Year |
Citation |
Score |
2021 |
Safaric Tepes P, Pal D, Lindsted T, Ibarra I, Lujambio A, Jimenez Sabinina V, Senturk S, Miller M, Korimerla N, Huang J, Glassman L, Lee P, Zeltsman D, Hyman K, Esposito M, ... ... Sordella R, et al. An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression. Elife. 10. PMID 34254585 DOI: 10.7554/eLife.66109 |
0.345 |
|
2017 |
Chen M, Nowak DG, Narula N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhut C, Wang VM, Wills L, ... ... Sordella R, et al. The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. The Journal of Cell Biology. PMID 28193700 DOI: 10.1083/Jcb.201604025 |
0.38 |
|
2016 |
Sordella R, Shirole NH, Pal D, Kastenhuber ER, Senturk S, Boroda J, Pisterzi P, Miller M, Munoz G, Anderluh M, Ladanyi M, Lowe SW. TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions. Elife. 5. PMID 27759562 DOI: 10.7554/Elife.17929 |
0.388 |
|
2016 |
Li J, Sordella R, Powers S. Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas. Scientific Reports. 6: 27891. PMID 27301828 DOI: 10.1038/Srep27891 |
0.44 |
|
2015 |
Nowak DG, Cho H, Herzka T, Watrud K, DeMarco DV, Wang VM, Senturk S, Fellmann C, Ding D, Beinortas T, Kleinman D, Chen M, Sordella R, Wilkinson JE, Castillo-Martin M, et al. MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discovery. 5: 636-51. PMID 25829425 DOI: 10.1158/2159-8290.Cd-14-1113 |
0.359 |
|
2014 |
Senturk S, Yao Z, Camiolo M, Stiles B, Rathod T, Walsh AM, Nemajerova A, Lazzara MJ, Altorki NK, Krainer A, Moll UM, Lowe SW, Cartegni L, Sordella R. p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proceedings of the National Academy of Sciences of the United States of America. 111: E3287-96. PMID 25074920 DOI: 10.1073/Pnas.1321640111 |
0.361 |
|
2014 |
Holembowski L, Kramer D, Riedel D, Sordella R, Nemajerova A, Dobbelstein M, Moll UM. TAp73 is essential for germ cell adhesion and maturation in testis. The Journal of Cell Biology. 204: 1173-90. PMID 24662569 DOI: 10.1083/Jcb.201306066 |
0.343 |
|
2014 |
Agrusa CJ, Sordella R, Paul S, Lee PC, Port J, Altorki NK, Stiles BM. A Novel Platform for Proteomic Analysis of Proximal Source Pulmonary Venous Blood Identifies Potential Biomarkers for Non-Small Cell Lung Cancer (NSCLC) Journal of the American College of Surgeons. 219. DOI: 10.1016/J.Jamcollsurg.2014.07.080 |
0.334 |
|
2014 |
Coppolino A, Agrusa CJ, Kajno E, Ryu S, Sordella R, Altorki NK, Stiles BM. Bone Marrow Induces STAT3 Pathway Activation in a Model of Disseminated Non-Small Cell Lung Cancer Cells Journal of the American College of Surgeons. 219. DOI: 10.1016/J.Jamcollsurg.2014.07.065 |
0.363 |
|
2013 |
Chaudhri VK, Salzler GG, Dick SA, Buckman MS, Sordella R, Karoly ED, Mohney R, Stiles BM, Elemento O, Altorki NK, McGraw TE. Metabolic alterations in lung cancer-associated fibroblasts correlated with increased glycolytic metabolism of the tumor. Molecular Cancer Research : McR. 11: 579-92. PMID 23475953 DOI: 10.1158/1541-7786.Mcr-12-0437-T |
0.348 |
|
2013 |
Abera M, Sordella R, Kazanietz M. Abstract 5261: PKC alpha is implicated in epithelial to mesenchymal transition and erlotinib resistance in non-small cell lung carcinoma cells. Cancer Research. 73: 5261-5261. DOI: 10.1158/1538-7445.Am2013-5261 |
0.386 |
|
2011 |
Premsrirut PK, Dow LE, Kim SY, Camiolo M, Malone CD, Miething C, Scuoppo C, Zuber J, Dickins RA, Kogan SC, Shroyer KR, Sordella R, Hannon GJ, Lowe SW. A rapid and scalable system for studying gene function in mice using conditional RNA interference Cell. 145: 145-158. PMID 21458673 DOI: 10.1016/J.Cell.2011.03.012 |
0.337 |
|
2010 |
Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, ... Sordella R, et al. Towards patient-based cancer therapeutics. Nature Biotechnology. 28: 904-6. PMID 20829823 DOI: 10.1038/Nbt0910-904 |
0.345 |
|
2010 |
Yao Z, Fenoglio S, Gao DC, Camiolo M, Stiles B, Lindsted T, Schlederer M, Johns C, Altorki N, Mittal V, Kenner L, Sordella R. TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 107: 15535-40. PMID 20713723 DOI: 10.1073/Pnas.1009472107 |
0.421 |
|
