Pravin B. Sehgal - Publications

Affiliations: 
New York Medical College, New York, NY, United States 
Area:
Cell Biology, Molecular Biology
Website:
https://www.nymc.edu/faculty/directory/by-name/seghal-pravin/

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Sehgal PB, Yuan H, Jin Y. Rapid Reversible Osmoregulation of Cytoplasmic Biomolecular Condensates of Human Interferon-α-Induced Antiviral MxA GTPase. International Journal of Molecular Sciences. 23. PMID 36361529 DOI: 10.3390/ijms232112739  0.301
2020 Sehgal PB, Westley J, Lerea KM, DiSenso-Browne S, Etlinger JD. Biomolecular condensates in cell biology and virology: Phase-separated membraneless organelles (MLOs). Analytical Biochemistry. 597: 113691. PMID 32194074 DOI: 10.1016/J.Ab.2020.113691  0.339
2019 Davis D, Yuan H, Liang FX, Yang YM, Westley J, Petzold C, Dancel-Manning K, Deng Y, Sall J, Sehgal PB. Human antiviral protein MxA forms novel metastable membrane-less cytoplasmic condensates exhibiting rapid reversible tonicity-driven phase transitions. Journal of Virology. PMID 31484749 DOI: 10.1128/Jvi.01014-19  0.346
2019 Sehgal PB. Biomolecular condensates in cancer cell biology: interleukin-6-induced cytoplasmic and nuclear STAT3/PY-STAT3 condensates in hepatoma cells. Contemporary Oncology (Poznan, Poland). 23: 16-22. PMID 31061632 DOI: 10.5114/Wo.2019.83018  0.319
2018 Davis D, Yuan H, Yang YM, Liang FX, Sehgal PB. Interferon-α-induced cytoplasmic MxA structures in hepatoma Huh7 and primary endothelial cells. Contemporary Oncology (Poznan, Poland). 22: 86-94. PMID 30150884 DOI: 10.5114/Wo.2018.76149  0.358
2016 Yuan H, Sehgal PB. MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9). Plos One. 11: e0166382. PMID 27875556 DOI: 10.1371/Journal.Pone.0166382  0.344
2013 Lee JE, Yuan H, Liang FX, Sehgal PB. Nitric oxide scavenging causes remodeling of the endoplasmic reticulum, Golgi apparatus and mitochondria in pulmonary arterial endothelial cells. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 33: 64-73. PMID 23770576 DOI: 10.1016/J.Niox.2013.06.005  0.308
2013 Khan R, Lee JE, Yang YM, Liang FX, Sehgal PB. Live-cell imaging of the association of STAT6-GFP with mitochondria. Plos One. 8: e55426. PMID 23383189 DOI: 10.1371/Journal.Pone.0055426  0.303
2013 Lee JE, Yang YM, Yuan H, Sehgal PB. Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs. American Journal of Physiology. Cell Physiology. 304: C312-23. PMID 23151802 DOI: 10.1152/Ajpcell.00311.2012  0.302
2012 Lee JE, Yang YM, Liang FX, Gough DJ, Levy DE, Sehgal PB. Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function. American Journal of Physiology. Cell Physiology. 302: C804-20. PMID 22159083 DOI: 10.1152/Ajpcell.00379.2011  0.363
2011 Lee JE, Patel K, Almodóvar S, Tuder RM, Flores SC, Sehgal PB. Dependence of Golgi apparatus integrity on nitric oxide in vascular cells: implications in pulmonary arterial hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1141-58. PMID 21217069 DOI: 10.1152/Ajpheart.00767.2010  0.329
2008 Zaiman AL, Podowski M, Medicherla S, Gordy K, Xu F, Zhen L, Shimoda LA, Neptune E, Higgins L, Murphy A, Chakravarty S, Protter A, Sehgal PB, Champion HC, Tuder RM. Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. 177: 896-905. PMID 18202349 DOI: 10.1164/Rccm.200707-1083Oc  0.311
2008 BHARDWAJ N, SANTHANAM U, LAU LL, TATTER SB, GHRAYEB J, RIVELIS M, STEINMAN RM, SEHGAL PB, MAY LT. Identification and Characterization of Interleukin-6/Interferon-β2 in Synovial Effusions of Patients with Rheumatoid Arthritis and Other Arthritides Annals of the New York Academy of Sciences. 557: 550-551. DOI: 10.1111/J.1749-6632.1989.Tb24062.X  0.396
