George T. Bowden - Publications

Affiliations: 
University of Arizona, Tucson, AZ 
Area:
Oncology, Molecular Biology

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Bermudez Y, Stratton SP, Curiel-Lewandrowski C, Warneke J, Hu C, Bowden GT, Dickinson SE, Dong Z, Bode AM, Saboda K, Brooks CA, Petricoin EF, Hurst CA, Alberts DS, Einspahr JG. Activation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin. Cancer Prevention Research (Philadelphia, Pa.). 8: 720-8. PMID 26031292 DOI: 10.1158/1940-6207.Capr-14-0407  0.38
2014 Stratton SP, Curiel-Lewandrowski C, Einspahr JG, Calvert V, Hu C, Bermudez Y, Alberts DS, Bowden GT, Petricoin EF. Abstract 3246: Mapping of functional protein pathway modulations in non-sun exposed skin of healthy volunteers using solar simulated light: A new model for pharmacodynamic testing of skin cancer chemopreventive drugs Cancer Research. 74: 3246-3246. DOI: 10.1158/1538-7445.Am2014-3246  0.355
2013 Bermudez Y, Stratton SP, Curiel-Lewandrowski C, Hu C, Bowden GT, Saboda K, Alberts DS, Einspahr JG. Abstract 4264: PI3K/Akt/mTOR signaling modulation in solar UV-induced skin carcinogenesis. Cancer Research. 73: 4264-4264. DOI: 10.1158/1538-7445.Am2013-4264  0.425
2011 Zhang J, Bowden GT. Activation of p38 MAP kinase and JNK pathways by UVA irradiation. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 11: 54-61. PMID 21858326 DOI: 10.1039/c1pp05133d  0.309
2011 Lee DE, Lee KW, Byun S, Jung SK, Song N, Lim SH, Heo YS, Kim JE, Kang NJ, Kim BY, Bowden GT, Bode AM, Lee HJ, Dong Z. 7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4. The Journal of Biological Chemistry. 286: 14246-56. PMID 21378167 DOI: 10.1074/jbc.M110.147348  0.311
2011 Dickinson SE, Olson ER, Zhang J, Cooper SJ, Melton T, Criswell PJ, Casanova A, Dong Z, Hu C, Saboda K, Jacobs ET, Alberts DS, Bowden GT. p38 MAP kinase plays a functional role in UVB-induced mouse skin carcinogenesis. Molecular Carcinogenesis. 50: 469-78. PMID 21268131 DOI: 10.1002/Mc.20734  0.317
2011 Bermudez Y, Stratton SP, Bowden GT, Dong Z, Bode AM, Curiel-Lewandrowski C, Warneke JA, Hurst CA, Lang JE, Alberts DS, Einspahr JG. Abstract 3673: Expression profile of phosphorylated proteins from the mTOR and Fyn/RSK2 signaling pathways in solar UV-induced skin carcinogenesis Cancer Research. 71: 3673-3673. DOI: 10.1158/1538-7445.Am2011-3673  0.402
2008 Demetriou MC, Kwei KA, Powell MB, Nagle RB, Bowden GT, Cress AE. Integrin A6 Cleavage in Mouse Skin Tumors. The Open Cancer Journal. 2: 1-4. PMID 20664806 DOI: 10.2174/1874079000802010001  0.71
2008 Jung SK, Lee KW, Byun S, Kang NJ, Lim SH, Heo YS, Bode AM, Bowden GT, Lee HJ, Dong Z. Myricetin suppresses UVB-induced skin cancer by targeting Fyn. Cancer Research. 68: 6021-9. PMID 18632659 DOI: 10.1158/0008-5472.CAN-08-0899  0.313
2008 Sroka IC, McDaniel K, Nagle RB, Bowden GT. Differential localization of MT1-MMP in human prostate cancer tissue: role of IGF-1R in MT1-MMP expression. The Prostate. 68: 463-76. PMID 18196535 DOI: 10.1002/Pros.20718  0.696
2007 Gu Q, Bowden GT, Normolle D, Sun Y. SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IkappaB-alpha/NF-kappaB. The Journal of Cell Biology. 178: 1009-23. PMID 17846172 DOI: 10.1083/jcb.200612067  0.301
2007 Sroka IC, Nagle RB, Bowden GT. Membrane-type 1 matrix metalloproteinase is regulated by sp1 through the differential activation of AKT, JNK, and ERK pathways in human prostate tumor cells. Neoplasia (New York, N.Y.). 9: 406-17. PMID 17534446 DOI: 10.1593/Neo.07193  0.724
