| Year |
Citation |
Score |
| 2023 |
Ginzburg Y, An X, Rivella S, Goldfarb A. Normal and dysregulated crosstalk between iron metabolism and erythropoiesis. Elife. 12. PMID 37578340 DOI: 10.7554/eLife.90189 |
0.485 |
|
| 2022 |
Elagib KE, Brock A, Clementelli CM, Mosoyan G, Delehanty LL, Sahu RK, Pacheco-Benichou A, Fruit C, Besson T, Morris SW, Eto K, Jobaliya C, French DL, Gadue P, Singh S, ... ... Goldfarb AN, et al. Relieving Dyrk1a repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes. The Journal of Clinical Investigation. PMID 35925681 DOI: 10.1172/JCI154839 |
0.327 |
|
| 2022 |
White Z, Elagib KE, Gru AA, Goldfarb AN. Liver kinase B1 (LKB1) in murine erythroid progenitors modulates erythropoietin setpoint in association with maturation control. Blood Cells, Molecules & Diseases. 97: 102688. PMID 35717902 DOI: 10.1016/j.bcmd.2022.102688 |
0.378 |
|
| 2021 |
Goldfarb AN, Freeman KC, Sahu RK, Elagib KE, Holy M, Arneja A, Polanowska-Grabowska R, Gru AA, White Z, Khalil S, Kerins MJ, Ooi A, Leitinger N, Luckey CJ, Delehanty LL. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nature Communications. 12: 1645. PMID 33712594 DOI: 10.1038/s41467-021-21938-2 |
0.471 |
|
| 2019 |
Balogh P, Adelman ER, Pluvinage JV, Capaldo BJ, Freeman KC, Singh S, Elagib KE, Nakamura Y, Kurita R, Sashida G, Zunder ER, Li H, Gru AA, Price EA, Schrier SL, ... ... Goldfarb AN, et al. RUNX3 levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance. Haematologica. PMID 31171641 DOI: 10.3324/Haematol.2018.208918 |
0.386 |
|
| 2019 |
Goldfarb AN, Freeman K, Gru AA, White Z, Delehanty LL. Exploitation of a Newly Characterized Metabolic-Cytoskeletal Axis for Effective Combination Therapy of Iron Restricted Anemia Blood. 134: 2233-2233. DOI: 10.1182/Blood-2019-129172 |
0.587 |
|
| 2019 |
Elagib KE, Brock A, Mosoyan G, Clementelli C, Delehanty LL, Pacheco-Benichou A, Fruit C, Besson T, Morris S, Eto K, Iancu-Rubin C, Goldfarb AN. Harnessing a Novel Dyrk1a-Ablim2-MKL1 Regulatory Module in Megakaryocyte Morphogenesis to Enable Scalable Platelet "Pharming" Blood. 134: 3250-3250. DOI: 10.1182/Blood-2019-129049 |
0.458 |
|
| 2018 |
Balogh P, Capaldo B, Singh S, Elagib K, Li H, Zunder E, Figueroa ME, Pang W, Goldfarb A. Dysregulation of RUNX3 in Aged Human HSPCs May Contribute to Perturbations in Erythropoiesis and Balanced Lineage Output Blood. 132: 2553-2553. DOI: 10.1182/Blood-2018-99-115245 |
0.471 |
|
| 2017 |
Khalil S, Holy M, Grado S, Fleming R, Kurita R, Nakamura Y, Goldfarb A. A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2. Blood Advances. 1: 1181-1194. PMID 29296759 DOI: 10.1182/Bloodadvances.2016003772 |
0.565 |
|
| 2017 |
Khalil S, Delehanty L, Grado S, Holy M, White Z, Freeman K, Kurita R, Nakamura Y, Bullock G, Goldfarb A. Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor. The Journal of Experimental Medicine. PMID 29282252 DOI: 10.1084/Jem.20170396 |
0.538 |
|
| 2017 |
Elagib KE, Lu CH, Mosoyan G, Khalil S, Zasadzińska E, Foltz DR, Balogh P, Gru AA, Fuchs DA, Rimsza LM, Verhoeyen E, Sansó M, Fisher RP, Iancu-Rubin C, Goldfarb AN. Neonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition. The Journal of Clinical Investigation. PMID 28481226 DOI: 10.1172/Jci88936 |