2008 RAY A, TATTER SB, SANTHANAM U, HELFGOTT DC, MAY LT, SEHGAL PB. Regulation of Expression of Interleukin-6 Annals of the New York Academy of Sciences. 557: 353-362. DOI: 10.1111/J.1749-6632.1989.Tb24028.X  0.425
2008 MAY LT, SANTHANAM U, TATTER SB, GHRAYEB J, SEHGAL PB. Multiple Forms of Human Interleukin-6 Annals of the New York Academy of Sciences. 557: 114-121. DOI: 10.1111/J.1749-6632.1989.Tb24004.X  0.487
2006 Jain S, Shah M, Li Y, Vinukonda G, Sehgal PB, Kumar A. Upregulation of human angiotensinogen (AGT) gene transcription by interferon-gamma: involvement of the STAT1-binding motif in the AGT promoter. Biochimica Et Biophysica Acta. 1759: 340-7. PMID 16949687 DOI: 10.1016/J.Bbaexp.2006.07.003  0.372
2006 Mukhopadhyay S, Sehgal PB. Discordant regulatory changes in monocrotaline-induced megalocytosis of lung arterial endothelial and alveolar epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L1216-26. PMID 16414977 DOI: 10.1152/Ajplung.00535.2005  0.344
2006 Shah M, Patel K, Mukhopadhyay S, Xu F, Guo G, Sehgal PB. Membrane-associated STAT3 and PY-STAT3 in the cytoplasm. The Journal of Biological Chemistry. 281: 7302-8. PMID 16407171 DOI: 10.1074/Jbc.M508527200  0.303
2006 Mukhopadhyay S, Shah M, Patel K, Sehgal PB. Monocrotaline pyrrole-induced megalocytosis of lung and breast epithelial cells: Disruption of plasma membrane and Golgi dynamics and an enhanced unfolded protein response. Toxicology and Applied Pharmacology. 211: 209-20. PMID 16000202 DOI: 10.1016/J.Taap.2005.06.004  0.307
2003 Sehgal PB, Kumar V, Guo G, Murray WC. Different patterns of regulation of Tyr-phosphorylated STAT1 and STAT3 in human hepatoma Hep3B cells by the phosphatase inhibitor orthovanadate. Archives of Biochemistry and Biophysics. 412: 242-50. PMID 12667488 DOI: 10.1016/S0003-9861(03)00050-X  0.367
2002 Shah M, Patel K, Fried VA, Sehgal PB. Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes. Preservation of cytokine signaling during fever. The Journal of Biological Chemistry. 277: 45662-9. PMID 12235142 DOI: 10.1074/Jbc.M205935200  0.321
1999 Ndubuisi MI, Guo GG, Fried VA, Etlinger JD, Sehgal PB. Cellular physiology of STAT3: Where's the cytoplasmic monomer? Journal of Biological Chemistry. 274: 25499-25509. PMID 10464281 DOI: 10.1074/Jbc.274.36.25499  0.318
1997 Rayanade RJ, Patel K, Ndubuisi M, Sharma S, Omura S, Etlinger JD, Pine R, Sehgal PB. Proteasome- and p53-dependent Masking of Signal Transducer and Activator of Transcription (STAT) Factors Journal of Biological Chemistry. 272: 4659-4662. PMID 9030516 DOI: 10.1074/Jbc.272.8.4659  0.308
1995 Wang L, Rayanade RJ, Garcia D, Patel K, Pan H, Sehgal PB. Modulation of interleukin-6-induced plasma protein secretion in hepatoma cells by p53 species. Journal of Biological Chemistry. 270: 23159-23165. PMID 7559462 DOI: 10.1074/Jbc.270.39.23159  0.318
1991 Krueger J, Ray A, Tamm I, Sehgal PB. Expression and function of interleukin-6 in epithelial cells. Journal of Cellular Biochemistry. 45: 327-34. PMID 2045425 DOI: 10.1002/Jcb.240450404  0.497
1991 Sehgal PB, Tamm I. Interleukin-6 enhances motility of breast carcinoma cells. Exs. 59: 178-93. PMID 1655518 DOI: 10.1007/978-3-0348-7494-6_12  0.48
1991 Tamm I, Cardinale I, Sehgal PB. Interleukin-6 and 12-O-tetradecanoyl phorbol-13-acetate act synergistically in inducing cell-cell separation and migration of human breast carcinoma cells. Cytokine. 3: 212-23. PMID 1653054 DOI: 10.1016/1043-4666(91)90019-A  0.526
