| Year |
Citation |
Score |
| 2024 |
Kim YK, Won KC, Sussel L. Glucose metabolism partially regulates β-cell function through epigenomic changes. Journal of Diabetes Investigation. PMID 38436511 DOI: 10.1111/jdi.14173 |
0.352 |
|
| 2024 |
Sarkar S, Deiter C, Kyle JE, Guney MA, Sarbaugh D, Yin R, Li X, Cui Y, Ramos-Rodriguez M, Nicora CD, Syed F, Juan-Mateu J, Muralidharan C, Pasquali L, Evans-Molina C, ... ... Sussel L, et al. Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis. Cell Communication and Signaling : Ccs. 22: 141. PMID 38383396 DOI: 10.1186/s12964-023-01437-1 |
0.311 |
|
| 2024 |
You Y, Sarkar S, Deiter C, Elliott EC, Nicora CD, Mirmira RG, Sussel L, Nakayasu ES. Reduction of chemokine CXCL9 expression by omega-3 fatty acids via ADP-ribosylhydrolase ARH3 in MIN6 insulin-producing cells. Biorxiv : the Preprint Server For Biology. PMID 38352306 DOI: 10.1101/2024.01.30.578079 |
0.34 |
|
| 2023 |
Kim YK, Kim YR, Wells KL, Sarbaugh D, Guney M, Tsai CF, Zee T, Karsenty G, Nakayasu ES, Sussel L. PTPN2 regulates metabolic flux to affect beta cell susceptibility to inflammatory stress. Diabetes. PMID 38015772 DOI: 10.2337/db23-0355 |
0.386 |
|
| 2023 |
Abarinov V, Levine JA, Churchill AJ, Hopwood B, Deiter CS, Guney MA, Wells KL, Schrunk JM, Guo Y, Hammelman J, Gifford DK, Magnuson MA, Wichterle H, Sussel L. Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain. Genes & Development. PMID 37364986 DOI: 10.1101/gad.350569.123 |
0.456 |
|
| 2023 |
Brooks EP, Sussel L. Not the second fiddle: α cell development, identity and function in health and diabetes. The Journal of Endocrinology. PMID 37171828 DOI: 10.1530/JOE-22-0297 |
0.341 |
|
| 2022 |
Lorberbaum DS, Sarbaugh D, Sussel L. Leveraging the strengths of mice, human stem cells, and organoids to model pancreas development and diabetes. Frontiers in Endocrinology. 13: 1042611. PMID 36339450 DOI: 10.3389/fendo.2022.1042611 |
0.32 |
|
| 2021 |
Kim YK, Sussel L, Davidson HW. Inherent Beta Cell Dysfunction Contributes to Autoimmune Susceptibility. Biomolecules. 11. PMID 33808310 DOI: 10.3390/biom11040512 |
0.31 |
|
| 2021 |
Docherty FM, Sussel L. Islet Regeneration: Endogenous and Exogenous Approaches. International Journal of Molecular Sciences. 22. PMID 33804882 DOI: 10.3390/ijms22073306 |
0.338 |
|
| 2021 |
Li F, Hu D, Dieter C, Ansong C, Sussel L, Orr G. Single Molecule-based FliFISH Validates Radial and Heterogeneous Gene Expression Patterns in Pancreatic Islet β Cells. Diabetes. PMID 33685924 DOI: 10.2337/db20-0802 |
0.41 |
|
| 2021 |
Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L. Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing pancreas. Development (Cambridge, England). PMID 33658226 DOI: 10.1242/dev.192401 |
0.645 |
|
| 2020 |
Moss ND, Sussel L. mRNA Processing: An Emerging Frontier in the Regulation of Pancreatic β Cell Function. Frontiers in Genetics. 11: 983. PMID 33088281 DOI: 10.3389/fgene.2020.00983 |
0.392 |
|
| 2020 |
Guney MA, Lorberbaum DS, Sussel L. Pancreatic β cell regeneration: To β or not to β. Current Opinion in Physiology. 14: 13-20. PMID 32864533 DOI: 10.1016/J.Cophys.2019.10.019 |
0.465 |
|
| 2020 |
Pajvani UB, Sussel L. An Ultradian Notch in Beta-Cell Development. The New England Journal of Medicine. 383: 80-82. PMID 32609988 DOI: 10.1056/Nejmcibr2001628 |
0.442 |
|
| 2020 |
Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L. Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification. Development (Cambridge, England). PMID 32467243 DOI: 10.1242/Dev.189977 |
