| Year |
Citation |
Score |
| 2023 |
Pryce BR, Wang DJ, Zimmers TA, Ostrowski MC, Guttridge DC. Cancer cachexia: involvement of an expanding macroenvironment. Cancer Cell. PMID 36868225 DOI: 10.1016/j.ccell.2023.02.007 |
0.445 |
|
| 2022 |
Jengelley DHA, Wang M, Narasimhan A, Rupert JE, Young AR, Zhong X, Horan DJ, Robling AG, Koniaris LG, Zimmers TA. Exogenous Oncostatin M induces Cardiac Dysfunction, Musculoskeletal Atrophy, and Fibrosis. Cytokine. 159: 155972. PMID 36054964 DOI: 10.1016/j.cyto.2022.155972 |
0.465 |
|
| 2022 |
Cirillo F, Zimmers TA, Mangiavini L. Editorial: Metabolic Adaptation of Muscle Tissue in Diseases Associated With Cachexia. Frontiers in Cell and Developmental Biology. 10: 947902. PMID 35721487 DOI: 10.3389/fcell.2022.947902 |
0.367 |
|
| 2022 |
Loumaye A, Lause P, Zhong X, Zimmers TA, Bindels LB, Thissen JP. Activin A Causes Muscle Atrophy through MEF2C-Dependent Impaired Myogenesis. Cells. 11. PMID 35406681 DOI: 10.3390/cells11071119 |
0.404 |
|
| 2022 |
Gaafer OU, Zimmers TA. Nutrition challenges of cancer cachexia. Jpen. Journal of Parenteral and Enteral Nutrition. 45: 16-25. PMID 34897740 DOI: 10.1002/jpen.2287 |
0.353 |
|
| 2021 |
Pin F, Jones AJ, Huot JR, Narasimhan A, Zimmers TA, Bonewald LF, Bonetto A. RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non-Metastatic Ovarian Cancer in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 34904285 DOI: 10.1002/jbmr.4480 |
0.431 |
|
| 2021 |
Zimmers TA. Tumours block protective muscle and nerve signals to cause cachexia. Nature. 598: 37-38. PMID 34548663 DOI: 10.1038/d41586-021-02492-9 |
0.367 |
|
| 2021 |
Wang R, Bhat-Nakshatri P, Zhong X, Zimmers T, Nakshatri H. Hormonally regulated myogenic miR-486 influences sex-specific differences in cancer-induced skeletal muscle defects. Endocrinology. PMID 34265069 DOI: 10.1210/endocr/bqab142 |
0.448 |
|
| 2021 |
Narasimhan A, Zhong X, Au EP, Ceppa EP, Nakeeb A, House MG, Zyromski NJ, Schmidt CM, Schloss KNH, Schloss DEI, Liu Y, Jiang G, Hancock BA, Radovich M, Kays JK, ... ... Zimmers TA, et al. Profiling of Adipose and Skeletal Muscle in Human Pancreatic Cancer Cachexia Reveals Distinct Gene Profiles with Convergent Pathways. Cancers. 13. PMID 33923976 DOI: 10.3390/cancers13081975 |
0.469 |
|
| 2021 |
Rupert JE, Narasimhan A, Jengelley DHA, Jiang Y, Liu J, Au E, Silverman LM, Sandusky G, Bonetto A, Cao S, Lu X, O'Connell TM, Liu Y, Koniaris LG, Zimmers TA. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia. The Journal of Experimental Medicine. 218. PMID 33851955 DOI: 10.1084/jem.20190450 |
0.447 |
|
| 2021 |
Wang R, Kumar B, Bhat-Nakshatri P, Prasad MS, Jacobsen MH, Ovalle G, Maguire C, Sandusky G, Trivedi T, Mohammad KS, Guise T, Penthala NR, Crooks PA, Liu J, Zimmers T, et al. Aging-associated skeletal muscle defects in HER2/Neu transgenic mammary tumor model. Jcsm Rapid Communications. 4: 24-39. PMID 33842876 DOI: 10.1002/rco2.23 |
