Sean W. Limesand, Ph.D. - Publications

Affiliations: 
2000 Colorado State University, Fort Collins, CO 
Area:
Animal Physiology Biology

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jackson IJ, Puttabytappa M, Anderson M, Muralidharan M, Veiga-Lopez A, Gregg B, Limesand S, Padmanabhan V. Developmental programming: Prenatal testosterone excess disrupts pancreatic islet developmental trajectory in female sheep. Molecular and Cellular Endocrinology. 110950. PMID 32726642 DOI: 10.1016/J.Mce.2020.110950  0.391
2020 Davis MA, Camacho LE, Anderson MJ, Steffens NR, Pendleton AL, Kelly AC, Limesand SW. Chronically Elevated Norepinephrine Concentrations Lower Glucose Uptake in Fetal Sheep. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 32667834 DOI: 10.1152/Ajpregu.00365.2019  0.368
2019 Yates DT, Camacho LE, Kelly AC, Steyn LV, Davis MA, Antolic AT, Anderson MJ, Goyal R, Allen RE, Papas KK, Hay WW, Limesand SW. Postnatal β2 Adrenergic Treatment Improves Insulin Sensitivity in Lambs with IUGR but not Persistent Defects in Pancreatic Islets or Skeletal Muscle. The Journal of Physiology. PMID 31665811 DOI: 10.1113/Jp278726  0.375
2019 Goyal D, Limesand SW, Goyal R. Epigenetic responses and the developmental origins of health and disease. The Journal of Endocrinology. 242: T105-T119. PMID 31091503 DOI: 10.1530/Joe-19-0009  0.317
2019 Jones AK, Rozance PJ, Brown LD, Goldstrohm DA, Hay WW, Limesand SW, Wesolowski SR. Sustained hypoxemia in late gestation potentiates hepatic gluconeogenic gene expression but does not activate glucose production in the ovine fetus. American Journal of Physiology. Endocrinology and Metabolism. PMID 30964701 DOI: 10.1152/Ajpendo.00069.2019  0.402
2018 Hart NJ, Weber C, Papas KK, Limesand SW, Vagner J, Lynch RM. Multivalent activation of GLP-1 and Sulfonylurea receptors modulates β-cell Second Messenger Signaling and Insulin Secretion. American Journal of Physiology. Cell Physiology. PMID 30404557 DOI: 10.1152/Ajpcell.00209.2018  0.363
2018 Kelly AC, Bidwell CA, Chen X, Macko AR, Anderson MJ, Limesand SW. Chronic Adrenergic Signaling Causes Abnormal RNA Expression of Proliferative Genes in Fetal Sheep Islets. Endocrinology. PMID 30124804 DOI: 10.1210/En.2018-00540  0.457
2018 Kelly AC, Smith KE, Purvis WG, Min CG, Weber CS, Cooksey AM, Hasilo C, Paraskevas S, Suszynski TM, Weegman BP, Anderson MJ, Camacho LE, Harland RC, Loudovaris T, Jandova J, ... ... Limesand SW, et al. Oxygen Perfusion (Persufflation) of Human Pancreata Enhances Insulin Secretion and Attenuates Islet Proinflammatory Signaling. Transplantation. PMID 30095738 DOI: 10.1097/Tp.0000000000002400  0.308
2018 Kelly AC, Camacho LE, Pendarvis K, Davenport HM, Steffens NR, Smith KE, Weber CS, Lynch RM, Papas KK, Limesand SW. Adrenergic receptor stimulation suppresses oxidative metabolism in isolated rat islets and Min6 cells. Molecular and Cellular Endocrinology. PMID 29360563 DOI: 10.1016/J.Mce.2018.01.012  0.376
2017 Boehmer BH, Limesand SW, Rozance PJ. The impact of IUGR on pancreatic islet development and β-cell function. The Journal of Endocrinology. PMID 28808079 DOI: 10.1530/Joe-17-0076  0.384
