| Year |
Citation |
Score |
| 2023 |
Halasz L, Divoux A, Sandor K, Erdos E, Daniel B, Smith SR, Osborne TF. An Atlas of Promoter Chromatin Modifications and HiChIP Regulatory Interactions in Human Subcutaneous Adipose-Derived Stem Cells. International Journal of Molecular Sciences. 25. PMID 38203607 DOI: 10.3390/ijms25010437 |
0.336 |
|
| 2023 |
Erdos E, Sandor K, Young-Erdos CL, Halasz L, Smith SR, Osborne TF, Divoux A. Transcriptional Control of Subcutaneous Adipose Tissue by the Transcription Factor CTCF Modulates Heterogeneity in Fat Distribution in Women. Cells. 13. PMID 38201289 DOI: 10.3390/cells13010086 |
0.402 |
|
| 2023 |
Wang T, Soundararajan A, Rabinowitz J, Jaiswal A, Osborne T, Pattabiraman PP. Identification of the novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 37: e23248. PMID 37823226 DOI: 10.1096/fj.202301185R |
0.438 |
|
| 2023 |
Wang T, Soundararajan A, Rabinowitz J, Jaiswal A, Osborne T, Pattabiraman PP. Identification of the novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation. Biorxiv : the Preprint Server For Biology. PMID 37214961 DOI: 10.1101/2023.02.05.527136 |
0.434 |
|
| 2022 |
Takahashi H, Yang G, Yoneshiro T, Abe Y, Ito R, Yang C, Nakazono J, Okamoto-Katsuyama M, Uchida A, Arai M, Jin H, Choi H, Tumenjargal M, Xie S, Zhang J, ... ... Osborne TF, et al. MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis. Nature Communications. 13: 5715. PMID 36175407 DOI: 10.1038/s41467-022-33363-0 |
0.342 |
|
| 2022 |
Lee JH, Lee SH, Lee EH, Cho JY, Song DK, Lee YJ, Kwon TK, Oh BC, Cho KW, Osborne TF, Jeon TI, Im SS. SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization. Journal of Advanced Research. PMID 35659922 DOI: 10.1016/j.jare.2022.05.013 |
0.323 |
|
| 2022 |
Erdos E, Divoux A, Sandor K, Halasz L, Smith SR, Osborne TF. Unique role for lncRNA HOTAIR in defining depot-specific gene expression patterns in human adipose-derived stem cells. Genes & Development. 36: 566-581. PMID 35618313 DOI: 10.1101/gad.349393.122 |
0.353 |
|
| 2021 |
Nguyen TTP, Kim DY, Lee YG, Lee YS, Truong XT, Lee JH, Song DK, Kwon TK, Park SH, Jung CH, Moon C, Osborne TF, Im SS, Jeon TI. SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice. Molecular Cell. PMID 34233158 DOI: 10.1016/j.molcel.2021.06.003 |
0.371 |
|
| 2021 |
Zhang J, Matsumura Y, Kano Y, Yoshida A, Kawamura T, Hirakawa H, Inagaki T, Tanaka T, Kimura H, Yanagi S, Fukami K, Doi T, Osborne TF, Kodama T, Aburatani H, et al. Ubiquitination dependent and independent repression of target genes by SETDB1 reveals a context dependent role for its methyltransferase activity during adipogenesis. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 33971063 DOI: 10.1111/gtc.12868 |
0.321 |
|
| 2020 |
Esquejo RM, Roqueta-Rivera M, Shao W, Phelan PE, Seneviratne U, Am Ende CW, Hershberger PM, Machamer CE, Espenshade PJ, Osborne TF. Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum. Cell Chemical Biology. PMID 33096051 DOI: 10.1016/j.chembiol.2020.10.003 |
0.434 |
|
| 2020 |
Lee JH, Go Y, Kim DY, Lee SH, Kim OH, Jeon YH, Kwon TK, Bae JH, Song DK, Rhyu IJ, Lee IK, Shong M, Oh BC, Petucci C, Park JW, ... Osborne TF, et al. Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue. Experimental & Molecular Medicine. PMID 32015410 DOI: 10.1038/S12276-020-0379-Z |
0.302 |
|
| 2019 |
Liebergall SR, Angdisen J, Chan SH, Chang Y, Osborne TF, Koeppel AF, Turner SD, Schulman IG. Inflammation triggers liver X receptor-dependent lipogenesis. Molecular and Cellular Biology. PMID 31658997 DOI: 10.1128/Mcb.00364-19 |
0.421 |
|
| 2019 |
Kim DK, Kim YH, Lee JH, Jung YS, Kim J, Feng R, Jeon TI, Lee IK, Cho SJ, Im SS, Dooley S, Osborne TF, Lee CH, Choi HS. Estrogen-related receptor γ controls sterol regulatory element-binding protein-1c expression and alcoholic fatty liver. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 158521. PMID 31479733 DOI: 10.1016/J.Bbalip.2019.158521 |
0.426 |
|
| 2019 |
Che L, Chi W, Qiao Y, Zhang J, Song X, Liu Y, Li L, Jia J, Pilo MG, Wang J, Cigliano A, Ma Z, Kuang W, Tang Z, Zhang Z, ... ... Osborne TF, et al. Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans. Gut. PMID 30954949 DOI: 10.1136/Gutjnl-2018-317581 |