0.422 |
|
| 2020 |
Hudish LI, Bubak A, Triolo TM, Niemeyer CS, Sussel L, Nagel M, Taliaferro JM, Russ HA. Modeling Hypoxia-Induced Neuropathies Using a Fast and Scalable Human Motor Neuron Differentiation System. Stem Cell Reports. PMID 32386561 DOI: 10.1016/J.Stemcr.2020.04.003 |
0.307 |
|
| 2020 |
Lorberbaum DS, Docherty FM, Sussel L. Animal Models of Pancreas Development, Developmental Disorders, and Disease. Advances in Experimental Medicine and Biology. 1236: 65-85. PMID 32304069 DOI: 10.1007/978-981-15-2389-2_3 |
0.419 |
|
| 2020 |
Lorberbaum DS, Sussel L. A Notch in Time: Spatiotemporal Analysis of Notch Signaling during Pancreas Development. Developmental Cell. 52: 681-682. PMID 32208161 DOI: 10.1016/J.Devcel.2020.02.018 |
0.435 |
|
| 2020 |
Moss ND, Sussel L. mRNA Processing: An Emerging Frontier in the Regulation of Pancreatic β Cell Function Frontiers in Genetics. 11. DOI: 10.3389/Fgene.2020.00983 |
0.494 |
|
| 2020 |
Lorberbaum D, Sussel L. 2046-P: Retinoic Acid Signaling in Pancreatic Endocrine Cells Regulates Islet Cell Specification Diabetes. 69. DOI: 10.2337/Db20-2046-P |
0.467 |
|
| 2019 |
Singer RA, Arnes L, Cui Y, Wang J, Gao Y, Guney MA, Burnum-Johnson KE, Rabadan R, Ansong C, Orr G, Sussel L. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metabolism. PMID 31607563 DOI: 10.1016/J.Cmet.2019.09.013 |
0.694 |
|
| 2019 |
Romer AI, Singer RA, Sui L, Egli D, Sussel L. Murine Perinatal Beta Cell Proliferation and the Differentiation of Human Stem Cell Derived Insulin Expressing Cells Require NEUROD1. Diabetes. PMID 31519700 DOI: 10.2337/Db19-0117 |
0.693 |
|
| 2019 |
Hudish LI, Reusch JE, Sussel L. β Cell dysfunction during progression of metabolic syndrome to type 2 diabetes. The Journal of Clinical Investigation. PMID 31424428 DOI: 10.1172/Jci129188 |
0.444 |
|
| 2019 |
Hudish LI, Lorberbaum DS, Sussel L. FISHing for β Cells. Developmental Cell. 48: 7-8. PMID 30620904 DOI: 10.1016/J.Devcel.2018.12.007 |
0.456 |
|
| 2018 |
Font-Cunill B, Arnes L, Ferrer J, Sussel L, Beucher A. Long Non-coding RNAs as Local Regulators of Pancreatic Islet Transcription Factor Genes. Frontiers in Genetics. 9: 524. PMID 30459811 DOI: 10.3389/Fgene.2018.00524 |
0.478 |
|
| 2018 |
Bartolome A, Zhu C, Sussel L, Pajvani UB. Notch signaling dynamically regulates adult β cell proliferation and maturity. The Journal of Clinical Investigation. PMID 30375986 DOI: 10.1172/Jci98098 |
0.475 |
|
| 2018 |
Singer RA, Sussel L. Islet Long Noncoding RNAs: A Playbook for Discovery and Characterization. Diabetes. PMID 29937433 DOI: 10.2337/Dbi18-0001 |
0.565 |
|
| 2018 |
Yin R, Kyle JE, Burnum-Johnson KE, Bloodsworth K, Sussel L, Ansong C, Laskin J. High Spatial Resolution Imaging of Mouse Pancreatic Islets Using Nanospray Desorption Electrospray Ionization Mass Spectrometry. Analytical Chemistry. PMID 29718662 DOI: 10.1021/Acs.Analchem.8B00161 |
0.313 |
|
| 2017 |
Cui Y, Hu D, Markillie LM, Chrisler WB, Gaffrey MJ, Ansong C, Sussel L, Orr G. Fluctuation localization imaging-based fluorescence in situ hybridization (fliFISH) for accurate detection and counting of RNA copies in single cells. Nucleic Acids Research. PMID 29040675 DOI: 10.1093/Nar/Gkx874 |
0.398 |
|
| 2017 |
Lorberbaum DS, Sussel L. Gotta Have GATA for Human Pancreas Development. Cell Stem Cell. 20: 577-579. PMID 28475878 DOI: 10.1016/J.Stem.2017.04.004 |
0.43 |
|
| 2017 |
Gutierrez GD, Gromada J, Sussel L. Heterogeneity of the Pancreatic Beta Cell. Frontiers in Genetics. 8: 22. PMID 28321233 DOI: 10.3389/Fgene.2017.00022 |
