| Year |
Citation |
Score |
| 2023 |
Kao HY, Pai CP, Wang H, Agarwal N, Adams J, Liu Z, Seachrist D, Keri R, Schiemann W. The PML1-WDR5 axis regulates H3K4me3 marks and promotes stemness of estrogen receptor-positive breast cancer. Research Square. PMID 37720048 DOI: 10.21203/rs.3.rs-3266720/v1 |
0.343 |
|
| 2022 |
Robinson NJ, Schiemann WP. Telomerase in Cancer: Function, Regulation, and Clinical Translation. Cancers. 14. PMID 35159075 DOI: 10.3390/cancers14030808 |
0.301 |
|
| 2022 |
Wang W, Rana PS, Alkrekshi A, Bialkowska K, Markovic V, Schiemann WP, Plow EF, Pluskota E, Sossey-Alaoui K. Targeted Deletion of Kindlin-2 in Mouse Mammary Glands Inhibits Tumor Growth, Invasion, and Metastasis Downstream of a TGF-β/EGF Oncogenic Signaling Pathway. Cancers. 14. PMID 35158908 DOI: 10.3390/cancers14030639 |
0.408 |
|
| 2021 |
Parker KA, Gooding AJ, Valadkhan S, Schiemann WP. lncRNA BORG:TRIM28 Complexes Drive Metastatic Progression by Inducing a6 Integrin/CD49f Expression in Breast Cancer Stem Cells. Molecular Cancer Research : McR. PMID 34497119 DOI: 10.1158/1541-7786.MCR-21-0137 |
0.326 |
|
| 2020 |
Hill HE, Schiemann WP, Varadan V. Understanding breast cancer disparities-a multi-scale challenge. Annals of Translational Medicine. 8: 906. PMID 32793750 DOI: 10.21037/Atm.2020.04.37 |
0.344 |
|
| 2020 |
Robinson NJ, Parker KA, Schiemann WP. Epigenetic plasticity in metastatic dormancy: mechanisms and therapeutic implications. Annals of Translational Medicine. 8: 903. PMID 32793747 DOI: 10.21037/Atm.2020.02.177 |
0.367 |
|
| 2020 |
Gooding AJ, Schiemann WP. Epithelial-Mesenchymal Transition Programs and Cancer Stem Cell Phenotypes: Mediators of Breast Cancer Therapy Resistance. Molecular Cancer Research : McR. PMID 32503922 DOI: 10.1158/1541-7786.Mcr-20-0067 |
0.427 |
|
| 2020 |
Schiemann WP. Introduction to this special issue “Breast Cancer Metastasis” Journal of Cancer Metastasis and Treatment. 2020. DOI: 10.20517/2394-4722.2020.01 |
0.319 |
|
| 2020 |
Robinson NJ, Taylor DJ, Schiemann WP. Abstract 112: Telomere proteins coordinate intracellular signaling to control telomere maintenance mechanism selection and metastatic recurrence Immunology. 80: 112-112. DOI: 10.1158/1538-7445.Am2020-112 |
0.433 |
|
| 2019 |
Robinson NJ, Taylor DJ, Schiemann WP. Stem cells, immortality, and the evolution of metastatic properties in breast cancer: telomere maintenance mechanisms and metastatic evolution. Journal of Cancer Metastasis and Treatment. 5. PMID 31440584 DOI: 10.20517/2394-4722.2019.15 |
0.407 |
|
| 2019 |
Gooding AJ, Parker KA, Valadkhan S, Schiemann WP. The IncRNA BORG: A novel inducer of TNBC metastasis, chemoresistance, and disease recurrence. Journal of Cancer Metastasis and Treatment. 5. PMID 31435529 DOI: 10.20517/2394-4722.2019.11 |
0.451 |
|
| 2019 |
Flynn AB, Schiemann WP. Autophagy in breast cancer metastatic dormancy: Tumor suppressing or tumor promoting functions? Journal of Cancer Metastasis and Treatment. 5. PMID 31431926 DOI: 10.20517/2394-4722.2019.13 |
0.429 |
|
| 2019 |
La Belle Flynn A, Calhoun BC, Sharma A, Chang JC, Almasan A, Schiemann WP. Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression. Nature Communications. 10: 3668. PMID 31413316 DOI: 10.1038/S41467-019-11640-9 |
0.398 |
|
| 2019 |
Covarrubias G, He F, Raghunathan S, Turan O, Peiris PM, Schiemann WP, Karathanasis E. Effective treatment of cancer metastasis using a dual-ligand nanoparticle. Plos One. 14: e0220474. PMID 31356633 DOI: 10.1371/Journal.Pone.0220474 |
0.348 |
|
| 2019 |
Hernandez-Sanchez W, Huang W, Plucinsky B, Garcia-Vazquez N, Robinson NJ, Schiemann WP, Berdis AJ, Skordalakes E, Taylor DJ. A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity. Plos Biology. 17: e3000204. PMID 30951520 DOI: 10.1371/Journal.Pbio.3000204 |