2017 Camacho LE, Chen X, Hay WW, Limesand SW. Enhanced insulin secretion and insulin sensitivity in young lambs with placental insufficiency-induced intrauterine growth restriction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00068.2017. PMID 28490449 DOI: 10.1152/Ajpregu.00068.2017  0.39
2017 Smith KE, Kelly AC, Min CG, Weber CS, McCarthy FM, Steyn LV, Badarinarayana V, Stanton JB, Kitzmann JP, Strop P, Gruessner AC, Lynch RM, Limesand SW, Papas KK. Acute Ischemia Induced by High Density Culture Increases Cytokine Expression and Diminishes the Function and Viability of Highly Purified Human Islets of Langerhans. Transplantation. PMID 28263224 DOI: 10.1097/Tp.0000000000001714  0.331
2017 Kelly AC, Bidwell CA, McCarthy FM, Taska DJ, Anderson MJ, Camacho LE, Limesand SW. RNA sequencing exposes novel adaptive and immune responses to intrauterine growth restriction in fetal sheep islets. Endocrinology. PMID 28200173 DOI: 10.1210/En.2016-1901  0.443
2017 Limesand SW, Rozance PJ. Fetal adaptations in insulin secretion result from high catecholamines during placental insufficiency. The Journal of Physiology. PMID 28194805 DOI: 10.1113/Jp273324  0.433
2017 Harris SE, De Blasio MJ, Davis MA, Kelly AC, Davenport HM, Wooding FB, Blache D, Meredith D, Anderson M, Fowden AL, Limesand SW, Forhead AJ. Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation. The Journal of Physiology. PMID 28144955 DOI: 10.1113/Jp273555  0.387
2017 Benjamin JS, Culpepper CB, Brown LD, Wesolowski SR, Jonker SS, Davis MA, Limesand SW, Wilkening RB, Hay WW, Rozance PJ. Chronic Anemic Hypoxemia Attenuates Glucose-Stimulated Insulin Secretion in Fetal Sheep. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00484.2016. PMID 28100476 DOI: 10.1152/Ajpregu.00484.2016  0.412
2017 Limesand SW. 737 Perinatal programming of pancreatic islets during intrauterine growth restriction Journal of Animal Science. 95: 358-358. DOI: 10.2527/Asasann.2017.737  0.304
2016 Chen X, Kelly AC, Yates DT, Macko AR, Lynch RM, Limesand SW. Islet adaptations in fetal sheep persist following chronic exposure to high norepinephrine. The Journal of Endocrinology. PMID 27888197 DOI: 10.1530/Joe-16-0445  0.408
2016 Brown LD, Davis M, Wai S, Wesolowski SR, Hay WW, Limesand SW, Rozance PJ. Chronically Increased Amino Acids Improve Insulin Secretion, Pancreatic Vascularity and Islet Size in Growth Restricted Fetal Sheep. Endocrinology. en20161328. PMID 27501184 DOI: 10.1210/En.2016-1328  0.378
2016 Hay WW, Brown LD, Rozance PJ, Wesolowski SR, Limesand SW. Challenges in Nourishing the IUGR Fetus-Lessons learned from studies in the IUGR fetal sheep. Acta Paediatrica (Oslo, Norway : 1992). PMID 27028695 DOI: 10.1111/Apa.13413  0.347
2016 Macko AR, Yates DT, Chen X, Shelton LA, Kelly AC, Davis MA, Camacho LE, Anderson MJ, Limesand SW. Adrenal Demedullation and Oxygen Supplementation Independently Increase Glucose-Stimulated Insulin Concentrations in Fetal Sheep with Intrauterine Growth Restriction. Endocrinology. en20151850. PMID 26937714 DOI: 10.1210/En.2015-1850  0.393
2015 Limesand SW. Insights Into the Progression of β-Cell Dysfunction Caused by Preterm Birth. Endocrinology. 156: 3494-5. PMID 26380938 DOI: 10.1210/En.2015-1723  0.38
