Holger Willenbring - Publications

Affiliations: 
Biomedical Sciences University of California, San Francisco, San Francisco, CA 
Area:
Cell Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Laemmle A, Poms M, Hsu B, Borsuk M, Rüfenacht V, Robinson J, Sadowski MC, Nuoffer JM, Häberle J, Willenbring H. Aquaporin 9 Induction in Human iPSC-derived Hepatocytes Facilitates Modeling of Ornithine Transcarbamylase Deficiency. Hepatology (Baltimore, Md.). PMID 34786702 DOI: 10.1002/hep.32247  0.405
2021 Duwaerts CC, Le Guillou D, Her CL, Phillips NJ, Willenbring H, Mattis AN, Maher JJ. iPSC-derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile. Gastroenterology. PMID 33640436 DOI: 10.1053/j.gastro.2021.02.050  0.676
2020 Kurial SNT, Willenbring H. Transcriptomic traces of adult human liver progenitor cells. Hepatology (Baltimore, Md.). PMID 31991483 DOI: 10.1002/Hep.31143  0.569
2019 Chen F, Jimenez RJ, Sharma K, Luu HY, Hsu BY, Ravindranathan A, Stohr BA, Willenbring H. Broad Distribution of Hepatocyte Proliferation in Liver Homeostasis and Regeneration. Cell Stem Cell. PMID 31866223 DOI: 10.1016/J.Stem.2019.11.001  0.514
2019 Willenbring H, Colnot S. Decision letter: Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts Elife. DOI: 10.7554/Elife.46206.Sa1  0.361
2018 Huck I, Gunewardena S, Espanol-Suner R, Willenbring H, Apte U. Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration. Hepatology (Baltimore, Md.). PMID 30520062 DOI: 10.1002/Hep.30405  0.48
2018 Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. PMID 29720662 DOI: 10.1038/S41586-018-0075-5  0.735
2016 Rezvani M, Español-Suñer R, Malato Y, Dumont L, Grimm AA, Kienle E, Bindman JG, Wiedtke E, Hsu BY, Naqvi SJ, Schwabe RF, Corvera CU, Grimm D, Willenbring H. In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis. Cell Stem Cell. 18: 809-816. PMID 27257763 DOI: 10.1016/J.Stem.2016.05.005  0.555
2016 Rezvani M, Grimm AA, Willenbring H. Assessing the therapeutic potential of lab-made hepatocytes. Hepatology (Baltimore, Md.). 64: 287-94. PMID 27014802 DOI: 10.1002/Hep.28569  0.556
2016 Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT. Physiological Ranges of Matrix Rigidity Modulate Primary Mouse Hepatocyte Function In Part Through Hepatocyte Nuclear Factor 4 Alpha. Hepatology (Baltimore, Md.). PMID 26755329 DOI: 10.1002/Hep.28450  0.45
2015 Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology (Baltimore, Md.). 61: 141-52. PMID 25131933 DOI: 10.1002/Hep.27379  0.681
2014 Hentzschel F, Hammerschmidt-Kamper C, Börner K, Heiss K, Knapp B, Sattler JM, Kaderali L, Castoldi M, Bindman JG, Malato Y, Willenbring H, Mueller AK, Grimm D. AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2130-41. PMID 25189739 DOI: 10.1038/Mt.2014.172  0.472
2014 Schaub JR, Malato Y, Gormond C, Willenbring H. Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury. Cell Reports. 8: 933-9. PMID 25131204 DOI: 10.1016/J.Celrep.2014.07.003  0.549
2014 Espejel S, Eckardt S, Harbell J, Roll GR, McLaughlin KJ, Willenbring H. Brief report: Parthenogenetic embryonic stem cells are an effective cell source for therapeutic liver repopulation. Stem Cells (Dayton, Ohio). 32: 1983-8. PMID 24740448 DOI: 10.1002/Stem.1726  0.55
2014 Ng R, Wu H, Xiao H, Chen X, Willenbring H, Steer CJ, Song G. Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia. Hepatology (Baltimore, Md.). 60: 554-64. PMID 24677249 DOI: 10.1002/Hep.27153  0.626
2014 Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 508: 93-7. PMID 24572354 DOI: 10.1038/Nature13020  0.745