0.447 |
|
| 2017 |
Churchill AJ, Gutiérrez GD, Singer RA, Lorberbaum DS, Fischer KA, Sussel L. Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development. Elife. 6. PMID 28071588 DOI: 10.7554/Elife.20010 |
0.715 |
|
| 2016 |
Gutiérrez GD, Bender AS, Cirulli V, Mastracci TL, Kelly SM, Tsirigos A, Kaestner KH, Sussel L. Pancreatic β cell identity requires continual repression of non-β cell programs. The Journal of Clinical Investigation. PMID 27941248 DOI: 10.1172/Jci88017 |
0.518 |
|
| 2016 |
Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, ... ... Sussel L, et al. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells. The Journal of Clinical Investigation. PMID 27941246 DOI: 10.1172/Jci88016 |
0.539 |
|
| 2016 |
Gross S, Garofalo DC, Balderes DA, Mastracci TL, Dias JM, Perlmann T, Ericson J, Sussel L. Lmx1a functions in intestinal serotonin-producing enterochromaffin cells downstream of Nkx2.2. Development (Cambridge, England). PMID 27287799 DOI: 10.1242/Dev.130682 |
0.53 |
|
| 2016 |
Arnes L, Akerman I, Balderes DA, Ferrer J, Sussel L. βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function. Genes & Development. 30: 502-7. PMID 26944677 DOI: 10.1101/Gad.273821.115 |
0.498 |
|
| 2016 |
Xuan S, Sussel L. GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development (Cambridge, England). 143: 780-6. PMID 26932670 DOI: 10.1242/Dev.127217 |
0.448 |
|
| 2016 |
Borok MJ, Papaioannou VE, Sussel L. Unique functions of Gata4 in mouse liver induction and heart development. Developmental Biology. 410: 213-22. PMID 26687508 DOI: 10.1016/J.Ydbio.2015.12.007 |
0.381 |
|
| 2016 |
Churchill AJ, Gutiérrez GD, Singer RA, Lorberbaum DS, Fischer KA, Sussel L. Author response: Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development Elife. DOI: 10.7554/Elife.20010.026 |
0.561 |
|
| 2015 |
Gross S, Balderes D, Liu J, Asfaha S, Gu G, Wang TC, Sussel L. Nkx2.2 is expressed in a subset of enteroendocrine cells with expanded lineage potential. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00244.2015. PMID 26492922 DOI: 10.1152/Ajpgi.00244.2015 |
0.507 |
|
| 2015 |
Romer AI, Sussel L. Pancreatic islet cell development and regeneration. Current Opinion in Endocrinology, Diabetes, and Obesity. 22: 255-64. PMID 26087337 DOI: 10.1097/Med.0000000000000174 |
0.51 |
|
| 2015 |
Arnes L, Sussel L. Epigenetic modifications and long noncoding RNAs influence pancreas development and function. Trends in Genetics : Tig. 31: 290-9. PMID 25812926 DOI: 10.1016/J.Tig.2015.02.008 |
0.51 |
|
| 2015 |
Singer RA, Arnes L, Sussel L. Noncoding RNAs in β cell biology. Current Opinion in Endocrinology, Diabetes, and Obesity. 22: 77-85. PMID 25692923 DOI: 10.1097/Med.0000000000000141 |
0.657 |
|
| 2014 |
Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care. 37: 1751-8. PMID 24812433 DOI: 10.2337/Dc14-0396 |
0.389 |
|
| 2014 |
Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. The Journal of Clinical Endocrinology and Metabolism. 99: 1983-92. PMID 24712577 DOI: 10.1210/Jc.2014-1425 |
0.429 |
|
| 2014 |
Zhu Q, Zhao X, Zheng K, Li H, Huang H, Zhang Z, Mastracci T, Wegner M, Chen Y, Sussel L, Qiu M. Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development (Cambridge, England). 141: 548-55. PMID 24449836 DOI: 10.1242/Dev.095323 |
0.366 |
|
| 2013 |
Balderes DA, Magnuson MA, Sussel L. Nkx2.2:Cre knock-in mouse line: a novel tool for pancreas- and CNS-specific gene deletion. Genesis (New York, N.Y. : 2000). 51: 844-51. PMID 23996959 DOI: 10.1002/Dvg.22715 |
