| Year |
Citation |
Score |
| 2022 |
Leite NC, Pelayo GC, Melton DA. Genetic manipulation of stress pathways can protect stem-cell-derived islets from apoptosis in vitro. Stem Cell Reports. 17: 766-774. PMID 35245439 DOI: 10.1016/j.stemcr.2022.01.018 |
0.314 |
|
| 2021 |
Gerace D, Kenty JH, Melton DA. 209.2: Engineering Immune-evasive Human Stem Cell-derived Islet Cells. Transplantation. 105: S13. PMID 34908313 DOI: 10.1097/01.tp.0000804344.89342.14 |
0.32 |
|
| 2021 |
Sintov E, Gerace D, Melton DA. A human ESC line for efficient CRISPR editing of pluripotent stem cells. Stem Cell Research. 57: 102591. PMID 34741877 DOI: 10.1016/j.scr.2021.102591 |
0.421 |
|
| 2021 |
Gerace D, Boulanger KR, Hyoje-Ryu Kenty J, Melton DA. Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny. Stem Cell Research. 53: 102371. PMID 34088000 DOI: 10.1016/j.scr.2021.102371 |
0.419 |
|
| 2020 |
Cai EP, Ishikawa Y, Zhang W, Leite NC, Li J, Hou S, Kiaf B, Hollister-Lock J, Yilmaz NK, Schiffer CA, Melton DA, Kissler S, Yi P. Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes. Nature Metabolism. PMID 32719542 DOI: 10.1038/s42255-020-0254-1 |
0.538 |
|
| 2020 |
Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA. Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Reports. 32: 107894. PMID 32668238 DOI: 10.1016/j.celrep.2020.107894 |
0.479 |
|
| 2020 |
Rasouli N, Melton DA, Alvarez-Dominguez JR. Purification of Live Stem-Cell-Derived Islet Lineage Intermediates. Current Protocols in Stem Cell Biology. 53: e111. PMID 32521122 DOI: 10.1002/cpsc.111 |
0.49 |
|
| 2020 |
Davis JC, Alves TC, Helman A, Chen JC, Kenty JH, Cardone RL, Liu DR, Kibbey RG, Melton DA. Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis. Cell Reports. 31: 107623. PMID 32402282 DOI: 10.1016/J.Celrep.2020.107623 |
0.415 |
|
| 2020 |
Peterson QP, Veres A, Chen L, Slama MQ, Kenty JHR, Hassoun S, Brown MR, Dou H, Duffy CD, Zhou Q, Matveyenko AV, Tyrberg B, Sörhede-Winzell M, Rorsman P, Melton DA. A method for the generation of human stem cell-derived alpha cells. Nature Communications. 11: 2241. PMID 32382023 DOI: 10.1038/S41467-020-16049-3 |
0.782 |
|
| 2020 |
Helman A, Cangelosi AL, Davis JC, Pham Q, Rothman A, Faust AL, Straubhaar JR, Sabatini DM, Melton DA. A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion. Cell Metabolism. PMID 32375022 DOI: 10.1016/j.cmet.2020.04.004 |
0.379 |
|
| 2020 |
Helman A, Melton DA. A Stem Cell Approach to Cure Type 1 Diabetes. Cold Spring Harbor Perspectives in Biology. PMID 32122884 DOI: 10.1101/cshperspect.a035741 |
0.426 |
|
| 2020 |
Rosado-Olivieri EA, Aigha II, Kenty JH, Melton DA. Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human β Cells. Cell Metabolism. PMID 31928884 DOI: 10.1016/j.cmet.2019.12.009 |
0.444 |
|
| 2019 |
Alvarez-Dominguez JR, Donaghey J, Rasouli N, Kenty JHR, Helman A, Charlton J, Straubhaar JR, Meissner A, Melton DA. Circadian Entrainment Triggers Maturation of Human In Vitro Islets. Cell Stem Cell. PMID 31839570 DOI: 10.1016/J.Stem.2019.11.011 |
0.437 |
|
| 2019 |
Davis JC, Helman A, Rivera-Feliciano J, Langston CM, Engquist EN, Melton DA. Live Cell Monitoring and Enrichment of Stem Cell-Derived β Cells Using Intracellular Zinc Content as a Population Marker. Current Protocols in Stem Cell Biology. 51: e99. PMID 31756031 DOI: 10.1002/cpsc.99 |
0.83 |
|
| 2019 |
Garbern JC, Helman A, Sereda R, Sarikhani M, Ahmed A, Escalante GO, Ogurlu R, Kim SL, Zimmerman JF, Cho A, MacQueen L, Bezzerides VJ, Parker KK, Melton DA, Lee RT. Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells via p53-Induced Quiescence. Circulation. PMID 31707831 DOI: 10.1161/Circulationaha.119.044205 |
0.403 |
|
| 2019 |
Kotliar D, Veres A, Nagy MA, Tabrizi S, Hodis E, Melton DA, Sabeti PC. Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq. Elife. 8. PMID 31282856 DOI: 10.7554/eLife.43803 |
0.403 |
|
| 2019 |
Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA. Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. Cell Reports. 27: 2281-2291.e5. PMID 31116975 DOI: 10.1016/J.Celrep.2019.04.083 |
0.517 |
|
| 2019 |
Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA. Charting cellular identity during human in vitro β-cell differentiation. Nature. PMID 31068696 DOI: 10.1038/s41586-019-1168-5 |
0.817 |
|
| 2019 |
Han X, Wang M, Duan S, Franco PJ, Kenty JH, Hedrick P, Xia Y, Allen A, Ferreira LMR, Strominger JL, Melton DA, Meissner TB, Cowan CA. Generation of hypoimmunogenic human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31040209 DOI: 10.1073/Pnas.1902566116 |
0.642 |
|
| 2019 |
Rosado-Olivieri EA, Anderson K, Kenty JH, Melton DA. YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells. Nature Communications. 10: 1464. PMID 30931946 DOI: 10.1038/s41467-019-09404-6 |
0.504 |
|
| 2019 |
Chien KR, Frisén J, Fritsche-Danielson R, Melton DA, Murry CE, Weissman IL. Regenerating the field of cardiovascular cell therapy. Nature Biotechnology. PMID 30778231 DOI: 10.1038/S41587-019-0042-1 |
0.302 |
|
| 2019 |
Alagpulinsa DA, Cao JJL, Driscoll RK, Sîrbulescu RF, Penson MFE, Sremac M, Engquist EN, Brauns TA, Markmann JF, Melton DA, Poznansky MC. Alginate-microencapsulation of human stem cell-derived β cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30748094 DOI: 10.1111/Ajt.15308 |
0.441 |
|
| 2019 |
Tsai SL, Baselga-Garriga C, Melton DA. Blastemal progenitors modulate immune signaling during early limb regeneration. Development (Cambridge, England). 146. PMID 30602532 DOI: 10.1242/dev.169128 |
0.42 |
|
| 2019 |