0.333 |
|
| 2019 |
Vaidya A, Sun Z, Ayat N, Schilb A, Liu X, Jiang H, Sun D, Scheidt J, Qian V, He S, Gilmore H, Schiemann WP, Lu ZR. Systemic Delivery of Tumor-Targeting siRNA Nanoparticles against an Oncogenic LncRNA Facilitates Effective Triple-Negative Breast Cancer Therapy. Bioconjugate Chemistry. PMID 30739442 DOI: 10.1021/Acs.Bioconjchem.9B00028 |
0.32 |
|
| 2018 |
Gooding AJ, Zhang B, Gunawardane L, Beard A, Valadkhan S, Schiemann WP. The lncRNA BORG facilitates the survival and chemoresistance of triple-negative breast cancers. Oncogene. PMID 30467380 DOI: 10.1038/S41388-018-0586-4 |
0.318 |
|
| 2018 |
Chakraborty S, Jiang C, Gau D, Oddo M, Ding Z, Vollmer L, Joy M, Schiemann W, Stolz DB, Vogt A, Ghosh S, Roy P. Profilin-1 deficiency leads to SMAD3 upregulation and impaired 3D outgrowth of breast cancer cells. British Journal of Cancer. PMID 30318519 DOI: 10.1038/S41416-018-0284-6 |
0.445 |
|
| 2018 |
Sossey-Alaoui K, Pluskota E, Szpak D, Schiemann WP, Plow EF. The Kindlin-2 regulation of epithelial-to-mesenchymal transition in breast cancer metastasis is mediated through miR-200b. Scientific Reports. 8: 7360. PMID 29743493 DOI: 10.1038/s41598-018-25373-0 |
0.327 |
|
| 2017 |
Bledzka K, Schiemann B, Schiemann WP, Fox P, Plow EF, Sossey-Alaoui K. The WAVE3-YB1 interaction regulates cancer stem cells activity in breast cancer. Oncotarget. 8: 104072-104089. PMID 29262622 DOI: 10.18632/Oncotarget.22009 |
0.355 |
|
| 2017 |
La Belle A, Khatib J, Schiemann WP, Vinayak S. Role of Platinum in Early-Stage Triple-Negative Breast Cancer. Current Treatment Options in Oncology. 18: 68. PMID 29110096 DOI: 10.1007/S11864-017-0506-9 |
0.316 |
|
| 2017 |
Gooding AJ, Zhang B, Jahanbani FK, Gilmore HL, Chang JC, Valadkhan S, Schiemann WP. The lncRNA BORG Drives Breast Cancer Metastasis and Disease Recurrence. Scientific Reports. 7: 12698. PMID 28983112 DOI: 10.1038/S41598-017-12716-6 |
0.302 |
|
| 2017 |
Tian M, Schiemann WP. TGF-β Stimulation of EMT Programs Elicits Non-genomic ER-α Activity and Anti-estrogen Resistance in Breast Cancer Cells. Journal of Cancer Metastasis and Treatment. 3: 150-160. PMID 28955730 DOI: 10.20517/2394-4722.2017.38 |
0.468 |
|
| 2017 |
Han Z, Wu X, Roelle S, Chen C, Schiemann WP, Lu ZR. Targeted gadofullerene for sensitive magnetic resonance imaging and risk-stratification of breast cancer. Nature Communications. 8: 692. PMID 28947734 DOI: 10.1038/S41467-017-00741-Y |
0.331 |
|
| 2017 |
Sossey-Alaoui K, Pluskota E, Bialkowska K, Szpak D, Parker Y, Morrison C, Lindner DJ, Schiemann WP, Plow EF. Kindlin-2 regulates the growth of breast cancer tumors by activating CSF-1-mediated macrophage infiltration. Cancer Research. PMID 28687620 DOI: 10.1158/0008-5472.CAN-16-2337 |
0.432 |
|
| 2017 |
La Belle AA, Schiemann WP. The propensity for epithelial-mesenchymal transitions is dictated by chromatin states in the cancer cell of origin. Stem Cell Investigation. 4: 44. PMID 28607918 DOI: 10.21037/Sci.2017.04.07 |
0.375 |
|
| 2017 |
Parvani JG, Gujrati MD, Mack MA, Schiemann WP, Lu Z. Abstract B45: Silencing ß3 integrin by targeted ECO/siRNA nanoparticles inhibits EMT and metastasis of triple-negative breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-B45 |
0.445 |
|
| 2016 |
Gooding AJ, Schiemann WP. Harnessing protein kinase A activation to induce mesenchymal-epithelial programs to eliminate chemoresistant, tumor-initiating breast cancer cells. Translational Cancer Research. 5: S226-S232. PMID 28680830 DOI: 10.21037/Tcr.2016.08.09 |
0.442 |
|
| 2016 |
