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Mark G. McNamee - Publications

Affiliations: 
1975-2001 Biochemistry and Biophysics University of California, Davis, Davis, CA 
 2001- Biochemistry and biological sciences Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Area:
structure and function of biological membranes
Website:
http://www.provost.vt.edu/about/mcnamee_bio.html

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2001 Cruz-Martín A, Mercado JL, Rojas LV, McNamee MG, Lasalde-Dominicci JA. Tryptophan substitutions at lipid-exposed positions of the gamma M3 transmembrane domain increase the macroscopic ionic current response of the Torpedo californica nicotinic acetylcholine receptor. The Journal of Membrane Biology. 183: 61-70. PMID 11547353 DOI: 10.1007/S00232-001-0051-Z  0.381
2000 Tamamizu S, Guzmán GR, Santiago J, Rojas LV, McNamee MG, Lasalde-Dominicci JA. Functional effects of periodic tryptophan substitutions in the alpha M4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Biochemistry. 39: 4666-73. PMID 10769122 DOI: 10.1021/Bi992835W  0.439
1999 Tamamizu S, Lee Y, Hung B, McNamee MG, Lasalde-Dominicci JA. Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain. The Journal of Membrane Biology. 170: 157-64. PMID 10430659 DOI: 10.1007/S002329900545  0.369
1998 Kim J, McNamee MG. Topological disposition of Cys 222 in the alpha-subunit of nicotinic acetylcholine receptor analyzed by fluorescence-quenching and electron paramagnetic resonance measurements. Biochemistry. 37: 4680-6. PMID 9521789 DOI: 10.1021/Bi972666K  0.439
1997 Ortiz-Miranda SI, Lasalde JA, Pappone PA, McNamee MG. Mutations in the M4 domain of the Torpedo californica nicotinic acetylcholine receptor alter channel opening and closing. The Journal of Membrane Biology. 158: 17-30. PMID 9211718 DOI: 10.1007/S002329900240  0.378
1997 Gomez CM, Maselli R, Gundeck JE, Chao M, Day JW, Tamamizu S, Lasalde JA, McNamee M, Wollmann RL. Slow-channel transgenic mice: a model of postsynaptic organellar degeneration at the neuromuscular junction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4170-9. PMID 9151734 DOI: 10.1523/Jneurosci.17-11-04170.1997  0.313
1997 Butler DH, Lasalde JA, Butler JK, Tamamizu S, Zimmerman G, McNamee MG. Mouse-Torpedo chimeric alpha-subunit used to probe channel-gating determinants on the nicotinic acetylcholine receptor primary sequence. Cellular and Molecular Neurobiology. 17: 13-33. PMID 9118205 DOI: 10.1023/A:1026372903352  0.388
1996 Lasalde JA, Tamamizu S, Butler DH, Vibat CR, Hung B, McNamee MG. Tryptophan substitutions at the lipid-exposed transmembrane segment M4 of Torpedo californica acetylcholine receptor govern channel gating. Biochemistry. 35: 14139-48. PMID 8916899 DOI: 10.1021/Bi961583L  0.367
1996 Tamamizu S, Butler DH, Lasalde JA, McNamee MG. Effects of antibody binding on structural transitions of the nicotinic acetylcholine receptor. Biochemistry. 35: 11773-81. PMID 8794758 DOI: 10.1021/Bi960369U  0.41
1996 Gomez CM, Maselli R, Gammack J, Lasalde J, Tamamizu S, Cornblath DR, Lehar M, McNamee M, Kuncl RW. A β-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome Annals of Neurology. 39: 712-723. PMID 8651643 DOI: 10.1002/Ana.410390607  0.336
1995 Tamamizu S, Todd AP, McNamee MG. Mutations in the M1 region of the nicotinic acetylcholine receptor alter the sensitivity to inhibition by quinacrine. Cellular and Molecular Neurobiology. 15: 427-38. PMID 8565046 DOI: 10.1007/Bf02071878  0.404
1995 Vibat CR, Lasalde JA, McNamee MG, Ochoa EL. Differential desensitization properties of rat neuronal nicotinic acetylcholine receptor subunit combinations expressed in Xenopus laevis oocytes. Cellular and Molecular Neurobiology. 15: 411-25. PMID 8565045 DOI: 10.1007/Bf02071877  0.396
