James DiRenzo - Publications

Affiliations: 
Pharmacology and Toxicology Dartmouth College, Hanover, NH, United States 
Area:
Molecular Biology, Cell Biology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Feng WW, Wilkins O, Bang S, Ung M, Li J, An J, Del Genio C, Canfield K, DiRenzo J, Wells W, Gaur A, Robey RB, Guo JY, Powles RL, Sotiriou C, et al. CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies. Cell Reports. 29: 3405-3420.e5. PMID 31825825 DOI: 10.1016/J.Celrep.2019.11.008  0.37
2015 Balboni AL, Cherukuri P, Ung M, DeCastro AJ, Cheng C, DiRenzo J. p53 and ΔNp63α Coregulate the Transcriptional and Cellular Response to TGFβ and BMP Signals. Molecular Cancer Research : McR. 13: 732-42. PMID 25700283 DOI: 10.1158/1541-7786.Mcr-14-0152-T  0.788
2015 DeCastro AJ, Cherukuri P, Balboni A, DiRenzo J. ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to regulate breast cancer stem cell activity and chemotaxis. Molecular Cancer Therapeutics. 14: 225-35. PMID 25376609 DOI: 10.1158/1535-7163.Mct-14-0194  0.806
2014 Khaleel SS, Andrews EH, Ung M, DiRenzo J, Cheng C. E2F4 regulatory program predicts patient survival prognosis in breast cancer. Breast Cancer Research : Bcr. 16: 486. PMID 25440089 DOI: 10.1186/S13058-014-0486-7  0.301
2014 Sverrisson EF, Zens MS, Fei DL, Andrews A, Schned A, Robbins D, Kelsey KT, Li H, DiRenzo J, Karagas MR, Seigne JD. Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer. Urologic Oncology. 32: 539-45. PMID 24856810 DOI: 10.1016/J.Urolonc.2014.03.006  0.41
2014 Busch AM, Galimberti F, Nehls KE, Roengvoraphoj M, Sekula D, Li B, Guo Y, Direnzo J, Fiering SN, Spinella MJ, Robbins DJ, Memoli VA, Freemantle SJ, Dmitrovsky E. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biology & Therapy. 15: 463-72. PMID 24496080 DOI: 10.4161/Cbt.27821  0.486
2014 DeCastro AJ, DiRenzo J. miRNA function and modulation in stem cells and cancer stem cells Microrna Diagnostics and Therapeutics. 1. DOI: 10.2478/Micrnat-2014-0004  0.778
2013 Dunphy KA, Seo JH, Kim DJ, Roberts AL, Tao L, DiRenzo J, Balboni AL, Crisi GM, Hagen MJ, Chandrasekaran T, Gauger KJ, Schneider SS, Jerry DJ. Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation. Cancer Cell International. 13: 74. PMID 23883065 DOI: 10.1186/1475-2867-13-74  0.794
2013 Ma T, Galimberti F, Erkmen CP, Memoli V, Chinyengetere F, Sempere L, Beumer JH, Anyang BN, Nugent W, Johnstone D, Tsongalis GJ, Kurie JM, Li H, Direnzo J, Guo Y, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Molecular Cancer Therapeutics. 12: 1545-55. PMID 23686769 DOI: 10.1158/1535-7163.Mct-12-0933  0.342
2013 DeCastro AJ, Dunphy KA, Hutchinson J, Balboni AL, Cherukuri P, Jerry DJ, DiRenzo J. MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition. Cell Death & Disease. 4: e514. PMID 23449450 DOI: 10.1038/Cddis.2013.37  0.74
2013 Balboni AL, Hutchinson JA, DeCastro AJ, Cherukuri P, Liby K, Sporn MB, Schwartz GN, Wells WA, Sempere LF, Yu PB, DiRenzo J. ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells. Cancer Research. 73: 1020-30. PMID 23243027 DOI: 10.1158/0008-5472.Can-12-2862  0.771
2012 Cherukuri P, DeCastro AJ, Balboni AL, Downey SL, Liu JY, Hutchinson JA, DiRenzo J. Phosphorylation of ΔNp63α via a novel TGFβ/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGFβ. Plos One. 7: e50066. PMID 23166821 DOI: 10.1371/Journal.Pone.0050066  0.74
2012 Dorosko SM, Cherukuri P, Direnzo J. Unanticipated reversal of polarity in primary human mammospheres cultured in ultra-low attachment plates. Journal of Pharmaceutical Sciences. 101: 4666-8. PMID 22965666 DOI: 10.1002/Jps.23314  0.409
2012 Danilov AV, Srivastava A, Feofanova EV, Humphries LA, Direnzo J, Korc M. Abstract 3076: p53 homologue p63 trans-activates epidermal growth factor (EGF) receptor and 14-3-3α and thus promotes tumorigenesis and chemoresistance in pancreatic cancer Cancer Research. 72: 3076-3076. DOI: 10.1158/1538-7445.Am2012-3076  0.46
