendeler J, Ishida M, Hunyady L, Berk BC. The third cytoplasmic loop of the angiotensin II type 1 receptor exerts differential effects on extracellular signal-regulated kinase (ERK1/ERK2) and apoptosis via Ras- and Rap1-dependent pathways. Circulation Research. 86: 729-36. PMID 10764405 DOI: 10.1161/01.Res.86.7.729  0.454
2000 Heeneman S, Haendeler J, Saito Y, Ishida M, Berk BC. Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc. The Journal of Biological Chemistry. 275: 15926-32. PMID 10748142 DOI: 10.1074/Jbc.M909616199  0.374
2000 Abe Ji, Baines CP, Berk BC. Role of mitogen-activated protein kinases in ischemia and reperfusion injury : the good and the bad. Circulation Research. 86: 607-9. PMID 10746992 DOI: 10.1161/01.Res.86.6.607  0.419
2000 Abe J, Okuda M, Huang Q, Yoshizumi M, Berk BC. Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras. The Journal of Biological Chemistry. 275: 1739-48. PMID 10636870 DOI: 10.1074/Jbc.275.3.1739  0.383
2000 Liao DF, Jin ZG, Baas AS, Daum G, Gygi SP, Aebersold R, Berk BC. Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells. The Journal of Biological Chemistry. 275: 189-96. PMID 10617604 DOI: 10.1074/Jbc.275.1.189  0.443
2000 Takeishi Y, Abe Ji, Lee JD, Kawakatsu H, Walsh RA, Berk BC. Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts. Circulation Research. 85: 1164-72. PMID 10590243 DOI: 10.1161/01.Res.85.12.1164  0.456
2000 Berk B. Angiotensin II signal transduction in smooth muscle cells: Na+/H+ exchanger (NHE-1) kinases as mediators of the hypertensive phenotype American Journal of Hypertension. 13: S317. DOI: 10.1016/S0895-7061(00)00794-9  0.378
1999 Gallis B, Corthals GL, Goodlett DR, Ueba H, Kim F, Presnell SR, Figeys D, Harrison DG, Berk BC, Aebersold R, Corson MA. Identification of flow-dependent endothelial nitric-oxide synthase phosphorylation sites by mass spectrometry and regulation of phosphorylation and nitric oxide production by the phosphatidylinositol 3-kinase inhibitor LY294002 Journal of Biological Chemistry. 274: 30101-30108. PMID 10514497 DOI: 10.1074/Jbc.274.42.30101  0.463
1999 Miano JM, Berk BC. NAB2: a transcriptional brake for activated gene expression in the vessel wall? The American Journal of Pathology. 155: 1009-12. PMID 10514380 DOI: 10.1016/S0002-9440(10)65200-5  0.334
1999 Okuda M, Takahashi M, Suero J, Murry CE, Traub O, Kawakatsu H, Berk BC. Shear stress stimulation of p130(cas) tyrosine phosphorylation requires calcium-dependent c-Src activation. The Journal of Biological Chemistry. 274: 26803-9. PMID 10480886 DOI: 10.1074/Jbc.274.38.26803  0.428
1999 Abe J, Berk BC. Fyn and JAK2 mediate Ras activation by reactive oxygen species. The Journal of Biological Chemistry. 274: 21003-10. PMID 10409649 DOI: 10.1074/Jbc.274.30.21003  0.391
1999 Peterson TE, Poppa V, Ueba H, Wu A, Yan C, Berk BC. Opposing effects of reactive oxygen species and cholesterol on endothelial nitric oxide synthase and endothelial cell caveolae. Circulation Research. 85: 29-37. PMID 10400908 DOI: 10.1161/01.Res.85.1.29  0.397
1999 Takahashi E, Abe J, Gallis B, Aebersold R, Spring DJ, Krebs EG, Berk BC. p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1. The Journal of Biological Chemistry. 274: 20206-14. PMID 10400637 DOI: 10.1074/Jbc.274.29.20206  0.385
1999 Traub O, Ishida T, Ishida M, Tupper JC, Berk BC. Shear stress-mediated extracellular signal-regulated kinase activation is regulated by sodium in endothelial cells. Potential role for a voltage-dependent sodium channel. The Journal of Biological Chemistry. 274: 20144-50. PMID 10400628 DOI: 10.1074/Jbc.274.29.20144  0.384