2008 |
Bell DW, Brannigan BW, Matsuo K, Finkelstein DM, Sordella R, Settleman J, Mitsudomi T, Haber DA. Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 4079-84. PMID 18593984 DOI: 10.1158/1078-0432.Ccr-07-5030 |
0.372 |
|
2008 |
Xue W, Krasnitz A, Lucito R, Sordella R, Vanaelst L, Cordon-Cardo C, Singer S, Kuehnel F, Wigler M, Powers S, Zender L, Lowe SW. DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes & Development. 22: 1439-44. PMID 18519636 DOI: 10.1101/Gad.1672608 |
0.366 |
|
2007 |
Mulloy R, Ferrand A, Kim Y, Sordella R, Bell DW, Haber DA, Anderson KS, Settleman J. Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib Cancer Research. 67: 2325-2330. PMID 17332364 DOI: 10.1158/0008-5472.Can-06-4293 |
0.412 |
|
2006 |
Haber DA, Bell DW, Sordella R, Kwak EL, Godin-Heymann N, Sharma SV, Lynch TJ, Settleman J. Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors. Cold Spring Harbor Symposia On Quantitative Biology. 70: 419-26. PMID 16869779 DOI: 10.1101/Sqb.2005.70.043 |
0.411 |
|
2006 |
Smolen GA, Sordella R, Muir B, Mohapatra G, Barmettler A, Archibald H, Kim WJ, Okimoto RA, Bell DW, Sgroi DC, Christensen JG, Settleman J, Haber DA. Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proceedings of the National Academy of Sciences of the United States of America. 103: 2316-21. PMID 16461907 DOI: 10.1073/Pnas.0508776103 |
0.415 |
|
2005 |
Bell DW, Gore I, Okimoto RA, Godin-Heymann N, Sordella R, Mulloy R, Sharma SV, Brannigan BW, Mohapatra G, Settleman J, Haber DA. Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nature Genetics. 37: 1315-6. PMID 16258541 DOI: 10.1038/Ng1671 |
0.411 |
|
2005 |
Barberis D, Casazza A, Sordella R, Corso S, Artigiani S, Settleman J, Comoglio PM, Tamagnone L. p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling Journal of Cell Science. 118: 4689-4700. PMID 16188938 DOI: 10.1242/Jcs.02590 |
0.379 |
|
2005 |
Kwak EL, Sordella R, Bell DW, Godin-Heymann N, Okimoto RA, Brannigan BW, Harris PL, Driscoll DR, Fidias P, Lynch TJ, Rabindran SK, McGinnis JP, Wissner A, Sharma SV, Isselbacher KJ, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proceedings of the National Academy of Sciences of the United States of America. 102: 7665-70. PMID 15897464 DOI: 10.1073/Pnas.0502860102 |
0.397 |
|
2005 |
Jiang W, Sordella R, Chen GC, Hakre S, Roy AL, Settleman J. An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression Molecular Cell. 17: 23-35. PMID 15629714 DOI: 10.1016/J.Molcel.2004.11.024 |
0.329 |
|
2004 |
Sordella R, Bell DW, Haber DA, Settleman J. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science (New York, N.Y.). 305: 1163-7. PMID 15284455 DOI: 10.1126/Science.1101637 |
0.424 |
|
2004 |
Kontaridis MI, Eminaga S, Fornaro M, Zito CI, Sordella R, Settleman J, Bennett AM. SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Molecular and Cellular Biology. 24: 5340-52. PMID 15169898 DOI: 10.1128/Mcb.24.12.5340-5352.2004 |
0.342 |
|
2004 |
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, Harris PL, Haserlat SM, Supko JG, Haluska FG, Louis DN, Christiani DC, Settleman J, Haber DA. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine. 350: 2129-39. PMID 15118073 DOI: 10.1056/Nejmoa040938 |
0.437 |
|
2003 |
Sordella R, Jiang W, Chen G, Curto M, Settleman J. Modulation of Rho GTPase Signaling Regulates a Switch between Adipogenesis and Myogenesis Cell. 113: 147-158. PMID 12705864 DOI: 10.1016/S0092-8674(03)00271-X |
0.353 |
|
2003 |
Yajnik V, Paulding C, Sordella R, McClatchey AI, Saito M, Wahrer DC, Reynolds P, Bell DW, Lake R, van den Heuvel S, Settleman J, Haber DA. DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell. 112: 673-84. PMID 12628187 DOI: 10.1016/S0092-8674(03)00155-7 |
0.406 |
|
2002 |
Sordella R, Classon M, Hu KQ, Matheson SF, Brouns MR, Fine B, Zhang L, Takami H, Yamada Y, Settleman J. Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development. Developmental Cell. 2: 553-65. PMID 12015964 DOI: 10.1016/S1534-5807(02)00162-4 |
0.338 |
|
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