Denis deBlois - Publications

Affiliations: 
Université de Montréal, Montréal, Canada 
Area:
Pharmacology, Cell Biology, Pathology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Deng AY, Huot-Marchard JÉ, deBlois D, Thorin E, Chauvet C, Menard A. Functional Dosage of Muscarinic Cholinergic Receptor 3 Signalling, Not the Gene Dose, Determines Its Hypertension Pathogenesis. The Canadian Journal of Cardiology. PMID 30955929 DOI: 10.1016/J.Cjca.2018.12.029  0.318
2018 Deng AY, deBlois D, Laporte SA, Gelinas D, Tardif JC, Thorin E, Shi Y, Raignault A, Ménard A. Novel Pathogenesis of Hypertension and Diastolic Dysfunction Caused by M3R (Muscarinic Cholinergic 3 Receptor) Signaling. Hypertension (Dallas, Tex. : 1979). 72: 755-764. PMID 30354759 DOI: 10.1161/Hypertensionaha.118.11385  0.374
2017 McCormick B, Hannan J, Huot-Marchand J, Carroll C, Carrier S, deBlois D, Hale T. 058 Bradykinin B1 Receptor Antagonism Prevents Angiotensin II-Induced Erectile Dysfunction The Journal of Sexual Medicine. 14: e29. DOI: 10.1016/J.Jsxm.2016.12.072  0.344
2014 Huyard F, Yzydorczyk C, Castro MM, Cloutier A, Bertagnolli M, Sartelet H, Germain N, Comte B, Schulz R, DeBlois D, Nuyt AM. Remodeling of aorta extracellular matrix as a result of transient high oxygen exposure in newborn rats: Implication for arterial rigidity and hypertension risk Plos One. 9. PMID 24743169 DOI: 10.1371/Journal.Pone.0092287  0.39
2014 Brodeur MR, Bouvet C, Bouchard S, Moreau S, Leblond J, DeBlois D, Moreau P. Reduction of advanced-glycation end products levels and inhibition of rage signaling decreases rat vascular calcification induced by diabetes Plos One. 9. PMID 24465790 DOI: 10.1371/Journal.Pone.0085922  0.337
2014 Bertagnolli M, Huyard F, Cloutier A, Anstey Z, Huot-Marchand JÉ, Fallaha C, Paradis P, Schiffrin EL, Deblois D, Nuyt AM. Transient neonatal high oxygen exposure leads to early adult cardiac dysfunction, remodeling, and activation of the renin-angiotensin system. Hypertension. 63: 143-50. PMID 24166752 DOI: 10.1161/Hypertensionaha.113.01760  0.416
2013 Der Sarkissian S, Tea BS, Touyz RM, Deblois D, Hale TM. Role of angiotensin II type 2 receptor during regression of cardiac hypertrophy in spontaneously hypertensive rats Journal of the American Society of Hypertension. 7: 118-127. PMID 23414835 DOI: 10.1016/J.Jash.2013.01.002  0.778
2012 Hale TM, Robertson SJ, Burns KD, DeBlois D. Short-term ACE inhibition confers long-term protection against target organ damage Hypertension Research. 35: 604-610. PMID 22318205 DOI: 10.1038/Hr.2012.2  0.398
2011 El Midaoui A, Lungu C, Wang H, Wu L, Robillard C, Deblois D, Couture R. Impact of α-lipoic acid on liver peroxisome proliferator-activated receptor-α, vascular remodeling, and oxidative stress in insulin-resistant rats. Canadian Journal of Physiology and Pharmacology. 89: 743-51. PMID 21919742 DOI: 10.1139/Y11-072  0.313
2011 Doyon M, Hale TM, Huot-Marchand JE, Wu R, de Champlain J, DeBlois D. Does atorvastatin induce aortic smooth muscle cell apoptosis in vivo? Vascular Pharmacology. 54: 5-12. PMID 20951229 DOI: 10.1016/J.Vph.2010.10.001  0.538
2010 Marceau F, deBlois D, Petitclerc E, Levesque L, Drapeau G, Audet R, Godin D, Larrivée JF, Houle S, Sabourin T, Fortin JP, Morissette G, Gera L, Bawolak MT, Koumbadinga GA, et al. Vascular smooth muscle contractility assays for inflammatory and immunological mediators. International Immunopharmacology. 10: 1344-53. PMID 20831918 DOI: 10.1016/J.Intimp.2010.08.016  0.338