0.315 |
|
| 2018 |
Lee JH, Phelan P, Shin M, Oh BC, Han X, Im SS, Osborne TF. SREBP-1a-stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1. Proceedings of the National Academy of Sciences of the United States of America. PMID 30530672 DOI: 10.1073/Pnas.1813458115 |
0.415 |
|
| 2018 |
Divoux A, Sandor K, Bojcsuk D, Talukder A, Li X, Balint BL, Osborne TF, Smith SR. Differential open chromatin profile and transcriptomic signature define depot-specific human subcutaneous preadipocytes: primary outcomes. Clinical Epigenetics. 10: 148. PMID 30477572 DOI: 10.1186/S13148-018-0582-0 |
0.38 |
|
| 2018 |
Smith K, Karimian-Azari E, LaMoia TE, Hussain T, Vargova V, Karolyi K, Veldhuis PP, Arnoletti JP, de la Fuente SG, Pratley RE, Osborne TF, Kyriazis GA. T1R2 receptor-mediated glucose sensing in the upper intestine potentiates glucose absorption through activation of local regulatory pathways. Molecular Metabolism. PMID 30201274 DOI: 10.1016/J.Molmet.2018.08.009 |
0.357 |
|
| 2018 |
Abe Y, Fujiwara Y, Takahashi H, Matsumura Y, Sawada T, Jiang S, Nakaki R, Uchida A, Nagao N, Naito M, Kajimura S, Kimura H, Osborne TF, Aburatani H, Kodama T, et al. Histone demethylase JMJD1A coordinates acute and chronic adaptation to cold stress via thermogenic phospho-switch. Nature Communications. 9: 1566. PMID 29674659 DOI: 10.1038/S41467-018-03868-8 |
0.335 |
|
| 2018 |
Esquejo RM, Salatto CT, Delmore J, Albuquerque B, Reyes A, Shi Y, Moccia R, Cokorinos E, Peloquin M, Monetti M, Barricklow J, Bollinger E, Smith BK, Day EA, Nguyen C, ... ... Osborne TF, et al. Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models. Ebiomedicine. PMID 29673898 DOI: 10.1016/J.Ebiom.2018.04.009 |
0.397 |
|
| 2017 |
Costford SR, Brouwers B, Hopf ME, Sparks LM, Dispagna M, Gomes AP, Cornnell HH, Petucci C, Phelan P, Xie H, Yi F, Walter GA, Osborne TF, Sinclair DA, Mynatt RL, et al. Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance. Molecular Metabolism. PMID 29146412 DOI: 10.1016/J.Molmet.2017.10.012 |
0.32 |
|
| 2017 |
Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS. Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis. Cell Reports. 19: 2116-2129. PMID 28591582 DOI: 10.1016/J.Celrep.2017.05.032 |
0.428 |
|
| 2016 |
Kim KY, Jang HJ, Yang YR, Park KI, Seo J, Shin IW, Jeon TI, Ahn SC, Suh PG, Osborne TF, Seo YK. SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy. Scientific Reports. 6: 35732. PMID 27767079 DOI: 10.1038/Srep35732 |
0.421 |
|
| 2016 |
Roqueta-Rivera M, Esquejo RM, Phelan PE, Sandor K, Daniel B, Foufelle F, Ding J, Li X, Khorasanizadeh S, Osborne TF. SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation. Cell Metabolism. PMID 27568546 DOI: 10.1016/J.Cmet.2016.07.025 |
0.532 |
|
| 2016 |
Jeon TI, Osborne TF. miRNA and cholesterol homeostasis. Biochimica Et Biophysica Acta. PMID 26778752 DOI: 10.1016/J.Bbalip.2016.01.005 |
0.388 |
|
| 2015 |
Vergnes L, Chin RG, de Aguiar Vallim T, Fong LG, Osborne TF, Young SG, Reue K. SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression. Journal of Lipid Research. PMID 26685326 DOI: 10.1194/Jlr.M064022 |
0.453 |
|
| 2015 |
Matsumura Y, Nakaki R, Inagaki T, Yoshida A, Kano Y, Kimura H, Tanaka T, Tsutsumi S, Nakao M, Doi T, Fukami K, Osborne TF, Kodama T, Aburatani H, Sakai J. H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation. Molecular Cell. 60: 584-96. PMID 26590716 DOI: 10.1016/J.Molcel.2015.10.025 |
0.436 |
|
| 2015 |
Abe Y, Rozqie R, Matsumura Y, Kawamura T, Nakaki R, Tsurutani Y, Tanimura-Inagaki K, Shiono A, Magoori K, Nakamura K, Ogi S, Kajimura S, Kimura H, Tanaka T, Fukami K, ... Osborne TF, et al. JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesis. Nature Communications. 6: 7052. PMID 25948511 DOI: 10.1038/Ncomms8052 |
0.421 |
|
| 2015 |
Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, Yamasaki A, Tsurutani Y, Yoshida A, Chikaoka Y, Nakamura K, Magoori K, Nakaki R, Osborne TF, Fukami K, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. The Journal of Biological Chemistry. 290: 4163-77. PMID 25533466 DOI: 10.1074/Jbc.M114.626929 |