2011 Dragnev KH, Ma T, Galimberti F, Erkmen CP, Memoli V, Nugent W, Rigas JR, Johnstone D, Frandsen A, Simeone S, Czum J, Li H, DiRenzo J, Freemantle S, Dmitrovsky E. A window-of-opportunity trial of vorinostat (V) in patients with resectable non-small cell lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 7062. PMID 28020374 DOI: 10.1200/Jco.2011.29.15_Suppl.7062  0.339
2011 Danilov AV, Neupane D, Nagaraja AS, Feofanova EV, Humphries LA, DiRenzo J, Korc M. DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance. Plos One. 6: e26815. PMID 22053213 DOI: 10.1371/Journal.Pone.0026815  0.523
2011 Kent S, Hutchinson J, Balboni A, Decastro A, Cherukuri P, Direnzo J. ΔNp63α promotes cellular quiescence via induction and activation of Notch3. Cell Cycle (Georgetown, Tex.). 10: 3111-8. PMID 21912215 DOI: 10.4161/Cc.10.18.17300  0.707
2011 Collins R, Kaur P, Danilova O, Direnzo J, Danilov AV. p53 Homolog TAp63 elicits apoptosis in Chronic Lymphocytic Leukemia (CLL) B-Cells, Blood. 118: 3894-3894. DOI: 10.1182/Blood.V118.21.3894.3894  0.43
2011 Ma T, Galimberti F, Erkmen CP, Memoli V, Nugent W, Rigas J, Johnstone D, Li H, DiRenzo J, Freemantle S, Dragnev K, Dmitrovsky E. Abstract 342: Murine transgenic lung cancer models guide a proof of principle histone deacetylase inhibitor trial in lung cancer patients Cancer Research. 71: 342-342. DOI: 10.1158/1538-7445.Am2011-342  0.339
2011 Danilov A, Neupane D, DiRenzo J, Korc M. Abstract 223: ΔNp63α, a p53 family member protein, promotes tumor progression in pancreatic cancer Cancer Research. 71: 223-223. DOI: 10.1158/1538-7445.Am2011-223  0.479
2011 Collins R, Kaur P, Danilova O, Direnzo J, Danilov AV. 2.47 p53 Homolog p63 Promotes Apoptosis and Chemosensitivity in Chronic Lymphocytic Leukemia B-Cells Clinical Lymphoma Myeloma and Leukemia. 11: S189. DOI: 10.1016/J.Clml.2011.09.080  0.301
2010 Craig AL, Holcakova J, Finlan LE, Nekulova M, Hrstka R, Gueven N, DiRenzo J, Smith G, Hupp TR, Vojtesek B. DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation. Molecular Cancer. 9: 195. PMID 20663147 DOI: 10.1186/1476-4598-9-195  0.481
2010 Liu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, Demidenko E, Korc M, Shi W, Preis M, Dragnev KH, Li H, Direnzo J, Bak M, Freemantle SJ, et al. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. The Journal of Clinical Investigation. 120: 1298-309. PMID 20237410 DOI: 10.1172/Jci39566  0.353
2010 Fei DL, Li H, Kozul CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ. Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. Cancer Research. 70: 1981-8. PMID 20179202 DOI: 10.1158/0008-5472.Can-09-2898  0.43
2010 Liu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, Demidenko E, Korc M, Shi W, Preis M, Dragnev KH, Liu H, DiRenzo J, Bak M, Kauppinen S, et al. Abstract 5698: MicroRNA-31 acts as an oncomir in lung cancer by repressing specific tumor suppressors Cancer Research. 70: 5698-5698. DOI: 10.1158/1538-7445.Am10-5698  0.346
2009 Harmes DC, DiRenzo J. Cellular quiescence in mammary stem cells and breast tumor stem cells: got testable hypotheses? Journal of Mammary Gland Biology and Neoplasia. 14: 19-27. PMID 19240987 DOI: 10.1007/S10911-009-9111-2  0.817
2008 Li N, Singh S, Cherukuri P, Li H, Yuan Z, Ellisen LW, Wang B, Robbins D, DiRenzo J. Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells. Stem Cells (Dayton, Ohio). 26: 1253-64. PMID 18292212 DOI: 10.1634/Stemcells.2007-0691  0.581
2008 Liu X, Sempere L, Galimberti F, Freemantle S, Black C, Fiering S, Cole C, Dragnev K, Memoli V, Korc M, Li H, DiRenzo J, Bak M, Kauppinen S, Dmitrovsky E. Abstract A135: Uncovering tumor suppressive and oncogenic microRNAs in lung cancer Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A135  0.343