2015 Davis MA, Macko AR, Steyn LV, Anderson MJ, Limesand SW. Fetal adrenal demedullation lowers circulating norepinephrine and attenuates growth restriction but not reduction of endocrine cell mass in an ovine model of intrauterine growth restriction. Nutrients. 7: 500-16. PMID 25584967 DOI: 10.3390/Nu7010500  0.336
2015 Andrews SE, Brown LD, Thorn SR, Limesand SW, Davis M, Hay WW, Rozance PJ. Increased adrenergic signaling is responsible for decreased glucose-stimulated insulin secretion in the chronically hyperinsulinemic ovine fetus. Endocrinology. 156: 367-76. PMID 25343274 DOI: 10.1210/En.2014-1393  0.415
2015 Rozance PJ, Anderson M, Martinez M, Fahy A, Macko AR, Kailey J, Seedorf GJ, Abman SH, Hay WW, Limesand SW. Placental insufficiency decreases pancreatic vascularity and disrupts hepatocyte growth factor signaling in the pancreatic islet endothelial cell in fetal sheep. Diabetes. 64: 555-64. PMID 25249573 DOI: 10.2337/Db14-0462  0.399
2015 Hill M, Kelly A, Reed K, Limesand S. 359: Fetal growth restriction and markers of metabolic dysfunction and inflammation American Journal of Obstetrics and Gynecology. 212: S188-S189. DOI: 10.1016/J.Ajog.2014.10.405  0.302
2014 Yates DT, Clarke DS, Macko AR, Anderson MJ, Shelton LA, Nearing M, Allen RE, Rhoads RP, Limesand SW. Myoblasts from intrauterine growth-restricted sheep fetuses exhibit intrinsic deficiencies in proliferation that contribute to smaller semitendinosus myofibres. The Journal of Physiology. 592: 3113-25. PMID 24860171 DOI: 10.1113/Jphysiol.2014.272591  0.324
2014 Kelly AC, Steyn LV, Kitzmann JP, Anderson MJ, Mueller KR, Hart NJ, Lynch RM, Papas KK, Limesand SW. Function and expression of sulfonylurea, adrenergic, and glucagon-like peptide 1 receptors in isolated porcine islets. Xenotransplantation. 21: 385-91. PMID 24801676 DOI: 10.1111/Xen.12101  0.345
2014 Hart NJ, Chung WJ, Weber C, Ananthakrishnan K, Anderson M, Patek R, Zhang Z, Limesand SW, Vagner J, Lynch RM. Hetero-bivalent GLP-1/glibenclamide for targeting pancreatic β-cells. Chembiochem : a European Journal of Chemical Biology. 15: 135-45. PMID 24259278 DOI: 10.1002/Cbic.201300375  0.305
2014 Chen X, Green AS, Macko AR, Yates DT, Kelly AC, Limesand SW. Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep. American Journal of Physiology. Endocrinology and Metabolism. 306: E58-64. PMID 24253046 DOI: 10.1152/Ajpendo.00517.2013  0.416
2013 Macko AR, Yates DT, Chen X, Green AS, Kelly AC, Brown LD, Limesand SW. Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation. Journal of Developmental Origins of Health and Disease. 4: 402-10. PMID 24358443 DOI: 10.1017/S2040174413000093  0.4
2013 Limesand SW, Rozance PJ, Macko AR, Anderson MJ, Kelly AC, Hay WW. Reductions in insulin concentrations and β-cell mass precede growth restriction in sheep fetuses with placental insufficiency. American Journal of Physiology. Endocrinology and Metabolism. 304: E516-23. PMID 23277186 DOI: 10.1152/Ajpendo.00435.2012  0.421
2013 Gadhia MM, Maliszewski AM, O'Meara MC, Thorn SR, Lavezzi JR, Limesand SW, Hay WW, Brown LD, Rozance PJ. Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep. American Journal of Physiology. Endocrinology and Metabolism. 304: E352-62. PMID 23211516 DOI: 10.1152/Ajpendo.00377.2012  0.381