1990 Sehgal PB, Tamm I. Interleukin-6 enhances motility of breast cancer cells. Cancer Investigation. 8: 661-3. PMID 1963346 DOI: 10.3109/07357909009018940  0.411
1989 Tamm I, Cardinale I, Krueger J, Murphy JS, May LT, Sehgal PB. Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells. The Journal of Experimental Medicine. 170: 1649-69. PMID 2553849 DOI: 10.1084/Jem.170.5.1649  0.481
1989 Yan C, Sehgal PB, Tamm I. Signal transduction pathways in the induction of 2',5'-oligoadenylate synthetase gene expression by interferon alpha/beta. Proceedings of the National Academy of Sciences of the United States of America. 86: 2243-7. PMID 2538838 DOI: 10.1073/Pnas.86.7.2243  0.587
1988 Sehgal PB, May LT. Human interferon-beta 2. Journal of Interferon Research. 7: 521-7. PMID 3316421 DOI: 10.1089/jir.1987.7.521  0.339
1987 Kohase M, May LT, Tamm I, Vilcek J, Sehgal PB. A cytokine network in human diploid fibroblasts: interactions of beta-interferons, tumor necrosis factor, platelet-derived growth factor, and interleukin-1. Molecular and Cellular Biology. 7: 273-80. PMID 3494192 DOI: 10.1128/Mcb.7.1.273  0.594
1987 Sehgal PB, May LT, Tamm I, Vilcek J. Human beta 2 interferon and B-cell differentiation factor BSF-2 are identical. Science (New York, N.Y.). 235: 731-2. PMID 3492764 DOI: 10.1126/Science.3492764  0.569
1987 Tamm I, Lin SL, Pfeffer LM, Sehgal PB. Interferons alpha and beta as cellular regulatory molecules. Interferon. 9: 13-74. PMID 3316040  0.528
1987 Sehgal PB, Walther Z, Tamm I. Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187. Proceedings of the National Academy of Sciences of the United States of America. 84: 3663-7. PMID 3108877 DOI: 10.1073/Pnas.84.11.3663  0.606
1987 Kohase M, Henriksen-Destefano D, Sehgal PB, Vilcek J. Dexamethasone inhibits feedback regulation of the mitogenic activity of tumor necrosis factor, interleukin-1, and epidermal growth factor in human fibroblasts. Journal of Cellular Physiology. 132: 271-8. PMID 3040777 DOI: 10.1002/jcp.1041320211  0.33
1987 Helfgott DC, May LT, Sthoeger Z, Tamm I, Sehgal PB. Bacterial lipopolysaccharide (endotoxin) enhances expression and secretion of beta 2 interferon by human fibroblasts. The Journal of Experimental Medicine. 166: 1300-9. PMID 2824651 DOI: 10.1084/Jem.166.5.1300  0.589
1986 Sehgal PB, Zilberstein A, Ruggieri RM, May LT, Ferguson-Smith A, Slate DL, Revel M, Ruddle FH. Human chromosome 7 carries the β2 interferon gene Proceedings of the National Academy of Sciences of the United States of America. 83: 5219-5222. PMID 3014537 DOI: 10.1073/Pnas.83.14.5219  0.382
1986 Kohase M, Henriksen-DeStefano D, May LT, Vilcek J, Sehgal PB. Induction of beta 2-interferon by tumor necrosis factor: a homeostatic mechanism in the control of cell proliferation. Cell. 45: 659-66. PMID 2871942 DOI: 10.1016/0092-8674(86)90780-4  0.415
1985 Sagar AD, Sehgal PB, May LT, Slate DL, Shulman L, Barker PE, Ruddle FH. Interferon-beta-related DNA on human chromosome 4. Somatic Cell and Molecular Genetics. 11: 403-8. PMID 3860969 DOI: 10.1007/BF01534418  0.755
1985 Sagar AD, May LT, Sehgal PB. Increased nuclease sensitivity of the human interferon-alpha 1-related genes and the interferon-beta 1 gene during induction by virus. Journal of Interferon Research. 5: 597-604. PMID 3003210 DOI: 10.1089/jir.1985.5.597  0.767
1985 May LT, Sehgal PB. On the relationship between human interferon alpha 1 and beta 1 genes. Journal of Interferon Research. 5: 521-6. PMID 2414376 DOI: 10.1089/jir.1985.5.521  0.386