0.382 |
|
| 2017 |
Balogh P, Goldfarb A. RUNX3 is required for megakaryocyte-erythroid specification in primary human progenitors Experimental Hematology. 53: S130. DOI: 10.1016/J.Exphem.2017.06.328 |
0.333 |
|
| 2016 |
Elagib KE, Lu C, Mosoyan G, Zasadzińska E, Foltz DR, Balogh P, Verhoeyen E, Sansó M, Fisher RP, Iancu-Rubin C, Goldfarb AN. An IGF2BP3-Cdk9 Pathway Governs the Human Fetal-Adult Megakaryocyte Transition Blood. 128: 886-886. DOI: 10.1182/Blood.V128.22.886.886 |
0.43 |
|
| 2016 |
Khalil S, Delehanty LL, Holy M, Grado S, Bullock GC, Goldfarb A. Regulation of the Erythroid Iron Deprivation Response By a TfR2-Scribble-Epor Integrated Module Coupling Iron Sensing with Receptor Presentation Blood. 128: 3615-3615. DOI: 10.1182/Blood.V128.22.3615.3615 |
0.576 |
|
| 2014 |
Elagib KE, Goldfarb AN. Megakaryocytic irreversible P-TEFb activation. Cell Cycle (Georgetown, Tex.). 13: 1827-8. PMID 24866976 DOI: 10.4161/Cc.29324 |
0.475 |
|
| 2014 |
Elagib KE, Lu C, Zasadzińska E, Foltz DR, Balogh P, Goldfarb AN. The Distinctive Morphogenesis of Infantile Megakaryopoiesis Is Associated with Altered P-TEFb Regulation By the Oncofetal Factor IGF2BP3 Blood. 124: 2911-2911. DOI: 10.1182/Blood.V124.21.2911.2911 |
0.479 |
|
| 2013 |
Elagib KE, Rubinstein JD, Delehanty LL, Ngoh VS, Greer PA, Li S, Lee JK, Li Z, Orkin SH, Mihaylov IS, Goldfarb AN. Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutation. Developmental Cell. 27: 607-20. PMID 24369834 DOI: 10.1016/J.Devcel.2013.11.013 |
0.722 |
|
| 2013 |
Richardson CL, Delehanty LL, Bullock GC, Rival CM, Tung KS, Kimpel DL, Gardenghi S, Rivella S, Goldfarb AN. Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response. The Journal of Clinical Investigation. 123: 3614-23. PMID 23863711 DOI: 10.1172/Jci68487 |
0.574 |
|
| 2012 |
Delehanty LL, Bullock GC, Goldfarb AN. Protein kinase D-HDAC5 signaling regulates erythropoiesis and contributes to erythropoietin cross-talk with GATA1. Blood. 120: 4219-28. PMID 22983445 DOI: 10.1182/Blood-2011-10-387050 |
0.495 |
|
| 2012 |
Rubinstein JD, Elagib KE, Goldfarb AN. Cyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis. The Journal of Biological Chemistry. 287: 19207-15. PMID 22514271 DOI: 10.1074/Jbc.M112.366476 |
0.758 |
|
| 2012 |
Richardson C, Delehanty LL, Goldfarb A. Iron Restriction Via PKC Signaling Critically Contributes to Erythroid PU.1 Dysregulation in Anemia of Chronic Inflammation Blood. 120: 3451-3451. DOI: 10.1182/Blood.V120.21.3451.3451 |
0.629 |
|
| 2011 |
Talbot AL, Bullock GC, Delehanty LL, Sattler M, Zhao ZJ, Goldfarb AN. Aconitase regulation of erythropoiesis correlates with a novel licensing function in erythropoietin-induced ERK signaling. Plos One. 6: e23850. PMID 21887333 DOI: 10.1371/Journal.Pone.0023850 |
0.796 |
|
| 2011 |
Rubinstein J, Elagib K, Goldfarb A. Cyclic AMP Signaling Inhibits Megakaryopoiesis by Targeting An E2A-CDKN1A Transcriptional Axis Blood. 118: 915-915. DOI: 10.1182/Blood.V118.21.915.915 |
0.757 |
|
| 2011 |