2012 Frost MS, Zehri AH, Limesand SW, Hay WW, Rozance PJ. Differential effects of chronic pulsatile versus chronic constant maternal hyperglycemia on fetal pancreatic β-cells. Journal of Pregnancy. 2012: 812094. PMID 23133755 DOI: 10.1155/2012/812094  0.4
2012 Yates DT, Macko AR, Chen X, Green AS, Kelly AC, Anderson MJ, Fowden AL, Limesand SW. Hypoxaemia-induced catecholamine secretion from adrenal chromaffin cells inhibits glucose-stimulated hyperinsulinaemia in fetal sheep. The Journal of Physiology. 590: 5439-47. PMID 22907052 DOI: 10.1113/Jphysiol.2012.237347  0.316
2012 Yates DT, MacKo AR, Nearing M, Chen X, Rhoads RP, Limesand SW. Developmental programming in response to intrauterine growth restriction impairs myoblast function and skeletal muscle metabolism Journal of Pregnancy. 2012. PMID 22900186 DOI: 10.1155/2012/631038  0.347
2012 Chen X, Rozance PJ, Hay WW, Limesand SW. Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas. Experimental Biology and Medicine (Maywood, N.J.). 237: 524-9. PMID 22581814 DOI: 10.1258/Ebm.2012.011375  0.432
2012 Green AS, Chen X, Macko AR, Anderson MJ, Kelly AC, Hart NJ, Lynch RM, Limesand SW. Chronic pulsatile hyperglycemia reduces insulin secretion and increases accumulation of reactive oxygen species in fetal sheep islets. The Journal of Endocrinology. 212: 327-42. PMID 22182602 DOI: 10.1530/Joe-11-0300  0.392
2011 Yates DT, Löest CA, Ross TT, Hallford DM, Carter BH, Limesand SW. Effects of bacterial lipopolysaccharide injection on white blood cell counts, hematological variables, and serum glucose, insulin, and cortisol concentrations in ewes fed low- or high-protein diets. Journal of Animal Science. 89: 4286-93. PMID 21788428 DOI: 10.2527/Jas.2011-3969  0.301
2011 Yates DT, Green AS, Limesand SW. Catecholamines mediate multiple fetal adaptations during placental insufficiency that contribute to intrauterine growth restriction: lessons from hyperthermic sheep. Journal of Pregnancy. 2011: 740408. PMID 21773031 DOI: 10.1155/2011/740408  0.406
2011 Green AS, Macko AR, Rozance PJ, Yates DT, Chen X, Hay WW, Limesand SW. Characterization of glucose-insulin responsiveness and impact of fetal number and sex difference on insulin response in the sheep fetus. American Journal of Physiology. Endocrinology and Metabolism. 300: E817-23. PMID 21343544 DOI: 10.1152/Ajpendo.00572.2010  0.355
2011 Brown LD, Green AS, Limesand SW, Rozance PJ. Maternal amino acid supplementation for intrauterine growth restriction. Frontiers in Bioscience (Scholar Edition). 3: 428-44. PMID 21196387 DOI: 10.2741/S162  0.346
2011 Penrod L, Allen R, Rhoads M, Turner J, Limesand S, Arns M. Effects of Oxytocin, LPS, and Polyunsaturated Fatty Acids on PGF 2 α Secretion and Gene Expression during Equine Endometrial Culture Journal of Equine Veterinary Science. 31: 314. DOI: 10.1016/J.Jevs.2011.03.147  0.328
2010 Chen X, Fahy AL, Green AS, Anderson MJ, Rhoads RP, Limesand SW. β2-Adrenergic receptor desensitization in perirenal adipose tissue in fetuses and lambs with placental insufficiency-induced intrauterine growth restriction. The Journal of Physiology. 588: 3539-49. PMID 20643771 DOI: 10.1113/Jphysiol.2010.192310  0.341