2009 Lemay J, Hale TM, deBlois D. Neointimal-specific induction of apoptosis by losartan results in regression of vascular lesion in rat aorta European Journal of Pharmacology. 618: 45-51. PMID 19619526 DOI: 10.1016/J.Ejphar.2009.07.014  0.527
2009 El-Helou V, Proulx C, Béguin P, Assimakopoulos J, Gosselin H, Clement R, Villeneuve L, Huot-Marchand JE, Deblois D, Lajoie C, Calderone A. The cardiac neural stem cell phenotype is compromised in streptozotocin-induced diabetic cardiomyopathy. Journal of Cellular Physiology. 220: 440-9. PMID 19388005 DOI: 10.1002/Jcp.21785  0.338
2009 Pilon M, Wu R, Huot-Marchand JE, deBlois D, Champlain Jd, Couture R. Effect of chronic inhibition of nitric oxide on hypertension, insulin resistance, and cardiovascular remodeling in glucose-fed rats. Journal of Cardiovascular Pharmacology. 53: 405-13. PMID 19333132 DOI: 10.1097/Fjc.0B013E3181A1D88A  0.386
2009 Hale TM, Hannan JL, Carrier S, Deblois D, Adams MA. Targeting vascular structure for the treatment of sexual dysfunction Journal of Sexual Medicine. 6: 210-220. PMID 19207270 DOI: 10.1111/J.1743-6109.2008.01174.X  0.336
2008 Wang X, Adams LD, Pabón LM, Mahoney WM, Beaudry D, Gunaje J, Geary RL, Deblois D, Schwartz SM. RGS5, RGS4, and RGS2 expression and aortic contractibility are dynamically co-regulated during aortic banding-induced hypertrophy. Journal of Molecular and Cellular Cardiology. 44: 539-50. PMID 18207159 DOI: 10.1016/J.Yjmcc.2007.11.019  0.41
2008 Pilon MM, Wu R, Huot-Marchand J, DeBlois D, De Champlain J, Couture R. Chronic Inhibition of Nitric Oxide Synthase Worsen Hypertension and Insulin Resistance, but not Cardiovascular Remodeling, in Glucose-Fed Rats. Canadian Journal of Diabetes. 32: 332. DOI: 10.1016/S1499-2671(08)24133-X  0.321
2008 Mampouma F, Hale TM, Carrier S, deBlois D. EARLY INDUCTION OF ERECTILE DYSFUNCTION BY ANGIOTENSIN II IN RAT Journal of Urology. 179: 279-280. DOI: 10.1016/S0022-5347(08)60813-7  0.382
2007 Paquette PA, Duguay D, El-Ayoubi R, Menaouar A, Danalache B, Gutkowska J, DeBlois D, Mukaddam-Daher S. Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation. British Journal of Pharmacology. 153: 459-67. PMID 18059325 DOI: 10.1038/Sj.Bjp.0707588  0.347
2007 Duguay D, deBlois D. Differential regulation of Akt, caspases and MAP kinases underlies smooth muscle cell apoptosis during aortic remodelling in SHR treated with amlodipine. British Journal of Pharmacology. 151: 1315-23. PMID 17592516 DOI: 10.1038/Sj.Bjp.0707334  0.483
2007 Duguay D, Pesant S, Deschepper CF, deBlois D. Fibroblast apoptosis precedes cardiomyocyte mass reduction during left ventricular remodeling in hypertensive rats treated with amlodipine. Journal of Hypertension. 25: 1291-9. PMID 17563544 DOI: 10.1097/Hjh.0B013E3280E126D5  0.483
2005 Deblois D, Tea BS, Beaudry D, Hamet P. Regulation of therapeutic apoptosis: a potential target in controlling hypertensive organ damage. Canadian Journal of Physiology and Pharmacology. 83: 29-41. PMID 15759048 DOI: 10.1139/Y05-001  0.48
2005 Dutil J, Eliopoulos V, Marchand EL, Devlin AM, Tremblay J, Prithiviraj K, Hamet P, Migneault A, DeBlois D, Deng AY. A quantitative trait locus for aortic smooth muscle cell number acting independently of blood pressure: Implicating the angiotensin receptor AT1B gene as a candidate Physiological Genomics. 21: 362-369. PMID 15741507 DOI: 10.1152/Physiolgenomics.00063.2004  0.749
