Year |
Citation |
Score |
2023 |
Normandin K, Coulombe-Huntington J, St-Denis C, Bernard A, Bourouh M, Bertomeu T, Tyers M, Archambault V. Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations. Plos Genetics. 19: e1010903. PMID 37639469 DOI: 10.1371/journal.pgen.1010903 |
0.306 |
|
2021 |
Sachamitr P, Ho JC, Ciamponi FE, Ba-Alawi W, Coutinho FJ, Guilhamon P, Kushida MM, Cavalli FMG, Lee L, Rastegar N, Vu V, Sánchez-Osuna M, Coulombe-Huntington J, Kanshin E, Whetstone H, ... ... Tyers M, et al. PRMT5 inhibition disrupts splicing and stemness in glioblastoma. Nature Communications. 12: 979. PMID 33579912 DOI: 10.1038/s41467-021-21204-5 |
0.477 |
|
2020 |
Oughtred R, Rust J, Chang C, Breitkreutz BJ, Stark C, Willems A, Boucher L, Leung G, Kolas N, Zhang F, Dolma S, Coulombe-Huntington J, Chatr-Aryamontri A, Dolinski K, Tyers M. The BioGRID database: A comprehensive biomedical resource of curated protein, genetic and chemical interactions. Protein Science : a Publication of the Protein Society. PMID 33070389 DOI: 10.1002/pro.3978 |
0.767 |
|
2020 |
Benslimane Y, Bertomeu T, Coulombe-Huntington J, McQuaid M, Sánchez-Osuna M, Papadopoli D, Avizonis D, Russo MST, Huard C, Topisirovic I, Wurtele H, Tyers M, Harrington L. Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells. Molecular Cell. PMID 32755594 DOI: 10.1016/J.Molcel.2020.07.010 |
0.324 |
|
2020 |
Black L, Tollis S, Fu G, Fiche JB, Dorsey S, Cheng J, Ghazal G, Notley S, Crevier B, Bigness J, Nollmann M, Tyers M, Royer CA. G1/S transcription factors assemble in increasing numbers of discrete clusters through G1 phase. The Journal of Cell Biology. 219. PMID 32744610 DOI: 10.1083/Jcb.202003041 |
0.301 |
|
2020 |
Michealraj KA, Kumar SA, Kim LJY, Cavalli FMG, Przelicki D, Wojcik JB, Delaidelli A, Bajic A, Saulnier O, MacLeod G, Vellanki RN, Vladoiu MC, Guilhamon P, Ong W, Lee JJY, ... ... Tyers M, et al. Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma. Cell. PMID 32445698 DOI: 10.1016/J.Cell.2020.04.047 |
0.499 |
|
2020 |
Szewczyk MM, Ishikawa Y, Organ S, Sakai N, Li F, Halabelian L, Ackloo S, Couzens AL, Eram M, Dilworth D, Fukushi H, Harding R, Dela Seña CC, Sugo T, Hayashi K, ... Tyers M, et al. Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nature Communications. 11: 2396. PMID 32409666 DOI: 10.1038/S41467-020-16271-Z |
0.33 |
|
2020 |
Jacques S, van der Sloot AM, Huard C, Coulombe-Huntington J, Tsao S, Tollis S, Bertomeu T, Culp EJ, Pallant D, Cook MA, Bonneil E, Thibault P, Wright GD, Tyers M. Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development. Genetics. PMID 32094149 DOI: 10.1534/Genetics.119.302851 |
0.332 |
|
2019 |
Hill S, Reichermeier K, Scott DC, Samentar L, Coulombe-Huntington J, Izzi L, Tang X, Ibarra R, Bertomeu T, Moradian A, Sweredoski MJ, Caberoy N, Schulman BA, Sicheri F, Tyers M, et al. Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways. Elife. 8. PMID 31868589 DOI: 10.7554/Elife.51163 |
0.323 |
|
2019 |
Sellam A, Chaillot J, Mallick J, Tebbji F, Richard Albert J, Cook MA, Tyers M. The p38/HOG stress-activated protein kinase network couples growth to division in Candida albicans. Plos Genetics. 15: e1008052. PMID 30921326 DOI: 10.1371/Journal.Pgen.1008052 |
0.423 |
|
2019 |
Dong S, Lau V, Song R, Ierullo M, Esteban E, Wu Y, Sivieng T, Nahal-Bose HK, Gaudinier A, Pasha A, Oughtred R, Dolinski K, Tyers M, Brady SM, Grene R, et al. Proteome-Wide, Structure-Based Prediction of Protein-protein Interactions / New Molecular Interactions Viewer. Plant Physiology. PMID 30679268 DOI: 10.1104/Pp.18.01216 |
0.427 |
|
2018 |
Oughtred R, Stark C, Breitkreutz BJ, Rust J, Boucher L, Chang C, Kolas N, O'Donnell L, Leung G, McAdam R, Zhang F, Dolma S, Willems A, Coulombe-Huntington J, Chatr-Aryamontri A, ... Tyers M, et al. The BioGRID interaction database: 2019 update. Nucleic Acids Research. PMID 30476227 DOI: 10.1093/Nar/Gky1079 |
0.766 |
|
2018 |
Kanshin E, Pascariu M, Tyers M, D'Amours D, Thibault P. A combined enrichment/enzymatic approach to study tightly clustered multi-site phosphorylation on Ser-rich domains. Journal of Proteome Research. PMID 30063138 DOI: 10.1021/Acs.Jproteome.8B00205 |
0.434 |
|
2018 |
Palou R, Dhanaraman T, Marrakchi R, Pascariu M, Tyers M, D'Amours D. Condensin ATPase motifs contribute differentially to the maintenance of chromosome morphology and genome stability. Plos Biology. 16: e2003980. PMID 29949571 DOI: 10.1371/Journal.Pbio.2003980 |
0.31 |
|
2018 |
Dorsey S, Tollis S, Cheng J, Black L, Notley S, Tyers M, Royer CA. G1/S Transcription Factor Copy Number Is a Growth-Dependent Determinant of Cell Cycle Commitment in Yeast. Cell Systems. 6: 539-554.e11. PMID 29792825 DOI: 10.1016/J.Cels.2018.04.012 |
0.315 |
|
2018 |
Baccelli I, Gareau Y, Lehnertz B, Stephane G, Spinella J, Beautrait A, Corneau S, Mayotte N, Boivin I, Girard S, MacRae T, Frechette M, Leveille K, Krosl J, Thiollier C, ... Tyers M, et al. Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia Blood. 132: 910-910. DOI: 10.1182/Blood-2018-99-114525 |
0.308 |
|
2018 |
Simon L, Lavallee V, Bordeleau M, Lehnertz B, MacRae T, Chagraoui J, Spinella J, Boucher G, Bertomeu T, Coulombe-Huntington J, Tyers M, Lemieux S, Marinier A, Hébert J, Sauvageau G. Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids Blood. 132: 4675-4675. DOI: 10.1182/Blood-2018-99-111030 |
0.349 |
|
2017 |
Csizmok V, Montecchio M, Lin H, Tyers M, Sunnerhagen M, Forman-Kay JD. Multivalent Interactions with Fbw7 and Pin1 Facilitate Recognition of c-Jun by the SCFFbw7 Ubiquitin Ligase. Structure (London, England : 1993). PMID 29225075 DOI: 10.1016/J.Str.2017.11.003 |
0.364 |
|
2017 |
Bertomeu T, Coulombe-Huntington J, Chatr-Aryamontri A, Bourdages K, Coyaud E, Raught B, Xia Y, Tyers M. A high resolution genome-wide CRISPR/Cas9 viability screen reveals structural features and contextual diversity of the human cell-essential proteome. Molecular and Cellular Biology. PMID 29038160 DOI: 10.1128/Mcb.00302-17 |