Robinson NJ, Schiemann WP. Means to the ends: The role of telomeres and telomere processing machinery in metastasis. Biochimica Et Biophysica Acta. PMID 27768860 DOI: 10.1016/J.Bbcan.2016.10.005 |
0.393 |
|
| 2016 |
Morrison CD, Allington TM, Thompson CL, Gilmore HL, Chang JC, Keri RA, Schiemann WP. c-Abl inhibits breast cancer tumorigenesis through reactivation of p53-mediated p21 expression. Oncotarget. PMID 27626309 DOI: 10.18632/Oncotarget.11909 |
0.788 |
|
| 2016 |
Gupta S, Hau AM, Al-Ahmadie HA, Harwalkar J, Shoskes AC, Elson P, Beach JR, Hussey GS, Schiemann WP, Egelhoff TT, Howe PH, Hansel DE. Transforming Growth Factor-β Is an Upstream Regulator of Mammalian Target of Rapamycin Complex 2-Dependent Bladder Cancer Cell Migration and Invasion. The American Journal of Pathology. PMID 26988652 DOI: 10.1016/J.Ajpath.2016.01.008 |
0.569 |
|
| 2016 |
Gollamudi J, Parvani JG, Schiemann WP, Vinayak S. Neoadjuvant therapy for early-stage breast cancer: the clinical utility of pertuzumab. Cancer Management and Research. 8: 21-31. PMID 26937204 DOI: 10.2147/Cmar.S55279 |
0.399 |
|
| 2016 |
Davuluri G, Schiemann WP, Plow EF, Sossey-Alaoui K. Abstract A49: WAVE3 modulates sensitivity of TNBCs to chemotherapeutics by inhibiting the STAT-HIF-1α-mediated angiogenesis Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-A49 |
0.381 |
|
| 2015 |
Thomas DG, Yenepalli A, Denais CM, Rape A, Beach JR, Wang YL, Schiemann WP, Baskaran H, Lammerding J, Egelhoff TT. Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion. The Journal of Cell Biology. PMID 26261182 DOI: 10.1083/Jcb.201502039 |
0.306 |
|
| 2015 |
Correa D, Somoza RA, Lin P, Schiemann WP, Caplan AI. Mesenchymal Stem Cells regulate Melanoma Cancer Cells extravasation to bone and liver at their perivascular niche. International Journal of Cancer. Journal International Du Cancer. PMID 26235173 DOI: 10.1002/Ijc.29709 |
0.368 |
|
| 2015 |
Doolittle E, Peiris PM, Doron G, Goldberg A, Tucci S, Rao S, Shah S, Sylvestre M, Govender P, Turan O, Lee Z, Schiemann WP, Karathanasis E. Spatiotemporal Targeting of a Dual-Ligand Nanoparticle to Cancer Metastasis. Acs Nano. 9: 8012-21. PMID 26203676 DOI: 10.1021/Acsnano.5B01552 |
0.316 |
|
| 2015 |
Morrison CD, Schiemann WP. Tipping the balance between good and evil: aberrant 14-3-3ζ expression drives oncogenic TGF-β signaling in metastatic breast cancers. Breast Cancer Research : Bcr. 17: 92. PMID 26160166 DOI: 10.1186/S13058-015-0603-2 |
0.602 |
|
| 2015 |
Peiris PM, Deb P, Doolittle E, Doron G, Goldberg A, Govender P, Shah S, Rao S, Carbone S, Cotey T, Sylvestre M, Singh S, Schiemann WP, Lee Z, Karathanasis E. Vascular Targeting of a Gold Nanoparticle to Breast Cancer Metastasis. Journal of Pharmaceutical Sciences. 104: 2600-10. PMID 26036431 DOI: 10.1002/Jps.24518 |
0.311 |
|
| 2015 |
Parvani JG, Gujrati MD, Mack MA, Schiemann WP, Lu ZR. Silencing β3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer. Cancer Research. 75: 2316-25. PMID 25858145 DOI: 10.1158/0008-5472.Can-14-3485 |
0.455 |
|
| 2015 |
Parvani JG, Davuluri G, Wendt MK, Espinosa C, Tian M, Danielpour D, Sossey-Alaoui K, Schiemann WP. Deptor enhances triple-negative breast cancer metastasis and chemoresistance through coupling to survivin expression. Neoplasia (New York, N.Y.). 17: 317-28. PMID 25810016 DOI: 10.1016/J.Neo.2015.02.003 |
0.536 |
|
| 2015 |
Wendt MK, Williams WK, Pascuzzi PE, Balanis NG, Schiemann BJ, Carlin CR, Schiemann WP. The antitumorigenic function of EGFR in metastatic breast cancer is regulated by expression of Mig6. Neoplasia (New York, N.Y.). 17: 124-33. PMID 25622905 DOI: 10.1016/J.Neo.2014.11.009 |
0.429 |
|
| 2015 |