2005 Bouvet C, Gilbert LA, Girardot D, deBlois D, Moreau P. Different involvement of extracellular matrix components in small and large arteries during chronic NO synthase inhibition. Hypertension. 45: 432-7. PMID 15655118 DOI: 10.1161/01.Hyp.0000154680.44184.01  0.321
2004 Gennaro G, Ménard C, Michaud SE, Deblois D, Rivard A. Inhibition of vascular smooth muscle cell proliferation and neointimal formation in injured arteries by a novel, oral mitogen-activated protein kinase/extracellular signal-regulated kinase inhibitor. Circulation. 110: 3367-71. PMID 15520324 DOI: 10.1161/01.Cir.0000147773.86866.Cd  0.343
2004 Girardot D, Jover B, Moles JP, Deblois D, Moreau P. Chronic nitric oxide synthase inhibition prevents new coronary capillary generation. Journal of Cardiovascular Pharmacology. 44: 322-8. PMID 15475829 DOI: 10.1097/01.Fjc.0000134819.00517.E0  0.331
2004 Benderdour M, Charron G, Comte B, Ayoub R, Beaudry D, Foisy S, Deblois D, Des Rosiers C. Decreased cardiac mitochondrial NADP+-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development. American Journal of Physiology. Heart and Circulatory Physiology. 287: H2122-31. PMID 15271667 DOI: 10.1152/Ajpheart.00378.2004  0.384
2004 Der Sarkissian S, Marchand EL, Duguay D, deBlois D. Synergistic interaction between enalapril, L-arginine and tetrahydrobiopterin in smooth muscle cell apoptosis and aortic remodeling induction in SHR. British Journal of Pharmacology. 142: 912-8. PMID 15197102 DOI: 10.1038/Sj.Bjp.0705830  0.732
2004 Duguay D, Der Sarkissian S, Kouz R, Ongali B, Couture R, deBlois D. Kinin B2 receptor is not involved in enalapril-induced apoptosis and regression of hypertrophy in spontaneously hypertensive rat aorta: possible role of B1 receptor. British Journal of Pharmacology. 141: 728-36. PMID 14744816 DOI: 10.1038/Sj.Bjp.0705642  0.781
2004 Duguay D, Kouz R, Ongali B, Couture R, deBlois D. KINETICS OF ENALAPRIL-INDUCED SMOOTH MUSCLE CELL APOPTOSIS AND REGRESSION OF AORTIC HYPERTROPHY CORRELATE WITH KININ B1 RECEPTOR UP-REGULATION IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR) Cardiovascular Pathology. 13: 84. DOI: 10.1016/J.Carpath.2004.03.250  0.518
2004 Hamet P, Orlov SN, deBlois D, Sun Y, Kren V, Tremblay J. Angiotensin as a Cytokine Implicated in Accelerated Cellular Turnover Handbook of Experimental Pharmacology. 163: 71-98. DOI: 10.1007/978-3-642-18495-6_3  0.425
2003 Girardot D, Demeilliers B, deBlois D, Moreau P. ERK1/2-mediated vasoconstriction normalizes wall stress in small mesenteric arteries during NOS inhibition in vivo. Journal of Cardiovascular Pharmacology. 42: 339-47. PMID 12960678 DOI: 10.1097/00005344-200309000-00004  0.344
2003 Benderdour M, Charron G, DeBlois D, Comte B, Des Rosiers C. Cardiac mitochondrial NADP+-isocitrate dehydrogenase is inactivated through 4-hydroxynonenal adduct formation: an event that precedes hypertrophy development. The Journal of Biological Chemistry. 278: 45154-9. PMID 12960146 DOI: 10.1074/Jbc.M306285200  0.348
2003 Orlov SN, Pchejetski DV, Sarkissian SD, Adarichev V, Taurin S, Pshezhetsky AV, Tremblay J, Maximov GV, deBlois D, Bennett MR, Hamet P. [3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein. Apoptosis : An International Journal On Programmed Cell Death. 8: 199-208. PMID 12766480 DOI: 10.1023/A:1022931028235  0.42
