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Karen Marie Vasquez, Ph.D. - Publications

Affiliations: 
Pharmacology & Toxicology University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
DNA damage and repair, genomic instability, gene targeting, DNA structure, cancer therapeutics Current Research
Website:
http://www.utexas.edu/pharmacy/divisions/pharmtox/faculty/vasquez.html

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang G, Christensen L, Vasquez KM. Methods to Study Z-DNA-Induced Genetic Instability. Methods in Molecular Biology (Clifton, N.J.). 2651: 227-240. PMID 36892771 DOI: 10.1007/978-1-0716-3084-6_16  0.472
2022 Wang G, Vasquez KM. Dynamic alternative DNA structures in biology and disease. Nature Reviews. Genetics. PMID 36316397 DOI: 10.1038/s41576-022-00539-9  0.466
2022 Meng Y, Wang G, He H, Lau KH, Hurt A, Bixler BJ, Parham A, Jin SG, Xu X, Vasquez KM, Pfeifer GP, Szabó PE. Z-DNA is remodelled by ZBTB43 in prospermatogonia to safeguard the germline genome and epigenome. Nature Cell Biology. PMID 35787683 DOI: 10.1038/s41556-022-00941-9  0.492
2021 Balana AT, Mukherjee A, Nagpal H, Moon SP, Fierz B, Vasquez KM, Pratt MR. O-GlcNAcylation of High Mobility Group Box 1 (HMGB1) Alters Its DNA Binding and DNA Damage Processing Activities. Journal of the American Chemical Society. PMID 34546745 DOI: 10.1021/jacs.1c06192  0.419
2021 Herbert A, Karapetyan S, Poptsova M, Vasquez KM, Vicens Q, Vögeli B. Special Issue: A, B and Z: The Structure, Function and Genetics of Z-DNA and Z-RNA. International Journal of Molecular Sciences. 22. PMID 34299306 DOI: 10.3390/ijms22147686  0.321
2021 Herbert A, Wang AH, Jovin TM, Mocarski ES, Pasparakis M, Vasquez KM. Concern over use of the term Z-DNA. Nature. 594: 333. PMID 34131341 DOI: 10.1038/d41586-021-01595-7  0.337
2021 Herbert A, Wang AH, Jovin TM, Mocarski ES, Pasparakis M, Vasquez KM. Concern over use of the term Z-DNA. Nature. 594: 333. PMID 34131341 DOI: 10.1038/d41586-021-01595-7  0.337
2021 D'Amico AM, Vasquez KM. The multifaceted roles of DNA repair and replication proteins in aging and obesity. Dna Repair. 99: 103049. PMID 33529944 DOI: 10.1016/j.dnarep.2021.103049  0.355
2020 Barwal TS, Sharma U, Vasquez KM, Prakash H, Jain A. A panel of circulating long non-coding RNAs as liquid biopsy biomarkers for breast and cervical cancers. Biochimie. 176: 62-70. PMID 32634463 DOI: 10.1016/J.Biochi.2020.06.012  0.316
2020 Sharma U, Barwal TS, Malhotra A, Pant N, Vivek, Dey D, Gautam A, Tuli HS, Vasquez KM, Jain A. Long non-coding RNA TINCR as potential biomarker and therapeutic target for cancer. Life Sciences. 118035. PMID 32622950 DOI: 10.1016/J.Lfs.2020.118035  0.301
2020 McKinney JA, Wang G, Vasquez KM. Distinct mechanisms of mutagenic processing of alternative DNA structures by repair proteins. Molecular & Cellular Oncology. 7: 1743807. PMID 32391433 DOI: 10.1080/23723556.2020.1743807  0.559
2020 Mukherjee A, Vasquez KM. Targeting chromosomal architectural HMGB proteins could be the next frontier in cancer therapy. Cancer Research. PMID 32152151 DOI: 10.1158/0008-5472.Can-19-3066  0.516
2020 Del Mundo IMA, Cho EJ, Dalby KN, Vasquez KM. A 'light-up' intercalator displacement assay for detection of triplex DNA stabilizers. Chemical Communications (Cambridge, England). PMID 31960843 DOI: 10.1039/C9Cc08817B  0.499