2014 Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, Song G, Riordan J, Anderton B, Cheung ST, Willenbring H, Dupuy A, Chen X, Brown D, Chang AN, et al. MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer. Hepatology (Baltimore, Md.). 59: 202-15. PMID 23913442 DOI: 10.1002/Hep.26662  0.602
2014 Schaub JR, Malato Y, Gormond C, Willenbring H. Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury Cell Reports. 8: 933-939. DOI: 10.1016/j.celrep.2014.07.003  0.392
2013 Mathur A, Loskill P, Hong S, Lee J, Marcus SG, Dumont L, Conklin BR, Willenbring H, Lee LP, Healy KE. Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development. Stem Cell Research & Therapy. 4: S14. PMID 24565415 DOI: 10.1186/Scrt375  0.383
2013 Willenbring H, Soto-Gutierrez A. Transplantable liver organoids made from only three ingredients. Cell Stem Cell. 13: 139-40. PMID 23910079 DOI: 10.1016/J.Stem.2013.07.014  0.547
2013 Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern MA. Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells. Stem Cells Translational Medicine. 2: 409-19. PMID 23681950 DOI: 10.5966/Sctm.2012-0160  0.467
2013 Willenbring H, Grompe M. A therapy for liver failure found in the JNK yard. Cell. 153: 283-4. PMID 23582318 DOI: 10.1016/J.Cell.2013.03.033  0.514
2013 Evert M, Fan B, Malato Y, Ribback S, Dombrowski F, Willenbring H, Chen X, Calvisi D. Akt/Notch activation drives rapid cholangiocarcinoma development originating from mature hepatocytes in the mouse Zeitschrift FüR Gastroenterologie. 51. DOI: 10.1055/S-0032-1332061  0.415
2012 Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, Gores GJ, Dombrowski F, Evert M, Chen X, Willenbring H. Cholangiocarcinomas can originate from hepatocytes in mice. The Journal of Clinical Investigation. 122: 2911-5. PMID 22797301 DOI: 10.1172/Jci63212  0.574
2012 Mattis AN, Willenbring H. A ZFN/piggyBac step closer to autologous liver cell therapy. Hepatology (Baltimore, Md.). 55: 2033-5. PMID 22422378 DOI: 10.1002/Hep.25715  0.711
2012 Ng R, Song G, Roll GR, Frandsen NM, Willenbring H. A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. The Journal of Clinical Investigation. 122: 1097-108. PMID 22326957 DOI: 10.1172/Jci46039  0.589
2012 Rountree CB, Mishra L, Willenbring H. Stem cells in liver diseases and cancer: recent advances on the path to new therapies. Hepatology (Baltimore, Md.). 55: 298-306. PMID 22030746 DOI: 10.1002/Hep.24762  0.549
2011 Malato Y, Naqvi S, Schürmann N, Ng R, Wang B, Zape J, Kay MA, Grimm D, Willenbring H. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. The Journal of Clinical Investigation. 121: 4850-60. PMID 22105172 DOI: 10.1172/Jci59261  0.685
2011 Willenbring H. A simple code for installing hepatocyte function. Cell Stem Cell. 9: 89-91. PMID 21816357 DOI: 10.1016/J.Stem.2011.07.009  0.339
2011 Eckardt S, McLaughlin KJ, Willenbring H. Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration. Cell Cycle (Georgetown, Tex.). 10: 2091-9. PMID 21606677 DOI: 10.4161/Cc.10.13.16360  0.375
2011 D'Alessio JA, Ng R, Willenbring H, Tjian R. Core promoter recognition complex changes accompany liver development. Proceedings of the National Academy of Sciences of the United States of America. 108: 3906-11. PMID 21368148 DOI: 10.1073/Pnas.1100640108  0.579
2010 Malato Y, Willenbring H. The MAP3K TAK1: a chock block to liver cancer formation. Hepatology (Baltimore, Md.). 52: 1506-9. PMID 20879030 DOI: 10.1002/hep.23878  0.327
2010 Roll GR, Willenbring H. Transplanted nonviable human hepatocytes produce appreciable serum albumin levels in mice. Stem Cell Research. 5: 267-70. PMID 20829142 DOI: 10.1016/J.Scr.2010.07.004  0.434