2006 Finch JS, Tome ME, Kwei KA, Bowden GT. Catalase reverses tumorigenicity in a malignant cell line by an epidermal growth factor receptor pathway. Free Radical Biology & Medicine. 40: 863-75. PMID 16520238 DOI: 10.1016/J.Freeradbiomed.2005.10.036  0.718
2006 Zhu M, Zhang Y, Bowden GT. Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes. Cancer Letters. 244: 220-8. PMID 16455194 DOI: 10.1016/J.CANLET.2005.12.023  0.343
2006 Kwei KA, Finch JS, Ranger-Moore J, Bowden GT. The role of Rac1 in maintaining malignant phenotype of mouse skin tumor cells. Cancer Letters. 231: 326-38. PMID 15893875 DOI: 10.1016/J.Canlet.2005.02.031  0.735
2005 Bair EL, Chen ML, McDaniel K, Sekiguchi K, Cress AE, Nagle RB, Bowden GT. Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration. Neoplasia (New York, N.Y.). 7: 380-9. PMID 15967115 DOI: 10.1593/Neo.04619  0.403
2005 Zubriski MA, Bair EL, Calaluce R, Bowden GT, Nagle RB. 229 DETECTION OF PROSTATE CANCER METASTASIS USING IN SITU HYBRIDIZATION FOR MEMBRANE-TYPE-1 MATRIX METALLOPROTEASE Journal of Investigative Medicine. 53: S118.2-S118. DOI: 10.2310/6650.2005.00005.228  0.396
2004 Kwei KA, Finch JS, Thompson EJ, Bowden GT. Transcriptional repression of catalase in mouse skin tumor progression. Neoplasia (New York, N.Y.). 6: 440-8. PMID 15548352 DOI: 10.1593/Neo.04127  0.725
2004 Bachelor MA, Bowden GT. UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression. Seminars in Cancer Biology. 14: 131-8. PMID 15018897 DOI: 10.1016/J.SEMCANCER.2003.09.017  0.358
2004 Udayakumar TS, Nagle RB, Bowden GT. Fibroblast growth factor-1 transcriptionally induces membrane type-1 matrix metalloproteinase expression in prostate carcinoma cell line. The Prostate. 58: 66-75. PMID 14673954 DOI: 10.1002/PROS.10293  0.315
2004 Horn EJ, Albor A, Liu Y, El-Hizawi S, Vanderbeek GE, Babcock M, Bowden GT, Hennings H, Lozano G, Weinberg WC, Kulesz-Martin M. RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties Carcinogenesis. 25: 157-167. PMID 14578165 DOI: 10.1093/Carcin/Bgh003  0.333
2003 Dilley TK, Bowden GT, Chen QM. Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity. Experimental Cell Research. 290: 38-48. PMID 14516786 DOI: 10.1016/S0014-4827(03)00308-2  0.343
2003 Butts BD, Kwei KA, Bowden GT, Briehl MM. Elevated basal reactive oxygen species and phospho-Akt in murine keratinocytes resistant to ultraviolet B-induced apoptosis. Molecular Carcinogenesis. 37: 149-57. PMID 12884366 DOI: 10.1002/Mc.10131  0.692
2002 Gonzales M, Bowden GT. Nordihydroguaiaretic acid-mediated inhibition of ultraviolet B-induced activator protein-1 activation in human keratinocytes Molecular Carcinogenesis. 34: 102-111. PMID 12112316 DOI: 10.1002/mc.10052  0.315
2002 Udayakumar TS, Stratton MS, Nagle RB, Bowden GT. Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3. Neoplasia (New York, N.Y.). 4: 60-7. PMID 11922392 DOI: 10.1038/Sj.Neo.7900207  0.46
2002 Finch JS, Joseloff E, Bowden GT. JunB negatively regulates AP-1 activity and cell proliferation of malignant mouse keratinocytes. Journal of Cancer Research and Clinical Oncology. 128: 3-10. PMID 11862466 DOI: 10.1007/S00432-001-0298-X  0.501
2001 Bair EL, Massey CP, Tran NL, Borchers AH, Heimark RL, Cress AE, Bowden GT. Integrin- and cadherin-mediated induction of the matrix metalloprotease matrilysin in cocultures of malignant oral squamous cell carcinoma cells and dermal fibroblasts. Experimental Cell Research. 270: 259-67. PMID 11640889 DOI: 10.1006/Excr.2001.5347  0.414