1999 Ishida T, Ishida M, Suero J, Takahashi M, Berk BC. Agonist-stimulated cytoskeletal reorganization and signal transduction at focal adhesions in vascular smooth muscle cells require c-Src. The Journal of Clinical Investigation. 103: 789-97. PMID 10079099 DOI: 10.1172/Jci4189  0.483
1999 Takahashi E, Berk BC. MAP kinases and vascular smooth muscle function. Acta Physiologica Scandinavica. 164: 611-21. PMID 9887983 DOI: 10.1111/J.1365-201X.1998.Tb10705.X  0.42
1999 Yan C, Takahashi M, Okuda M, Lee JD, Berk BC. Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium. The Journal of Biological Chemistry. 274: 143-50. PMID 9867822 DOI: 10.1074/Jbc.274.1.143  0.473
1999 Berk B. Redox Signals that Regulate the Vascular Response to Injury Thrombosis and Haemostasis. 82: 810-817. DOI: 10.1055/S-0037-1615916  0.481
1999 Berk BC. Flow-Dependent Protein Kinases: Role in no formation Journal of Vascular and Interventional Radiology. 10: 958. DOI: 10.1016/S1051-0443(99)70153-3  0.303
1998 Kusuhara M, Takahashi E, Peterson TE, Abe J, Ishida M, Han J, Ulevitch R, Berk BC. p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: effects on Na+/H+ exchange and ERK1/2. Circulation Research. 83: 824-31. PMID 9776729 DOI: 10.1161/01.Res.83.8.824  0.423
1998 Melaragno MG, Wuthrich DA, Poppa V, Gill D, Lindner V, Berk BC, Corson MA. Increased expression of Axl tyrosine kinase after vascular injury and regulation by G protein-coupled receptor agonists in rats. Circulation Research. 83: 697-704. PMID 9758639 DOI: 10.1161/01.Res.83.7.697  0.429
1998 Poppa V, Miyashiro JK, Corson MA, Berk BC. Endothelial NO synthase is increased in regenerating endothelium after denuding injury of the rat aorta. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 1312-21. PMID 9714139 DOI: 10.1161/01.Atv.18.8.1312  0.392
1998 Schmitz U, Ishida T, Ishida M, Surapisitchat J, Hasham MI, Pelech S, Berk BC. Angiotensin II stimulates p21-activated kinase in vascular smooth muscle cells: role in activation of JNK. Circulation Research. 82: 1272-8. PMID 9648723 DOI: 10.1161/01.Res.82.12.1272  0.461
1998 Traub O, Berk BC. Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 677-85. PMID 9598824 DOI: 10.1161/01.Atv.18.5.677  0.476
1998 Ishida M, Ishida T, Thomas SM, Berk BC. Activation of extracellular signal-regulated kinases (ERK1/2) by angiotensin II is dependent on c-Src in vascular smooth muscle cells. Circulation Research. 82: 7-12. PMID 9440699 DOI: 10.1161/01.Res.82.1.7  0.425
1998 Traub O, Monia BP, Dean NM, Berk BC. PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cells. The Journal of Biological Chemistry. 272: 31251-7. PMID 9395450 DOI: 10.1074/Jbc.272.50.31251  0.483
1998 Berk BC. Heart Failure Reviews. 3: 87-99. DOI: 10.1023/A:1009758627202  0.428
1997 Schmitz U, Berk BC. Angiotensin II signal transduction: Stimulation of multiple mitogen-activated protein kinase pathways. Trends in Endocrinology and Metabolism: Tem. 8: 261-6. PMID 18406813 DOI: 10.1016/S1043-2760(97)00101-X  0.456
1997 Schmitz U, Ishida M, Berk BC. Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma-associated proteins. Characterization of a c-Src-dependent 97-kD protein in vascular smooth muscle cells. Circulation Research. 81: 550-7. PMID 9314836 DOI: 10.1161/01.Res.81.4.550  0.421
1997 Mondy JS, Lindner V, Miyashiro JK, Berk BC, Dean RH, Geary RL. Platelet-derived growth factor ligand and receptor expression in response to altered blood flow in vivo. Circulation Research. 81: 320-7. PMID 9285633 DOI: 10.1161/01.Res.81.3.320  0.392
1997 Miyashiro JK, Poppa V, Berk BC. Flow-induced vascular remodeling in the rat carotid artery diminishes with age. Circulation Research. 81: 311-9. PMID 9285632 DOI: 10.1161/01.Res.81.3.311  0.328