1994 Lee YH, Li L, Lasalde J, Rojas L, McNamee M, Ortiz-Miranda SI, Pappone P. Mutations in the M4 domain of Torpedo californica acetylcholine receptor dramatically alter ion channel function Biophysical Journal. 66: 646-653. PMID 7516721 DOI: 10.1016/S0006-3495(94)80838-0  0.442
1994 Sunshine C, McNamee MG. Lipid modulation of nicotinic acetylcholine receptor function: the role of membrane lipid composition and fluidity. Biochimica Et Biophysica Acta. 1191: 59-64. PMID 7512384 DOI: 10.1016/0005-2736(94)90233-X  0.479
1993 Bhushan A, McNamee MG. Correlation of phospholipid structure with functional effects on the nicotinic acetylcholine receptor. A modulatory role for phosphatidic acid. Biophysical Journal. 64: 716-23. PMID 8471723 DOI: 10.1016/S0006-3495(93)81431-0  0.523
1993 Eterovi? VA, Li L, Ferchmin PA, Lee YH, Hann RM, Rodriguez AD, McNamee MG. The ion channel of muscle and electric organ acetylcholine receptors: differing affinities for noncompetitive inhibitors. Cellular and Molecular Neurobiology. 13: 111-21. PMID 8394213 DOI: 10.1007/Bf00735368  0.474
1993 Butler DH, McNamee MG. FTIR analysis of nicotinic acetylcholine receptor secondary structure in reconstituted membranes. Biochimica Et Biophysica Acta. 1150: 17-24. PMID 8392868 DOI: 10.1016/0005-2736(93)90116-H  0.438
1993 Thomas TC, Székács A, Hammock BD, Wilson BW, McNamee MG. Affinity chromatography of neuropathy target esterase. Chemico-Biological Interactions. 87: 347-60. PMID 8343992 DOI: 10.1016/0009-2797(93)90063-5  0.361
1993 Narayanaswami V, McNamee MG. Protein-lipid interactions and Torpedo californica nicotinic acetylcholine receptor function. 2. Membrane fluidity and ligand-mediated alteration in the accessibility of gamma subunit cysteine residues to cholesterol. Biochemistry. 32: 12420-7. PMID 8241132 DOI: 10.1021/Bi00097A021  0.484
1993 Narayanaswami V, Kim J, McNamee MG. Protein-lipid interactions and Torpedo californica nicotinic acetylcholine receptor function. 1. Spatial disposition of cysteine residues in the gamma subunit analyzed by fluorescence-quenching and energy-transfer measurements. Biochemistry. 32: 12413-9. PMID 8241131 DOI: 10.1021/Bi00097A020  0.455
1993 Eterovi? VA, Hann RM, Ferchmin PA, Rodriguez AD, Li L, Lee YH, McNamee MG. Diterpenoids from Caribbean gorgonians act as noncompetitive inhibitors of the nicotinic acetylcholine receptor. Cellular and Molecular Neurobiology. 13: 99-110. PMID 8102324 DOI: 10.1007/Bf00735367  0.478
1992 Li L, McNamee MG. Modulation of nicotinic acetylcholine receptor channel by pH: a difference in pH sensitivity of Torpedo and mouse receptors expressed in Xenopus oocytes. Cellular and Molecular Neurobiology. 12: 83-93. PMID 1600556 DOI: 10.1007/Bf00713363  0.355
1992 Li L, Lee YH, Pappone P, Palma A, McNamee MG. Site-specific mutations of nicotinic acetylcholine receptor at the lipid-protein interface dramatically alter ion channel gating. Biophysical Journal. 62: 61-3. PMID 1600100 DOI: 10.1016/S0006-3495(92)81779-4  0.371
1992 Sunshine C, McNamee MG. Lipid modulation of nicotinic acetylcholine receptor function: the role of neutral and negatively charged lipids. Biochimica Et Biophysica Acta. 1108: 240-6. PMID 1379073 DOI: 10.1016/0005-2736(92)90031-G  0.468
1991 Palma A, Li L, Chen X, Pappone P, McNamee M. Effects of pH on acetylcholine receptor function The Journal of Membrane Biology. 120: 67-73. PMID 2020020 DOI: 10.1007/Bf01868592  0.384
1991 Chattopadhyay A, McNamee MG. Average membrane penetration depth of tryptophan residues of the nicotinic acetylcholine receptor by the parallax method. Biochemistry. 30: 7159-64. PMID 1854727 DOI: 10.1021/Bi00243A017  0.662
1991 Wilson KJ, McNamee MG, Peticolas WL. The time dependent UV resonance Raman spectra, conformation, and biological activity of acetylcholine analogues upon binding to acetylcholine binding proteins. Journal of Biomolecular Structure & Dynamics. 9: 489-509. PMID 1726137 DOI: 10.1080/07391102.1991.10507931  0.391