2010 Espejel S, Roll GR, McLaughlin KJ, Lee AY, Zhang JY, Laird DJ, Okita K, Yamanaka S, Willenbring H. Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. The Journal of Clinical Investigation. 120: 3120-6. PMID 20739754 DOI: 10.1172/Jci43267  0.55
2010 Erker L, Azuma H, Lee AY, Guo C, Orloff S, Eaton L, Benedetti E, Jensen B, Finegold M, Willenbring H, Grompe M. Therapeutic liver reconstitution with murine cells isolated long after death. Gastroenterology. 139: 1019-29. PMID 20621682 DOI: 10.1053/J.Gastro.2010.05.082  0.489
2010 Song G, Sharma AD, Roll GR, Ng R, Lee AY, Blelloch RH, Frandsen NM, Willenbring H. MicroRNAs control hepatocyte proliferation during liver regeneration. Hepatology (Baltimore, Md.). 51: 1735-43. PMID 20432256 DOI: 10.1002/Hep.23547  0.605
2008 Mitchell C, Willenbring H. A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice. Nature Protocols. 3: 1167-70. PMID 18600221 DOI: 10.1038/Nprot.2008.80  0.446
2008 Willenbring H, Sharma AD, Vogel A, Lee AY, Rothfuss A, Wang Z, Finegold M, Grompe M. Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis. Cancer Cell. 14: 59-67. PMID 18598944 DOI: 10.1016/J.Ccr.2008.05.004  0.388
2007 Ramalho-Santos M, Willenbring H. On the origin of the term "stem cell". Cell Stem Cell. 1: 35-8. PMID 18371332 DOI: 10.1016/J.Stem.2007.05.013  0.331
2006 Bailey AS, Willenbring H, Jiang S, Anderson DA, Schroeder DA, Wong MH, Grompe M, Fleming WH. Myeloid lineage progenitors give rise to vascular endothelium. Proceedings of the National Academy of Sciences of the United States of America. 103: 13156-61. PMID 16920790 DOI: 10.1073/Pnas.0604203103  0.322
2006 Rizvi AZ, Swain JR, Davies PS, Bailey AS, Decker AD, Willenbring H, Grompe M, Fleming WH, Wong MH. Bone marrow-derived cells fuse with normal and transformed intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 6321-5. PMID 16606845 DOI: 10.1073/Pnas.0508593103  0.373
2006 Vogel A, Aslan JE, Willenbring H, Klein C, Finegold M, Mount H, Thomas G, Grompe M. Sustained phosphorylation of Bid is a marker for resistance to Fas-induced apoptosis during chronic liver diseases. Gastroenterology. 130: 104-19. PMID 16401474 DOI: 10.1053/J.Gastro.2005.10.012  0.416
2006 Held PK, Al-Dhalimy M, Willenbring H, Akkari Y, Jiang S, Torimaru Y, Olson S, Fleming WH, Finegold M, Grompe M. In vivo genetic selection of renal proximal tubules. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 49-58. PMID 16216560 DOI: 10.1016/J.Ymthe.2005.09.004  0.405
2005 Bailey AS, Willenbring H, Jiang S, Schroeder DA, Anderson DA, Grompe M, Wong MH, Fleming WH. Myeloid Lineage-Restricted Progenitors Contribute to Vascular Endothelium. Blood. 106: 2267-2267. DOI: 10.1182/Blood.V106.11.2267.2267  0.384
2004 Willenbring H, Grompe M. Delineating the hepatocyte's hematopoietic fusion partner. Cell Cycle (Georgetown, Tex.). 3: 1489-91. PMID 15611666 DOI: 10.4161/Cc.3.12.1304  0.4
2004 Willenbring H, Bailey AS, Foster M, Akkari Y, Dorrell C, Olson S, Finegold M, Fleming WH, Grompe M. Myelomonocytic cells are sufficient for therapeutic cell fusion in liver. Nature Medicine. 10: 744-8. PMID 15195088 DOI: 10.1038/Nm1062  0.472
2003 Willenbring H, Grompe M. Embryonic versus adult stem cell pluripotency: in liver only fusion matters. Journal of Assisted Reproduction and Genetics. 20: 393-4. PMID 14649377 DOI: 10.1023/A:1026233224751  0.478
2003 Wang X, Willenbring H, Akkari Y, Torimaru Y, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Olson S, Grompe M. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature. 422: 897-901. PMID 12665832 DOI: 10.1038/Nature01531  0.459
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