0.381 |
|
2017 |
Schapira M, Tyers M, Torrent M, Arrowsmith CH. WD40 repeat domain proteins: a novel target class? Nature Reviews. Drug Discovery. PMID 29026209 DOI: 10.1038/Nrd.2017.179 |
0.359 |
|
2017 |
Courcelles M, Coulombe-Huntington J, Cossette É, Gingras AC, Thibault P, Tyers M. CLMSVault: a software suite for protein cross-linking mass spectrometry data analysis and visualization. Journal of Proteome Research. PMID 28537071 DOI: 10.1021/Acs.Jproteome.7B00205 |
0.345 |
|
2017 |
Kanshin E, Giguere S, Cheng J, Tyers MD, Thibault P. Machine learning of global phosphoproteomic profiles enables discrimination of direct versus indirect kinase substrates. Molecular & Cellular Proteomics : McP. PMID 28265048 DOI: 10.1074/Mcp.M116.066233 |
0.374 |
|
2017 |
Islamaj Doğan R, Kim S, Chatr-Aryamontri A, Chang CS, Oughtred R, Rust J, Wilbur WJ, Comeau DC, Dolinski K, Tyers M. The BioC-BioGRID corpus: full text articles annotated for curation of protein-protein and genetic interactions. Database : the Journal of Biological Databases and Curation. 2017. PMID 28077563 DOI: 10.1093/Database/Baw147 |
0.408 |
|
2017 |
Csizmok V, Orlicky S, Cheng J, Song J, Bah A, Delgoshaie N, Lin H, Mittag T, Sicheri F, Chan HS, Tyers M, Forman-Kay JD. An allosteric conduit facilitates dynamic multisite substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nature Communications. 8: 13943. PMID 28045046 DOI: 10.1038/Ncomms13943 |
0.35 |
|
2017 |
Grove C, Oughtred R, Lee R, Dolinski K, Tyers M, Sternberg P, Baryshnikova A. The Genetic Interactions Structured Terminology (GIST): A modular approach to classifying and curating quantitative genetic interactions F1000research. 6. DOI: 10.7490/F1000Research.1113923.1 |
0.311 |
|
2017 |
Dorsey SB, Tollis S, Cheng J, Olofsson L, Tyers M, Royer CA. Quantification of Nutrient Dependence of SBF/MBF Transcription Factors Controlling Start in Budding Yeast Biophysical Journal. 112: 279a. DOI: 10.1016/J.Bpj.2016.11.1512 |
0.375 |
|
2016 |
Chatr-Aryamontri A, Oughtred R, Boucher L, Rust J, Chang C, Kolas NK, O'Donnell L, Oster S, Theesfeld C, Sellam A, Stark C, Breitkreutz BJ, Dolinski K, Tyers M. The BioGRID interaction database: 2017 update. Nucleic Acids Research. PMID 27980099 DOI: 10.1093/Nar/Gkw1102 |
0.433 |
|
2016 |
Wildenhain J, Spitzer M, Dolma S, Jarvik N, White R, Roy M, Griffiths E, Bellows DS, Wright GD, Tyers M. Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism. Scientific Data. 3: 160095. PMID 27874849 DOI: 10.1038/Sdata.2016.95 |
0.327 |
|
2016 |
Kim S, Islamaj Doğan R, Chatr-Aryamontri A, Chang CS, Oughtred R, Rust J, Batista-Navarro R, Carter J, Ananiadou S, Matos S, Santos A, Campos D, Oliveira JL, Singh O, Jonnagaddala J, ... ... Tyers M, et al. BioCreative V BioC track overview: collaborative biocurator assistant task for BioGRID. Database : the Journal of Biological Databases and Curation. 2016. PMID 27589962 DOI: 10.1093/Database/Baw121 |
0.326 |
|
2016 |
Dolma S, Selvadurai HJ, Lan X, Lee L, Kushida M, Voisin V, Whetstone H, So M, Aviv T, Park N, Zhu X, Xu C, Head R, Rowland KJ, Bernstein M, ... ... Tyers M, et al. Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells. Cancer Cell. 29: 859-873. PMID 27300435 DOI: 10.1016/J.Ccell.2016.05.002 |
0.656 |
|
2016 |
Liu G, Knight JD, Zhang JP, Tsou CC, Wang J, Lambert JP, Larsen B, Tyers M, Raught B, Bandeira N, Nesvizhskii AI, Choi H, Gingras AC. Data Independent Acquisition analysis in ProHits 4.0. Journal of Proteomics. PMID 27132685 DOI: 10.1016/J.Jprot.2016.04.042 |
0.334 |
|
2016 |
Gorelik M, Orlicky S, Sartori MA, Tang X, Marcon E, Kurinov I, Greenblatt JF, Tyers M, Moffat J, Sicheri F, Sidhu SS. Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976582 DOI: 10.1073/Pnas.1519389113 |
0.393 |
|
2016 |
Oughtred R, Chatr-Aryamontri A, Breitkreutz BJ, Chang CS, Rust JM, Theesfeld CL, Heinicke S, Breitkreutz A, Chen D, Hirschman J, Kolas N, Livstone MS, Nixon J, O'Donnell L, Ramage L, ... Tyers M, et al. BioGRID: A Resource for Studying Biological Interactions in Yeast. Cold Spring Harbor Protocols. 2016: pdb.top080754. PMID 26729913 DOI: 10.1101/Pdb.Top080754 |
0.8 |
|
2016 |
Oughtred R, Chatr-Aryamontri A, Breitkreutz BJ, Chang CS, Rust JM, Theesfeld CL, Heinicke S, Breitkreutz A, Chen D, Hirschman J, Kolas N, Livstone MS, Nixon J, O'Donnell L, Ramage L, ... Tyers M, et al. Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions. Cold Spring Harbor Protocols. 2016: pdb.prot088880. PMID 26729909 DOI: 10.1101/Pdb.Prot088880 |
0.79 |
|
2016 |
Oughtred R, Breitkreutz B, Boucher L, Chang CS, Rust JM, Chatr-aryamontri A, Kolas N, O'Donnell L, Theesfeld CL, Stark C, Dolinski K, Tyers M. The BioGRID interaction database: integration of genetic, protein and chemical interactions and an improved network viewer F1000research. 5. DOI: 10.7490/F1000Research.1111777.1 |
0.4 |
|
2016 |
Dorsey SB, Tollis S, Cheng J, Olofsson L, Tyers M, Royer CA. Quantification of the Nutrient Dependence of Factors Controlling Start in Budding Yeast by 2-Photon Scanning Number and Brightness Biophysical Journal. 110: 141a. DOI: 10.1016/J.Bpj.2015.11.804 |
0.361 |
|
2015 |
Wildenhain J, Spitzer M, Dolma S, Jarvik N, White R, Roy M, Griffiths E, Bellows DS, Wright GD, Tyers M. Prediction of Synergism from Chemical-Genetic Interactions by Machine Learning. Cell Systems. 1: 383-395. PMID 27136353 DOI: 10.1016/J.Cels.2015.12.003 |
0.33 |
|
2015 |
Kanshin E, Tyers M, Thibault P. Sample Collection Method Bias Effects in Quantitative Phosphoproteomics. Journal of Proteome Research. PMID 26040406 DOI: 10.1021/Acs.Jproteome.5B00404 |
0.358 |
|
2015 |
Castonguay E, White SA, Kagansky A, St-Cyr DJ, Castillo AG, Brugger C, White R, Bonilla C, Spitzer M, Earnshaw WC, Schalch T, Ekwall K, Tyers M, Allshire RC. Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing. Molecular and Cellular Biology. 35: 662-74. PMID 25487573 DOI: 10.1128/Mcb.01102-14 |