0.442 |
|
| 2014 |
Masri S, Rigor P, Cervantes M, Ceglia N, Sebastian C, Xiao C, Roqueta-Rivera M, Deng C, Osborne TF, Mostoslavsky R, Baldi P, Sassone-Corsi P. Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism. Cell. 158: 659-72. PMID 25083875 DOI: 10.1016/J.Cell.2014.06.050 |
0.489 |
|
| 2014 |
Esquejo RM, Jeon TI, Osborne TF. Lipid-cell cycle nexus: SREBP regulates microRNAs targeting Fbxw7. Cell Cycle (Georgetown, Tex.). 13: 339-40. PMID 24335356 DOI: 10.4161/Cc.27509 |
0.447 |
|
| 2013 |
Jeon TI, Esquejo RM, Roqueta-Rivera M, Phelan PE, Moon YA, Govindarajan SS, Esau CC, Osborne TF. An SREBP-responsive microRNA operon contributes to a regulatory loop for intracellular lipid homeostasis. Cell Metabolism. 18: 51-61. PMID 23823476 DOI: 10.1016/J.Cmet.2013.06.010 |
0.353 |
|
| 2013 |
Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nature Immunology. 14: 489-99. PMID 23563690 DOI: 10.1038/Ni.2570 |
0.4 |
|
| 2012 |
Shin DJ, Joshi P, Hong SH, Mosure K, Shin DG, Osborne TF. Genome-wide analysis of FoxO1 binding in hepatic chromatin: potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis. Nucleic Acids Research. 40: 11499-509. PMID 23066095 DOI: 10.1093/Nar/Gks932 |
0.567 |
|
| 2012 |
Im SS, Osborne TF. Protection from bacterial-toxin-induced apoptosis in macrophages requires the lipogenic transcription factor sterol regulatory element binding protein 1a. Molecular and Cellular Biology. 32: 2196-202. PMID 22493063 DOI: 10.1128/Mcb.06294-11 |
0.561 |
|
| 2012 |
Chong HK, Biesinger J, Seo YK, Xie X, Osborne TF. Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR. Bmc Genomics. 13: 51. PMID 22296850 DOI: 10.1186/1471-2164-13-51 |
0.816 |
|
| 2012 |
Jeon TI, Osborne TF. SREBPs: metabolic integrators in physiology and metabolism. Trends in Endocrinology and Metabolism: Tem. 23: 65-72. PMID 22154484 DOI: 10.1016/J.Tem.2011.10.004 |
0.474 |
|
| 2011 |
Osborne TF. Sterols for Oxygen: The Metabolic Burden of Microbial SREBP. Molecular Cell. 44: 172-4. PMID 22017866 DOI: 10.1016/J.Molcel.2011.10.004 |
0.401 |
|
| 2011 |
Jeong YS, Kim D, Lee YS, Kim HJ, Han JY, Im SS, Chong HK, Kwon JK, Cho YH, Kim WK, Osborne TF, Horton JD, Jun HS, Ahn YH, Ahn SM, et al. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. Plos One. 6: e22544. PMID 21811631 DOI: 10.1371/Journal.Pone.0022544 |
0.814 |
|
| 2011 |
Jeon TI, Seo YK, Osborne TF. Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK. The Biochemical Journal. 438: 33-7. PMID 21592089 DOI: 10.1042/Bj20110009 |
0.37 |
|
| 2011 |
Im SS, Yousef L, Blaschitz C, Liu JZ, Edwards RA, Young SG, Raffatellu M, Osborne TF. Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a. Cell Metabolism. 13: 540-9. PMID 21531336 DOI: 10.1016/J.Cmet.2011.04.001 |
0.471 |
|
| 2011 |
Im SS, Osborne TF. Liver x receptors in atherosclerosis and inflammation. Circulation Research. 108: 996-1001. PMID 21493922 DOI: 10.1161/Circresaha.110.226878 |
0.503 |
|
| 2011 |
Seo YK, Jeon TI, Chong HK, Biesinger J, Xie X, Osborne TF. Genome-wide localization of SREBP-2 in hepatic chromatin predicts a role in autophagy. Cell Metabolism. 13: 367-75. PMID 21459322 DOI: 10.1016/J.Cmet.2011.03.005 |
0.819 |
|
| 2011 |
Blanc M, Hsieh WY, Robertson KA, Watterson S, Shui G, Lacaze P, Khondoker M, Dickinson P, Sing G, Rodríguez-Martín S, Phelan P, Forster T, Strobl B, Müller M, Riemersma R, ... Osborne T, et al. Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis. Plos Biology. 9: e1000598. PMID 21408089 DOI: 10.1371/Journal.Pbio.1000598 |
0.393 |
|
| 2010 |
Lee FY, de Aguiar Vallim TQ, Chong HK, Zhang Y, Liu Y, Jones SA, Osborne TF, Edwards PA. Activation of the farnesoid X receptor provides protection against acetaminophen-induced hepatic toxicity. Molecular Endocrinology (Baltimore, Md.). 24: 1626-36. PMID 20573685 DOI: 10.1210/Me.2010-0117 |
0.808 |
|
| 2010 |
Chong HK, Infante AM, Seo YK, Jeon TI, Zhang Y, Edwards PA, Xie X, Osborne TF. Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1. Nucleic Acids Research. 38: 6007-17. PMID 20483916 DOI: 10.1093/Nar/Gkq397 |
0.819 |
|
| 2010 |