0.497 |
|
| 2013 |
Suissa Y, Magenheim J, Stolovich-Rain M, Hija A, Collombat P, Mansouri A, Sussel L, Sosa-Pineda B, McCracken K, Wells JM, Heller RS, Dor Y, Glaser B. Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. Plos One. 8: e70397. PMID 23940571 DOI: 10.1371/Journal.Pone.0070397 |
0.569 |
|
| 2013 |
Mastracci TL, Lin CS, Sussel L. Generation of mice encoding a conditional allele of Nkx2.2. Transgenic Research. 22: 965-72. PMID 23494546 DOI: 10.1007/S11248-013-9700-0 |
0.466 |
|
| 2013 |
Lugani F, Arora R, Papeta N, Patel A, Zheng Z, Sterken R, Singer RA, Caridi G, Mendelsohn C, Sussel L, Papaioannou VE, Gharavi AG. A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse. Plos Genetics. 9: e1003206. PMID 23437001 DOI: 10.1371/Journal.Pgen.1003206 |
0.57 |
|
| 2013 |
Mastracci TL, Anderson KR, Papizan JB, Sussel L. Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas. Plos Genetics. 9: e1003278. PMID 23408910 DOI: 10.1371/Journal.Pgen.1003278 |
0.543 |
|
| 2013 |
Ioannou M, Serafimidis I, Arnes L, Sussel L, Singh S, Vasiliou V, Gavalas A. ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Developmental Biology. 374: 153-63. PMID 23142317 DOI: 10.1016/J.Ydbio.2012.10.030 |
0.486 |
|
| 2012 |
Mastracci TL, Sussel L. The endocrine pancreas: insights into development, differentiation, and diabetes. Wiley Interdisciplinary Reviews. Developmental Biology. 1: 609-28. PMID 23799564 DOI: 10.1002/Wdev.44 |
0.524 |
|
| 2012 |
Arnes L, Hill JT, Gross S, Magnuson MA, Sussel L. Ghrelin expression in the mouse pancreas defines a unique multipotent progenitor population. Plos One. 7: e52026. PMID 23251675 DOI: 10.1371/Journal.Pone.0052026 |
0.557 |
|
| 2012 |
Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, GarcÃa-Hurtado J, RodrÃguez-Seguà S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, ... ... Sussel L, et al. Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metabolism. 16: 435-48. PMID 23040067 DOI: 10.1016/J.Cmet.2012.08.010 |
0.504 |
|
| 2012 |
Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. The Journal of Clinical Investigation. 122: 3516-28. PMID 23006325 DOI: 10.1172/Jci63352 |
0.446 |
|
| 2012 |
Talchai C, Xuan S, Lin HV, Sussel L, Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell. 150: 1223-34. PMID 22980982 DOI: 10.1016/J.Cell.2012.07.029 |
0.628 |
|
| 2012 |
Sussel L. Advances in pancreas development: generation informs regeneration. Seminars in Cell & Developmental Biology. 23: 655. PMID 22749955 DOI: 10.1016/J.Semcdb.2012.06.007 |
0.516 |
|
| 2012 |
Arnes L, Leclerc K, Friel JM, Hipkens SB, Magnuson MA, Sussel L. Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology. Genesis (New York, N.Y. : 2000). 50: 612-24. PMID 22539496 DOI: 10.1002/Dvg.22037 |
0.508 |
|
| 2011 |
Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L. Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming. Genes & Development. 25: 2291-305. PMID 22056672 DOI: 10.1101/Gad.173039.111 |
0.657 |
|
| 2011 |
Mastracci TL, Wilcox CL, Arnes L, Panea C, Golden JA, May CL, Sussel L. Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Developmental Biology. 359: 1-11. PMID 21856296 DOI: 10.1016/J.Ydbio.2011.08.001 |
0.559 |
|
| 2011 |
Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L. The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development (Cambridge, England). 138: 3213-24. PMID 21750032 DOI: 10.1242/Dev.058693 |
0.695 |