0.33 |
|
2015 |
Chatr-Aryamontri A, Breitkreutz BJ, Oughtred R, Boucher L, Heinicke S, Chen D, Stark C, Breitkreutz A, Kolas N, O'Donnell L, Reguly T, Nixon J, Ramage L, Winter A, Sellam A, ... Tyers M, et al. The BioGRID interaction database: 2015 update. Nucleic Acids Research. 43: D470-8. PMID 25428363 DOI: 10.1093/Nar/Gku1204 |
0.786 |
|
2014 |
Gohard FH, St-Cyr DJ, Tyers M, Earnshaw WC. Targeting the INCENP IN-box-Aurora B interaction to inhibit CPC activity in vivo. Open Biology. 4: 140163. PMID 25392451 DOI: 10.1098/Rsob.140163 |
0.381 |
|
2014 |
Zeqiraj E, Tang X, Hunter RW, García-Rocha M, Judd A, Deak M, von Wilamowitz-Moellendorff A, Kurinov I, Guinovart JJ, Tyers M, Sakamoto K, Sicheri F. Structural basis for the recruitment of glycogen synthase by glycogenin. Proceedings of the National Academy of Sciences of the United States of America. 111: E2831-40. PMID 24982189 DOI: 10.1073/Pnas.1402926111 |
0.348 |
|
2014 |
Beard PM, Griffiths SJ, Gonzalez O, Haga IR, Pechenick Jowers T, Reynolds DK, Wildenhain J, Tekotte H, Auer M, Tyers M, Ghazal P, Zimmer R, Haas J. A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference. Plos One. 9: e98431. PMID 24901222 DOI: 10.1371/Journal.Pone.0098431 |
0.356 |
|
2014 |
Delgoshaie N, Tang X, Kanshin ED, Williams EC, Rudner AD, Thibault P, Tyers M, Verreault A. Regulation of the histone deacetylase Hst3 by cyclin-dependent kinases and the ubiquitin ligase SCFCdc4. The Journal of Biological Chemistry. 289: 13186-96. PMID 24648511 DOI: 10.1074/Jbc.M113.523530 |
0.377 |
|
2014 |
Spitzer M, Wildenhain J, Rappsilber J, Tyers M. BoxPlotR: a web tool for generation of box plots. Nature Methods. 11: 121-2. PMID 24481215 DOI: 10.1038/Nmeth.2811 |
0.301 |
|
2014 |
Huang H, Ceccarelli DF, Orlicky S, St-Cyr DJ, Ziemba A, Garg P, Plamondon S, Auer M, Sidhu S, Marinier A, Kleiger G, Tyers M, Sicheri F. E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nature Chemical Biology. 10: 156-163. PMID 24316736 DOI: 10.1038/Nchembio.1412 |
0.372 |
|
2014 |
Keszei AF, Tang X, McCormick C, Zeqiraj E, Rohde JR, Tyers M, Sicheri F. Structure of an SspH1-PKN1 complex reveals the basis for host substrate recognition and mechanism of activation for a bacterial E3 ubiquitin ligase. Molecular and Cellular Biology. 34: 362-73. PMID 24248594 DOI: 10.1128/Mcb.01360-13 |
0.362 |
|
2014 |
Dolma S, So M, Voisin V, Zhu X, Head R, Clarke I, Bader G, Tyers M, Dirks P. SC-05 * DOPAMINE RECEPTOR ANTAGONISTS ARE SELECTIVE INHIBITORS OF GLIOBLASTOMA STEM CELLS THROUGH IMPAIRMENT OF AUTOPHAGY Neuro-Oncology. 16: v198-v198. DOI: 10.1093/Neuonc/Nou275.5 |
0.53 |
|
2013 |
Sadowski I, Breitkreutz BJ, Stark C, Su TC, Dahabieh M, Raithatha S, Bernhard W, Oughtred R, Dolinski K, Barreto K, Tyers M. The PhosphoGRID Saccharomyces cerevisiae protein phosphorylation site database: Version 2.0 update Database. 2013. PMID 23674503 DOI: 10.1093/Database/Bat026 |
0.305 |
|
2013 |
Dolinski K, Chatr-Aryamontri A, Tyers M. Systematic curation of protein and genetic interaction data for computable biology. Bmc Biology. 11: 43. PMID 23587305 DOI: 10.1186/1741-7007-11-43 |
0.406 |
|
2013 |
Ernst A, Avvakumov G, Tong J, Fan Y, Zhao Y, Alberts P, Persaud A, Walker JR, Neculai AM, Neculai D, Vorobyov A, Garg P, Beatty L, Chan PK, Juang YC, ... Tyers M, et al. A strategy for modulation of enzymes in the ubiquitin system. Science (New York, N.Y.). 339: 590-5. PMID 23287719 DOI: 10.1126/Science.1230161 |
0.364 |
|
2013 |
Chatr-Aryamontri A, Breitkreutz BJ, Heinicke S, Boucher L, Winter A, Stark C, Nixon J, Ramage L, Kolas N, O'Donnell L, Reguly T, Breitkreutz A, Sellam A, Chen D, Chang C, ... Tyers M, et al. The BioGRID interaction database: 2013 update. Nucleic Acids Research. 41: D816-23. PMID 23203989 DOI: 10.1093/Nar/Gks1158 |
0.777 |
|
2012 |
Liu G, Zhang J, Choi H, Lambert JP, Srikumar T, Larsen B, Nesvizhskii AI, Raught B, Tyers M, Gingras AC. Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit8.16. PMID 22948730 DOI: 10.1002/0471250953.Bi0816S39 |
0.303 |
|
2012 |
Choi H, Liu G, Mellacheruvu D, Tyers M, Gingras AC, Nesvizhskii AI. Analyzing protein-protein interactions from affinity purification-mass spectrometry data with SAINT. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit8.15. PMID 22948729 DOI: 10.1002/0471250953.Bi0815S39 |
0.401 |
|
2012 |
Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, et al. ALDH2 mediates 5-nitrofuran activity in multiple species. Chemistry & Biology. 19: 883-92. PMID 22840776 DOI: 10.1016/J.Chembiol.2012.05.017 |
0.647 |
|
2012 |
Orchard S, Kerrien S, Abbani S, Aranda B, Bhate J, Bidwell S, Bridge A, Briganti L, Brinkman FS, Brinkman F, Cesareni G, Chatr-aryamontri A, Chautard E, Chen C, Dumousseau M, ... Tyers M, et al. Protein interaction data curation: the International Molecular Exchange (IMEx) consortium. Nature Methods. 9: 345-50. PMID 22453911 DOI: 10.1038/Nmeth.1931 |
0.373 |
|
2012 |
Carrillo E, Ben-Ari G, Wildenhain J, Tyers M, Grammentz D, Lee TA. Characterizing the roles of Met31 and Met32 in coordinating Met4-activated transcription in the absence of Met30. Molecular Biology of the Cell. 23: 1928-42. PMID 22438580 DOI: 10.1091/Mbc.E11-06-0532 |
0.335 |
|
2012 |
Tang X, Orlicky S, Mittag T, Csizmok V, Pawson T, Forman-Kay JD, Sicheri F, Tyers M. Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCF Cdc4 ubiquitin ligase Proceedings of the National Academy of Sciences of the United States of America. 109: 3287-3292. PMID 22328159 DOI: 10.1073/Pnas.1116455109 |
0.403 |
|
2012 |
Chou YC, Keszei AFA, Rohde JR, Tyers M, Sicheri F. Conserved structural mechanisms for autoinhibition in IpaH ubiquitin ligases Journal of Biological Chemistry. 287: 268-275. PMID 22065585 DOI: 10.1074/Jbc.M111.316265 |