Morrison CD, Gilmore H, Schiemann WP. Abstract P4-05-08: Cellular localization dictates the role for c-Abl in breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P4-05-08 |
0.409 |
|
| 2015 |
Parvani JG, Chu V, Roelle S, Lu Z, Schiemann W. Abstract 399: Nanoparticle silencing of β1 and β3 integrins augments Dasatinib sensitivity Cancer Research. 75: 399-399. DOI: 10.1158/1538-7445.Am2015-399 |
0.619 |
|
| 2015 |
Davuluri G, Plow EF, Schiemann WP, Sossey-Alaoui K. Abstract 2925: WAVE3 is associated with chemoresistance in TNBC by activating tumor angiogenesis downstream of the STAT1/Hif-1α/VEGF-A signaling axis Cancer Research. 75: 2925-2925. DOI: 10.1158/1538-7445.Am2015-2925 |
0.394 |
|
| 2014 |
Lee YH, Schiemann WP. Chemotherapeutic Targeting of the Transforming Growth Factor-β Pathway in Breast Cancers. Breast Cancer Management. 3: 73-85. PMID 25904986 DOI: 10.2217/Bmt.13.74 |
0.571 |
|
| 2014 |
Davuluri G, Augoff K, Schiemann WP, Plow EF, Sossey-Alaoui K. WAVE3-NFκB interplay is essential for the survival and invasion of cancer cells. Plos One. 9: e110627. PMID 25329315 DOI: 10.1371/Journal.Pone.0110627 |
0.38 |
|
| 2014 |
Wendt MK, Taylor MA, Schiemann BJ, Sossey-Alaoui K, Schiemann WP. Fibroblast growth factor receptor splice variants are stable markers of oncogenic transforming growth factor β1 signaling in metastatic breast cancers. Breast Cancer Research : Bcr. 16: R24. PMID 24618085 DOI: 10.1186/Bcr3623 |
0.518 |
|
| 2014 |
Holtzhausen A, Golzio C, How T, Lee YH, Schiemann WP, Katsanis N, Blobe GC. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 1248-67. PMID 24308972 DOI: 10.1096/Fj.13-239178 |
0.514 |
|
| 2013 |
Taylor MA, Davuluri G, Parvani JG, Schiemann BJ, Wendt MK, Plow EF, Schiemann WP, Sossey-Alaoui K. Upregulated WAVE3 expression is essential for TGF-β-mediated EMT and metastasis of triple-negative breast cancer cells. Breast Cancer Research and Treatment. 142: 341-53. PMID 24197660 DOI: 10.1007/S10549-013-2753-1 |
0.52 |
|
| 2013 |
Parvani JG, Galliher-Beckley AJ, Schiemann BJ, Schiemann WP. Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β. Molecular Biology of the Cell. 24: 3449-59. PMID 24006485 DOI: 10.1091/Mbc.E12-10-0776 |
0.509 |
|
| 2013 |
Parvani JG, Schiemann WP. Sox4, EMT programs, and the metastatic progression of breast cancers: mastering the masters of EMT. Breast Cancer Research : Bcr. 15: R72. PMID 23981787 DOI: 10.1186/Bcr3466 |
0.462 |
|
| 2013 |
Balanis N, Wendt MK, Schiemann BJ, Wang Z, Schiemann WP, Carlin CR. Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway. The Journal of Biological Chemistry. 288: 17954-67. PMID 23653350 DOI: 10.1074/Jbc.M113.475277 |
0.456 |
|
| 2013 |
Morrison CD, Parvani JG, Schiemann WP. The relevance of the TGF-β Paradox to EMT-MET programs. Cancer Letters. 341: 30-40. PMID 23474494 DOI: 10.1016/J.Canlet.2013.02.048 |
0.508 |
|
| 2013 |
Taylor MA, Sossey-Alaoui K, Thompson CL, Danielpour D, Schiemann WP. TGF-β upregulates miR-181a expression to promote breast cancer metastasis. The Journal of Clinical Investigation. 123: 150-63. PMID 23241956 DOI: 10.1172/Jci64946 |
0.424 |
|
| 2013 |
Taylor MA, Davuluri G, McCue B, Plow EF, Schiemann WP, Sossey-Alaoui K. Abstract C34: WAVE3 is required for TGF-β-mediated EMT Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-C34 |
0.493 |
|
| 2013 |
Parvani JG, Taylor MA, Schiemann WP. Abstract B46: The role of integrin switching and Deptor in metastatic breast cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B46 |
0.543 |
|
| 2013 |
Lee Y, Schiemann WP. Abstract A8: Fibulin-5 (FBLN5) initiates EMT and induces MMPs expression via β1 integrin/EGFR/ERK pathway Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A8 |
0.557 |
|
| 2013 |