Huang Y, He S, Li JZ, Seo YK, Osborne TF, Cohen JC, Hobbs HH. A feed-forward loop amplifies nutritional regulation of PNPLA3. Proceedings of the National Academy of Sciences of the United States of America. 107: 7892-7. PMID 20385813 DOI: 10.1073/Pnas.1003585107 |
0.481 |
|
| 2010 |
Lee FY, de Aguiar Vallim TQ, Chong HK, Zhang Y, Liu Y, Jones SA, Osborne TF, Edwards PA. Activation of the Farnesoid X-Activated Receptor Provides Protection against Acetaminophen-Induced Hepatic Toxicity The Journal of Clinical Endocrinology & Metabolism. 95: 3563-3563. DOI: 10.1210/Jcem.95.7.9994 |
0.808 |
|
| 2009 |
Osborne TF, Espenshade PJ. Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been. Genes & Development. 23: 2578-91. PMID 19933148 DOI: 10.1101/Gad.1854309 |
0.475 |
|
| 2009 |
Seo YK, Chong HK, Infante AM, Im SS, Xie X, Osborne TF. Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif. Proceedings of the National Academy of Sciences of the United States of America. 106: 13765-9. PMID 19666523 DOI: 10.1073/Pnas.0904246106 |
0.812 |
|
| 2009 |
Im SS, Hammond LE, Yousef L, Nugas-Selby C, Shin DJ, Seo YK, Fong LG, Young SG, Osborne TF. Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2. Molecular and Cellular Biology. 29: 4864-72. PMID 19564420 DOI: 10.1128/Mcb.00553-09 |
0.514 |
|
| 2009 |
Seo YK, Zhu B, Jeon TI, Osborne TF. Regulation of steroid 5-alpha reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin. Experimental Cell Research. 315: 3133-9. PMID 19500568 DOI: 10.1016/J.Yexcr.2009.05.025 |
0.494 |
|
| 2009 |
Okamura M, Kudo H, Wakabayashi K, Tanaka T, Nonaka A, Uchida A, Tsutsumi S, Sakakibara I, Naito M, Osborne TF, Hamakubo T, Ito S, Aburatani H, Yanagisawa M, Kodama T, et al. COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 5819-24. PMID 19307559 DOI: 10.1073/Pnas.0901676106 |
0.357 |
|
| 2009 |
Shin DJ, Osborne TF. FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action. The Journal of Biological Chemistry. 284: 11110-20. PMID 19237543 DOI: 10.1074/jbc.M808747200 |
0.317 |
|
| 2009 |
Im SS, Hammond LE, Yousef L, Nugas-Selby C, Shin DJ, Seo YK, Fong LG, Young SG, Osborne T. Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2 (Molecular and Cellular Biology (2009) 29, 17, (4864-4872)) Molecular and Cellular Biology. 29. DOI: 10.1128/Mcb.01236-09 |
0.514 |
|
| 2008 |
Jeon TI, Zhu B, Larson JL, Osborne TF. SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice Journal of Clinical Investigation. 118: 3693-3700. PMID 18846256 DOI: 10.1172/Jci36461 |
0.391 |
|
| 2008 |
Choi WI, Jeon BN, Park H, Yoo JY, Kim YS, Koh DI, Kim MH, Kim YR, Lee CE, Kim KS, Osborne TF, Hur MW. Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN). The Journal of Biological Chemistry. 283: 29341-54. PMID 18682402 DOI: 10.1074/Jbc.M802477200 |
0.575 |
|
| 2008 |
Ohguchi H, Tanaka T, Uchida A, Magoori K, Kudo H, Kim I, Daigo K, Sakakibara I, Okamura M, Harigae H, Sasaki T, Osborne TF, Gonzalez FJ, Hamakubo T, Kodama T, et al. Hepatocyte nuclear factor 4alpha contributes to thyroid hormone homeostasis by cooperatively regulating the type 1 iodothyronine deiodinase gene with GATA4 and Kruppel-like transcription factor 9. Molecular and Cellular Biology. 28: 3917-31. PMID 18426912 DOI: 10.1128/Mcb.02154-07 |
0.459 |
|
| 2008 |
Bennett MK, Seo YK, Datta S, Shin DJ, Osborne TF. Selective binding of sterol regulatory element-binding protein isoforms and co-regulatory proteins to promoters for lipid metabolic genes in liver. The Journal of Biological Chemistry. 283: 15628-37. PMID 18413311 DOI: 10.1074/Jbc.M800391200 |
0.816 |
|
| 2008 |
Shin DJ, Osborne TF. Peroxisome proliferator-activated receptor-gamma coactivator-1alpha activation of CYP7A1 during food restriction and diabetes is still inhibited by small heterodimer partner. The Journal of Biological Chemistry. 283: 15089-96. PMID 18385139 DOI: 10.1074/Jbc.M710452200 |
0.325 |
|
| 2008 |
Park HJ, Georgescu SP, Du C, Madias C, Aronovitz MJ, Welzig CM, Wang B, Begley U, Zhang Y, Blaustein RO, Patten RD, Karas RH, Van Tol HH, Osborne TF, Shimano H, et al. Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP. The Journal of Clinical Investigation. 118: 259-71. PMID 18060044 DOI: 10.1172/Jci32011 |