2020 McKinney JA, Wang G, Mukherjee A, Christensen L, Subramanian SHS, Zhao J, Vasquez KM. Distinct DNA repair pathways cause genomic instability at alternative DNA structures. Nature Communications. 11: 236. PMID 31932649 DOI: 10.1038/S41467-019-13878-9  0.584
2019 Tamang S, Acharya V, Roy D, Sharma R, Aryaa A, Sharma U, Khandelwal A, Prakash H, Vasquez KM, Jain A. SNHG12: An LncRNA as a Potential Therapeutic Target and Biomarker for Human Cancer. Frontiers in Oncology. 9: 901. PMID 31620362 DOI: 10.3389/Fonc.2019.00901  0.315
2019 Mandke P, Vasquez KM. Interactions of high mobility group box protein 1 (HMGB1) with nucleic acids: Implications in DNA repair and immune responses. Dna Repair. 83: 102701. PMID 31563843 DOI: 10.1016/J.Dnarep.2019.102701  0.527
2019 Del Mundo IMA, Vasquez KM, Wang G. Modulation of DNA structure formation using small molecules. Biochimica Et Biophysica Acta. Molecular Cell Research. 118539. PMID 31491448 DOI: 10.1016/J.Bbamcr.2019.118539  0.56
2019 Mukherjee A, Huynh V, Gaines K, Reh WA, Vasquez KM. Targeting the High Mobility Group Box 3 protein sensitizes chemoresistant ovarian cancer cells to cisplatin. Cancer Research. PMID 31061066 DOI: 10.1158/0008-5472.Can-19-0542  0.405
2019 Del Mundo IMA, Cho EJ, Dalby KN, Vasquez KM. A tunable assay for modulators of genome-destabilizing DNA structures. Nucleic Acids Research. PMID 30949695 DOI: 10.1093/Nar/Gkz237  0.555
2019 Xie KT, Wang G, Thompson AC, Wucherpfennig JI, Reimchen TE, MacColl ADC, Schluter D, Bell MA, Vasquez KM, Kingsley DM. DNA fragility in the parallel evolution of pelvic reduction in stickleback fish. Science (New York, N.Y.). 363: 81-84. PMID 30606845 DOI: 10.1126/Science.Aan1425  0.531
2018 Jain A, Wang G, Vasquez KM. Corrigendum to "DNA Triple Helices: Biological consequences and therapeutic potential" [Biochimie 90/8 (2008) 1117-1130]. Biochimie. PMID 29580585 DOI: 10.1016/J.Biochi.2018.03.004  0.52
2018 Zhao J, Wang G, Del Mundo IM, McKinney JA, Lu X, Bacolla A, Boulware SB, Zhang C, Zhang H, Ren P, Freudenreich CH, Vasquez KM. Distinct Mechanisms of Nuclease-Directed DNA-Structure-Induced Genetic Instability in Cancer Genomes. Cell Reports. 22: 1200-1210. PMID 29386108 DOI: 10.1016/J.Celrep.2018.01.014  0.56
2018 Mukherjee A, Reh WA, Vasquez KM. Abstract 1375: High mobility group box proteins modulate chemotherapeutic DNA damage repair processing in human cells Cancer Research. 78: 1375-1375. DOI: 10.1158/1538-7445.Am2018-1375  0.55
2017 Del Mundo IM, Zewail-Foote M, Kerwin SM, Vasquez KM. Alternative DNA structure formation in the mutagenic human c-MYC promoter. Nucleic Acids Research. PMID 28334873 DOI: 10.1093/Nar/Gkx100  0.548
2017 Wang G, Vasquez KM. Effects of Replication and Transcription on DNA Structure-Related Genetic Instability. Genes. 8. PMID 28067787 DOI: 10.3390/Genes8010017  0.553
2016 Reh WA, Nairn RS, Lowery MP, Vasquez KM. The homologous recombination protein RAD51D protects the genome from large deletions. Nucleic Acids Research. PMID 27924006 DOI: 10.1093/Nar/Gkw1204  0.47
2016 Mukherjee A, Vasquez KM. Tools to Study the Role of Architectural Protein HMGB1 in the Processing of Helix Distorting, Site-specific DNA Interstrand Crosslinks. Journal of Visualized Experiments : Jove. PMID 27911399 DOI: 10.3791/54678  0.602
2016 Wang G, Zhao J, Vasquez KM. Detection of cis- and trans-acting Factors in DNA Structure-Induced Genetic Instability Using In silico and Cellular Approaches. Frontiers in Genetics. 7: 135. PMID 27532010 DOI: 10.3389/Fgene.2016.00135  0.543