Kotliar D, Veres A, Nagy MA, Tabrizi S, Hodis E, Melton DA, Sabeti PC. Author response: Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq Elife. DOI: 10.7554/Elife.43803.044 |
0.4 |
|
| 2019 |
HELMAN A, MELTON D. 331-LB: A Switch in Nutrient Sensing Controls Functional Maturation of Pancreatic Beta Cells Diabetes. 68: 331-LB. DOI: 10.2337/DB19-331-LB |
0.402 |
|
| 2018 |
Mahmoud AI, Galdos FX, Dinan KA, Jedrychowski MP, Davis JC, Vujic A, Rachmin I, Shigley C, Pancoast JR, Lee S, Hollister-Lock J, MacGillivray CM, Gygi SP, Melton DA, Weir GC, et al. Apolipoprotein E is a pancreatic extracellular factor that maintains mature β-cell gene expression. Plos One. 13: e0204595. PMID 30303984 DOI: 10.1371/Journal.Pone.0204595 |
0.461 |
|
| 2018 |
Zhou Q, Melton DA. Author Correction: Pancreas regeneration. Nature. PMID 29925956 DOI: 10.1038/s41586-018-0294-9 |
0.606 |
|
| 2018 |
Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, et al. Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells. Transplantation. PMID 29781950 DOI: 10.1097/Tp.0000000000002217 |
0.79 |
|
| 2018 |
Zhou Q, Melton DA. Pancreas regeneration. Nature. 557: 351-358. PMID 29769672 DOI: 10.1038/s41586-018-0088-0 |
0.576 |
|
| 2018 |
Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R. Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas. Proceedings of the National Academy of Sciences of the United States of America. PMID 29599125 DOI: 10.1073/Pnas.1702059115 |
0.462 |
|
| 2016 |
Yi P, Park JS, Melton DA. Retraction Notice to: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation. Cell. PMID 28038792 DOI: 10.1016/j.cell.2016.12.017 |
0.588 |
|
| 2016 |
Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I. A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure. Cell Systems. PMID 27667365 DOI: 10.1016/J.Cels.2016.08.011 |
0.506 |
|
| 2016 |
Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA. Corrigendum: Generation of stem cell-derived β-cells from patients with type 1 diabetes. Nature Communications. 7: 12379. PMID 27487970 DOI: 10.1038/ncomms12379 |
0.396 |
|
| 2016 |
Cox AR, Barrandon O, Cai EP, Rios JS, Chavez J, Bonnyman CW, Lam CJ, Yi P, Melton DA, Kushner JA. Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy. Plos One. 11: e0159276. PMID 27410263 DOI: 10.1371/journal.pone.0159276 |
0.584 |
|
| 2016 |
Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA. Generation of stem cell-derived β-cells from patients with type 1 diabetes. Nature Communications. 7: 11463. PMID 27163171 DOI: 10.1038/ncomms11463 |
0.407 |
|
| 2016 |
Vegas AJ, Veiseh O, G M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, ... ... Melton DA, et al. Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nature Medicine. 22: 446. PMID 27050590 DOI: 10.1038/Nm0416-446E |
0.404 |
|
| 2016 |
Melton DA. Applied Developmental Biology: Making Human Pancreatic Beta Cells for Diabetics. Current Topics in Developmental Biology. 117: 65-73. PMID 26969972 DOI: 10.1016/bs.ctdb.2015.11.013 |
0.456 |
|
| 2016 |
Ariyachet C, Tovaglieri A, Xiang G, Lu J, Shah MS, Richmond CA, Verbeke C, Melton DA, Stanger BZ, Mooney D, Shivdasani RA, Mahony S, Xia Q, Breault DT, Zhou Q. Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation. Cell Stem Cell. PMID 26908146 DOI: 10.1016/J.Stem.2016.01.003 |
0.651 |
|
| 2016 |
Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, ... ... Melton DA, et al. Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice. Nature Medicine. PMID 26808346 DOI: 10.1038/Nm.4030 |
0.423 |
|
| 2015 |
Ben-Zvi D, Barrandon O, Hadley S, Blum B, Peterson QP, Melton DA. Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621734 DOI: 10.1073/Pnas.1513872112 |
0.788 |
|
| 2015 |
Chetty S, Engquist EN, Mehanna E, Lui KO, Tsankov AM, Melton DA. A Src inhibitor regulates the cell cycle of human pluripotent stem cells and improves directed differentiation. The Journal of Cell Biology. 210: 1257-68. PMID 26416968 DOI: 10.1083/Jcb.201502035 |
0.458 |
|
| 2015 |
Kenty JH, Melton DA. Testing pancreatic islet function at the single cell level by calcium influx with associated marker expression. Plos One. 10: e0122044. PMID 25853429 DOI: 10.1371/journal.pone.0122044 |
0.439 |
|
| 2015 |
Ben-Zvi D, Melton DA. Modeling human nutrition using human embryonic stem cells. Cell. 161: 12-7. PMID 25815980 DOI: 10.1016/J.Cell.2015.02.039 |
0.677 |
|
| 2015 |
Chetty S, Engquist E, Mehanna E, Lui K, Tsankov A, Melton D. A Src inhibitor regulates the cell cycle of human pluripotent stem cells and improves directed differentiation The Journal of Experimental Medicine. 212: 21211OIA91. DOI: 10.1084/jem.21211OIA91 |
0.369 |
|
| 2014 |
Yi P, Park JS, Melton DA. Perspectives on the activities of ANGPTL8/betatrophin. Cell. 159: 467-8. PMID 25417096 DOI: 10.1016/j.cell.2014.09.028 |
0.557 |
|
| 2014 |
Pagliuca FW, Millman JR, Gürtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA. Generation of functional human pancreatic β cells in vitro. Cell. 159: 428-39. PMID 25303535 DOI: 10.1016/J.Cell.2014.09.040 |
0.799 |
|
| 2014 |
Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA. Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway. Elife. 3: e02809. PMID 25233132 DOI: 10.7554/Elife.02809 |
0.806 |
|
| 2014 |
Li W, Nakanishi M, Zumsteg A, Shear M, Wright C, Melton DA, Zhou Q. In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes. Elife. 3: e01846. PMID 24714494 DOI: 10.7554/eLife.01846.027 |
0.652 |
|
| 2014 |
Hrvatin S, Deng F, O'Donnell CW, Gifford DK, Melton DA. MARIS: method for analyzing RNA following intracellular sorting. Plos One. 9: e89459. PMID 24594682 DOI: 10.1371/Journal.Pone.0089459 |
0.746 |
|