0.312 |
|
2012 |
Orchard S, Kerrien S, Abbani S, Aranda B, Bhate J, Bidwell S, Bridge A, Briganti L, Brinkman F, Cesareni G, Chatr-Aryamontri A, Chautard E, Chen C, Dumousseau M, Goll J, ... Tyers M, et al. Corrigendum: Protein interaction data curation: The International Molecular Exchange (IMEx) consortium (Nature Methods (2012) 9, (345-350)) Nature Methods. 9: 626. DOI: 10.1038/Nmeth0612-626A |
0.39 |
|
2011 |
Piggott N, Cook MA, Tyers M, Measday V. Genome-wide Fitness Profiles Reveal a Requirement for Autophagy During Yeast Fermentation. G3 (Bethesda, Md.). 1: 353-67. PMID 22384346 DOI: 10.1534/G3.111.000836 |
0.322 |
|
2011 |
Krallinger M, Vazquez M, Leitner F, Salgado D, Chatr-Aryamontri A, Winter A, Perfetto L, Briganti L, Licata L, Iannuccelli M, Castagnoli L, Cesareni G, Tyers M, Schneider G, Rinaldi F, et al. The Protein-Protein Interaction tasks of BioCreative III: classification/ranking of articles and linking bio-ontology concepts to full text. Bmc Bioinformatics. 12: S3. PMID 22151929 DOI: 10.1186/1471-2105-12-S8-S3 |
0.317 |
|
2011 |
Chatr-Aryamontri A, Winter A, Perfetto L, Briganti L, Licata L, Iannuccelli M, Castagnoli L, Cesareni G, Tyers M. Benchmarking of the 2010 BioCreative Challenge III text-mining competition by the BioGRID and MINT interaction databases. Bmc Bioinformatics. 12: S8. PMID 22151178 DOI: 10.1186/1471-2105-12-S8-S8 |
0.347 |
|
2011 |
Huber A, French SL, Tekotte H, Yerlikaya S, Stahl M, Perepelkina MP, Tyers M, Rougemont J, Beyer AL, Loewith R. Sch9 regulates ribosome biogenesis via Stb3, Dot6 and Tod6 and the histone deacetylase complex RPD3L. The Embo Journal. 30: 3052-64. PMID 21730963 DOI: 10.1038/Emboj.2011.221 |
0.402 |
|
2011 |
Aranda B, Blankenburg H, Kerrien S, Brinkman FS, Ceol A, Chautard E, Dana JM, De Las Rivas J, Dumousseau M, Galeota E, Gaulton A, Goll J, Hancock RE, Isserlin R, Jimenez RC, ... Tyers M, et al. PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nature Methods. 8: 528-9. PMID 21716279 DOI: 10.1038/Nmeth.1637 |
0.419 |
|
2011 |
Spitzer M, Griffiths E, Blakely KM, Wildenhain J, Ejim L, Rossi L, De Pascale G, Curak J, Brown E, Tyers M, Wright GD. Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. Molecular Systems Biology. 7: 499. PMID 21694716 DOI: 10.1038/Msb.2011.31 |
0.307 |
|
2011 |
Ceccarelli DF, Tang X, Pelletier B, Orlicky S, Xie W, Plantevin V, Neculai D, Chou YC, Ogunjimi A, Al-Hakim A, Varelas X, Koszela J, Wasney GA, Vedadi M, Dhe-Paganon S, ... Tyers M, et al. An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. Cell. 145: 1075-87. PMID 21683433 DOI: 10.1016/J.Cell.2011.05.039 |
0.354 |
|
2011 |
Winter AG, Wildenhain J, Tyers M. BioGRID REST Service, BiogridPlugin2 and BioGRID WebGraph: new tools for access to interaction data at BioGRID. Bioinformatics (Oxford, England). 27: 1043-4. PMID 21300700 DOI: 10.1093/Bioinformatics/Btr062 |
0.339 |
|
2011 |
Cocklin R, Heyen J, Larry T, Tyers M, Goebl M. New insight into the role of the Cdc34 ubiquitin-conjugating enzyme in cell cycle regulation via Ace2 and Sic1 Genetics. 187: 701-715. PMID 21196523 DOI: 10.1534/Genetics.110.125302 |
0.315 |
|
2011 |
Choi H, Larsen B, Lin ZY, Breitkreutz A, Mellacheruvu D, Fermin D, Qin ZS, Tyers M, Gingras AC, Nesvizhskii AI. SAINT: probabilistic scoring of affinity purification-mass spectrometry data. Nature Methods. 8: 70-3. PMID 21131968 DOI: 10.1038/Nmeth.1541 |
0.772 |
|
2011 |
Liu Q, Larsen B, Ricicova M, Orlicky S, Tekotte H, Tang X, Craig K, Quiring A, Le Bihan T, Hansen C, Sicheri F, Tyers M. SCFCdc4 enables mating type switching in yeast by cyclin-dependent kinase-mediated elimination of the Ash1 transcriptional repressor Molecular and Cellular Biology. 31: 584-598. PMID 21098119 DOI: 10.1128/Mcb.00845-10 |
0.386 |
|
2011 |
Stark C, Breitkreutz BJ, Chatr-Aryamontri A, Boucher L, Oughtred R, Livstone MS, Nixon J, Van Auken K, Wang X, Shi X, Reguly T, Rust JM, Winter A, Dolinski K, Tyers M. The BioGRID Interaction Database: 2011 update. Nucleic Acids Research. 39: D698-704. PMID 21071413 DOI: 10.1093/Nar/Gkq1116 |
0.442 |
|
2011 |
Livstone MS, Breitkreutz B, Stark C, Boucher L, Chatr-Aryamontri A, Oughtred R, Nixon J, Reguly T, Rust J, Winter A, Dolinski K, Tyers M. The BioGRID Interaction Database Nature Precedings. 1-1. DOI: 10.1038/Npre.2011.5627.1 |
0.415 |
|
2011 |
Mittag T, Orlicky S, Tang X, Sicheri F, Tyers M, Forman-Kay JD. The Role of Dynamic Protein Complexes in the Ubiquitin-Proteasome Pathway Biophysical Journal. 100: 518a-519a. DOI: 10.1016/J.Bpj.2010.12.3032 |
0.357 |
|
2010 |
Liu G, Zhang J, Larsen B, Stark C, Breitkreutz A, Lin ZY, Breitkreutz BJ, Ding Y, Colwill K, Pasculescu A, Pawson T, Wrana JL, Nesvizhskii AI, Raught B, Tyers M, et al. ProHits: integrated software for mass spectrometry-based interaction proteomics. Nature Biotechnology. 28: 1015-7. PMID 20944583 DOI: 10.1038/Nbt1010-1015 |
0.764 |
|
2010 |
Ishizaki H, Spitzer M, Wildenhain J, Anastasaki C, Zeng Z, Dolma S, Shaw M, Madsen E, Gitlin J, Marais R, Tyers M, Patton EE. Combined zebrafish-yeast chemical-genetic screens reveal gene-copper-nutrition interactions that modulate melanocyte pigmentation. Disease Models & Mechanisms. 3: 639-51. PMID 20713646 DOI: 10.1242/Dmm.005769 |
0.651 |
|
2010 |
Orlicky S, Tang X, Neduva V, Elowe N, Brown ED, Sicheri F, Tyers M. An allosteric inhibitor of substrate recognition by the SCF Cdc4 ubiquitin ligase Nature Biotechnology. 28: 733-737. PMID 20581844 DOI: 10.1038/Nbt.1646 |
0.401 |
|
2010 |
Breitkreutz A, Choi H, Sharom JR, Boucher L, Neduva V, Larsen B, Lin ZY, Breitkreutz BJ, Stark C, Liu G, Ahn J, Dewar-Darch D, Reguly T, Tang X, Almeida R, ... Tyers M, et al. A global protein kinase and phosphatase interaction network in yeast. Science (New York, N.Y.). 328: 1043-6. PMID 20489023 DOI: 10.1126/Science.1176495 |
0.8 |
|
2010 |
