Cyrus Vaziri - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Molecular Biology, Cell Biology

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cheng X, An J, Lou J, Gu Q, Ding W, Droby GN, Wang Y, Wang C, Gao Y, Anand JR, Shelton A, Satterlee AB, Mann B, Hsiao YC, Liu CW, ... ... Vaziri C, et al. Trans-lesion synthesis and mismatch repair pathway crosstalk defines chemoresistance and hypermutation mechanisms in glioblastoma. Nature Communications. 15: 1957. PMID 38438348 DOI: 10.1038/s41467-024-45979-5  0.359
2023 Zhang X, Joseph S, Wu D, Bowser JL, Vaziri C. The DNA Damage Response (DDR) landscape of endometrial cancer defines discrete disease subtypes and reveals therapeutic opportunities. Biorxiv : the Preprint Server For Biology. PMID 38045328 DOI: 10.1101/2023.11.20.567919  0.31
2023 Cheng X, An J, Lou J, Gu Q, Ding W, Droby G, Wang Y, Wang C, Gao Y, Shelton A, Satterlee AB, Mann BE, Hsiao YC, Liu CW, Liu K, ... ... Vaziri C, et al. Trans-Lesion Synthesis and Mismatch Repair Pathway Crosstalk Defines Chemoresistance and Hypermutation Mechanisms in Glioblastoma. Biorxiv : the Preprint Server For Biology. PMID 37905107 DOI: 10.1101/2023.10.16.562506  0.354
2023 Cheng X, An J, Lou J, Gu Q, Ding W, Droby G, Wang Y, Wang C, Gao Y, Shelton A, Satterlee A, Mann B, Hsiao YC, Liu CW, Lu K, ... ... Vaziri C, et al. Trans-Lesion Synthesis and Mismatch Repair Pathway Crosstalk Defines Chemoresistance and Hypermutation Mechanisms in Glioblastoma. Research Square. PMID 37886584 DOI: 10.21203/rs.3.rs-2367368/v1  0.359
2023 Lee YS, Klomp JE, Stalnecker CA, Goodwin CM, Gao Y, Droby GN, Vaziri C, Bryant KL, Der CJ, Cox AD. VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in -mutant pancreatic cancer. Genes & Cancer. 14: 30-49. PMID 36923647 DOI: 10.18632/genesandcancer.231  0.391
2023 Anand J, Chiou L, Sciandra C, Zhang X, Hong J, Wu D, Zhou P, Vaziri C. Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy. Nar Cancer. 5: zcad005. PMID 36755961 DOI: 10.1093/narcan/zcad005  0.501
2022 Walens A, Van Alsten SC, Olsson LT, Smith MA, Lockhart A, Gao X, Hamilton AM, Kirk EL, Love MI, Gupta GP, Perou CM, Vaziri C, Hoadley KA, Troester MA. RNA-based classification of homologous recombination deficiency in racially-diverse patients with breast cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 36129803 DOI: 10.1158/1055-9965.EPI-22-0590  0.441
2022 Durando ML, Menghani SV, Baumann JL, Robles DG, Day TA, Vaziri C, Scott AJ. Four-Year Disease-Free Remission in a Patient With POLE Mutation-Associated Colorectal Cancer Treated Using Anti-PD-1 Therapy. Journal of the National Comprehensive Cancer Network : Jnccn. 20: 218-223. PMID 35276675 DOI: 10.6004/jnccn.2021.7115  0.733
2021 Vaziri C, Rogozin IB, Gu Q, Wu D, Day TA. Unravelling roles of error-prone DNA polymerases in shaping cancer genomes. Oncogene. PMID 34663880 DOI: 10.1038/s41388-021-02032-9  0.796
2020 Yan S, Vaziri C. An introduction for the special issue on environmental health and genome integrity. Environmental and Molecular Mutagenesis. PMID 32683747 DOI: 10.1002/Em.22400  0.369
2020 Mustofa MK, Tanoue Y, Tateishi C, Vaziri C, Tateishi S. Roles of Chk2/CHEK2 in guarding against environmentally-induced DNA damage and replication-stress. Environmental and Molecular Mutagenesis. PMID 32578892 DOI: 10.1002/Em.22397  0.654