| 2014 |
Hrvatin S, O'Donnell CW, Deng F, Millman JR, Pagliuca FW, DiIorio P, Rezania A, Gifford DK, Melton DA. Differentiated human stem cells resemble fetal, not adult, β cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 3038-43. PMID 24516164 DOI: 10.1073/Pnas.1400709111 |
0.795 |
|
| 2014 |
Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA. Author response: Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway Elife. DOI: 10.7554/Elife.02809.018 |
0.786 |
|
| 2014 |
Li W, Nakanishi M, Zumsteg A, Shear M, Wright C, Melton DA, Zhou Q. Re: In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes Elife. 2014. DOI: 10.7554/eLife.01846.028 |
0.611 |
|
| 2013 |
Tajonar A, Maehr R, Hu G, Sneddon JB, Rivera-Feliciano J, Cohen DE, Elledge SJ, Melton DA. Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells. Stem Cells (Dayton, Ohio). 31: 2833-41. PMID 23765749 DOI: 10.1002/Stem.1445 |
0.795 |
|
| 2013 |
Pagliuca FW, Melton DA. How to make a functional β-cell. Development (Cambridge, England). 140: 2472-83. PMID 23715541 DOI: 10.1242/dev.093187 |
0.515 |
|
| 2013 |
Yi P, Park JS, Melton DA. Betatrophin: a hormone that controls pancreatic β cell proliferation. Cell. 153: 747-58. PMID 23623304 DOI: 10.1016/j.cell.2013.04.008 |
0.603 |
|
| 2013 |
Chetty S, Pagliuca FW, Honore C, Kweudjeu A, Rezania A, Melton DA. A simple tool to improve pluripotent stem cell differentiation. Nature Methods. 10: 553-6. PMID 23584186 DOI: 10.1038/Nmeth.2442 |
0.486 |
|
| 2013 |
Chen AE, Borowiak M, Sherwood RI, Kweudjeu A, Melton DA. Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation. Development (Cambridge, England). 140: 675-86. PMID 23293299 DOI: 10.1242/Dev.085431 |
0.78 |
|
| 2013 |
Carolan PJ, Melton DA. New findings in pancreatic and intestinal endocrine development to advance regenerative medicine. Current Opinion in Endocrinology, Diabetes, and Obesity. 20: 1-7. PMID 23249759 DOI: 10.1097/MED.0b013e32835bc380 |
0.503 |
|
| 2013 |
Chetty S, Pagliuca FW, Honore C, Melton DA. A protocol to improve pluripotent stem cell differentiation Protocol Exchange. DOI: 10.1038/Protex.2013.050 |
0.433 |
|
| 2013 |
Yamanaka S, Wagers A, Muotri A, Srivastava D, Melton D, Blanpain C, Gurdon J, Fuchs E, Jaenisch R. XStem cells in translation Cell. 153: X1177-1179. DOI: 10.1016/J.Cell.2013.05.036 |
0.564 |
|
| 2013 |
Dor Y, Melton DA. Pancreatic Stem Cells Handbook of Stem Cells. 2: 819-826. DOI: 10.1016/B978-0-12-385942-6.00068-8 |
0.627 |
|
| 2012 |
Sneddon JB, Borowiak M, Melton DA. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature. 491: 765-8. PMID 23041930 DOI: 10.1038/Nature11463 |
0.515 |
|
| 2012 |
Blum B, Hrvatin SS, Schuetz C, Bonal C, Rezania A, Melton DA. Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3. Nature Biotechnology. 30: 261-4. PMID 22371083 DOI: 10.1038/Nbt.2141 |
0.813 |
|
| 2012 |
Annes JP, Ryu JH, Lam K, Carolan PJ, Utz K, Hollister-Lock J, Arvanites AC, Rubin LL, Weir G, Melton DA. Adenosine kinase inhibition selectively promotes rodent and porcine islet β-cell replication. Proceedings of the National Academy of Sciences of the United States of America. 109: 3915-20. PMID 22345561 DOI: 10.1073/pnas.1201149109 |
0.43 |
|
| 2011 |
Egli D, Chen AE, Saphier G, Powers D, Alper M, Katz K, Berger B, Goland R, Leibel RL, Melton DA, Eggan K. Impracticality of egg donor recruitment in the absence of compensation. Cell Stem Cell. 9: 293-4. PMID 21982228 DOI: 10.1016/J.Stem.2011.08.002 |
0.637 |
|
| 2011 |
Egli D, Chen AE, Saphier G, Ichida J, Fitzgerald C, Go KJ, Acevedo N, Patel J, Baetscher M, Kearns WG, Goland R, Leibel RL, Melton DA, Eggan K. Reprogramming within hours following nuclear transfer into mouse but not human zygotes. Nature Communications. 2: 488. PMID 21971503 DOI: 10.1038/Ncomms1503 |
0.624 |
|
| 2011 |
Sherwood RI, Maehr R, Mazzoni EO, Melton DA. Wnt signaling specifies and patterns intestinal endoderm. Mechanisms of Development. 128: 387-400. PMID 21854845 DOI: 10.1016/J.Mod.2011.07.005 |
0.811 |
|
| 2011 |
Melton DA. Using stem cells to study and possibly treat type 1 diabetes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 2307-11. PMID 21727136 DOI: 10.1098/rstb.2011.0019 |
0.431 |
|
| 2011 |
Cohen DE, Melton D. Turning straw into gold: directing cell fate for regenerative medicine. Nature Reviews. Genetics. 12: 243-52. PMID 21386864 DOI: 10.1038/nrg2938 |
0.494 |
|
| 2010 |
Niakan KK, Ji H, Maehr R, Vokes SA, Rodolfa KT, Sherwood RI, Yamaki M, Dimos JT, Chen AE, Melton DA, McMahon AP, Eggan K. Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. Genes & Development. 24: 312-26. PMID 20123909 DOI: 10.1101/Gad.1833510 |
0.824 |
|
| 2010 |
Chen S, Rajagopal J, Zhou Q, Melton DA, Koh A, Senior P, Shapiro AMJ, Barbu AR, Welsh N. Other Future Directions Textbook of Diabetes: Fourth Edition. 1045-1069. DOI: 10.1002/9781444324808.ch61 |
0.57 |
|
| 2009 |
Borowiak M, Melton DA. How to make beta cells? Current Opinion in Cell Biology. 21: 727-32. PMID 19781928 DOI: 10.1016/j.ceb.2009.08.006 |
0.448 |
|
| 2009 |
Maehr R, Chen S, Snitow M, Ludwig T, Yagasaki L, Goland R, Leibel RL, Melton DA. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 106: 15768-73. PMID 19720998 DOI: 10.1073/Pnas.0906894106 |
0.755 |
|
| 2009 |
Brennand K, Melton D. Slow and steady is the key to β-cell replication Journal of Cellular and Molecular Medicine. 13: 472-487. PMID 19379145 DOI: 10.1111/J.1582-4934.2008.00635.X |
0.624 |
|
| 2009 |
Guseh JS, Bores SA, Stanger BZ, Zhou Q, Anderson WJ, Melton DA, Rajagopal J. Notch signaling promotes airway mucous metaplasia and inhibits alveolar development. Development (Cambridge, England). 136: 1751-9. PMID 19369400 DOI: 10.1242/Dev.029249 |