Elagib K, Rubinstein JD, Delehanty LL, Greer PA, Li S, Lee JK, Mihaylov IS, Li Z, Orkin SH, Goldfarb A. Calpain Drives Megakaryopoiesis by Targeting the 7SK snRNP Complex: A Connection to Down Syndrome Megakaryocytic Neoplasia Blood. 118: 552-552. DOI: 10.1182/Blood.V118.21.552.552 |
0.742 |
|
| 2011 |
Richardson CL, Bullock GC, Delehanty LL, Rival C, Tung K, Goldfarb A. Manipulating the Erythroid Iron Deprivation Response Affects Inflammatory Signaling in Anemia of Chronic Inflammation Blood. 118: 179-179. DOI: 10.1182/Blood.V118.21.179.179 |
0.597 |
|
| 2011 |
Bullock GC, Delehanty LL, Talbot AA, Richardson C, Goldfarb A. The Role of the Distal Erythropoietin Receptor in Iron Deficiency Anemia Blood. 118: 1312-1312. DOI: 10.1182/Blood.V118.21.1312.1312 |
0.592 |
|
| 2010 |
Goldfarb AN. Coordinating red cell differentiation with cell cycle arrest: GATA-1 activation of p21. Cell Cycle (Georgetown, Tex.). 9: 2061. PMID 20559028 DOI: 10.4161/Cc.9.11.11857 |
0.384 |
|
| 2010 |
Bullock GC, Delehanty LL, Talbot AL, Gonias SL, Tong WH, Rouault TA, Dewar B, Macdonald JM, Chruma JJ, Goldfarb AN. Iron control of erythroid development by a novel aconitase-associated regulatory pathway. Blood. 116: 97-108. PMID 20407036 DOI: 10.1182/Blood-2009-10-251496 |
0.805 |
|
| 2010 |
Delehanty LL, Goldfarb AN. Erythropoietin Regulates GATA-1 Function and Erythroid Differentiation by a PKD-HDAC5 Signal Transduction Pathway Blood. 116: 85-85. DOI: 10.1182/Blood.V116.21.85.85 |
0.561 |
|
| 2010 |
Rubinstein JD, Elagib K, Delehanty LL, Goldfarb AN. A Role for ETO-2 In Megakaryocytic Inhibition by Cyclic AMP Agonists Blood. 116: 289-289. DOI: 10.1182/Blood.V116.21.289.289 |
0.761 |
|
| 2010 |
Richardson CL, Bullock GC, Delehanty LL, Goldfarb AN. Targeting the Erythroid Iron Deprivation Response as a Therapeutic Approach In Anemia Not Caused by Iron Deficiency Blood. 116: 166-166. DOI: 10.1182/Blood.V116.21.166.166 |
0.568 |
|
| 2010 |
Talbot A, Bullock GC, Delehanty L, Goldfarb A. RSK Inhibition Rescues Defective Erythropoiesis Caused by Blockade of Mitochondrial Aconitase Blood. 116: 1008-1008. DOI: 10.1182/Blood.V116.21.1008.1008 |
0.79 |
|
| 2009 |
Goldfarb AN. Megakaryocytic programming by a transcriptional regulatory loop: A circle connecting RUNX1, GATA-1, and P-TEFb. Journal of Cellular Biochemistry. 107: 377-82. PMID 19350569 DOI: 10.1002/Jcb.22142 |
0.474 |
|
| 2009 |
Yeh JR, Munson KM, Elagib KE, Goldfarb AN, Sweetser DA, Peterson RT. Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. Nature Chemical Biology. 5: 236-43. PMID 19172146 DOI: 10.1038/Nchembio.147 |
0.407 |
|
| 2009 |
Talbot A, Bullock GC, Delehanty LL, Goldfarb A. Aconitase Modulates Erythroid Signaling through a Novel MEK-ERK Regulatory Pathway. Blood. 114: 75-75. DOI: 10.1182/BLOOD.V114.22.75.75 |
0.481 |
|
| 2009 |
Bullock GC, Delehanty LL, Talbot A, Gonias S, Tong W, Rouault T, Chruma J, Goldfarb A. Iron and Isocitrate Calibrate Erythropoietin Responsiveness of Erythroid Progenitors Via Aconitase Tuning of Protein Kinase C Activity. Blood. 114: 627-627. DOI: 10.1182/Blood.V114.22.627.627 |
0.796 |
|
| 2009 |