2020 Lipner MB, Peng XL, Jin C, Xu Y, Gao Y, East MP, Rashid NU, Moffitt RA, Herrera Loeza SG, Morrison AB, Golitz BT, Vaziri C, Graves LM, Johnson GL, Yeh JJ. Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy. Jci Insight. PMID 32213714 DOI: 10.1172/Jci.Insight.129905  0.395
2020 McDonald IM, Grant GD, East MP, Gilbert TS, Wilkerson EM, Goldfarb D, Beri J, Herring LE, Vaziri C, Cook JG, Emanuele MJ, Graves LM. Mass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells. The Journal of Biological Chemistry. PMID 31896573 DOI: 10.1074/Jbc.Ra119.011083  0.377
2020 Wagner BL, Guo J, Gao Y, Vaziri C, Williams SE. Abstract B10: Manipulating translesion synthesis proteins MAGE-A4 and RAD18 in a murine model of oral cancer Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Aacrahns19-B10  0.392
2018 Gao Y, Kardos J, Yang Y, Tamir TY, Mutter-Rottmayer E, Weissman B, Major MB, Kim WY, Vaziri C. The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells. Scientific Reports. 8: 15304. PMID 30333500 DOI: 10.1038/S41598-018-33601-W  0.499
2018 Tanoue Y, Toyoda T, Sun J, Mustofa MK, Tateishi C, Endo S, Motoyama N, Araki K, Wu D, Okuno Y, Tsukamoto T, Takeya M, Ihn H, Vaziri C, Tateishi S. Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure. The Journal of Investigative Dermatology. PMID 29859927 DOI: 10.1016/J.Jid.2018.05.015  0.44
2018 Yang Y, Gao Y, Zlatanou A, Tateishi S, Yurchenko V, Rogozin IB, Vaziri C. Diverse roles of RAD18 and Y-family DNA polymerases in tumorigenesis. Cell Cycle (Georgetown, Tex.). 1-16. PMID 29683380 DOI: 10.1080/15384101.2018.1456296  0.58
2017 Yang Y, Gao Y, Mutter-Rottmayer L, Zlatanou A, Durando M, Ding W, Wyatt D, Ramsden D, Tanoue Y, Tateishi S, Vaziri C. DNA repair factor RAD18 and DNA polymerase Polκ confer tolerance of oncogenic DNA replication stress. The Journal of Cell Biology. PMID 28835467 DOI: 10.1083/Jcb.201702006  0.648
2017 Li J, Liu J, Liang Z, He F, Yang L, Li P, Jiang Y, Wang B, Zhou C, Wang Y, Ren Y, Yang J, Zhang J, Luo Z, Vaziri C, et al. Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth. Cell Death & Disease. 8: e2673. PMID 28300827 DOI: 10.1038/Cddis.2017.46  0.362
2017 Gao Y, Mutter-Rottmayer E, Zlatanou A, Vaziri C, Yang Y. Mechanisms of Post-Replication DNA Repair. Genes. 8. PMID 28208741 DOI: 10.3390/Genes8020064  0.626
2017 Liang Z, Li W, Liu J, Li J, He F, Jiang Y, Yang L, Li P, Wang B, Wang Y, Ren Y, Yang J, Luo Z, Vaziri C, Liu P. Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells. Scientific Reports. 7: 41776. PMID 28150753 DOI: 10.1038/Srep41776  0.528
2016 Mutter-Rottmayer E, Gao Y, Vaziri C. Cancer cells activate damage-tolerant and error-prone DNA synthesis. Molecular & Cellular Oncology. 3: e1225547. PMID 28090576 DOI: 10.1080/23723556.2016.1225547  0.543
2016 Mulvaney KM, Matson JP, Siesser PF, Tamir TY, Goldfarb D, Jacobs TM, Cloer EW, Harrsion JS, Vaziri C, Cook JG, Major MB. Identification and Characterization of MCM3 as a Novel KEAP1 Substrate. The Journal of Biological Chemistry. PMID 27621311 DOI: 10.1074/Jbc.M116.729418  0.376
2016 Gao Y, Mutter-Rottmayer E, Greenwalt AM, Goldfarb D, Yan F, Yang Y, Martinez-Chacin RC, Pearce KH, Tateishi S, Major MB, Vaziri C. A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis. Nature Communications. 7: 12105. PMID 27377895 DOI: 10.1038/Ncomms12105  0.516