|
| 2011 |
Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ. Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development (Cambridge, England). 138: 531-41. PMID 21205797 DOI: 10.1242/Dev.058917 |
0.341 |
|
| 2011 |
Xuan S, Borok M, Duncan S, Sussel L. Transcription factors Gata4 and Gata6 play compensatory roles in pancreas development Developmental Biology. 356: 240. DOI: 10.1016/J.Ydbio.2011.05.422 |
0.331 |
|
| 2010 |
Lek M, Dias JM, Marklund U, Uhde CW, Kurdija S, Lei Q, Sussel L, Rubenstein JL, Matise MP, Arnold HH, Jessell TM, Ericson J. A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development (Cambridge, England). 137: 4051-60. PMID 21062862 DOI: 10.1242/Dev.054288 |
0.564 |
|
| 2010 |
Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R. Islet β-cell-specific MafA transcription requires the 5′-Flanking conserved region 3 control domain Molecular and Cellular Biology. 30: 4234-4244. PMID 20584984 DOI: 10.1128/Mcb.01396-09 |
0.389 |
|
| 2010 |
Gu C, Stein GH, Pan N, Goebbels S, Hörnberg H, Nave KA, Herrera P, White P, Kaestner KH, Sussel L, Lee JE. Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metabolism. 11: 298-310. PMID 20374962 DOI: 10.1016/J.Cmet.2010.03.006 |
0.461 |
|
| 2010 |
Hill JT, Chao CS, Anderson KR, Kaufman F, Johnson CW, Sussel L. Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Molecular Endocrinology (Baltimore, Md.). 24: 381-90. PMID 19965928 DOI: 10.1210/Me.2009-0360 |
0.524 |
|
| 2010 |
Roybon L, Mastracci TL, Ribeiro D, Sussel L, Brundin P, Li JY. GABAergic differentiation induced by Mash1 is compromised by the bHLH proteins Neurogenin2, NeuroD1, and NeuroD2. Cerebral Cortex (New York, N.Y. : 1991). 20: 1234-44. PMID 19767311 DOI: 10.1093/Cercor/Bhp187 |
0.379 |
|
| 2009 |
Anderson KR, White P, Kaestner KH, Sussel L. Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development. Bmc Developmental Biology. 9: 65. PMID 20003319 DOI: 10.1186/1471-213X-9-65 |
0.568 |
|
| 2009 |
Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L. Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. The Journal of Biological Chemistry. 284: 31236-48. PMID 19759004 DOI: 10.1074/Jbc.M109.048694 |
0.501 |
|
| 2009 |
Prakash N, Puelles E, Freude K, Trümbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, Wurst W. Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. Development (Cambridge, England). 136: 2545-55. PMID 19592574 DOI: 10.1242/Dev.031781 |
0.311 |
|
| 2009 |
Hill JT, Mastracci TL, Vinton C, Doyle ML, Anderson KR, Loomis ZL, Schrunk JM, Minic AD, Prabakar KR, Pugliese A, Sun Y, Smith RG, Sussel L. Ghrelin is dispensable for embryonic pancreatic islet development and differentiation. Regulatory Peptides. 157: 51-6. PMID 19268691 DOI: 10.1016/J.Regpep.2009.02.013 |
0.505 |
|
| 2009 |
Jedlicka P, Sui X, Sussel L, Gutierrez-Hartmann A. Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine. The American Journal of Pathology. 174: 1280-90. PMID 19264912 DOI: 10.2353/Ajpath.2009.080409 |
0.412 |
|
| 2008 |
Desai S, Loomis Z, Pugh-Bernard A, Schrunk J, Doyle MJ, Minic A, McCoy E, Sussel L. Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Developmental Biology. 313: 58-66. PMID 18022152 DOI: 10.1016/J.Ydbio.2007.09.047 |
0.755 |
|
| 2008 |
Anderson KR, Sussel L. Nkx2.2 transcriptional targets important for islet differentiation Developmental Biology. 319: 573. DOI: 10.1016/J.Ydbio.2008.05.376 |
0.349 |
|
| 2007 |