Elagib KE, Delehanty LL, Mihaylov I, Goldfarb A. Calpain Regulation of Megakaryopoiesis through a Positive Regulatory Loop Involving P-TEFb, GATA-1, and RUNX1. Blood. 114: 566-566. DOI: 10.1182/Blood.V114.22.566.566 |
0.473 |
|
| 2009 |
Richardson C, Bullock GC, Delehanty LL, Talbot A, Elagib KE, Rubinstein J, Goldfarb A. Synergy Between Specific Inflammatory Cytokines, IFNγ and TNFα, and Iron Restriction in Erythroid Blockade: A New Model for Anemia of Chronic Disease. Blood. 114: 159-159. DOI: 10.1182/blood.v114.22.159.159 |
0.795 |
|
| 2008 |
Elagib KE, Mihaylov IS, Delehanty LL, Bullock GC, Ouma KD, Caronia JF, Gonias SL, Goldfarb AN. Cross-talk of GATA-1 and P-TEFb in megakaryocyte differentiation. Blood. 112: 4884-94. PMID 18780834 DOI: 10.1182/Blood-2008-03-145722 |
0.424 |
|
| 2008 |
Elagib KE, Delehanty LL, Goldfarb A. A Murine Model for the Transient Myeloproliferative Disorder of Down Syndrome: Phenotypic Influence of p53 on Reversible Megakaryoblastic Disorder Blood. 112: 688-688. DOI: 10.1182/Blood.V112.11.688.688 |
0.397 |
|
| 2008 |
Bullock GC, Delehanty LL, Talbot A, Richardson C, Elagib KE, Goldfarb A. In Vitro and in Vivo Abrogation of An Erythroid Iron Restriction Developmental Checkpoint by Isocitrate through a Novel Erythropoietin- Coupled Signaling Mechanism Blood. 112: 417-417. DOI: 10.1182/Blood.V112.11.417.417 |
0.803 |
|
| 2008 |
Talbot A, Bullock GC, Delehanty LL, Gonias S, Goldfarb A. Stage-Restricted Non-Metabolic Function for Aconitase Enzymes in Erythropoietin Programming of Erythroid Growth and Differentiation in Vivo Blood. 112: 3865-3865. DOI: 10.1182/Blood.V112.11.3865.3865 |
0.795 |
|
| 2007 |
Elagib KE, Goldfarb AN. Regulation of RUNX1 transcriptional function by GATA-1. Critical Reviews in Eukaryotic Gene Expression. 17: 271-80. PMID 17725493 DOI: 10.1615/Critreveukargeneexpr.V17.I4.20 |
0.43 |
|
| 2007 |
Elagib KE, Goldfarb AN. Oncogenic pathways of AML1-ETO in acute myeloid leukemia: multifaceted manipulation of marrow maturation. Cancer Letters. 251: 179-86. PMID 17125917 DOI: 10.1016/J.Canlet.2006.10.010 |
0.411 |
|
| 2007 |
Bullock GC, Delehanty LL, Gonais SL, Goldfarb AN. Iron Control of Erythropoiesis: A Novel Pathway in Which Aconitase Enzymes Couple Metabolic Flux with Cellular Development. Blood. 110: 707-707. DOI: 10.1182/Blood.V110.11.707.707 |
0.61 |
|
| 2007 |
Elagib KE, Mihaylov IS, Delehanty LL, Bullock GC, Ouma KD, Caronia JF, Gonias SL, Goldfarb AN. Involvement of P-TEFb/CDK9 in Cooperative Transcriptional Activation of Megakaryocytic Genes by GATA-1 and RUNX1 and in Programming of Megakaryocytic Development In Vivo. Blood. 110: 1227-1227. DOI: 10.1182/Blood.V110.11.1227.1227 |
0.496 |
|
| 2006 |
Choi Y, Elagib KE, Delehanty LL, Goldfarb AN. Erythroid inhibition by the leukemic fusion AML1-ETO is associated with impaired acetylation of the major erythroid transcription factor GATA-1. Cancer Research. 66: 2990-6. PMID 16540647 DOI: 10.1158/0008-5472.Can-05-2944 |
0.455 |
|
| 2006 |
Goldfarb AN, Xiao M, Delehanty LL, Mihaylov IS. Erythroid-Specific Apoptosis Induced by Jun Transcription Factors Employs a Novel Pathway Involving Recruitment of COP1 and Itch Ubiquitin Ligases. Blood. 108: 80-80. DOI: 10.1182/Blood.V108.11.80.80 |
0.449 |