2016 Yang Y, Poe JC, Yang L, Fedoriw A, Desai S, Magnuson T, Li Z, Fedoriw Y, Araki K, Gao Y, Tateishi S, Sarantopoulos S, Vaziri C. Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathway in vivo. Nucleic Acids Research. PMID 26883629 DOI: 10.1093/Nar/Gkw072  0.577
2015 Zlatanou A, Sabbioneda S, Miller ES, Greenwalt A, Aggathanggelou A, Maurice MM, Lehmann AR, Stankovic T, Reverdy C, Colland F, Vaziri C, Stewart GS. USP7 is essential for maintaining Rad18 stability and DNA damage tolerance. Oncogene. PMID 25961918 DOI: 10.1038/Onc.2015.149  0.609
2014 Cheng Z, DiMichele LA, Rojas M, Vaziri C, Mack CP, Taylor JM. Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.). Journal of Molecular and Cellular Cardiology. 67: 1-11. PMID 24342076 DOI: 10.1016/J.Yjmcc.2013.12.002  0.331
2013 Bakkenist CJ, Vaziri C. Stoichiometry of ubiquitin-binding proteins directs DSB repair. Cell Cycle (Georgetown, Tex.). 12: 3716-7. PMID 24189535 DOI: 10.4161/Cc.26963  0.622
2013 Durando M, Tateishi S, Vaziri C. A non-catalytic role of DNA polymerase η in recruiting Rad18 and promoting PCNA monoubiquitination at stalled replication forks. Nucleic Acids Research. 41: 3079-93. PMID 23345618 DOI: 10.1093/Nar/Gkt016  0.636
2013 Yang Y, Durando M, Smith-Roe SL, Sproul C, Greenwalt AM, Kaufmann W, Oh S, Hendrickson EA, Vaziri C. Cell cycle stage-specific roles of Rad18 in tolerance and repair of oxidative DNA damage. Nucleic Acids Research. 41: 2296-312. PMID 23295675 DOI: 10.1093/Nar/Gks1325  0.57
2012 Whitehurst CB, Vaziri C, Shackelford J, Pagano JS. Epstein-Barr virus BPLF1 deubiquitinates PCNA and attenuates polymerase η recruitment to DNA damage sites. Journal of Virology. 86: 8097-106. PMID 22623772 DOI: 10.1128/Jvi.00588-12  0.614
2012 Barkley LR, Palle K, Durando M, Day TA, Gurkar A, Kakusho N, Li J, Masai H, Vaziri C. c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks. Molecular Biology of the Cell. 23: 1943-54. PMID 22456510 DOI: 10.1091/Mbc.E11-10-0829  0.79
2011 Day TA, Sproul C, Cordeiro-Stone M, Vaziri C. Analyzing DNA replication dynamics of genotoxin-treated cells using velocity sedimentation. Methods in Molecular Biology (Clifton, N.J.). 782: 159-70. PMID 21870290 DOI: 10.1007/978-1-61779-273-1_11  0.822
2011 Palle K, Vaziri C. Rad18 E3 ubiquitin ligase activity mediates Fanconi anemia pathway activation and cell survival following DNA Topoisomerase 1 inhibition. Cell Cycle (Georgetown, Tex.). 10: 1625-38. PMID 21478670 DOI: 10.4161/Cc.10.10.15617  0.65
2011 Williams SA, Longerich S, Sung P, Vaziri C, Kupfer GM. The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI. Blood. 117: 5078-87. PMID 21355096 DOI: 10.1182/Blood-2010-10-311761  0.496
2010 Vaziri C. Linking Cdc7 with the replication checkpoint. Cell Cycle (Georgetown, Tex.). 9: 4787. PMID 21248484 DOI: 10.4161/Cc.9.24.14167  0.455
2010 Vaziri C, Masai H. Integrating DNA replication with trans-lesion synthesis via Cdc7. Cell Cycle (Georgetown, Tex.). 9: 4818-23. PMID 21150323 DOI: 10.4161/Cc.9.24.14241  0.665
2010 Day TA, Palle K, Barkley LR, Kakusho N, Zou Y, Tateishi S, Verreault A, Masai H, Vaziri C. Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication. The Journal of Cell Biology. 191: 953-66. PMID 21098111 DOI: 10.1083/Jcb.201006043  0.827