Stark C, Su TC, Breitkreutz A, Lourenco P, Dahabieh M, Breitkreutz BJ, Tyers M, Sadowski I. PhosphoGRID: a database of experimentally verified in vivo protein phosphorylation sites from the budding yeast Saccharomyces cerevisiae. Database : the Journal of Biological Databases and Curation. 2010: bap026. PMID 20428315 DOI: 10.1093/Database/Bap026 |
0.78 |
|
2010 |
Mittag T, Marsh J, Grishaev A, Orlicky S, Lin H, Sicheri F, Tyers M, Forman-Kay JD. Structure/Function Implications in a Dynamic Complex of the Intrinsically Disordered Sic1 with the Cdc4 Subunit of an SCF Ubiquitin Ligase Structure. 18: 494-506. PMID 20399186 DOI: 10.1016/J.Str.2010.01.020 |
0.382 |
|
2010 |
Lee TA, Jorgensen P, Bognar AL, Peyraud C, Thomas D, Tyers M. Dissection of combinatorial control by the Met4 transcriptional complex. Molecular Biology of the Cell. 21: 456-69. PMID 19940020 DOI: 10.1091/Mbc.E09-05-0420 |
0.348 |
|
2009 |
Salwinski L, Licata L, Winter A, Thorneycroft D, Khadake J, Ceol A, Aryamontri AC, Oughtred R, Livstone M, Boucher L, Botstein D, Dolinski K, Berardini T, Huala E, Tyers M, et al. Recurated protein interaction datasets. Nature Methods. 6: 860-1. PMID 19935838 DOI: 10.1038/Nmeth1209-860 |
0.419 |
|
2009 |
Singh J, Tyers M. A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis. Genes & Development. 23: 1944-58. PMID 19684114 DOI: 10.1101/Gad.1804409 |
0.437 |
|
2009 |
Goranov AI, Cook M, Ricicova M, Ben-Ari G, Gonzalez C, Hansen C, Tyers M, Amon A. The rate of cell growth is governed by cell cycle stage Genes and Development. 23: 1408-1422. PMID 19528319 DOI: 10.1101/Gad.1777309 |
0.303 |
|
2009 |
Olma MH, Roy M, Le Bihan T, Sumara I, Maerki S, Larsen B, Quadroni M, Peter M, Tyers M, Pintard L. An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases. Journal of Cell Science. 122: 1035-44. PMID 19295130 DOI: 10.1242/Jcs.043539 |
0.451 |
|
2009 |
Diamandis P, Sacher AG, Tyers M, Dirks PB. New drugs for brain tumors? Insights from chemical probing of neural stem cells. Medical Hypotheses. 72: 683-7. PMID 19261391 DOI: 10.1016/J.Mehy.2008.10.034 |
0.701 |
|
2008 |
Mittag T, Orlicky S, Choy WY, Tang X, Lin H, Sicheri F, Kay LE, Tyers M, Forman-Kay JD. Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor. Proceedings of the National Academy of Sciences of the United States of America. 105: 17772-7. PMID 19008353 DOI: 10.1073/Pnas.0809222105 |
0.379 |
|
2008 |
Singer AU, Rohde JR, Lam R, Skarina T, Kagan O, Dileo R, Chirgadze NY, Cuff ME, Joachimiak A, Tyers M, Sansonetti PJ, Parsot C, Savchenko A. Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases. Nature Structural & Molecular Biology. 15: 1293-301. PMID 18997778 DOI: 10.1038/Nsmb.1511 |
0.321 |
|
2008 |
Ericson E, Gebbia M, Heisler LE, Wildenhain J, Tyers M, Giaever G, Nislow C. Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast Plos Genetics. 4. PMID 18688276 DOI: 10.1371/Journal.Pgen.1000151 |
0.311 |
|
2008 |
Rajakulendran T, Sahmi M, Kurinov I, Tyers M, Therrien M, Sicheri F. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 2836-41. PMID 18287031 DOI: 10.1073/Pnas.0709705105 |
0.37 |
|
2008 |
Kurz T, Chou YC, Willems AR, Meyer-Schaller N, Hecht ML, Tyers M, Peter M, Sicheri F. Dcn1 Functions as a Scaffold-Type E3 Ligase for Cullin Neddylation Molecular Cell. 29: 23-35. PMID 18206966 DOI: 10.1016/J.Molcel.2007.12.012 |
0.743 |
|
2008 |
Breitkreutz BJ, Stark C, Reguly T, Boucher L, Breitkreutz A, Livstone M, Oughtred R, Lackner DH, Bähler J, Wood V, Dolinski K, Tyers M. The BioGRID Interaction Database: 2008 update. Nucleic Acids Research. 36: D637-40. PMID 18000002 DOI: 10.1093/Nar/Gkm1001 |
0.783 |
|
2007 |
Kerrien S, Orchard S, Montecchi-Palazzi L, Aranda B, Quinn AF, Vinod N, Bader GD, Xenarios I, Wojcik J, Sherman D, Tyers M, Salama JJ, Moore S, Ceol A, Chatr-Aryamontri A, et al. Broadening the horizon--level 2.5 of the HUPO-PSI format for molecular interactions. Bmc Biology. 5: 44. PMID 17925023 DOI: 10.1186/1741-7007-5-44 |
0.388 |
|
2007 |
Betel D, Breitkreuz KE, Isserlin R, Dewar-Darch D, Tyers M, Hogue CW. Structure-templated predictions of novel protein interactions from sequence information. Plos Computational Biology. 3: 1783-9. PMID 17892321 DOI: 10.1371/Journal.Pcbi.0030182 |
0.416 |
|
2007 |
Luke-Glaser S, Pintard L, Tyers M, Peter M. The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line. Journal of Cell Science. 120: 3179-87. PMID 17878235 DOI: 10.1242/Jcs.015883 |
0.382 |
|
2007 |
Orchard S, Salwinski L, Kerrien S, Montecchi-Palazzi L, Oesterheld M, Stümpflen V, Ceol A, Chatr-aryamontri A, Armstrong J, Woollard P, Salama JJ, Moore S, Wojcik J, Bader GD, Vidal M, ... Tyers M, et al. The minimum information required for reporting a molecular interaction experiment (MIMIx). Nature Biotechnology. 25: 894-8. PMID 17687370 DOI: 10.1038/Nbt1324 |
0.342 |
|
2007 |
Jorgensen P, Edgington NP, Schneider BL, Rupes I, Tyers M, Futcher B. The size of the nucleus increases as yeast cells grow. Molecular Biology of the Cell. 18: 3523-32. PMID 17596521 DOI: 10.1091/Mbc.E06-10-0973 |
0.624 |
|
2007 |
Tang X, Orlicky S, Lin Z, Willems A, Neculai D, Ceccarelli D, Mercurio F, Shilton BH, Sicheri F, Tyers M. Suprafacial Orientation of the SCFCdc4 Dimer Accommodates Multiple Geometries for Substrate Ubiquitination Cell. 129: 1165-1176. PMID 17574027 DOI: 10.1016/J.Cell.2007.04.042 |
0.747 |
|
2007 |
Batada NN, Reguly T, Breitkreutz A, Boucher L, Breitkreutz BJ, Hurst LD, Tyers M. Still stratus not altocumulus: further evidence against the date/party hub distinction. Plos Biology. 5: e154. PMID 17564494 DOI: 10.1371/Journal.Pbio.0050154 |
0.763 |
|
2007 |
Borg M, Mittag T, Pawson T, Tyers M, Forman-Kay JD, Chan HS. Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity. Proceedings of the National Academy of Sciences of the United States of America. 104: 9650-5. PMID 17522259 DOI: 10.1073/Pnas.0702580104 |
0.412 |
|
2007 |
Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB. Chemical genetics reveals a complex functional ground state of neural stem cells. Nature Chemical Biology. 3: 268-73. PMID 17417631 DOI: 10.25011/Cim.V31I4.4797 |
0.716 |
|
2007 |
Luke-Glaser S, Roy M, Larsen B, Le Bihan T, Metalnikov P, Tyers M, Peter M, Pintard L. CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo. Molecular and Cellular Biology. 27: 4526-40. PMID 17403899 DOI: 10.1128/Mcb.01724-06 |
0.445 |
|
2006 |
Woolstencroft RN, Beilharz TH, Cook MA, Preiss T, Durocher D, Tyers M. Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length. Journal of Cell Science. 119: 5178-92. PMID 17158920 DOI: 10.1242/Jcs.03221 |
0.314 |
|
2006 |
Batada NN, Reguly T, Breitkreutz A, Boucher L, Breitkreutz BJ, Hurst LD, Tyers M. Stratus not altocumulus: a new view of the yeast protein interaction network. Plos Biology. 4: e317. PMID 16984220 DOI: 10.1371/Journal.Pbio.0040317 |
0.794 |
|
2006 |
Mrkobrada S, Boucher L, Ceccarelli DF, Tyers M, Sicheri F. Structural and functional analysis of Saccharomyces cerevisiae Mob1. Journal of Molecular Biology. 362: 430-40. PMID 16934835 DOI: 10.1016/J.Jmb.2006.07.007 |
0.33 |
|
2006 |
Batada NN, Hurst LD, Tyers M. Evolutionary and physiological importance of hub proteins. Plos Computational Biology. 2: e88. PMID 16839197 DOI: 10.1371/Journal.Pcbi.0020088 |
0.438 |
|
2006 |
Reguly T, Breitkreutz A, Boucher L, Breitkreutz BJ, Hon GC, Myers CL, Parsons A, Friesen H, Oughtred R, Tong A, Stark C, Ho Y, Botstein D, Andrews B, Boone C, ... Tyers M, et al. Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae. Journal of Biology. 5: 11. PMID 16762047 DOI: 10.1186/Jbiol36 |
0.806 |
|
2006 |
Blake D, Luke B, Kanellis P, Jorgensen P, Goh T, Penfold S, Breitkreutz BJ, Durocher D, Peter M, Tyers M. The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharomyces cerevisiae. Genetics. 174: 1709-27. PMID 16751663 DOI: 10.1534/Genetics.106.057836 |
0.375 |
|
2006 |
Menant A, Baudouin-Cornu P, Peyraud C, Tyers M, Thomas D. Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor. The Journal of Biological Chemistry. 281: 11744-54. PMID 16497670 DOI: 10.1074/Jbc.M600037200 |
0.361 |
|
2006 |
Breitkreutz A, Tyers M. Cell signaling. A sophisticated scaffold wields a new trick. Science (New York, N.Y.). 311: 789-90. PMID 16469909 DOI: 10.1126/Science.1124620 |
0.772 |
|
2006 |
Stark C, Breitkreutz BJ, Reguly T, Boucher L, Breitkreutz A, Tyers M. BioGRID: a general repository for interaction datasets. Nucleic Acids Research. 34: D535-9. PMID 16381927 DOI: 10.1093/Nar/Gkj109 |
0.784 |
|
2005 |
Tang X, Orlicky S, Liu Q, Willems A, Sicheri F, Tyers M. Genome-wide surveys for phosphorylation-dependent substrates of SCF ubiquitin ligases Methods in Enzymology. 399: 433-458. PMID 16338374 DOI: 10.1016/S0076-6879(05)99030-7 |
0.776 |
|
2005 |
Ptacek J, Devgan G, Michaud G, Zhu H, Zhu X, Fasolo J, Guo H, Jona G, Breitkreutz A, Sopko R, McCartney RR, Schmidt MC, Rachidi N, Lee SJ, Mah AS, ... Tyers M, et al. Global analysis of protein phosphorylation in yeast. Nature. 438: 679-84. PMID 16319894 DOI: 10.1038/Nature04187 |
0.81 |
|
2005 |
Cho HP, Liu Y, Gomez M, Dunlap J, Tyers M, Wang Y. The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules. Molecular and Cellular Biology. 25: 4541-51. PMID 15899858 DOI: 10.1128/Mcb.25.11.4541-4551.2005 |
0.344 |
|
2005 |
Barbey R, Baudouin-Cornu P, Lee TA, Rouillon A, Zarzov P, Tyers M, Thomas D. Inducible dissociation of SCF(Met30) ubiquitin ligase mediates a rapid transcriptional response to cadmium. The Embo Journal. 24: 521-32. PMID 15660125 DOI: 10.1038/Sj.Emboj.7600556 |
0.337 |
|
2004 |
Jorgensen P, Tyers M. How cells coordinate growth and division. Current Biology : Cb. 14: R1014-27. PMID 15589139 DOI: 10.1016/J.Cub.2004.11.027 |
0.323 |
|
2004 |
Sarin S, Ross KE, Boucher L, Green Y, Tyers M, Cohen-Fix O. Uncovering novel cell cycle players through the inactivation of securin in budding yeast. Genetics. 168: 1763-71. PMID 15579722 DOI: 10.1534/Genetics.104.029033 |
0.369 |
|
2004 |
Willems AR, Schwab M, Tyers M. A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin. Biochimica Et Biophysica Acta. 1695: 133-70. PMID 15571813 DOI: 10.1016/J.Bbamcr.2004.09.027 |
0.78 |
|
2004 |
Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, ... Tyers M, et al. Varshavsky's contributions. Science (New York, N.Y.). 306: 1290-2. PMID 15550643 DOI: 10.1126/Science.306.5700.1290 |
0.347 |
|
2004 |
Tyers M. Cell cycle goes global. Current Opinion in Cell Biology. 16: 602-13. PMID 15530770 DOI: 10.1016/J.Ceb.2004.09.013 |
0.38 |
|
2004 |
Jorgensen P, Rupes I, Sharom JR, Schneper L, Broach JR, Tyers M. A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size. Genes & Development. 18: 2491-505. PMID 15466158 DOI: 10.1101/Gad.1228804 |
0.363 |
|
2004 |
Bellows DS, Tyers M. Cell biology. Chemical genetics hits. Science (New York, N.Y.). 306: 67-8. PMID 15459377 DOI: 10.1126/Science.1104611 |
0.319 |
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2004 |
Costanzo M, Nishikawa JL, Tang X, Millman JS, Schub O, Breitkreuz K, Dewar D, Rupes I, Andrews B, Tyers M. CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell. 117: 899-913. PMID 15210111 DOI: 10.1016/J.Cell.2004.05.024 |
0.578 |
|
2004 |
Sharom JR, Bellows DS, Tyers M. From large networks to small molecules. Current Opinion in Chemical Biology. 8: 81-90. PMID 15036161 DOI: 10.1016/J.Cbpa.2003.12.007 |
0.323 |
|
2004 |
Cook MA, Tyers M. Cellular differentiation: the violin strikes up another tune. Current Biology : Cb. 14: R11-3. PMID 14711426 DOI: 10.1016/J.Cub.2003.12.013 |
0.316 |
|
2004 |
Klein P, Pawson T, Tyers M. Mathematical modeling suggests cooperative interactions between a disordered polyvalent ligand and a single receptor site. Current Biology : Cb. 13: 1669-78. PMID 14521832 DOI: 10.1016/J.Cub.2003.09.027 |
0.329 |