0.6 |
|
| 2021 |
Fallon M, Gallouzi IE, Guttridge DC, Zimmers TA. Editorial: Highlights from the 2020 virtual cancer cachexia conference. Current Opinion in Supportive and Palliative Care. 15: 48-49. PMID 33470683 DOI: 10.1097/SPC.0000000000000540 |
0.319 |
|
| 2020 |
Narasimhan A, Shahda S, Kays JK, Perkins SM, Cheng L, Schloss KNH, Schloss DEI, Koniaris LG, Zimmers TA. Identification of Potential Serum Protein Biomarkers and Pathways for Pancreatic Cancer Cachexia Using an Aptamer-Based Discovery Platform. Cancers. 12. PMID 33334063 DOI: 10.3390/cancers12123787 |
0.331 |
|
| 2020 |
Caston RA, Shah F, Starcher CL, Wireman R, Babb O, Grimard M, McGeown J, Armstrong L, Tong Y, Pili R, Rupert J, Zimmers TA, Elmi AN, Pollok KE, Motea EA, et al. Combined inhibition of Ref-1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co-culture models. Journal of Cellular and Molecular Medicine. PMID 33274592 DOI: 10.1111/jcmm.16132 |
0.31 |
|
| 2020 |
Huot JR, Pin F, Narasimhan A, Novinger LJ, Keith AS, Zimmers TA, Willis MS, Bonetto A. ACVR2B antagonism as a countermeasure to multi-organ perturbations in metastatic colorectal cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle. PMID 33200567 DOI: 10.1002/jcsm.12642 |
0.483 |
|
| 2020 |
Shamseddeen H, Madathanapalli A, Are VS, Shah VH, Sanyal AJ, Tang Q, Liang T, Gelow K, Zimmers TA, Chalasani N, Desai AP. Changes in Serum Myostatin Levels in Alcoholic Hepatitis Correlate with Improvement in MELD. Digestive Diseases and Sciences. PMID 33074470 DOI: 10.1007/s10620-020-06632-5 |
0.317 |
|
| 2020 |
Zhong X, Zimmers TA. Sex Differences in Cancer Cachexia. Current Osteoporosis Reports. PMID 33044689 DOI: 10.1007/s11914-020-00628-w |
0.457 |
|
| 2020 |
Kays JK, Koniaris LG, Cooper CA, Pili R, Jiang G, Liu Y, Zimmers TA. The Combination of Low Skeletal Muscle Mass and High Tumor Interleukin-6 Associates with Decreased Survival in Clear Cell Renal Cell Carcinoma. Cancers. 12. PMID 32560494 DOI: 10.3390/Cancers12061605 |
0.351 |
|
| 2020 |
Huot JR, Novinger LJ, Pin F, Narasimhan A, Zimmers TA, O'Connell TM, Bonetto A. Formation of colorectal liver metastases induces musculoskeletal and metabolic abnormalities consistent with exacerbated cachexia. Jci Insight. PMID 32298240 DOI: 10.1172/jci.insight.136687 |
0.361 |
|
| 2020 |
Rupert JE, Jengelley DHA, Zimmers TA. In Vitro, In Vivo, and In Silico Methods for assessment of Muscle Size and Muscle Growth Regulation. Shock (Augusta, Ga.). PMID 31939770 DOI: 10.1097/SHK.0000000000001498 |
0.538 |
|
| 2019 |
Aguilar-Perez A, Pacheco-Costa R, Atkinson EG, Deosthale P, Davis HM, Essex AL, Dilley JE, Gomez L, Rupert JE, Zimmers TA, Thompson RJ, Allen MR, Plotkin LI. Age- and sex-dependent role of osteocytic pannexin1 on bone and muscle mass and strength. Scientific Reports. 9: 13903. PMID 31554905 DOI: 10.1038/s41598-019-50444-1 |
0.372 |
|
| 2019 |