2001 Gupta A, Butts B, Kwei KA, Dvorakova K, Stratton SP, Briehl MM, Bowden GT. Attenuation of catalase activity in the malignant phenotype plays a functional role in an in vitro model for tumor progression. Cancer Letters. 173: 115-25. PMID 11597785 DOI: 10.1016/S0304-3835(01)00656-5  0.697
2001 Stratton MS, Sirvent H, Udayakumar TS, Nagle RB, Bowden GT. Expression of the matrix metalloproteinase promatrilysin in coculture of prostate carcinoma cell lines. The Prostate. 48: 206-9. PMID 11494336 DOI: 10.1002/Pros.1099  0.443
2001 Finch JS, Rosenberger SF, Martinez JD, Bowden GT. Okadaic acid induces transcription of junB through a CCAAT box and NF-Y. Gene. 267: 135-44. PMID 11311563 DOI: 10.1016/S0378-1119(01)00398-5  0.362
2001 Udayakumar TS, Klein RD, Maliner MS, Nagle RB, Bowden GT. Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors: FGFR-1 Expression in Prostate Epithelial Cells International Journal of Cancer. 91: 187-192. DOI: 10.1002/1097-0215(200002)9999:9999<::Aid-Ijc1023>3.0.Co;2-W  0.392
2000 Nomura M, Ma WY, Huang C, Yang CS, Bowden GT, Miyamoto K, Dong Z. Inhibition of ultraviolet B-induced AP-1 activation by theaflavins from black tea. Molecular Carcinogenesis. 28: 148-55. PMID 10942531 DOI: 10.1002/1098-2744(200007)28:3<148::Aid-Mc3>3.0.Co;2-Q  0.308
2000 Witkowski CM, Bowden GT, Nagle RB, Cress AE. Altered surface expression and increased turnover of the alpha6beta4 integrin in an undifferentiated carcinoma. Carcinogenesis. 21: 325-30. PMID 10657977 DOI: 10.1093/Carcin/21.2.325  0.329
2000 Chen W, Bowden GT. Activation of p38 MAP kinase and ERK are required for ultraviolet-B induced c-fos gene expression in human keratinocytes. Oncogene. 18: 7469-76. PMID 10602506 DOI: 10.1038/Sj.Onc.1203210  0.389
2000 Gupta A, Rosenberger SF, Bowden GT. Increased ROS levels contribute to elevated transcription factor and MAP kinase activities in malignantly progressed mouse keratinocyte cell lines. Carcinogenesis. 20: 2063-73. PMID 10545407 DOI: 10.1093/CARCIN/20.11.2063  0.387
2000 Udayakumar T, Klein RD, Maliner MS, Nagle RB, Bowden G. Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors International Journal of Cancer. 91: 187-192. DOI: 10.1002/1097-0215(200002)9999:9999<::Aid-Ijc1023>3.3.Co;2-N  0.446
1999 Klein RD, Maliner-Jongewaard MS, Udayakumar TS, Boyd JL, Nagle RB, Bowden GT. Promatrilysin expression is induced by fibroblast growth factors in the prostatic carcinoma cell line LNCaP but not in normal primary prostate epithelial cells. The Prostate. 41: 215-23. PMID 10544294 DOI: 10.1002/(SICI)1097-0045(19991201)41:4<215::AID-PROS1>3.0.CO;2-V  0.312
1999 Sundareshan P, Nagle RB, Bowden GT. EGF induces the expression of matrilysin in the human prostate adenocarcinoma cell line, LNCaP. The Prostate. 40: 159-66. PMID 10398277 DOI: 10.1002/(SICI)1097-0045(19990801)40:3<159::AID-PROS3>3.0.CO;2-W  0.369
1999 Gupta A, Andrews KL, McDaniel KM, Nagle RB, Bowden GT. Experimental induction of rhabdomyosarcoma in mice with fractionated doses of beta-irradiation. Journal of Cancer Research and Clinical Oncology. 125: 257-67. PMID 10359130 DOI: 10.1007/s004320050272  0.303
1999 Chen W, Dong Z, Valcic S, Timmermann BN, Bowden GT. Inhibition of ultraviolet B--induced c-fos gene expression and p38 mitogen-activated protein kinase activation by (-)-epigallocatechin gallate in a human keratinocyte cell line. Molecular Carcinogenesis. 24: 79-84. PMID 10078934 DOI: 10.1002/(Sici)1098-2744(199902)24:2<79::Aid-Mc1>3.0.Co;2-E  0.305
