Inaki Sanz - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Immunology, Cell Biology

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Corrado A, Ramonell RP, Woodruff MC, Tipton C, Wise S, Levy J, DelGaudio J, Kuruvilla ME, Magliocca KR, Tomar D, Garimalla S, Scharer CD, Boss JM, Wu H, Gumber S, ... ... Sanz I, et al. Extrafollicular IgD+ B cells generate IgE antibody secreting cells in the nasal mucosa. Mucosal Immunology. PMID 34050324 DOI: 10.1038/s41385-021-00410-w  0.596
2020 Haddad NS, Nguyen DC, Kuruvilla ME, Morrison-Porter A, Anam F, Cashman KS, Ramonell RP, Kyu S, Saini AS, Cabrera-Mora M, Derrico A, Alter D, Roback JD, Horwath M, O'Keefe JB, ... ... Sanz I, et al. Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection. Biorxiv : the Preprint Server For Biology. PMID 33299998 DOI: 10.1101/2020.12.04.410589  0.303
2020 Yang X, Tipton CM, Woodruff MC, Zhou E, Lee FE, Sanz I, Qiu P. GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data. Bmc Genomics. 21: 583. PMID 32900378 DOI: 10.1186/S12864-020-06936-W  0.416
2019 Cashman KS, Jenks SA, Woodruff MC, Tomar D, Tipton CM, Scharer CD, Eun-Hyung Lee F, Boss JM, Sanz I. Understanding and measuring human B-cell tolerance and its breakdown in autoimmune disease. Immunological Reviews. PMID 31755562 DOI: 10.1111/Imr.12820  0.536
2019 Nguyen DC, Joyner CJ, Sanz I, Lee FE. Factors Affecting Early Antibody Secreting Cell Maturation Into Long-Lived Plasma Cells. Frontiers in Immunology. 10: 2138. PMID 31572364 DOI: 10.3389/fimmu.2019.02138  0.404
2019 Scharer CD, Blalock EL, Mi T, Barwick BG, Jenks SA, Deguchi T, Cashman KS, Neary BE, Patterson DG, Hicks SL, Khosroshahi A, Eun-Hyung Lee F, Wei C, Sanz I, Boss JM. Epigenetic programming underpins B cell dysfunction in human SLE. Nature Immunology. PMID 31263277 DOI: 10.1038/s41590-019-0419-9  0.608
2019 Zumaquero E, Stone SL, Scharer CD, Jenks SA, Nellore A, Mousseau B, Rosal-Vela A, Botta D, Bradley JE, Wojciechowski W, Ptacek T, Danila MI, Edberg JC, Bridges SL, Kimberly RP, ... ... Sanz I, et al. IFNγ induces epigenetic programming of human T-bet B cells and promotesTLR7/8 and IL-21 induced differentiation. Elife. 8. PMID 31090539 DOI: 10.7554/Elife.41641  0.437
2019 Garimilla S, Nguyen DC, Halliley JL, Tipton C, Rosenberg AF, Fucile CF, Saney CL, Kyu S, Kaminski D, Qian Y, Scheuermann RH, Gibson G, Sanz I, Lee FE. Differential transcriptome and development of human peripheral plasma cell subsets. Jci Insight. 4. PMID 31045577 DOI: 10.1172/Jci.Insight.126732  0.363
2018 Tipton CM, Hom JR, Fucile CF, Rosenberg AF, Sanz I. Understanding B-cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B-cell immunomics approach. Immunological Reviews. 284: 120-131. PMID 29944759 DOI: 10.1111/imr.12660  0.603
2018 Upadhyay AA, Kauffman RC, Wolabaugh AN, Cho A, Patel NB, Reiss SM, Havenar-Daughton C, Dawoud RA, Tharp GK, Sanz I, Pulendran B, Crotty S, Lee FE, Wrammert J, Bosinger SE. BALDR: a computational pipeline for paired heavy and light chain immunoglobulin reconstruction in single-cell RNA-seq data. Genome Medicine. 10: 20. PMID 29558968 DOI: 10.1186/S13073-018-0528-3  0.358
2017 Oleksyn D, Zhao J, Vosoughi A, Zhao JC, Misra R, Pentland AP, Ryan D, Anolik J, Ritchlin C, Looney J, Anandarajah AP, Schwartz G, Calvi LM, Georger M, Mohan C, ... Sanz I, et al. PKK deficiency in B cells prevents lupus development in Sle lupus mice. Immunology Letters. PMID 28274793 DOI: 10.1016/J.Imlet.2017.03.002  0.656