|
2004 |
Jorgensen P, Tyers M, Warner JR. 11 Forging the Factory: Ribosome Synthesis and Growth Control in Budding Yeast Cold Spring Harbor Monograph Archive. 42: 329-370. DOI: 10.1101/087969672.42.329 |
0.333 |
|
2004 |
Bellows D, Jorgensen P, Tyers M, Bellows D. 102 The synthetic lethal trap: a general approach for screening small-molecule protein inhibitors using genetic triangulation in the yeast Saccharomyces cerevisiae European Journal of Cancer Supplements. 2: 33-34. DOI: 10.1016/S1359-6349(04)80110-1 |
0.334 |
|
2003 |
Jorgensen P, Breitkreutz BJ, Breitkreutz K, Stark C, Liu G, Cook M, Sharom J, Nishikawa JL, Ketela T, Bellows D, Breitkreutz A, Rupes I, Boucher L, Dewar D, Vo M, ... ... Tyers M, et al. Harvesting the genome's bounty: integrative genomics. Cold Spring Harbor Symposia On Quantitative Biology. 68: 431-43. PMID 15338646 DOI: 10.1101/Sqb.2003.68.431 |
0.496 |
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2003 |
Breitkreutz A, Boucher L, Breitkreutz BJ, Sultan M, Jurisica I, Tyers M. Phenotypic and transcriptional plasticity directed by a yeast mitogen-activated protein kinase network. Genetics. 165: 997-1015. PMID 14668360 |
0.748 |
|
2003 |
Pintard L, Willis JH, Willems A, Johnson JL, Srayko M, Kurz T, Glaser S, Mains PE, Tyers M, Bowerman B, Peter M. The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. Nature. 425: 311-6. PMID 13679921 DOI: 10.1038/Nature01959 |
0.782 |
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2003 |
Friesen H, Murphy K, Breitkreutz A, Tyers M, Andrews B. Regulation of the yeast amphiphysin homologue Rvs167p by phosphorylation. Molecular Biology of the Cell. 14: 3027-40. PMID 12857883 DOI: 10.1091/Mbc.E02-09-0613 |
0.799 |
|
2003 |
Bader GD, Heilbut A, Andrews B, Tyers M, Hughes T, Boone C. Functional genomics and proteomics: charting a multidimensional map of the yeast cell. Trends in Cell Biology. 13: 344-56. PMID 12837605 DOI: 10.1016/S0962-8924(03)00127-2 |
0.573 |
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2003 |
Tyers M, Mann M. From genomics to proteomics. Nature. 422: 193-7. PMID 12634792 DOI: 10.1038/Nature01510 |
0.396 |
|
2003 |
Breitkreutz BJ, Stark C, Tyers M. The GRID: the General Repository for Interaction Datasets. Genome Biology. 4: R23. PMID 12620108 DOI: 10.1186/Gb-2003-4-3-R23 |
0.382 |
|
2003 |
Breitkreutz BJ, Stark C, Tyers M. Osprey: a network visualization system. Genome Biology. 4: R22. PMID 12620107 DOI: 10.1186/Gb-2003-4-3-R22 |
0.341 |
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2003 |
Orlicky S, Tang X, Willems A, Tyers M, Sicheri F. Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase Cell. 112: 243-256. PMID 12553912 DOI: 10.1016/S0092-8674(03)00034-5 |
0.747 |
|
2002 |
Jorgensen P, Nelson B, Robinson MD, Chen Y, Andrews B, Tyers M, Boone C. High-resolution genetic mapping with ordered arrays of Saccharomyces cerevisiae deletion mutants. Genetics. 162: 1091-9. PMID 12454058 |
0.5 |
|
2002 |
Kuras L, Rouillon A, Lee T, Barbey R, Tyers M, Thomas D. Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment. Molecular Cell. 10: 69-80. PMID 12150908 DOI: 10.1016/S1097-2765(02)00561-0 |
0.329 |
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2002 |
Jorgensen P, Nishikawa JL, Breitkreutz BJ, Tyers M. Systematic identification of pathways that couple cell growth and division in yeast. Science (New York, N.Y.). 297: 395-400. PMID 12089449 DOI: 10.1126/Science.1070850 |
0.352 |
|
2002 |
Breitkreutz A, Tyers M. MAPK signaling specificity: it takes two to tango. Trends in Cell Biology. 12: 254-7. PMID 12074884 DOI: 10.1016/S0962-8924(02)02284-5 |
0.761 |
|
2002 |
Ho Y, Gruhler A, Heilbut A, Bader GD, Moore L, Adams SL, Millar A, Taylor P, Bennett K, Boutilier K, Yang L, Wolting C, Donaldson I, Schandorff S, Shewnarane J, ... Tyers M, et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 415: 180-3. PMID 11805837 DOI: 10.1038/415180A |
0.782 |
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2001 |
Tong AH, Evangelista M, Parsons AB, Xu H, Bader GD, Pagé N, Robinson M, Raghibizadeh S, Hogue CW, Bussey H, Andrews B, Tyers M, Boone C. Systematic genetic analysis with ordered arrays of yeast deletion mutants. Science (New York, N.Y.). 294: 2364-8. PMID 11743205 DOI: 10.1126/Science.1065810 |
0.562 |
|
2001 |
Nash P, Tang X, Orlicky S, Chen Q, Gertler FB, Mendenhall MD, Sicheri F, Pawson T, Tyers M. Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication. Nature. 414: 514-21. PMID 11734846 DOI: 10.1038/35107009 |
0.429 |
|
2001 |
Lee TA, Tyers M. Ubiquitin junction, what's your function? Genome Biology. 2. PMID 11597332 DOI: 10.1186/Gb-2001-2-10-Reports4025 |
0.36 |
|
2001 |
Ashman K, Moran MF, Sicheri F, Pawson T, Tyers M. Cell signalling - the proteomics of it all. Science's Stke : Signal Transduction Knowledge Environment. 2001: PE33. PMID 11593049 DOI: 10.1126/Stke.2001.103.Pe33 |
0.383 |
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2001 |
Schwab M, Tyers M. Cell cycle. Archipelago of destruction. Nature. 413: 268-9. PMID 11565017 DOI: 10.1038/35095157 |
0.311 |
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2001 |
Breitkreutz A, Boucher L, Tyers M. MAPK specificity in the yeast pheromone response independent of transcriptional activation. Current Biology : Cb. 11: 1266-71. PMID 11525741 DOI: 10.1016/S0960-9822(01)00370-0 |
0.407 |
|
2001 |
Trautmann S, Wolfe BA, Jorgensen P, Tyers M, Gould KL, McCollum D. Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression. Current Biology : Cb. 11: 931-40. PMID 11448769 DOI: 10.1016/S0960-9822(01)00268-8 |
0.409 |
|
2001 |
Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, Pagano M, Hershko A. The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nature Cell Biology. 3: 321-4. PMID 11231585 DOI: 10.1038/35060126 |
0.428 |
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2001 |
