| Year |
Citation |
Score |
| 2016 |
Kumar A, Zhang J, Tallaksen-Greene S, Crowley MR, Crossman DK, Morton AJ, van Groen T, Kadish I, Albin RL, Lesort M, Detloff PJ. Allelic Series of Huntington's Disease Knock-in Mice Reveals Expression Discorrelates. Human Molecular Genetics. PMID 26908599 DOI: 10.1093/Hmg/Ddw040 |
0.372 |
|
| 2014 |
Dougherty SE, Hollimon JJ, McMeekin LJ, Bohannon AS, West AB, Lesort M, Hablitz JJ, Cowell RM. Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells. Neurobiology of Disease. 62: 160-71. PMID 24121117 DOI: 10.1016/J.Nbd.2013.10.002 |
0.39 |
|
| 2013 |
Lee W, Reyes RC, Gottipati MK, Lewis K, Lesort M, Parpura V, Gray M. Enhanced Ca(2+)-dependent glutamate release from astrocytes of the BACHD Huntington's disease mouse model. Neurobiology of Disease. 58: 192-9. PMID 23756199 DOI: 10.1016/J.Nbd.2013.06.002 |
0.381 |
|
| 2013 |
Dougherty SE, Reeves JL, Lesort M, Detloff PJ, Cowell RM. Purkinje cell dysfunction and loss in a knock-in mouse model of Huntington disease. Experimental Neurology. 240: 96-102. PMID 23195593 DOI: 10.1016/J.Expneurol.2012.11.015 |
0.42 |
|
| 2012 |
Kumar A, Kneynsberg A, Tucholski J, Perry G, van Groen T, Detloff PJ, Lesort M. Tissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's disease. Experimental Neurology. 237: 78-89. PMID 22698685 DOI: 10.1016/J.Expneurol.2012.05.015 |
0.435 |
|
| 2012 |
Dougherty SE, Reeves JL, Lucas EK, Gamble KL, Lesort M, Cowell RM. Disruption of Purkinje cell function prior to huntingtin accumulation and cell loss in an animal model of Huntington disease. Experimental Neurology. 236: 171-8. PMID 22579526 DOI: 10.1016/J.Expneurol.2012.04.015 |
0.406 |
|
| 2011 |
Slone SR, Lesort M, Yacoubian TA. 14-3-3theta protects against neurotoxicity in a cellular Parkinson's disease model through inhibition of the apoptotic factor Bax. Plos One. 6: e21720. PMID 21799745 DOI: 10.1371/Journal.Pone.0021720 |
0.42 |
|
| 2011 |
Reyes RC, Perry G, Lesort M, Parpura V. Immunophilin deficiency augments Ca2+-dependent glutamate release from mouse cortical astrocytes. Cell Calcium. 49: 23-34. PMID 21163525 DOI: 10.1016/J.Ceca.2010.11.005 |
0.364 |
|
| 2011 |
Tower C, Fu L, Gill R, Prichard M, Lesort M, Sztul E. Human cytomegalovirus UL97 kinase prevents the deposition of mutant protein aggregates in cellular models of Huntington's disease and ataxia. Neurobiology of Disease. 41: 11-22. PMID 20732421 DOI: 10.1016/J.Nbd.2010.08.013 |
0.366 |
|
| 2010 |
Heng MY, Duong DK, Albin RL, Tallaksen-Greene SJ, Hunter JM, Lesort MJ, Osmand A, Paulson HL, Detloff PJ. Early autophagic response in a novel knock-in model of Huntington disease. Human Molecular Genetics. 19: 3702-20. PMID 20616151 DOI: 10.1093/Hmg/Ddq285 |
0.328 |
|
| 2010 |
Perry GM, Tallaksen-Greene S, Kumar A, Heng MY, Kneynsberg A, van Groen T, Detloff PJ, Albin RL, Lesort M. Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease. Human Molecular Genetics. 19: 3354-71. PMID 20558522 DOI: 10.1093/Hmg/Ddq247 |
0.469 |
|
| 2007 |
Hunter JM, Lesort M, Johnson GV. Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease. Journal of Neuroscience Research. 85: 1774-88. PMID 17455294 DOI: 10.1002/Jnr.21287 |
0.481 |
|
| 2006 |
Mao Z, Choo YS, Lesort M. Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells. The European Journal of Neuroscience. 23: 1701-10. PMID 16623826 DOI: 10.1111/J.1460-9568.2006.04686.X |
0.661 |
|
| 2005 |
Seong IS, Ivanova E, Lee JM, Choo YS, Fossale E, Anderson M, Gusella JF, Laramie JM, Myers RH, Lesort M, MacDonald ME. HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism. Human Molecular Genetics. 14: 2871-80. PMID 16115812 DOI: 10.1093/Hmg/Ddi319 |
0.661 |
|