1997 Abe Ji, Takahashi M, Ishida M, Lee JD, Berk BC. c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1. The Journal of Biological Chemistry. 272: 20389-94. PMID 9252345 DOI: 10.1074/Jbc.272.33.20389  0.442
1997 Takahashi E, Abe J, Berk BC. Angiotensin II stimulates p90rsk in vascular smooth muscle cells. A potential Na(+)-H+ exchanger kinase. Circulation Research. 81: 268-73. PMID 9242188 DOI: 10.1161/01.Res.81.2.268  0.461
1997 Takahashi M, Ishida T, Traub O, Corson MA, Berk BC. Mechanotransduction in endothelial cells: temporal signaling events in response to shear stress. Journal of Vascular Research. 34: 212-9. PMID 9226303 DOI: 10.1159/000159225  0.449
1997 Ishida M, Berk BC. Angiotensin II signal transduction in vascular smooth muscle cells: role of tyrosine kinases. The Keio Journal of Medicine. 46: 61-8. PMID 9212588 DOI: 10.2302/Kjm.46.61  0.445
1997 Ishida T, Takahashi M, Corson MA, Berk BC. Fluid shear stress-mediated signal transduction: how do endothelial cells transduce mechanical force into biological responses? Annals of the New York Academy of Sciences. 811: 12-23; discussion 23. PMID 9186580 DOI: 10.1111/J.1749-6632.1997.Tb51984.X  0.47
1997 Phan VN, Kusuhara M, Lucchesi PA, Berk BC. A 90-kD NA+-H+ exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells Hypertension. 29: 1265-1272. PMID 9180627 DOI: 10.1161/01.Hyp.29.6.1265  0.463
1997 Berk BC, Corson MA. Angiotensin II signal transduction in vascular smooth muscle: role of tyrosine kinases. Circulation Research. 80: 607-16. PMID 9130441 DOI: 10.1161/01.Res.80.5.607  0.436
1997 Wiesner TF, Berk BC, Nerem RM. A mathematical model of the cytosolic-free calcium response in endothelial cells to fluid shear stress Proceedings of the National Academy of Sciences of the United States of America. 94: 3726-3731. PMID 9108045 DOI: 10.1073/Pnas.94.8.3726  0.309
1997 Liao DF, Monia B, Dean N, Berk BC. Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells. The Journal of Biological Chemistry. 272: 6146-50. PMID 9045626 DOI: 10.1074/Jbc.272.10.6146  0.482
1997 Kusuhara M, Chait A, Cader A, Berk BC. Oxidized LDL stimulates mitogen-activated protein kinases in smooth muscle cells and macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 141-8. PMID 9012649 DOI: 10.1161/01.Atv.17.1.141  0.39
1997 Takahashi M, Berk BC. Mitogen-activated protein kinase (ERK1/2) activation by shear stress and adhesion in endothelial cells. Essential role for a herbimycin-sensitive kinase. The Journal of Clinical Investigation. 98: 2623-31. PMID 8958227 DOI: 10.1172/Jci119083  0.48
1996 Liao DF, Duff JL, Daum G, Pelech SL, Berk BC. Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells, Role of Raf. Circulation Research. 79: 1007-14. PMID 8888693 DOI: 10.1161/01.Res.79.5.1007  0.421
1996 Corson MA, James NL, Latta SE, Nerem RM, Berk BC, Harrison DG. Phosphorylation of endothelial nitric oxide synthase in response to fluid shear stress. Circulation Research. 79: 984-91. PMID 8888690 DOI: 10.1161/01.Res.79.5.984  0.396
1996 Ishida T, Peterson TE, Kovach NL, Berk BC. MAP kinase activation by flow in endothelial cells. Role of beta 1 integrins and tyrosine kinases. Circulation Research. 79: 310-6. PMID 8756009 DOI: 10.1161/01.Res.79.2.310  0.458
1996 Berk BC, Corson MA, Peterson TE, Tseng H. Protein kinases as mediators of fluid shear stress stimulated signal transduction in endothelial cells: a hypothesis for calcium-dependent and calcium-independent events activated by flow. Journal of Biomechanics. 28: 1439-50. PMID 8666584 DOI: 10.1016/0021-9290(95)00092-5  0.427