Alexander MR, Tyers M, Perret M, Craig BM, Fang KS, Gustin MC. Regulation of cell cycle progression by Swe1p and Hog1p following hypertonic stress. Molecular Biology of the Cell. 12: 53-62. PMID 11160822 DOI: 10.1091/Mbc.12.1.53 |
0.347 |
|
2000 |
Patton EE, Peyraud C, Rouillon A, Surdin-Kerjan Y, Tyers M, Thomas D. SCF(Met30)-mediated control of the transcriptional activator Met4 is required for the G(1)-S transition. The Embo Journal. 19: 1613-24. PMID 10747029 DOI: 10.1093/Emboj/19.7.1613 |
0.672 |
|
2000 |
Tyers M, Jorgensen P. Proteolysis and the cell cycle: with this RING I do thee destroy. Current Opinion in Genetics & Development. 10: 54-64. PMID 10679394 DOI: 10.1016/S0959-437X(99)00049-0 |
0.431 |
|
2000 |
Roberts CJ, Nelson B, Marton MJ, Stoughton R, Meyer MR, Bennett HA, He YD, Dai H, Walker WL, Hughes TR, Tyers M, Boone C, Friend SH. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles Science. 287: 873-880. PMID 10657304 DOI: 10.1126/Science.287.5454.873 |
0.358 |
|
2000 |
Rouillon A, Barbey R, Patton EE, Tyers M, Thomas D. Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex. The Embo Journal. 19: 282-94. PMID 10637232 DOI: 10.1093/Emboj/19.2.282 |
0.706 |
|
2000 |
Jorgensen P, Tyers M. Altered states: programmed proteolysis and the budding yeast cell cycle. Current Opinion in Microbiology. 2: 610-7. PMID 10607629 DOI: 10.1016/S1369-5274(99)00030-2 |
0.408 |
|
1999 |
Willems AR, Goh T, Taylor L, Chernushevich I, Shevchenko A, Tyers M. SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 1533-50. PMID 10582239 DOI: 10.1098/rstb.1999.0497 |
0.77 |
|
1999 |
Craig KL, Tyers M. The F-box: a new motif for ubiquitin dependent proteolysis in cell cycle regulation and signal transduction. Progress in Biophysics and Molecular Biology. 72: 299-328. PMID 10581972 DOI: 10.1016/S0079-6107(99)00010-3 |
0.472 |
|
1999 |
Tyers M, Rottapel R. VHL: A very hip ligase Proceedings of the National Academy of Sciences of the United States of America. 96: 12230-12232. PMID 10535903 DOI: 10.1073/Pnas.96.22.12230 |
0.383 |
|
1999 |
Wang Y, Penfold S, Tang X, Hattori N, Riley P, Harper JW, Cross JC, Tyers M. Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E. Current Biology : Cb. 9: 1191-4. PMID 10531039 DOI: 10.1016/S0960-9822(00)80024-X |
0.42 |
|
1999 |
Tyers M, Willems AR. One ring to rule a superfamily of E3 ubiquitin ligases. Science (New York, N.Y.). 284: 601, 603-4. PMID 10328744 DOI: 10.1126/Science.284.5414.601 |
0.758 |
|
1998 |
Visintin R, Craig K, Hwang ES, Prinz S, Tyers M, Amon A. The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk-dependent phosphorylation Molecular Cell. 2: 709-718. PMID 9885559 DOI: 10.1016/S1097-2765(00)80286-5 |
0.361 |
|
1998 |
Schneider BL, Patton EE, Lanker S, Mendenhall MD, Wittenberg C, Futcher B, Tyers M. Yeast G1 cyclins are unstable in G1 phase. Nature. 395: 86-9. PMID 9738503 DOI: 10.1038/25774 |
0.758 |
|
1998 |
Patton EE, Willems AR, Tyers M. Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis. Trends in Genetics : Tig. 14: 236-43. PMID 9635407 DOI: 10.1016/S0168-9525(98)01473-5 |
0.81 |
|
1998 |
Patton EE, Willems AR, Sa D, Kuras L, Thomas D, Craig KL, Tyers M. Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast. Genes & Development. 12: 692-705. PMID 9499404 DOI: 10.1101/Gad.12.5.692 |
0.81 |
|
1997 |
Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell. 91: 209-19. PMID 9346238 DOI: 10.1016/S0092-8674(00)80403-1 |
0.453 |
|
1997 |
Okano K, Heng H, Trevisanato S, Tyers M, Varmuza S. Genomic organization and functional analysis of the murine protein phosphatase 1c gamma (Ppp1cc) gene. Genomics. 45: 211-5. PMID 9339378 DOI: 10.1006/Geno.1997.4907 |
0.336 |
|
1997 |
Radcliffe P, Trevethick J, Tyers M, Sudbery P. Deregulation of CLN1 and CLN2 in the Saccharomyces cerevisiae whi2 mutant. Yeast (Chichester, England). 13: 707-15. PMID 9219335 DOI: 10.1002/(Sici)1097-0061(19970630)13:8<707::Aid-Yea130>3.0.Co;2-9 |
0.313 |
|
1997 |
Tedford K, Kim S, Sa D, Stevens K, Tyers M. Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Current Biology : Cb. 7: 228-38. PMID 9094309 DOI: 10.1016/S0960-9822(06)00118-7 |
0.351 |
|
1996 |
Willems AR, Lanker S, Patton EE, Craig KL, Nason TF, Mathias N, Kobayashi R, Wittenberg C, Tyers M. Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway. Cell. 86: 453-63. PMID 8756727 DOI: 10.1016/S0092-8674(00)80118-X |
0.814 |
|
1996 |
Tyers M. The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start Proceedings of the National Academy of Sciences of the United States of America. 93: 7772-7776. PMID 8755551 DOI: 10.1073/Pnas.93.15.7772 |
0.392 |
|
1996 |
Siderovski DP, Hessel A, Chung S, Mak TW, Tyers M. A new family of regulators of G-protein-coupled receptors? Current Biology : Cb. 6: 211-2. PMID 8673468 DOI: 10.1016/S0960-9822(02)00454-2 |
0.329 |
|
1994 |
Tokiwa G, Tyers M, Volpe T, Futcher B. Inhibition of G1 cyclin activity by the Ras/cAMP pathway in yeast. Nature. 371: 342-5. PMID 8090204 DOI: 10.1038/371342a0 |
0.629 |
|
1994 |
Measday V, Moore L, Ogas J, Tyers M, Andrews B. The PCL2 (ORFD)-PHOSS cyclin-dependent kinase complex: A cell cycle regulator in yeast Science. 266: 1391-1395. PMID 7973731 DOI: 10.1126/Science.7973731 |
0.612 |
|
1993 |
Linskens M, Tyers M, Futcher B. CLN3 functions in both daughter and mother cells of S. cerevisiae. Cell. 72: 487-8. PMID 8440016 DOI: 10.1016/0092-8674(93)90067-Z |
0.601 |
|
1993 |
Amon A, Tyers M, Futcher B, Nasmyth K. Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins. Cell. 74: 993-1007. PMID 8402888 DOI: 10.1016/0092-8674(93)90722-3 |
0.611 |
|
1993 |
Tyers M, Futcher B. Far1 and Fus3 link the mating pheromone signal transduction pathway to three G1-phase Cdc28 kinase complexes. Molecular and Cellular Biology. 13: 5659-69. PMID 8395009 DOI: 10.1128/Mcb.13.9.5659 |
0.691 |
|
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