| 2005 |
Choo YS, Mao Z, Johnson GV, Lesort M. Increased glutathione levels in cortical and striatal mitochondria of the R6/2 Huntington's disease mouse model. Neuroscience Letters. 386: 63-8. PMID 15993538 DOI: 10.1016/J.Neulet.2005.05.065 |
0.645 |
|
| 2005 |
Hunter JM, Crouse AB, Lesort M, Johnson GV, Detloff PJ. Verification of somatic CAG repeat expansion by pre-PCR fractionation. Journal of Neuroscience Methods. 144: 11-7. PMID 15848234 DOI: 10.1016/J.Jneumeth.2004.10.006 |
0.353 |
|
| 2004 |
Choo YS, Johnson GV, MacDonald M, Detloff PJ, Lesort M. Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release. Human Molecular Genetics. 13: 1407-20. PMID 15163634 DOI: 10.1093/Hmg/Ddh162 |
0.675 |
|
| 2004 |
Ruan Q, Lesort M, MacDonald ME, Johnson GV. Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway. Human Molecular Genetics. 13: 669-81. PMID 14962977 DOI: 10.1093/Hmg/Ddh082 |
0.513 |
|
| 2003 |
Lesort M, Lee M, Tucholski J, Johnson GV. Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders. The Journal of Biological Chemistry. 278: 3825-30. PMID 12458211 DOI: 10.1074/Jbc.M205812200 |
0.397 |
|
| 2002 |
Chun W, Lesort M, Lee M, Johnson GV. Transient osmotic stress facilitates mutant huntingtin aggregation. Neuroreport. 13: 2543-6. PMID 12499864 DOI: 10.1097/00001756-200212200-00032 |
0.352 |
|
| 2002 |
Chun W, Lesort M, Lee M, Johnson GV. Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors. Febs Letters. 515: 61-5. PMID 11943195 DOI: 10.1016/S0014-5793(02)02436-5 |
0.355 |
|
| 2002 |
Lesort M, Chun W, Tucholski J, Johnson GV. Does tissue transglutaminase play a role in Huntington's disease? Neurochemistry International. 40: 37-52. PMID 11738471 DOI: 10.1046/J.1471-4159.81.S1.20_8.X |
0.421 |
|
| 2001 |
Chun W, Lesort M, Tucholski J, Faber PW, MacDonald ME, Ross CA, Johnson GV. Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells. Neurobiology of Disease. 8: 391-404. PMID 11442349 DOI: 10.1006/Nbdi.2001.0390 |
0.421 |
|
| 2001 |
De Sarno P, Lesort M, Bijur GN, Johnson GV, Jope RS. Cholinergic- and stress-induced signaling activities in cells overexpressing wild-type and mutant presenilin-1. Brain Research. 903: 226-30. PMID 11382407 DOI: 10.1016/S0006-8993(01)02428-3 |
0.355 |
|
| 2001 |
Chun W, Lesort M, Tucholski J, Ross CA, Johnson GV. Tissue transglutaminase does not contribute to the formation of mutant huntingtin aggregates. The Journal of Cell Biology. 153: 25-34. PMID 11285271 DOI: 10.1083/Jcb.153.1.25 |
0.392 |
|
| 2001 |
Tucholski J, Lesort M, Johnson GV. Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells. Neuroscience. 102: 481-91. PMID 11166134 DOI: 10.1016/S0306-4522(00)00482-6 |
0.324 |
|
| 2000 |
Lesort M, Tucholski J, Zhang J, Johnson GV. Impaired mitochondrial function results in increased tissue transglutaminase activity in situ. Journal of Neurochemistry. 75: 1951-61. PMID 11032884 DOI: 10.1046/J.1471-4159.2000.0751951.X |
0.456 |
|
| 2000 |
Lesort M, Tucholski J, Miller ML, Johnson GV. Tissue transglutaminase: a possible role in neurodegenerative diseases. Progress in Neurobiology. 61: 439-63. PMID 10748319 DOI: 10.1016/S0301-0082(99)00052-0 |
0.349 |
|
| 1998 |
Lesort M, Attanavanich K, Zhang J, Johnson GV. Distinct nuclear localization and activity of tissue transglutaminase. The Journal of Biological Chemistry. 273: 11991-4. PMID 9575137 DOI: 10.1074/Jbc.273.20.11991 |
0.361 |
|
| 1998 |
Zhang J, Lesort M, Guttmann RP, Johnson GV. Modulation of the in situ activity of tissue transglutaminase by calcium and GTP. The Journal of Biological Chemistry. 273: 2288-95. PMID 9442073 DOI: 10.1074/Jbc.273.4.2288 |
0.346 |
|
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