Zhong X, Pons M, Poirier C, Jiang Y, Liu J, Sandusky GE, Shahda S, Nakeeb A, Schmidt CM, House MG, Ceppa EP, Zyromski NJ, Liu Y, Jiang G, Couch ME, ... ... Zimmers TA, et al. The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy. Journal of Cachexia, Sarcopenia and Muscle. PMID 31286691 DOI: 10.1002/Jcsm.12461 |
0.3 |
|
| 2019 |
Rupert JE, Koniaris LG, Zimmers TA. Multimodal Action of Mas Activation for Systemic Cancer Cachexia Therapy. Cancer Research. 79: 699-700. PMID 30770364 DOI: 10.1158/0008-5472.CAN-18-3910 |
0.483 |
|
| 2018 |
Pin F, Barreto R, Kitase Y, Mitra S, Erne CE, Novinger LJ, Zimmers TA, Couch ME, Bonewald LF, Bonetto A. Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle. PMID 30009406 DOI: 10.1002/Jcsm.12311 |
0.426 |
|
| 2018 |
Talbert EE, Lewis HL, Farren MR, Ramsey ML, Chakedis JM, Rajasekera P, Haverick E, Sarna A, Bloomston M, Pawlik TM, Zimmers TA, Lesinski GB, Hart PA, Dillhoff ME, Schmidt CR, et al. Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naïve pancreatic cancer patients. Journal of Cachexia, Sarcopenia and Muscle. PMID 29316343 DOI: 10.1002/Jcsm.12251 |
0.308 |
|
| 2017 |
Wang R, Bhat-Nakshatri P, Padua MB, Prasad MS, Anjanappa M, Jacobson M, Finnearty C, Sefcsik V, McElyea K, Redmond R, Sandusky GE, Penthala N, Crooks PA, Liu J, Zimmers T, et al. Pharmacological dual inhibition of tumor and tumor-induced functional limitations in transgenic model of breast cancer. Molecular Cancer Therapeutics. PMID 28978719 DOI: 10.1158/1535-7163.Mct-17-0717 |
0.557 |
|
| 2017 |
Zimmers TA, Jiang Y, Wang M, Liang TW, Rupert JE, Au ED, Marino FE, Couch ME, Koniaris LG. Erratum to: Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting. Basic Research in Cardiology. 112: 53. PMID 28721633 DOI: 10.1007/s00395-017-0642-1 |
0.47 |
|
| 2017 |
Zimmers TA, Jiang Y, Wang M, Liang TW, Rupert JE, Au ED, Marino FE, Couch ME, Koniaris LG. Exogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting. Basic Research in Cardiology. 112: 48. PMID 28647906 DOI: 10.1007/s00395-017-0639-9 |
0.497 |
|
| 2017 |
Milgrom DP, Lad NL, Koniaris LG, Zimmers TA. Bone Pain and Muscle Weakness in Cancer Patients. Current Osteoporosis Reports. PMID 28497213 DOI: 10.1007/s11914-017-0354-3 |
0.423 |
|
| 2017 |
Camperi A, Pin F, Costamagna D, Penna F, Menduina ML, Aversa Z, Zimmers T, Verzaro R, Fittipaldi R, Caretti G, Baccino FM, Muscaritoli M, Costelli P. Vitamin D and VDR in cancer cachexia and muscle regeneration. Oncotarget. 8: 21778-21793. PMID 28423519 DOI: 10.18632/Oncotarget.15583 |
0.47 |
|
| 2017 |
Sato AY, Richardson D, Cregor M, Davis HM, Au ED, McAndrews K, Zimmers TA, Organ JM, Peacock M, Plotkin LI, Bellido T. Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases. Endocrinology. 158: 664-677. PMID 28359087 DOI: 10.1210/En.2016-1779 |
0.404 |
|
| 2017 |