2015 Adlowitz DG, Barnard J, Biear JN, Cistrone C, Owen T, Wang W, Palanichamy A, Ezealah E, Campbell D, Wei C, Looney RJ, Sanz I, Anolik JH. Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response. Plos One. 10: e0128269. PMID 26047509 DOI: 10.1371/journal.pone.0128269  0.588
2015 Tipton CM, Fucile CF, Darce J, Chida A, Ichikawa T, Gregoretti I, Schieferl S, Hom J, Jenks S, Feldman RJ, Mehr R, Wei C, Lee FE, Cheung WC, Rosenberg AF, ... Sanz I, et al. Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. Nature Immunology. 16: 755-65. PMID 26006014 DOI: 10.1038/ni.3175  0.518
2015 Portugal S, Tipton CM, Sohn H, Kone Y, Wang J, Li S, Skinner J, Virtaneva K, Sturdevant DE, Porcella SF, Doumbo OK, Doumbo S, Kayentao K, Ongoiba A, Traore B, ... Sanz I, et al. Malaria-associated atypical memory B cells exhibit markedly reduced B cell receptor signaling and effector function. Elife. 4. PMID 25955968 DOI: 10.7554/Elife.07218  0.476
2015 Wei C, Jenks S, Sanz I. Polychromatic flow cytometry in evaluating rheumatic disease patients. Arthritis Research & Therapy. 17: 46. PMID 25880288 DOI: 10.1186/s13075-015-0561-1  0.502
2014 Roberts ME, Kaminski D, Jenks SA, Maguire C, Ching K, Burbelo PD, Iadarola MJ, Rosenberg A, Coca A, Anolik J, Sanz I. Primary Sjögren's syndrome is characterized by distinct phenotypic and transcriptional profiles of IgD+ unswitched memory B cells. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2558-69. PMID 24909310 DOI: 10.1002/Art.38734  0.497
2014 Sanz I. Rationale for B cell targeting in SLE. Seminars in Immunopathology. 36: 365-75. PMID 24763533 DOI: 10.1007/S00281-014-0430-Z  0.706
2014 Palanichamy A, Bauer JW, Yalavarthi S, Meednu N, Barnard J, Owen T, Cistrone C, Bird A, Rabinovich A, Nevarez S, Knight JS, Dedrick R, Rosenberg A, Wei C, Rangel-Moreno J, ... ... Sanz I, et al. Neutrophil-mediated IFN activation in the bone marrow alters B cell development in human and murine systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 192: 906-18. PMID 24379124 DOI: 10.4049/Jimmunol.1302112  0.55
2012 Coca A, Sanz I. Updates on B-cell immunotherapies for systemic lupus erythematosus and Sjogren's syndrome. Current Opinion in Rheumatology. 24: 451-6. PMID 22871954 DOI: 10.1097/Bor.0B013E32835707E4  0.516
2012 Moshkani S, Kuzin II, Adewale F, Jansson J, Sanz I, Schwarz EM, Bottaro A. CD23+ CD21(high) CD1d(high) B cells in inflamed lymph nodes are a locally differentiated population with increased antigen capture and activation potential. Journal of Immunology (Baltimore, Md. : 1950). 188: 5944-53. PMID 22593620 DOI: 10.4049/Jimmunol.1103071  0.56
2012 Ramos-Casals M, Sanz I, Bosch X, Stone JH, Khamashta MA. B-cell-depleting therapy in systemic lupus erythematosus. The American Journal of Medicine. 125: 327-36. PMID 22444096 DOI: 10.1016/J.Amjmed.2011.09.010  0.523
2012 Barr PM, Wei C, Roger J, Schaefer-Cutillo J, Kelly JL, Rosenberg AF, Jung J, Sanz I, Friedberg JW. Syk inhibition with fostamatinib leads to transitional B lymphocyte depletion. Clinical Immunology (Orlando, Fla.). 142: 237-42. PMID 22284392 DOI: 10.1016/J.Clim.2011.12.012  0.646
2011 Hilchey SP, Rosenberg AF, Hyrien O, Secor-Socha S, Cochran MR, Brady MT, Wang JC, Sanz I, Burack WR, Quataert SA, Bernstein SH. Follicular lymphoma tumor-infiltrating T-helper (T(H)) cells have the same polyfunctional potential as normal nodal T(H) cells despite skewed differentiation. Blood. 118: 3591-602. PMID 21821704 DOI: 10.1182/Blood-2011-03-340646  0.408
2011 Wei C, Jung J, Sanz I. OMIP-003: phenotypic analysis of human memory B cells. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 894-6. PMID 21796774 DOI: 10.1002/Cyto.A.21112  0.517