0.809 |
|
| 2009 |
Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell. 4: 348-58. PMID 19341624 DOI: 10.1016/J.Stem.2009.01.014 |
0.758 |
|
| 2009 |
Chen S, Borowiak M, Fox JL, Maehr R, Osafune K, Davidow L, Lam K, Peng LF, Schreiber SL, Rubin LL, Melton D. A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nature Chemical Biology. 5: 258-65. PMID 19287398 DOI: 10.1038/Nchembio.154 |
0.776 |
|
| 2009 |
Chen AE, Egli D, Niakan K, Deng J, Akutsu H, Yamaki M, Cowan C, Fitz-Gerald C, Zhang K, Melton DA, Eggan K. Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. Cell Stem Cell. 4: 103-6. PMID 19200798 DOI: 10.1016/J.Stem.2008.12.001 |
0.759 |
|
| 2009 |
Sherwood RI, Chen TY, Melton DA. Transcriptional dynamics of endodermal organ formation. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 29-42. PMID 19097184 DOI: 10.1002/Dvdy.21810 |
0.708 |
|
| 2009 |
Lanza R, Gearhart J, Hogan B, Melton D, Pedersen R, Thomas ED, Thomson J, Wilmut SI. Essentials of Stem Cell Biology Essentials of Stem Cell Biology. |
0.353 |
|
| 2008 |
Zhou Q, Melton DA. Pathways to new beta cells. Cold Spring Harbor Symposia On Quantitative Biology. 73: 175-81. PMID 19478324 DOI: 10.1101/sqb.2008.73.002 |
0.595 |
|
| 2008 |
Gurdon JB, Melton DA. Nuclear reprogramming in cells. Science (New York, N.Y.). 322: 1811-5. PMID 19095934 DOI: 10.1126/Science.1160810 |
0.636 |
|
| 2008 |
Zhou Q, Melton DA. Extreme makeover: converting one cell into another. Cell Stem Cell. 3: 382-8. PMID 18940730 DOI: 10.1016/j.stem.2008.09.015 |
0.64 |
|
| 2008 |
Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W, Melton DA. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nature Biotechnology. 26: 1269-75. PMID 18849973 DOI: 10.1038/Nbt.1502 |
0.823 |
|
| 2008 |
Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature. 455: 627-32. PMID 18754011 DOI: 10.1038/Nature07314 |
0.835 |
|
| 2008 |
Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nature Biotechnology. 26: 795-7. PMID 18568017 DOI: 10.1038/Nbt1418 |
0.8 |
|
| 2008 |
Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA. Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme. Development (Cambridge, England). 135: 1625-34. PMID 18367557 DOI: 10.1242/Dev.015495 |
0.795 |
|
| 2008 |
Osafune K, Caron L, Borowiak M, Martinez RJ, Fitz-Gerald CS, Sato Y, Cowan CA, Chien KR, Melton DA. Marked differences in differentiation propensity among human embryonic stem cell lines. Nature Biotechnology. 26: 313-5. PMID 18278034 DOI: 10.1038/Nbt1383 |
0.68 |
|
| 2008 |
Dor Y, Melton DA. Facultative endocrine progenitor cells in the adult pancreas. Cell. 132: 183-4. PMID 18243094 DOI: 10.1016/J.Cell.2008.01.004 |
0.661 |
|
| 2008 |
Anderson WJ, Zhou Q, Alcalde V, Kaneko OF, Blank LJ, Sherwood RI, Guseh JS, Rajagopal J, Melton DA. Genetic targeting of the endoderm with claudin-6CreER. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 504-12. PMID 18213590 DOI: 10.1002/Dvdy.21437 |
0.822 |
|
| 2007 |
Chen AE, Melton DA. Derivation of human embryonic stem cells by immunosurgery. Journal of Visualized Experiments : Jove. 574. PMID 18989406 DOI: 10.3791/574 |
0.479 |
|
| 2007 |
Zhou Q, Chipperfield H, Melton DA, Wong WH. A gene regulatory network in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 16438-43. PMID 17940043 DOI: 10.1073/pnas.0701014104 |
0.369 |
|
| 2007 |
Nir T, Melton DA, Dor Y. Recovery from diabetes in mice by beta cell regeneration. The Journal of Clinical Investigation. 117: 2553-61. PMID 17786244 DOI: 10.1172/Jci32959 |
0.637 |
|
| 2007 |
Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA. A multipotent progenitor domain guides pancreatic organogenesis. Developmental Cell. 13: 103-14. PMID 17609113 DOI: 10.1016/J.Devcel.2007.06.001 |
0.822 |
|
| 2007 |
Brennand K, Huangfu D, Melton D. All beta cells contribute equally to islet growth and maintenance. Plos Biology. 5: e163. PMID 17535113 DOI: 10.1371/Journal.Pbio.0050163 |
0.784 |
|
| 2007 |
Sherwood RI, Jitianu C, Cleaver O, Shaywitz DA, Lamenzo JO, Chen AE, Golub TR, Melton DA. Prospective isolation and global gene expression analysis of definitive and visceral endoderm. Developmental Biology. 304: 541-55. PMID 17328885 DOI: 10.1016/J.Ydbio.2007.01.011 |
0.728 |
|
| 2007 |
Stanger BZ, Tanaka AJ, Melton DA. Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver. Nature. 445: 886-91. PMID 17259975 DOI: 10.1038/Nature05537 |
0.371 |
|
| 2007 |
Greenwood AL, Li S, Jones K, Melton DA. Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate. Mechanisms of Development. 124: 97-107. PMID 17196797 DOI: 10.1016/j.mod.2006.11.002 |
0.722 |
|
| 2007 |
Brennand K, Huangfu D, Melton D. Correction: All ß Cells Contribute Equally to Islet Growth and Maintenance Plos Biology. 5: e240. DOI: 10.1371/Journal.Pbio.0050240 |
0.741 |
|
| 2007 |
Osafune K, Chen AE, Melton DA. Part A: Directed Differentiation of Human Embryonic Stem Cells into Early Endoderm Cells Human Embryonic Stem Cells: the Practical Handbook. 179-186. DOI: 10.1002/9780470511619.ch12a |
0.401 |
|
| 2006 |
Akutsu H, Cowan CA, Melton D. Human Embryonic Stem Cells Methods in Enzymology. 418: 78-92. PMID 17141030 DOI: 10.1016/S0076-6879(06)18005-2 |
0.694 |
|
| 2006 |
Melton DA. Reversal of type 1 diabetes in mice. The New England Journal of Medicine. 355: 89-90. PMID 16823003 DOI: 10.1056/NEJMcibr062559 |
0.346 |
|
| 2006 |
Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, ... ... Melton DA, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 125: 301-13. PMID 16630818 DOI: 10.1016/J.Cell.2006.02.043 |
