Barton Wicksteed - Publications

Affiliations: 
Molecular Metabolism and Nutrition University of Chicago, Chicago, IL 
Area:
Cell Biology, Nutrition

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Zapater JL, Wicksteed B, Layden BT. Enterocyte HKDC1 Modulates Intestinal Glucose Absorption in Male Mice Fed a High-fat Diet. Endocrinology. 163. PMID 35435980 DOI: 10.1210/endocr/bqac050  0.468
2020 Ilievski V, Toth PT, Valyi-Nagy K, Valyi-Nagy T, Green SJ, Marattil RS, Aljewari HW, Wicksteed B, O'Brien-Simpson NM, Reynolds EC, Layden BT, Unterman TG, Watanabe K. Identification of a periodontal pathogen and bihormonal cells in pancreatic islets of humans and a mouse model of periodontitis. Scientific Reports. 10: 9976. PMID 32561770 DOI: 10.1038/s41598-020-65828-x  0.437
2020 Priyadarshini M, Cole C, Oroskar G, Ludvik AE, Wicksteed B, He C, Layden BT. Free Fatty Acid Receptor 3 Differentially Contributes to Beta Cell Compensation Under High Fat Diet and Streptozotocin Stress. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 32073900 DOI: 10.1152/ajpregu.00128.2019  0.555
2018 Markussen LK, Winther S, Wicksteed B, Hansen JB. GSK3 is a negative regulator of the thermogenic program in brown adipocytes. Scientific Reports. 8: 3469. PMID 29472592 DOI: 10.1038/s41598-018-21795-y  0.429
2017 Yue J, Gou X, Li Y, Wicksteed B, Wu X. Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes. Cell Stem Cell. 21: 256-263.e4. PMID 28777946 DOI: 10.1016/J.Stem.2017.06.016  0.326
2016 Fuller M, Li X, Fisch R, Bughara M, Wicksteed B, Kovatcheva-Datchary P, Layden BT. FFA2 Contribution to Gestational Glucose Tolerance Is Not Disrupted by Antibiotics. Plos One. 11: e0167837. PMID 27959892 DOI: 10.1371/Journal.Pone.0167837  0.516
2016 Levine JA, Kaihara KA, Layden BT, Wicksteed B. Long-term activation of PKA in β-cells provides sustained improvement to glucose control, insulin sensitivity and body weight. Islets. 0. PMID 27340937 DOI: 10.1080/19382014.2016.1198457  0.79
2016 Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F. Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male. Cell Metabolism. PMID 27133133 DOI: 10.1016/J.Cmet.2016.03.015  0.696
2016 Dickson LM, Gandhi S, Layden BT, Cohen RN, Wicksteed B. Protein kinase A induces UCP1 expression in specific adipose depots to increase energy expenditure and improve metabolic health. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00114.2016. PMID 27097660 DOI: 10.1152/Ajpregu.00114.2016  0.416
2016 Priyadarshini M, Wicksteed B, Schiltz GE, Gilchrist A, Layden BT. SCFA Receptors in Pancreatic β Cells: Novel Diabetes Targets? Trends in Endocrinology and Metabolism: Tem. PMID 27091493 DOI: 10.1016/J.Tem.2016.03.011  0.496
2015 Priyadarshini M, Villa SR, Fuller M, Wicksteed B, Mackay CR, Alquier T, Poitout V, Mancebo H, Mirmira RG, Gilchrist A, Layden BT. An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion. Molecular Endocrinology (Baltimore, Md.). 29: 1055-66. PMID 26075576 DOI: 10.1210/Me.2015-1007  0.661
2015 Rajan S, Dickson LM, Mathew E, Orr CM, Ellenbroek JH, Philipson LH, Wicksteed B. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A. Molecular Metabolism. 4: 265-76. PMID 25830090 DOI: 10.1016/J.Molmet.2015.01.010  0.633
2015 Angueira AR, Ludvik AE, Reddy TE, Wicksteed B, Lowe WL, Layden BT. New insights into gestational glucose metabolism: lessons learned from 21st century approaches. Diabetes. 64: 327-34. PMID 25614666 DOI: 10.2337/Db14-0877  0.33
2015 Kaihara KA, Dickson LM, Ellenbroek JH, Orr CM, Layden BT, Wicksteed B. PKA Enhances the Acute Insulin Response Leading to the Restoration of Glucose Control. Diabetes. 64: 1688-97. PMID 25475437 DOI: 10.2337/Db14-1051  0.552