2003 Marchand EL, Der Sarkissian S, Hamet P, deBlois D. Caspase-dependent cell death mediates the early phase of aortic hypertrophy regression in losartan-treated spontaneously hypertensive rats. Circulation Research. 92: 777-84. PMID 12623880 DOI: 10.1161/01.Res.0000065619.36118.20  0.75
2003 Der Sarkissian S, Marchand EL, Duguay D, Hamet P, deBlois D. Reversal of interstitial fibroblast hyperplasia via apoptosis in hypertensive rat heart with valsartan or enalapril. Cardiovascular Research. 57: 775-83. PMID 12618239 DOI: 10.1016/S0008-6363(02)00789-7  0.737
2003 Pchejetski D, Taurin S, Der Sarkissian S, Lopina OD, Pshezhetsky AV, Tremblay J, deBlois D, Hamet P, Orlov SN. Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+]i/[K+]i ratio. Biochemical and Biophysical Research Communications. 301: 735-44. PMID 12565842 DOI: 10.1016/S0006-291X(02)03002-4  0.712
2003 Orlov SN, Pchejetski DV, Sarkissian SD, Adarichev V, Taurin S, Pshezhetsky AV, Tremblay J, Maximov GV, DeBlois D, Bennett MR, Hamet P. [3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein Apoptosis. 8: 199-208. DOI: 10.1023/A:1022931028235  0.302
2002 Tremblay J, Chen H, Peng J, Kunes J, Vu MD, Der Sarkissian S, deBlois D, Bolton AE, Gaboury L, Marshansky V, Gouadon E, Hamet P. Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy. Transplantation. 74: 1425-33. PMID 12451244 DOI: 10.1097/00007890-200211270-00015  0.713
2002 Chen LQ, Hu CY, Der Sarkissian S, Ferraro P, Pera M, deBlois D, Gaboury L, Duranceau AC. Apoptosis in Barrett's oesophagus following antireflux surgery. The British Journal of Surgery. 89: 1444-9. PMID 12390390 DOI: 10.1046/J.1365-2168.2002.02229.X  0.307
2002 Lemay J, Hamet P, deBlois D. Losartan-induced apoptosis as a novel mechanism for the prevention of vascular lesion formation after injury. Journal of the Renin-Angiotensin-Aldosterone System : Jraas. 1: 46-50. PMID 11967799 DOI: 10.3317/Jraas.2000.010  0.503
2002 deBlois D, Orlov SN, Hamet P. Apoptosis in cardiovascular remodeling--effect of medication. Cardiovascular Drugs and Therapy. 15: 539-45. PMID 11916363 DOI: 10.1023/A:1013723922582  0.436
2002 Orlov SN, Tremblay J, Deblois D, Hamet P. Genetics of programmed cell death and proliferation. Seminars in Nephrology. 22: 161-71. PMID 11891510 DOI: 10.1053/Snep.2002.2002.30434  0.427
2002 Martens FM, Demeilliers B, Girardot D, Daigle C, Dao HH, deBlois D, Moreau P. Vessel-specific stimulation of protein synthesis by nitric oxide synthase inhibition: role of extracellular signal-regulated kinases 1/2. Hypertension. 39: 16-21. PMID 11799072 DOI: 10.1161/Hy0102.099025  0.331
2001 Dao HH, Lemay J, de Champlain J, deBlois D, Moreau P. Norepinephrine-induced aortic hyperplasia and extracellular matrix deposition are endothelin-dependent. Journal of Hypertension. 19: 1965-73. PMID 11677361 DOI: 10.1097/00004872-200111000-00006  0.344
2001 Thorin-Trescases N, deBlois D, Hamet P. Evidence of an altered in vivo vascular cell turnover in spontaneously hypertensive rats and its modulation by long-term antihypertensive treatment. Journal of Cardiovascular Pharmacology. 38: 764-74. PMID 11602823 DOI: 10.1097/00005344-200111000-00013  0.428
2001 Lemay J, Tea BS, Hamet P, deBlois D. Regression of neointimal lesions in the carotid artery of nifedipine-treated SHR and WKY rats: possible role of apoptosis. Journal of Vascular Research. 38: 462-70. PMID 11561148 DOI: 10.1159/000051079  0.522