0.408 |
|
| 2008 |
JEON TI, Zhu B, Larson J, Osborne TF. SREBP2 regulation of cholecystokinin secretion through activation of bitter taste receptor expression and signaling in murine enteroendocrine cells The Faseb Journal. 22: 139-139. DOI: 10.1096/Fasebj.22.2_Supplement.139 |
0.377 |
|
| 2007 |
Lee H, Hubbert ML, Osborne TF, Woodford K, Zerangue N, Edwards PA. Regulation of the sodium/sulfate co-transporter by farnesoid X receptor alpha. The Journal of Biological Chemistry. 282: 21653-61. PMID 17545158 DOI: 10.1074/Jbc.M700897200 |
0.424 |
|
| 2007 |
Matsukuma KE, Wang L, Bennett MK, Osborne TF. A key role for orphan nuclear receptor liver receptor homologue-1 in activation of fatty acid synthase promoter by liver X receptor. The Journal of Biological Chemistry. 282: 20164-71. PMID 17522048 DOI: 10.1074/Jbc.M702895200 |
0.76 |
|
| 2007 |
Sumi K, Tanaka T, Uchida A, Magoori K, Urashima Y, Ohashi R, Ohguchi H, Okamura M, Kudo H, Daigo K, Maejima T, Kojima N, Sakakibara I, Jiang S, Hasegawa G, ... ... Osborne TF, et al. Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8. Molecular and Cellular Biology. 27: 4248-60. PMID 17403900 DOI: 10.1128/Mcb.01894-06 |
0.574 |
|
| 2006 |
Matsukuma KE, Bennett MK, Huang J, Wang L, Gil G, Osborne TF. Coordinated control of bile acids and lipogenesis through FXR-dependent regulation of fatty acid synthase. Journal of Lipid Research. 47: 2754-61. PMID 16957179 DOI: 10.1194/Jlr.M600342-Jlr200 |
0.759 |
|
| 2006 |
Shin DJ, Plateroti M, Samarut J, Osborne TF. Two uniquely arranged thyroid hormone response elements in the far upstream 5' flanking region confer direct thyroid hormone regulation to the murine cholesterol 7alpha hydroxylase gene. Nucleic Acids Research. 34: 3853-61. PMID 16899449 DOI: 10.1093/Nar/Gkl506 |
0.483 |
|
| 2006 |
Datta S, Wang L, Moore DD, Osborne TF. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter by nuclear receptors liver receptor homologue-1 and small heterodimer partner: a mechanism for differential regulation of cholesterol synthesis and uptake. The Journal of Biological Chemistry. 281: 807-12. PMID 16282330 DOI: 10.1074/Jbc.M511050200 |
0.771 |
|
| 2005 |
Iguchi H, Ikeda Y, Okamura M, Tanaka T, Urashima Y, Ohguchi H, Takayasu S, Kojima N, Iwasaki S, Ohashi R, Jiang S, Hasegawa G, Ioka RX, Magoori K, Sumi K, ... ... Osborne TF, et al. SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice. The Journal of Biological Chemistry. 280: 37669-80. PMID 16148004 DOI: 10.1074/Jbc.M505392200 |
0.335 |
|
| 2005 |
Zoumi A, Datta S, Liaw LH, Wu CJ, Manthripragada G, Osborne TF, Lamorte VJ. Spatial distribution and function of sterol regulatory element-binding protein 1a and 2 homo- and heterodimers by in vivo two-photon imaging and spectroscopy fluorescence resonance energy transfer. Molecular and Cellular Biology. 25: 2946-56. PMID 15798184 DOI: 10.1128/Mcb.25.8.2946-2956.2005 |
0.763 |
|
| 2005 |
Datta S, Osborne TF. Activation domains from both monomers contribute to transcriptional stimulation by sterol regulatory element-binding protein dimers. The Journal of Biological Chemistry. 280: 3338-45. PMID 15550381 DOI: 10.1074/Jbc.M411222200 |
0.772 |
|
| 2005 |
Zhang C, Shin DJ, Osborne TF. A simple promoter containing two Sp1 sites controls the expression of sterol-regulatory-element-binding protein 1a (SREBP-1a). The Biochemical Journal. 386: 161-8. PMID 15462672 DOI: 10.1042/Bj20041514 |
0.509 |
|
| 2004 |
Mullen E, Brown RM, Osborne TF, Shay NF. Soy isoflavones affect sterol regulatory element binding proteins (SREBPs) and SREBP-regulated genes in HepG2 cells. The Journal of Nutrition. 134: 2942-7. PMID 15514256 DOI: 10.1093/Jn/134.11.2942 |
0.533 |
|
| 2004 |
Toth JI, Datta S, Athanikar JN, Freedman LP, Osborne TF. Selective coactivator interactions in gene activation by SREBP-1a and -1c. Molecular and Cellular Biology. 24: 8288-300. PMID 15340088 DOI: 10.1128/Mcb.24.18.8288-8300.2004 |
0.783 |
|
| 2004 |
Bennett MK, Toth JI, Osborne TF. Selective association of sterol regulatory element-binding protein isoforms with target promoters in vivo. The Journal of Biological Chemistry. 279: 37360-7. PMID 15220339 DOI: 10.1074/Jbc.M404693200 |