1996 Abe J, Kusuhara M, Ulevitch RJ, Berk BC, Lee JD. Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase. The Journal of Biological Chemistry. 271: 16586-90. PMID 8663194 DOI: 10.1074/Jbc.271.28.16586  0.47
1996 Lucchesi PA, Bell JM, Willis LS, Byron KL, Corson MA, Berk BC. Ca(2+)-dependent mitogen-activated protein kinase activation in spontaneously hypertensive rat vascular smooth muscle defines a hypertensive signal transduction phenotype. Circulation Research. 78: 962-70. PMID 8635246 DOI: 10.1161/01.Res.78.6.962  0.334
1995 Marrero MB, Schieffer B, Paxton WG, Duff JL, Berk BC, Bernstein KE. The role of tyrosine phosphorylation in angiotensin II-mediated intracellular signalling. Cardiovascular Research. 30: 530-6. PMID 8575001 DOI: 10.1016/S0008-6363(95)00094-1  0.387
1995 Duff JL, Marrero MB, Paxton WG, Schieffer B, Bernstein KE, Berk BC. Angiotensin II signal transduction and the mitogen-activated protein kinase pathway. Cardiovascular Research. 30: 511-7. PMID 8574999 DOI: 10.1016/S0008-6363(95)00088-7  0.459
1995 Fishel RS, Eisenberg S, Shai SY, Redden RA, Bernstein KE, Berk BC. Glucocorticoids induce angiotensin-converting enzyme expression in vascular smooth muscle Hypertension. 25: 343-349. PMID 7875759 DOI: 10.1161/01.Hyp.25.3.343  0.358
1995 Fishel RS, Thourani V, Eisenberg SJ, Shai SY, Corson MA, Nabel EG, Bernstein KE, Berk BC. Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells: Possible mediator of the response to vascular injury Journal of Clinical Investigation. 95: 377-387. PMID 7814638 DOI: 10.1172/Jci117666  0.365
1995 Marrero MB, Schieffer B, Paxton WG, Heerdt L, Berk BC, Delafontaine P, Bernstein KE. Direct stimulation of Jak/STAT pathway by the angiotensin II AT1 receptor Nature. 375: 247-250. PMID 7746328 DOI: 10.1038/375247A0  0.414
1995 Lucchesi PA, Berk BC. Regulation of sodium-hydrogen exchange in vascular smooth muscle Cardiovascular Research. 29: 172-177. PMID 7736491 DOI: 10.1016/S0008-6363(96)88566-X  0.429
1995 Duff JL, Monia BP, Berk BC. Mitogen-activated protein (MAP) kinase is regulated by the MAP kinase phosphatase (MKP-1) in vascular smooth muscle cells. Effect of actinomycin D and antisense oligonucleotides. The Journal of Biological Chemistry. 270: 7161-6. PMID 7706254 DOI: 10.1074/Jbc.270.13.7161  0.416
1995 Helmlinger G, Berk BC, Nerem RM. Calcium responses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ American Journal of Physiology - Cell Physiology. 269. PMID 7653519 DOI: 10.1152/Ajpcell.1995.269.2.C367  0.329
1995 Ishida M, Marrero MB, Schieffer B, Ishida T, Bernstein KE, Berk BC. Angiotensin II activates pp60c-src in vascular smooth muscle cells Circulation Research. 77: 1053-1059. PMID 7586216 DOI: 10.1161/01.Res.77.6.1053  0.444
1995 Tseng H, Peterson TE, Berk BC. Fluid shear stress stimulates mitogen-activated protein kinase in endothelial cells. Circulation Research. 77: 869-78. PMID 7554140 DOI: 10.1161/01.Res.77.5.869  0.481
1995 Baas AS, Berk BC. Differential activation of mitogen-activated protein kinases by H2O2 and O2- in vascular smooth muscle cells. Circulation Research. 77: 29-36. PMID 7540516 DOI: 10.1161/01.Res.77.1.29  0.458
1995 Kusuhara M, Wang S, Chait A, Berk B. 901-122 Oxidized LDL Stimulates Mitogen-activated Protein Kinases in Smooth Muscle Cells and Macrophages Journal of the American College of Cardiology. 25: 34A. DOI: 10.1016/0735-1097(95)91599-S  0.423
1994 Lucchesi PA, DeRoux N, Berk BC. Na+-H+ exchanger expression in vascular smooth muscle of spontaneously hypertensive and Wistar-Kyoto rats Hypertension. 24: 734-738. PMID 7995631 DOI: 10.1161/01.Hyp.24.6.734  0.366