2010 Green AS, Rozance PJ, Limesand SW. Consequences of a compromised intrauterine environment on islet function. The Journal of Endocrinology. 205: 211-24. PMID 20223861 DOI: 10.1677/Joe-09-0399  0.348
2010 Leos RA, Anderson MJ, Chen X, Pugmire J, Anderson KA, Limesand SW. Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction. American Journal of Physiology. Endocrinology and Metabolism. 298: E770-8. PMID 20086198 DOI: 10.1152/Ajpendo.00494.2009  0.408
2009 Cole L, Anderson M, Antin PB, Limesand SW. One process for pancreatic beta-cell coalescence into islets involves an epithelial-mesenchymal transition. The Journal of Endocrinology. 203: 19-31. PMID 19608613 DOI: 10.1677/Joe-09-0072  0.373
2009 Jeckel KM, Limesand SW, Anthony RV. Specificity protein-1 and -3 trans-activate the ovine placental lactogen gene promoter. Molecular and Cellular Endocrinology. 307: 118-24. PMID 19389461 DOI: 10.1016/J.Mce.2009.04.006  0.707
2009 Limesand SW, Rozance PJ, Brown LD, Hay WW. Effects of chronic hypoglycemia and euglycemic correction on lysine metabolism in fetal sheep. American Journal of Physiology. Endocrinology and Metabolism. 296: E879-87. PMID 19190258 DOI: 10.1152/Ajpendo.90832.2008  0.348
2009 Rozance PJ, Limesand SW, Barry JS, Brown LD, Hay WW. Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction. Pediatric Research. 65: 72-8. PMID 18704001 DOI: 10.1203/Pdr.0B013E318189358C  0.406
2008 Hiscox AM, Stone AL, Limesand S, Hoying JB, Williams SK. An islet-stabilizing implant constructed using a preformed vasculature. Tissue Engineering. Part A. 14: 433-40. PMID 18333795 DOI: 10.1089/Ten.2007.0099  0.359
2008 Rozance PJ, Limesand SW, Barry JS, Brown LD, Thorn SR, LoTurco D, Regnault TR, Friedman JE, Hay WW. Chronic late-gestation hypoglycemia upregulates hepatic PEPCK associated with increased PGC1alpha mRNA and phosphorylated CREB in fetal sheep. American Journal of Physiology. Endocrinology and Metabolism. 294: E365-70. PMID 18056789 DOI: 10.1152/Ajpendo.00639.2007  0.34
2007 Limesand SW, Rozance PJ, Smith D, Hay WW. Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction. American Journal of Physiology. Endocrinology and Metabolism. 293: E1716-25. PMID 17895285 DOI: 10.1152/Ajpendo.00459.2007  0.384
2007 Rozance PJ, Limesand SW, Zerbe GO, Hay WW. Chronic fetal hypoglycemia inhibits the later steps of stimulus-secretion coupling in pancreatic beta-cells. American Journal of Physiology. Endocrinology and Metabolism. 292: E1256-64. PMID 17213478 DOI: 10.1152/Ajpendo.00265.2006  0.395
2007 Leos R, Anderson M, Cole L, Limesand S. CATECHOLAMINES INHIBIT INSULIN SECRETION IN SHEEP FETUSES WITH PLACENTAL INSUFFICIENCY AND INTRAUTERINE GROWTH RESTRICTION Biology of Reproduction. 77: 126-126. DOI: 10.1093/Biolreprod/77.S1.126B  0.397
2006 Barry JS, Davidsen ML, Limesand SW, Galan HL, Friedman JE, Regnault TR, Hay WW. Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction. Experimental Biology and Medicine (Maywood, N.J.). 231: 566-75. PMID 16636305 DOI: 10.1177/153537020623100511  0.367