1999 Rosenberger SF, Finch JS, Gupta A, Bowden GT. Extracellular signal-regulated kinase 1/2-mediated phosphorylation of JunD and FosB is required for okadaic acid-induced activator protein 1 activation. The Journal of Biological Chemistry. 274: 1124-30. PMID 9873060 DOI: 10.1074/Jbc.274.2.1124  0.383
1998 Barthelman M, Bair WB, Stickland KK, Chen W, Timmermann BN, Valcic S, Dong Z, Bowden GT. (-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity. Carcinogenesis. 19: 2201-4. PMID 9886579 DOI: 10.1093/Carcin/19.12.2201  0.381
1998 Chen W, Borchers AH, Dong Z, Powell MB, Bowden GT. UVB irradiation-induced activator protein-1 activation correlates with increased c-fos gene expression in a human keratinocyte cell line. The Journal of Biological Chemistry. 273: 32176-81. PMID 9822695 DOI: 10.1074/Jbc.273.48.32176  0.387
1998 Knox JD, Bretton L, Lynch T, Bowden GT, Nagle RB. Synthetic matrix metalloproteinase inhibitor, BB-94, inhibits the invasion of neoplastic human prostate cells in a mouse model. The Prostate. 35: 248-54. PMID 9609547 DOI: 10.1002/(SICI)1097-0045(19980601)35:4<248::AID-PROS3>3.0.CO;2-C  0.344
1997 Klimecki WT, Borchers AH, Egbert RE, Nagle RB, Carter DE, Bowden GT. Effects of acute and chronic arsenic exposure of human-derived keratinocytes in an In Vitro human skin equivalent system: a novel model of human arsenicism. Toxicology in Vitro : An International Journal Published in Association With Bibra. 11: 89-98. PMID 20654299 DOI: 10.1016/S0887-2333(97)00006-4  0.311
1997 Borchers AH, Steinbauer H, Schafer BS, Kramer M, Bowden GT, Fusenig NE. Fibroblast-directed expression and localization of 92-kDa type IV collagenase along the tumor-stroma interface in an in vitro three-dimensional model of human squamous cell carcinoma. Molecular Carcinogenesis. 19: 258-66. PMID 9290703 DOI: 10.1002/(SICI)1098-2744(199708)19:4<258::AID-MC7>3.0.CO;2-8  0.346
1997 Klein RD, Borchers AH, Sundareshan P, Bougelet C, Berkman MR, Nagle RB, Bowden GT. Interleukin-1beta secreted from monocytic cells induces the expression of matrilysin in the prostatic cell line LNCaP. The Journal of Biological Chemistry. 272: 14188-92. PMID 9162049 DOI: 10.1074/jbc.272.22.14188  0.336
1997 Borchers AH, Sanders LA, Powell MB, Bowden GT. Melanocyte mediated paracrine induction of extracellular matrix degrading proteases in squamous cell carcinoma cells. Experimental Cell Research. 231: 61-5. PMID 9056412 DOI: 10.1006/excr.1996.3449  0.419
1997 Borchers AH, Sanders LA, Bowden GT. Regulation of matrilysin expression in cells of squamous cell carcinoma by E-cadherin-mediated cell-cell contact. Journal of Cancer Research and Clinical Oncology. 123: 13-20. PMID 8996535 DOI: 10.1007/BF01212609  0.317
1996 Knox JD, Wolf C, McDaniel K, Clark V, Loriot M, Bowden GT, Nagle RB. Matrilysin expression in human prostate carcinoma. Molecular Carcinogenesis. 15: 57-63. PMID 8561867 DOI: 10.1002/(SICI)1098-2744(199601)15:1<57::AID-MC8>3.0.CO;2-P  0.33
1995 von Bredow DC, Nagle RB, Bowden GT, Cress AE. Degradation of fibronectin fibrils by matrilysin and characterization of the degradation products. Experimental Cell Research. 221: 83-91. PMID 7589259 DOI: 10.1006/Excr.1995.1355  0.39
1994 Wright JH, McDonnell S, Portella G, Bowden GT, Balmain A, Matrisian LM. A switch from stromal to tumor cell expression of stromelysin-1 mRNA associated with the conversion of squamous to spindle carcinomas during mouse skin tumor progression. Molecular Carcinogenesis. 10: 207-15. PMID 8068181 DOI: 10.1002/Mc.2940100405  0.386