1990 Bhushan A, McNamee MG. Differential scanning calorimetry and Fourier transform infrared analysis of lipid-protein interactions involving the nicotinic acetylcholine receptor. Biochimica Et Biophysica Acta. 1027: 93-101. PMID 2397225 DOI: 10.1016/0005-2736(90)90053-Q  0.408
1990 Thomas TC, Székács A, Rojas S, Hammock BD, Wilson BW, McNamee MG. Characterization of neuropathy target esterase using trifluoromethyl ketones. Biochemical Pharmacology. 40: 2587-96. PMID 2260984 DOI: 10.1016/0006-2952(90)90575-6  0.31
1990 Eterovi? VA, Li L, Palma A, McNamee MG. Regulation of nicotinic acetylcholine receptor function by adenine nucleotides. Cellular and Molecular Neurobiology. 10: 423-33. PMID 2253264 DOI: 10.1007/Bf00711184  0.425
1990 Ochoa EL, Li LA, Plummer A, McNamee MG. Direct effects of thymopentin (Arg-Lys-Asp-Val-Tyr) on cholinergic agonist-induced slow inactivation of nicotinic acetylcholine receptor function. Molecular Pharmacology. 38: 863-71. PMID 2250665  0.391
1990 Thomas TC, McNamee MG. Purification of membrane proteins. Methods in Enzymology. 182: 499-520. PMID 2179666 DOI: 10.1016/0076-6879(90)82040-9  0.316
1990 Ochoa EL, Li L, McNamee MG. Desensitization of central cholinergic mechanisms and neuroadaptation to nicotine. Molecular Neurobiology. 4: 251-87. PMID 2135395 DOI: 10.1007/Bf02780343  0.368
1990 Li L, Schuchard M, Palma A, Pradier L, McNamee MG. Functional role of the cysteine 451 thiol group in the M4 helix of the gamma subunit of Torpedo californica acetylcholine receptor. Biochemistry. 29: 5428-36. PMID 1696834 DOI: 10.1021/Bi00475A003  0.448
1989 Thomas TC, Ishikawa Y, McNamee MG, Wilson BW. Correlation of neuropathy target esterase activity with specific tritiated di-isopropyl phosphorofluoridate-labelled proteins. The Biochemical Journal. 257: 109-16. PMID 2920006 DOI: 10.1042/Bj2570109  0.313
1989 Pradier L, Yee AS, McNamee MG. Use of chemical modifications and site-directed mutagenesis to probe the functional role of thiol groups on the gamma subunit of Torpedo californica acetylcholine receptor. Biochemistry. 28: 6562-71. PMID 2790013 DOI: 10.1021/Bi00442A006  0.441
1989 McNamee MG. Isolation and characterization of cell membranes. Biotechniques. 7: 466-75. PMID 2699236  0.309
1989 Ochoa EL, Chattopadhyay A, McNamee MG. Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators. Cellular and Molecular Neurobiology. 9: 141-78. PMID 2663167 DOI: 10.1007/Bf00713026  0.647
1988 Jones OT, Eubanks JH, Earnest JP, McNamee MG. A minimum number of lipids are required to support the functional properties of the nicotinic acetylcholine receptor. Biochemistry. 27: 3733-42. PMID 3408723 DOI: 10.1021/Bi00410A032  0.531
1988 Jones OT, McNamee MG. Annular and nonannular binding sites for cholesterol associated with the nicotinic acetylcholine receptor. Biochemistry. 27: 2364-74. PMID 3382628 DOI: 10.1021/Bi00407A018  0.523
1988 Jones OT, Eubanks JH, Earnest JP, McNamee MG. Reconstitution of the nicotinic acetylcholine receptor using a lipid substitution technique. Biochimica Et Biophysica Acta. 944: 359-66. PMID 2460140 DOI: 10.1016/0005-2736(88)90506-8  0.417
1987 Medrano S, Ochoa EL, McNamee MG. The effect of amantadine on nicotinic acetylcholine receptor (nAchR) in reconstituted membranes. Neurochemistry International. 11: 175-81. PMID 20501159 DOI: 10.1016/0197-0186(87)90007-6  0.502
1987 Fong TM, McNamee MG. Stabilization of acetylcholine receptor secondary structure by cholesterol and negatively charged phospholipids in membranes. Biochemistry. 26: 3871-80. PMID 3651419 DOI: 10.1021/Bi00387A020  0.437
1986 Yee AS, Corley DE, McNamee MG. Thiol-group modification of Torpedo californica acetylcholine receptor: subunit localization and effects on function. Biochemistry. 25: 2110-9. PMID 3707936 DOI: 10.1021/Bi00356A040  0.482