2013 Kaihara KA, Dickson LM, Jacobson DA, Tamarina N, Roe MW, Philipson LH, Wicksteed B. β-Cell-specific protein kinase A activation enhances the efficiency of glucose control by increasing acute-phase insulin secretion. Diabetes. 62: 1527-36. PMID 23349500 DOI: 10.2337/Db12-1013  0.784
2010 Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG, et al. Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain. Diabetes. 59: 3090-8. PMID 20802254 DOI: 10.2337/Db10-0624  0.392
2009 Jacobson DA, Wicksteed BL, Philipson LH. The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing. Diabetes. 58: 304-6. PMID 19171747 DOI: 10.2337/Db08-1618  0.43
2007 Uchizono Y, Alarcón C, Wicksteed BL, Marsh BJ, Rhodes CJ. The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead? Diabetes, Obesity & Metabolism. 9: 56-66. PMID 17919179 DOI: 10.1111/j.1463-1326.2007.00774.x  0.503
2007 Wicksteed B, Uchizono Y, Alarcon C, McCuaig JF, Shalev A, Rhodes CJ. A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation. Cell Metabolism. 5: 221-7. PMID 17339029 DOI: 10.1016/J.Cmet.2007.02.007  0.505
2006 Alarcon C, Wicksteed B, Rhodes CJ. Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level. Diabetologia. 49: 2920-9. PMID 17053883 DOI: 10.1007/s00125-006-0433-y  0.549
2006 Lingohr MK, Briaud I, Dickson LM, McCuaig JF, Alárcon C, Wicksteed BL, Rhodes CJ. Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet β-cells Journal of Biological Chemistry. 281: 15884-15892. PMID 16574657 DOI: 10.1074/jbc.M600356200  0.587
2005 Hays LB, Wicksteed B, Wang Y, McCuaig JF, Philipson LH, Edwardson JM, Rhodes CJ. Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic β-cells Journal of Endocrinology. 185: 57-67. PMID 15817827 DOI: 10.1677/joe.1.05934  0.643
2005 Pino MF, Ye DZ, Linning KD, Green CD, Wicksteed B, Poitout V, Olson LK. Elevated glucose attenuates human insulin gene promoter activity in INS-1 pancreatic beta-cells via reduced nuclear factor binding to the A5/core and Z element. Molecular Endocrinology (Baltimore, Md.). 19: 1343-60. PMID 15650027 DOI: 10.1210/Me.2003-0493  0.488
2003 Wicksteed B, Alarcon C, Briaud I, Lingohr MK, Rhodes CJ. Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin. The Journal of Biological Chemistry. 278: 42080-90. PMID 12928442 DOI: 10.1074/jbc.M303509200  0.492
2003 Kelpe CL, Moore PC, Parazzoli SD, Wicksteed B, Rhodes CJ, Poitout V. Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis. The Journal of Biological Chemistry. 278: 30015-21. PMID 12771145 DOI: 10.1074/Jbc.M302548200  0.555
2003 Yaekura K, Julyan R, Wicksteed BL, Hays LB, Alarcon C, Sommers S, Poitout V, Baskin DG, Wang Y, Philipson LH, Rhodes CJ. Insulin secretory deficiency and glucose intolerance in Rab3A null mice. The Journal of Biological Chemistry. 278: 9715-21. PMID 12510060 DOI: 10.1074/Jbc.M211352200  0.593
2002 Alarcon C, Wicksteed B, Prentki M, Corkey BE, Rhodes CJ. Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation. Diabetes. 51: 2496-504. PMID 12145163 DOI: 10.2337/Diabetes.51.8.2496  0.537
2001 Skelly RH, Wicksteed B, Antinozzi PA, Rhodes CJ. Glycerol-Stimulated Proinsulin Biosynthesis in Isolated Pancreatic Rat Islets via Adenoviral-Induced Expression of Glycerol Kinase Is Mediated via Mitochondrial Metabolism Diabetes. 50: 1791-1798. PMID 11473040 DOI: 10.2337/Diabetes.50.8.1791  0.56
1998 Skelly RH, Bollheimer LC, Wicksteed BL, Corkey BE, Rhodes CJ. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. The Biochemical Journal. 553-61. PMID 9531497 DOI: 10.1042/Bj3310553  0.452
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