0.485 |
|
| 2006 |
Nikolova G, Jabs N, Konstantinova I, Domogatskaya A, Tryggvason K, Sorokin L, Fässler R, Gu G, Gerber HP, Ferrara N, Melton DA, Lammert E. The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. Developmental Cell. 10: 397-405. PMID 16516842 DOI: 10.1016/j.devcel.2006.01.015 |
0.404 |
|
| 2006 |
Yang X, Eggan K, Seidel G, Jaenisch R, Melton D. A simple system of checks and balances to cut fraud. Nature. 439: 782. PMID 16482128 DOI: 10.1038/439782B |
0.498 |
|
| 2005 |
Murtaugh LC, Law AC, Dor Y, Melton DA. Beta-catenin is essential for pancreatic acinar but not islet development. Development (Cambridge, England). 132: 4663-74. PMID 16192304 DOI: 10.1242/Dev.02063 |
0.651 |
|
| 2005 |
Stanger BZ, Stiles B, Lauwers GY, Bardeesy N, Mendoza M, Wang Y, Greenwood A, Cheng KH, McLaughlin M, Brown D, Depinho RA, Wu H, Melton DA, Dor Y. Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell. 8: 185-95. PMID 16169464 DOI: 10.1016/J.Ccr.2005.07.015 |
0.762 |
|
| 2005 |
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 122: 947-56. PMID 16153702 DOI: 10.1016/J.Cell.2005.08.020 |
0.466 |
|
| 2005 |
Cowan CA, Atienza J, Melton DA, Eggan K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science (New York, N.Y.). 309: 1369-73. PMID 16123299 DOI: 10.1126/Science.1116447 |
0.792 |
|
| 2005 |
Stanger BZ, Datar R, Murtaugh LC, Melton DA. Direct regulation of intestinal fate by Notch. Proceedings of the National Academy of Sciences of the United States of America. 102: 12443-8. PMID 16107537 DOI: 10.1073/Pnas.0505690102 |
0.417 |
|
| 2004 |
Melton DA, Daley GQ, Jennings CG. Altered nuclear transfer in stem-cell research - a flawed proposal. The New England Journal of Medicine. 351: 2791-2. PMID 15625329 DOI: 10.1056/Nejmp048348 |
0.4 |
|
| 2004 |
Hansson M, Tonning A, Frandsen U, Petri A, Rajagopal J, Englund MCO, Heller RS, Håkansson J, Fleckner J, Sköld HN, Melton D, Semb H, Serup P. Artifactual insulin release from differentiated embryonic stem cells Diabetes. 53: 2603-2609. PMID 15448090 DOI: 10.2337/Diabetes.53.10.2603 |
0.7 |
|
| 2004 |
Dor Y, Melton DA. How important are adult stem cells for tissue maintenance? Cell Cycle (Georgetown, Tex.). 3: 1104-6. PMID 15326371 DOI: 10.4161/Cc.3.9.1096 |
0.674 |
|
| 2004 |
Annerén C, Cowan CA, Melton DA. The Src family of tyrosine kinases is important for embryonic stem cell self-renewal. The Journal of Biological Chemistry. 279: 31590-8. PMID 15148312 DOI: 10.1074/jbc.M403547200 |
0.644 |
|
| 2004 |
Dor Y, Brown J, Martinez OI, Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature. 429: 41-6. PMID 15129273 DOI: 10.1038/Nature02520 |
0.778 |
|
| 2004 |
Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA. Derivation of embryonic stem-cell lines from human blastocysts. The New England Journal of Medicine. 350: 1353-6. PMID 14999088 DOI: 10.1056/Nejmsr040330 |
0.683 |
|
| 2004 |
Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B, Melton DA. Global expression analysis of gene regulatory pathways during endocrine pancreatic development. Development (Cambridge, England). 131: 165-79. PMID 14660441 DOI: 10.1242/dev.00921 |
0.479 |
|
| 2003 |
Murtaugh LC, Stanger BZ, Kwan KM, Melton DA. Notch signaling controls multiple steps of pancreatic differentiation. Proceedings of the National Academy of Sciences of the United States of America. 100: 14920-5. PMID 14657333 DOI: 10.1073/Pnas.2436557100 |
0.481 |
|
| 2003 |
Murtaugh LC, Melton DA. Genes, signals, and lineages in pancreas development. Annual Review of Cell and Developmental Biology. 19: 71-89. PMID 14570564 DOI: 10.1146/annurev.cellbio.19.111301.144752 |
0.47 |
|
| 2003 |
Kumar M, Melton D. Pancreas specification: A budding question Current Opinion in Genetics and Development. 13: 401-407. PMID 12888014 DOI: 10.1016/S0959-437X(03)00089-3 |
0.733 |
|
| 2003 |
Kumar M, Jordan N, Melton D, Grapin-Botton A. Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate Developmental Biology. 259: 109-122. PMID 12812792 DOI: 10.1016/S0012-1606(03)00183-0 |
0.762 |
|
| 2003 |
Cleaver O, Melton DA. Endothelial signaling during development. Nature Medicine. 9: 661-8. PMID 12778164 DOI: 10.1038/nm0603-661 |
0.379 |
|
| 2003 |
Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.). 300: 913-6. PMID 12738841 DOI: 10.1126/Science.1082940 |
0.724 |
|
| 2003 |
Chiang MK, Melton DA. Single-cell transcript analysis of pancreas development. Developmental Cell. 4: 383-93. PMID 12636919 DOI: 10.1016/S1534-5807(03)00035-2 |
0.497 |
|
| 2003 |
Rajagopal J, Anderson WJ, Kume S, Martinez OI, Melton DA. Insulin staining of ES cell progeny from insulin uptake. Science (New York, N.Y.). 299: 363. PMID 12532008 DOI: 10.1126/science.1077838 |
0.718 |
|
| 2003 |
Lammert E, Cleaver O, Melton D. Role of endothelial cells in early pancreas and liver development Mechanisms of Development. 120: 59-64. PMID 12490296 DOI: 10.1016/S0925-4773(02)00332-5 |
0.391 |
|
| 2003 |
Gu G, Brown JR, Melton DA. Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis. Mechanisms of Development. 120: 35-43. PMID 12490294 DOI: 10.1016/S0925-4773(02)00330-1 |
0.719 |
|
| 2002 |
Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science (New York, N.Y.). 298: 597-600. PMID 12228720 DOI: 10.1126/Science.1072530 |
0.494 |
|
| 2002 |
Scearce LM, Brestelli JE, McWeeney SK, Lee CS, Mazzarelli J, Pinney DF, Pizarro A, Stoeckert CJ, Clifton SW, Permutt MA, Brown J, Melton DA, Kaestner KH. Functional genomics of the endocrine pancreas: the pancreas clone set and PancChip, new resources for diabetes research. Diabetes. 51: 1997-2004. PMID 12086925 DOI: 10.2337/Diabetes.51.7.1997 |