1986 Earnest JP, Limbacher HP, McNamee MG, Wang HH. Binding of local anesthetics to reconstituted acetylcholine receptors: effect of protein surface potential. Biochemistry. 25: 5809-18. PMID 3022805  0.413
1986 Fong TM, McNamee MG. Correlation between acetylcholine receptor function and structural properties of membranes. Biochemistry. 25: 830-40. PMID 3008814 DOI: 10.1021/Bi00352A015  0.478
1985 Kemp G, Bentley L, McNamee MG, Morley BJ. Purification and characterization of the alpha-bungarotoxin binding protein from rat brain. Brain Research. 347: 274-83. PMID 4063809 DOI: 10.1016/0006-8993(85)90187-8  0.344
1985 Yee AS, McNamee MG. Effects of carboxymethylation by a purified Torpedo californica methylase on the functional properties of the acetylcholine receptor in reconstituted membranes. Archives of Biochemistry and Biophysics. 243: 349-60. PMID 2417559 DOI: 10.1016/0003-9861(85)90512-0  0.525
1984 McNamee M, Richardson C, Walker J. Activation and Inactivation Kinetics of Torpedo californica Acetylcholine Receptor in Reconstituted Membranes. Biophysical Journal. 45: 18-20. PMID 19431548 DOI: 10.1016/S0006-3495(84)84091-6  0.712
1984 Earnest JP, Wang HH, McNamee MG. Multiple binding sites for local anesthetics on reconstituted acetylcholine receptor membranes. Biochemical and Biophysical Research Communications. 123: 862-8. PMID 6091643 DOI: 10.1016/0006-291X(84)90310-3  0.484
1984 Walker JW, Richardson CA, McNamee MG. Effects of thio-group modifications of Torpedo californica acetylcholine receptor on ion flux activation and inactivation kinetics. Biochemistry. 23: 2329-38. PMID 6089867 DOI: 10.1021/Bi00306A002  0.695
1983 Ochoa EL, Dalziel AW, McNamee MG. Reconstitution of acetylcholine receptor function in lipid vesicles of defined composition. Biochimica Et Biophysica Acta. 727: 151-62. PMID 6824649 DOI: 10.1016/0005-2736(83)90379-6  0.525
1983 Ellena JF, Blazing MA, McNamee MG. Lipid-protein interactions in reconstituted membranes containing acetylcholine receptor. Biochemistry. 22: 5523-35. PMID 6317021 DOI: 10.1021/Bi00293A012  0.476
1982 McNamee MG, Ellena JF, Dalziel AW. Lipid-protein interactions in membranes containing the acetylcholine receptor. Biophysical Journal. 37: 103-4. PMID 19431426 DOI: 10.1016/S0006-3495(82)84622-5  0.487
1982 Hess GP, Pasquale EB, Walker JW, McNamee MG. Comparison of acetylcholine receptor-controlled cation flux in membrane vesicles from Torpedo californica and Electrophorus electricus: chemical kinetic measurements in the millisecond region. Proceedings of the National Academy of Sciences of the United States of America. 79: 963-7. PMID 6951180 DOI: 10.1073/Pnas.79.4.963  0.729
1982 McNamee MG, Ochoa EL. Reconstitution of acetylcholine receptor function in model membranes. Neuroscience. 7: 2305-19. PMID 6757782 DOI: 10.1016/0306-4522(82)90197-X  0.405
1982 Walker JW, Takeyasu K, McNamee MG. Activation and inactivation kinetics of Torpedo californica acetylcholine receptor in reconstituted membranes. Biochemistry. 21: 5384-9. PMID 6293538 DOI: 10.1021/Bi00265A001  0.675
1981 Walker JW, McNamee MG, Pasquale E, Cash DJ, Hess GP. Acetylcholine receptor inactivation in Torpedo californica electroplax membrane vesicles. Detection of two processes in the millisecond and second time regions. Biochemical and Biophysical Research Communications. 100: 86-90. PMID 7259763 DOI: 10.1016/S0006-291X(81)80066-6  0.72
1981 Walker JW, Lukas RJ, McNamee MG. Effects of thio-group modifications on the ion permeability control and ligand binding properties of Torpedo californica acetylcholine receptor. Biochemistry. 20: 2191-9. PMID 7236589 DOI: 10.1021/Bi00511A018  0.713
1981 Weidoff PM, McNamee MG, Wilson BW. Alteration of acetylcholine receptor and acetylcholinesterase metabolism by actinomycin D in cultured muscle cells. Canadian Journal of Physiology and Pharmacology. 59: 580-5. PMID 6170404 DOI: 10.1139/Y81-087  0.351