2007 Li H, Cherukuri P, Li N, Cowling V, Spinella M, Cole M, Godwin AK, Wells W, DiRenzo J. Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors. Cancer Research. 67: 501-10. PMID 17234757 DOI: 10.1158/0008-5472.Can-05-4571  0.487
2006 Nakuci E, Mahner S, Direnzo J, ElShamy WM. BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells. Experimental Cell Research. 312: 3120-31. PMID 16860316 DOI: 10.1016/J.Yexcr.2006.06.021  0.491
2006 Li N, Li H, Cherukuri P, Farzan S, Harmes DC, DiRenzo J. TA-p63-gamma regulates expression of DeltaN-p63 in a manner that is sensitive to p53. Oncogene. 25: 2349-59. PMID 16331262 DOI: 10.1038/Sj.Onc.1209270  0.758
2005 Kerley-Hamilton JS, Pike AM, Li N, DiRenzo J, Spinella MJ. A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinoma. Oncogene. 24: 6090-100. PMID 15940259 DOI: 10.1038/Sj.Onc.1208755  0.473
2003 Harmes DC, Bresnick E, Lubin EA, Watson JK, Heim KE, Curtin JC, Suskind AM, Lamb J, DiRenzo J. Positive and negative regulation of ΔN-p63 promoter activity by p53 and ΔN-p63-α contributes to differential regulation of p53 target genes Oncogene. 22: 7607-7616. PMID 14576823 DOI: 10.1038/Sj.Onc.1207129  0.784
2002 DiRenzo J, Signoretti S, Nakamura N, Rivera-Gonzalez R, Sellers W, Loda M, Brown M. Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line. Cancer Research. 62: 89-98. PMID 11782364  0.573
2000 Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription Cell. 103: 843-852. PMID 11136970 DOI: 10.1016/S0092-8674(00)00188-4  0.718
2000 DiRenzo J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M. BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. Molecular and Cellular Biology. 20: 7541-9. PMID 11003650 DOI: 10.1128/Mcb.20.20.7541-7549.2000  0.712
2000 DiRenzo J, Rivera-Gonzalez R, Brown M. Mammary epithelial cells immortalized by over-expression of the catalytic subunit of human telomerase may represent a model for mammary epithelial differentiation Breast Cancer Research. 2. DOI: 10.1186/Bcr121  0.601
1999 McMahon C, Suthiphongchai T, DiRenzo J, Ewen ME. P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor. Proceedings of the National Academy of Sciences of the United States of America. 96: 5382-7. PMID 10318892 DOI: 10.1073/Pnas.96.10.5382  0.394
1999 Shim WS, DiRenzo J, DeCaprio JA, Santen RJ, Brown M, Jeng MH. Segregation of steroid receptor coactivator-1 from steroid receptors in mammary epithelium. Proceedings of the National Academy of Sciences of the United States of America. 96: 208-13. PMID 9874797 DOI: 10.1073/Pnas.96.1.208  0.596
1997 Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J, Pestell RG, Hinds PW, Dowdy SF, Brown M, Ewen ME. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Molecular and Cellular Biology. 17: 5338-47. PMID 9271411 DOI: 10.1128/Mcb.17.9.5338  0.566
1997 DiRenzo J, Söderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Hörlein A, Rosenfeld MG, Glass CK. Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors. Molecular and Cellular Biology. 17: 2166-76. PMID 9121466 DOI: 10.1128/Mcb.17.4.2166  0.345
1996 Hanstein B, Eckner R, DiRenzo J, Halachmi S, Liu H, Searcy B, Kurokawa R, Brown M. p300 is a component of an estrogen receptor coactivator complex Proceedings of the National Academy of Sciences of the United States of America. 93: 11540-11545. PMID 8876171 DOI: 10.1073/Pnas.93.21.11540  0.594
1994 Kurokawa R, DiRenzo J, Boehm M, Sugarman J, Gloss B, Rosenfeld MG, Heyman RA, Glass CK. Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature. 371: 528-31. PMID 7935766 DOI: 10.1038/371528A0  0.32
1991 Glass CK, DiRenzo J, Kurokawa R, Han ZH. Regulation of gene expression by retinoic acid receptors. Dna and Cell Biology. 10: 623-38. PMID 1661598 DOI: 10.1089/Dna.1991.10.623  0.318
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