2016 Bacolla A, Tainer JA, Vasquez KM, Cooper DN. Translocation and deletion breakpoints in cancer genomes are associated with potential non-B DNA-forming sequences. Nucleic Acids Research. PMID 27084947 DOI: 10.1093/Nar/Gkw261  0.531
2015 Bacolla A, Wang G, Vasquez KM. New Perspectives on DNA and RNA Triplexes As Effectors of Biological Activity. Plos Genetics. 11: e1005696. PMID 26700634 DOI: 10.1371/Journal.Pgen.1005696  0.43
2015 Mukherjee A, Vasquez KM. HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells. Nucleic Acids Research. PMID 26578599 DOI: 10.1093/Nar/Gkv1183  0.505
2015 Temiz NA, Donohue DE, Bacolla A, Vasquez KM, Cooper DN, Mudunuri U, Ivanic J, Cer RZ, Yi M, Stephens RM, Collins JR, Luke BT. The somatic autosomal mutation matrix in cancer genomes. Human Genetics. 134: 851-64. PMID 26001532 DOI: 10.1007/S00439-015-1566-1  0.375
2015 Bacolla A, Zhu X, Chen H, Howells K, Cooper DN, Vasquez KM. Local DNA dynamics shape mutational patterns of mononucleotide repeats in human genomes. Nucleic Acids Research. 43: 5065-80. PMID 25897114 DOI: 10.1093/Nar/Gkv364  0.479
2015 Lu S, Wang G, Bacolla A, Zhao J, Spitser S, Vasquez KM. Short Inverted Repeats Are Hotspots for Genetic Instability: Relevance to Cancer Genomes. Cell Reports. PMID 25772355 DOI: 10.1016/J.Celrep.2015.02.039  0.488
2014 Wang G, Vasquez KM. Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability. Dna Repair. 19: 143-51. PMID 24767258 DOI: 10.1016/J.Dnarep.2014.03.017  0.558
2014 Bacolla A, Cooper DN, Vasquez KM. Mechanisms of base substitution mutagenesis in cancer genomes. Genes. 5: 108-46. PMID 24705290 DOI: 10.3390/Genes5010108  0.533
2014 Boulware SB, Christensen LA, Thames H, Coghlan L, Vasquez KM, Finch RA. Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer. Molecular Carcinogenesis. 53: 744-52. PMID 23681918 DOI: 10.1002/Mc.22026  0.486
2013 Bacolla A, Temiz NA, Yi M, Ivanic J, Cer RZ, Donohue DE, Ball EV, Mudunuri US, Wang G, Jain A, Volfovsky N, Luke BT, Stephens RM, Cooper DN, Collins JR, ... Vasquez KM, et al. Guanine holes are prominent targets for mutation in cancer and inherited disease. Plos Genetics. 9: e1003816. PMID 24086153 DOI: 10.1371/Journal.Pgen.1003816  0.444
2013 Jain A, Bacolla A, Del Mundo IM, Zhao J, Wang G, Vasquez KM. DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells. Nucleic Acids Research. 41: 10345-57. PMID 24049074 DOI: 10.1093/Nar/Gkt804  0.556
2013 Wang G, Gaddis S, Vasquez KM. Methods to detect replication-dependent and replication-independent DNA structure-induced genetic instability. Methods (San Diego, Calif.). 64: 67-72. PMID 23954565 DOI: 10.1016/J.Ymeth.2013.08.004  0.547
2013 Bacolla A, Cooper DN, Vasquez KM. DNA structure matters. Genome Medicine. 5: 51. PMID 23796271 DOI: 10.1186/Gm455  0.48
2013 Wang Y, Leung JW, Jiang Y, Lowery MG, Do H, Vasquez KM, Chen J, Wang W, Li L. FANCM and FAAP24 maintain genome stability via cooperative as well as unique functions. Molecular Cell. 49: 997-1009. PMID 23333308 DOI: 10.1016/J.Molcel.2012.12.010  0.527
2013 Vasquez KM, Wang G. The yin and yang of repair mechanisms in DNA structure-induced genetic instability. Mutation Research. 743: 118-31. PMID 23219604 DOI: 10.1016/J.Mrfmmm.2012.11.005  0.554