1980 Ellena JF, McNamee MG. Interaction of spin-labeled Naja naja siamensis alpha-neurotoxin with acetylcholine receptor from Torpedo californica. Febs Letters. 110: 301-4. PMID 7371834 DOI: 10.1016/0014-5793(80)80097-4  0.374
1980 Delegeane AM, McNamee MG. Independent activation of the acetylcholine receptor from Torpedo californica at two sites. Biochemistry. 19: 890-5. PMID 7356966 DOI: 10.1021/Bi00546A010  0.562
1980 Dalziel AW, Rollins ES, McNamee MG. The effect of cholesterol on agonist-induced flux in reconstituted acetylcholine receptor vesicles. Febs Letters. 122: 193-6. PMID 7202709 DOI: 10.1016/0014-5793(80)80435-2  0.475
1980 Andreasen TJ, McNamee MG. Inhibition of ion permeability control properties of acetylcholine receptor from Torpedo californica by long-chain fatty acids. Biochemistry. 19: 4719-26. PMID 6252956 DOI: 10.1021/Bi00561A027  0.401
1979 Doerge DR, McNamee MG, Ingraham LL. Modification of acetylcholine receptor-mediated ion permeability by thiamine. Molecular Pharmacology. 15: 747-50. PMID 492154  0.365
1979 Andreasen TJ, Doerge DR, McNamee MG. Effects of phospholipase A2 on the binding and ion permeability control properties of the acetylcholine receptor. Archives of Biochemistry and Biophysics. 194: 468-80. PMID 443814 DOI: 10.1016/0003-9861(79)90641-6  0.508
1979 Eckstein TB, Randall WR, McNamee MG. Erythrocyte plasma membrane fluidity in avian muscular dystrophy. Experimental Neurology. 64: 315-26. PMID 428508 DOI: 10.1016/0014-4886(79)90272-3  0.327
1977 Andreasen TJ, McNamee MG. Phospholipase A inhibition of acetylcholine receptor function in Torpedo californica membrane vesicles. Biochemical and Biophysical Research Communications. 79: 958-65. PMID 597318 DOI: 10.1016/0006-291X(77)91203-7  0.553
1977 McNamee MG. Characterization of acetylcholine receptor rich membrane vesicles from Torpedo californica Federation Proceedings. 36: No.1958.  0.441
1977 McNamee MG. Characterization of acetylcholine receptor - rich membrane vesicles from Torpedo californica Journal of Electron Microscopy. 26: 170-171.  0.441
1976 Karlin A, McNamee MG, Cowburn DA. Assay of the acetylcholine receptor by affinity labeling. Analytical Biochemistry. 76: 442-51. PMID 998984 DOI: 10.1016/0003-2697(76)90339-0  0.614
1976 Karlin A, Weill CL, McNamee MG, Valderrama R. Facets of the structures of acetylcholine receptors from Electrophorus and Torpedo. Cold Spring Harbor Symposia On Quantitative Biology. 40: 203-10. PMID 820505 DOI: 10.1101/Sqb.1976.040.01.022  0.587
1976 Valderrama R, Weill CL, McNamee M, Karlin A. Isolation and properties of acetylcholine receptors from Electrophorus and Torpedo. Annals of the New York Academy of Sciences. 274: 108-15. PMID 786105 DOI: 10.1111/J.1749-6632.1976.Tb47679.X  0.576
1975 McNamee MG, Weill CL, Karlin A. Purification of acetylcholine receptor from Torpedo californica and its incorporation into phospholipid vesicles. Annals of the New York Academy of Sciences. 264: 175-82. PMID 1062956 DOI: 10.1111/J.1749-6632.1975.Tb31482.X  0.649
1975 Weill CL, McNamee MG, Valderrama RR, Karlin A. The binding site subunit of the acetylcholine receptor Federation Proceedings. 34: No. 2941.  0.353
1974 Weill CL, McNamee MG, Karlin A. Affinity-labeling of purified acetylcholine receptor from Torpedo californica. Biochemical and Biophysical Research Communications. 61: 997-1003. PMID 4451573 DOI: 10.1016/0006-291X(74)90254-X  0.607
1973 McNamee MG, McConnell HM. Transmembrane potentials and phospholipid flip-flop in excitable membrane vesicles. Biochemistry. 12: 2951-8. PMID 4354249 DOI: 10.1021/Bi00740A001  0.524
1972 Kornberg RD, McNamee MG, McConnell HM. Measurement of transmembrane potentials in phospholipid vesicles. Proceedings of the National Academy of Sciences of the United States of America. 69: 1508-13. PMID 4338594 DOI: 10.1073/Pnas.69.6.1508  0.548
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