2010 Wong PG, Glozak MA, Cao TV, Vaziri C, Seto E, Alexandrow M. Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin. Cell Cycle (Georgetown, Tex.). 9: 4351-63. PMID 20980834 DOI: 10.4161/Cc.9.21.13596  0.415
2010 Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM, Vaziri C. Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. The Journal of Biological Chemistry. 285: 31525-36. PMID 20675655 DOI: 10.1074/Jbc.M110.138206  0.814
2010 Song IY, Barkley LR, Day TA, Weiss RS, Vaziri C. A novel role for Fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells. Cell Cycle (Georgetown, Tex.). 9: 2375-88. PMID 20519958 DOI: 10.4161/Cc.9.12.11900  0.808
2010 Wu J, Qian J, Li C, Kwok L, Cheng F, Liu P, Perdomo C, Kotton D, Vaziri C, Anderlind C, Spira A, Cardoso WV, Lü J. miR-129 regulates cell proliferation by downregulating Cdk6 expression. Cell Cycle (Georgetown, Tex.). 9: 1809-18. PMID 20404570 DOI: 10.4161/Cc.9.9.11535  0.301
2009 Ohmori H, Hanafusa T, Ohashi E, Vaziri C. Separate roles of structured and unstructured regions of Y-family DNA polymerases. Advances in Protein Chemistry and Structural Biology. 78: 99-146. PMID 20663485 DOI: 10.1016/S1876-1623(08)78004-0  0.512
2009 Day T, Vaziri C. HPV E6 oncoprotein prevents recovery of stalled replication forks independently of p53 degradation. Cell Cycle (Georgetown, Tex.). 8: 2138. PMID 19587541 DOI: 10.4161/Cc.8.14.9028  0.712
2009 Barkley LR, Song IY, Zou Y, Vaziri C. Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells. Cell Cycle (Georgetown, Tex.). 8: 1577-88. PMID 19377277 DOI: 10.4161/Cc.8.10.8535  0.82
2009 Ohashi E, Hanafusa T, Kamei K, Song I, Tomida J, Hashimoto H, Vaziri C, Ohmori H. Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 14: 101-11. PMID 19170759 DOI: 10.1111/J.1365-2443.2008.01255.X  0.512
2009 Liu P, Pazin DE, Merson RR, Albrecht KH, Vaziri C. The developmentally-regulated Smoc2 gene is repressed by Aryl-hydrocarbon receptor (Ahr) signaling. Gene. 433: 72-80. PMID 19146932 DOI: 10.1016/J.Gene.2008.12.010  0.31
2009 Liu P, Slater DM, Lenburg M, Nevis K, Cook JG, Vaziri C. Replication licensing promotes cyclin D1 expression and G1 progression in untransformed human cells Cell Cycle. 8: 125-136. PMID 19106611 DOI: 10.4161/Cc.8.1.7528  0.757
2008 Foy RL, Song IY, Chitalia VC, Cohen HT, Saksouk N, Cayrou C, Vaziri C, Côté J, Panchenko MV. Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex. The Journal of Biological Chemistry. 283: 28817-26. PMID 18684714 DOI: 10.1074/Jbc.M801407200  0.698
2008 Tomida J, Masuda Y, Hiroaki H, Ishikawa T, Song I, Tsurimoto T, Tateishi S, Shiomi T, Kamei Y, Kim J, Kamiya K, Vaziri C, Ohmori H, Todo T. DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex. The Journal of Biological Chemistry. 283: 9071-9. PMID 18245774 DOI: 10.1074/Jbc.M709835200  0.644
2008 Liu P, Lu J, Cardoso WV, Vaziri C. The SPARC-related factor SMOC-2 promotes growth factor-induced cyclin D1 expression and DNA synthesis via integrin-linked kinase. Molecular Biology of the Cell. 19: 248-61. PMID 17989364 DOI: 10.1091/Mbc.E07-05-0510  0.472
2007 Barkley LR, Ohmori H, Vaziri C. Integrating S-phase checkpoint signaling with trans-lesion synthesis of bulky DNA adducts. Cell Biochemistry and Biophysics. 47: 392-408. PMID 17652783 DOI: 10.1007/S12013-007-0032-7  0.632