Wendt MK, Balanis N, Schiemann B, Carlin C, Schiemann W. Abstract A17: Regulation of EGFR: Stat3 signaling by Mig6 is required for metastatic outgrowth in triple-negative breast cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A17 |
0.45 |
|
| 2013 |
Morrison CD, Schiemann W. Abstract A103: Investigation of novel therapeutic and diagnostic strategies for the management of triple-negative breast cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A103 |
0.486 |
|
| 2013 |
Wendt MK, Parvani J, Schiemann B, Sossey-Aiaoui K, Schiemann W. Abstract A159: The inherent resistant of breast cancer to EGFR-targeted therapies is driven by EMT-induced expression of particular FGFR splice variants. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A159 |
0.455 |
|
| 2012 |
Wendt MK, Schiemann BJ, Parvani JG, Lee YH, Kang Y, Schiemann WP. TGF-β stimulates Pyk2 expression as part of an epithelial-mesenchymal transition program required for metastatic outgrowth of breast cancer. Oncogene. 32: 2005-15. PMID 22710711 DOI: 10.1038/Onc.2012.230 |
0.54 |
|
| 2012 |
Wendt MK, Tian M, Schiemann WP. Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression. Cell and Tissue Research. 347: 85-101. PMID 21691718 DOI: 10.1007/S00441-011-1199-1 |
0.568 |
|
| 2012 |
Taylor MA, Schiemann WP. Abstract A33: The role of microRNA-181a in TGF- -mediated breast cancer progression Cancer Research. 72: A33-A33. DOI: 10.1158/1538-7445.Nonrna12-A33 |
0.543 |
|
| 2012 |
Wendt MK, Balanis N, Carlin C, Schiemann W. Abstract A24: Fibronectin-mediated activation of Stat3 facilitates the resistance of triple negative breast cancer to EGFR-targeted therapies Clinical Cancer Research. 18: A24-A24. DOI: 10.1158/1078-0432.Mechres-A24 |
0.46 |
|
| 2011 |
Taylor MA, Lee YH, Schiemann WP. Role of TGF-β and the tumor microenvironment during mammary tumorigenesis. Gene Expression. 15: 117-32. PMID 22268294 DOI: 10.3727/105221611X13176664479322 |
0.562 |
|
| 2011 |
Wendt MK, Molter J, Flask CA, Schiemann WP. In vivo dual substrate bioluminescent imaging. Journal of Visualized Experiments : Jove. PMID 22006228 DOI: 10.3791/3245 |
0.445 |
|
| 2011 |
Balanis N, Yoshigi M, Wendt MK, Schiemann WP, Carlin CR. β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells. Molecular Biology of the Cell. 22: 4288-301. PMID 21937717 DOI: 10.1091/Mbc.E10-08-0700 |
0.459 |
|
| 2011 |
Yori JL, Seachrist DD, Johnson E, Lozada KL, Abdul-Karim FW, Chodosh LA, Schiemann WP, Keri RA. Krüppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. Neoplasia (New York, N.Y.). 13: 601-10. PMID 21750654 DOI: 10.1593/Neo.11260 |
0.476 |
|
| 2011 |
Wendt MK, Taylor MA, Schiemann BJ, Schiemann WP. Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer. Molecular Biology of the Cell. 22: 2423-35. PMID 21613543 DOI: 10.1091/Mbc.E11-04-0306 |
0.478 |
|
| 2011 |
Taylor MA, Amin JD, Kirschmann DA, Schiemann WP. Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells. Neoplasia (New York, N.Y.). 13: 406-18. PMID 21532881 DOI: 10.1593/Neo.101086 |
0.597 |
|
| 2011 |
Parvani JG, Taylor MA, Schiemann WP. Noncanonical TGF-β signaling during mammary tumorigenesis. Journal of Mammary Gland Biology and Neoplasia. 16: 127-46. PMID 21448580 DOI: 10.1007/S10911-011-9207-3 |
0.584 |
|
| 2011 |
Lee YH, Schiemann WP. Fibromodulin suppresses nuclear factor-kappaB activity by inducing the delayed degradation of IKBA via a JNK-dependent pathway coupled to fibroblast apoptosis. The Journal of Biological Chemistry. 286: 6414-22. PMID 21156791 DOI: 10.1074/Jbc.M110.168682 |
0.42 |
|
| 2011 |
Allington TM, Schiemann WP. The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cells. Cells, Tissues, Organs. 193: 98-113. PMID 21051857 DOI: 10.1159/000320163 |
0.828 |
|