2001 Thorin-Trescases N, Orlov SN, Taurin S, Dulin NO, Allen BG, deBlois D, Tremblay J, Pshezhetsky AV, Hamet P. Antiproliferative effect of brief exposure to cholera toxin in vascular smooth muscle cells: role of cAMP and protein kinase A. Canadian Journal of Physiology and Pharmacology. 79: 471-80. PMID 11430584 DOI: 10.1139/Y01-017  0.306
2001 Hamet P, Thorin-Trescases N, Moreau P, Dumas P, Tea BS, deBlois D, Kren V, Pravenec M, Kunes J, Sun Y, Tremblay J. Workshop: excess growth and apoptosis: is hypertension a case of accelerated aging of cardiovascular cells? Hypertension. 37: 760-6. PMID 11230370 DOI: 10.1161/01.Hyp.37.2.760  0.446
2001 deBlois D, Horlick RA. Endotoxin sensitization to kinin B(1) receptor agonist in a non-human primate model: haemodynamic and pro-inflammatory effects. British Journal of Pharmacology. 132: 327-35. PMID 11156593 DOI: 10.1038/Sj.Bjp.0703748  0.333
2001 Sarkissian SD, Hamet P, deBlois D. Angiotensin II blockade induces mesothelial cell apoptosis in the epicardium Journal of Molecular and Cellular Cardiology. 33: A105. DOI: 10.1016/S0022-2828(01)90418-3  0.434
2001 Marchand E, Der Sarkissian S, Hamet P, deBlois D. Caspase-dependent cell death of non-carmyocytes in losartan-treated SHR Journal of Molecular and Cellular Cardiology. 33: A73. DOI: 10.1016/S0022-2828(01)90288-3  0.758
2001 Beaudry D, Hemet P, deBlois D. Valsartan prevents aortic hyperplasia induced by chronic pressure-overload Journal of Molecular and Cellular Cardiology. 33: A10. DOI: 10.1016/S0022-2828(01)90036-7  0.349
2000 Tea BS, Der Sarkissian S, Touyz RM, Hamet P, deBlois D. Proapoptotic and growth-inhibitory role of angiotensin II type 2 receptor in vascular smooth muscle cells of spontaneously hypertensive rats in vivo. Hypertension. 35: 1069-73. PMID 10818066 DOI: 10.1161/01.Hyp.35.5.1069  0.495
2000 Lemay J, Hou Y, Tremblay J, deBlois D. Angiotensin I-converting enzyme activity and vascular sensitivity to angiotensin I in rat injured carotid artery. European Journal of Pharmacology. 394: 301-9. PMID 10771296 DOI: 10.1016/S0014-2999(00)00071-6  0.384
2000 Deng AY, Dutil J, deBlois D, Tremblay J. Mapping of Two Quantitative Trait Loci (QTL) for Blood Pressure (BP) on Rat Chromosome (CHR.) 2 Using Congenic Strains by Telemetry Hypertension. 36: 718-719. DOI: 10.1161/01.Hyp.36.Suppl_1.718-D  0.303
1999 Tea BS, Dam TV, Moreau P, Hamet P, deBlois D. Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats. Temporal regulation and spatial heterogeneity. Hypertension. 34: 229-35. PMID 10454446 DOI: 10.1161/01.Hyp.34.2.229  0.468
1998 Silver PJ, Moreau JP, Denholm E, Lin YQ, Nguyen L, Bennett C, Recktenwald A, DeBlois D, Baker S, Ranger S. Heparinase III limits rat arterial smooth muscle cell proliferation in vitro and in vivo. European Journal of Pharmacology. 351: 79-83. PMID 9698208 DOI: 10.1016/S0014-2999(98)00293-3  0.402
1997 deBlois D, Tea BS, Than VD, Tremblay J, Hamet P. Smooth muscle apoptosis during vascular regression in spontaneously hypertensive rats. Hypertension. 29: 340-9. PMID 9039125 DOI: 10.1161/01.Hyp.29.1.340  0.496
1996 Hamet P, deBlois D, Dam T-, Richard L, Teiger E, Tea B-, Orlov SN, Tremblay J. Apoptosis and vascular wall remodeling in hypertension Canadian Journal of Physiology and Pharmacology. 74: 850-861. DOI: 10.1139/Y96-076  0.492
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