0.797 |
|
| 2004 |
Worgall TS, Davis-Hayman SR, Magana MM, Oelkers PM, Zapata F, Juliano RA, Osborne TF, Nash TE, Deckelbaum RJ. Sterol and fatty acid regulatory pathways in a Giardia lamblia-derived promoter: evidence for SREBP as an ancient transcription factor. Journal of Lipid Research. 45: 981-8. PMID 14967824 DOI: 10.1194/Jlr.M400024-Jlr200 |
0.594 |
|
| 2003 |
Shin DJ, Campos JA, Gil G, Osborne TF. PGC-1alpha activates CYP7A1 and bile acid biosynthesis. The Journal of Biological Chemistry. 278: 50047-52. PMID 14522988 DOI: 10.1074/Jbc.M309736200 |
0.374 |
|
| 2003 |
Shin DJ, Osborne TF. Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2). The Journal of Biological Chemistry. 278: 34114-8. PMID 12829694 DOI: 10.1074/Jbc.M305417200 |
0.463 |
|
| 2003 |
LaMorte VJ, Zoumi A, Datta S, Wu CJ, Osborne TF. Utilization of Two-Photon FRET to Monitor SREBP Homodimer and Heterodimer Formation In Living Cells Proceedings of Spie - the International Society For Optical Engineering. 4963: 160-164. DOI: 10.1117/12.478034 |
0.756 |
|
| 2003 |
Shin DJ, Campos JA, Gil G, Osborne TF. PGC-1α Activates CYP7A1 and Bile Acid Biosynthesis Journal of Biological Chemistry. 278: 50047-50052. DOI: 10.1074/jbc.M309736200 |
0.305 |
|
| 2002 |
Park HJ, Begley U, Kong D, Yu H, Yin L, Hillgartner FB, Osborne TF, Galper JB. Role of sterol regulatory element binding proteins in the regulation of Galpha(i2) expression in cultured atrial cells. Circulation Research. 91: 32-7. PMID 12114319 DOI: 10.1161/01.RES.0000026502.79063.66 |
0.463 |
|
| 2002 |
Ngo TT, Bennett MK, Bourgeois AL, Toth JI, Osborne TF. A role for cyclic AMP response element-binding protein (CREB) but not the highly similar ATF-2 protein in sterol regulation of the promoter for 3-hydroxy-3-methylglutaryl coenzyme A reductase. The Journal of Biological Chemistry. 277: 33901-5. PMID 12110665 DOI: 10.1074/Jbc.M202135200 |
0.799 |
|
| 2002 |
Mallampalli RK, Ryan AJ, Carroll JL, Osborne TF, Thomas CP. Lipid deprivation increases surfactant phosphatidylcholine synthesis via a sterol-sensitive regulatory element within the CTP:phosphocholine cytidylyltransferase promoter. The Biochemical Journal. 362: 81-8. PMID 11829742 DOI: 10.1042/Bj3620081 |
0.544 |
|
| 2002 |
Teran-Garcia M, Rufo C, Nakamura MT, Osborne TF, Clarke SD. NF-Y involvement in the polyunsaturated fat inhibition of fatty acid synthase gene transcription. Biochemical and Biophysical Research Communications. 290: 1295-9. PMID 11812004 DOI: 10.1006/Bbrc.2002.6341 |
0.491 |
|
| 2002 |
Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. The Journal of Biological Chemistry. 277: 11019-25. PMID 11790787 DOI: 10.1074/Jbc.M111041200 |
0.755 |
|
| 2001 |
Riquet FB, Tan L, Choy BK, Osaki M, Karsenty G, Osborne TF, Auron PE, Goldring MB. YY1 is a positive regulator of transcription of the Col1a1 gene. The Journal of Biological Chemistry. 276: 38665-72. PMID 11514536 DOI: 10.1074/Jbc.M009881200 |
0.427 |
|
| 2001 |
Osborne TF. CREating a SCAP-less liver keeps SREBPs pinned in the ER membrane and prevents increased lipid synthesis in response to low cholesterol and high insulin. Genes & Development. 15: 1873-8. PMID 11485982 DOI: 10.1101/Gad.916601 |
0.362 |
|
| 2001 |
Ikeda Y, Yamamoto J, Okamura M, Fujino T, Takahashi S, Takeuchi K, Osborne TF, Yamamoto TT, Ito S, Sakai J. Transcriptional regulation of the murine acetyl-CoA synthetase 1 gene through multiple clustered binding sites for sterol regulatory element-binding proteins and a single neighboring site for Sp1. The Journal of Biological Chemistry. 276: 34259-69. PMID 11435428 DOI: 10.1074/Jbc.M103848200 |
0.568 |
|
| 2001 |
Christenson LK, Osborne TF, McAllister JM, Strauss JF. Conditional response of the human steroidogenic acute regulatory protein gene promoter to sterol regulatory element binding protein-1a. Endocrinology. 142: 28-36. PMID 11145563 DOI: 10.1210/Endo.142.1.7867 |
0.421 |
|
| 2000 |
Osborne TF. Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. The Journal of Biological Chemistry. 275: 32379-82. PMID 10934219 DOI: 10.1074/Jbc.R000017200 |