2006 Rozance PJ, Limesand SW, Hay WW. Decreased nutrient-stimulated insulin secretion in chronically hypoglycemic late-gestation fetal sheep is due to an intrinsic islet defect. American Journal of Physiology. Endocrinology and Metabolism. 291: E404-11. PMID 16569758 DOI: 10.1152/Ajpendo.00643.2005  0.395
2006 Limesand SW, Rozance PJ, Zerbe GO, Hutton JC, Hay WW. Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction. Endocrinology. 147: 1488-97. PMID 16339204 DOI: 10.1210/En.2005-0900  0.383
2005 Wallace JM, Regnault TR, Limesand SW, Hay WW, Anthony RV. Investigating the causes of low birth weight in contrasting ovine paradigms. The Journal of Physiology. 565: 19-26. PMID 15774527 DOI: 10.1113/Jphysiol.2004.082032  0.628
2005 Limesand SW, Jensen J, Hutton JC, Hay WW. Diminished beta-cell replication contributes to reduced beta-cell mass in fetal sheep with intrauterine growth restriction. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 288: R1297-305. PMID 15650129 DOI: 10.1152/Ajpregu.00494.2004  0.34
2004 Wooding FB, Fowden AL, Bell AW, Ehrhardt RA, Limesand SW, Hay WW. Localisation of glucose transport in the ruminant placenta: implications for sequential use of transporter isoforms. Placenta. 26: 626-40. PMID 16085042 DOI: 10.1016/J.Placenta.2004.09.013  0.315
2004 Limesand SW, Regnault TR, Hay WW. Characterization of glucose transporter 8 (GLUT8) in the ovine placenta of normal and growth restricted fetuses. Placenta. 25: 70-7. PMID 15013641 DOI: 10.1016/J.Placenta.2003.08.012  0.382
2004 Limesand SW, Jeckel KM, Anthony RV. Puralpha, a single-stranded deoxyribonucleic acid binding protein, augments placental lactogen gene transcription. Molecular Endocrinology (Baltimore, Md.). 18: 447-57. PMID 14645500 DOI: 10.1210/Me.2003-0392  0.714
2003 Limesand SW, Hay WW. Adaptation of ovine fetal pancreatic insulin secretion to chronic hypoglycaemia and euglycaemic correction. The Journal of Physiology. 547: 95-105. PMID 12562941 DOI: 10.1111/J.1469-7793.2003.00095.X  0.373
2003 Padoan A, Regnault TR, DeVrijer B, Limesand SW, Anthony RV, Ferrazzi E, Wilkening RB, Galan HL. Endothelial nitric oxide synthase in uteroplacental vasculature in an ovine model of IUGR American Journal of Obstetrics and Gynecology. 189: S193. DOI: 10.1016/J.Ajog.2003.10.491  0.548
2001 Anthony RV, Limesand SW, Jeckel KM. Transcriptional regulation in the placenta during normal and compromised fetal growth. Biochemical Society Transactions. 29: 42-8. PMID 11356124 DOI: 10.1042/Bst0290042  0.722
2001 Limesand SW, Anthony RV. Novel activator protein-2alpha splice-variants function as transactivators of the ovine placental lactogen gene. European Journal of Biochemistry / Febs. 268: 2390-401. PMID 11298758 DOI: 10.1046/J.1432-1327.2001.02124.X  0.593
2001 Regnault TRH, Limesand SW, Hay WW. Factors Influencing Fetal Growth Neoreviews. 2: 119e-128. DOI: 10.1542/Neo.2-6-E119  0.398
1999 Liang R, Limesand SW, Anthony RV. Structure and transcriptional regulation of the ovine placental lactogen gene. European Journal of Biochemistry / Febs. 265: 883-95. PMID 10518781 DOI: 10.1046/J.1432-1327.1999.00790.X  0.632
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