| 2011 |
Tian M, Neil JR, Schiemann WP. Transforming growth factor-β and the hallmarks of cancer. Cellular Signalling. 23: 951-62. PMID 20940046 DOI: 10.1016/J.Cellsig.2010.10.015 |
0.838 |
|
| 2011 |
Tobi M, Kim M, Zimmer R, Hatfield J, Kam M, Khoury N, Carville A, Lawson MJ, Schiemann WP, Thomas P. Colorectal cancer in the cotton top tamarin (Saguinus oedipus): how do they evade liver metastasis? Digestive Diseases and Sciences. 56: 397-405. PMID 20645001 DOI: 10.1007/S10620-010-1314-2 |
0.314 |
|
| 2010 |
Micalizzi DS, Wang CA, Farabaugh SM, Schiemann WP, Ford HL. Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth. Cancer Research. 70: 10371-80. PMID 21056993 DOI: 10.1158/0008-5472.Can-10-1354 |
0.631 |
|
| 2010 |
Wendt MK, Smith JA, Schiemann WP. Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression. Oncogene. 29: 6485-98. PMID 20802523 DOI: 10.1038/Onc.2010.377 |
0.586 |
|
| 2010 |
Taylor MA, Parvani JG, Schiemann WP. The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells. Journal of Mammary Gland Biology and Neoplasia. 15: 169-90. PMID 20467795 DOI: 10.1007/S10911-010-9181-1 |
0.672 |
|
| 2010 |
Tian M, Schiemann WP. PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 1105-16. PMID 19897661 DOI: 10.1096/Fj.09-141341 |
0.648 |
|
| 2009 |
Wendt MK, Allington TM, Schiemann WP. Mechanisms of the epithelial-mesenchymal transition by TGF-beta. Future Oncology (London, England). 5: 1145-68. PMID 19852727 DOI: 10.2217/Fon.09.90 |
0.844 |
|
| 2009 |
Keshamouni VG, Schiemann WP. Epithelial-mesenchymal transition in tumor metastasis: a method to the madness. Future Oncology (London, England). 5: 1109-11. PMID 19852724 DOI: 10.2217/Fon.09.87 |
0.462 |
|
| 2009 |
Wendt MK, Smith JA, Schiemann WP. p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity. The Journal of Biological Chemistry. 284: 34145-56. PMID 19822523 DOI: 10.1074/Jbc.M109.023614 |
0.678 |
|
| 2009 |
Wendt MK, Schiemann WP. Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis. Breast Cancer Research : Bcr. 11: R68. PMID 19740433 DOI: 10.1186/Bcr2360 |
0.615 |
|
| 2009 |
Micalizzi DS, Christensen KL, Jedlicka P, Coletta RD, Barón AE, Harrell JC, Horwitz KB, Billheimer D, Heichman KA, Welm AL, Schiemann WP, Ford HL. The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling. The Journal of Clinical Investigation. 119: 2678-90. PMID 19726885 DOI: 10.1172/Jci37815 |
0.65 |
|
| 2009 |
Tian M, Schiemann WP. Preclinical efficacy of cystatin C to target the oncogenic activity of transforming growth factor Beta in breast cancer. Translational Oncology. 2: 174-83. PMID 19701502 DOI: 10.1593/Tlo.09145 |
0.688 |
|
| 2009 |
Allington TM, Galliher-Beckley AJ, Schiemann WP. Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 4231-43. PMID 19690215 DOI: 10.1096/Fj.09-138412 |
0.843 |
|
| 2009 |
Neil JR, Tian M, Schiemann WP. X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression. The Journal of Biological Chemistry. 284: 21209-17. PMID 19531477 DOI: 10.1074/Jbc.M109.018374 |
0.862 |
|
| 2009 |
Tian M, Schiemann WP. The TGF-beta paradox in human cancer: an update. Future Oncology (London, England). 5: 259-71. PMID 19284383 DOI: 10.2217/14796694.5.2.259 |
0.643 |
|
| 2008 |
Neil JR, Johnson KM, Nemenoff RA, Schiemann WP. Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms. Carcinogenesis. 29: 2227-35. PMID 18725385 DOI: 10.1093/Carcin/Bgn202 |
0.871 |
|
| 2008 |
Xiao YQ, Freire-de-Lima CG, Schiemann WP, Bratton DL, Vandivier RW, Henson PM. Transcriptional and translational regulation of TGF-beta production in response to apoptotic cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 3575-85. PMID 18714031 DOI: 10.4049/Jimmunol.181.5.3575 |