|
| 2006 |
Mihaylov IS, Elagib KE, Delehanty LL, Gonias SL, Caronia JF, Goldfarb AN. Orientation-Dependent Regulation of RUNX1 and GATA-1 Transcriptional Function by the p300/CBP Coactivators. Blood. 108: 1184-1184. DOI: 10.1182/Blood.V108.11.1184.1184 |
0.406 |
|
| 2006 |
Elagib KE, Mihaylov IS, Delehanty LL, Gonias SL, Caronia JF, Goldfarb AN. Regulation of RUNX1 Transcriptional Function by GATA-1 Kinase Recruitment: A Novel Pathway for Megakaryocytic Gene Regulation. Blood. 108: 1183-1183. DOI: 10.1182/Blood.V108.11.1183.1183 |
0.445 |
|
| 2005 |
Choi Y, Elagib KE, Goldfarb AN. AML-1-ETO-Mediated erythroid inhibition: new paradigms for differentiation blockade by a leukemic fusion protein. Critical Reviews in Eukaryotic Gene Expression. 15: 207-16. PMID 16390317 DOI: 10.1615/Critreveukargeneexpr.V15.I3.30 |
0.384 |
|
| 2005 |
Goldfarb AN. ERK expands its empire. Leukemia Research. 29: 1235-6. PMID 16098586 DOI: 10.1016/J.Leukres.2005.05.021 |
0.361 |
|
| 2004 |
Elagib KE, Xiao M, Hussaini IM, Delehanty LL, Palmer LA, Racke FK, Birrer MJ, Shanmugasundaram G, McDevitt MA, Goldfarb AN. Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2. Molecular and Cellular Biology. 24: 7779-94. PMID 15314183 DOI: 10.1128/Mcb.24.17.7779-7794.2004 |
0.443 |
|
| 2004 |
Choi Y, Elagib KE, Goldfarb AN. Erythroid Inhibition by AML1-ETO: Repression of GATA-1 Function by a Novel Non-Transcriptional Mechanism Involving Targeted Protein Degradation. Blood. 104: 388-388. DOI: 10.1182/Blood.V104.11.388.388 |
0.379 |
|
| 2003 |
Elagib KE, Racke FK, Mogass M, Khetawat R, Delehanty LL, Goldfarb AN. RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation. Blood. 101: 4333-41. PMID 12576332 DOI: 10.1182/Blood-2002-09-2708 |
0.469 |
|
| 2003 |
Delehanty LL, Mogass M, Gonias SL, Racke FK, Johnstone B, Goldfarb AN. Stromal inhibition of megakaryocytic differentiation is associated with blockade of sustained Rap1 activation. Blood. 101: 1744-51. PMID 12393469 DOI: 10.1182/Blood-2002-04-1278 |
0.503 |
|
| 2001 |
Goldfarb AN, Delehanty LL, Wang D, Racke FK, Hussaini IM. Stromal inhibition of megakaryocytic differentiation correlates with blockade of signaling by protein kinase C-epsilon and ERK/MAPK. The Journal of Biological Chemistry. 276: 29526-30. PMID 11395513 DOI: 10.1074/Jbc.M103825200 |
0.472 |
|
| 2001 |
Goldfarb AN, Wong D, Racke FK. Induction of megakaryocytic differentiation in primary human erythroblasts: a physiological basis for leukemic lineage plasticity. The American Journal of Pathology. 158: 1191-8. PMID 11290535 DOI: 10.1016/S0002-9440(10)64068-0 |
0.424 |
|
| 2001 |
Racke FK, Wang D, Zaidi Z, Kelley J, Visvader J, Soh JW, Goldfarb AN. A potential role for protein kinase C-epsilon in regulating megakaryocytic lineage commitment. The Journal of Biological Chemistry. 276: 522-8. PMID 11016926 DOI: 10.1074/jbc.M005236200 |
0.336 |
|
| 1997 |
Racke FK, Lewandowska K, Goueli S, Goldfarb AN. Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells. The Journal of Biological Chemistry. 272: 23366-70. PMID 9287350 DOI: 10.1074/jbc.272.37.23366 |
0.314 |
|
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