2013 Wang G, Christensen LA, Vasquez KM. 118 DNA structure-induced genetic instability in mammals Journal of Biomolecular Structure and Dynamics. 31: 75-75. DOI: 10.1080/07391102.2013.786360  0.57
2013 Wang G, Christensen LA, Spitser SA, Vasquez KM. 117 Non-B DNA structure-induced genetic instability in mammalian cells Journal of Biomolecular Structure and Dynamics. 31: 74-75. DOI: 10.1080/07391102.2013.786359  0.565
2012 Wojcik EA, Brzostek A, Bacolla A, Mackiewicz P, Vasquez KM, Korycka-Machala M, Jaworski A, Dziadek J. Direct and inverted repeats elicit genetic instability by both exploiting and eluding DNA double-strand break repair systems in mycobacteria. Plos One. 7: e51064. PMID 23251422 DOI: 10.1371/Journal.Pone.0051064  0.561
2012 Boulware S, Fields T, McIvor E, Powell KL, Abel EL, Vasquez KM, MacLeod MC. 2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog. Toxicology and Applied Pharmacology. 263: 203-9. PMID 22732900 DOI: 10.1016/J.Taap.2012.06.010  0.346
2011 Cooper DN, Bacolla A, Férec C, Vasquez KM, Kehrer-Sawatzki H, Chen JM. On the sequence-directed nature of human gene mutation: the role of genomic architecture and the local DNA sequence environment in mediating gene mutations underlying human inherited disease. Human Mutation. 32: 1075-99. PMID 21853507 DOI: 10.1002/Humu.21557  0.517
2011 Mukherjee A, Vasquez KM. Triplex technology in studies of DNA damage, DNA repair, and mutagenesis. Biochimie. 93: 1197-208. PMID 21501652 DOI: 10.1016/J.Biochi.2011.04.001  0.582
2011 Bacolla A, Wang G, Jain A, Chuzhanova NA, Cer RZ, Collins JR, Cooper DN, Bohr VA, Vasquez KM. Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells. The Journal of Biological Chemistry. 286: 10017-26. PMID 21285356 DOI: 10.1074/Jbc.M110.176636  0.521
2011 Lu S, Wang G, Vasquez KM. Abstract 2732: Short inverted repeats are hot spots for genetic instability in mammalian cells Cancer Research. 71: 2732-2732. DOI: 10.1158/1538-7445.Am2011-2732  0.549
2010 Jain A, Bacolla A, Chakraborty P, Grosse F, Vasquez KM. Human DHX9 helicase unwinds triple-helical DNA structures. Biochemistry. 49: 6992-9. PMID 20669935 DOI: 10.1021/Bi100795M  0.57
2010 Vasquez KM, Legerski RJ. DNA interstrand crosslinks: repair, cell signaling, and therapeutic implications. Environmental and Molecular Mutagenesis. 51: 491-2. PMID 20577999 DOI: 10.1002/Em.20598  0.487
2010 Kha DT, Wang G, Natrajan N, Harrison L, Vasquez KM. Pathways for double-strand break repair in genetically unstable Z-DNA-forming sequences. Journal of Molecular Biology. 398: 471-80. PMID 20347845 DOI: 10.1016/J.Jmb.2010.03.035  0.565
2010 Vasquez KM. Targeting and processing of site-specific DNA interstrand crosslinks. Environmental and Molecular Mutagenesis. 51: 527-39. PMID 20196133 DOI: 10.1002/Em.20557  0.543
2010 Powell KL, Boulware S, Thames H, Vasquez KM, MacLeod MC. 2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide. Chemical Research in Toxicology. 23: 497-503. PMID 20050631 DOI: 10.1021/Tx9001918  0.379
2010 Zhao J, Bacolla A, Wang G, Vasquez KM. Non-B DNA structure-induced genetic instability and evolution. Cellular and Molecular Life Sciences : Cmls. 67: 43-62. PMID 19727556 DOI: 10.1007/S00018-009-0131-2  0.54
2009 Liu Y, Nairn RS, Vasquez KM. Targeted gene conversion induced by triplex-directed psoralen interstrand crosslinks in mammalian cells. Nucleic Acids Research. 37: 6378-88. PMID 19726585 DOI: 10.1093/Nar/Gkp678  0.475