0.611 |
|
| 2008 |
Lee YH, Albig AR, Regner M, Schiemann BJ, Schiemann WP. Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-beta in mammary epithelial cells via a MMP-dependent mechanism. Carcinogenesis. 29: 2243-51. PMID 18713838 DOI: 10.1093/Carcin/Bgn199 |
0.695 |
|
| 2008 |
Neil JR, Schiemann WP. Altered TAB1:I kappaB kinase interaction promotes transforming growth factor beta-mediated nuclear factor-kappaB activation during breast cancer progression. Cancer Research. 68: 1462-70. PMID 18316610 DOI: 10.1158/0008-5472.Can-07-3094 |
0.863 |
|
| 2008 |
Galliher-Beckley AJ, Schiemann WP. Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta. Carcinogenesis. 29: 244-51. PMID 18174260 DOI: 10.1093/Carcin/Bgm245 |
0.658 |
|
| 2007 |
Albig AR, Roy TG, Becenti DJ, Schiemann WP. Transcriptome analysis of endothelial cell gene expression induced by growth on matrigel matrices: identification and characterization of MAGP-2 and lumican as novel regulators of angiogenesis. Angiogenesis. 10: 197-216. PMID 17632767 DOI: 10.1007/S10456-007-9075-Z |
0.376 |
|
| 2007 |
Schiemann WP. Targeted TGF-beta chemotherapies: friend or foe in treating human malignancies? Expert Review of Anticancer Therapy. 7: 609-11. PMID 17492924 DOI: 10.1586/14737140.7.5.609 |
0.536 |
|
| 2007 |
Galliher AJ, Schiemann WP. Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion. Cancer Research. 67: 3752-8. PMID 17440088 DOI: 10.1158/0008-5472.Can-06-3851 |
0.84 |
|
| 2006 |
Galliher AJ, Neil JR, Schiemann WP. Role of transforming growth factor-beta in cancer progression. Future Oncology (London, England). 2: 743-63. PMID 17155901 DOI: 10.2217/14796694.2.6.743 |
0.822 |
|
| 2006 |
Freire-de-Lima CG, Xiao YQ, Gardai SJ, Bratton DL, Schiemann WP, Henson PM. Apoptotic cells, through transforming growth factor-beta, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages. The Journal of Biological Chemistry. 281: 38376-84. PMID 17056601 DOI: 10.1074/Jbc.M605146200 |
0.551 |
|
| 2006 |
Galliher AJ, Schiemann WP. Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells. Breast Cancer Research : Bcr. 8: R42. PMID 16859511 DOI: 10.1186/Bcr1524 |
0.844 |
|
| 2006 |
Neil JR, Galliher AJ, Schiemann WP. TGF-beta in cancer and other diseases. Future Oncology (London, England). 2: 185-9. PMID 16563087 DOI: 10.2217/14796694.2.2.185 |
0.79 |
|
| 2006 |
Albig AR, Neil JR, Schiemann WP. Fibulins 3 and 5 antagonize tumor angiogenesis in vivo. Cancer Research. 66: 2621-9. PMID 16510581 DOI: 10.1158/0008-5472.Can-04-4096 |
0.792 |
|
| 2005 |
Albig AR, Schiemann WP. Fibulin-5 function during tumorigenesis. Future Oncology (London, England). 1: 23-35. PMID 16555973 DOI: 10.1517/14796694.1.1.23 |
0.445 |
|
| 2005 |
Sokol JP, Neil JR, Schiemann BJ, Schiemann WP. The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta. Breast Cancer Research : Bcr. 7: R844-53. PMID 16168131 DOI: 10.1186/Bcr1312 |
0.869 |
|
| 2005 |
Albig AR, Schiemann WP. Identification and characterization of regulator of G protein signaling 4 (RGS4) as a novel inhibitor of tubulogenesis: RGS4 inhibits mitogen-activated protein kinases and vascular endothelial growth factor signaling. Molecular Biology of the Cell. 16: 609-25. PMID 15548600 DOI: 10.1091/Mbc.E04-06-0479 |
0.412 |
|
| 2004 |
Albig AR, Schiemann WP. Fibulin-5 antagonizes vascular endothelial growth factor (VEGF) signaling and angiogenic sprouting by endothelial cells. Dna and Cell Biology. 23: 367-79. PMID 15231070 DOI: 10.1089/104454904323145254 |
0.417 |
|
| 2004 |
Cosgrove GP, Brown KK, Schiemann WP, Serls AE, Parr JE, Geraci MW, Schwarz MI, Cool CD, Worthen GS. Pigment epithelium-derived factor in idiopathic pulmonary fibrosis: A role in aberrant angiogenesis American Journal of Respiratory and Critical Care Medicine. 170: 242-251. PMID 15117744 DOI: 10.1164/Rccm.200308-1151Oc |