1984 Sagar AD, Sehgal PB, May LT, Inouye M, Slate DL, Shulman L, Ruddle FH. Interferon-beta-related DNA is dispersed in the human genome. Science (New York, N.Y.). 223: 1312-5. PMID 6546621 DOI: 10.1126/Science.6546621  0.765
1984 Sehgal PB, Inoue M, Tan YH. Detection of human beta-2 interferon using a radioimmunoassay. Journal of Interferon Research. 4: 63-6. PMID 6538894 DOI: 10.1089/jir.1984.4.63  0.401
1983 May LT, Sehgal PB, LaForge KS, Inouye M. Expression of the native alpha and beta interferon genes in human cells. Virology. 129: 116-26. PMID 6612995 DOI: 10.1016/0042-6822(83)90400-2  0.409
1983 Sehgal PB, May LT, Sagar AD, LaForge KS, Inouye M. Isolation of novel human genomic DNA clones related to human interferon-beta 1 cDNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 3632-6. PMID 6304727 DOI: 10.1073/Pnas.80.12.3632  0.782
1983 Sehgal PB, May LT, LaForge KS, Inouye M. Unusually long mRNA species coding for human alpha and beta interferons. Proceedings of the National Academy of Sciences of the United States of America. 79: 6932-6. PMID 6184718 DOI: 10.1073/Pnas.79.22.6932  0.359
1983 SAGAR AD, MAY LT, SEHGAL PB. DNA Methylation and the Expression of Human Interferon Alpha-1-Related Genes and the Beta-I Gene Journal of Interferon Research. 3: 365-369. DOI: 10.1089/jir.1983.3.365  0.747
1982 Sagar AD, Sehgal PB, Slate DL, Ruddle FH. Multiple human beta interferon genes. The Journal of Experimental Medicine. 156: 744-55. PMID 6180119  0.791
1981 Sehgal PB, Sagar AD, Braude IA. Further heterogeneity of human α interferon mRNA species Science. 214: 803-805. PMID 6170112 DOI: 10.1126/science.6170112  0.747
1981 Sehgal PB. Regulation of the stability of human beta interferon mRNA in poly(l). Poly(C)-induced diploid fibroblasts: anchorage independence of the shutoff mechanism. Virology. 112: 738-45. PMID 6167062 DOI: 10.1016/0042-6822(81)90318-4  0.333
1981 Soreq H, Sagar AD, Sehgal PB. Translational activity and functional stability of human fibroblast beta 1 and beta 2 interferon mRNAs lacking 3'-terminal RNA sequences Proceedings of the National Academy of Sciences of the United States of America. 78: 1741-1745. PMID 6165016 DOI: 10.1073/pnas.78.3.1741  0.771
1981 Sagar AD, Pickering LA, Sussman-Berger P, Stewart WE, Sehgal PB. Heterogeneity of interferon mRNA species from Sendai virus-induced human lymphoblastoid (Namalva) cells and Newcastle disease virus-induced murine fibroblastoid (L) cells. Nucleic Acids Research. 9: 149-60. PMID 6163134  0.783
1980 Sehgal PB, Tamm I. Benzimidazoles and their nucleosides. Antibiotics and Chemotherapy. 27: 93-138. PMID 6996610 DOI: 10.1159/000385391  0.43
1980 Sehgal PB, Tamm I. Synthesis, structure, and function of poly(I).poly(C)-induced human fibroblast interferon mRNA. Annals of the New York Academy of Sciences. 350: 405-12. PMID 6165290 DOI: 10.1111/J.1749-6632.1980.Tb20642.X  0.53
1980 Sehgal PB, Sagar AD. Heterogeneity of poly(I).poly(C)-induced human fibroblast interferon mRNA species Nature. 288: 95-97. PMID 6159547 DOI: 10.1038/288095a0  0.759
1980 Sehgal PB, Tamm I. The transcription unit for poly(I) . poly(C)-induced human fibroblast interferon messenger RNA. Virology. 102: 245-9. PMID 6154374 DOI: 10.1016/0042-6822(80)90090-2  0.561
1979 Sehgal PB, Tamm I. Two mechanisms contribute to the superinduction of poly(I).poly(C)-induced human fibroblast interferon production. Virology. 92: 240-4. PMID 419694 DOI: 10.1016/0042-6822(79)90230-7  0.548