2011 Sanz I. Connective tissue diseases: targeting B cells in SLE: good news at last! Nature Reviews. Rheumatology. 7: 255-6. PMID 21532638 DOI: 10.1038/Nrrheum.2011.48  0.533
2011 Lee FE, Halliley JL, Walsh EE, Moscatiello AP, Kmush BL, Falsey AR, Randall TD, Kaminiski DA, Miller RK, Sanz I. Circulating human antibody-secreting cells during vaccinations and respiratory viral infections are characterized by high specificity and lack of bystander effect. Journal of Immunology (Baltimore, Md. : 1950). 186: 5514-21. PMID 21441455 DOI: 10.4049/Jimmunol.1002932  0.403
2011 Quách TD, Manjarrez-Orduño N, Adlowitz DG, Silver L, Yang H, Wei C, Milner EC, Sanz I. Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM. Journal of Immunology (Baltimore, Md. : 1950). 186: 4640-8. PMID 21398610 DOI: 10.4049/Jimmunol.1001946  0.761
2010 Calero I, Sanz I. Targeting B cells for the treatment of SLE: the beginning of the end or the end of the beginning? Discovery Medicine. 10: 416-24. PMID 21122473  0.539
2010 Qian Y, Wei C, Eun-Hyung Lee F, Campbell J, Halliley J, Lee JA, Cai J, Kong YM, Sadat E, Thomson E, Dunn P, Seegmiller AC, Karandikar NJ, Tipton CM, Mosmann T, ... Sanz I, et al. Elucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry data. Cytometry. Part B, Clinical Cytometry. 78: S69-82. PMID 20839340 DOI: 10.1002/Cyto.B.20554  0.443
2010 Sanz I, Lee FE. B cells as therapeutic targets in SLE. Nature Reviews. Rheumatology. 6: 326-37. PMID 20520647 DOI: 10.1038/Nrrheum.2010.68  0.676
2010 Calero I, Nieto JA, Sanz I. B cell therapies for rheumatoid arthritis: beyond B cell depletion. Rheumatic Diseases Clinics of North America. 36: 325-43. PMID 20510237 DOI: 10.1016/J.Rdc.2010.02.003  0.666
2010 Li J, Kuzin I, Moshkani S, Proulx ST, Xing L, Skrombolas D, Dunn R, Sanz I, Schwarz EM, Bottaro A. Expanded CD23+/CD21hi B cells in inflamed lymph nodes are associated with the onset of inflammatory-erosive arthritis in TNF-transgenic mice and are targets of anti-CD20 therapy Journal of Immunology. 184: 6142-6150. PMID 20435928 DOI: 10.4049/Jimmunol.0903489  0.532
2010 Jacobi AM, Huang W, Wang T, Freimuth W, Sanz I, Furie R, Mackay M, Aranow C, Diamond B, Davidson A. Effect of long-term belimumab treatment on B cells in systemic lupus erythematosus: extension of a phase II, double-blind, placebo-controlled, dose-ranging study. Arthritis and Rheumatism. 62: 201-10. PMID 20039404 DOI: 10.1002/Art.27189  0.397
2010 Looney RJ, Anolik J, Sanz I. A perspective on B-cell-targeting therapy for SLE. Modern Rheumatology / the Japan Rheumatism Association. 20: 1-10. PMID 19669389 DOI: 10.1007/S10165-009-0213-X  0.464
2009 Sanz I. Indications of rituximab in autoimmune diseases. Drug Discovery Today. Therapeutic Strategies. 6: 13-19. PMID 20379381 DOI: 10.1016/J.Ddstr.2009.10.001  0.581
2009 Vinuesa CG, Sanz I, Cook MC. Dysregulation of germinal centres in autoimmune disease. Nature Reviews. Immunology. 9: 845-57. PMID 19935804 DOI: 10.1038/Nri2637  0.679
2009 Sanz I. Connective tissue diseases: The conundrum of B cell depletion in SLE. Nature Reviews. Rheumatology. 5: 304-5. PMID 19491910 DOI: 10.1038/Nrrheum.2009.100  0.638
2009 Palanichamy A, Barnard J, Zheng B, Owen T, Quach T, Wei C, Looney RJ, Sanz I, Anolik JH. Novel human transitional B cell populations revealed by B cell depletion therapy. Journal of Immunology (Baltimore, Md. : 1950). 182: 5982-93. PMID 19414749 DOI: 10.4049/jimmunol.0801859  0.757
2009 Anolik JH, Looney RJ, Lund FE, Randall TD, Sanz I. Insights into the heterogeneity of human B cells: diverse functions, roles in autoimmunity, and use as therapeutic targets. Immunologic Research. 45: 144-58. PMID 19350211 DOI: 10.1007/S12026-009-8096-7  0.674