Chao CS, Loomis ZL, Lee JE, Sussel L. Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Developmental Biology. 312: 523-32. PMID 17988662 DOI: 10.1016/J.Ydbio.2007.09.057 |
0.489 |
|
| 2007 |
Doyle MJ, Sussel L. Nkx2.2 regulates beta-cell function in the mature islet. Diabetes. 56: 1999-2007. PMID 17456846 DOI: 10.2337/Db06-1766 |
0.743 |
|
| 2007 |
Doyle MJ, Loomis ZL, Sussel L. Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development (Cambridge, England). 134: 515-23. PMID 17202186 DOI: 10.1242/Dev.02763 |
0.768 |
|
| 2006 |
Decker K, Goldman DC, Grasch CL, Sussel L. Gata6 is an important regulator of mouse pancreas development. Developmental Biology. 298: 415-29. PMID 16887115 DOI: 10.1016/J.Ydbio.2006.06.046 |
0.509 |
|
| 2006 |
Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R. FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. Molecular and Cellular Biology. 26: 5735-43. PMID 16847327 DOI: 10.1128/Mcb.00249-06 |
0.472 |
|
| 2006 |
Prakash N, Brodski C, Naserke T, Puelles E, Gogoi R, Hall A, Panhuysen M, Echevarria D, Sussel L, Weisenhorn DM, Martinez S, Arenas E, Simeone A, Wurst W. A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (Cambridge, England). 133: 89-98. PMID 16339193 DOI: 10.1242/Dev.02181 |
0.359 |
|
| 2004 |
Doyle MJ, Sussel L. Engineering islets: lessons from stem cells and embryonic development. Endocrinology and Metabolism Clinics of North America. 33: 149-62, x. PMID 15053900 DOI: 10.1016/S0889-8529(03)00100-2 |
0.743 |
|
| 2004 |
Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L. Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proceedings of the National Academy of Sciences of the United States of America. 101: 2924-9. PMID 14970313 DOI: 10.1073/Pnas.0308604100 |
0.557 |
|
| 2004 |
Wang J, Elghazi L, Parker SE, Kizilocak H, Asano M, Sussel L, Sosa-Pineda B. The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic β-cell differentiation Developmental Biology. 266: 178-189. PMID 14729487 DOI: 10.1016/J.Ydbio.2003.10.018 |
0.565 |
|
| 2004 |
Chao CS, Sussel L. Ghrelin, insulin, and the pancreatic islet Current Opinion in Endocrinology & Diabetes. 11: 104-109. DOI: 10.1097/01.Med.0000129637.11768.93 |
0.333 |
|
| 2003 |
Cissell MA, Zhao L, Sussel L, Henderson E, Stein R. Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2. The Journal of Biological Chemistry. 278: 751-6. PMID 12426319 DOI: 10.1074/Jbc.M205905200 |
0.414 |
|
| 1999 |
Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM, Rubenstein JL, Ericson J. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature. 398: 622-7. PMID 10217145 DOI: 10.1038/19315 |
0.552 |
|
| 1998 |
Qiu M, Shimamura K, Sussel L, Chen S, Rubenstein JL. Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development. Mechanisms of Development. 72: 77-88. PMID 9533954 DOI: 10.1016/S0925-4773(98)00018-5 |
0.522 |
|
| 1993 |
Sussel L, Vannier D, Shore D. Epigenetic switching of transcriptional states: cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae. Molecular and Cellular Biology. 13: 3919-28. PMID 8321199 DOI: 10.1128/Mcb.13.7.3919 |
0.386 |
|
| 1992 |
Hardy CF, Sussel L, Shore D. A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation. Genes & Development. 6: 801-14. PMID 1577274 DOI: 10.1101/Gad.6.5.801 |
0.31 |
|
| 1991 |
Sussel L, Shore D. Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length. Proceedings of the National Academy of Sciences of the United States of America. 88: 7749-53. PMID 1881914 DOI: 10.1073/Pnas.88.17.7749 |
0.336 |
|
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