1979 Tamm I, Sehgal PB. Interferons. The American Journal of Medicine. 66: 3-5. PMID 283690 DOI: 10.1016/0002-9343(79)90472-8  0.497
1978 Sehgal PB, Lyles DS, Tamm I. Superinduction of human fibroblast interferon production: further evidence for increased stability of interferon mRNA. Virology. 89: 186-98. PMID 685176 DOI: 10.1016/0042-6822(78)90051-X  0.549
1978 Sehgal PB, Tamm I. Halogenated benzimidazole ribosides, Novel inhibitors of RNA synthesis. Biochemical Pharmacology. 27: 2475-85. PMID 365184 DOI: 10.1016/0006-2952(78)90313-1  0.458
1978 Tamm I, Sehgal PB. Halobenzimidazole ribosides and RNA synthesis of cells and viruses. Advances in Virus Research. 22: 187-258. PMID 345776 DOI: 10.1016/S0065-3527(08)60775-7  0.501
1978 Sehgal PB, Soreq H, Tamm I. Does 3'-terminal poly(A) stabilize human fibroblast interferon mRNA in oocytes of Xenopus laevis? Proceedings of the National Academy of Sciences of the United States of America. 75: 5030-3. PMID 283411 DOI: 10.1073/Pnas.75.10.5030  0.554
1977 Tamm I, Sehgal PB. A comparative study of the effects of certain halogenated benzimidazole ribosides on RNA synthesis, cell proliferation, and interferon production. The Journal of Experimental Medicine. 145: 344-56. PMID 833544 DOI: 10.1084/Jem.145.2.344  0.552
1977 Sehgal PB, Dobberstein B, Tamm I. Interferon messenger RNA content of human fibroblasts during induction, shutoff, and superinduction of interferon production. Proceedings of the National Academy of Sciences of the United States of America. 74: 3409-13. PMID 269400 DOI: 10.1073/Pnas.74.8.3409  0.581
1976 Sehgal PB, Tamm I, Vilcek J. Regulation of human interferon production. II. Inhibition of interferon messenger RNA synthesis by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole. Virology. 70: 542-4. PMID 1266051 DOI: 10.1016/0042-6822(76)90295-6  0.566
1976 Sehgal PB, Tamm I, Vilcek J. Regulation of human interferon production. I. Superinduction by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole. Virology. 70: 532-41. PMID 1266050 DOI: 10.1016/0042-6822(76)90294-4  0.559
1976 Sehgal PB, Tamm I, Vilcek J. On the mechanism of enhancement of human interferon production by actinomycin D and cycloheximide. Virology. 70: 256-9. PMID 1258381 DOI: 10.1016/0042-6822(76)90267-1  0.512
1976 Sehgal PB, Darnell JE, Tamm I. The inhibition by DRB (5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole) of hnRNA and mRNA production in HeLa cells. Cell. 9: 473-80. PMID 1086720 DOI: 10.1016/0092-8674(76)90092-1  0.559
1976 Sehgal PB, Tamm I. An evaluation of messenger RNA competition in the shutoff of human interferon production. Proceedings of the National Academy of Sciences of the United States of America. 73: 1621-5. PMID 1064033 DOI: 10.1073/Pnas.73.5.1621  0.525
1976 Sehgal PB, Derman E, Molloy GR, Tamm I, Darnell JE. 5,6-Dichloro-1-Beta-D-ribofuranosylbenzimidazole inhibits initiation of nuclear heterogeneous RNA chains in HeLa cells. Science (New York, N.Y.). 194: 431-3. PMID 982026 DOI: 10.1126/Science.982026  0.514
1975 Sehgal PB, Tamm I, Vilcek J. Human interferon production: superinduction by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole. Science (New York, N.Y.). 190: 282-4. PMID 1179208 DOI: 10.1126/Science.1179208  0.577
1975 Sehgal PB, Tamm I, Vilcek J. Enhancement of human interferon production by neutral red and chloroquine: analysis of inhibition of protein degradation and macromolecular synthesis. The Journal of Experimental Medicine. 142: 1283-1300. PMID 53261 DOI: 10.1084/Jem.142.5.1283  0.501
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