2009 Crompton PD, Mircetic M, Weiss G, Baughman A, Huang CY, Topham DJ, Treanor JJ, Sanz I, Lee FE, Durbin AP, Miura K, Narum DL, Ellis RD, Malkin E, Mullen GE, et al. The TLR9 ligand CpG promotes the acquisition of Plasmodium falciparum-specific memory B cells in malaria-naive individuals. Journal of Immunology (Baltimore, Md. : 1950). 182: 3318-26. PMID 19234231 DOI: 10.4049/Jimmunol.0803596  0.359
2009 Manjarrez-Orduño N, Quách TD, Sanz I. B cells and immunological tolerance. The Journal of Investigative Dermatology. 129: 278-88. PMID 19148217 DOI: 10.1038/Jid.2008.240  0.767
2009 Jenks SA, Sanz I. Altered B cell receptor signaling in human systemic lupus erythematosus. Autoimmunity Reviews. 8: 209-13. PMID 18723129 DOI: 10.1016/J.Autrev.2008.07.047  0.614
2008 Sanz I, Wei C, Lee FE, Anolik J. Phenotypic and functional heterogeneity of human memory B cells. Seminars in Immunology. 20: 67-82. PMID 18258454 DOI: 10.1016/J.Smim.2007.12.006  0.625
2008 Anolik JH, Ravikumar R, Barnard J, Owen T, Almudevar A, Milner EC, Miller CH, Dutcher PO, Hadley JA, Sanz I. Cutting edge: anti-tumor necrosis factor therapy in rheumatoid arthritis inhibits memory B lymphocytes via effects on lymphoid germinal centers and follicular dendritic cell networks. Journal of Immunology (Baltimore, Md. : 1950). 180: 688-92. PMID 18178805 DOI: 10.4049/Jimmunol.180.2.688  0.493
2007 Anolik JH, Barnard J, Owen T, Zheng B, Kemshetti S, Looney RJ, Sanz I. Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. Arthritis and Rheumatism. 56: 3044-56. PMID 17763423 DOI: 10.1002/Art.22810  0.658
2007 Wei C, Anolik J, Cappione A, Zheng B, Pugh-Bernard A, Brooks J, Lee EH, Milner EC, Sanz I. A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 178: 6624-33. PMID 17475894 DOI: 10.4049/Jimmunol.178.10.6624  0.579
2007 Sanz I, Anolik JH, Looney RJ. B cell depletion therapy in autoimmune diseases. Frontiers in Bioscience : a Journal and Virtual Library. 12: 2546-67. PMID 17127262 DOI: 10.2741/2254  0.577
2007 Anolik JH, Friedberg JW, Zheng B, Barnard J, Owen T, Cushing E, Kelly J, Milner EC, Fisher RI, Sanz I. B cell reconstitution after rituximab treatment of lymphoma recapitulates B cell ontogeny. Clinical Immunology (Orlando, Fla.). 122: 139-45. PMID 17008130 DOI: 10.1016/J.Clim.2006.08.009  0.631
2006 Looney RJ, Anolik J, Sanz I. New therapies for systemic lupus erythematosus: cellular targets. Rheumatic Diseases Clinics of North America. 32: 201-15, xi. PMID 16504831 DOI: 10.1016/J.Rdc.2005.09.007  0.568
2005 Cappione A, Anolik JH, Pugh-Bernard A, Barnard J, Dutcher P, Silverman G, Sanz I. Germinal center exclusion of autoreactive B cells is defective in human systemic lupus erythematosus. The Journal of Clinical Investigation. 115: 3205-16. PMID 16211091 DOI: 10.1172/Jci24179  0.683
2005 Sanz I, Anolik J. Reconstitution of the adult B cell repertoire after treatment with rituximab. Arthritis Research & Therapy. 7: 175-6. PMID 16207341 DOI: 10.1186/Ar1799  0.662
2005 Milner EC, Anolik J, Cappione A, Sanz I. Human innate B cells: a link between host defense and autoimmunity? Springer Seminars in Immunopathology. 26: 433-52. PMID 15633016 DOI: 10.1007/S00281-004-0188-9  0.617
2005 Looney RJ, Anolik J, Sanz I. Treatment of SLE with anti-CD20 monoclonal antibody. Current Directions in Autoimmunity. 8: 193-205. PMID 15564722 DOI: 10.1159/000082104  0.624
2004 Anolik JH, Barnard J, Cappione A, Pugh-Bernard AE, Felgar RE, Looney RJ, Sanz I. Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosus. Arthritis and Rheumatism. 50: 3580-90. PMID 15529346 DOI: 10.1002/Art.20592  0.63