1994 Paxton WG, Marrero MB, Klein JD, Delafontaine P, Berk BC, Bernstein KE. The Angiotensin II AT1 Receptor Is Tyrosine and Serine Phosphorylated and can Serve as a Substrate for the SRC Family of Tyrosine Kinases Biochemical and Biophysical Research Communications. 200: 260-267. PMID 7513159 DOI: 10.1006/Bbrc.1994.1443  0.407
1993 Rao GN, Lasségue B, Griendling KK, Alexander RW, Berk BC. Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C. Nucleic Acids Research. 21: 1259-63. PMID 8464709 DOI: 10.1093/Nar/21.5.1259  0.318
1993 Berk BC, Rao GN. Angiotensin II-induced vascular smooth muscle cell hypertrophy: PDGF A-chain mediates the increase in cell size Journal of Cellular Physiology. 154: 368-380. PMID 8425918 DOI: 10.1002/Jcp.1041540221  0.397
1993 Mitsuka M, Nagae M, Berk BC. Na(+)-H+ exchange inhibitors decrease neointimal formation after rat carotid injury. Effects on smooth muscle cell migration and proliferation. Circulation Research. 73: 269-75. PMID 8392448 DOI: 10.1161/01.Res.73.2.269  0.384
1993 Rao GN, Sardet C, Pouysségur J, Berk BC. Phosphorylation of Na(+)-H+ antiporter is not stimulated by phorbol ester and acidification in granulocytic HL-60 cells. The American Journal of Physiology. 264: C1278-84. PMID 8388633 DOI: 10.1152/Ajpcell.1993.264.5.C1278  0.348
1993 Mitsumata M, Fishel RS, Nerem RM, Alexander RW, Berk BC. Fluid shear stress stimulates platelet-derived growth factor expression in endothelial cells American Journal of Physiology - Heart and Circulatory Physiology. 265. PMID 8342646 DOI: 10.1152/Ajpheart.1993.265.1.H3  0.44
1993 Bernstein KE, Berk BC. The biology of angiotensin II receptors American Journal of Kidney Diseases. 22: 745-754. PMID 8238023 DOI: 10.1016/S0272-6386(12)80441-0  0.331
1993 MITSUMATA M, YOSHIDA Y, NEREM RM, ALEXANDER RW, BERK BC. Effects of Shear Stress on Endothelial Cell Functions The Journal of Japan Atherosclerosis Society. 21: 473-477. DOI: 10.5551/Jat1973.21.6-7_473  0.343
1992 Taubman MB, Rollins BJ, Poon M, Marmur J, Green RS, Berk BC, Nadal-Ginard B. JE mRNA accumulates rapidly in aortic injury and in platelet-derived growth factor-stimulated vascular smooth muscle cells. Circulation Research. 70: 314-25. PMID 1735132 DOI: 10.1161/01.Res.70.2.314  0.403
1992 Geiger RV, Berk BC, Alexander RW, Nerem RM. Flow-induced calcium transients in single endothelial cells: Spatial and temporal analysis American Journal of Physiology - Cell Physiology. 262. PMID 1616008 DOI: 10.1152/Ajpcell.1992.262.6.C1411  0.336
1992 Corson MA, Alexander RW, Berk BC. 5-HT2 receptor mRNA is overexpressed in cultured rat aortic smooth muscle cells relative to normal aorta. The American Journal of Physiology. 262: C309-15. PMID 1539623 DOI: 10.1152/Ajpcell.1992.262.2.C309  0.317
1992 Duff JL, Berk BC, Corson MA. Angiotensin II stimulates the pp44 and pp42 mitogen-activated protein kinases in cultured rat aortic smooth muscle cells. Biochemical and Biophysical Research Communications. 188: 257-64. PMID 1384482 DOI: 10.1016/0006-291X(92)92378-B  0.434
1992 Krug LM, Berk BC. Na+, K(+)-adenosine triphosphatase regulation in hypertrophied vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 20: 144-50. PMID 1322364 DOI: 10.1161/01.Hyp.20.2.144  0.324
1992 Berk BC, Corson MA. Autocrine and paracrine growth mechanisms in vascular smooth muscle Current Opinion in Cardiology. 7: 739-744. DOI: 10.1097/00001573-199210000-00002  0.319
1991 Berk BC, Gordon JB, Alexander RW. Pharmacologic roles of heparin and glucocorticoids to prevent restenosis after coronary angioplasty. Journal of the American College of Cardiology. 17: 111B-117B. PMID 2016469 DOI: 10.1016/0735-1097(91)90946-7  0.305