2009 Kolb J, Chuzhanova NA, Högel J, Vasquez KM, Cooper DN, Bacolla A, Kehrer-Sawatzki H. Cruciform-forming inverted repeats appear to have mediated many of the microinversions that distinguish the human and chimpanzee genomes. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 17: 469-83. PMID 19475482 DOI: 10.1007/S10577-009-9039-9  0.511
2009 Zhao J, Jain A, Iyer RR, Modrich PL, Vasquez KM. Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks. Nucleic Acids Research. 37: 4420-9. PMID 19468048 DOI: 10.1093/Nar/Gkp399  0.531
2009 Lange SS, Reddy MC, Vasquez KM. Human HMGB1 directly facilitates interactions between nucleotide excision repair proteins on triplex-directed psoralen interstrand crosslinks. Dna Repair. 8: 865-72. PMID 19446504 DOI: 10.1016/J.Dnarep.2009.04.001  0.492
2009 Lange SS, Vasquez KM. HMGB1: the jack-of-all-trades protein is a master DNA repair mechanic. Molecular Carcinogenesis. 48: 571-80. PMID 19360789 DOI: 10.1002/Mc.20544  0.526
2009 Vasquez KM, Hanawalt PC. Intrinsic genomic instability from naturally occurring DNA structures: An introduction to the special issue. Molecular Carcinogenesis. 48: 271-2. PMID 19306307 DOI: 10.1002/Mc.20519  0.479
2009 Wang G, Zhao J, Vasquez KM. Methods to determine DNA structural alterations and genetic instability. Methods (San Diego, Calif.). 48: 54-62. PMID 19245837 DOI: 10.1016/J.Ymeth.2009.02.012  0.508
2009 Wang G, Vasquez KM. Models for chromosomal replication-independent non-B DNA structure-induced genetic instability. Molecular Carcinogenesis. 48: 286-98. PMID 19123200 DOI: 10.1002/Mc.20508  0.534
2009 Bétous R, Rey L, Wang G, Pillaire MJ, Puget N, Selves J, Biard DS, Shin-ya K, Vasquez KM, Cazaux C, Hoffmann JS. Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. Molecular Carcinogenesis. 48: 369-78. PMID 19117014 DOI: 10.1002/Mc.20509  0.575
2008 Wang G, Carbajal S, Vijg J, DiGiovanni J, Vasquez KM. DNA structure-induced genomic instability in vivo. Journal of the National Cancer Institute. 100: 1815-7. PMID 19066276 DOI: 10.1093/Jnci/Djn385  0.527
2008 Christensen LA, Wang H, Van Houten B, Vasquez KM. Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease. Nucleic Acids Research. 36: 7136-45. PMID 18996898 DOI: 10.1093/Nar/Gkn880  0.549
2008 Wu Q, Vasquez KM. Human MLH1 protein participates in genomic damage checkpoint signaling in response to DNA interstrand crosslinks, while MSH2 functions in DNA repair. Plos Genetics. 4: e1000189. PMID 18787700 DOI: 10.1371/Journal.Pgen.1000189  0.509
2008 Lange SS, Mitchell DL, Vasquez KM. High mobility group protein B1 enhances DNA repair and chromatin modification after DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 105: 10320-5. PMID 18650382 DOI: 10.1073/Pnas.0803181105  0.548
2008 Liu Y, Nairn RS, Vasquez KM. Processing of triplex-directed psoralen DNA interstrand crosslinks by recombination mechanisms. Nucleic Acids Research. 36: 4680-8. PMID 18628293 DOI: 10.1093/Nar/Gkn438  0.471
2008 Benfield AP, Macleod MC, Liu Y, Wu Q, Wensel TG, Vasquez KM. Targeted generation of DNA strand breaks using pyrene-conjugated triplex-forming oligonucleotides. Biochemistry. 47: 6279-88. PMID 18473480 DOI: 10.1021/Bi7024029  0.729
2008 Ditlevson JV, Tornaletti S, Belotserkovskii BP, Teijeiro V, Wang G, Vasquez KM, Hanawalt PC. Inhibitory effect of a short Z-DNA forming sequence on transcription elongation by T7 RNA polymerase. Nucleic Acids Research. 36: 3163-70. PMID 18400779 DOI: 10.1093/Nar/Gkn136  0.479