0.476 |
|
| 2004 |
Schiemann WP, Rotzer D, Pfeifer WM, Levi E, Rai KR, Knaus P, Kadin ME. Transforming growth factor-beta (TGF-beta)-resistant B cells from chronic lymphocytic leukemia patients contain recurrent mutations in the signal sequence of the type I TGF-beta receptor. Cancer Detection and Prevention. 28: 57-64. PMID 15041079 DOI: 10.1016/J.Cdp.2003.11.001 |
0.551 |
|
| 2004 |
Sokol JP, Schiemann WP. Cystatin C antagonizes transforming growth factor beta signaling in normal and cancer cells. Molecular Cancer Research : McR. 2: 183-95. PMID 15037657 |
0.597 |
|
| 2004 |
Ibarrola N, Kratchmarova I, Nakajima D, Schiemann WP, Moustakas A, Pandey A, Mann M. Cloning of a novel signaling molecule, AMSH-2, that potentiates transforming growth factor beta signaling. Bmc Cell Biology. 5: 2. PMID 14728725 DOI: 10.1186/1471-2121-5-2 |
0.579 |
|
| 2003 |
Schiemann BJ, Neil JR, Schiemann WP. SPARC inhibits epithelial cell proliferation in part through stimulation of the transforming growth factor-beta-signaling system. Molecular Biology of the Cell. 14: 3977-88. PMID 14517312 DOI: 10.1091/Mbc.E03-01-0001 |
0.852 |
|
| 2002 |
Schiemann WP, Blobe GC, Kalume DE, Pandey A, Lodish HF. Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. The Journal of Biological Chemistry. 277: 27367-77. PMID 12021267 DOI: 10.1074/Jbc.M200148200 |
0.646 |
|
| 2002 |
Xiao YQ, Malcolm K, Worthen GS, Gardai S, Schiemann WP, Fadok VA, Bratton DL, Henson PM. Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta. The Journal of Biological Chemistry. 277: 14884-93. PMID 11842088 DOI: 10.1074/Jbc.M111718200 |
0.596 |
|
| 2001 |
Perlman R, Schiemann WP, Brooks MW, Lodish HF, Weinberg RA. TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation Nature Cell Biology. 3: 708-714. PMID 11483955 DOI: 10.1038/35087019 |
0.616 |
|
| 2001 |
Blobe GC, Schiemann WP, Pepin MC, Beauchemin M, Moustakas A, Lodish HF, O'Connor-McCourt MD. Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor β Receptor in Regulating Transforming Growth Factor β Signaling Journal of Biological Chemistry. 276: 24627-24637. PMID 11323414 DOI: 10.1074/Jbc.M100188200 |
0.429 |
|
| 2000 |
Gibson RM, Schiemann WP, Prichard LB, Reno JM, Ericsson LH, Nathanson NM. Phosphorylation of human gp130 at Ser-782 adjacent to the Di-leucine internalization motif. Effects on expression and signaling. The Journal of Biological Chemistry. 275: 22574-82. PMID 10811661 DOI: 10.1074/jbc.M907658199 |
0.458 |
|
| 2000 |
Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor β in human disease New England Journal of Medicine. 342: 1350-1358. PMID 10793168 DOI: 10.1056/Nejm200005043421807 |
0.47 |
|
| 1999 |
Schiemann WP, Pfeifer WM, Levi E, Kadin ME, Lodish HF. A Deletion in the Gene for Transforming Growth Factor β Type I Receptor Abolishes Growth Regulation by Transforming Growth Factor β in a Cutaneous T-Cell Lymphoma Blood. 94: 2854-2861. DOI: 10.1182/Blood.V94.8.2854.420K07_2854_2861 |
0.489 |
|
| 1997 |
Schiemann WP, Bartoe JL, Nathanson NM. Box 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at Ras. The Journal of Biological Chemistry. 272: 16631-6. PMID 9195977 DOI: 10.1074/Jbc.272.26.16631 |
0.755 |
|
| 1995 |
Schiemann WP, Graves LM, Baumann H, Morella KK, Gearing DP, Nielsen MD, Krebs EG, Nathanson NM. Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation. Proceedings of the National Academy of Sciences of the United States of America. 92: 5361-5. PMID 7777512 DOI: 10.1073/Pnas.92.12.5361 |
0.497 |
|
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