0.439 |
|
| 2000 |
Bennett MK, Osborne TF. Nutrient regulation of gene expression by the sterol regulatory element binding proteins: increased recruitment of gene-specific coregulatory factors and selective hyperacetylation of histone H3 in vivo. Proceedings of the National Academy of Sciences of the United States of America. 97: 6340-4. PMID 10841543 DOI: 10.1073/PNAS.97.12.6340 |
0.494 |
|
| 2000 |
Magaña MM, Koo SH, Towle HC, Osborne TF. Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. The Journal of Biological Chemistry. 275: 4726-33. PMID 10671504 DOI: 10.1074/Jbc.275.7.4726 |
0.534 |
|
| 1999 |
Bennett MK, Ngo TT, Athanikar JN, Rosenfeld JM, Osborne TF. Co-stimulation of promoter for low density lipoprotein receptor gene by sterol regulatory element-binding protein and Sp1 is specifically disrupted by the yin yang 1 protein. The Journal of Biological Chemistry. 274: 13025-32. PMID 10224053 DOI: 10.1074/Jbc.274.19.13025 |
0.539 |
|
| 1999 |
Dooley KA, Bennett MK, Osborne TF. A critical role for cAMP response element-binding protein (CREB) as a Co-activator in sterol-regulated transcription of 3-hydroxy-3-methylglutaryl coenzyme A synthase promoter. The Journal of Biological Chemistry. 274: 5285-91. PMID 10026135 DOI: 10.1074/Jbc.274.9.5285 |
0.552 |
|
| 1998 |
Osborne TF, LaMorte VJ. Molecular aspects in feedback regulation of gene expression by cholesterol in mammalian cells. Methods (San Diego, Calif.). 16: 42-8. PMID 9774515 DOI: 10.1006/Meth.1998.0643 |
0.471 |
|
| 1998 |
Worgall TS, Sturley SL, Seo T, Osborne TF, Deckelbaum RJ. Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element- binding protein Journal of Biological Chemistry. 273: 25537-25540. PMID 9748213 DOI: 10.1074/Jbc.273.40.25537 |
0.464 |
|
| 1998 |
Chouinard RA, Luo Y, Osborne TF, Walsh A, Tall AR. Sterol regulatory element binding protein-1 activates the cholesteryl ester transfer protein gene in vivo but is not required for sterol up-regulation of gene expression. The Journal of Biological Chemistry. 273: 22409-14. PMID 9712863 DOI: 10.1074/jbc.273.35.22409 |
0.447 |
|
| 1998 |
Rosenfeld JM, Osborne TF. HLH106, a Drosophila sterol regulatory element-binding protein in a natural cholesterol auxotroph. The Journal of Biological Chemistry. 273: 16112-21. PMID 9632664 DOI: 10.1074/Jbc.273.26.16112 |
0.541 |
|
| 1998 |
Athanikar JN, Osborne TF. Specificity in cholesterol regulation of gene expression by coevolution of sterol regulatory DNA element and its binding protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 4935-40. PMID 9560206 DOI: 10.1073/PNAS.95.9.4935 |
0.458 |
|
| 1998 |
Osborne TF, Rosenfeld JM. Related membrane domains in proteins of sterol sensing and cell signaling provide a glimpse of treasures still buried within the dynamic realm of intracellular metabolic regulation. Current Opinion in Lipidology. 9: 137-40. PMID 9559271 DOI: 10.1097/00041433-199804000-00010 |
0.482 |
|
| 1998 |
Dooley KA, Millinder S, Osborne TF. Sterol regulation of 3-hydroxy-3-methylglutaryl-coenzyme A synthase gene through a direct interaction between sterol regulatory element binding protein and the trimeric CCAAT-binding factor/nuclear factor Y. The Journal of Biological Chemistry. 273: 1349-56. PMID 9430668 DOI: 10.1074/Jbc.273.3.1349 |
0.562 |
|
| 1997 |
Athanikar JN, Sanchez HB, Osborne TF. Promoter selective transcriptional synergy mediated by sterol regulatory element binding protein and Sp1: A critical role for the Btd domain of Sp1 Molecular and Cellular Biology. 17: 5193-5200. PMID 9271397 DOI: 10.1128/Mcb.17.9.5193 |
0.515 |
|
| 1997 |
Osborne TF. Cholesterol homeostasis: clipping out a slippery regulator. Current Biology : Cb. 7: R172-4. PMID 9162482 DOI: 10.1016/S0960-9822(97)70081-2 |
0.442 |
|
| 1997 |
Guan G, Dai PH, Osborne TF, Kim JB, Shechter I. Multiple sequence elements are involved in the transcriptional regulation of the human squalene synthase gene. The Journal of Biological Chemistry. 272: 10295-302. PMID 9092581 DOI: 10.1074/Jbc.272.15.10295 |
0.506 |
|
| 1997 |