0.579 |
|
| 2002 |
Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development (Cambridge, England). 129: 2447-57. PMID 11973276 |
0.411 |
|
| 2002 |
Fishman MP, Melton DA. Pancreatic lineage analysis using a retroviral vector in embryonic mice demonstrates a common progenitor for endocrine and exocrine cells. The International Journal of Developmental Biology. 46: 201-7. PMID 11934148 DOI: 10.1387/ijdb.011552 |
0.5 |
|
| 2001 |
Lammert E, Cleaver O, Melton D. Induction of Pancreatic Differentiation by Signals from Blood Vessels Science. 294: 564-567. PMID 11577200 DOI: 10.1126/Science.1064344 |
0.338 |
|
| 2001 |
Grapin-Botton A, Majithia AR, Melton DA. Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes. Genes & Development. 15: 444-54. PMID 11230152 DOI: 10.1101/gad.846001 |
0.487 |
|
| 2000 |
Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA. Regulation of pancreas development by hedgehog signaling. Development (Cambridge, England). 127: 4905-13. PMID 11044404 |
0.614 |
|
| 2000 |
Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA, Benvenisty N. Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 11307-12. PMID 11027332 DOI: 10.1073/Pnas.97.21.11307 |
0.655 |
|
| 2000 |
Kim SK, Hebrok M, Li E, Oh SP, Schrewe H, Harmon EB, Lee JS, Melton DA. Activin receptor patterning of foregut organogenesis. Genes & Development. 14: 1866-71. PMID 10921901 DOI: 10.1101/Gad.14.15.1866 |
0.617 |
|
| 2000 |
Kelly OG, Melton DA. Development of the pancreas in Xenopus laevis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 218: 615-27. PMID 10906780 DOI: 10.1002/1097-0177(2000)9999:9999<::AID-DVDY1027>3.0.CO;2-8 |
0.375 |
|
| 2000 |
Lammert E, Brown J, Melton DA. Notch gene expression during pancreatic organogenesis. Mechanisms of Development. 94: 199-203. PMID 10842072 DOI: 10.1016/S0925-4773(00)00317-8 |
0.68 |
|
| 2000 |
Ramalho-Santos M, Melton DA, McMahon AP. Hedgehog signals regulate multiple aspects of gastrointestinal development. Development (Cambridge, England). 127: 2763-72. PMID 10821773 |
0.304 |
|
| 1999 |
Wells JM, Melton DA. Vertebrate endoderm development. Annual Review of Cell and Developmental Biology. 15: 393-410. PMID 10611967 DOI: 10.1146/annurev.cellbio.15.1.393 |
0.376 |
|
| 1999 |
Hebrok M, Kim SK, Melton DA. Screening for novel pancreatic genes expressed during embryogenesis. Diabetes. 48: 1550-6. PMID 10426372 DOI: 10.2337/Diabetes.48.8.1550 |
0.603 |
|
| 1998 |
Kim SK, Melton DA. Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 95: 13036-41. PMID 9789036 DOI: 10.1073/pnas.95.22.13036 |
0.408 |
|
| 1998 |
Henry GL, Melton DA. Mixer, a homeobox gene required for endoderm development. Science (New York, N.Y.). 281: 91-6. PMID 9651252 DOI: 10.1126/science.281.5373.91 |
0.437 |
|
| 1998 |
Hebrok M, Kim SK, Melton DA. Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes & Development. 12: 1705-13. PMID 9620856 DOI: 10.1101/Gad.12.11.1705 |
0.636 |
|
| 1997 |
Kim SK, Hebrok M, Melton DA. Pancreas development in the chick embryo. Cold Spring Harbor Symposia On Quantitative Biology. 62: 377-83. PMID 9598372 DOI: 10.1101/Sqb.1997.062.01.045 |
0.584 |
|
| 1997 |
Kim SK, Hebrok M, Melton DA. Notochord to endoderm signaling is required for pancreas development. Development (Cambridge, England). 124: 4243-52. PMID 9334273 |
0.606 |
|
| 1997 |
Joseph EM, Melton DA. Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer. Developmental Biology. 184: 367-72. PMID 9133442 DOI: 10.1006/dbio.1997.8510 |
0.353 |
|
| 1997 |
Hemmati-Brivanlou A, Melton D. Vertebrate embryonic cells will become nerve cells unless told otherwise. Cell. 88: 13-7. PMID 9019398 DOI: 10.1016/S0092-8674(00)81853-X |
0.406 |
|
| 1996 |
Derynck R, Gelbart WM, Harland RM, Heldin CH, Kern SE, Massagué J, Melton DA, Mlodzik M, Padgett RW, Roberts AB, Smith J, Thomsen GH, Vogelstein B, Wang XF. Nomenclature: vertebrate mediators of TGFbeta family signals. Cell. 87: 173. PMID 8861901 DOI: 10.1016/S0092-8674(00)81335-5 |
0.69 |
|
| 1996 |
Reilly KM, Melton DA. Short-range signaling by candidate morphogens of the TGF beta family and evidence for a relay mechanism of induction. Cell. 86: 743-54. PMID 8797821 DOI: 10.1016/S0092-8674(00)80149-X |
0.438 |
|
| 1996 |
Klein PS, Melton DA. A molecular mechanism for the effect of lithium on development. Proceedings of the National Academy of Sciences of the United States of America. 93: 8455-9. PMID 8710892 DOI: 10.1073/pnas.93.16.8455 |
0.321 |
|
| 1996 |
Graff JM, Bansal A, Melton DA. Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily. Cell. 85: 479-87. PMID 8653784 DOI: 10.1016/S0092-8674(00)81249-0 |
0.342 |
|
| 1996 |
Dohrmann CE, Kessler DS, Melton DA. Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1. Developmental Biology. 175: 108-17. PMID 8608857 DOI: 10.1006/dbio.1996.0099 |
0.304 |
|
| 1995 |
Klein PS, Melton DA. Translational control of activin in Xenopus laevis embryos. Developmental Genetics. 17: 55-64. PMID 7554495 DOI: 10.1002/dvg.1020170107 |
0.351 |
|
| 1995 |
Kelly OG, Melton DA. Induction and patterning of the vertebrate nervous system. Trends in Genetics : Tig. 11: 273-8. PMID 7482777 DOI: 10.1016/S0168-9525(00)89074-5 |
0.319 |
|
| 1994 |
Hemmati-Brivanlou A, Kelly OG, Melton DA. Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell. 77: 283-95. PMID 8168135 DOI: 10.1016/0092-8674(94)90320-4 |
0.322 |
|
| 1994 |
Hemmati-Brivanlou A, Melton DA. Inhibition of activin receptor signaling promotes neuralization in Xenopus. Cell. 77: 273-81. PMID 8168134 DOI: 10.1016/0092-8674(94)90319-0 |