Wang R, Nakshatri P, Padua M, Anjanappa M, Penthala N, Crook P, Liu J, Zimmers T, Nakshatri H. Abstract P6-15-03: Dual targeting of mammary tumors and tumor-associated functional limitations through inhibition of NF-kB Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P6-15-03 |
0.572 |
|
| 2016 |
Au ED, Desai AP, Koniaris LG, Zimmers TA. The MEK-Inhibitor Selumetinib Attenuates Tumor Growth and Reduces IL-6 Expression but Does Not Protect against Muscle Wasting in Lewis Lung Cancer Cachexia. Frontiers in Physiology. 7: 682. PMID 28149280 DOI: 10.3389/fphys.2016.00682 |
0.598 |
|
| 2016 |
Bonetto A, Kays JK, Parker VA, Matthews RR, Barreto R, Puppa MJ, Kang KS, Carson JA, Guise TA, Mohammad KS, Robling AG, Couch ME, Koniaris LG, Zimmers TA. Differential Bone Loss in Mouse Models of Colon Cancer Cachexia. Frontiers in Physiology. 7: 679. PMID 28123369 DOI: 10.3389/fphys.2016.00679 |
0.377 |
|
| 2016 |
Bonetto A, Rupert JE, Barreto R, Zimmers TA. The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia. Journal of Visualized Experiments : Jove. PMID 27929469 DOI: 10.3791/54893 |
0.63 |
|
| 2016 |
Barreto R, Mandili G, Witzmann FA, Novelli F, Zimmers TA, Bonetto A. Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways. Frontiers in Physiology. 7: 472. PMID 27807421 DOI: 10.3389/fphys.2016.00472 |
0.559 |
|
| 2016 |
Ogunbileje JO, Porter C, Herndon DN, Chao T, Abdelrahman DR, Papadimitriou A, Chondronikola M, Zimmers TA, Reidy PT, Rasmussen BB, Sidossis LS. Hypermetabolism and Hypercatabolism of Skeletal Muscle Accompany Mitochondrial Stress Following Severe Burn Trauma. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00535.2015. PMID 27382037 DOI: 10.1152/Ajpendo.00535.2015 |
0.335 |
|
| 2016 |
Barreto R, Waning DL, Gao H, Liu Y, Zimmers TA, Bonetto A. Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs. Oncotarget. PMID 27259276 DOI: 10.18632/Oncotarget.9779 |
0.587 |
|
| 2016 |
Zimmers TA, Fishel ML, Bonetto A. STAT3 in the systemic inflammation of cancer cachexia. Seminars in Cell & Developmental Biology. 54: 28-41. PMID 26860754 DOI: 10.1016/j.semcdb.2016.02.009 |
0.613 |
|
| 2015 |
Mace T, Shakya R, Pitarresi J, Loftus S, Swanson B, Young G, Zhong X, Zimmers T, Ostrowski M, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski G. Anti-IL-6 and PD-L1 antibody combination therapy reduces tumor progression in murine models of pancreatic cancer Journal For Immunotherapy of Cancer. 3. DOI: 10.1186/2051-1426-3-S2-P366 |
0.346 |
|
| 2014 |
Guttridge D, Couch M, Di Marco S, Gallouzi IE, Zitzmann ND, Baracos V, Rudnicki M, Tremblay M, Zimmers T. An invitation to the 2nd Cancer Cachexia Conference, Montréal, Canada. Journal of Cachexia, Sarcopenia and Muscle. 5: 181. PMID 24965540 DOI: 10.1007/S13539-014-0150-1 |
0.456 |
|
| 2014 |
Munoz J, Cheng G, Pedroso F, Spalding P, Morris C, Bialek P, St. Andre M, Puppa M, Carson J, Koniaris L, Zimmers T. Biologicals Targeting Myostatin/GDF-11/Activins Prevent Burn-Induced Muscle Loss in Mice Journal of Surgical Research. 186: 591-592. DOI: 10.1016/j.jss.2013.11.545 |