Magaña MM, Osborne TF. Two tandem binding sites for sterol regulatory element binding proteins are required for sterol regulation of fatty-acid synthase promoter. The Journal of Biological Chemistry. 271: 32689-94. PMID 8955100 DOI: 10.1074/Jbc.271.51.32689 |
0.516 |
|
| 1996 |
Osborne TF. Transcriptional control mechanisms in the regulation of cholesterol balance. Critical Reviews in Eukaryotic Gene Expression. 5: 317-35. PMID 8834229 DOI: 10.1615/Critreveukargeneexpr.V5.I3-4.50 |
0.489 |
|
| 1996 |
Vallett SM, Sanchez HB, Rosenfeld JM, Osborne TF. A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene Journal of Biological Chemistry. 271: 12247-12253. PMID 8647822 DOI: 10.1074/Jbc.271.21.12247 |
0.563 |
|
| 1996 |
Lopez JM, Bennett MK, Sanchez HB, Rosenfeld JM, Osborne TF. Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid. Proceedings of the National Academy of Sciences of the United States of America. 93: 1049-53. PMID 8577712 DOI: 10.1073/pnas.93.3.1049 |
0.479 |
|
| 1995 |
Sanchez HB, Yieh L, Osborne TF. Cooperation by sterol regulatory element-binding protein and Sp1 in sterol regulation of low density lipoprotein receptor gene Journal of Biological Chemistry. 270: 1161-1169. PMID 7836375 DOI: 10.1074/Jbc.270.3.1161 |
0.536 |
|
| 1995 |
Vallett SM, Osborne TF. Two separate sites contribute to AP-1 activation of the promoter for 3-hydroxy-3-methylglutaryl coenzyme A synthase. Nucleic Acids Research. 22: 5184-9. PMID 7816604 DOI: 10.1093/Nar/22.24.5184 |
0.438 |
|
| 1995 |
Jackson SM, Ericsson J, Osborne TF, Edwards PA. NF-Y has a novel role in sterol-dependent transcription of two cholesterogenic genes. The Journal of Biological Chemistry. 270: 21445-8. PMID 7665553 DOI: 10.1074/Jbc.270.37.21445 |
0.554 |
|
| 1995 |
Yieh L, Sanchez HB, Osborne TF. Domains of transcription factor Sp1 required for synergistic activation with sterol regulatory element binding protein 1 of low density lipoprotein receptor promoter Proceedings of the National Academy of Sciences of the United States of America. 92: 6102-6106. PMID 7597088 DOI: 10.1073/pnas.92.13.6102 |
0.447 |
|
| 1995 |
Bennett MK, Lopez JM, Sanchez HB, Osborne TF. Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways. The Journal of Biological Chemistry. 270: 25578-83. PMID 7592729 DOI: 10.1074/Jbc.270.43.25578 |
0.581 |
|
| 1991 |
Chu HM, Fischer WH, Osborne TF, Comb MJ. NF-I proteins from brain interact with the proenkephalin cAMP inducible enhancer. Nucleic Acids Research. 19: 2721-8. PMID 1828294 DOI: 10.1093/Nar/19.10.2721 |
0.487 |
|
| 1988 |
Gil G, Smith JR, Goldstein JL, Slaughter CA, Orth K, Brown MS, Osborne TF. Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Proceedings of the National Academy of Sciences of the United States of America. 85: 8963-7. PMID 3194401 DOI: 10.1073/Pnas.85.23.8963 |
0.325 |
|
| 1987 |
Osborne TF, Gil G, Brown MS, Kowal RC, Goldstein JL. Identification of promoter elements required for in vitro transcription of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase gene. Proceedings of the National Academy of Sciences of the United States of America. 84: 3614-8. PMID 3473472 DOI: 10.1073/pnas.84.11.3614 |
0.387 |
|
| 1985 |
Osborne TF, Goldstein JL, Brown MS. 5' end of HMG CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription. Cell. 42: 203-12. PMID 3860301 DOI: 10.1016/S0092-8674(85)80116-1 |
0.406 |
|
| 1984 |
Osborne TF, Arvidson DN, Tyau ES, Dunsworth-Browne M, Berk AJ. Transcription control region within the protein-coding portion of adenovirus E1A genes Molecular and Cellular Biology. 4: 1293-1305. PMID 6334230 DOI: 10.1128/Mcb.4.7.1293 |
0.389 |
|
| 1984 |
Reynolds GA, Basu SK, Osborne TF, Chin DJ, Gil G, Brown MS, Goldstein JL, Luskey KL. HMG CoA reductase: a negatively regulated gene with unusual promoter and 5' untranslated regions. Cell. 38: 275-85. PMID 6088070 DOI: 10.1016/0092-8674(84)90549-X |
0.388 |
|
| 1982 |
Osborne TF, Gaynor RB, Berk AJ. The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions Cell. 29: 139-148. PMID 7105179 DOI: 10.1016/0092-8674(82)90098-8 |
0.354 |
|
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