0.382 |
|
| 1994 |
Klein PS, Melton DA. Hormonal regulation of embryogenesis: the formation of mesoderm in Xenopus laevis. Endocrine Reviews. 15: 326-41. PMID 8076585 DOI: 10.1210/edrv-15-3-326 |
0.398 |
|
| 1994 |
Klein PS, Melton DA. Induction of mesoderm in Xenopus laevis embryos by translation initiation factor 4E. Science (New York, N.Y.). 265: 803-6. PMID 8047887 DOI: 10.1126/Science.8047887 |
0.334 |
|
| 1994 |
Wilson PA, Melton DA. Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication. Current Biology : Cb. 4: 676-86. PMID 7953553 DOI: 10.1016/S0960-9822(00)00152-4 |
0.427 |
|
| 1994 |
Kessler DS, Melton DA. Vertebrate embryonic induction: mesodermal and neural patterning. Science (New York, N.Y.). 266: 596-604. PMID 7939714 DOI: 10.1126/Science.7939714 |
0.364 |
|
| 1993 |
Dohrmann CE, Hemmati-Brivanlou A, Thomsen GH, Fields A, Woolf TM, Melton DA. Expression of activin mRNA during early development in Xenopus laevis. Developmental Biology. 157: 474-83. PMID 8500654 DOI: 10.1006/Dbio.1993.1150 |
0.701 |
|
| 1993 |
Thomsen GH, Melton DA. Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell. 74: 433-41. PMID 8348610 DOI: 10.1016/0092-8674(93)80045-G |
0.707 |
|
| 1993 |
Steinbeisser H, De Robertis EM, Ku M, Kessler DS, Melton DA. Xenopus axis formation: induction of goosecoid by injected Xwnt-8 and activin mRNAs. Development (Cambridge, England). 118: 499-507. PMID 7900991 |
0.496 |
|
| 1992 |
Whitman M, Melton DA. Involvement of p21ras in Xenopus mesoderm induction. Nature. 357: 252-4. PMID 1589022 DOI: 10.1038/357252A0 |
0.323 |
|
| 1992 |
Mowry KL, Melton DA. Vegetal messenger RNA localization directed by a 340-nt RNA sequence element in Xenopus oocytes. Science (New York, N.Y.). 255: 991-4. PMID 1546297 DOI: 10.1126/Science.1546297 |
0.686 |
|
| 1992 |
Sokol SY, Melton DA. Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus. Developmental Biology. 154: 348-55. PMID 1426642 DOI: 10.1016/0012-1606(92)90073-P |
0.413 |
|
| 1992 |
Hemmati-Brivanlou A, Wright DA, Melton DA. Embryonic expression and functional analysis of a Xenopus activin receptor. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 194: 1-11. PMID 1384808 DOI: 10.1002/aja.1001940102 |
0.312 |
|
| 1992 |
Hemmati-Brivanlou A, Melton DA. A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature. 359: 609-14. PMID 1328888 DOI: 10.1038/359609a0 |
0.337 |
|
| 1992 |
Jessell TM, Melton DA. Diffusible factors in vertebrate embryonic induction. Cell. 68: 257-70. PMID 1310256 DOI: 10.1016/0092-8674(92)90469-S |
0.451 |
|
| 1991 |
Sokol S, Melton DA. Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin. Nature. 351: 409-11. PMID 2034291 DOI: 10.1038/351409a0 |
0.394 |
|
| 1991 |
Gururajan R, Perry-O'Keefe H, Melton DA, Weeks DL. The Xenopus localized messenger RNA An3 may encode an ATP-dependent RNA helicase. Nature. 349: 717-9. PMID 1996140 DOI: 10.1038/349717A0 |
0.654 |
|
| 1991 |
Sokol S, Christian JL, Moon RT, Melton DA. Injected Wnt RNA induces a complete body axis in Xenopus embryos. Cell. 67: 741-52. PMID 1834344 DOI: 10.1016/0092-8674(91)90069-B |
0.358 |
|
| 1991 |
O'Keefe HP, Melton DA, Ferreiro B, Kintner C. In situ hyridization. Methods in Cell Biology. 36: 443-63. PMID 1811146 DOI: 10.1016/S0091-679X(08)60291-5 |
0.648 |
|
| 1991 |
Vize PD, Melton DA, Hemmati-Brivanlou A, Harland RM. Assays for gene function in developing Xenopus embryos. Methods in Cell Biology. 36: 367-87. PMID 1811145 DOI: 10.1016/S0091-679X(08)60288-5 |
0.711 |
|
| 1991 |
Melton DA. Pattern formation during animal development. Science (New York, N.Y.). 252: 234-41. PMID 1672778 DOI: 10.1126/Science.1672778 |
0.312 |
|
| 1991 |
Altaba ARI, Choi T, Melton DA. Expression of the Xhox3 homeobox protein in Xenopus embryos: Blocking its early function suggests the requirement of Xhox3 for normal posterior development Development Growth and Differentiation. 33: 651-669. DOI: 10.1111/J.1440-169X.1991.00651.X |
0.335 |
|
| 1990 |
Sokol S, Wong GG, Melton DA. A mouse macrophage factor induces head structures and organizes a body axis in Xenopus. Science (New York, N.Y.). 249: 561-4. PMID 2382134 DOI: 10.1126/Science.2382134 |
0.362 |
|
| 1990 |
Mitrani E, Ziv T, Thomsen G, Shimoni Y, Melton DA, Bril A. Activin can induce the formation of axial structures and is expressed in the hypoblast of the chick. Cell. 63: 495-501. PMID 2225063 DOI: 10.1016/0092-8674(90)90446-L |
0.665 |
|
| 1990 |
Thomsen G, Woolf T, Whitman M, Sokol S, Vaughan J, Vale W, Melton DA. Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell. 63: 485-93. PMID 2225062 DOI: 10.1016/0092-8674(90)90445-K |
0.701 |
|
| 1990 |
Ruiz i Altaba A, Melton DA. Axial patterning and the establishment of polarity in the frog embryo. Trends in Genetics : Tig. 6: 57-64. PMID 2186530 DOI: 10.1016/0168-9525(90)90075-H |
0.341 |
|
| 1989 |
Krieg PA, Varnum SM, Wormington WM, Melton DA. The mRNA encoding elongation factor 1-alpha (EF-1 alpha) is a major transcript at the midblastula transition in Xenopus. Developmental Biology. 133: 93-100. PMID 2707491 DOI: 10.1016/0012-1606(89)90300-X |
0.526 |
|
| 1989 |
Whitman M, Melton DA. Induction of mesoderm by a viral oncogene in early Xenopus embryos. Science (New York, N.Y.). 244: 803-6. PMID 2658054 DOI: 10.1126/Science.2658054 |
0.378 |
|
| 1989 |
Ruiz i Altaba A, Melton DA. Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos. Nature. 341: 33-8. PMID 2570357 DOI: 10.1038/341033a0 |
0.333 |
|
| 1989 |
