| Year |
Citation |
Score |
| 2024 |
Fedeles BI, Bhardwaj R, Ishikawa Y, Khumsubdee S, Krappitz M, Gubina N, Volpe I, Andrade DC, Westergerling P, Staudner T, Campolo J, Liu SS, Dong K, Cai Y, Rehman M, ... ... Fedeles SV, et al. A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 121: e2317344121. PMID 38241440 DOI: 10.1073/pnas.2317344121 |
0.535 |
|
| 2022 |
Liebau MC, Mekahli D, Perrone R, Soyfer B, Fedeles S. Polycystic Kidney Disease Drug Development: A Conference Report. Kidney Medicine. 5: 100596. PMID 36698747 DOI: 10.1016/j.xkme.2022.100596 |
0.314 |
|
| 2022 |
Krappitz M, Bhardwaj R, Dong K, Staudner T, Yilmaz DE, Pioppini C, Westergerling P, Ruemmele D, Hollmann T, Nguyen TA, Cai Y, Gallagher AR, Somlo S, Fedeles S. XBP1 Activation Reduces Severity of Polycystic Kidney Disease due to a Nontruncating Mutation in Mice. Journal of the American Society of Nephrology : Jasn. PMID 36270750 DOI: 10.1681/ASN.2021091180 |
0.653 |
|
| 2020 |
Vien TN, Ng LCT, Smith JM, Dong K, Krappitz M, Gainullin VG, Fedeles S, Harris PC, Somlo S, DeCaen PG. Disrupting Polycystin-2 EF hand Ca affinity does not alter channel function or contribute to polycystic kidney disease. Journal of Cell Science. PMID 33199522 DOI: 10.1242/jcs.255562 |
0.544 |
|
| 2019 |
Ishikawa Y, Fedeles S, Marlier A, Zhang C, Gallagher AR, Lee AH, Somlo S. Spliced XBP1 Rescues Renal Interstitial Inflammation Due to Loss of in Collecting Ducts. Journal of the American Society of Nephrology : Jasn. PMID 30745418 DOI: 10.1681/Asn.2018060614 |
0.686 |
|
| 2017 |
Besse W, Dong K, Choi J, Punia S, Fedeles SV, Choi M, Gallagher AR, Huang EB, Gulati A, Knight J, Mane S, Tahvanainen E, Tahvanainen P, Sanna-Cherchi S, Lifton RP, et al. Isolated polycystic liver disease genes define effectors of polycystin-1 function. The Journal of Clinical Investigation. 127: 3558. PMID 28862642 DOI: 10.1172/Jci96729 |
0.591 |
|
| 2017 |
Besse W, Dong K, Choi J, Punia S, Fedeles SV, Choi M, Gallagher AR, Huang EB, Gulati A, Knight J, Mane S, Tahvanainen E, Tahvanainen P, Sanna-Cherchi S, Lifton RP, et al. Isolated polycystic liver disease genes define effectors of polycystin-1 function. The Journal of Clinical Investigation. PMID 28375157 DOI: 10.1172/Jci90129 |
0.676 |
|
| 2016 |
Krappitz M, Gallagher AR, Fedeles S. Is it Time to Fold the Cysts Away? Trends in Molecular Medicine. 22: 997-999. PMID 27793600 DOI: 10.1016/J.Molmed.2016.10.001 |
0.471 |
|
| 2015 |
Overton JD, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, Fedeles SV, Habas R, Runnels LW. Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Scientific Reports. 5: 18395. PMID 26671672 DOI: 10.1038/Srep18395 |
0.47 |
|
| 2015 |
Hassan H, Tian X, Inoue K, Chai N, Liu C, Soda K, Moeckel G, Tufro A, Lee AH, Somlo S, Fedeles S, Ishibe S. Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes. Journal of the American Society of Nephrology : Jasn. PMID 26303067 DOI: 10.1681/Asn.2015020191 |
0.575 |
|
| 2015 |
Fedeles SV, So JS, Shrikhande A, Lee SH, Gallagher AR, Barkauskas CE, Somlo S, Lee AH. Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity. The Journal of Clinical Investigation. 125: 1955-67. PMID 25844898 DOI: 10.1172/Jci78863 |
0.673 |
|
| 2014 |
Cai Y, Fedeles SV, Dong K, Anyatonwu G, Onoe T, Mitobe M, Gao JD, Okuhara D, Tian X, Gallagher AR, Tang Z, Xie X, Lalioti MD, Lee AH, Ehrlich BE, et al. Altered trafficking and stability of polycystins underlie polycystic kidney disease. The Journal of Clinical Investigation. 124: 5129-44. PMID 25365220 DOI: 10.1172/Jci67273 |
0.637 |
|
| 2014 |
Hofherr A, Wagner C, Fedeles S, Somlo S, Köttgen M. N-glycosylation determines the abundance of the transient receptor potential channel TRPP2. The Journal of Biological Chemistry. 289: 14854-67. PMID 24719335 DOI: 10.1074/Jbc.M114.562264 |
0.618 |
|
| 2014 |
Yuajit C, Muanprasat C, Gallagher AR, Fedeles SV, Kittayaruksakul S, Homvisasevongsa S, Somlo S, Chatsudthipong V. Steviol retards renal cyst growth through reduction of CFTR expression and inhibition of epithelial cell proliferation in a mouse model of polycystic kidney disease. Biochemical Pharmacology. 88: 412-21. PMID 24518257 DOI: 10.1016/J.Bcp.2014.01.038 |
0.611 |
|
| 2014 |
Fedeles SV, Gallagher AR, Somlo S. Polycystin-1: a master regulator of intersecting cystic pathways. Trends in Molecular Medicine. 20: 251-60. PMID 24491980 DOI: 10.1016/J.Molmed.2014.01.004 |
0.658 |
|
| 2012 |
Fedeles S, Gallagher AR. Cell polarity and cystic kidney disease. Pediatric Nephrology (Berlin, Germany). 28: 1161-72. PMID 23161205 DOI: 10.1007/S00467-012-2337-Z |
0.347 |
|
| 2012 |
Lang S, Benedix J, Fedeles SV, Schorr S, Schirra C, Schäuble N, Jalal C, Greiner M, Hassdenteufel S, Tatzelt J, Kreutzer B, Edelmann L, Krause E, Rettig J, Somlo S, et al. Different effects of Sec61α, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. Journal of Cell Science. 125: 1958-69. PMID 22375059 DOI: 10.1242/Jcs.096727 |
0.574 |
|
| 2011 |
Fedeles SV, Tian X, Gallagher AR, Mitobe M, Nishio S, Lee SH, Cai Y, Geng L, Crews CM, Somlo S. A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nature Genetics. 43: 639-47. PMID 21685914 DOI: 10.1038/Ng.860 |
0.683 |
|
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