2004 Looney RJ, Anolik JH, Campbell D, Felgar RE, Young F, Arend LJ, Sloand JA, Rosenblatt J, Sanz I. B cell depletion as a novel treatment for systemic lupus erythematosus: a phase I/II dose-escalation trial of rituximab. Arthritis and Rheumatism. 50: 2580-9. PMID 15334472 DOI: 10.1002/Art.20430  0.56
2004 Anolik J, Sanz I. B cells in human and murine systemic lupus erythematosus. Current Opinion in Rheumatology. 16: 505-12. PMID 15314486 DOI: 10.1097/01.Bor.0000133660.52599.F6  0.589
2004 Looney RJ, Anolik J, Sanz I. B cells as therapeutic targets for rheumatic diseases. Current Opinion in Rheumatology. 16: 180-5. PMID 15103242 DOI: 10.1097/00002281-200405000-00003  0.596
2004 Cappione AJ, Pugh-Bernard AE, Anolik JH, Sanz I. Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 172: 4298-307. PMID 15034044 DOI: 10.4049/Jimmunol.172.7.4298  0.637
2004 Anolik J, Cappione A, Sanz I. Systemic lupus erythematosus is characterized by faulty B-cell tolerance in the germinal centers Arthritis Research & Therapy. 6: 90-90. DOI: 10.1186/Ar1405  0.681
2003 Anolik J, Sanz I, Looney RJ. B cell depletion therapy in systemic lupus erythematosus. Current Rheumatology Reports. 5: 350-6. PMID 12967516 DOI: 10.1007/S11926-003-0020-X  0.699
2003 Anolik J, Looney RJ, Bottaro A, Sanz I, Young F. Down-regulation of CD20 on B cells upon CD40 activation. European Journal of Immunology. 33: 2398-409. PMID 12938216 DOI: 10.1002/Eji.200323515  0.417
2003 Anolik JH, Campbell D, Felgar RE, Young F, Sanz I, Rosenblatt J, Looney RJ. The relationship of FcgammaRIIIa genotype to degree of B cell depletion by rituximab in the treatment of systemic lupus erythematosus. Arthritis and Rheumatism. 48: 455-9. PMID 12571855 DOI: 10.1002/Art.10764  0.683
2001 Pugh-Bernard AE, Silverman GJ, Cappione AJ, Villano ME, Ryan DH, Insel RA, Sanz I. Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance. The Journal of Clinical Investigation. 108: 1061-70. PMID 11581307 DOI: 10.1172/Jci12462  0.689
2001 del Rincon I, Zeidel M, Rey E, Harley JB, James JA, Fischbach M, Sanz I. Delineation of the human systemic lupus erythematosus anti-Smith antibody response using phage-display combinatorial libraries. Journal of Immunology (Baltimore, Md. : 1950). 165: 7011-6. PMID 11120828 DOI: 10.4049/Jimmunol.165.12.7011  0.606
2000 Rey E, Zeidel M, Rhine C, Tami J, Krolick K, Fischbach M, Sanz I. Characterization of human anti-acetylcholine receptor monoclonal autoantibodies from the peripheral blood of a myasthenia gravis patient using combinatorial libraries. Clinical Immunology (Orlando, Fla.). 96: 269-79. PMID 10964546 DOI: 10.1006/Clim.2000.4898  0.342
2000 Deng SX, Hanson E, Sanz I. In vivo cell penetration and intracellular transport of anti-Sm and anti-La autoantibodies. International Immunology. 12: 415-23. PMID 10744642 DOI: 10.1093/Intimm/12.4.415  0.665
1997 Raaphorst FM, Raman CS, Tami J, Fischbach M, Sanz I. Human Ig heavy chain CDR3 regions in adult bone marrow pre-B cells display an adult phenotype of diversity: evidence for structural selection of DH amino acid sequences. International Immunology. 9: 1503-15. PMID 9352355 DOI: 10.1093/Intimm/9.10.1503  0.532
1993 Dang H, Lazaridis K, Talal N, Fischbach M, Sanz I. Cloning of a Human IgM Autoantibody Bearing a Cross-Reactive Idiotype in a λ. Expression Vector: A New Approach to Studying Autoantibodies Clinical Immunology and Immunopathology. 67: 249-256. PMID 8500272 DOI: 10.1006/clin.1993.1072  0.432
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