2008 Jain A, Wang G, Vasquez KM. DNA triple helices: biological consequences and therapeutic potential. Biochimie. 90: 1117-30. PMID 18331847 DOI: 10.1016/J.Biochi.2008.02.011  0.592
2007 Belotserkovskii BP, De Silva E, Tornaletti S, Wang G, Vasquez KM, Hanawalt PC. A triplex-forming sequence from the human c-MYC promoter interferes with DNA transcription. The Journal of Biological Chemistry. 282: 32433-41. PMID 17785457 DOI: 10.1074/Jbc.M704618200  0.483
2007 Wang G, Vasquez KM. Z-DNA, an active element in the genome. Frontiers in Bioscience : a Journal and Virtual Library. 12: 4424-38. PMID 17485386 DOI: 10.2741/2399  0.572
2007 Wu Q, Gaddis SS, MacLeod MC, Walborg EF, Thames HD, DiGiovanni J, Vasquez KM. High-affinity triplex-forming oligonucleotide target sequences in mammalian genomes. Molecular Carcinogenesis. 46: 15-23. PMID 17013831 DOI: 10.1002/Mc.20261  0.449
2006 Gaddis SS, Wu Q, Thames HD, DiGiovanni J, Walborg EF, MacLeod MC, Vasquez KM. A web-based search engine for triplex-forming oligonucleotide target sequences. Oligonucleotides. 16: 196-201. PMID 16764543 DOI: 10.1089/Oli.2006.16.196  0.537
2006 Christensen LA, Finch RA, Booker AJ, Vasquez KM. Targeting oncogenes to improve breast cancer chemotherapy. Cancer Research. 66: 4089-94. PMID 16618728 DOI: 10.1158/0008-5472.Can-05-4288  0.42
2006 Wang G, Vasquez KM. Non-B DNA structure-induced genetic instability. Mutation Research. 598: 103-19. PMID 16516932 DOI: 10.1016/J.Mrfmmm.2006.01.019  0.559
2006 Wang G, Christensen LA, Vasquez KM. Z-DNA-forming sequences generate large-scale deletions in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 2677-82. PMID 16473937 DOI: 10.1073/Pnas.0511084103  0.559
2005 Reddy MC, Vasquez KM. Repair of genome destabilizing lesions. Radiation Research. 164: 345-56. PMID 16187737 DOI: 10.1667/Rr3419.1  0.558
2005 Lu X, Zhang N, Vasquez K, Barton M, Legerski R. Repair of psoralen interstrand cross-links in Xenopus laevis egg extracts is highly mutagenic Biochemical and Biophysical Research Communications. 336: 69-75. PMID 16125670 DOI: 10.1016/J.Bbrc.2005.08.042  0.343
2005 Thoma BS, Wakasugi M, Christensen J, Reddy MC, Vasquez KM. Human XPC-hHR23B interacts with XPA-RPA in the recognition of triplex-directed psoralen DNA interstrand crosslinks. Nucleic Acids Research. 33: 2993-3001. PMID 15914671 DOI: 10.1093/Nar/Gki610  0.572
2005 Wu Q, Christensen LA, Legerski RJ, Vasquez KM. Mismatch repair participates in error-free processing of DNA interstrand crosslinks in human cells. Embo Reports. 6: 551-7. PMID 15891767 DOI: 10.1038/Sj.Embor.7400418  0.489
2005 Reddy MC, Christensen J, Vasquez KM. Interplay between human high mobility group protein 1 and replication protein A on psoralen-cross-linked DNA. Biochemistry. 44: 4188-95. PMID 15766246 DOI: 10.1021/Bi047902N  0.535
2004 Wang G, Vasquez KM. Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 13448-53. PMID 15342911 DOI: 10.1073/Pnas.0405116101  0.553
2004 Christensen LA, Conti CJ, Fischer SM, Vasquez KM. Mutation frequencies in murine keratinocytes as a function of carcinogenic status. Molecular Carcinogenesis. 40: 122-33. PMID 15170817 DOI: 10.1002/Mc.20026  0.358