0.478 |
|
| 2012 |
Bonetto A, Aydogdu T, Jin X, Zhang Z, Zhan R, Puzis L, Koniaris LG, Zimmers TA. JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia. American Journal of Physiology. Endocrinology and Metabolism. 303: E410-21. PMID 22669242 DOI: 10.1152/Ajpendo.00039.2012 |
0.709 |
|
| 2012 |
Wang X, Pickrell AM, Zimmers TA, Moraes CT. Increase in muscle mitochondrial biogenesis does not prevent muscle loss but increased tumor size in a mouse model of acute cancer-induced cachexia. Plos One. 7: e33426. PMID 22428048 DOI: 10.1371/Journal.Pone.0033426 |
0.587 |
|
| 2011 |
Bonetto A, Aydogdu T, Kunzevitzky N, Guttridge DC, Khuri S, Koniaris LG, Zimmers TA. STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia. Plos One. 6: e22538. PMID 21799891 DOI: 10.1371/Journal.Pone.0022538 |
0.69 |
|
| 2010 |
Lee SJ, Lee YS, Zimmers TA, Soleimani A, Matzuk MM, Tsuchida K, Cohn RD, Barton ER. Regulation of muscle mass by follistatin and activins. Molecular Endocrinology (Baltimore, Md.). 24: 1998-2008. PMID 20810712 DOI: 10.1210/me.2010-0127 |
0.584 |
|
| 2010 |
Benny Klimek ME, Aydogdu T, Link MJ, Pons M, Koniaris LG, Zimmers TA. Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia. Biochemical and Biophysical Research Communications. 391: 1548-54. PMID 20036643 DOI: 10.1016/J.Bbrc.2009.12.123 |
0.71 |
|
| 2009 |
Cheung M, Spalding P, Namias N, Koniaris L, Zimmers T. QS204. A Murine Model of Chronic Muscle Wasting Induced by Burn Injury Journal of Surgical Research. 151: 291. DOI: 10.1016/j.jss.2008.11.505 |
0.366 |
|
| 2009 |
Cheung M, Spalding P, Namias N, Koniaris L, Zimmers T. QS202. The Skeletal Muscle Myostatin/ACVR2B Pathway is Essential for Recovery From Burn Injury Journal of Surgical Research. 151: 291. DOI: 10.1016/j.jss.2008.11.503 |
0.415 |
|
| 2008 |
Link M, Aydogdu T, Guo S, Koniaris LG, Zimmers TA. QS99. Genetic and Pharmacologic Inhibition of Myostatin for Muscle Preservation in Cancer Cachexia Journal of Surgical Research. 144: 307. DOI: 10.1016/J.Jss.2007.12.339 |
0.699 |
|
| 2007 |
Zimmers TA, Gutierrez JC, Koniaris LG. NAG-1/GDF-15: no evidence for an inhibitory role in colon cancer? Gastroenterology. 132: 1204-5; author reply. PMID 17383450 DOI: 10.1053/j.gastro.2007.02.010 |
0.307 |
|
| 2007 |
Gutierrez JC, Koniaris L, Jin X, Zimmers T. GDF-15 mediates the anti-tumorigenic effects of NSAIDs in intestinal cancers Journal of the American College of Surgeons. 205: S37. DOI: 10.1016/J.Jamcollsurg.2007.06.084 |
0.319 |
|
| 2002 |
Zimmers TA, Davies MV, Koniaris LG, Haynes P, Esquela AF, Tomkinson KN, McPherron AC, Wolfman NM, Lee SJ. Induction of cachexia in mice by systemically administered myostatin. Science (New York, N.Y.). 296: 1486-8. PMID 12029139 DOI: 10.1126/Science.1069525 |
0.52 |
|
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