1991 Berk BC, Taubman MB, Griendling KK, Cragoe EJ, Fenton JW, Brock TA. Thrombin-stimulated events in cultured vascular smooth-muscle cells. The Biochemical Journal. 274: 799-805. PMID 2012607 DOI: 10.1042/Bj2740799  0.377
1991 Mitsuka M, Berk BC. Long-term regulation of Na(+)-H+ exchange in vascular smooth muscle cells: role of protein kinase C. The American Journal of Physiology. 260: C562-9. PMID 1848402 DOI: 10.1152/Ajpcell.1991.260.3.C562  0.388
1990 Griendling KK, Berk BC, Socorro L, Tsuda T, Delafontaine P, Alexander RW. Secondary signalling mechanisms in angiotensin II-stimulated vascular smooth muscle cells. Clinical and Experimental Pharmacology & Physiology. 15: 105-12. PMID 3078271 DOI: 10.1111/J.1440-1681.1988.Tb01051.X  0.449
1990 Rao GN, Berk BC. Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression Circulation Research. 70: 593-599. PMID 1371430 DOI: 10.1161/01.Res.70.3.593  0.42
1990 Shai SY, Fishel RS, Martin BM, Berk BC, Bernstein KE. Bovine angiotensin converting enzyme cDNA cloning and regulation: Increased expression during endothelial cell growth arrest Circulation Research. 70: 1274-1281. PMID 1315639 DOI: 10.1161/01.Res.70.6.1274  0.359
1989 Griendling KK, Tsuda T, Berk BC, Alexander RW. Angiotensin II stimulation of vascular smooth muscle cells. Secondary signalling mechanisms. American Journal of Hypertension. 2: 659-65. PMID 2673302 DOI: 10.1093/ajh/2.8.659  0.337
1989 Berk BC, Vallega G, Muslin AJ, Gordon HM, Canessa M, Alexander RW. Spontaneously hypertensive rat vascular smooth muscle cells in culture exhibit increased growth and Na+/H+ exchange. The Journal of Clinical Investigation. 83: 822-9. PMID 2537850 DOI: 10.1172/Jci113964  0.636
1989 Berk BC, Vekshtein V, Gordon HM, Tsuda T. Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979). 13: 305-14. PMID 2466788 DOI: 10.1161/01.Hyp.13.4.305  0.406
1988 Berk BC, Vallega G, Griendling KK, Gordon JB, Cragoe EJ, Canessa M, Alexander RW. Effects of glucocorticoids on Na+/H+ exchange and growth in cultured vascular smooth muscle cells. Journal of Cellular Physiology. 137: 391-401. PMID 2461379 DOI: 10.1002/Jcp.1041370302  0.347
1988 Berk BC, Canessa M, Vallega G, Alexander RW. Agonist-Mediated Changes in Intracellular pH Journal of Cardiovascular Pharmacology. 12: 104-114. DOI: 10.1097/00005344-198800125-00019  0.371
1987 Danthuluri NR, Berk BC, Brock TA, Cragoe EJ, Deth RC. Protein kinase C-mediated intracellular alkalinization in rat and rabbit aortic smooth muscle cells. European Journal of Pharmacology. 141: 503-6. PMID 3666043 DOI: 10.1016/0014-2999(87)90574-7  0.423
1987 Griendling KK, Berk BC, Ganz P, Gimbrone MA, Alexander RW. Angiotensin II stimulation of vascular smooth muscle phosphoinositide metabolism. State of the art lecture. Hypertension (Dallas, Tex. : 1979). 9: III181-5. PMID 3036701 DOI: 10.1161/01.Hyp.9.6_Pt_2.Iii181  0.416
1987 Berk BC, Nabel EG, Griendling KK, Smith TW, Alexander RW. Vasoconstrictor-mediated ionic events associated with sustained contractile responses in cultured vascular smooth muscle cells Journal of Molecular and Cellular Cardiology. 19: S5. DOI: 10.1016/S0022-2828(87)80640-5  0.337
1986 Berk BC, Alexander RW, Brock TA, Gimbrone MA, Webb RC. Vasoconstriction: a new activity for platelet-derived growth factor. Science (New York, N.Y.). 232: 87-90. PMID 3485309 DOI: 10.1126/Science.3485309  0.374
1985 Berk BC, Brock TA, Webb RC, Taubman MB, Atkinson WJ, Gimbrone MA, Alexander RW. Epidermal growth factor, a vascular smooth muscle mitogen, induces rat aortic contraction. The Journal of Clinical Investigation. 75: 1083-6. PMID 3872314 DOI: 10.1172/Jci111772  0.357
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