2003 Thoma BS, Vasquez KM. Critical DNA damage recognition functions of XPC-hHR23B and XPA-RPA in nucleotide excision repair. Molecular Carcinogenesis. 38: 1-13. PMID 12949838 DOI: 10.1002/Mc.10143  0.543
2002 Rogers FA, Vasquez KM, Egholm M, Glazer PM. Site-directed recombination via bifunctional PNA-DNA conjugates. Proceedings of the National Academy of Sciences of the United States of America. 99: 16695-700. PMID 12461167 DOI: 10.1073/Pnas.262556899  0.613
2002 Vasquez KM, Glazer PM. Triplex-forming oligonucleotides: principles and applications. Quarterly Reviews of Biophysics. 35: 89-107. PMID 11997982 DOI: 10.1017/S0033583502003773  0.422
2002 Vasquez KM, Christensen J, Li L, Finch RA, Glazer PM. Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proceedings of the National Academy of Sciences of the United States of America. 99: 5848-53. PMID 11972036 DOI: 10.1073/Pnas.082193799  0.567
2001 Vasquez KM, Dagle JM, Weeks DL, Glazer PM. Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides. The Journal of Biological Chemistry. 276: 38536-41. PMID 11504712 DOI: 10.1074/Jbc.M101797200  0.436
2001 Vasquez KM, Marburger K, Intody Z, Wilson JH. Manipulating the mammalian genome by homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 98: 8403-10. PMID 11459982 DOI: 10.1073/Pnas.111009698  0.537
2001 Datta HJ, Chan PP, Vasquez KM, Gupta RC, Glazer PM. Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51. The Journal of Biological Chemistry. 276: 18018-23. PMID 11278954 DOI: 10.1074/Jbc.M011646200  0.476
2000 Vasquez KM, Narayanan L, Glazer PM. Specific mutations induced by triplex-forming oligonucleotides in mice. Science (New York, N.Y.). 290: 530-3. PMID 11039937 DOI: 10.1126/Science.290.5491.530  0.419
2000 Finch RA, Liu M, Grill SP, Rose WC, Loomis R, Vasquez KM, Cheng Y, Sartorelli AC. Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity. Biochemical Pharmacology. 59: 983-91. PMID 10692563 DOI: 10.1016/S0006-2952(99)00419-0  0.434
2000 Vasquez KM, Wilson JH. Triplex-directed site-specific genome modification. Methods in Molecular Biology (Clifton, N.J.). 133: 183-200. PMID 10561839 DOI: 10.1385/1-59259-215-5:183  0.344
1999 Perkins BD, Wensel TG, Vasquez KM, Wilson JH. Psoralen photo-cross-linking by triplex-forming oligonucleotides at multiple sites in the human rhodopsin gene. Biochemistry. 38: 12850-9. PMID 10504255 DOI: 10.1021/Bi9902743  0.758
1999 Vasquez KM, Wang G, Havre PA, Glazer PM. Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells. Nucleic Acids Research. 27: 1176-81. PMID 9927753 DOI: 10.1093/Nar/27.4.1176  0.43
1998 Perkins BD, Wilson JH, Wensel TG, Vasquez KM. Triplex targets in the human rhodopsin gene. Biochemistry. 37: 11315-22. PMID 9698379 DOI: 10.1021/Bi980525S  0.717
1998 Vasquez KM, Wilson JH. Triplex-directed modification of genes and gene activity. Trends in Biochemical Sciences. 23: 4-9. PMID 9478127 DOI: 10.1016/S0968-0004(97)01158-4  0.462
1996 Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-efficiency triple-helix-mediated photo-cross-linking at a targeted site within a selectable mammalian gene. Biochemistry. 35: 10712-9. PMID 8718860 DOI: 10.1021/Bi960881F  0.66
1995 Vasquez KM, Wensel TG, Hogan ME, Wilson JH. High-affinity triple helix formation by synthetic oligonucleotides at a site within a selectable mammalian gene. Biochemistry. 34: 7243-51. PMID 7766635 DOI: 10.1021/Bi00021A040  0.678
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