1994 Borchers AH, Powell MB, Fusenig NE, Bowden GT. Paracrine factor and cell-cell contact-mediated induction of protease and c-ets gene expression in malignant keratinocyte/dermal fibroblast cocultures. Experimental Cell Research. 213: 143-7. PMID 8020584 DOI: 10.1006/excr.1994.1183  0.377
1994 Wallon UM, Shassetz LR, Cress AE, Bowden GT, Gerner EW. Polyamine-dependent expression of the matrix metalloproteinase matrilysin in a human colon cancer-derived cell line. Molecular Carcinogenesis. 11: 138-44. PMID 7945802 DOI: 10.1002/Mc.2940110304  0.359
1993 Bowden GT, Nelson MA, Levy JP, Finch J, Krieg P. Molecular Mechanisms of Skin Carcinogenesis Induced by Chemicals and Ionizing Radiation Recent Results in Cancer Research. 128: 215-230. PMID 8356321 DOI: 10.1007/978-3-642-84881-0_16  0.36
1992 Bowden GT, Jaffe D, Levy J. Molecular events involved in ionizing radiation induced skin carcinogenesis. Journal of Radiation Research. 226-34. PMID 1823359 DOI: 10.1269/jrr.32.SUPPLEMENT2_226  0.357
1991 Quintanilla M, Haddow S, Jones D, Jaffe D, Bowden GT, Balmain A. Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo Carcinogenesis. 12: 1875-1881. PMID 1934268 DOI: 10.1093/Carcin/12.10.1875  0.334
1990 Craig AM, Bowden GT, Chambers AF, Spearman MA, Greenberg AH, Wright JA, McLeod M, Denhardt DT. Secreted phosphoprotein mRNA is induced during multi-stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts. International Journal of Cancer. Journal International Du Cancer. 46: 133-7. PMID 2365496 DOI: 10.1002/Ijc.2910460124  0.361
1989 Bonham K, Embry T, Gibson D, Jaffe DR, Roberts RA, Cress AE, Bowden GT. Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane. Molecular Carcinogenesis. 2: 34-9. PMID 2567173 DOI: 10.1002/Mc.2940020106  0.366
1988 Krieg P, Finch J, Füstenberger G, Melber K, Matrisian LM, Bowden GT. Tumor promoters induce a transient expression of tumor-associated genes in both basal and differentiated cells of the mouse epidermis. Carcinogenesis. 9: 95-100. PMID 3275504 DOI: 10.1093/carcin/9.1.95  0.354
1985 Dutton DR, Bowden GT. Indirect induction of a clastogenic effect in epidermal cells by a tumor promoter. Carcinogenesis. 6: 1279-84. PMID 4028325 DOI: 10.1093/Carcin/6.9.1279  0.416
1984 Gensler HL, Bowden GT. Evidence suggesting a dissociation of DNA strand scissions and late-stage promotion of tumor cell phenotype. Carcinogenesis. 4: 1507-11. PMID 6652866 DOI: 10.1093/Carcin/4.12.1507  0.418
1984 Lockyer JM, Bowden GT, Kelly MA, Haussler MR, Magun BE. Retinoic acid-induced changes in epidermal growth factor binding and in biological responses mediated by phorbol ester tumor promoter Cancer Letters. 22: 171-182. PMID 6322972 DOI: 10.1016/0304-3835(84)90115-0  0.374
1983 Lockyer JM, Bowden GT, Magun BE. The effect of fluocinolone acetonide and 12-O-tetradecanoyl-phorbol-13-acetate on the binding and biological activity of epidermal growth factor in rat fibroblasts Carcinogenesis. 4: 653-658. PMID 6602667 DOI: 10.1093/carcin/4.6.653  0.313
1981 Matrisian LM, Bowden GT, Magun BE. Mechanism of synergistic induction of DNA synthesis by epidermal growth factor and tumor promoters. Journal of Cellular Physiology. 108: 417-25. PMID 6270169 DOI: 10.1002/Jcp.1041080316  0.393
1980 Magun BE, Bowden GT. Effects of the tumor promoter TPA on the induction of DNA synthesis in normal and RSV-transformed rat fibroblasts. Journal of Supramolecular Structure. 12: 63-72. PMID 232527 DOI: 10.1002/Jss.400120107  0.309
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