2006 Liu P, Barkley LR, Day T, Bi X, Slater DM, Alexandrow MG, Nasheuer HP, Vaziri C. The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism. The Journal of Biological Chemistry. 281: 30631-44. PMID 16912045 DOI: 10.1074/Jbc.M602982200  0.813
2006 Rocnik EF, Liu P, Sato K, Walsh K, Vaziri C. The novel SPARC family member SMOC-2 potentiates angiogenic growth factor activity. The Journal of Biological Chemistry. 281: 22855-64. PMID 16774925 DOI: 10.1074/Jbc.M513463200  0.364
2006 Bi X, Barkley LR, Slater DM, Tateishi S, Yamaizumi M, Ohmori H, Vaziri C. Rad18 regulates DNA polymerase kappa and is required for recovery from S-phase checkpoint-mediated arrest. Molecular and Cellular Biology. 26: 3527-40. PMID 16611994 DOI: 10.1128/Mcb.26.9.3527-3540.2006  0.793
2005 Bi X, Slater DM, Ohmori H, Vaziri C. DNA polymerase kappa is specifically required for recovery from the benzo[a]pyrene-dihydrodiol epoxide (BPDE)-induced S-phase checkpoint. The Journal of Biological Chemistry. 280: 22343-55. PMID 15817457 DOI: 10.1074/Jbc.M501562200  0.767
2003 Vaziri C, Saxena S, Jeon Y, Lee C, Murata K, Machida Y, Wagle N, Hwang DS, Dutta A. A p53-dependent checkpoint pathway prevents rereplication. Molecular Cell. 11: 997-1008. PMID 12718885 DOI: 10.1016/S1097-2765(03)00099-6  0.526
2003 Weiss RS, Leder P, Vaziri C. Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint. Molecular and Cellular Biology. 23: 791-803. PMID 12529385 DOI: 10.1128/Mcb.23.3.791-803.2003  0.651
2003 Vaziri C, Saxena S, Jeon Y, Lee C, Murata K, Machida Y, Wagle N, Hwang DS, Dutta A. Erratum: A p53-dependent checkpoint pathway prevents rereplication (Molecular Cell (April 2003) 11 (997-1008)) Molecular Cell. 11. DOI: 10.1016/S1097-2765(03)00202-8  0.343
2002 Guo N, Faller DV, Vaziri C. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 13: 77-86. PMID 11864911  0.391
2001 Nghiem P, Park PK, Kim Y, Vaziri C, Schreiber SL. ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation. Proceedings of the National Academy of Sciences of the United States of America. 98: 9092-7. PMID 11481475 DOI: 10.1073/Pnas.161281798  0.558
2000 Hsing A, Faller DV, Vaziri C. DNA-damaging aryl hydrocarbons induce Mdm2 expression via p53-independent post-transcriptional mechanisms. The Journal of Biological Chemistry. 275: 26024-31. PMID 10856296 DOI: 10.1074/Jbc.M002455200  0.513
2000 Guo N, Faller DV, Vaziri C. A novel DNA damage checkpoint involving post-transcriptional regulation of cyclin A expression. The Journal of Biological Chemistry. 275: 1715-22. PMID 10636867 DOI: 10.1074/Jbc.275.3.1715  0.599
1997 Vaziri C, Faller DV. A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. The Journal of Biological Chemistry. 272: 2762-9. PMID 9006915 DOI: 10.1074/Jbc.272.5.2762  0.431
1996 Vaziri C, Schneider A, Sherr DH, Faller DV. Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts. The Journal of Biological Chemistry. 271: 25921-7. PMID 8824226 DOI: 10.1074/Jbc.271.42.25921  0.387
1996 Vaziri C, Faller DV. Down-regulation of platelet-derived growth factor receptor expression during terminal differentiation of 3T3-L1 pre-adipocyte fibroblasts. The Journal of Biological Chemistry. 271: 13642-8. PMID 8662875 DOI: 10.1074/Jbc.271.23.13642  0.33
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