Ruiz i Altaba A, Melton DA. Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis. Cell. 57: 317-26. PMID 2564813 DOI: 10.1016/0092-8674(89)90969-0 |
0.377 |
|
| 1989 |
Tannahill D, Melton DA. Localized synthesis of the Vg1 protein during early Xenopus development. Development (Cambridge, England). 106: 775-85. PMID 2562668 |
0.618 |
|
| 1988 |
Mercola M, Melton DA, Stiles CD. Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos. Science (New York, N.Y.). 241: 1223-5. PMID 3413486 DOI: 10.1126/Science.3413486 |
0.313 |
|
| 1988 |
Harvey RP, Melton DA. Microinjection of synthetic Xhox-1A homeobox mRNA disrupts somite formation in developing Xenopus embryos. Cell. 53: 687-97. PMID 2897242 DOI: 10.1016/0092-8674(88)90087-6 |
0.346 |
|
| 1987 |
Melton DA. Translocation of a localized maternal mRNA to the vegetal pole of Xenopus oocytes. Nature. 328: 80-2. PMID 3600777 DOI: 10.1038/328080a0 |
0.32 |
|
| 1987 |
Weeks DL, Melton DA. A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta. Cell. 51: 861-7. PMID 3479264 DOI: 10.1016/0092-8674(87)90109-7 |
0.641 |
|
| 1987 |
Krieg PA, Melton DA. An enhancer responsible for activating transcription at the midblastula transition in Xenopus development. Proceedings of the National Academy of Sciences of the United States of America. 84: 2331-5. PMID 3470796 DOI: 10.1073/Pnas.84.8.2331 |
0.609 |
|
| 1987 |
Weeks DL, Melton DA. A maternal mRNA localized to the animal pole of Xenopus eggs encodes a subunit of mitochondrial ATPase. Proceedings of the National Academy of Sciences of the United States of America. 84: 2798-802. PMID 2953029 DOI: 10.1073/Pnas.84.9.2798 |
0.625 |
|
| 1987 |
Krieg PA, Melton DA. In vitro RNA synthesis with SP6 RNA polymerase. Methods in Enzymology. 155: 397-415. PMID 2828872 DOI: 10.1016/0076-6879(87)55027-3 |
0.576 |
|
| 1987 |
Ruiz i Altaba A, Perry-O'Keefe H, Melton DA. Xfin: an embryonic gene encoding a multifingered protein in Xenopus. The Embo Journal. 6: 3065-70. PMID 2826129 DOI: 10.1002/J.1460-2075.1987.Tb02613.X |
0.333 |
|
| 1987 |
Kintner CR, Melton DA. Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction. Development (Cambridge, England). 99: 311-25. PMID 2443340 |
0.564 |
|
| 1986 |
Harvey RP, Tabin CJ, Melton DA. Embryonic expression and nuclear localization of Xenopus homeobox (Xhox) gene products. The Embo Journal. 5: 1237-44. PMID 3015593 DOI: 10.1002/J.1460-2075.1986.Tb04352.X |
0.57 |
|
| 1985 |
Krieg PA, Melton DA. Developmental regulation of a gastrula-specific gene injected into fertilized Xenopus eggs. The Embo Journal. 4: 3463-71. PMID 4092685 DOI: 10.1002/J.1460-2075.1985.Tb04105.X |
0.621 |
|
| 1985 |
Weeks DL, Rebagliati MR, Harvey RP, Melton DA. Localized maternal mRNAs in Xenopus laevis eggs. Cold Spring Harbor Symposia On Quantitative Biology. 50: 21-30. PMID 3006987 DOI: 10.1101/Sqb.1985.050.01.005 |
0.615 |
|
| 1985 |
Rebagliati MR, Weeks DL, Harvey RP, Melton DA. Identification and cloning of localized maternal RNAs from Xenopus eggs. Cell. 42: 769-77. PMID 2414011 DOI: 10.1016/0092-8674(85)90273-9 |
0.639 |
|
| 1984 |
Krieg PA, Melton DA. Formation of the 3' end of histone mRNA by post-transcriptional processing. Nature. 308: 203-6. PMID 6700722 DOI: 10.1038/308203a0 |
0.595 |
|
| 1984 |
Krieg PA, Melton DA. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs. Nucleic Acids Research. 12: 7057-70. PMID 6207484 DOI: 10.1093/nar/12.18.7057 |
0.594 |
|
| 1984 |
Melton DA, Krieg PA, Rebagliati MR, Maniatis T, Zinn K, Green MR. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Research. 12: 7035-56. PMID 6091052 DOI: 10.1093/Nar/12.18.7035 |
0.578 |
|
| 1983 |
Perry HE, Melton DA. A rapid increase in acetylcholinesterase mRNA during ascidian embryogenesis as demonstrated by microinjection into Xenopus laevis oocytes. Cell Differentiation. 13: 233-8. PMID 6141851 DOI: 10.1016/0045-6039(83)90094-5 |
0.366 |
|
| 1982 |
Ciampi MS, Melton DA, Cortese R. Site-directed mutagenesis of a tRNA gene: base alterations in the coding region affect transcription. Proceedings of the National Academy of Sciences of the United States of America. 79: 1388-92. PMID 6951183 DOI: 10.1073/Pnas.79.5.1388 |
0.315 |
|
| 1981 |
Gurdon JB, Melton DA. Gene transfer in amphibian eggs and oocytes. Annual Review of Genetics. 15: 189-218. PMID 7039494 DOI: 10.1146/Annurev.Ge.15.120181.001201 |
0.484 |
|
| 1981 |
Cortese R, Harland R, Melton D. Transcription of tRNA genes in vivo: single-stranded compared to double-stranded templates. Proceedings of the National Academy of Sciences of the United States of America. 77: 4147-51. PMID 7001455 DOI: 10.1073/PNAS.77.7.4147 |
0.492 |
|
| 1981 |
Miller JR, Melton DA. A transcriptionally active pseudogene in xenopus laevis oocyte 5S DNA. Cell. 24: 829-35. PMID 6166389 DOI: 10.1016/0092-8674(81)90108-2 |
0.306 |
|
| 1980 |
Melton DA, Cortese R, de Robertis EM, Trendelenburg MF, Gurdon JB. Gene injection into amphibian oocytes. Results and Problems in Cell Differentiation. 11: 8-14. PMID 7444205 DOI: 10.1007/978-3-540-38267-6_2 |
0.645 |
|
| 1980 |
Melton DA, De Robertis EM, Cortese R. Order and intracellular location of the events involved in the maturation of a spliced tRNA. Nature. 284: 143-8. PMID 6987526 DOI: 10.1038/284143a0 |
0.524 |
|
| 1979 |
Melton DA, Cortese R. Transcription of cloned tRNA genes and the nuclear partitioning of a tRNA precursor. Cell. 18: 1165-72. PMID 391407 DOI: 10.1016/0092-8674(79)90229-0 |
0.305 |
|
| 1979 |
Gurdon JB, Melton DA, De Robertis EM. Genetics in an oocyte. Ciba Foundation Symposium. 63-80. PMID 289482 DOI: 10.1002/9780470720486.ch5 |
0.583 |
|
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